|
Name |
Accession |
Description |
Interval |
E-value |
| pheT |
PRK00629 |
phenylalanyl-tRNA synthetase subunit beta; Reviewed |
1-806 |
0e+00 |
|
phenylalanyl-tRNA synthetase subunit beta; Reviewed
Pssm-ID: 234804 [Multi-domain] Cd Length: 791 Bit Score: 1094.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 1 MFVSYRWLQEYVDIkDVTAQELADKITKSGIEVEGVEVLNKGVKGVVVGHVLECEKHPEADKLSKCLIDIGEEEpVQIIC 80
Cdd:PRK00629 1 MKFSLSWLKEYVNP-DISSEELAEALTMIGLEVEGVEDVAAGLSGVVVGKVLECEKHPNADKLRVCQVDVGEEP-LQIVC 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 81 GAANIAKGLKVPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIDgklvskEYADGIFIFPSDAEVGADALEILNL 160
Cdd:PRK00629 79 GAPNVRAGDKVPVALPGAVLPGGFKIKKAKLRGVESEGMLCSASELGLS------DDHDGIIELPEDAPVGTDAREYLGL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 161 HDEVLELGLTPNRADCLNMLGVAYEVAAIYGREVKLPAIdlQETAEKTSDYISVSVEAKEENPLYIAKMVKNVK-IGPSP 239
Cdd:PRK00629 153 DDTVIEISLTPNRADCLSVRGIARELAALLGLPLKLPEI--EPVPATIDDKLPVEIEDPDLCPRYAGRVIKGVKnIAPSP 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 240 MWMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLGsKEIVVRLAKEGEKIETLDDQERTLQSHHLVITNGTKA 319
Cdd:PRK00629 231 LWLQERLRAAGIRPINNVVDITNYVMLELGQPLHAFDLDKIG-GGIVVRRAKEGEKLTTLDGKERTLDPEDLVIADDKKP 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 320 LAVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEAIQHAAALMAKYAGGEALE 399
Cdd:PRK00629 310 LALAGVMGGEDSEVTENTTNVLLESAYFDPVSIRKTARRLGLRTDASYRFERGVDPALTLLALERATALILELGGGEVVE 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 400 GVVEADNLQiQERTVSVTAEKVNRVLGTNISASEMGTMFANLKFPFTEV-EGTFHVNVPARRPDITISEDLVEEVGRLYG 478
Cdd:PRK00629 390 GVVDVYPLP-KEPTITLRLERINRLLGTEISDEEIVDILKRLGFEVTEVdGDGLTVTVPSWRFDIEIEEDLVEEVARIYG 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 479 YDHIPVTLPSGTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYMIEPNekaPVNLALPMSEERSQLRLS 558
Cdd:PRK00629 469 YDNIPSTPPVAALTMGGLTEAQRLLRRLRRALAALGYQEVITYSFVSPEDAKLFGLNPE---PLLLLNPISEELSVMRTS 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 559 LVPQLLEAVSYNIARKNDSVALYEVGSIFLPTEagELPKEEQHLAGVMTGLALHHAWQGEKKvVDFFVVKGVLEGLFDVL 638
Cdd:PRK00629 546 LLPGLLEAVAYNLNRGNKDVALFEIGRVFLPDG--DLPREPEHLAGVLTGNRVEESWGGKRP-VDFFDLKGDVEALLEAL 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 639 GVSNQITYAPAKREGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSLVKIFGADAEETYYSAIPRFPSM 717
Cdd:PRK00629 623 GLPEVEFVAEFEAAALHPGRSAEIYLDGKVIGFIGELHPKVLKKLDLPGrTYVFELDLDALLEAARKLPKYKPISKFPAV 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 718 TRDMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKKSLAFSMTYFDAERTLTDEEVTEAHNRVLTTVE 797
Cdd:PRK00629 703 RRDLALVVDEDVPAADILKAIKKAGGKLLESVELFDVYEGKGIGEGKKSLAFRLTFQDPDRTLTDEEINAAMDKIVAALE 782
|
....*....
gi 446420323 798 EKFGAELRK 806
Cdd:PRK00629 783 EKFGAELRG 791
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
1-806 |
0e+00 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 1050.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 1 MFVSYRWLQEYVDIKDVTAQELADKITkSGIEVEGVEVLNKGVKGVVVGHVLECEKHPEADKLSKCLIDIGEEEPVQIIC 80
Cdd:COG0072 1 MKLSLLWLLLLVEEAALLEELLLLLTG-EGLEEEEVEGAAAVVVGVVVVVVVVEEPHPDADDLVVVVVDVGGGEVLVVVC 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 81 GAANIAKGLKVPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIdgklvsKEYADGIFIFPSDAEVGADALEILNL 160
Cdd:COG0072 80 GAANVAVGVVVVAAPGGAVLPGGFKIKKAKIRGVESSGMLCSEEELGL------GEDHDGIIVLPPDAPVGGDAREYLGL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 161 HDEVLELGLTPNRADCLNMLGVAYEVAAIYGREVKLPAIDLqETAEKTSDYISVSVEAKEENPLYIAKMVKNVKIGPSPM 240
Cdd:COG0072 154 DDTVLEIDLTPNRADCLSVRGVARELAALLGAPLKLPAIEP-EVPPAIDDPIPVEIEDPEACPRYAGRVIRGVKVGPSPL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 241 WMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLGSKeIVVRLAKEGEKIETLDDQERTLQSHHLVITNGTKAL 320
Cdd:COG0072 233 WMQERLRAAGIRPINNVVDITNYVMLELGQPLHAFDLDKLKGG-IVVRRAREGEKLTTLDGKERTLDPDDLVIADDEGPL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 321 AVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEAIQHAAALMAKYAGGEALEG 400
Cdd:COG0072 312 ALAGVMGGEDSEVTEETTDVLLESAYFDPVSIRRTARRLGLHSDASYRFERGVDPALTVAALERATQLILEIAGGEVGPG 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 401 VVEADNLQIQERTVSVTAEKVNRVLGTNISASEMGTMFANLKFPFTEVEGTFHVNVPARRPDITISEDLVEEVGRLYGYD 480
Cdd:COG0072 392 IVDVYPEPPEPKTITLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDGLTVTVPSWRFDIEIEADLIEEVARIYGYD 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 481 HIPVTLPSGTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYMIEPNekaPVNLALPMSEERSQLRLSLV 560
Cdd:COG0072 472 NIPSTLPRAPLAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPEDADLFGLRRE---AVRLANPISEDLSVMRTSLL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 561 PQLLEAVSYNIARKNDSVALYEVGSIFLPtEAGELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGV 640
Cdd:COG0072 549 PGLLEAAAYNLNRGQKDVRLFEIGRVFLP-DEGEEPREPLHLAGVLTGNREPESWGGKARPVDFFDLKGDVEALLAALGV 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 641 SNqITYAPAKREGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSLVKIFGADAEETYYSAIPRFPSMTR 719
Cdd:COG0072 628 PK-LEFEAAEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPGpVYVFELDLDALLELARKVPKYKPISKFPAVRR 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 720 DMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKKSLAFSMTYFDAERTLTDEEVTEAHNRVLTTVEEK 799
Cdd:COG0072 707 DLALVVDEDVPAADVLDAIRKAAGKLLEDVRLFDVYEGKGVPEGKKSLAFSLTLQDPDRTLTDEEIDAAMDKIVAALEKK 786
|
....*..
gi 446420323 800 FGAELRK 806
Cdd:COG0072 787 FGAELRG 793
|
|
| pheT_bact |
TIGR00472 |
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of ... |
1-805 |
0e+00 |
|
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from Bacteria other than spirochetes, as well as a chloroplast-encoded form from Porphyra purpurea. The chloroplast-derived sequence is considerably shorter at the amino end. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273097 [Multi-domain] Cd Length: 797 Bit Score: 849.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 1 MFVSYRWLQEYVDIKDVTAQELADKITKSGIEVEGVEVLNKGVKGVVVGHVLECEKHPEADKLSKCLIDIGEEEPVQIIC 80
Cdd:TIGR00472 1 MKISLKWLREYVPLSEIDNEEIAEALTSIGLEVEAVIPFSKPLKGVVVGKVLEVEPHPNADKLKVCKVDIGEKEMLQIVC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 81 GAANIAKGLKVPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIDGKlvskeyADGIFIFPSDAEVGADALEILNL 160
Cdd:TIGR00472 81 GAPNVEAGKKVAVALPGAKLPNGLKIKKSKLRGVESEGMLCSESELGLDEK------SDGIIVLDEDAPLGTDIAEYLGL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 161 HDEVLELGLTPNRADCLNMLGVAYEVAAIYGREVKLPAIDLQETAEKTSDYISVSVEAKEENPLYIAKMVKNVKIGPSPM 240
Cdd:TIGR00472 155 DDDIIEVSITPNRGDCLSILGIARELAALFDLNLETPVPFEPETTETIDEGFKIEIEDPEVCPFYLGRVIKGVKVKPSPL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 241 WMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLgSKEIVVRLAKEGEKIETLDDQERTLQSHHLVITNGTKAL 320
Cdd:TIGR00472 235 WLKERLRRSGIRPINNIVDITNYVMLELGQPLHAFDADKI-EGNIVVRSAKEGESFTTLDGKERELKKGDLVIADDKKPL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 321 AVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEAIQHAAALMAKYAGGEALEG 400
Cdd:TIGR00472 314 AIAGVMGGKESGVTDTTTNIFLESAYFNPESIRKTARRLGISTDSSYRFERGVDPELTELALDRALNLILEIFGGEVISV 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 401 VVEADNLQIQERTVSVTAEKVNRVLGTNISASEMGTMFANLKFPFTEVEGTFHVNVPARRPDITISEDLVEEVGRLYGYD 480
Cdd:TIGR00472 394 VSDNYKEKAKEKKISLRIKKLNKILGIELSDEEVRDILKRLGFKVEKQKDGWEVTVPSYRHDIEIEEDLIEEIARIYGYD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 481 HIPVTLPSGTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYmIEPNEKAPVNLALPMSEERSQLRLSLV 560
Cdd:TIGR00472 474 NIPAEPLSVSSKLNKNNENYLLLRKLRTLLVGLGLNEVITYSFVDPEKAEKF-NFPKLENLVEIKNPLSNERSVLRTSLL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 561 PQLLEAVSYNIARKNDSVALYEVGSIFlpTEAGELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGV 640
Cdd:TIGR00472 553 PSLLEVLAYNQNRKNKDVKIFEIGKVF--AKDGEAVKEQLRLAILISGEKNPSSWNHKEEKVDFYDLKGDVESLLELLGL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 641 SNQITYAPAKR-EGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSLVKIFGADAEETYYSAIPRFPSMT 718
Cdd:TIGR00472 631 SDDVYFKNTAEnEELHPGQSATIYLKGKKIGFIGELHPEIAKKYDLKEpTFVFELDLDRLLESLKKVPKYRPISKFPAVT 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 719 RDMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKKSLAFSMTYFDAERTLTDEEVTEAHNRVLTTVEE 798
Cdd:TIGR00472 711 RDISFLVPKDVPANEIIKLIKKSGLELLEEVELFDVYQGKNIGEGKKSLALRLVLRDKERTLTDEEINKIVEKVLNALKE 790
|
....*..
gi 446420323 799 KFGAELR 805
Cdd:TIGR00472 791 KLGAELR 797
|
|
| tRNA_synthFbeta |
pfam17759 |
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ... |
482-695 |
2.17e-93 |
|
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.
Pssm-ID: 465487 [Multi-domain] Cd Length: 214 Bit Score: 290.99 E-value: 2.17e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 482 IPVTLPSGTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYMIEPNEKAPVNLALPMSEERSQLRLSLVP 561
Cdd:pfam17759 1 IPSTLPKGPTTGGGLTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKDLDKLLEDDPRRKAVKLANPLSEELSVMRTSLLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 562 QLLEAVSYNIARKNDSVALYEVGSIFLPTEAGELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGVS 641
Cdd:pfam17759 81 GLLETLAYNLNRGNPDVRLFEIGRVFLPDELEELPREPRRLAGLLTGKRLPESWQGKARPVDFYDLKGIVEALLAALGID 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446420323 642 NqITYAPAKREGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSL 695
Cdd:pfam17759 161 D-YEFEAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPQpVYVFELDL 214
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
223-394 |
3.45e-74 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 239.08 E-value: 3.45e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 223 PLYIAKMVKNVKIG-PSPMWMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLGSKEIVVRLAKEGEKIETLDD 301
Cdd:smart00873 2 PRYLGRVIRGVKNTrPSPEWLQERLHRAGIRPINNVVDITNYVSLETGQPLHAFDLDKIKGKDIPLRRAKEGEKFETLDG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 302 QERTLQSHHLVITNGTKALAVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEA 381
Cdd:smart00873 82 KEYELDEGDLVIADDEGPLALAGVMGGEESEVTENTTVIFLEPAIFSPRTIRITARTLNLFTDASGRFERGVDPELVELA 161
|
170
....*....|...
gi 446420323 382 IQHAAALMAKYAG 394
Cdd:smart00873 162 LDRAAALLLEICG 174
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
498-695 |
1.42e-69 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 227.53 E-value: 1.42e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 498 SAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYMIEPNEkaPVNLALPMSEERSQLRLSLVPQLLEAVSYNIARKNDS 577
Cdd:cd00769 1 PLQKLERKLRRLLAGLGFQEVITYSLTSPEEAELFDGGLDE--AVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKNKP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 578 VALYEVGSIFLPTEagELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGVSNQITYAPAKREGMHPG 657
Cdd:cd00769 79 LRLFEIGRVFLKDE--DGPEEEEHLAALLSGNREPESWQGKGRPVDFYDAKGILEALLRALGIIVEFELEELDADLFHPG 156
|
170 180 190
....*....|....*....|....*....|....*....
gi 446420323 658 RTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSL 695
Cdd:cd00769 157 RSAKIYVNGEVIGFIGELHPEVLKEFDLKEpVYAFELDL 195
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pheT |
PRK00629 |
phenylalanyl-tRNA synthetase subunit beta; Reviewed |
1-806 |
0e+00 |
|
phenylalanyl-tRNA synthetase subunit beta; Reviewed
Pssm-ID: 234804 [Multi-domain] Cd Length: 791 Bit Score: 1094.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 1 MFVSYRWLQEYVDIkDVTAQELADKITKSGIEVEGVEVLNKGVKGVVVGHVLECEKHPEADKLSKCLIDIGEEEpVQIIC 80
Cdd:PRK00629 1 MKFSLSWLKEYVNP-DISSEELAEALTMIGLEVEGVEDVAAGLSGVVVGKVLECEKHPNADKLRVCQVDVGEEP-LQIVC 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 81 GAANIAKGLKVPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIDgklvskEYADGIFIFPSDAEVGADALEILNL 160
Cdd:PRK00629 79 GAPNVRAGDKVPVALPGAVLPGGFKIKKAKLRGVESEGMLCSASELGLS------DDHDGIIELPEDAPVGTDAREYLGL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 161 HDEVLELGLTPNRADCLNMLGVAYEVAAIYGREVKLPAIdlQETAEKTSDYISVSVEAKEENPLYIAKMVKNVK-IGPSP 239
Cdd:PRK00629 153 DDTVIEISLTPNRADCLSVRGIARELAALLGLPLKLPEI--EPVPATIDDKLPVEIEDPDLCPRYAGRVIKGVKnIAPSP 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 240 MWMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLGsKEIVVRLAKEGEKIETLDDQERTLQSHHLVITNGTKA 319
Cdd:PRK00629 231 LWLQERLRAAGIRPINNVVDITNYVMLELGQPLHAFDLDKIG-GGIVVRRAKEGEKLTTLDGKERTLDPEDLVIADDKKP 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 320 LAVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEAIQHAAALMAKYAGGEALE 399
Cdd:PRK00629 310 LALAGVMGGEDSEVTENTTNVLLESAYFDPVSIRKTARRLGLRTDASYRFERGVDPALTLLALERATALILELGGGEVVE 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 400 GVVEADNLQiQERTVSVTAEKVNRVLGTNISASEMGTMFANLKFPFTEV-EGTFHVNVPARRPDITISEDLVEEVGRLYG 478
Cdd:PRK00629 390 GVVDVYPLP-KEPTITLRLERINRLLGTEISDEEIVDILKRLGFEVTEVdGDGLTVTVPSWRFDIEIEEDLVEEVARIYG 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 479 YDHIPVTLPSGTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYMIEPNekaPVNLALPMSEERSQLRLS 558
Cdd:PRK00629 469 YDNIPSTPPVAALTMGGLTEAQRLLRRLRRALAALGYQEVITYSFVSPEDAKLFGLNPE---PLLLLNPISEELSVMRTS 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 559 LVPQLLEAVSYNIARKNDSVALYEVGSIFLPTEagELPKEEQHLAGVMTGLALHHAWQGEKKvVDFFVVKGVLEGLFDVL 638
Cdd:PRK00629 546 LLPGLLEAVAYNLNRGNKDVALFEIGRVFLPDG--DLPREPEHLAGVLTGNRVEESWGGKRP-VDFFDLKGDVEALLEAL 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 639 GVSNQITYAPAKREGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSLVKIFGADAEETYYSAIPRFPSM 717
Cdd:PRK00629 623 GLPEVEFVAEFEAAALHPGRSAEIYLDGKVIGFIGELHPKVLKKLDLPGrTYVFELDLDALLEAARKLPKYKPISKFPAV 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 718 TRDMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKKSLAFSMTYFDAERTLTDEEVTEAHNRVLTTVE 797
Cdd:PRK00629 703 RRDLALVVDEDVPAADILKAIKKAGGKLLESVELFDVYEGKGIGEGKKSLAFRLTFQDPDRTLTDEEINAAMDKIVAALE 782
|
....*....
gi 446420323 798 EKFGAELRK 806
Cdd:PRK00629 783 EKFGAELRG 791
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
1-806 |
0e+00 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 1050.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 1 MFVSYRWLQEYVDIKDVTAQELADKITkSGIEVEGVEVLNKGVKGVVVGHVLECEKHPEADKLSKCLIDIGEEEPVQIIC 80
Cdd:COG0072 1 MKLSLLWLLLLVEEAALLEELLLLLTG-EGLEEEEVEGAAAVVVGVVVVVVVVEEPHPDADDLVVVVVDVGGGEVLVVVC 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 81 GAANIAKGLKVPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIdgklvsKEYADGIFIFPSDAEVGADALEILNL 160
Cdd:COG0072 80 GAANVAVGVVVVAAPGGAVLPGGFKIKKAKIRGVESSGMLCSEEELGL------GEDHDGIIVLPPDAPVGGDAREYLGL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 161 HDEVLELGLTPNRADCLNMLGVAYEVAAIYGREVKLPAIDLqETAEKTSDYISVSVEAKEENPLYIAKMVKNVKIGPSPM 240
Cdd:COG0072 154 DDTVLEIDLTPNRADCLSVRGVARELAALLGAPLKLPAIEP-EVPPAIDDPIPVEIEDPEACPRYAGRVIRGVKVGPSPL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 241 WMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLGSKeIVVRLAKEGEKIETLDDQERTLQSHHLVITNGTKAL 320
Cdd:COG0072 233 WMQERLRAAGIRPINNVVDITNYVMLELGQPLHAFDLDKLKGG-IVVRRAREGEKLTTLDGKERTLDPDDLVIADDEGPL 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 321 AVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEAIQHAAALMAKYAGGEALEG 400
Cdd:COG0072 312 ALAGVMGGEDSEVTEETTDVLLESAYFDPVSIRRTARRLGLHSDASYRFERGVDPALTVAALERATQLILEIAGGEVGPG 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 401 VVEADNLQIQERTVSVTAEKVNRVLGTNISASEMGTMFANLKFPFTEVEGTFHVNVPARRPDITISEDLVEEVGRLYGYD 480
Cdd:COG0072 392 IVDVYPEPPEPKTITLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDGLTVTVPSWRFDIEIEADLIEEVARIYGYD 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 481 HIPVTLPSGTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYMIEPNekaPVNLALPMSEERSQLRLSLV 560
Cdd:COG0072 472 NIPSTLPRAPLAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPEDADLFGLRRE---AVRLANPISEDLSVMRTSLL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 561 PQLLEAVSYNIARKNDSVALYEVGSIFLPtEAGELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGV 640
Cdd:COG0072 549 PGLLEAAAYNLNRGQKDVRLFEIGRVFLP-DEGEEPREPLHLAGVLTGNREPESWGGKARPVDFFDLKGDVEALLAALGV 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 641 SNqITYAPAKREGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSLVKIFGADAEETYYSAIPRFPSMTR 719
Cdd:COG0072 628 PK-LEFEAAEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPGpVYVFELDLDALLELARKVPKYKPISKFPAVRR 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 720 DMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKKSLAFSMTYFDAERTLTDEEVTEAHNRVLTTVEEK 799
Cdd:COG0072 707 DLALVVDEDVPAADVLDAIRKAAGKLLEDVRLFDVYEGKGVPEGKKSLAFSLTLQDPDRTLTDEEIDAAMDKIVAALEKK 786
|
....*..
gi 446420323 800 FGAELRK 806
Cdd:COG0072 787 FGAELRG 793
|
|
| pheT_bact |
TIGR00472 |
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of ... |
1-805 |
0e+00 |
|
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from Bacteria other than spirochetes, as well as a chloroplast-encoded form from Porphyra purpurea. The chloroplast-derived sequence is considerably shorter at the amino end. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273097 [Multi-domain] Cd Length: 797 Bit Score: 849.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 1 MFVSYRWLQEYVDIKDVTAQELADKITKSGIEVEGVEVLNKGVKGVVVGHVLECEKHPEADKLSKCLIDIGEEEPVQIIC 80
Cdd:TIGR00472 1 MKISLKWLREYVPLSEIDNEEIAEALTSIGLEVEAVIPFSKPLKGVVVGKVLEVEPHPNADKLKVCKVDIGEKEMLQIVC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 81 GAANIAKGLKVPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIDGKlvskeyADGIFIFPSDAEVGADALEILNL 160
Cdd:TIGR00472 81 GAPNVEAGKKVAVALPGAKLPNGLKIKKSKLRGVESEGMLCSESELGLDEK------SDGIIVLDEDAPLGTDIAEYLGL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 161 HDEVLELGLTPNRADCLNMLGVAYEVAAIYGREVKLPAIDLQETAEKTSDYISVSVEAKEENPLYIAKMVKNVKIGPSPM 240
Cdd:TIGR00472 155 DDDIIEVSITPNRGDCLSILGIARELAALFDLNLETPVPFEPETTETIDEGFKIEIEDPEVCPFYLGRVIKGVKVKPSPL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 241 WMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLgSKEIVVRLAKEGEKIETLDDQERTLQSHHLVITNGTKAL 320
Cdd:TIGR00472 235 WLKERLRRSGIRPINNIVDITNYVMLELGQPLHAFDADKI-EGNIVVRSAKEGESFTTLDGKERELKKGDLVIADDKKPL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 321 AVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEAIQHAAALMAKYAGGEALEG 400
Cdd:TIGR00472 314 AIAGVMGGKESGVTDTTTNIFLESAYFNPESIRKTARRLGISTDSSYRFERGVDPELTELALDRALNLILEIFGGEVISV 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 401 VVEADNLQIQERTVSVTAEKVNRVLGTNISASEMGTMFANLKFPFTEVEGTFHVNVPARRPDITISEDLVEEVGRLYGYD 480
Cdd:TIGR00472 394 VSDNYKEKAKEKKISLRIKKLNKILGIELSDEEVRDILKRLGFKVEKQKDGWEVTVPSYRHDIEIEEDLIEEIARIYGYD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 481 HIPVTLPSGTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYmIEPNEKAPVNLALPMSEERSQLRLSLV 560
Cdd:TIGR00472 474 NIPAEPLSVSSKLNKNNENYLLLRKLRTLLVGLGLNEVITYSFVDPEKAEKF-NFPKLENLVEIKNPLSNERSVLRTSLL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 561 PQLLEAVSYNIARKNDSVALYEVGSIFlpTEAGELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGV 640
Cdd:TIGR00472 553 PSLLEVLAYNQNRKNKDVKIFEIGKVF--AKDGEAVKEQLRLAILISGEKNPSSWNHKEEKVDFYDLKGDVESLLELLGL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 641 SNQITYAPAKR-EGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSLVKIFGADAEETYYSAIPRFPSMT 718
Cdd:TIGR00472 631 SDDVYFKNTAEnEELHPGQSATIYLKGKKIGFIGELHPEIAKKYDLKEpTFVFELDLDRLLESLKKVPKYRPISKFPAVT 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 719 RDMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKKSLAFSMTYFDAERTLTDEEVTEAHNRVLTTVEE 798
Cdd:TIGR00472 711 RDISFLVPKDVPANEIIKLIKKSGLELLEEVELFDVYQGKNIGEGKKSLALRLVLRDKERTLTDEEINKIVEKVLNALKE 790
|
....*..
gi 446420323 799 KFGAELR 805
Cdd:TIGR00472 791 KLGAELR 797
|
|
| EMAP |
COG0073 |
tRNA-binding EMAP/Myf domain [Translation, ribosomal structure and biogenesis]; |
1-785 |
5.82e-133 |
|
tRNA-binding EMAP/Myf domain [Translation, ribosomal structure and biogenesis];
Pssm-ID: 439843 [Multi-domain] Cd Length: 773 Bit Score: 413.87 E-value: 5.82e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 1 MFVSYRWLQEYVDIkDVTAQELADKITKSGIEVEGVEVLnKGVKGVVVGHVLECEKHPEADKLSKCLIDIGEEePVQIIC 80
Cdd:COG0073 1 MKVSLSWLKEYVDL-DLSPEELAEKLTMAGIEVEDFEKV-GGLDGLRVGKVLEAEPHPNADKLLVLQVDVGEE-TRQIVC 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 81 GAANIAKGLKVPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIDgklvskEYADGIFIFPSDAEVGADALEILNL 160
Cdd:COG0073 78 GAPNVYAGDKVPEALVGAQVPGVVNLKPRKIRGVESEGMLCSAEELGLG------EDHDGILELPEDAPPGDDAEYLLLL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 161 HDEVLELGLTPNRADCLNMLGVAYEVAAIYGREVKLPAIDLQETAEKTSDYISVSVEAKEENPLYIAKMVKNVKIGPSPM 240
Cdd:COG0073 152 DDVIIEILTTPNRDDLLSVGGAAREAAALGGLLLKPPAPPVVEGTDDAVLVVVVDDDACDRYYGRVVRGVVNVVVPPPPW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 241 WMQtRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLGSKEIVVRLAKEGEKIETLDDQERTLQSHHLVITNGTKAL 320
Cdd:COG0073 232 LRR-LLRRGGRRRIINVVDINNVVLLLLGQPHHAFDDDDLGGGIVVRRRRAEELLLLLLGDTTLLLDDLLLIDDDDDALA 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 321 AVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEAIQHAAALMAKYAGGEALEG 400
Cdd:COG0073 311 AAGGGGGGGGSSGSTTTTTLLLAAAAFFAAAGRRRRRRRLSSRSSRRRRREDDDDPRVAAAAAAAALLLIILGGGGGVAG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 401 VVEADNLQIQERTVSVTAEKVNRVLGTNISASEMGTMFANLKFPFTEVEGTFHVNVPARRPDITISEDLVEEVGRLYGYD 480
Cdd:COG0073 391 GVVDEGLPPPPPRIIRLRRRRRLLLLGIDIDEEELLLLLLLLGFEVEGEGESVVVPPPRRRDDVIEEDEEEEEARRYYYY 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 481 HIPVTLPSGTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSltSADKAKQYMIEPNEKAPVNLALPMSEERSQLRLSLV 560
Cdd:COG0073 471 DLPPPPPPAPPAVPEPPAARRRLRRRRRLLLLLGLEEAVTYS--SFSELLLALLLLFEAALLLLLPPSSLSSSLLLSLLL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 561 PQLLEAVSYNIARKNDSVALYEVGSIFLPTEAGELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGV 640
Cdd:COG0073 549 LLLLLVLLLLRRRNRNRRLFEGGEVFFGFEGGGLELLLAELEAGGALLLGGGGGAALGLAADDADDLAGVLLLLALLLGL 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 641 SNQITYAPAKREGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKNTFVFELSLVKIFGADAEETYYSAIPRFPSMTRD 720
Cdd:COG0073 629 LALLALAAAAPAAAAPGAGGAGGLLLGGGGGLGGLLPVLLKLLLLLLLALLFEVLLDELLLPAAVLLALPLVARPLLRAI 708
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446420323 721 MAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKKSLAFSMTYFDAERTLTDEEV 785
Cdd:COG0073 709 VVDVAAAVAAALAAVAAALALVVALLAVVLLVVVVDVGVGKVLKKLLLSLDLEVTLLDLEELELT 773
|
|
| syfB |
CHL00192 |
phenylalanyl-tRNA synthetase beta chain; Provisional |
155-806 |
2.76e-103 |
|
phenylalanyl-tRNA synthetase beta chain; Provisional
Pssm-ID: 214391 [Multi-domain] Cd Length: 704 Bit Score: 333.98 E-value: 2.76e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 155 LEILNLHDEVLELGLTPNRADCLNMLGVAYEVAAIYGREVK-----LPAIDLQETAEKtsdyISVSVEAKEENPLYIAKM 229
Cdd:CHL00192 39 VKIGGESDIILDISSTANRSDVLSIQGLSREISALFNSDPIklkyyNPSISWFDKLKN----LISNDSSKLNCSMFIAVI 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 230 VKNVKIGPSPMWMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLGSK------EIVVRLAKEGEKIETLDDQE 303
Cdd:CHL00192 115 IENIEIKDSPKWLQNRLSSSGFKSLNNLTDIQNYIMLETGQPIEIYDLDKIYSKnttsslALSSKFALQKSSFIASNSKN 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 304 RTLQSHHLVITNGTKALAVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEAIQ 383
Cdd:CHL00192 195 IELENNILVVQANNVIISIAGIISNEEIICDKNTKSILIEASIFDAAVIRKSSRKLGLRTDRSIRYEKSLKNDNLLEAYY 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 384 HAAALMAKYAGGEALEGVVEADNLQIQERTVSVTAEKVNRVLG-----TN---ISASEMGTMFANLKFPFT--EVEGTFH 453
Cdd:CHL00192 275 RLVSLLRILNPKLKCKFHFIYKKIKNSSRRIKLSYKKIKDILGpikinTNtryLSPKEITNALKRLNFKITydSLKLNWE 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 454 VNVPA-RRPDITISEDLVEEVGRLYGYDHIPVTLPSgTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTsadkaKQY 532
Cdd:CHL00192 355 VLIPSyRKDDIVREIDVIEEIARIYGFNNFLSKLPN-IKFIGRLDIDYNTRDKIRSYLRNLGLTELIHYSLV-----KQE 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 533 MIEPNEkapVNLALPMSEERSQLRLSLVPQLLEAVSYNIARKNDSVALYEVGSIFLPTEAGElpKEEQHLA-GVMTGLAL 611
Cdd:CHL00192 429 SFSKNE---IKLKNPLIKDYSTLRSSLLPGLIEAVQENLKQGNSTLEGFEIGHVFNLDSSSI--IEETELAgGIFGGIDI 503
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 612 HHAWQGEKKVVDFFVVKGVLEGLFDVLGVSNQITYAPAKREG--MHPGRTADIVL-DGEVIGFIGQLHPEAEKQLDV-KN 687
Cdd:CHL00192 504 RSSWSEKAQSLNWFEAKGIIENFFQKLNLPIYWKKYSDLDEKinFHPYCTSEIFLsNGQKIGIFGQLHPLLANKLNLnTE 583
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 688 TFVFELSLVKIFGADAEETY--YSAIPRFPSMTRDMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKK 765
Cdd:CHL00192 584 IYLFEINLDILQYSIQQNNLisYQPYSSYPKIIRDLSFIIKKSISISKIKELIYQNGDNLLESITLFDYYKGKSIPNGHT 663
|
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 446420323 766 SLAFSMTYFDAERTLTDEEVTEAHNRVLTTVEEKFGAELRK 806
Cdd:CHL00192 664 SLGLRLTFQSENKTLTNEEIDRIQQNLQKVLEKKLNAEIRE 704
|
|
| tRNA_synthFbeta |
pfam17759 |
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ... |
482-695 |
2.17e-93 |
|
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.
Pssm-ID: 465487 [Multi-domain] Cd Length: 214 Bit Score: 290.99 E-value: 2.17e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 482 IPVTLPSGTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYMIEPNEKAPVNLALPMSEERSQLRLSLVP 561
Cdd:pfam17759 1 IPSTLPKGPTTGGGLTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKDLDKLLEDDPRRKAVKLANPLSEELSVMRTSLLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 562 QLLEAVSYNIARKNDSVALYEVGSIFLPTEAGELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGVS 641
Cdd:pfam17759 81 GLLETLAYNLNRGNPDVRLFEIGRVFLPDELEELPREPRRLAGLLTGKRLPESWQGKARPVDFYDLKGIVEALLAALGID 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446420323 642 NqITYAPAKREGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSL 695
Cdd:pfam17759 161 D-YEFEAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPQpVYVFELDL 214
|
|
| B3_4 |
pfam03483 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
223-394 |
7.21e-88 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 427327 [Multi-domain] Cd Length: 174 Bit Score: 275.20 E-value: 7.21e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 223 PLYIAKMVKNVK-IGPSPMWMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLgSKEIVVRLAKEGEKIETLDD 301
Cdd:pfam03483 3 PRYFGRVIRGVKkNRPSPEWLQRRLRRAGIRPINNVVDITNYVMLELGQPLHAFDLDKI-AGDIVVRLAKGGEKFTTLDG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 302 QERTLQSHHLVITNGTKALAVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEA 381
Cdd:pfam03483 82 KERELDPGDLVIADDDGPVALAGIMGGEESEVTEDTTNIFLESAGFDPVAIRKTARRLGLRTDASYRFERGVDPELVEAA 161
|
170
....*....|...
gi 446420323 382 IQHAAALMAKYAG 394
Cdd:pfam03483 162 LDRATALLLELCG 174
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
223-394 |
3.45e-74 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 239.08 E-value: 3.45e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 223 PLYIAKMVKNVKIG-PSPMWMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLGSKEIVVRLAKEGEKIETLDD 301
Cdd:smart00873 2 PRYLGRVIRGVKNTrPSPEWLQERLHRAGIRPINNVVDITNYVSLETGQPLHAFDLDKIKGKDIPLRRAKEGEKFETLDG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 302 QERTLQSHHLVITNGTKALAVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEA 381
Cdd:smart00873 82 KEYELDEGDLVIADDEGPLALAGVMGGEESEVTENTTVIFLEPAIFSPRTIRITARTLNLFTDASGRFERGVDPELVELA 161
|
170
....*....|...
gi 446420323 382 IQHAAALMAKYAG 394
Cdd:smart00873 162 LDRAAALLLEICG 174
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
498-695 |
1.42e-69 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 227.53 E-value: 1.42e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 498 SAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYMIEPNEkaPVNLALPMSEERSQLRLSLVPQLLEAVSYNIARKNDS 577
Cdd:cd00769 1 PLQKLERKLRRLLAGLGFQEVITYSLTSPEEAELFDGGLDE--AVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKNKP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 578 VALYEVGSIFLPTEagELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGVSNQITYAPAKREGMHPG 657
Cdd:cd00769 79 LRLFEIGRVFLKDE--DGPEEEEHLAALLSGNREPESWQGKGRPVDFYDAKGILEALLRALGIIVEFELEELDADLFHPG 156
|
170 180 190
....*....|....*....|....*....|....*....
gi 446420323 658 RTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSL 695
Cdd:cd00769 157 RSAKIYVNGEVIGFIGELHPEVLKEFDLKEpVYAFELDL 195
|
|
| tRNA_bind_bactPheRS |
cd02796 |
tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. ... |
52-154 |
6.28e-43 |
|
tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate the 2'OH of the terminal ribose of tRNA they belong functionally to class 1 aaRSs. This domain has general tRNA binding properties and is believed to direct tRNAphe to the active site of the enzyme.
Pssm-ID: 239196 [Multi-domain] Cd Length: 103 Bit Score: 150.74 E-value: 6.28e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 52 LECEKHPEADKLSKCLIDIGEEEPVQIICGAANIAKGLKVPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIDgk 131
Cdd:cd02796 7 LEVEPHPNADKLNVCKVDIGENKPLQIVCGAPNVRAGDKVVVALPGAVLPGGLKIKKRKLRGVESEGMLCSAKELGLG-- 84
|
90 100
....*....|....*....|...
gi 446420323 132 lvskEYADGIFIFPSDAEVGADA 154
Cdd:cd02796 85 ----EDSDGIIELPEDAPVGTDI 103
|
|
| FDX-ACB |
smart00896 |
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some ... |
712-805 |
1.54e-38 |
|
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some phenylalanyl tRNA synthetases. The domain has a ferredoxin fold, consisting of an alpha+beta sandwich with anti-parallel beta-sheets (beta-alpha-beta x2).
Pssm-ID: 214893 [Multi-domain] Cd Length: 93 Bit Score: 137.94 E-value: 1.54e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 712 PRFPSMTRDMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGeKMEEGKKSLAFSMTYFDAERTLTDEEVTEAHNR 791
Cdd:smart00896 1 SKFPAVRRDLAFVVDEDVPAAELLDAIREAGGDLLEDVRLFDVYEG-GIPEGKKSLAYRLTYQSPDRTLTDEEVNAIHDK 79
|
90
....*....|....
gi 446420323 792 VLTTVEEKFGAELR 805
Cdd:smart00896 80 IVAALEKKFGAELR 93
|
|
| FDX-ACB |
pfam03147 |
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some ... |
712-805 |
9.49e-38 |
|
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some phenylalanyl tRNA synthetases. The domain has a ferredoxin fold.
Pssm-ID: 460826 [Multi-domain] Cd Length: 94 Bit Score: 135.69 E-value: 9.49e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 712 PRFPSMTRDMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKKSLAFSMTYFDAERTLTDEEVTEAHNR 791
Cdd:pfam03147 1 SKYPAVRRDLAFVVDEDVPAADILKAIREAGGELLESVELFDVYRGEKIPEGKKSLAFRLTFQSPERTLTDEEVNAIIEK 80
|
90
....*....|....
gi 446420323 792 VLTTVEEKFGAELR 805
Cdd:pfam03147 81 IVEALEKKFGAELR 94
|
|
| pheT_arch |
TIGR00471 |
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA ... |
151-699 |
1.48e-31 |
|
phenylalanyl-tRNA synthetase, beta subunit; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from eukaryotic cytosol, the Archaea, and spirochetes. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273096 [Multi-domain] Cd Length: 551 Bit Score: 130.26 E-value: 1.48e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 151 GADALEILNLHDEVlELGLTPNRADCLNMLGVAYEVAAIYGREVKLPAIDlqetAEKTSDYISVSVEAKEENPLYIAKMV 230
Cdd:TIGR00471 31 GDEIEGFDEESPEI-KVEFNPNRPDLLSVEGLARSLRGYLGIEKGLKSYD----SKKGDVKLTVDESVLQIRPFITGAVV 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 231 KNVKIG----PSPMWMQT----------RLMAAGIRPISNVVDITNYIlmeyGQPLHAFDYDKLGSKEivvrlakEGEKI 296
Cdd:TIGR00471 106 KGIILNdkvlESLIELQEklhwnigrnrRKVAIGIHDLDKVEFPFHYK----AVSPNGIKFVPLNSDQ-------EMTPD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 297 ETLDDQERTLQSHHL--------VITNGT-KALAVAGVMGGADSEVTNETVNVLIESAyfagqtvrrtskdlglrsessa 367
Cdd:TIGR00471 175 EILEEHPKGIRYAHIiedsdkfpLILDSKdDVLSMPPIINSELTKLTVNTRNLLIDVT---------------------- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 368 rfekGIDPTRTFEAIQHAAALMAKYAGG--EALEGVVEADNL---QIQERTVSVTAEKVNRVLGTNISASEMGTMFANLK 442
Cdd:TIGR00471 233 ----GTDKTAVEITLNIACTMFADRGDGriTVVEVERPDEHLgqpNLAPRFMEVSVEYINSLLGLNLSADEIAHSLKKMR 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 443 FPFTEVEGTFHVNVPARRPDITISEDLVEEVGRLYGYDHIPVTLPSgTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYS 522
Cdd:TIGR00471 309 LDAVQSDEKLKVVIPAYRVDILHEVDIIEDVAIGYGYNNFPPELPL-INTIGRLKPLNKVSDIIREIMVGLGFQEVIPLT 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 523 LTSADKAKQYM-IEPNEKAPVnlALPMSEERSQLRLSLVPQLLEAVSYNiarKNDSV--ALYEVGSI-FLPTEAGELPKE 598
Cdd:TIGR00471 388 LTSEEVNFKRMrIEDNNDVKV--ANPKTLEYTIVRTSLLPGLLETLSEN---KHHELpqKIFEIGDVvVKDDKSETRSRV 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 599 EQHLAGVMTGlalhhawqgekKVVDFFVVKGVLEGLFDVLGVSNQITyaPAKREGMHPGRTADIVLDGEVIGFIGQLHPE 678
Cdd:TIGR00471 463 VTKLAVGITH-----------SEANFNEIKSIVAALARELGIEYEIE--ESEHPSFIPGRGAKIVFEGKAIGHFGEIHPE 529
|
570 580
....*....|....*....|....
gi 446420323 679 AEKQLDVknTF---VFELSLVKIF 699
Cdd:TIGR00471 530 VLTNFEL--EFpvsAFEVNIEVFL 551
|
|
| tRNA_bindingDomain |
cd02153 |
The tRNA binding domain is also known as the Myf domain in literature. This domain is found in ... |
52-153 |
7.67e-27 |
|
The tRNA binding domain is also known as the Myf domain in literature. This domain is found in a diverse collection of tRNA binding proteins, including prokaryotic phenylalanyl tRNA synthetases (PheRS), methionyl-tRNA synthetases (MetRS), human tyrosyl-tRNA synthetase(hTyrRS), Saccharomyces cerevisiae Arc1p, Thermus thermophilus CsaA, Aquifex aeolicus Trbp111, human p43 and human EMAP-II. PheRS, MetRS and hTyrRS aminoacylate their cognate tRNAs. Arc1p is a transactivator of yeast methionyl-tRNA and glutamyl-tRNA synthetases. The molecular chaperones Trbp111 and CsaA also contain this domain. CsaA has export related activities; Trbp111 is structure-specific recognizing the L-shape of the tRNA fold. This domain has general tRNA binding properties. In a subset of this family this domain has the added capability of a cytokine. For example the p43 component of the Human aminoacyl-tRNA synthetase complex is cleaved to release EMAP-II cytokine. EMAP-II has multiple activities during apoptosis, angiogenesis and inflammation and participates in malignant transformation. An EMAP-II-like cytokine is released from hTyrRS upon cleavage. The active cytokine heptapeptide locates to this domain. For homodimeric members of this group which include CsaA, Trbp111 and Escherichia coli MetRS this domain acts as a dimerization domain.
Pssm-ID: 239066 [Multi-domain] Cd Length: 99 Bit Score: 104.91 E-value: 7.67e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 52 LECEKHPEADKLSKCLIDIGEEEPVQIICGAANIAK-----GLKVPVAKVgavlpgnfkIKKAKLRGEASHGMVCALQEL 126
Cdd:cd02153 7 VEAEPHPNADKLYVLKVDIGEEKPRQIVSGAANVYPpeelvGKKVVVAVN---------LKPKKLRGVESEGMLLSAEEL 77
|
90 100
....*....|....*....|....*..
gi 446420323 127 GIdgklvsKEYADGIFIFPSDAEVGAD 153
Cdd:cd02153 78 GL------EEGSVGILELPEDAPVGDR 98
|
|
| tRNA_bind |
pfam01588 |
Putative tRNA binding domain; This domain is found in prokaryotic methionyl-tRNA synthetases, ... |
52-153 |
7.62e-24 |
|
Putative tRNA binding domain; This domain is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1), human tyrosyl-tRNA synthetase, and endothelial-monocyte activating polypeptide II. G4p1 binds specifically to tRNA form a complex with methionyl-tRNA synthetases. In human tyrosyl-tRNA synthetase this domain may direct tRNA to the active site of the enzyme. This domain may perform a common function in tRNA aminoacylation.
Pssm-ID: 396251 [Multi-domain] Cd Length: 96 Bit Score: 96.16 E-value: 7.62e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 52 LECEKHPEADKLSKCLIDIGEEEPVQIICGAANIAKGLKvPVAKVGAVLPgnfKIKKAKLRGEASHGMVCALQELGIDGk 131
Cdd:pfam01588 7 VEAERHPNADKLLVCKVDVGEEEPRQIVSGAVNVYPPEE-LVGRLVVVVA---NLKPAKLRGVESEGMILSAEELDGGS- 81
|
90 100
....*....|....*....|..
gi 446420323 132 lvskeyaDGIFIFPSDAEVGAD 153
Cdd:pfam01588 82 -------VGLLEPPADVPPGTK 96
|
|
| B5 |
smart00874 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
412-479 |
6.64e-22 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 197942 [Multi-domain] Cd Length: 68 Bit Score: 89.86 E-value: 6.64e-22
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446420323 412 RTVSVTAEKVNRVLGTNISASEMGTMFANLKFPFTEVEGTFHVNVPARRPDITISEDLVEEVGRLYGY 479
Cdd:smart00874 1 RTITLRLERINRLLGLEILAEEIEEILKRLGFEVEVSGDTLEVTVPSYRFDILIEADLIEEVARIYGY 68
|
|
| PLN02265 |
PLN02265 |
probable phenylalanyl-tRNA synthetase beta chain |
412-695 |
1.13e-19 |
|
probable phenylalanyl-tRNA synthetase beta chain
Pssm-ID: 215149 [Multi-domain] Cd Length: 597 Bit Score: 93.59 E-value: 1.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 412 RTVSVTAEKVNRVLGTNISASEMGTMFANLKFP---FTEVEGTFHVNVPARRPDITISEDLVEEVGRLYGYDHIPVTLPS 488
Cdd:PLN02265 310 RTMEVDLSYINSSIGVSLDAEEVASLLNKMQLQaeqSSDDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPK 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 489 gTMTRGKLTSAQTKRRKVRRFLEGAGLYEAITYSLTS-ADKAKQYMIEPNEKAPVNLALPMSEERSQLRLSLVPQLLEAV 567
Cdd:PLN02265 390 -SMTVGKQQPLNQFSDLLRAEVAMAGFTEVLTWILCShKENFAMLNREDDGNSAVIIGNPRSADFEVVRTSLLPGLLKTL 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 568 SYNiarKNDS--VALYEVGSIFLPTEAGEL-PKEEQHLAGVMTGlalhhawqgekKVVDFFVVKGVLEGLFDVLGVS--- 641
Cdd:PLN02265 469 GHN---KDAPkpIKLFEVSDVVLLDESKDVgARNSRRLAALYCG-----------TTSGFEVIHGLVDRIMEVLGIPfve 534
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 446420323 642 ----NQITYAPAKREGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKN-TFVFELSL 695
Cdd:PLN02265 535 igdnNGYYVEPSNEPEYFPGRQASIIYKGKHVGTFGIVHPEVLNNFDIPDpCSFLELDL 593
|
|
| B5 |
pfam03484 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
414-479 |
1.33e-19 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 460942 [Multi-domain] Cd Length: 67 Bit Score: 83.21 E-value: 1.33e-19
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446420323 414 VSVTAEKVNRVLGTNISASEMGTMFANLKFPFTEV-EGTFHVNVPARRPDITISEDLVEEVGRLYGY 479
Cdd:pfam03484 1 ITLRLDRINRLLGIDLSAEEIVEILERLGFEVEEEdGDTLTVTVPSYRPDILHEADLIEEVARIYGY 67
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
52-133 |
3.65e-10 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 63.28 E-value: 3.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 52 LECEKHPEADKLSKCLIDIGEEEPVQIICGaanIAK--------GLKVpvakvgaVLPGNfkIKKAKLRGEASHGMVCAL 123
Cdd:PRK12267 559 LEAEKVEKSDKLLKLQVDLGEEEPRQIVSG---IAKfyppeelvGKKV-------VVVAN--LKPAKLMGEESQGMILAA 626
|
90
....*....|
gi 446420323 124 QElgiDGKLV 133
Cdd:PRK12267 627 ED---DGKLT 633
|
|
| tRNA_bind_EMAP-II_like |
cd02799 |
tRNA-binding-domain-containing EMAP2-like proteins. This family contains a diverse fraction of ... |
52-122 |
8.20e-10 |
|
tRNA-binding-domain-containing EMAP2-like proteins. This family contains a diverse fraction of tRNA binding proteins, including Caenorhabditis elegans methionyl-tRNA synthetase (CeMetRS), human tyrosyl- tRNA synthetase (hTyrRS), Saccharomyces cerevisiae Arc1p, human p43 and EMAP2. CeMetRS and hTyrRS aminoacylate their cognate tRNAs. Arc1p is a transactivator of yeast methionyl-tRNA and glutamyl-tRNA synthetases. This domain has general tRNA binding properties. In a subset of this family this domain has the added capability of a cytokine. For example the p43 component of the Human aminoacyl-tRNA synthetase complex is cleaved to release EMAP-II cytokine. EMAP-II has multiple activities during apoptosis, angiogenesis and inflammation and participates in malignant transformation. A EMAP-II-like cytokine also is released from hTyrRS upon cleavage. The active cytokine heptapeptide locates to this domain.
Pssm-ID: 239198 [Multi-domain] Cd Length: 105 Bit Score: 56.47 E-value: 8.20e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446420323 52 LECEKHPEADKLSKCLIDIGEEEPVQIICGAANIAKGLKVPVAKVgaVLPGNfkIKKAKLRGEASHGMV-CA 122
Cdd:cd02799 14 LKVRKHPDADSLYVEEIDLGEEEPRTIVSGLVKFVPLEQMQNRLV--VVLCN--LKPRKMRGVKSQGMVlCA 81
|
|
| PLN02788 |
PLN02788 |
phenylalanine-tRNA synthetase |
708-805 |
1.41e-08 |
|
phenylalanine-tRNA synthetase
Pssm-ID: 215422 [Multi-domain] Cd Length: 402 Bit Score: 57.85 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 708 YSaipRFPSMTRDMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKmeEGKKSLAFSMTYFDAERTLTDEEVTE 787
Cdd:PLN02788 310 YS---KYPPCYKDISFWISDEFTENNLCEVVRGIAGDLVEEVKLIDNFTNPK--KGKTSHCYRIVYRSMERSLTDEEINA 384
|
90
....*....|....*...
gi 446420323 788 AHNRVLTTVEEKFGAELR 805
Cdd:PLN02788 385 LQDKVREEVQKKLGVELR 402
|
|
| B3/B4 |
COG3382 |
B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase) [General function prediction only] ... |
250-406 |
3.19e-07 |
|
B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase) [General function prediction only];
Pssm-ID: 442609 [Multi-domain] Cd Length: 233 Bit Score: 52.16 E-value: 3.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 250 GIRPISNVVDITNYILMEYGQPLHAFDYDKLGSkEIVVRLAKEGEKIETLDDQER-TLQSHHLVITNGtkalavAGVMG- 327
Cdd:COG3382 94 GLPRINPLVDLYNAVSLRYLLPIGGYDLDKIEG-DLRLRLARGGESFLPIGGDEEePPEPGEVVYADD------EGVFCr 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 328 ------GADSEVTNETVNVLIESAYFAgqtvrrtskdlglrsessarfekGIDPTRTFEAIQHAAALMAKYAGGEALE-G 400
Cdd:COG3382 167 rwpwrdSERTKVTEETKNALFIIEGLP-----------------------GVSAEDLEAALDELAELLERYLGGEVVKtR 223
|
....*.
gi 446420323 401 VVEADN 406
Cdd:COG3382 224 ILDADN 229
|
|
| pheS_mito |
TIGR00469 |
phenylalanyl-tRNA synthetase, mitochondrial; Unlike all other known phenylalanyl-tRNA ... |
706-804 |
5.59e-06 |
|
phenylalanyl-tRNA synthetase, mitochondrial; Unlike all other known phenylalanyl-tRNA synthetases, the mitochondrial form demonstrated from yeast is monomeric. It is similar to but longer than the alpha subunit (PheS) of the alpha 2 beta 2 form found in Bacteria, Archaea, and eukaryotes, and shares the characteristic motifs of class II aminoacyl-tRNA ligases. This model models the experimental example from Saccharomyces cerevisiae (designated MSF1) and its orthologs from other eukaryotic species. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 129561 [Multi-domain] Cd Length: 460 Bit Score: 49.69 E-value: 5.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 706 TYYSAIPRFPSMTRDMAVVV--TKETKAG----EMKQVIAEAGGELLKDVTLFDLYEGEKMeeGKKSLAFSMTYFDAERT 779
Cdd:TIGR00469 358 PKFKPISHHPGCFNDLAFWLpeDIEDDAGfhenDFMDIIRNIAGDLVEQIKLVDKFKHPKT--GKKSMCFRINYQHMDRN 435
|
90 100
....*....|....*....|....*
gi 446420323 780 LTDEEVTEAHNRVLTTVEEKFGAEL 804
Cdd:TIGR00469 436 LTNAEVNEIHDMIASALVDEFNVEI 460
|
|
| tRNA_bind_EcMetRS_like |
cd02800 |
tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like ... |
52-122 |
1.09e-05 |
|
tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins. This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties. MetRS aminoacylates methionine transfer RNAs (tRNAmet). AaTrbp111 is structure-specific molecular chaperone recognizing the L-shape of the tRNA fold. AaTrbp111 plays a role in nuclear trafficking of tRNAs. The functional unit of EcMetRs and AaTrbp111 is a homodimer, this domain acts as the dimerization domain.
Pssm-ID: 239199 [Multi-domain] Cd Length: 105 Bit Score: 44.80 E-value: 1.09e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446420323 52 LECEKHPEADKLSKCLIDIGeEEPVQIICGaanIAK--------GLKVpvakvgaVLPGNFkiKKAKLRGEASHGMVCA 122
Cdd:cd02800 17 LEAERVEGSDKLLKLTVDLG-EEERQIVSG---IAKfyppeelvGKKV-------VVVANL--KPRKLRGVESQGMILA 82
|
|
| metG_C_term |
TIGR00399 |
methionyl-tRNA synthetase C-terminal region/beta chain; The methionyl-tRNA synthetase (metG) ... |
52-134 |
5.50e-05 |
|
methionyl-tRNA synthetase C-terminal region/beta chain; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ligase. This model describes a region of the methionyl-tRNA synthetase that is present at the C-terminus of MetG in some species (E. coli, B. subtilis, Thermotoga maritima, Methanobacterium thermoautotrophicum), and as a separate beta chain in Aquifex aeolicus. It is absent in a number of other species (e.g. Mycoplasma genitalium, Mycobacterium tuberculosis), while Pyrococcus horikoshii has both a full length MetG and a second protein homologous to the beta chain only. Proteins hit by this model should be called methionyl-tRNA synthetase beta chain if and only if the model metG hits a separate protein not also hit by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273059 [Multi-domain] Cd Length: 137 Bit Score: 43.57 E-value: 5.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 52 LECEKHPEADKLSKCLIDIGEEEpVQIICGaanIAKGLKvPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIDGK 131
Cdd:TIGR00399 48 LKAERVEKSDKLLKLKLDLGDEK-RQIVSG---IAGYYT-PEELVGKKVIVVANLKPAKLFGVKSEGMILAAEDDGKVLF 122
|
...
gi 446420323 132 LVS 134
Cdd:TIGR00399 123 LLS 125
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
52-164 |
3.92e-04 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 43.99 E-value: 3.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446420323 52 LECEKHPEADKLSKCLIDIGeEEPVQIICGaanIAKGLKvPVAKVGA--VLPGNFkiKKAKLRGEASHGMVCAlqelgid 129
Cdd:PRK00133 584 VEAEKVEGADKLLKLTLDLG-EETRQVFSG---IKSAYD-PEELVGKlvVMVANL--APRKMKFGVSEGMVLA------- 649
|
90 100 110
....*....|....*....|....*....|....*
gi 446420323 130 gklvskeyadgififpsdAEVGADALEILNLHDEV 164
Cdd:PRK00133 650 ------------------AGPGGGDLFLLEPDEGA 666
|
|
| PLN02610 |
PLN02610 |
probable methionyl-tRNA synthetase |
55-122 |
8.18e-03 |
|
probable methionyl-tRNA synthetase
Pssm-ID: 215329 [Multi-domain] Cd Length: 801 Bit Score: 39.76 E-value: 8.18e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446420323 55 EKHPEADKLSKCLIDIGEEEPVQIICGAANIAKGLKVPVAKVgAVLpgnFKIKKAKLRGEASHGMVCA 122
Cdd:PLN02610 654 EKHPDADSLYVEEIDVGEGAPRTVVSGLVKYIPLEEMQNRKV-CVL---CNLKPAAMRGIKSQAMVLA 717
|
|
| |
