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Conserved domains on  [gi|446423698|ref|WP_000501553|]
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MULTISPECIES: ABC transporter permease [Bacillus]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 29-308 1.17e-107

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 315.13  E-value: 1.17e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  29 SRKKEVFRKFVSNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSEHWFGTDDLGRDIWARTWAGGKISL 108
Cdd:COG1173    3 SRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 109 TVGLVAAALDIGLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGM 188
Cdd:COG1173   83 LVGLLAVLIALVIGVLLGLLAGYFGGW------VDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGY 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 189 ARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTN 268
Cdd:COG1173  157 ARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLS 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 446423698 269 DALGTLLSGeWWQLFFPAIMIALIMFAFNAIGDGLQDAID 308
Cdd:COG1173  237 EGRNYLLTA-PWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 29-308 1.17e-107

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 315.13  E-value: 1.17e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  29 SRKKEVFRKFVSNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSEHWFGTDDLGRDIWARTWAGGKISL 108
Cdd:COG1173    3 SRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 109 TVGLVAAALDIGLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGM 188
Cdd:COG1173   83 LVGLLAVLIALVIGVLLGLLAGYFGGW------VDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGY 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 189 ARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTN 268
Cdd:COG1173  157 ARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLS 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 446423698 269 DALGTLLSGeWWQLFFPAIMIALIMFAFNAIGDGLQDAID 308
Cdd:COG1173  237 EGRNYLLTA-PWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 36-310 6.33e-61

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 196.98  E-value: 6.33e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  36 RKFVSNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSE--HWFGTDDLGRDIWARTWAGGKISLTVGLV 113
Cdd:PRK15406  31 RRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWGMMSSAPDMEsgHYFGTDSSGRDLLVRVAIGGRISLMVGVA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 114 AAALDIGLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGMARLIR 193
Cdd:PRK15406 111 AALVAVVVGTLYGSLSGYLGGK------VDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVR 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 194 AQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTNDALGT 273
Cdd:PRK15406 185 GQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANS 264

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 446423698 274 LLSGEWWqLFFPAIMIALIMFAFNAIGDGLQDAIDPK 310
Cdd:PRK15406 265 MEVSPWL-LLFPAGFLVVTLFCFNFIGDGLRDALDPK 300
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 44-308 6.54e-61

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 195.30  E-value: 6.54e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698   44 AVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSEHWFGTDDLGRDIWARTWAGGKISLTVGLVAAALDIGLGV 123
Cdd:TIGR02790   1 VVSALLIIAVLFLLAIFAPWIAPHDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  124 LIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGMARLIRAQVLSLKQRE 203
Cdd:TIGR02790  81 LIGGLAGYIGGR------VDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQRE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  204 FVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTNDALGTLLSGEwWQLF 283
Cdd:TIGR02790 155 FVLAARTSGASHWQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQP-LLMI 233

                         250       260
                  ....*....|....*....|....*
gi 446423698  284 FPAIMIALIMFAFNAIGDGLQDAID 308
Cdd:TIGR02790 234 YPGLAILISVMAFNLLGDALRDHLG 258
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 122-313 3.14e-16

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 75.41  E-value: 3.14e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  122 GVLIGGFSGYVRGRnrlgtLIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLF----TIIIALALTGWIGMARLIRAQVL 197
Cdd:pfam00528   1 GIPLGIIAALRRGR-----RLDRLLRPLIDLLQALPSFVLAILLVVIAILSILghgiLPAIILALLGWAGYARLIRRAAL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  198 SLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFI----GLGVQSPAASWGTMTNDALGt 273
Cdd:pfam00528  76 RSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYPEIQG- 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 446423698  274 llsgewwqlffPAIMIALIMFAFNAIGDGLQDAIDPKIIK 313
Cdd:pfam00528 155 -----------PVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 106-303 3.17e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.00  E-value: 3.17e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 106 ISLTVGLVAAALDIGLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIP--------YLLIVILLLIVMKPGLFTII 177
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGK------LDRLLRRIIDLLLSLPslvlglllVLLFGVLLGWGILPGLGLPA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 178 IALALTGWIGMARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVq 257
Cdd:cd06261   77 LILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE- 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446423698 258 SPAASWGTMTNdalgtllsgewWQLFFPAIMIALIMFAFNAIGDGL 303
Cdd:cd06261  156 APGPGTGLLLI-----------FAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 29-308 1.17e-107

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 315.13  E-value: 1.17e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  29 SRKKEVFRKFVSNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSEHWFGTDDLGRDIWARTWAGGKISL 108
Cdd:COG1173    3 SRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 109 TVGLVAAALDIGLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGM 188
Cdd:COG1173   83 LVGLLAVLIALVIGVLLGLLAGYFGGW------VDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGY 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 189 ARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTN 268
Cdd:COG1173  157 ARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLS 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 446423698 269 DALGTLLSGeWWQLFFPAIMIALIMFAFNAIGDGLQDAID 308
Cdd:COG1173  237 EGRNYLLTA-PWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 36-310 6.33e-61

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 196.98  E-value: 6.33e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  36 RKFVSNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSE--HWFGTDDLGRDIWARTWAGGKISLTVGLV 113
Cdd:PRK15406  31 RRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWGMMSSAPDMEsgHYFGTDSSGRDLLVRVAIGGRISLMVGVA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 114 AAALDIGLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGMARLIR 193
Cdd:PRK15406 111 AALVAVVVGTLYGSLSGYLGGK------VDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVR 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 194 AQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTNDALGT 273
Cdd:PRK15406 185 GQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANS 264

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 446423698 274 LLSGEWWqLFFPAIMIALIMFAFNAIGDGLQDAIDPK 310
Cdd:PRK15406 265 MEVSPWL-LLFPAGFLVVTLFCFNFIGDGLRDALDPK 300
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 44-308 6.54e-61

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 195.30  E-value: 6.54e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698   44 AVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSEHWFGTDDLGRDIWARTWAGGKISLTVGLVAAALDIGLGV 123
Cdd:TIGR02790   1 VVSALLIIAVLFLLAIFAPWIAPHDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  124 LIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGMARLIRAQVLSLKQRE 203
Cdd:TIGR02790  81 LIGGLAGYIGGR------VDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQRE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  204 FVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTNDALGTLLSGEwWQLF 283
Cdd:TIGR02790 155 FVLAARTSGASHWQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQP-LLMI 233

                         250       260
                  ....*....|....*....|....*
gi 446423698  284 FPAIMIALIMFAFNAIGDGLQDAID 308
Cdd:TIGR02790 234 YPGLAILISVMAFNLLGDALRDHLG 258
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
40-310 1.90e-53

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 177.32  E-value: 1.90e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  40 SNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSEHWFGTDDLGRDIWARTWAGGKISLTVGLVAAALDI 119
Cdd:PRK09881  29 GSPLTVTGAVIIVLMLLMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAG 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 120 GLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGMARLIRAQVLSL 199
Cdd:PRK09881 109 MIGSLLGCLSGVLGGR------ADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAMLAIAIVRIPFYVRLARGQALVV 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 200 KQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTNDALGTLLSgEW 279
Cdd:PRK09881 183 RQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLD-QW 261

                        250       260       270
                 ....*....|....*....|....*....|.
gi 446423698 280 WQLFFPAIMIALIMFAFNAIGDGLQDAIDPK 310
Cdd:PRK09881 262 WYCAFPGAAILLTAVGFNLFGDGIRDLLDPK 292
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 33-311 3.32e-52

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 174.15  E-value: 3.32e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  33 EVFRKFVSNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVK-EATNLPPSSEHWFGTDDLGRDIWARTWAGGKISLTVG 111
Cdd:PRK15082  27 EFWRRFRRQHVALVAGLFVLLLIVVAIFAPWIAPYDAENYFDyDALNAGPSLQHWFGVDSLGRDIFSRILVGARISLAAG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 112 LVAAALDIGLGVLIGGFSGYVRGrnrlgtLIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGMARL 191
Cdd:PRK15082 107 FFSVAIGAAIGTVLGLLAGYYEG------WWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAFARL 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 192 IRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTNDAL 271
Cdd:PRK15082 181 VRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAMLNEAR 260

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 446423698 272 GTLLSGEWWQLfFPAIMIALIMFAFNAIGDGLQDAIDPKI 311
Cdd:PRK15082 261 ADMVIAPHVAL-FPSLAIFLTVLAFNLLGDGLRDALDPKI 299
nikC PRK10417
nickel transporter permease NikC; Provisional
 46-312 3.58e-51

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 170.62  E-value: 3.58e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  46 LGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSEHWFGTDDLGRDIWARTWAGGKISLTVGLVAAALDIGLGVLI 125
Cdd:PRK10417   8 LALIIIALLALIALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 126 GGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGWIGMARLIRAQVLSLKQREFV 205
Cdd:PRK10417  88 GGSAGLLGGR------VDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 206 IAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGTMTNDAlGTLLSGEWWQLFFP 285
Cdd:PRK10417 162 LAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDA-RQYIWTQPLLMFWP 240

                        250       260
                 ....*....|....*....|....*..
gi 446423698 286 AIMIALIMFAFNAIGDGLQDAIDPKII 312
Cdd:PRK10417 241 GLALFISVMAFNLLGDALRDHLDPHLV 267
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
32-311 8.33e-47

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 160.33  E-value: 8.33e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  32 KEVFRKFVSNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPP------SSEHWFGTDDLGRDIWARTWAGGK 105
Cdd:PRK10913  20 QEFWHYFKRNKGAVVGLVYVVIMLFIAIFANWIAPHNPAEQFRDALLAPPvwqeggSWAHILGTDDVGRDVLSRLMYGAR 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 106 ISLTVGLVAAALDIGLGVLIGGFSGYVRGrnrlgtLIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLFTIIIALALTGW 185
Cdd:PRK10913 100 LSLLVGCLVVVLSLVMGVILGLIAGYFGG------LVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIVNAALALTFVAL 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 186 IGMARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAASWGT 265
Cdd:PRK10913 174 PHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGT 253

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 446423698 266 MTNDALGTLLSGeWWQLFFPAIMIALIMFAFNAIGDGLQDAIDPKI 311
Cdd:PRK10913 254 MLSDVLQFAQSA-WWVVTFPGLAILLTVLAFNLMGDGLRDALDPKL 298
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 80-310 1.55e-39

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 142.21  E-value: 1.55e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  80 PPSSEHWFGTDDLGRDIWARTWAGGKISLTVGLVAAALDIGLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYL 159
Cdd:COG4239  116 PPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGR------VDLLFQRFIEIWSSMPEL 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 160 LIVILLLIVMKPGLFTIIIALALTGWIGMARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTI 239
Cdd:COG4239  190 YLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAMVATLTFLPFIL 269

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446423698 240 PAAIFSESFLSFIGLGVQSPAASWGTMTNDALGTLLSgeWWQLF--FPAIMIALIMFAFnaIGDGLQDAIDPK 310
Cdd:COG4239  270 SGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQA--PWLGLsaFVVLALMLSLLVF--IGEAVRDAFDPR 338
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
29-311 4.42e-33

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 124.16  E-value: 4.42e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  29 SRKKEVFRKFVSNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSE------HWFGTDDLGRDIWARTWA 102
Cdd:COG4171   14 SPLKQIWQSFRKNPLAMIGLYGFLFLILLALFGPLLAPYSPDQQFIGALLLPPSWDdngdvsFFLGTDDLGRDILSRLLY 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 103 GGKISLTVGLVAAALDIGLGVLIGGFSGYVRG-RNR-LGTLIDewiirgieVLYGIPYLLIVILLLIVMKPGLFTIIIAL 180
Cdd:COG4171   94 GARYTFGSALLVVLAAAIIGGIIGILAGMSRGlKSSiLNHLLD--------TLLSIPSLLLAIIIVALLGPGLENAMLAI 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 181 ALTGWIGMARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPA 260
Cdd:COG4171  166 TLALLPQFIHAIYQAVHQELKKEYVLAARLDGASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQLPS 245

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446423698 261 ASWGTMTNDALgTLLSGEWWQLFFPAIMIALIMFAFNAIGDGLQDAIDPKI 311
Cdd:COG4171  246 PEWGAMLGDSL-ELIYLAPWTVILPGLAIMFSVLIVNLVGDGLRRALNKGV 295
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 80-309 2.65e-28

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 112.38  E-value: 2.65e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  80 PPSSEHWFGTDDLGRDIWARTWAGGKISLTVGLVAAALDIGLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIPYL 159
Cdd:PRK15021 116 PPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGK------VDLWGQRFIEVWSGMPTL 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 160 LIVILLLIVMKPGLFTIIIALALTGWIGMARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTI 239
Cdd:PRK15021 190 FLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFIL 269

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446423698 240 PAAIFSESFLSFIGLGVQSPAASWGTMTNDALGTlLSGEWWQL--FFP-AIMIALIMFafnaIGDGLQDAIDP 309
Cdd:PRK15021 270 CSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNN-LQAPWLGItaFLSvAILLSLLIF----IGEAVRDAFDP 337
PRK15111 PRK15111
peptide ABC transporter permease SapC;
29-308 1.10e-25

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 104.01  E-value: 1.10e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  29 SRKKEVFRKFVSNPIAVLGSVTLLLIIVFSLIGESLTPFTASEQVKEATNLPPSSEHW------FGTDDLGRDIWARTWA 102
Cdd:PRK15111  14 GTLRTAWRKFYSDALAMVGLYGCAGLALLCLFGGWLAPYGIDQQFLGYQLLPPSWSRYgevsffLGTDDLGRDVLSRLLS 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 103 GGKISLTVGLVAAALDIGLGVLIGGFSGYVRGrnrLGTLIDEWIIrgiEVLYGIPYLLIVILLLIVMKPGLFTIIIALAL 182
Cdd:PRK15111  94 GAAPTVGGAFVVTLAATLCGLVLGVFAGATHG---LRSAVLNHIL---DTLLSIPSLLLAIIVVAFAGPSLSHAMFAVWL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 183 TGWIGMARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVQSPAAS 262
Cdd:PRK15111 168 ALLPRMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQLPSPE 247

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 446423698 263 WGTMTNDALgTLLSGEWWQLFFPAIMIALIMFAFNAIGDGLQDAID 308
Cdd:PRK15111 248 WGAMLGDSL-ELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAII 292
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 122-313 3.14e-16

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 75.41  E-value: 3.14e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  122 GVLIGGFSGYVRGRnrlgtLIDEWIIRGIEVLYGIPYLLIVILLLIVMKPGLF----TIIIALALTGWIGMARLIRAQVL 197
Cdd:pfam00528   1 GIPLGIIAALRRGR-----RLDRLLRPLIDLLQALPSFVLAILLVVIAILSILghgiLPAIILALLGWAGYARLIRRAAL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  198 SLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFI----GLGVQSPAASWGTMTNDALGt 273
Cdd:pfam00528  76 RSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYPEIQG- 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 446423698  274 llsgewwqlffPAIMIALIMFAFNAIGDGLQDAIDPKIIK 313
Cdd:pfam00528 155 -----------PVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 106-303 3.17e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.00  E-value: 3.17e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 106 ISLTVGLVAAALDIGLGVLIGGFSGYVRGRnrlgtlIDEWIIRGIEVLYGIP--------YLLIVILLLIVMKPGLFTII 177
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGK------LDRLLRRIIDLLLSLPslvlglllVLLFGVLLGWGILPGLGLPA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 178 IALALTGWIGMARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGHLIPNLTGIIIVNLSFTIPAAIFSESFLSFIGLGVq 257
Cdd:cd06261   77 LILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE- 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446423698 258 SPAASWGTMTNdalgtllsgewWQLFFPAIMIALIMFAFNAIGDGL 303
Cdd:cd06261  156 APGPGTGLLLI-----------FAILFPGDLGVAAAVALILLLLSL 190
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 95-311 5.35e-06

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 47.37  E-value: 5.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698  95 DIWARTWAggkiSLTVGLVAAALDIGLGVLIGGFSGYvrgrnRLGTLIDEWIIRGIEVLYGIPY---------------- 158
Cdd:COG0601   90 LIAERLPV----TLELALLALLLALLIGIPLGILAAL-----RRGSWLDRLITVLALLGISIPSfwlglllillfavklg 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 159 ---LLIVILLLIVMKPGLFTII---IALALTGWIGMARLIRAQVLSLKQREFVIAAERLGTSHMKIIYGH-----LIPNL 227
Cdd:COG0601  161 wlpVSGRVSPWEDFLDALRHLIlpaLTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHalrnaLIPVV 240

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446423698 228 TgIIIVNLSFTIPAAIFSESFLSFIGLgvqspaaswGTMTNDALGtllsgewwQLFFPAIM-----IALIMFAFNAIGDG 302
Cdd:COG0601  241 T-VLGLQLGGLLGGAVVVETVFSWPGL---------GRLLVDAIL--------NRDYPVVQgivllIAVLVVLVNLLVDL 302


                 ....*....
gi 446423698 303 LQDAIDPKI 311
Cdd:COG0601  303 LYALLDPRI 311
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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