|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
2-428 |
0e+00 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 720.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 2 FLAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:PRK15445 1 LLAIAIFLLTLVLVIWQPKGLGIGWSALLGAVLALLTGVVSLGDVPVVWGIVWNATLTFIAIIIISLLLDEAGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 82 HVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLAFVMAAGFIADTASLPLIVSNLVN 161
Cdd:PRK15445 81 HVARWAKGNGRKLFVYIVLLGAAVAALFANDGAALILTPIVLAMLLALGFSKKATLAFVMAAGFIADTASLPLVVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 162 IVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKTPASVIKDPATFRAGWIVLLLLLVGFFVL 241
Cdd:PRK15445 161 IVSADYFGIGFAEYASVMVPVNLVSLAASLLVLWLYFRKDIPKTYDLELLKEPASAIKDPALFKLGWIVLALLLVGYFVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 242 EPLGIPVSAIAATGAAVLFIVAKRGHTINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAAT 321
Cdd:PRK15445 241 EPLGIPVSAIAGVGALILLLVARRGHAINTKKVLKGAPWQIVIFSLGMYLVVYGLRNAGLTDYLAGVLNYLADQGLFAAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 322 FGTGLLTAFLSSVMNNMPTVLIGALSIDGSTATGIVKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWGY 401
Cdd:PRK15445 321 LGTGFLAAFLSSVMNNMPTVLIGALAIDGSNATGVIKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*..
gi 446399834 402 YFRTGIIMTLPVLFVTLAALALRLSIT 428
Cdd:PRK15445 401 YFKVGIIITLPVLLVTLLALALRLSLF 427
|
|
| 2a45 |
TIGR00935 |
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a ... |
2-427 |
0e+00 |
|
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a highly hydrophobic integral membrane protein involved in transport processes used to protect cells from arsenite (or antimonite). Members of the seed alignment were selected by adjacency to the ATPase subunit ArsA that energizes the transport. [Cellular processes, Detoxification, Transport and binding proteins, Other]
Pssm-ID: 213571 Cd Length: 426 Bit Score: 575.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 2 FLAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:TIGR00935 1 ILAVLIFLLTLVLVIWQPKGLGIGWSATIGAVLALLSGVVSFGDVPVVTGIVWNATLTFVAIIIISLILDEIGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 82 HVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLAFVMAAGFIADTASLPLIVSNLVN 161
Cdd:TIGR00935 81 HMARWAKGNGRKMFIYISLLGAIVAALFANDGAALILTPIVLAMVRALGFDEAAVLPFIMASGFIADTTSLPLIVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 162 IVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKTPASVIKDPATFRAGWIVLLLLLVGFFVL 241
Cdd:TIGR00935 161 IVSADFFGIGFNEYAAVMIPPNIFALIASILVLYLYFRKDIPARYDVSQLREPKEAIKDQKLFKFSWVVLALLLVGYFGS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 242 EPLGIPVSAIAATGAAVLFIVAKRGHTINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAAT 321
Cdd:TIGR00935 241 EFLNIPVSFVAATIALIFLVVAAKSHAVDTRKVIKGAPWNIVVFSLGMYLVVYGLRNVGLTDLLAGVLDYFADQGLFVAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 322 FGTGLLTAFLSSVMNNMPTVLIGALSIDGSTATGIVKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWGY 401
Cdd:TIGR00935 321 MGMGFLAAFLSSIMNNMPTVLINALSIDGSNATGVMKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*.
gi 446399834 402 YFRTGIIMTLPVLFVTLAALALRLSI 427
Cdd:TIGR00935 401 YFKVGIVITVPVLFITLAGLYLRLSI 426
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
3-422 |
5.80e-160 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 457.50 E-value: 5.80e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 3 LAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALH 82
Cdd:cd01118 1 LAIAIFVLTLVLVIWRPFGLPEAVWAVLGAVIALILGLVSPHDALEVWGIVWDVTLTLIGVILLSLLLDEEGFFEWVAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 83 VSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLAFVMAAGFIADTASLPLIVSNLVNI 162
Cdd:cd01118 81 AARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPFLYACAFIADAASLPLPISNLVNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 163 VSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKTPASVIKDPATFRAGWIVLLLLLVGFFVLE 242
Cdd:cd01118 161 VTAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRALPKRLETASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 243 PLGIPVSAIAATGAAVLFIVAKRGHTINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAATF 322
Cdd:cd01118 241 ILLIPPSFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAIL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 323 GTGLLTAFLSSVMNNMPTVLIGALSIDGstatGIVKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWGYY 402
Cdd:cd01118 321 GVGLLAAFLSNVMNNLPAVLIGALALAA----GHAPEALVYANLIGVDLGPKLTPIGSLATLLWLHVLRRKGIRVSWGYY 396
|
410 420
....*....|....*....|
gi 446399834 403 FRTGIIMTLPVLFVTLAALA 422
Cdd:cd01118 397 LKVGLIVTPPVLVVTLAALI 416
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
1-425 |
2.75e-103 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 312.83 E-value: 2.75e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 1 MFLAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVwnIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:COG1055 2 MILALAIFVLTYLLIILEPRGLNRAVAALLGAALLLLLGVVSLEDALEA--IDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 81 LHVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSqgtTLAFVMAAGFIADTASLPLIVSNLV 160
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLN---PVPFLIAIVFAANIGGAATPIGNPT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 161 NIVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSllKTPASVIKDPATFRAGWIVLLLLLVGFFV 240
Cdd:COG1055 157 NIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLE--DDPKEAIKDRRLLRISLLVLALLLVGFVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 241 LEPLGIPVSAIAATGAAVLFIVAKrghtINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAA 320
Cdd:COG1055 235 HSFLGLPPALIALLGAAVLLLLAR----VDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 321 TFGTGLLTAFLSSVMNNMPTVLIGALSIDGSTATGIVkEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWG 400
Cdd:COG1055 311 ALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNP-EPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFG 389
|
410 420
....*....|....*....|....*
gi 446399834 401 YYFRTGIIMTLPVLFVTLAALALRL 425
Cdd:COG1055 390 EFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB |
pfam02040 |
Arsenical pump membrane protein; |
1-418 |
4.56e-82 |
|
Arsenical pump membrane protein;
Pssm-ID: 460426 Cd Length: 423 Bit Score: 258.75 E-value: 4.56e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 1 MFLAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:pfam02040 4 FIFALFIFLLILQLKILQIGNLACGGAACAGAAGALIAGDVLFHDGITVNAILAFAAIAFIAIILDNIGFDEIAAFEMAA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 81 LHVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLAFVMAAGFIADTASLPLIVSNLV 160
Cdd:pfam02040 84 AAKAKAAKGFGVRMFLGAILAAAFAAAGAALDGAAIILAMIRAAHFNAKHFFEFIIAPFFIADGFIADFTSLNFVNINLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 161 NIVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKTPASVIKDPATFRAGWIVLLLLLVGFFV 240
Cdd:pfam02040 164 DIFHADFFDIAFIDVAPRLFSLLAFIILASIFFLKLFFKKSDLKEVDKPEEAIKDEAIFDLNMFILGLLIIGLFAIEFFA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 241 LEPLGIPVSAIAATGAAVLFIVAKRGHTINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAA 320
Cdd:pfam02040 244 IEFFSIAGSIAAGFIAAAFKIAAQHSKAVHKEAPVAEAFFAIGFFSIGMGVRNAGLRDAGLDDILAAADQAAAAGGIFAG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 321 TFGTGLLTAFLSSVMNNMPTVLIGALSIDGSTATGIVKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWG 400
Cdd:pfam02040 324 FIAAGFIAAILNLIMNMIDALAIAALAIAGMDREALIRAALIGADLGGKDLGIGILAIGLLAHLLSHHGLKHKGGKIFKG 403
|
410
....*....|....*...
gi 446399834 401 YYFRTGIIMTLPVLFVTL 418
Cdd:pfam02040 404 GIFKTGIILLIPLLGITI 421
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
2-428 |
0e+00 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 720.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 2 FLAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:PRK15445 1 LLAIAIFLLTLVLVIWQPKGLGIGWSALLGAVLALLTGVVSLGDVPVVWGIVWNATLTFIAIIIISLLLDEAGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 82 HVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLAFVMAAGFIADTASLPLIVSNLVN 161
Cdd:PRK15445 81 HVARWAKGNGRKLFVYIVLLGAAVAALFANDGAALILTPIVLAMLLALGFSKKATLAFVMAAGFIADTASLPLVVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 162 IVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKTPASVIKDPATFRAGWIVLLLLLVGFFVL 241
Cdd:PRK15445 161 IVSADYFGIGFAEYASVMVPVNLVSLAASLLVLWLYFRKDIPKTYDLELLKEPASAIKDPALFKLGWIVLALLLVGYFVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 242 EPLGIPVSAIAATGAAVLFIVAKRGHTINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAAT 321
Cdd:PRK15445 241 EPLGIPVSAIAGVGALILLLVARRGHAINTKKVLKGAPWQIVIFSLGMYLVVYGLRNAGLTDYLAGVLNYLADQGLFAAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 322 FGTGLLTAFLSSVMNNMPTVLIGALSIDGSTATGIVKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWGY 401
Cdd:PRK15445 321 LGTGFLAAFLSSVMNNMPTVLIGALAIDGSNATGVIKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*..
gi 446399834 402 YFRTGIIMTLPVLFVTLAALALRLSIT 428
Cdd:PRK15445 401 YFKVGIIITLPVLLVTLLALALRLSLF 427
|
|
| 2a45 |
TIGR00935 |
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a ... |
2-427 |
0e+00 |
|
arsenite/antimonite efflux pump membrane protein; Members of this protein family are ArsB, a highly hydrophobic integral membrane protein involved in transport processes used to protect cells from arsenite (or antimonite). Members of the seed alignment were selected by adjacency to the ATPase subunit ArsA that energizes the transport. [Cellular processes, Detoxification, Transport and binding proteins, Other]
Pssm-ID: 213571 Cd Length: 426 Bit Score: 575.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 2 FLAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAAL 81
Cdd:TIGR00935 1 ILAVLIFLLTLVLVIWQPKGLGIGWSATIGAVLALLSGVVSFGDVPVVTGIVWNATLTFVAIIIISLILDEIGFFEWAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 82 HVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLAFVMAAGFIADTASLPLIVSNLVN 161
Cdd:TIGR00935 81 HMARWAKGNGRKMFIYISLLGAIVAALFANDGAALILTPIVLAMVRALGFDEAAVLPFIMASGFIADTTSLPLIVSNLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 162 IVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKTPASVIKDPATFRAGWIVLLLLLVGFFVL 241
Cdd:TIGR00935 161 IVSADFFGIGFNEYAAVMIPPNIFALIASILVLYLYFRKDIPARYDVSQLREPKEAIKDQKLFKFSWVVLALLLVGYFGS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 242 EPLGIPVSAIAATGAAVLFIVAKRGHTINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAAT 321
Cdd:TIGR00935 241 EFLNIPVSFVAATIALIFLVVAAKSHAVDTRKVIKGAPWNIVVFSLGMYLVVYGLRNVGLTDLLAGVLDYFADQGLFVAT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 322 FGTGLLTAFLSSVMNNMPTVLIGALSIDGSTATGIVKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWGY 401
Cdd:TIGR00935 321 MGMGFLAAFLSSIMNNMPTVLINALSIDGSNATGVMKEAMIYANVIGSDLGPKITPIGSLATLLWLHVLAQKGVKISWGY 400
|
410 420
....*....|....*....|....*.
gi 446399834 402 YFRTGIIMTLPVLFVTLAALALRLSI 427
Cdd:TIGR00935 401 YFKVGIVITVPVLFITLAGLYLRLSI 426
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
3-422 |
5.80e-160 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 457.50 E-value: 5.80e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 3 LAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALH 82
Cdd:cd01118 1 LAIAIFVLTLVLVIWRPFGLPEAVWAVLGAVIALILGLVSPHDALEVWGIVWDVTLTLIGVILLSLLLDEEGFFEWVAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 83 VSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLAFVMAAGFIADTASLPLIVSNLVNI 162
Cdd:cd01118 81 AARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPFLYACAFIADAASLPLPISNLVNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 163 VSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKTPASVIKDPATFRAGWIVLLLLLVGFFVLE 242
Cdd:cd01118 161 VTAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRALPKRLETASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 243 PLGIPVSAIAATGAAVLFIVAKRGHTINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAATF 322
Cdd:cd01118 241 ILLIPPSFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAIL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 323 GTGLLTAFLSSVMNNMPTVLIGALSIDGstatGIVKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWGYY 402
Cdd:cd01118 321 GVGLLAAFLSNVMNNLPAVLIGALALAA----GHAPEALVYANLIGVDLGPKLTPIGSLATLLWLHVLRRKGIRVSWGYY 396
|
410 420
....*....|....*....|
gi 446399834 403 FRTGIIMTLPVLFVTLAALA 422
Cdd:cd01118 397 LKVGLIVTPPVLVVTLAALI 416
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
1-425 |
2.75e-103 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 312.83 E-value: 2.75e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 1 MFLAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVwnIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:COG1055 2 MILALAIFVLTYLLIILEPRGLNRAVAALLGAALLLLLGVVSLEDALEA--IDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 81 LHVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSqgtTLAFVMAAGFIADTASLPLIVSNLV 160
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLN---PVPFLIAIVFAANIGGAATPIGNPT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 161 NIVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSllKTPASVIKDPATFRAGWIVLLLLLVGFFV 240
Cdd:COG1055 157 NIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLE--DDPKEAIKDRRLLRISLLVLALLLVGFVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 241 LEPLGIPVSAIAATGAAVLFIVAKrghtINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAA 320
Cdd:COG1055 235 HSFLGLPPALIALLGAAVLLLLAR----VDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 321 TFGTGLLTAFLSSVMNNMPTVLIGALSIDGSTATGIVkEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWG 400
Cdd:COG1055 311 ALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNP-EPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFG 389
|
410 420
....*....|....*....|....*
gi 446399834 401 YYFRTGIIMTLPVLFVTLAALALRL 425
Cdd:COG1055 390 EFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB |
pfam02040 |
Arsenical pump membrane protein; |
1-418 |
4.56e-82 |
|
Arsenical pump membrane protein;
Pssm-ID: 460426 Cd Length: 423 Bit Score: 258.75 E-value: 4.56e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 1 MFLAGSIFLLTLVLVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA 80
Cdd:pfam02040 4 FIFALFIFLLILQLKILQIGNLACGGAACAGAAGALIAGDVLFHDGITVNAILAFAAIAFIAIILDNIGFDEIAAFEMAA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 81 LHVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLAFVMAAGFIADTASLPLIVSNLV 160
Cdd:pfam02040 84 AAKAKAAKGFGVRMFLGAILAAAFAAAGAALDGAAIILAMIRAAHFNAKHFFEFIIAPFFIADGFIADFTSLNFVNINLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 161 NIVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKTPASVIKDPATFRAGWIVLLLLLVGFFV 240
Cdd:pfam02040 164 DIFHADFFDIAFIDVAPRLFSLLAFIILASIFFLKLFFKKSDLKEVDKPEEAIKDEAIFDLNMFILGLLIIGLFAIEFFA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 241 LEPLGIPVSAIAATGAAVLFIVAKRGHTINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAA 320
Cdd:pfam02040 244 IEFFSIAGSIAAGFIAAAFKIAAQHSKAVHKEAPVAEAFFAIGFFSIGMGVRNAGLRDAGLDDILAAADQAAAAGGIFAG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 321 TFGTGLLTAFLSSVMNNMPTVLIGALSIDGSTATGIVKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWG 400
Cdd:pfam02040 324 FIAAGFIAAILNLIMNMIDALAIAALAIAGMDREALIRAALIGADLGGKDLGIGILAIGLLAHLLSHHGLKHKGGKIFKG 403
|
410
....*....|....*...
gi 446399834 401 YYFRTGIIMTLPVLFVTL 418
Cdd:pfam02040 404 GIFKTGIILLIPLLGITI 421
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
14-421 |
4.25e-64 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 210.95 E-value: 4.25e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 14 LVIWQPRGLSIGWSASIGAALALGTGVIHIDDIPVVwnIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRRGNGRGRL 93
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSA--IDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGSRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 94 LFtWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQgtTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLSFT 173
Cdd:cd00625 79 LL-LLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSP--PVPLLLALAFAANIGGAATPIGNPPNLIIASLSGLGFL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 174 QYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKTPASVIKDPATFRAGWIVLLLLLVGFFVLEpLGIPVSAIAA 253
Cdd:cd00625 156 DFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDKLTVLAEPLPARPLLKKFLLLALLLLLLFVLLFF-FLIPLGLIAL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 254 TGAAVLFIVAKRGhtINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAATFGTGLLTAFLSS 333
Cdd:cd00625 235 LGALLLLLLLVRG--LDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 334 VMNNMPTVLIGALSIDGSTATgivkEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWGYYFRTGIIMTLPV 413
Cdd:cd00625 313 FISNVPTVALLLPIAASLAPP----EPAWLALALGSTLGGNLTLIGSLANLIPLGAAENAGVGISFGEFLKVGLPLTLLS 388
|
....*...
gi 446399834 414 LFVTLAAL 421
Cdd:cd00625 389 LVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
12-364 |
8.26e-35 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 132.05 E-value: 8.26e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 12 LVLVIWQPrgLSIGWSASIGAALALGTGVIHIDDIpvVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRRGNGRG 91
Cdd:pfam03600 1 YVLIITEK--LPRDVVALLGAVLLVLLGVLTPEEA--LSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 92 RLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSqgtTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLS 171
Cdd:pfam03600 77 RRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLP---PSPLLIALAFAANIGGTATPIGDPPNIIIASALGLS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 172 FTQYASVMIPVDVVAIAAT-LVMLHLFFRRNIPATYDVSLLKTPAS--VIKDPATFRAGWIVLLLLLVGFFVLEPLGIPV 248
Cdd:pfam03600 154 FGDFGFFMFPPVGVALLLVgLLPLLLIFRKLLPVRKEEEAELEELRkrAIKDKLLLAISALVLALVILGFLLLSVLALAG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 249 SAIAATgaavlfivakrGHTINTGKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAvkGLWAATFGTGLLT 328
Cdd:pfam03600 234 ALLLLL-----------TGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGLS--GLLVALALILWLS 300
|
330 340 350
....*....|....*....|....*....|....*.
gi 446399834 329 AFLSSVMNNMPTVLIGALSIDGSTATGIVKEAMIYA 364
Cdd:pfam03600 301 ALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLA 336
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
8-425 |
3.08e-25 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 106.57 E-value: 3.08e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 8 FLLTLVLVIWQPRGLSIgwSASIGAALALGTGVIHIDDIP--VVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSR 85
Cdd:cd01116 1 FIITYALIIFEKVHRTV--AALAGALWLVILGLATLSPDLetIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 86 RGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGfsqGTTLAFVMAAGFIADTASLPLIVSNLVNIVSA 165
Cdd:cd01116 79 ISKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLG---LNPVPVLISEVIAANIGGAATLIGDPPNIMIG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 166 DFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLKT---PASVIKDPATFRAGWIVLLLLLVGFFVLE 242
Cdd:cd01116 156 SAAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLALAelePKYPIKDKVLLLKSLTILTLVIIGFVLHS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 243 PLGIPVSAIAATGAAVLFIVAKRGHTINtgkVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNLLAVKGLWAATF 322
Cdd:cd01116 236 PLGVSLGWIALLGALLLLLLADKLDFED---VLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVI 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 323 GTGLLTAFLSSVMNNMPTVLIGA-LSIDGSTATGIVKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNITIAWGY 401
Cdd:cd01116 313 LILWISALLSAFIDNIPVTATMIpIVKDLASQLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWE 392
|
410 420
....*....|....*....|....
gi 446399834 402 YFRTGiimtLPVLFVTLAALALRL 425
Cdd:cd01116 393 FLKVG----FPIMLVSLILATVYL 412
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
27-421 |
1.28e-18 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 86.95 E-value: 1.28e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 27 SASIGAALALGTGVIHIDDIPVVwnIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRRGNGRGRLLFTwIVLLGAAVA 106
Cdd:cd01117 16 IALLGAALMLLFGVISLEDAPAA--IDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGSPRRLLFL-LVLLSGILS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 107 ALFANDGAALILTPIVIAMLLALGFSqgtTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLSFTQYASVMIPVDVVA 186
Cdd:cd01117 93 ALLTNDTACLVFTPIVLELARVAGLP---PIPLLLALATAANIGSAATPIGNPQNLLIASESGISFPFFLAAMAPLALLG 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 187 IAATLVMLHLFFRRNIPATYDVSLLKtPASVIKDPATFRAGWIVLLLLLVGFFVLEPLGIPVSAIAATGAAVLFIVAKRg 266
Cdd:cd01117 170 LLLLLILLLVLFPGELKGLPLDKATK-EEGVGARKLAVKLLVLILLLLVAFLALLGVIPLWTAALVAAVLLLLTRLKPR- 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 267 htintgKVLRSAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVL-NLLAVKGLWaatfgtgLLTAFLSSVMNNMPTVLIGA 345
Cdd:cd01117 248 ------RVLKKVDWGLLLFFAGLFILVGGFAQGLPLEGLSRLLpLLDSVLSLF-------LVSIGLSQLISNVPAVLLLL 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446399834 346 LSIDGSTATGIVKEAMiyanviGCDLGPKITPIGSLATLLWLHVLAQKNITIAWGYYFRTGIIMTLPVLFVTLAAL 421
Cdd:cd01117 315 PFLPSADEKDWLLLAA------GSTIAGNLTLLGSAANLIVAEAAERRGVRLSFGEFLKYGVPLTLLTAAIGILWL 384
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
61-423 |
7.58e-12 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 66.33 E-value: 7.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 61 IAVIIISLLLDESGFFEWAALHVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLA-- 138
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEKRSKFGsa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 139 FVMAAGFIADTASLPLIVSNLVNIVSADFF------GLSFTQYASVMIPVDVVAIAATLVMLHLFFRRNIPATYDVSLLK 212
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAGLLeeatgiPISFFEWMLVGLPVALVGLLLLWLVLYRLLPPEIKEVPGSKEVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 213 TPASVIKDPATFRAGW--IVLLLLLVGFFVLEPLGIPVSAIAATGAAVLFIVakrgHTINTGKVLRSAPWQIVIFSLGMY 290
Cdd:COG0471 161 REELAELGPLSRREKIalAIFALTVLLWITGSLHGIPIAVVALLGAVLLLLT----GVLTWKDAYKSIPWGVLLLFGGGL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 291 LVVYGLRNAGLTEYLSD-VLNLLAVKGLWAATFGTGLLTAFLSSVMNNMPTV-LIGALSIDGSTATGIVKEAMIYANVIG 368
Cdd:COG0471 237 ALGAALEKTGLAAWLADaLLPLLGGLSPLLLLLLLALLTLLLTEFASNTATAaLLLPIAISLAQALGVNPLPLALAVAFA 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 446399834 369 CDLGPkITPIGSLATLLwlhVLAQKNITIawGYYFRTGIIMTLPVLFVTLAALAL 423
Cdd:COG0471 317 ASCAF-LLPVGTPPNAI---VYGSGYYKF--KDFLKVGLPLNLIGLVVLLLLGPL 365
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
3-199 |
8.28e-09 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 57.09 E-value: 8.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 3 LAGSIFLLTLVLVIWQP-RGLSIGWSASIGAALALGTGVIHIDDI--PVVWNIVWnataAFIAVIIISLLLDESGFFEWA 79
Cdd:COG0471 176 IALAIFALTVLLWITGSlHGIPIAVVALLGAVLLLLTGVLTWKDAykSIPWGVLL----LFGGGLALGAALEKTGLAAWL 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 80 ALHVSRRGNGRGRLLFTWIVLLGAAVAALFANDGA-ALILTPIVIAMLLALGFSqgtTLAFVMAAGFIADTASLpLIVSN 158
Cdd:COG0471 252 ADALLPLLGGLSPLLLLLLLALLTLLLTEFASNTAtAALLLPIAISLAQALGVN---PLPLALAVAFAASCAFL-LPVGT 327
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446399834 159 LVNIVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFR 199
Cdd:COG0471 328 PPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLWWP 368
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
60-369 |
1.93e-06 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 49.51 E-value: 1.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 60 FIAVIIISLLLDESGFFEWAALHVSRRGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSQGTTLAF 139
Cdd:cd01115 52 FLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPSRLLMP 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 140 VMAAGFIADTASLpliVSNLVNIVSADFFGLSFTQYASVMIPVDVVAIAATLVMLHLFFrrnipatydvsllktpasvik 219
Cdd:cd01115 132 LAFAASIGGMLTL---IGTPPNLVASGYLESLGGQGFSFFEFTPIGLPLLIIGLLYLWF--------------------- 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 220 dpaTFRAGWIVLLLLLVGFFVLEPLGIPVSAIAATGAAVLFIVAKrghtINTGKVLRSAPWQIVIFSLGMYLVVYGLRNA 299
Cdd:cd01115 188 ---IFRLAVLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGV----LLTKEDYKSIDWGIIFLFAGGIPLGKALESS 260
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446399834 300 GLTEYLSD-VLNLLAVKGLWAATFGTGLLTAFLSSVMNNMPTVLIGA-LSIDGSTATGIVKEAMIYANVIGC 369
Cdd:cd01115 261 GAAALIAEaLISLLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLApIALSIALSLGLPPEALLLAVAIGA 332
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
28-198 |
1.34e-03 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 40.65 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 28 ASIGAALALGTGVIHIDDipVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRRGNGRGRLLFTWIVLLGAAVAA 107
Cdd:cd01115 217 IAIGAIVLVFGGVLLTKE--DYKSIDWGIIFLFAGGIPLGKALESSGAAALIAEALISLLGGLPPFAILLLLCLLTLVLT 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446399834 108 LF-ANDGAALILTPIVIAMLLALGFSqgtTLAFVMAAGFIADTASLpLIVSNLVNIVSADFFGLSFTQYASVMIPVDVVA 186
Cdd:cd01115 295 NFiSNTATAVLLAPIALSIALSLGLP---PEALLLAVAIGASCAFM-LPVGTPPNAIVLGPGGYKFSDFAKVGLPLSILS 370
|
170
....*....|..
gi 446399834 187 IAATLVMLHLFF 198
Cdd:cd01115 371 LVVSVTMIPLIW 382
|
|
| |
