|
Name |
Accession |
Description |
Interval |
E-value |
| PTS-IIBC-Tre |
TIGR01992 |
PTS system, trehalose-specific IIBC component; This model represents the fused enzyme II B and ... |
6-470 |
0e+00 |
|
PTS system, trehalose-specific IIBC component; This model represents the fused enzyme II B and C components of the trehalose-specific PTS sugar transporter system. Trehalose is converted to trehalose-6-phosphate in the process of translocation into the cell. These transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci and Streptococci which contain their own A domain as a C-terminal fusion. This family is closely related to the sucrose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively). In E. coli, B. subtilis and P. fluorescens the presence of this gene is associated with the presence of trehalase which degrades T6P to glucose and glucose-6-P. Trehalose may also be transported (in Salmonella) via the mannose PTS or galactose permease systems, or (in Sinorhizobium, Thermococcus and Sulfolobus, for instance) by ABC transporters.
Pssm-ID: 273916 Cd Length: 462 Bit Score: 622.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 6 RKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPGDVDRVYAELITLAGM 85
Cdd:TIGR01992 1 RKDAKAILEAIGGKENIEAATHCVTRLRFVLKDPSKVDVKALEQIDLVKGSFTNAGQFQVVIGPGTVDKVYAALIAETGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 86 EESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDGKNLLDVYPNLGGLWDLINMMA 165
Cdd:TIGR01992 81 AEVSKEEVKKAAAKNMNPLQRLIKLLADIFIPILPAIITAGLLMGINNLLGAKGMSFGGQTLVEVYPQWAGIYNFINLIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 166 NTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGLEgqkIEYFNILGLFQIEKVGYQGQILPVL 245
Cdd:TIGR01992 161 ETAFHFLPALIGWSAVKKFGGSPILGIVLGLMLVHPQLLNAYLYGQALAEGN---IPVWDLFGFFEIQKVGYQGQVLPAL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 246 VAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLFGALYAPLV 325
Cdd:TIGR01992 238 LAGYVLAVIEKWLRKRVPDAIQLLVVPPVSLLVTGFLAHAIIGPIGRLIGNGITSGVTALFTSAAWLGGAIFGLLYAPLV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 326 ITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNLRNKF 405
Cdd:TIGR01992 318 ITGLHHMFLAVDLQLIGSLGGTFLWPMIALSNIAQGSAALGIIFMSRNEKEKGLSLTSAISAYLGVTEPAMFGVNLKYKF 397
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446436084 406 PFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMIIAVVIPFTLTWLFAK 470
Cdd:TIGR01992 398 PFIAAMIGSGLAGLLSGLNGVLANSIGVGGLPGFISIQPQYWPVFAIGMAIAIVVPFVLTIFFSK 462
|
|
| PRK11007 |
PRK11007 |
PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional |
1-471 |
7.87e-151 |
|
PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional
Pssm-ID: 182896 Cd Length: 473 Bit Score: 437.97 E-value: 7.87e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 1 MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPgDVDRVYAELI 80
Cdd:PRK11007 2 MSKINQQDIDRLIELVGGRENIATVSHCITRLRFVLNDPANADPKEIEQLPMVKGCFTNAGQFQVVIGT-EVGDYYKALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 81 TLAGMEESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGakDL-FFDGKNLLDVYPNLGGLWD 159
Cdd:PRK11007 81 ATTGQAEVDKEQAKKAARQNMKWHERLISHFAEIFFPLLPALISGGLILGFRNVIG--DIpMSDGQTLAQMYPFWQTIYD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 160 LINMMANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKaatglegQKIEYFNiLGLFQIEKVGYQG 239
Cdd:PRK11007 159 FLWLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQ-------QLPEVWD-FGLFSIEKVGYQA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 240 QILPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDlltvglvGVYETV--------PV 311
Cdd:PRK11007 231 QVIPALLAGLALGFIETRLKRIVPDYLYLVVVPVCSLILAVFLAHALIGPFGRMIGD-------GVAFAVkalmtgsfAP 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 312 VGAVLFGALYAPLVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGI 391
Cdd:PRK11007 304 IGAALFGFLYAPLVITGVHQTTLAIDLQMIQSMGGTPVWPLIALSNIAQASAVVGIIIISRKHNEREISVPAAISAYLGV 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 392 TEPAMFGVNLRNKFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMIIAVVIPFTLTWLFAKR 471
Cdd:PRK11007 384 TEPAMYGINLKYRFPMLCAMIGSALAGLICGLNGVMANGIGVGGLPGILSIQPQYWQVYALAMLVAIVVPIVLTSFIYKR 463
|
|
| PtsG1 |
COG1263 |
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific ... |
98-475 |
1.84e-107 |
|
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism];
Pssm-ID: 440875 [Multi-domain] Cd Length: 463 Bit Score: 326.90 E-value: 1.84e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 98 NQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDGknlldvyPNLGGLWDLINMMANTAFVFLPALVG 177
Cdd:COG1263 2 KKKKNPLFRFLQKIGGIFMPPIPVLPAAGLLLGLGALLTNPGLLGEG-------SFLSGTYQILNAAGDAVFYFLPLLFA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 178 WSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKaatglegqkiEYFNILGLFQieKVGYQGQILPVLVAAFVLSKVEIF 257
Cdd:COG1263 75 IGAAKGFGGNPALAAVIGYLLVHPTLLNAYAVAG----------GYISFLGIPT--LIGYQGGVFPGILAGWLAAYLEKF 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 258 LKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLFGALYAPLVITGMHHMFIAID 337
Cdd:COG1263 143 LKKKLPDALGFFFVPILTLLIMVPLALLVIGPIWPPIGNGIAAGLGWIYGLAGAIGGFIYGFLYRLLVPTGLHHGLNPIF 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 338 LQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISK-NQNDKSMASTSAISAYF-GITEPAMFGVNLRNKFPFYAAIIGSA 415
Cdd:COG1263 223 WFLLGGTGDDGLFPILAAAMFGQPGAALAVYLKAKpNKKVKGLAISAALTAFLtGITEPAEFGFNLVAPKLFIAHAIGGG 302
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446436084 416 VAAIFITLNGVLAPAIGIGGLPAFISIIP---KSIPMFIVGMIIAVVIPFTLTWLFAKRVKQK 475
Cdd:COG1263 303 LGGAIAGLLGVKAFSFGVGGLIDFPSILNpgaTNLLLYLIGLVIAFVYYFVFTFLIGREDEEE 365
|
|
| PTS_EIIC |
pfam02378 |
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ... |
112-407 |
2.41e-32 |
|
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.
Pssm-ID: 367061 Cd Length: 315 Bit Score: 125.54 E-value: 2.41e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 112 SDVFMPILPAIVTAGLLMGINNLLGAKDLFFdgknlLDVYPNLGGLWDLINMMANTAFVFLPALVGWSATKRF-GGSPIL 190
Cdd:pfam02378 1 GDGFMPPIPLLIAGGILLGLGNLPNDTTGLP-----AGGFTGDSPLAEILKQAGSAAFGILPILFAIGIAYGLaGGDGVA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 191 GIVMGLMLVHPALLNAWDYGKAATGLEGQKieyfNILGLFQIEKvGYQGQILPVLVAAFVLSKVEIFLKKHVPNAIQLLV 270
Cdd:pfam02378 76 GAAGLIGLLSFNLAAAISVALTAAGLSGGG----NILGIGLGAT-GVFGAIIPGLLAAYLYNRFEKNITIKLPDSLPFFV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 271 VPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVG----VYETVPVVGAVLFGALYAPLVITGMHHMFIAIDLQLIA---- 342
Cdd:pfam02378 151 GKRFVPIITGFVTLLVIGPVLGLIWPAIQGGLNAlgllLIIAGGILGGLIFGFLERLLWPFGLHGAFIAIFWFLPIggsn 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446436084 343 --------QHGGTFIWP---MIALSNIAQGSAAL-AMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNLRNKFPF 407
Cdd:pfam02378 231 pianqqayGAGAAHILTggfDVMFGGPGATLALYaAAFLFKKSKVKKLLGSAALTPFLFGITEPLEFGFPFVLNPPF 307
|
|
| PTS_IIB_glc |
cd00212 |
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: ... |
7-84 |
1.01e-23 |
|
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation
Pssm-ID: 238130 [Multi-domain] Cd Length: 78 Bit Score: 94.52 E-value: 1.01e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446436084 7 KTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPGDVDrVYAELITLAG 84
Cdd:cd00212 2 QLAKDILEALGGKENIVSLDHCATRLRLTVKDESKVDEAALKKLGGVKGVVKNGGQYQVIIGPGVAD-VYKEAIKLLG 78
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTS-IIBC-Tre |
TIGR01992 |
PTS system, trehalose-specific IIBC component; This model represents the fused enzyme II B and ... |
6-470 |
0e+00 |
|
PTS system, trehalose-specific IIBC component; This model represents the fused enzyme II B and C components of the trehalose-specific PTS sugar transporter system. Trehalose is converted to trehalose-6-phosphate in the process of translocation into the cell. These transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci and Streptococci which contain their own A domain as a C-terminal fusion. This family is closely related to the sucrose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively). In E. coli, B. subtilis and P. fluorescens the presence of this gene is associated with the presence of trehalase which degrades T6P to glucose and glucose-6-P. Trehalose may also be transported (in Salmonella) via the mannose PTS or galactose permease systems, or (in Sinorhizobium, Thermococcus and Sulfolobus, for instance) by ABC transporters.
Pssm-ID: 273916 Cd Length: 462 Bit Score: 622.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 6 RKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPGDVDRVYAELITLAGM 85
Cdd:TIGR01992 1 RKDAKAILEAIGGKENIEAATHCVTRLRFVLKDPSKVDVKALEQIDLVKGSFTNAGQFQVVIGPGTVDKVYAALIAETGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 86 EESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDGKNLLDVYPNLGGLWDLINMMA 165
Cdd:TIGR01992 81 AEVSKEEVKKAAAKNMNPLQRLIKLLADIFIPILPAIITAGLLMGINNLLGAKGMSFGGQTLVEVYPQWAGIYNFINLIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 166 NTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGLEgqkIEYFNILGLFQIEKVGYQGQILPVL 245
Cdd:TIGR01992 161 ETAFHFLPALIGWSAVKKFGGSPILGIVLGLMLVHPQLLNAYLYGQALAEGN---IPVWDLFGFFEIQKVGYQGQVLPAL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 246 VAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLFGALYAPLV 325
Cdd:TIGR01992 238 LAGYVLAVIEKWLRKRVPDAIQLLVVPPVSLLVTGFLAHAIIGPIGRLIGNGITSGVTALFTSAAWLGGAIFGLLYAPLV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 326 ITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNLRNKF 405
Cdd:TIGR01992 318 ITGLHHMFLAVDLQLIGSLGGTFLWPMIALSNIAQGSAALGIIFMSRNEKEKGLSLTSAISAYLGVTEPAMFGVNLKYKF 397
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446436084 406 PFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMIIAVVIPFTLTWLFAK 470
Cdd:TIGR01992 398 PFIAAMIGSGLAGLLSGLNGVLANSIGVGGLPGFISIQPQYWPVFAIGMAIAIVVPFVLTIFFSK 462
|
|
| PTS-II-BC-sucr |
TIGR01996 |
PTS system, sucrose-specific IIBC component; This model represents the fused enzyme II B and C ... |
4-468 |
2.95e-179 |
|
PTS system, sucrose-specific IIBC component; This model represents the fused enzyme II B and C components of the sucrose-specific PTS sugar transporter system. Sucrose is converted to sucrose-6-phosphate in the process of translocation into the cell. Some of these transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci, Streptococci, Lactococci, Lactobacilli, etc. which contain their own A domain as a C-terminal fusion. This family is closely related to the trehalose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively).
Pssm-ID: 131051 Cd Length: 461 Bit Score: 509.92 E-value: 2.95e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 4 DYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPGDVDRVYAELITLA 83
Cdd:TIGR01996 1 NYQQVAKEILELLGGKDNIVSVAHCATRLRLVLKDESKIDKKAIENLDGVKGTFFNSGQYQIIIGTGVVNKVYDEIVKLT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 84 GMEESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDgkNLLDVYPNLGGLWDLINM 163
Cdd:TIGR01996 81 GLSESSTSEQKAEAAKKMNPFQRFARTLSDIFVPIIPAIVATGLLMGLNGMLTAFGLFGL--SGVSVAPIPEGLAEMINV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 164 MANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGLEGqkieyFNILGlFQIEKVGYQGQILP 243
Cdd:TIGR01996 159 FTSTAFAFLPILIGFSAAKRFGGNPYLGAVIGLIMVHPSLPNAYGVAAGTATGKA-----WNIFG-LHIPVVGYQGTVLP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 244 VLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLFGALYAP 323
Cdd:TIGR01996 233 VLVAVWILAKIEKFLRKVVPNALDLLLTPFLTLLITGFLTLLVIGPIGRWVGDVLTDGLQWLYDLPGGLGGLLFGGLYSL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 324 LVITGMHHMFIAIDLQLIA--QHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNL 401
Cdd:TIGR01996 313 IVITGIHHSFHAIETQLLAntKTGGNFLFPIASMANVAQGGAALAVFFKTKDKKLKGLAIPSGLSALLGITEPAIFGVNL 392
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446436084 402 RNKFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPM--FIVGMIIAVVIPFTLTWLF 468
Cdd:TIGR01996 393 RYRKPFIAALIGGAIGGAYVVLFHVAATAYGLTGIPGFLSILPSGINLlhYIVGMLIAFAVAFIATLLL 461
|
|
| PRK11007 |
PRK11007 |
PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional |
1-471 |
7.87e-151 |
|
PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional
Pssm-ID: 182896 Cd Length: 473 Bit Score: 437.97 E-value: 7.87e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 1 MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPgDVDRVYAELI 80
Cdd:PRK11007 2 MSKINQQDIDRLIELVGGRENIATVSHCITRLRFVLNDPANADPKEIEQLPMVKGCFTNAGQFQVVIGT-EVGDYYKALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 81 TLAGMEESTVADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGakDL-FFDGKNLLDVYPNLGGLWD 159
Cdd:PRK11007 81 ATTGQAEVDKEQAKKAARQNMKWHERLISHFAEIFFPLLPALISGGLILGFRNVIG--DIpMSDGQTLAQMYPFWQTIYD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 160 LINMMANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKaatglegQKIEYFNiLGLFQIEKVGYQG 239
Cdd:PRK11007 159 FLWLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQ-------QLPEVWD-FGLFSIEKVGYQA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 240 QILPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDlltvglvGVYETV--------PV 311
Cdd:PRK11007 231 QVIPALLAGLALGFIETRLKRIVPDYLYLVVVPVCSLILAVFLAHALIGPFGRMIGD-------GVAFAVkalmtgsfAP 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 312 VGAVLFGALYAPLVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGI 391
Cdd:PRK11007 304 IGAALFGFLYAPLVITGVHQTTLAIDLQMIQSMGGTPVWPLIALSNIAQASAVVGIIIISRKHNEREISVPAAISAYLGV 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 392 TEPAMFGVNLRNKFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMIIAVVIPFTLTWLFAKR 471
Cdd:PRK11007 384 TEPAMYGINLKYRFPMLCAMIGSALAGLICGLNGVMANGIGVGGLPGILSIQPQYWQVYALAMLVAIVVPIVLTSFIYKR 463
|
|
| PtsG1 |
COG1263 |
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific ... |
98-475 |
1.84e-107 |
|
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism];
Pssm-ID: 440875 [Multi-domain] Cd Length: 463 Bit Score: 326.90 E-value: 1.84e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 98 NQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDGknlldvyPNLGGLWDLINMMANTAFVFLPALVG 177
Cdd:COG1263 2 KKKKNPLFRFLQKIGGIFMPPIPVLPAAGLLLGLGALLTNPGLLGEG-------SFLSGTYQILNAAGDAVFYFLPLLFA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 178 WSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKaatglegqkiEYFNILGLFQieKVGYQGQILPVLVAAFVLSKVEIF 257
Cdd:COG1263 75 IGAAKGFGGNPALAAVIGYLLVHPTLLNAYAVAG----------GYISFLGIPT--LIGYQGGVFPGILAGWLAAYLEKF 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 258 LKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLFGALYAPLVITGMHHMFIAID 337
Cdd:COG1263 143 LKKKLPDALGFFFVPILTLLIMVPLALLVIGPIWPPIGNGIAAGLGWIYGLAGAIGGFIYGFLYRLLVPTGLHHGLNPIF 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 338 LQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISK-NQNDKSMASTSAISAYF-GITEPAMFGVNLRNKFPFYAAIIGSA 415
Cdd:COG1263 223 WFLLGGTGDDGLFPILAAAMFGQPGAALAVYLKAKpNKKVKGLAISAALTAFLtGITEPAEFGFNLVAPKLFIAHAIGGG 302
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446436084 416 VAAIFITLNGVLAPAIGIGGLPAFISIIP---KSIPMFIVGMIIAVVIPFTLTWLFAKRVKQK 475
Cdd:COG1263 303 LGGAIAGLLGVKAFSFGVGGLIDFPSILNpgaTNLLLYLIGLVIAFVYYFVFTFLIGREDEEE 365
|
|
| PTS-II-ABC-beta |
TIGR01995 |
PTS system, beta-glucoside-specific IIABC component; This model represents a family of PTS ... |
5-470 |
1.19e-98 |
|
PTS system, beta-glucoside-specific IIABC component; This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.
Pssm-ID: 273919 [Multi-domain] Cd Length: 610 Bit Score: 308.90 E-value: 1.19e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 5 YRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGpGDVDRVYAELITLAG 84
Cdd:TIGR01995 1 YQDLAKAIIENVGGKENIESVTHCATRLRFTLKDDAKADTEKLKKISGVITVVKSGGQYQVVIG-NDVNDVYQALMDVLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 85 MEEstvADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDGKnlldvypnlgGLWDLINMM 164
Cdd:TIGR01995 80 LDD---QAEDDDSKGKKSILNKLIDLISGVFTPLLPALAGAGLLKAVLTLLTMTGLISADS----------QTYQILNAM 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 165 ANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATglegqkieYFNIlglfQIEKVGYQGQILPV 244
Cdd:TIGR01995 147 GDAVFYFLPILLAITAAKRFKVNPYLAAAIGAALLHPTLVAMVGSGKPVT--------FFGI----PVTLMSYSSSVIPV 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 245 LVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLFGALYAPL 324
Cdd:TIGR01995 215 ILAVWLMSYVEKFLKKVIPGALKNFLTPLLVMLITVPLTLLIIGPLGNYAGEGISSGILFLYEVSPWLAGALLAALWPVL 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 325 VITGMHHMFIAIDLQLIAQHG-GTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNLRN 403
Cdd:TIGR01995 295 VMFGLHWAMIPIVINNIATQGfDPLILPASLAANFAQGGAALAVMLRTKNKKLKALAGSATISALFGITEPAIYGVNLPL 374
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446436084 404 KFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMIIAVVIPFTLTWLFAK 470
Cdd:TIGR01995 375 KKPFYAAMIGGAVGGAIIGIGSVKAFTAFAPGLLGLPMFINPSDGANFISALIAIVISFVVSFVLTY 441
|
|
| pts-Glc |
TIGR00852 |
PTS system, maltose and glucose-specific subfamily, IIC component; The PTS Glucose-Glucoside ... |
165-456 |
8.44e-70 |
|
PTS system, maltose and glucose-specific subfamily, IIC component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Glc family includes permeases specific for glucose, N-acetylglucosamine and a large variety of a- and b-glucosides. However, not all b-glucoside PTS permeases are in this class, as the cellobiose (Cel) b-glucoside PTS permease is in the Lac family (TC #4.A.3). These permeases show limited sequence similarity with members of the Fru family (TC #4.A.2). Several of the E. coli PTS permeases in the Glc family lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). Most of these permeases have the B and C domains linked together in a single polypeptide chain, and a cysteyl residue in the IIB domain is phosphorylated by direct phosphoryl transfer from IIAglc(his~P). Those permeases which lack a IIA domain include the maltose (Mal), arbutin-salicin-cellobiose (ASC), trehalose (Tre), putative glucoside (Glv) and sucrose (Scr) permeases of E. coli . Most, but not all Scr permeases of other bacteria also lack a IIA domain. This model is specific for the IIC domain of the Glc family PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Pssm-ID: 273299 Cd Length: 289 Bit Score: 223.73 E-value: 8.44e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 165 ANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGlegqkieyfnILGLFQIEKVGYQGQILPV 244
Cdd:TIGR00852 1 GSAAFFFLPLLFAIGAAKGFGGNPYLGAALAGILVHPVLNNAMGVGAQAVG----------NFFGFEIAKVGYTGVVGPI 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 245 LVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGD-LLTVGLVGVYETVPVVGAVLFGALYAP 323
Cdd:TIGR00852 71 IVGAIALALHERFLDKKLPDVLGFFLGPRFVVIIAGFVAILLIGPLGRVWPPvGISALLHWLYSAGGALGGAIFGFLYRL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 324 LVITGMHHMFIAIDLQLIA---QHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVN 400
Cdd:TIGR00852 151 LVPTGLHHIFYAIFIQLIAggtVIGGGQVIPGDALANMAQGGAALAVFFTAGDAKFKSIGLPAAFSAGLGITEPAMYGVA 230
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 446436084 401 LRNKFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPK---SIPMFIVGMII 456
Cdd:TIGR00852 231 LRERRPFVAGLIGSALLTAFLTGITEPLEFLFLFGAPGLYSIHAVlagSIFTVAIGMGI 289
|
|
| PRK09824 |
PRK09824 |
PTS system beta-glucoside-specific transporter subunits IIABC; Provisional |
4-468 |
2.92e-55 |
|
PTS system beta-glucoside-specific transporter subunits IIABC; Provisional
Pssm-ID: 236627 [Multi-domain] Cd Length: 627 Bit Score: 194.55 E-value: 2.92e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 4 DYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGpGDVDRVYAELITLA 83
Cdd:PRK09824 2 EYTELAREIVAGVGGADNIVSLMHCATRLRFKLKDNSKAQAEVLKKNPGVIMVVESGGQFQVVIG-NHVADVFLAVNSVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 84 GMEEStvADVKDSGNQKLNPAQKFVKIFSDVFMPILPAIVTAGLLMGINNLLGAkdlffdgknlLDVYPNLGGLWDLINM 163
Cdd:PRK09824 81 GLGEK--AQQAPENDKKGNLLNRFIDVISGIFTPLIGVMAATGILKGMLALALT----------FGWTTEQSGTYKILFA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 164 MANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAAtgleGQKIEYFniLGLfQIEKVGYQGQILP 243
Cdd:PRK09824 149 ASDALFFFFPIILGYTAGKKFGGNPFTAMVIGGALVHPLMIAAFEAGQKA----DALGLDF--LGI-PVTLLNYSSSVIP 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 244 VLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLFGALYAP 323
Cdd:PRK09824 222 IIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVIVPLTFLLIGPLATWLSELLAAGYQWLYQAVPAFAGAVMGAFWQV 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 324 LVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNLRN 403
Cdd:PRK09824 302 FVIFGLHWGLVPLMINNLTVLGHDTMLPLLMPAVMAQVGAALGVFLCTRDAQKKVVAGSAFLAGLFGITEPAVYGVNLPL 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 404 KFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIP-----KSIPMFIVGMIIAVVIPFTLTWLF 468
Cdd:PRK09824 382 KRPFIFGCISGALGAAIIGYAQTKVYSFGLPSIFTFMQTIPptgidFTVWASVIGTVIAIGCAFVGTVMF 451
|
|
| PRK09796 |
PRK09796 |
PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional |
1-468 |
2.70e-51 |
|
PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional
Pssm-ID: 182081 Cd Length: 472 Bit Score: 180.76 E-value: 2.70e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 1 MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGpGDVDRVYAELI 80
Cdd:PRK09796 1 MAKNYAALARSVIAALGGVDNISAVTHCMTRLRFVIKDDALIDSPTLKTIPGVLGVVRSDNQCQVIIG-NTVSQAFQEVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 81 TLAGMEESTVADVkdsGNQKLNPAQKFVKIFSDV---FMPILPAIVTAGLLMGINNLLGAKDLFFDGKNLLdvypnlggl 157
Cdd:PRK09796 80 SLLPGDMQPAQPV---GKPKLTLRRIGAGILDALigtMSPLIPAIIGGSMVKLLAMILEMSGVLTKGSPTL--------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 158 wDLINMMANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAwdYGKAAtglEGQKIEYFNIlglfQIEKVGY 237
Cdd:PRK09796 148 -TILNVIGDGAFFFLPLMVAASAAIKFKTNMSLAIAIAGVLVHPSFIEL--MAKAA---QGEHVEFALI----PVTAVKY 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 238 QGQILPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLF 317
Cdd:PRK09796 218 TYTVIPALVMTWCLSYIERWVDRITPAVTKNFLKPMLIVLIAAPLAILLIGPIGIWIGSAISALVYTIHGYLGWLSVAIM 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 318 GALYAPLVITGMHHMFIAIDLQLIAQHGGT-FIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYF-GITEPA 395
Cdd:PRK09796 298 GALWPLLVMTGMHRVFTPTIIQTIAETGKEgMVMPSEIGANLSLGGSSLAVAWKTKNPELRQTALAAAASAIMaGISEPA 377
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446436084 396 MFGVNLRNKFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVG----MIIAVVIPFTLTWLF 468
Cdd:PRK09796 378 LYGVAIRLKRPLIASLISGFICGAVAGMAGLASHSMAAPGLFTSVQFFDPANPMSIVWvfavMALAVVLSFILTLLL 454
|
|
| murP |
PRK09586 |
PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed |
1-471 |
3.80e-46 |
|
PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed
Pssm-ID: 181971 [Multi-domain] Cd Length: 476 Bit Score: 166.78 E-value: 3.80e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 1 MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPGDVDR---VYA 77
Cdd:PRK09586 1 MAKISSELLNTILTRVGGPGNIASCGNCMTRLRLTLHDSSLVDPAAIKTIEGVKGVILSDDQVQVVLGPGKAQRaakAMN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 78 ELITLAGMEESTVADVKDSGNQKLNPAQ-----KFVKIFSDVFMPILPAIVTAGLLMGINNLLGAkdlffdgKNLLDVYP 152
Cdd:PRK09586 81 ELLGEAAAPVQDLAEIAAQNKRQLKAKQtsgvqQFLAKFATIFTPLIPGFIAAGLLLGIATLIEQ-------VMHVPADA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 153 NlGGLWDLINMM---ANTAFVFLPALVGWSATKRFGGSPILGIVMglmlvhpALLNAWDYGKAAT-GLEGQKIEYFNilg 228
Cdd:PRK09586 154 Q-GTLPDALNYMkvfSKGLFTFLSILIGYNAQQAFGGTGVNGAII-------ASLFLLGYNPAATtGYYAGFHDFFG--- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 229 lFQIEKvgyQGQILPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPvtrhIGDLLTVGLVGVYET 308
Cdd:PRK09586 223 -LPIDP---RGNIIGVLIAAIAGARIERMVRRFMPDDLDMILTSLITLLITGALAFLIIMP----LGGWLFEGMSWLFMH 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 309 V---PVVGAVLFGaLYAPLVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWIS-KNQNDKSMASTSA 384
Cdd:PRK09586 295 LnsnPFGCAVLAG-LFLIAVVFGVHQGFIPVYFALMDSQGFNSLFPILAMAGAGQVGAALALYWRAqKHSALRTQVKGAI 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 385 ISAYFGITEPAMFGVNLRNKFPFYAAIIGSAVAAIFITL----------NGVLAPAiGIGGLPAFIS---IIPkSIPMFI 451
Cdd:PRK09586 374 IPGLLGVGEPLIYGVTLPRMKPFVTACLGGAAGGFFIGLiawlglpvglNSVFGPS-GLVALPLMTSaqgILP-GMAVYA 451
|
490 500
....*....|....*....|
gi 446436084 452 VGMIIAVVIPFTLTWLFAKR 471
Cdd:PRK09586 452 GGLLVAYVCGFIFTTLFGCK 471
|
|
| PTS_EIIC |
pfam02378 |
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ... |
112-407 |
2.41e-32 |
|
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.
Pssm-ID: 367061 Cd Length: 315 Bit Score: 125.54 E-value: 2.41e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 112 SDVFMPILPAIVTAGLLMGINNLLGAKDLFFdgknlLDVYPNLGGLWDLINMMANTAFVFLPALVGWSATKRF-GGSPIL 190
Cdd:pfam02378 1 GDGFMPPIPLLIAGGILLGLGNLPNDTTGLP-----AGGFTGDSPLAEILKQAGSAAFGILPILFAIGIAYGLaGGDGVA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 191 GIVMGLMLVHPALLNAWDYGKAATGLEGQKieyfNILGLFQIEKvGYQGQILPVLVAAFVLSKVEIFLKKHVPNAIQLLV 270
Cdd:pfam02378 76 GAAGLIGLLSFNLAAAISVALTAAGLSGGG----NILGIGLGAT-GVFGAIIPGLLAAYLYNRFEKNITIKLPDSLPFFV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 271 VPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVG----VYETVPVVGAVLFGALYAPLVITGMHHMFIAIDLQLIA---- 342
Cdd:pfam02378 151 GKRFVPIITGFVTLLVIGPVLGLIWPAIQGGLNAlgllLIIAGGILGGLIFGFLERLLWPFGLHGAFIAIFWFLPIggsn 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446436084 343 --------QHGGTFIWP---MIALSNIAQGSAAL-AMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNLRNKFPF 407
Cdd:pfam02378 231 pianqqayGAGAAHILTggfDVMFGGPGATLALYaAAFLFKKSKVKKLLGSAALTPFLFGITEPLEFGFPFVLNPPF 307
|
|
| PtsG2 |
COG1264 |
Phosphotransferase system IIB components [Carbohydrate transport and metabolism]; |
6-82 |
3.20e-24 |
|
Phosphotransferase system IIB components [Carbohydrate transport and metabolism];
Pssm-ID: 440876 [Multi-domain] Cd Length: 76 Bit Score: 95.57 E-value: 3.20e-24
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446436084 6 RKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSlVKGAFHNAGIFQVVIGPGdVDRVYAELITL 82
Cdd:COG1264 1 KELAKDILEALGGKENIVSVDHCATRLRVTVKDPSKVDEAALKKLG-VKGVVKNGGQVQVIIGPG-VDKVADEIEKL 75
|
|
| PTS_IIB_glc |
cd00212 |
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: ... |
7-84 |
1.01e-23 |
|
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation
Pssm-ID: 238130 [Multi-domain] Cd Length: 78 Bit Score: 94.52 E-value: 1.01e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446436084 7 KTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPGDVDrVYAELITLAG 84
Cdd:cd00212 2 QLAKDILEALGGKENIVSLDHCATRLRLTVKDESKVDEAALKKLGGVKGVVKNGGQYQVIIGPGVAD-VYKEAIKLLG 78
|
|
| EIIB_glc |
TIGR00826 |
PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) ... |
30-113 |
3.73e-16 |
|
PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Glc family includes permeases specific for glucose, N-acetylglucosamine and a large variety of a- and b-glucosides. However, not all b-glucoside PTS permeases are in this class, as the cellobiose (Cel) b-glucoside PTS permease is in the Lac family (TC #4.A.3). These permeases show limited sequence similarity with members of the Fru family (TC #4.A.2). Several of the E. coli PTS permeases in the Glc family lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). Most of these permeases have the B and C domains linked together in a single polypeptide chain, and a cysteyl residue in the IIB domain is phosphorylated by direct phosphoryl transfer from IIAglc(his~P). Those permeases which lack a IIA domain include the maltose (Mal), arbutin-salicin-cellobiose (ASC), trehalose (Tre), putative glucoside (Glv) and sucrose (Scr) permeases of E. coli . Most, but not all Scr permeases of other bacteria also lack a IIA domain. This model is specific for the IIB domain of the Glc family PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Pssm-ID: 273288 [Multi-domain] Cd Length: 88 Bit Score: 73.55 E-value: 3.73e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 30 TRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPGDVDRVYAELITL-AGMEEST---VADVKDSGNQKLNPAQ 105
Cdd:TIGR00826 1 TRLRLKTPGREKADEEAIAAGEGVKGVFTAAGQIQALGGTGNVNKVDACITRLrVGVADVSkvdDAVLKKLGAHGVNPLQ 80
|
....*...
gi 446436084 106 KFVKIFSD 113
Cdd:TIGR00826 81 RAVQVISG 88
|
|
| PRK14905 |
PRK14905 |
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; ... |
5-82 |
1.80e-14 |
|
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; Provisional
Pssm-ID: 184898 [Multi-domain] Cd Length: 355 Bit Score: 74.68 E-value: 1.80e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446436084 5 YRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIGPGDVDRVYAELITL 82
Cdd:PRK14905 274 FSEIAIQLIDHLGGKDNISALTHCASRIRVMLRNDGHIDKSAIEKIDCVKGLFSIANQYQIILGAGIVEKIHEEMKAL 351
|
|
| PTS_EIIB |
pfam00367 |
phosphotransferase system, EIIB; |
10-41 |
6.68e-12 |
|
phosphotransferase system, EIIB;
Pssm-ID: 459785 [Multi-domain] Cd Length: 32 Bit Score: 59.69 E-value: 6.68e-12
10 20 30
....*....|....*....|....*....|..
gi 446436084 10 EEVLQYIGGKDNIEQAAHCVTRLRIALKDESK 41
Cdd:pfam00367 1 KEILEALGGKENIKSVDHCATRLRLTVKDESK 32
|
|
| EIIB_glc |
TIGR00826 |
PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) ... |
8-68 |
1.55e-07 |
|
PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Glc family includes permeases specific for glucose, N-acetylglucosamine and a large variety of a- and b-glucosides. However, not all b-glucoside PTS permeases are in this class, as the cellobiose (Cel) b-glucoside PTS permease is in the Lac family (TC #4.A.3). These permeases show limited sequence similarity with members of the Fru family (TC #4.A.2). Several of the E. coli PTS permeases in the Glc family lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). Most of these permeases have the B and C domains linked together in a single polypeptide chain, and a cysteyl residue in the IIB domain is phosphorylated by direct phosphoryl transfer from IIAglc(his~P). Those permeases which lack a IIA domain include the maltose (Mal), arbutin-salicin-cellobiose (ASC), trehalose (Tre), putative glucoside (Glv) and sucrose (Scr) permeases of E. coli . Most, but not all Scr permeases of other bacteria also lack a IIA domain. This model is specific for the IIB domain of the Glc family PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Pssm-ID: 273288 [Multi-domain] Cd Length: 88 Bit Score: 48.89 E-value: 1.55e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446436084 8 TAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSlVKGAFHNAGIFQVVIG 68
Cdd:TIGR00826 29 TAAGQIQALGGTGNVNKVDACITRLRVGVADVSKVDDAVLKKLG-AHGVNPLQRAVQVISG 88
|
|
| PRK10110 |
PRK10110 |
PTS maltose transporter subunit IICB; |
9-84 |
1.16e-05 |
|
PTS maltose transporter subunit IICB;
Pssm-ID: 182245 [Multi-domain] Cd Length: 530 Bit Score: 47.80 E-value: 1.16e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446436084 9 AEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQ---SVSLVKGAFHNagiFQVVIGPgDVDRVYAELITLAG 84
Cdd:PRK10110 452 VPAILEALGGADNIVSLDNCITRLRLSVKDMSLVDVQALKdnrAIGVVQLNQHN---LQVVIGP-QVQSVKDEMAGLMH 526
|
|
| FrwC |
COG1299 |
Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and ... |
245-475 |
1.51e-05 |
|
Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism];
Pssm-ID: 440910 [Multi-domain] Cd Length: 469 Bit Score: 47.19 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 245 LVAAFVLSKVEIFLKKH--VPNAIQ----LLVVPITTIVVTGVLALGIIGPVTRHIGDLLTVGLVGVYETvpvvGAVLFG 318
Cdd:COG1299 229 IIAGFLAGYVVLWLKKKikLPKSLEglkpILIIPLLGTLITGLLMIYVIGPPIAALNTALTNWLNSMSGS----NAVLLG 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 319 AlyaplVITGMhhmfIAIDL-------------QLIAQHGGTfiwPMIALsNIAQGSAALAMF---WISKN---QNDKSM 379
Cdd:COG1299 305 A-----ILGAM----MAFDMggpvnkaayafgtGLLASGIYA---PMAAV-MAAGMVPPLGLAlatLLFKKkftEEEREA 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 380 ASTSAISAYFGITEPAMfgvnlrnkfPFYAA---------IIGSAVAAIFITLNGVLAPAiGIGGLpaFISIIPKSIPMF 450
Cdd:COG1299 372 GKAAFILGLSFITEGAI---------PFAAAdplrvipsnMIGSAVAGALSMLFGVTLPA-PHGGI--FVLPLVSNPLLY 439
|
250 260
....*....|....*....|....*
gi 446436084 451 IVGMIIAVVIPFTLTWLFAKRVKQK 475
Cdd:COG1299 440 LLAIAIGTVVTALLLGLLKKPVEKK 464
|
|
| PRK09702 |
PRK09702 |
PTS sugar transporter subunit IIB; |
9-68 |
2.60e-05 |
|
PTS sugar transporter subunit IIB;
Pssm-ID: 77355 [Multi-domain] Cd Length: 161 Bit Score: 44.32 E-value: 2.60e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 9 AEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGIFQVVIG 68
Cdd:PRK09702 73 AAGILQALGGVGNISSINNCATRLRIALHDMSQTLDDEVFKKLGAHGVFRSGDAIQVIIG 132
|
|
| PRK11089 |
PRK11089 |
PTS system glucose-specific transporter subunits IIBC; Provisional |
8-70 |
3.99e-04 |
|
PTS system glucose-specific transporter subunits IIBC; Provisional
Pssm-ID: 182955 [Multi-domain] Cd Length: 477 Bit Score: 42.78 E-value: 3.99e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446436084 8 TAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVslvkGAfhnAGIfqVVIGPG 70
Cdd:PRK11089 401 MAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKL----GA---AGV--VVAGSG 454
|
|
| PTS_EIIC_2 |
pfam13303 |
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ... |
239-475 |
4.42e-03 |
|
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.
Pssm-ID: 433101 Cd Length: 327 Bit Score: 39.10 E-value: 4.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 239 GQILPVLVAAFVLSKVeIFLKKHVPNAIQLLVVPITTIVVTGVLALgIIGPVTRHIGDLLTVGLVGVYETVPVVGAVLFG 318
Cdd:pfam13303 91 GDPINAFLAAAIAVLV-GKLIGNKKTKLDIIVLPIVVIVVGGLIGL-LILPYVKPITEAIGNVINTATDLQPLIMGILIA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 319 ALYAPLVITGMHHMFIAIdlqliaqhggtfiwpMIALSNIAQGSAALA-------MFWISKNQNDKSmaSTSAIsayfGI 391
Cdd:pfam13303 169 VIFGILITSPISSAAIAI---------------ALGLTGLASGAAAIGcaaqmvgLAVASLKVNGFG--GTLAV----GL 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446436084 392 TEPAMFGVN-LRNKFPFYAAIIGSAVAAIFITLNGVLAPAI----GIGGLPAFISIIPKSIPMFIVGMIIA-VVIPFTLT 465
Cdd:pfam13303 228 GTPKLQMPNiLKNPIILIPPLLAGAISGPVAAIFGLQGTPAsagfGTSGLVGPLAALTGTGWSTVLIIILVyFVLPAVLG 307
|
250
....*....|
gi 446436084 466 WLFAKRVKQK 475
Cdd:pfam13303 308 LLISKLFKKL 317
|
|
| |
