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MULTISPECIES: ATP-dependent DNA helicase [Bacillus]
Protein Classification
ATP-dependent DNA helicase ( domain architecture ID 11439892 )
DNA helicase utilizes the energy from ATP hydrolysis to unwind double-stranded DNA, similar to XPD helicases, which play an important role in nucleotide excision repair pathway
List of domain hits
Name
Accession
Description
Interval
E-value
DinG
COG1199 Rad3-related DNA helicase DinG [Replication, recombination and repair];
36-621
7.03e-158
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain]
Cd Length: 629
Bit Score: 468.25
E-value: 7.03e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 36 K GFE E R DE Q IF MA FQLE RA FQ E KKVMFA EAG V G N GKT IV YL LY A ICY AR Y TGK PAI I AC A DET L I EQLV KE eg D IAK L SE 115
Cdd:COG1199 11 P GFE P R PG Q RE MA EAVA RA LA E GRHLLI EAG T G T GKT LA YL VP A LLA AR E TGK KVV I ST A TKA L Q EQLV EK -- D LPL L RK 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 116 ALGL SVD V R L A K SMD NYLCLR K LE DVMSGRAPEVI E DVYYELPQ fvfdhg TMQNF T HY GDR K E F PL - LN DE E W SK V NW D Y 194
Cdd:COG1199 89 ALGL PLR V A L L K GRS NYLCLR R LE QALQEGDDLDD E ELLLARIL ------ AWASE T WT GDR D E L PL p ED DE L W RQ V TS D A 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 195 FQ d C F -- T C DSRHR C GQT L S R EHY R K a AD LIICSQDFYMDHIWTYD arkregqi P LLPE SSCVVF DE G H LVEYA A QKALT 272
Cdd:COG1199 163 DN - C L gr R C PYYGV C PYE L A R RLA R E - AD VVVVNHHLLFADLALGE -------- E LLPE DDVLII DE A H NLPDR A RDMFS 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 273 YR L KQTMMEQ LL TR L LQNDI R EEFAH L --- V E ETIWQTERF F DV L Q E NKKEIAGSDR L E i TVT E KVTAEAKR L YAKIGEV 349
Cdd:COG1199 233 AE L SSRSLLR LL RE L RKLGL R PGLKK L ldl L E RLREALDDL F LA L E E EEELRLALGE L P - DEP E ELLEALDA L RDALEAL 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 350 GD AL vfes E MHTVNTYD L NIVD E H L DV L EHS L RL F --- MHEKNVIT W G E EGD G AFT L VIM P RAVEEV L Q E KV FS KKIPYI 426
Cdd:COG1199 312 AE AL ---- E EELERLAE L DALL E R L EE L LFA L AR F lri AEDEGYVR W L E REG G DVR L HAA P LDPADL L R E LL FS RARSVV 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 427 FS SATLS NNDS F SFT A NS LG V - K D YLSF S VA SPFDYE E Q M --- AVNL L SHTKENE -- W E RKCQYTL E NIQKTN G R TLVLF 500
Cdd:COG1199 388 LT SATLS VGGP F DYF A RR LG L d E D ARTL S LP SPFDYE N Q A lly VPRD L PRPSDRD gy L E AIAEAIA E LLEASG G N TLVLF 467
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 501 RTTQE L AAFK E YV s K E QMSV P F L YE GD QEISQ L VS RF QNEEET VL CAV - HL WEG L D I PG SS LS H VII WS LPFP - P N DPV F 578
Cdd:COG1199 468 TSYRA L EQVA E LL - R E RLDI P V L VQ GD GSREA L LE RF REGGNS VL VGT g SF WEG V D L PG DA LS L VII VK LPFP p P D DPV L 546
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 446415829 579 EA K R KHVN ---- DP F WDVDV P YMILR L R QG I GRLIR TSD D K G AISIF 621
Cdd:COG1199 547 EA R R EALE argg NG F MYAYL P PAVIK L K QG A GRLIR SEE D R G VVVLL 593
Name
Accession
Description
Interval
E-value
DinG
COG1199 Rad3-related DNA helicase DinG [Replication, recombination and repair];
36-621
7.03e-158
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain]
Cd Length: 629
Bit Score: 468.25
E-value: 7.03e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 36 K GFE E R DE Q IF MA FQLE RA FQ E KKVMFA EAG V G N GKT IV YL LY A ICY AR Y TGK PAI I AC A DET L I EQLV KE eg D IAK L SE 115
Cdd:COG1199 11 P GFE P R PG Q RE MA EAVA RA LA E GRHLLI EAG T G T GKT LA YL VP A LLA AR E TGK KVV I ST A TKA L Q EQLV EK -- D LPL L RK 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 116 ALGL SVD V R L A K SMD NYLCLR K LE DVMSGRAPEVI E DVYYELPQ fvfdhg TMQNF T HY GDR K E F PL - LN DE E W SK V NW D Y 194
Cdd:COG1199 89 ALGL PLR V A L L K GRS NYLCLR R LE QALQEGDDLDD E ELLLARIL ------ AWASE T WT GDR D E L PL p ED DE L W RQ V TS D A 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 195 FQ d C F -- T C DSRHR C GQT L S R EHY R K a AD LIICSQDFYMDHIWTYD arkregqi P LLPE SSCVVF DE G H LVEYA A QKALT 272
Cdd:COG1199 163 DN - C L gr R C PYYGV C PYE L A R RLA R E - AD VVVVNHHLLFADLALGE -------- E LLPE DDVLII DE A H NLPDR A RDMFS 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 273 YR L KQTMMEQ LL TR L LQNDI R EEFAH L --- V E ETIWQTERF F DV L Q E NKKEIAGSDR L E i TVT E KVTAEAKR L YAKIGEV 349
Cdd:COG1199 233 AE L SSRSLLR LL RE L RKLGL R PGLKK L ldl L E RLREALDDL F LA L E E EEELRLALGE L P - DEP E ELLEALDA L RDALEAL 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 350 GD AL vfes E MHTVNTYD L NIVD E H L DV L EHS L RL F --- MHEKNVIT W G E EGD G AFT L VIM P RAVEEV L Q E KV FS KKIPYI 426
Cdd:COG1199 312 AE AL ---- E EELERLAE L DALL E R L EE L LFA L AR F lri AEDEGYVR W L E REG G DVR L HAA P LDPADL L R E LL FS RARSVV 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 427 FS SATLS NNDS F SFT A NS LG V - K D YLSF S VA SPFDYE E Q M --- AVNL L SHTKENE -- W E RKCQYTL E NIQKTN G R TLVLF 500
Cdd:COG1199 388 LT SATLS VGGP F DYF A RR LG L d E D ARTL S LP SPFDYE N Q A lly VPRD L PRPSDRD gy L E AIAEAIA E LLEASG G N TLVLF 467
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 501 RTTQE L AAFK E YV s K E QMSV P F L YE GD QEISQ L VS RF QNEEET VL CAV - HL WEG L D I PG SS LS H VII WS LPFP - P N DPV F 578
Cdd:COG1199 468 TSYRA L EQVA E LL - R E RLDI P V L VQ GD GSREA L LE RF REGGNS VL VGT g SF WEG V D L PG DA LS L VII VK LPFP p P D DPV L 546
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 446415829 579 EA K R KHVN ---- DP F WDVDV P YMILR L R QG I GRLIR TSD D K G AISIF 621
Cdd:COG1199 547 EA R R EALE argg NG F MYAYL P PAVIK L K QG A GRLIR SEE D R G VVVLL 593
PRK08074
PRK08074 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
18-621
7.66e-62
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain]
Cd Length: 928
Bit Score: 221.36
E-value: 7.66e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 18 Y D KLN E WIGDVFYDIL P ek GF E E R DE Q IF M AFQLER A FQEKKVMFA EAG V G N GK TIV YLL Y A ICY A RYTGK P AI I ACADE 97
Cdd:PRK08074 238 F D AFL E KTEEKLSLAM P -- KY E K R EG Q QE M MKEVYT A LRDSEHALI EAG T G T GK SLA YLL P A AYF A KKKEE P VV I STYTI 315
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 98 T L IE QL V ke E G DI AK L SEALGLS V DVR L A K SMDN YLCLRK L E DVMS grapev I ED VY Y E ----------- L PQ fvfdhgt 166
Cdd:PRK08074 316 Q L QQ QL L -- E K DI PL L QKIFPFP V EAA L L K GRSH YLCLRK F E QALQ ------ E ED DN Y D valtkaqllvw L TE ------- 380
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 167 mqnf T HY GD RK E ---------- FPLLNDEEW S KV ---- N W dy F QD CF TCDSRH R C gqtlsrehyr K A ADL I I CSQDFYM d 232
Cdd:PRK08074 381 ---- T ET GD LD E lnlpsggkll WNRIASDGE S DG gkqs P W -- F SR CF YQRAKN R A ---------- K F ADL V I TNHALLL - 443
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 233 HIW T YDA rkregqi PLLP ESSCVVF DE G H LV E Y AA Q ------------ KA L TY RL KQTMMEQ LL TR L LQ ----------- 289
Cdd:PRK08074 444 TDL T SEE ------- PLLP SYEHIII DE A H HF E E AA S rhlgeqfsymsf QL L LS RL GTLEEDG LL SK L AK lfkksdqasrs 516
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 290 -- N D IR E EFAH L VE E T iwqt ERF F DV L Q ------- ENKKEIAGSD R LE ------------ ITVTEKVTAEAKR L YAKIGE 348
Cdd:PRK08074 517 sf R D LD E SLKE L KF E A ---- DEL F QM L R sfvlkrk KQEQNGRLIY R YN tesekgklwdai TELANRLCYDLRD L LTLLEA 592
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 349 VGDA L -- VF ESE MHTV n T YDLNIVDEH L DVLEHS L R L f MH E K -- NVI TW G E - EGD GA FTLVIM --- P RA V E E V L QEKV F S 420
Cdd:PRK08074 593 QKKE L qe KM ESE SAFL - T GEYAHLIDL L EKMAQL L Q L - LF E E dp DYV TW I E i DAK GA INATRL yaq P VE V A E R L ADEF F A 670
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 421 KK IPY I FS SATL SN N D SF SFTANS LG VK D Y -- LSFSVA SPF D YEEQ MAV ------ NLLSHTKEN E W - E RKCQ Y TLENIQK 491
Cdd:PRK08074 671 KK KSV I LT SATL TV N G SF DYIIER LG LE D F yp RTLQIP SPF S YEEQ AKL miptdm PPIKDVPIE E Y i E EVAA Y IAKIAKA 750
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 492 T N GR T LVLF RTTQE L AAFKEYVSK E QMSVPFLYEG d Q EI S Q ----- L VSR FQ NEEETV L CAV - HL WEG L DIPG SS LS HVI 565
Cdd:PRK08074 751 T K GR M LVLF TSYEM L KKTYYNLKN E EELEGYVLLA - Q GV S S gsrar L TKQ FQ QFDKAI L LGT s SF WEG I DIPG DE LS CLV 829
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446415829 566 I WS LPF - PP ND PV F EAK ---- RKHVND PF WDVDV P YMI LR LR QG I GRLIRT SD D K G AISIF 621
Cdd:PRK08074 830 I VR LPF a PP DQ PV M EAK sewa KEQGEN PF QELSL P QAV LR FK QG F GRLIRT ET D R G TVFVL 890
dinG_rel
TIGR01407 DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ...
35-621
4.42e-46
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain]
Cd Length: 850
Bit Score: 175.38
E-value: 4.42e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 35 EK G F E E R D EQ IFM A FQLERAFQEKKVMFA EA GV G N GKT IV YLL Y A IC YA R y T G KP AI I ACADET L IE QL V ke E G DI AK L S 114
Cdd:TIGR01407 241 RL G L E Y R P EQ LKL A ELVLDQLTHSEKSLI EA PT G T GKT LG YLL P A LY YA I - T E KP VV I STNTKV L QS QL L -- E K DI PL L N 317
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 115 E A L GLSVDVR L A K SMD NYL C L R K LEDVMSGRAP eviedvyyelp QFV F DHGT MQ NF ----- T HY GD RK E FP L LN deewsk 189
Cdd:TIGR01407 318 E I L NFKINAA L I K GKS NYL S L G K FSQILKDNTD ----------- NYE F NIFK MQ VL vwlte T ET GD LD E LN L KG ------ 380
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 190 V N WDY F QDCFTCDSRHRCGQTLSREH Y RK A ------ A DLI I CSQD fymd HIW T YDARKR E gqip L L P ESSCVVF DE G H LV 263
Cdd:TIGR01407 381 G N KMF F AQVRHDGNLSKKDLFYEVDF Y NR A qknaeq A QIL I TNHA ---- YLI T RLVDNP E ---- L F P SFRDLII DE A H HL 452
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 264 EYA A QKA L TYR L KQTMMEQLLTRLLQND ireefahlveetiwq T E RFFDVL Q EN - K K EI agsdr LE ITVTEKVTAEA K R L 342
Cdd:TIGR01407 453 PDI A ENQ L QEE L DYADIKYQIDLIGKGE --------------- N E QLLKRI Q QL e K Q EI ----- LE KLFDFETKDIL K D L 512
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 343 Y A KIGEVGDA L VFE SE MHTVNTYD L NIV D EH L DVLEHSLRLFMH E KNVITWGE E GDGAFT --- L V I MPRA V EE VL QEKVF 419
Cdd:TIGR01407 513 Q A ILDKLNKL L QIF SE LSHKTVDQ L RKF D LA L KDDFKNIEQSLK E GHTSWISI E NLQQKS tir L Y I KDYE V GD VL TKRLL 592
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 420 S K KIPY IF S SATL SNND SF SFTANS LG VK D YLSFSVA - S P FD Y E E QMA V NLLS ------ HTKEN E WERKCQYTLEN I QK - 491
Cdd:TIGR01407 593 P K FKSL IF T SATL KFSH SF ESFPQL LG LT D VHFNTIE p T P LN Y A E NQR V LIPT dapaiq NKSLE E YAQEIASYIIE I TA i 672
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 492 T NGRT LVLF RTTQE L AAFKEYVSKEQMSVPFLYEG d Q E I S ---- QLVS RF Q N E E ETV L C - AVHL WEG L D I PG SS L SHVI I 566
Cdd:TIGR01407 673 T SPKI LVLF TSYEM L HMVYDMLNELPEFEGYEVLA - Q G I N gsra KIKK RF N N G E KAI L L g TSSF WEG V D F PG NG L VCLV I 751
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 567 WS LPF - P P ND P VFEAKRKHVN ---- D PF W D VDV P YM I L RLRQ GI GRLIR TSD D K G A I S I F 621
Cdd:TIGR01407 752 PR LPF a N P KH P LTKKYWQKLE qegk N PF Y D YVL P MA I I RLRQ AL GRLIR REN D R G S I V I L 811
Helicase_C_2
pfam13307 Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
489-621
1.12e-36
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain]
Cd Length: 168
Bit Score: 135.00
E-value: 1.12e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 489 IQKTN G RT LV L F RTTQE L AAFK E YVSKEQMSVPF -- LYE - G DQEISQ L VSR F QNEEET - VL CA V --- HLW EG L D I PG SS L 561
Cdd:pfam13307 4 LKVIP G GV LV F F PSYSY L EKVA E RLKESGLEKGI ei FVQ p G EGSREK L LEE F KKKGKG a VL FG V cgg SFS EG I D F PG DL L 83
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446415829 562 SH VII WS LPFP - P N DPV F EAKR KHVN ---- D PF WDVDV P YMILRLR Q G IGRLIR TSD D K GAI SIF 621
Cdd:pfam13307 84 RA VII VG LPFP n P D DPV V EAKR EYLD skgg N PF NEWYL P QAVRAVN Q A IGRLIR HEN D Y GAI VLL 148
HELICc2
smart00491 helicase superfamily c-terminal domain;
516-620
2.99e-14
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain]
Cd Length: 142
Bit Score: 70.00
E-value: 2.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 516 EQMSV P FLY EG D -- Q E ISQ L VSRF --- QNEEETV L C AV --- HLW EG L D I P GSSLSH VII WSL PFP - P ND P VFE A KRKHVN 586
Cdd:smart00491 17 LEINK P VFI EG K ds G E TEE L LEKY saa CEARGAL L L AV arg KVS EG I D F P DDLGRA VII VGI PFP n P DS P ILR A RLEYLD 96
90 100 110
....*....|....*....|....*....|....*....
gi 446415829 587 D ----- PF WD V DVPYMILR L R Q G IGR L IR TSD D K G AISI 620
Cdd:smart00491 97 E kggir PF DE V YLFDAMRA L A Q A IGR A IR HKN D Y G VVVL 135
Csf4_U
cd09708 CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly ...
43-624
1.67e-05
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DinG family DNA helicase
Pssm-ID: 187839 [Multi-domain]
Cd Length: 632
Bit Score: 48.05
E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 43 EQ IFMAFQLERAFQE K KVMFA EA GV G N GKT IVYLLY A ICYAR - YTGKPAI IA CADET L IE QL VK E EGDIA kl S E A L GLS V 121
Cdd:cd09708 1 EQ ALFYRNCLTSLRQ K RIGML EA ST G V GKT LAMIMA A LTMLK e RPDQKIA IA VPTLA L MG QL WS E LERLT -- A E G L AGP V 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 122 DVRLAKSMDNYLCLRK L EDVMS grapevi EDVYYELPQF V FDHGTM Q N fthy G D RK EF PL L N D ------- EEWSKVNWD Y 194
Cdd:cd09708 79 QAGFFPGSQEFVSPGA L QELLD ------- QSDGPGDKDA V VRLWMG Q G ---- G P RK VA PL F N R mrdvtll IHDTADIRG Y 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 195 FQDCFTC DS RH RC GQTL ------- S RE H YR KA AD l IICS QDF YM ---- D HI W T -------- Y D ARK R -------- EGQIP 247
Cdd:cd09708 148 VSYREQW DS LP RC SAMS raptkma S MT H DL KA LA - TLNP QDF VT edee D KR W V tslvesre Y Y ARK S rilactht MLKWG 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 248 LLP ESSCVVF DE G HL V E YAAQKALT yrlkqtmm EQ L LT R L L QNDIREEFAHLVEETIWQTERFFD V LQENKKEI A GS D RL 327
Cdd:cd09708 227 LLP QPDILIV DE A HL F E QNISRVYS -------- NA L SL R M L RFHLEVSHRKTGAIGSAVVAAVSA V SHRLRQVS A LG D GQ 298
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 328 EITVTEK v TA E AKR L Y A KIGEVGDALVFESEMHTVNTY D LNIVDEH LD V leh SLRLFMHEKNVITWGEEG D GA F TLV I MP 407
Cdd:cd09708 299 TLCLDAG - NK E LET L F A DLDAALEIKSTPNKKALSVVK D VKKARII LD N --- AITAIQGKQSTVYLQFSP D RR F PSL I VG 374
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 408 R - AVEE V LQEKVFSKKIPY I FS SATL SNN D S F SFTAN slgvk DYL SFSVAS P FDYEEQMA ------- V NL LS H ------- 472
Cdd:cd09708 375 R e DLGK V MGGLWKDVTHGA I IV SATL YLP D R F GQMSC ----- DYL KRVLSL P LSRLDTPS pivapwv R NL IP H lhvpnak 449
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 473 ----------- T KENE ----- W - E RKCQY T LENIQ K TN G R TLVL --- F RTTQELAAFK E Y vske QMSVPFLYE - GDQEIS 531
Cdd:cd09708 450 arfllsrpvgk T EQGD anlag W l E NVSLS T AAILR K AQ G G TLVL tta F SHISAIGQLV E L ---- GIPAEIVIQ s EKNRLA 525
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 532 QLVSR F ---- Q N EEET VL C A VH - L W E G L D IPGS S -------- L SHV II WSL PF PP N DPVFEA KR - KHVNDPFWDVDVP ym 597
Cdd:cd09708 526 SAEQQ F laly A N GIQP VL I A AG g A W T G I D LHDP S vspdkdnl L TDL II TCA PF GL N RSLSML KR i RKTSVRPEIINES -- 603
650 660
....*....|....*....|....*..
gi 446415829 598 ILR LRQG I GRL I R TS D DKGAIS I FLS D 624
Cdd:cd09708 604 LMM LRQG L GRL V R HP D MPINRR I HDL D 630
Name
Accession
Description
Interval
E-value
DinG
COG1199 Rad3-related DNA helicase DinG [Replication, recombination and repair];
36-621
7.03e-158
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain]
Cd Length: 629
Bit Score: 468.25
E-value: 7.03e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 36 K GFE E R DE Q IF MA FQLE RA FQ E KKVMFA EAG V G N GKT IV YL LY A ICY AR Y TGK PAI I AC A DET L I EQLV KE eg D IAK L SE 115
Cdd:COG1199 11 P GFE P R PG Q RE MA EAVA RA LA E GRHLLI EAG T G T GKT LA YL VP A LLA AR E TGK KVV I ST A TKA L Q EQLV EK -- D LPL L RK 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 116 ALGL SVD V R L A K SMD NYLCLR K LE DVMSGRAPEVI E DVYYELPQ fvfdhg TMQNF T HY GDR K E F PL - LN DE E W SK V NW D Y 194
Cdd:COG1199 89 ALGL PLR V A L L K GRS NYLCLR R LE QALQEGDDLDD E ELLLARIL ------ AWASE T WT GDR D E L PL p ED DE L W RQ V TS D A 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 195 FQ d C F -- T C DSRHR C GQT L S R EHY R K a AD LIICSQDFYMDHIWTYD arkregqi P LLPE SSCVVF DE G H LVEYA A QKALT 272
Cdd:COG1199 163 DN - C L gr R C PYYGV C PYE L A R RLA R E - AD VVVVNHHLLFADLALGE -------- E LLPE DDVLII DE A H NLPDR A RDMFS 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 273 YR L KQTMMEQ LL TR L LQNDI R EEFAH L --- V E ETIWQTERF F DV L Q E NKKEIAGSDR L E i TVT E KVTAEAKR L YAKIGEV 349
Cdd:COG1199 233 AE L SSRSLLR LL RE L RKLGL R PGLKK L ldl L E RLREALDDL F LA L E E EEELRLALGE L P - DEP E ELLEALDA L RDALEAL 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 350 GD AL vfes E MHTVNTYD L NIVD E H L DV L EHS L RL F --- MHEKNVIT W G E EGD G AFT L VIM P RAVEEV L Q E KV FS KKIPYI 426
Cdd:COG1199 312 AE AL ---- E EELERLAE L DALL E R L EE L LFA L AR F lri AEDEGYVR W L E REG G DVR L HAA P LDPADL L R E LL FS RARSVV 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 427 FS SATLS NNDS F SFT A NS LG V - K D YLSF S VA SPFDYE E Q M --- AVNL L SHTKENE -- W E RKCQYTL E NIQKTN G R TLVLF 500
Cdd:COG1199 388 LT SATLS VGGP F DYF A RR LG L d E D ARTL S LP SPFDYE N Q A lly VPRD L PRPSDRD gy L E AIAEAIA E LLEASG G N TLVLF 467
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 501 RTTQE L AAFK E YV s K E QMSV P F L YE GD QEISQ L VS RF QNEEET VL CAV - HL WEG L D I PG SS LS H VII WS LPFP - P N DPV F 578
Cdd:COG1199 468 TSYRA L EQVA E LL - R E RLDI P V L VQ GD GSREA L LE RF REGGNS VL VGT g SF WEG V D L PG DA LS L VII VK LPFP p P D DPV L 546
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 446415829 579 EA K R KHVN ---- DP F WDVDV P YMILR L R QG I GRLIR TSD D K G AISIF 621
Cdd:COG1199 547 EA R R EALE argg NG F MYAYL P PAVIK L K QG A GRLIR SEE D R G VVVLL 593
PRK08074
PRK08074 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
18-621
7.66e-62
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain]
Cd Length: 928
Bit Score: 221.36
E-value: 7.66e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 18 Y D KLN E WIGDVFYDIL P ek GF E E R DE Q IF M AFQLER A FQEKKVMFA EAG V G N GK TIV YLL Y A ICY A RYTGK P AI I ACADE 97
Cdd:PRK08074 238 F D AFL E KTEEKLSLAM P -- KY E K R EG Q QE M MKEVYT A LRDSEHALI EAG T G T GK SLA YLL P A AYF A KKKEE P VV I STYTI 315
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 98 T L IE QL V ke E G DI AK L SEALGLS V DVR L A K SMDN YLCLRK L E DVMS grapev I ED VY Y E ----------- L PQ fvfdhgt 166
Cdd:PRK08074 316 Q L QQ QL L -- E K DI PL L QKIFPFP V EAA L L K GRSH YLCLRK F E QALQ ------ E ED DN Y D valtkaqllvw L TE ------- 380
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 167 mqnf T HY GD RK E ---------- FPLLNDEEW S KV ---- N W dy F QD CF TCDSRH R C gqtlsrehyr K A ADL I I CSQDFYM d 232
Cdd:PRK08074 381 ---- T ET GD LD E lnlpsggkll WNRIASDGE S DG gkqs P W -- F SR CF YQRAKN R A ---------- K F ADL V I TNHALLL - 443
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 233 HIW T YDA rkregqi PLLP ESSCVVF DE G H LV E Y AA Q ------------ KA L TY RL KQTMMEQ LL TR L LQ ----------- 289
Cdd:PRK08074 444 TDL T SEE ------- PLLP SYEHIII DE A H HF E E AA S rhlgeqfsymsf QL L LS RL GTLEEDG LL SK L AK lfkksdqasrs 516
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 290 -- N D IR E EFAH L VE E T iwqt ERF F DV L Q ------- ENKKEIAGSD R LE ------------ ITVTEKVTAEAKR L YAKIGE 348
Cdd:PRK08074 517 sf R D LD E SLKE L KF E A ---- DEL F QM L R sfvlkrk KQEQNGRLIY R YN tesekgklwdai TELANRLCYDLRD L LTLLEA 592
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 349 VGDA L -- VF ESE MHTV n T YDLNIVDEH L DVLEHS L R L f MH E K -- NVI TW G E - EGD GA FTLVIM --- P RA V E E V L QEKV F S 420
Cdd:PRK08074 593 QKKE L qe KM ESE SAFL - T GEYAHLIDL L EKMAQL L Q L - LF E E dp DYV TW I E i DAK GA INATRL yaq P VE V A E R L ADEF F A 670
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 421 KK IPY I FS SATL SN N D SF SFTANS LG VK D Y -- LSFSVA SPF D YEEQ MAV ------ NLLSHTKEN E W - E RKCQ Y TLENIQK 491
Cdd:PRK08074 671 KK KSV I LT SATL TV N G SF DYIIER LG LE D F yp RTLQIP SPF S YEEQ AKL miptdm PPIKDVPIE E Y i E EVAA Y IAKIAKA 750
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 492 T N GR T LVLF RTTQE L AAFKEYVSK E QMSVPFLYEG d Q EI S Q ----- L VSR FQ NEEETV L CAV - HL WEG L DIPG SS LS HVI 565
Cdd:PRK08074 751 T K GR M LVLF TSYEM L KKTYYNLKN E EELEGYVLLA - Q GV S S gsrar L TKQ FQ QFDKAI L LGT s SF WEG I DIPG DE LS CLV 829
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446415829 566 I WS LPF - PP ND PV F EAK ---- RKHVND PF WDVDV P YMI LR LR QG I GRLIRT SD D K G AISIF 621
Cdd:PRK08074 830 I VR LPF a PP DQ PV M EAK sewa KEQGEN PF QELSL P QAV LR FK QG F GRLIRT ET D R G TVFVL 890
dinG_rel
TIGR01407 DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ...
35-621
4.42e-46
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain]
Cd Length: 850
Bit Score: 175.38
E-value: 4.42e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 35 EK G F E E R D EQ IFM A FQLERAFQEKKVMFA EA GV G N GKT IV YLL Y A IC YA R y T G KP AI I ACADET L IE QL V ke E G DI AK L S 114
Cdd:TIGR01407 241 RL G L E Y R P EQ LKL A ELVLDQLTHSEKSLI EA PT G T GKT LG YLL P A LY YA I - T E KP VV I STNTKV L QS QL L -- E K DI PL L N 317
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 115 E A L GLSVDVR L A K SMD NYL C L R K LEDVMSGRAP eviedvyyelp QFV F DHGT MQ NF ----- T HY GD RK E FP L LN deewsk 189
Cdd:TIGR01407 318 E I L NFKINAA L I K GKS NYL S L G K FSQILKDNTD ----------- NYE F NIFK MQ VL vwlte T ET GD LD E LN L KG ------ 380
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 190 V N WDY F QDCFTCDSRHRCGQTLSREH Y RK A ------ A DLI I CSQD fymd HIW T YDARKR E gqip L L P ESSCVVF DE G H LV 263
Cdd:TIGR01407 381 G N KMF F AQVRHDGNLSKKDLFYEVDF Y NR A qknaeq A QIL I TNHA ---- YLI T RLVDNP E ---- L F P SFRDLII DE A H HL 452
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 264 EYA A QKA L TYR L KQTMMEQLLTRLLQND ireefahlveetiwq T E RFFDVL Q EN - K K EI agsdr LE ITVTEKVTAEA K R L 342
Cdd:TIGR01407 453 PDI A ENQ L QEE L DYADIKYQIDLIGKGE --------------- N E QLLKRI Q QL e K Q EI ----- LE KLFDFETKDIL K D L 512
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 343 Y A KIGEVGDA L VFE SE MHTVNTYD L NIV D EH L DVLEHSLRLFMH E KNVITWGE E GDGAFT --- L V I MPRA V EE VL QEKVF 419
Cdd:TIGR01407 513 Q A ILDKLNKL L QIF SE LSHKTVDQ L RKF D LA L KDDFKNIEQSLK E GHTSWISI E NLQQKS tir L Y I KDYE V GD VL TKRLL 592
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 420 S K KIPY IF S SATL SNND SF SFTANS LG VK D YLSFSVA - S P FD Y E E QMA V NLLS ------ HTKEN E WERKCQYTLEN I QK - 491
Cdd:TIGR01407 593 P K FKSL IF T SATL KFSH SF ESFPQL LG LT D VHFNTIE p T P LN Y A E NQR V LIPT dapaiq NKSLE E YAQEIASYIIE I TA i 672
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 492 T NGRT LVLF RTTQE L AAFKEYVSKEQMSVPFLYEG d Q E I S ---- QLVS RF Q N E E ETV L C - AVHL WEG L D I PG SS L SHVI I 566
Cdd:TIGR01407 673 T SPKI LVLF TSYEM L HMVYDMLNELPEFEGYEVLA - Q G I N gsra KIKK RF N N G E KAI L L g TSSF WEG V D F PG NG L VCLV I 751
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 567 WS LPF - P P ND P VFEAKRKHVN ---- D PF W D VDV P YM I L RLRQ GI GRLIR TSD D K G A I S I F 621
Cdd:TIGR01407 752 PR LPF a N P KH P LTKKYWQKLE qegk N PF Y D YVL P MA I I RLRQ AL GRLIR REN D R G S I V I L 811
dinG
PRK11747 ATP-dependent DNA helicase DinG; Provisional
30-621
3.18e-38
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain]
Cd Length: 697
Bit Score: 150.75
E-value: 3.18e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 30 Y DI L P E -- K GF EE R DE Q IF M AFQLERAF ----- QEKKVMFA EAG V G N GKT IV YLL YA I CY AR YTG K PAI I AC A DET L I EQ 102
Cdd:PRK11747 14 Y KA L Q E ql P GF IP R AG Q RQ M IAEVAKTL ageyl KDGRILVI EAG T G V GKT LS YLL AG I PI AR AEK K KLV I ST A TVA L Q EQ 93
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 103 LV ke EG D IAK L SEAL GL SVDVR LAK SMDN Y L C L RKL EDVM S GRAPEV iedvyy E L PQ F VF D HG T ------------- MQN 169
Cdd:PRK11747 94 LV -- SK D LPL L LKIS GL DFKFT LAK GRGR Y V C P RKL AALA S DEGTQQ ------ D L LL F LD D EL T ppdeeeqkllarl AKA 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 170 FTHY --- GDR KEF P L - LN D EE W SKVNW D YFQ d C FT -- C DSRHR C GQTLS R EHYRK A a D LIICSQ D FYMD hiwty D ARKRE 243
Cdd:PRK11747 166 LATG kwd GDR DHW P E p ID D SL W QRITT D KHS - C LG rn C PYFRE C PFFKA R REIDE A - D VVVANH D LVLA ----- D LELGG 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 244 G QIPLL PE SSCV V F DEGH lve YAAQK A L ----- TYR LK Q T ----- MMEQ LLT R L ----------------- LQNDI RE -- 294
Cdd:PRK11747 239 G VVLPD PE NLLY V L DEGH --- HLPDV A R dhfaa SAE LK G T adwle KLLK LLT K L valimepplalperlna HCEEL RE ll 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 295 - EFAHLV -------- EE TIW qte RF FD - V L Q E NKK E I A GS drleitv TE K V T AEAKR L YA K IG - EVGD A L vf ESEMHTVN 363
Cdd:PRK11747 316 a SLNQIL nlflpagg EE ARY --- RF EM g E L P E ELL E L A ER ------- LA K L T EKLLG L LE K LL n DLSE A M -- KTGKIDIV 383
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 364 TYD -- L NIVDEH L DV LE -- HS L - RL FM --- H E KNV ----- IT - WGEE G D G AFTLVIM P RA V EEV L QEKVF S KKIPYIFS S 429
Cdd:PRK11747 384 RLE rl L LELGRA L GR LE al SK L w RL AA ked Q E SGA pmarw IT r EERD G Q G DYLFHAS P IR V GDQ L ERLLW S RAPGAVLT S 463
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 430 ATL SNND SF SFTANSL G VKD ----- Y L S fs VA SPFDY EE Q ------- M AV --- N LLS HT K E newer KCQYTL E NIQ K TN G 494
Cdd:PRK11747 464 ATL RSLN SF DRFQEQS G LPE kdgdr F L A -- LP SPFDY PN Q gklvipk M RA epd N EEA HT A E ----- MAEFLP E LLE K HK G 536
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 495 r T LVLF RTTQELAAFKEYVSKE q MSVPF L YE GDQ EISQ L V ---- S R FQNE E ET VL CAVH - LW EGLD I PG SS L SH VII WSL 569
Cdd:PRK11747 537 - S LVLF ASRRQMQKVADLLPRD - LRLML L VQ GDQ PRQR L L ekhk K R VDEG E GS VL FGLQ s FA EGLD L PG DY L TQ VII TKI 614
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 446415829 570 PF - P P ND PV FEA ------ K R KH vn D PF WDVD VP YMILR L R Q GI GRLIR TSD D K G AIS I F 621
Cdd:PRK11747 615 PF a V P DS PV EAT laewlk S R GG -- N PF MEIS VP DASFK L I Q AV GRLIR SEQ D R G RVT I L 671
Helicase_C_2
pfam13307 Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
489-621
1.12e-36
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain]
Cd Length: 168
Bit Score: 135.00
E-value: 1.12e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 489 IQKTN G RT LV L F RTTQE L AAFK E YVSKEQMSVPF -- LYE - G DQEISQ L VSR F QNEEET - VL CA V --- HLW EG L D I PG SS L 561
Cdd:pfam13307 4 LKVIP G GV LV F F PSYSY L EKVA E RLKESGLEKGI ei FVQ p G EGSREK L LEE F KKKGKG a VL FG V cgg SFS EG I D F PG DL L 83
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446415829 562 SH VII WS LPFP - P N DPV F EAKR KHVN ---- D PF WDVDV P YMILRLR Q G IGRLIR TSD D K GAI SIF 621
Cdd:pfam13307 84 RA VII VG LPFP n P D DPV V EAKR EYLD skgg N PF NEWYL P QAVRAVN Q A IGRLIR HEN D Y GAI VLL 148
HELICc2
smart00491 helicase superfamily c-terminal domain;
516-620
2.99e-14
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain]
Cd Length: 142
Bit Score: 70.00
E-value: 2.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 516 EQMSV P FLY EG D -- Q E ISQ L VSRF --- QNEEETV L C AV --- HLW EG L D I P GSSLSH VII WSL PFP - P ND P VFE A KRKHVN 586
Cdd:smart00491 17 LEINK P VFI EG K ds G E TEE L LEKY saa CEARGAL L L AV arg KVS EG I D F P DDLGRA VII VGI PFP n P DS P ILR A RLEYLD 96
90 100 110
....*....|....*....|....*....|....*....
gi 446415829 587 D ----- PF WD V DVPYMILR L R Q G IGR L IR TSD D K G AISI 620
Cdd:smart00491 97 E kggir PF DE V YLFDAMRA L A Q A IGR A IR HKN D Y G VVVL 135
PRK07246
PRK07246 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
426-620
1.12e-08
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 180905 [Multi-domain]
Cd Length: 820
Bit Score: 58.16
E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 426 I F S SATL SNNDSF S F t A NS LG VKD YL SFSVAS pf D YEEQMA V ------ N L LSH T KENEWERKCQYT LE NIQKTNGRT LVL 499
Cdd:PRK07246 577 Y F V SATL QISPRV S L - A DL LG FEE YL FHKIEK -- D KKQDQL V vvdqdm P L VTE T SDEVYAEEIAKR LE ELKQLQQPI LVL 653
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 500 F RTTQE L A A FKEYV sk E Q MS V PF L - Y E GDQEISQLVS RF QNE E ETV L C - AVHL WEG L D I pg SSLSHV I -- I WS LPF P - P N 574
Cdd:PRK07246 654 F NSKKH L L A VSDLL -- D Q WQ V SH L a Q E KNGTAYNIKK RF DRG E QQI L L g LGSF WEG V D F -- VQADRM I ev I TR LPF D n P E 729
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446415829 575 DP VFEAKRKHVN ---- D PF W D VDV P YM ILRL R Q G IGR LI R TS D D K G A IS I 620
Cdd:PRK07246 730 DP FVKKMNQYLL qegk N PF Y D YFL P MT ILRL K Q A IGR TM R RE D Q K S A VL I 779
Csf4_U
cd09708 CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly ...
43-624
1.67e-05
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DinG family DNA helicase
Pssm-ID: 187839 [Multi-domain]
Cd Length: 632
Bit Score: 48.05
E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 43 EQ IFMAFQLERAFQE K KVMFA EA GV G N GKT IVYLLY A ICYAR - YTGKPAI IA CADET L IE QL VK E EGDIA kl S E A L GLS V 121
Cdd:cd09708 1 EQ ALFYRNCLTSLRQ K RIGML EA ST G V GKT LAMIMA A LTMLK e RPDQKIA IA VPTLA L MG QL WS E LERLT -- A E G L AGP V 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 122 DVRLAKSMDNYLCLRK L EDVMS grapevi EDVYYELPQF V FDHGTM Q N fthy G D RK EF PL L N D ------- EEWSKVNWD Y 194
Cdd:cd09708 79 QAGFFPGSQEFVSPGA L QELLD ------- QSDGPGDKDA V VRLWMG Q G ---- G P RK VA PL F N R mrdvtll IHDTADIRG Y 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 195 FQDCFTC DS RH RC GQTL ------- S RE H YR KA AD l IICS QDF YM ---- D HI W T -------- Y D ARK R -------- EGQIP 247
Cdd:cd09708 148 VSYREQW DS LP RC SAMS raptkma S MT H DL KA LA - TLNP QDF VT edee D KR W V tslvesre Y Y ARK S rilactht MLKWG 226
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 248 LLP ESSCVVF DE G HL V E YAAQKALT yrlkqtmm EQ L LT R L L QNDIREEFAHLVEETIWQTERFFD V LQENKKEI A GS D RL 327
Cdd:cd09708 227 LLP QPDILIV DE A HL F E QNISRVYS -------- NA L SL R M L RFHLEVSHRKTGAIGSAVVAAVSA V SHRLRQVS A LG D GQ 298
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 328 EITVTEK v TA E AKR L Y A KIGEVGDALVFESEMHTVNTY D LNIVDEH LD V leh SLRLFMHEKNVITWGEEG D GA F TLV I MP 407
Cdd:cd09708 299 TLCLDAG - NK E LET L F A DLDAALEIKSTPNKKALSVVK D VKKARII LD N --- AITAIQGKQSTVYLQFSP D RR F PSL I VG 374
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 408 R - AVEE V LQEKVFSKKIPY I FS SATL SNN D S F SFTAN slgvk DYL SFSVAS P FDYEEQMA ------- V NL LS H ------- 472
Cdd:cd09708 375 R e DLGK V MGGLWKDVTHGA I IV SATL YLP D R F GQMSC ----- DYL KRVLSL P LSRLDTPS pivapwv R NL IP H lhvpnak 449
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 473 ----------- T KENE ----- W - E RKCQY T LENIQ K TN G R TLVL --- F RTTQELAAFK E Y vske QMSVPFLYE - GDQEIS 531
Cdd:cd09708 450 arfllsrpvgk T EQGD anlag W l E NVSLS T AAILR K AQ G G TLVL tta F SHISAIGQLV E L ---- GIPAEIVIQ s EKNRLA 525
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 532 QLVSR F ---- Q N EEET VL C A VH - L W E G L D IPGS S -------- L SHV II WSL PF PP N DPVFEA KR - KHVNDPFWDVDVP ym 597
Cdd:cd09708 526 SAEQQ F laly A N GIQP VL I A AG g A W T G I D LHDP S vspdkdnl L TDL II TCA PF GL N RSLSML KR i RKTSVRPEIINES -- 603
650 660
....*....|....*....|....*..
gi 446415829 598 ILR LRQG I GRL I R TS D DKGAIS I FLS D 624
Cdd:cd09708 604 LMM LRQG L GRL V R HP D MPINRR I HDL D 630
SF2_C_XPD
cd18788 C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ...
552-622
2.55e-04
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain]
Cd Length: 159
Bit Score: 41.82
E-value: 2.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446415829 552 EG L D IPGSSLSH VI IWSL P F P P - N DP VFEA K RKH --------- VNDPF W dvdvp Y MILRL R --- Q G IGR L IR TSD D K GAI 618
Cdd:cd18788 78 EG I D FSDDLGRA VI MVGI P Y P N t K DP ILKL K MDD leylrdkgl LTGED W ----- Y TFQAM R avn Q A IGR A IR HKN D Y GAI 152
....
gi 446415829 619 s IF L 622
Cdd:cd18788 153 - VL L 155
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
