|
Name |
Accession |
Description |
Interval |
E-value |
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
4-318 |
1.25e-157 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 443.73 E-value: 1.25e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQfDDGNISFESKDLTNLQESE 83
Cdd:COG0444 1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPGI-TSGEILFDGEDLLKLSEKE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQYPHQLSGGMRQRI 163
Cdd:COG0444 80 LRKIRGREIQMIFQDPMTSLNPVMTVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDPERRLDRYPHELSGGMRQRV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:COG0444 160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELF 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 244 GSPKHPYTKSLLQAIPNMDDAEKVLRAIEGTTPSIETLNSfGCPFVNRCPVAIQECIHRFPERTTYSAEHSSHCW 318
Cdd:COG0444 240 ENPRHPYTRALLSSIPRLDPDGRRLIPIPGEPPSLLNPPS-GCRFHPRCPYAMDRCREEEPPLREVGPGHRVACH 313
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
4-270 |
6.74e-132 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 386.35 E-value: 6.74e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDDGNISFESKDLTNLQESE 83
Cdd:COG4172 6 LLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPDPAAHPSGSILFDGQDLLGLSERE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQYPHQLSGGMRQRI 163
Cdd:COG4172 86 LRRIRGNRIAMIFQEPMTSLNPLHTIGKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLDAYPHQLSGGQRQRV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:COG4172 166 MIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAELF 245
|
250 260 270
....*....|....*....|....*....|...
gi 446453403 244 GSPKHPYTKSLLQAIPNMD------DAEKVLRA 270
Cdd:COG4172 246 AAPQHPYTRKLLAAEPRGDprpvppDAPPLLEA 278
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
4-237 |
1.51e-108 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 315.98 E-value: 1.51e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQEsE 83
Cdd:cd03257 1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKP----TSGSIIFDGKDLLKLSR-R 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAInLLNDLGIHEAEKRFEQYPHQLSGGMRQRI 163
Cdd:cd03257 76 LRKIRRKEIQMVFQDPMSSLNPRMTIGEQIAEPLRIHGKLSKKEARKEAV-LLLLVGVGLPEEVLNRYPHELSGGQRQRV 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03257 155 AIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
24-323 |
1.15e-105 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 312.43 E-value: 1.15e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGL---NQESiqfdDGNISFESKDLTNLQESEWNQIRGKDISFIFQDPL 100
Cdd:PRK09473 32 VNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLlaaNGRI----GGSATFNGREILNLPEKELNKLRAEQISMIFQDPM 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 SSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADE 180
Cdd:PRK09473 108 TSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADE 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 181 PTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLLQAIPN 260
Cdd:PRK09473 188 PTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPSHPYSIGLLNAVPR 267
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 261 MDDAEKVLRAIEGTTPSIETLNSfGCPFVNRCPVAIQECiHRFPERTTYSAEHSSHCWQHVLE 323
Cdd:PRK09473 268 LDAEGESLLTIPGNPPNLLRLPK-GCPFQPRCPHAMEIC-SSAPPLEEFGPGRLRACFKPVEE 328
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
4-262 |
2.41e-101 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 307.60 E-value: 2.41e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLA-VEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQES 82
Cdd:COG1123 260 LLEVRNLSKRyPVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGL----LRPTSGSILFDGKDLTKLSRR 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNQIRgKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAekRFEQYPHQLSGGMRQR 162
Cdd:COG1123 336 SLRELR-RRVQMVFQDPYSSLNPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPD--LADRYPHELSGGQRQR 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:COG1123 413 VAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEV 492
|
250 260
....*....|....*....|
gi 446453403 243 IGSPKHPYTKSLLQAIPNMD 262
Cdd:COG1123 493 FANPQHPYTRALLAAVPSLD 512
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
24-318 |
3.88e-96 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 287.78 E-value: 3.88e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEWNQIRgKDISFIFQDPLSSL 103
Cdd:COG4608 34 VDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRL----EEPTSGEILFDGQDITGLSGRELRPLR-RRMQMVFQDPYASL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAekRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTT 183
Cdd:COG4608 109 NPRMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPE--HADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVS 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 184 ALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLLQAIPNMDD 263
Cdd:COG4608 187 ALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPRDELYARPLHPYTQALLSAVPVPDP 266
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 264 AEKVLRAI-EGTTPSieTLN--SfGCPFVNRCPVAIQECIHRFPERTTYSAEHSSHCW 318
Cdd:COG4608 267 ERRRERIVlEGDVPS--PLNppS-GCRFHTRCPYAQDRCATEEPPLREVGPGHQVACH 321
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
4-305 |
5.14e-96 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 287.79 E-value: 5.14e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDDGNISFESKDLTNLQESE 83
Cdd:PRK11022 3 LLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQYPHQLSGGMRQRI 163
Cdd:PRK11022 83 RRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQRV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK11022 163 MIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIF 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446453403 244 GSPKHPYTKSLLQAIPNMDDAEKVLRAIEGTTPSIETLNSfGCPFVNRCPVAIQECIHRFPE 305
Cdd:PRK11022 243 RAPRHPYTQALLRALPEFAQDKARLASLPGVVPGKYDRPN-GCLLNPRCPYATDRCRAEEPA 303
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-278 |
3.55e-90 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 278.71 E-value: 3.55e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTlaVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDdGNISFESKDLTNLQ 80
Cdd:COG1123 1 MTPLLEVRDLS--VRYPGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGRIS-GEVLLDGRDLLELS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 EsewnQIRGKDISFIFQDPLSSLNPTmKVGRQITEViLQHEKKSKKEAKEIAINLLNDLGIheaEKRFEQYPHQLSGGMR 160
Cdd:COG1123 78 E----ALRGRRIGMVFQDPMTQLNPV-TVGDQIAEA-LENLGLSRAEARARVLELLEAVGL---ERRLDRYPHQLSGGQR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQ 240
Cdd:COG1123 149 QRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPE 228
|
250 260 270
....*....|....*....|....*....|....*...
gi 446453403 241 EVIGSPKhpytksLLQAIPNMDDAEKVLRAIEGTTPSI 278
Cdd:COG1123 229 EILAAPQ------ALAAVPRLGAARGRAAPAAAAAEPL 260
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
4-259 |
4.65e-85 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 256.65 E-value: 4.65e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQESE 83
Cdd:COG1124 1 MLEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERP----WSGEVTFDGRPVTRRRRKA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNqirgKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAkeiAINLLNDLGIHEAEKRfeQYPHQLSGGMRQRI 163
Cdd:COG1124 77 FR----RRVQMVFQDPYASLHPRHTVDRILAEPLRIHGLPDREER---IAELLEQVGLPPSFLD--RYPHQLSGGQRQRV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:COG1124 148 AIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLL 227
|
250
....*....|....*.
gi 446453403 244 GSPKHPYTKSLLQAIP 259
Cdd:COG1124 228 AGPKHPYTRELLAASL 243
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
3-317 |
5.61e-85 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 259.45 E-value: 5.61e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 3 QLLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDDGNISFESKDLTNLQES 82
Cdd:COG4170 2 PLLDIRNLTIEIDTPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNWHVTADRFRWNGIDLLKLSPR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSK-----KEAKEIAINLLNDLGIHEAEKRFEQYPHQLSG 157
Cdd:COG4170 82 ERRKIIGREIAMIFQEPSSCLDPSAKIGDQLIEAIPSWTFKGKwwqrfKWRKKRAIELLHRVGIKDHKDIMNSYPHELTE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 158 GMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:COG4170 162 GECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 238 TIQEVIGSPKHPYTKSLLQAIPNMDD--AEKV-LRAIEGTTPSIETLnSFGCPFVNRCPVAIQECIHRfPERTTYSaEHS 314
Cdd:COG4170 242 PTEQILKSPHHPYTKALLRSMPDFRQplPHKSrLNTLPGSIPPLQHL-PIGCRLGPRCPYAQKKCVET-PRLRKIK-GHE 318
|
...
gi 446453403 315 SHC 317
Cdd:COG4170 319 FAC 321
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
24-262 |
1.58e-82 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 259.62 E-value: 1.58e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnQESiqfdDGNISFESKDLTNLQESEWNQIRgKDISFIFQDPLSSL 103
Cdd:COG4172 302 VDGVSLTLRRGETLGLVGESGSGKSTLGLALLRL-IPS----EGEIRFDGQDLDGLSRRALRPLR-RRMQVVFQDPFGSL 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITE-VILQHEKKSKKEAKEIAINLLNDLGIHEAekRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPT 182
Cdd:COG4172 376 SPRMTVGQIIAEgLRVHGPGLSAAERRARVAEALEEVGLDPA--ARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPT 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 183 TALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLLQAIPNMD 262
Cdd:COG4172 454 SALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYTRALLAAAPLLE 533
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
4-259 |
1.98e-81 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 256.56 E-value: 1.98e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGL-NQESIQFDDGNISFESKDLTNLQES 82
Cdd:PRK15134 5 LLAIENLSVAFRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLlPSPPVVYPSGDIRFHGESLLHASEQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQYPHQLSGGMRQR 162
Cdd:PRK15134 85 TLRGVRGNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGGERQR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK15134 165 VMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATL 244
|
250
....*....|....*..
gi 446453403 243 IGSPKHPYTKSLLQAIP 259
Cdd:PRK15134 245 FSAPTHPYTQKLLNSEP 261
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
24-317 |
4.89e-80 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 246.93 E-value: 4.89e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEWNQIRgKDISFIFQDPLSSL 103
Cdd:PRK15079 37 VDGVTLRLYEGETLGVVGESGCGKSTFARAIIGL----VKATDGEVAWLGKDLLGMKDDEWRAVR-SDIQMIFQDPLASL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITEVILQHEKKSKKEAKEIAI-----------NLLNdlgiheaekrfeQYPHQLSGGMRQRICLAIAFACH 172
Cdd:PRK15079 112 NPRMTIGEIIAEPLRTYHPKLSRQEVKDRVkammlkvgllpNLIN------------RYPHEFSGGQCQRIGIARALILE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 173 PKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTK 252
Cdd:PRK15079 180 PKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTK 259
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 253 SLLQAIPNMD-DAE--KVLRAIEGTTPSIETLNSfGCPFVNRCPVAIQECIHRFPERTTySAEHSSHC 317
Cdd:PRK15079 260 ALMSAVPIPDpDLErnKTIQLLEGELPSPINPPS-GCVFRTRCPIAGPECAKTRPVLEG-SFRHAVSC 325
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
2-261 |
4.53e-76 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 245.15 E-value: 4.53e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 2 GQLLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESK------- 74
Cdd:PRK10261 10 RDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQA----GGLVQCDKMllrrrsr 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 75 ---DLTNLQESEWNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQY 151
Cdd:PRK10261 86 qviELSEQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTILSRY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 152 PHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGG 231
Cdd:PRK10261 166 PHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQG 245
|
250 260 270
....*....|....*....|....*....|
gi 446453403 232 RIVEKGTIQEVIGSPKHPYTKSLLQAIPNM 261
Cdd:PRK10261 246 EAVETGSVEQIFHAPQHPYTRALLAAVPQL 275
|
|
| nickel_nikD |
TIGR02770 |
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ... |
23-257 |
1.74e-72 |
|
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131817 [Multi-domain] Cd Length: 230 Bit Score: 224.17 E-value: 1.74e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDDGNISFESKDLTNLQesewnqIRGKDISFIFQDPLSS 102
Cdd:TIGR02770 1 LVQDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQTSGEILLDGRPLLPLS------IRGRHIATIMQNPRTA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 103 LNPTMKVGRQITEVILQHEKKSKKEAKEIAiNLLNDLGIHEAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPT 182
Cdd:TIGR02770 75 FNPLFTMGNHAIETLRSLGKLSKQARALIL-EALEAVGLPDPEEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPT 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 183 TALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLLQA 257
Cdd:TIGR02770 154 TDLDVVNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLSA 228
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
4-300 |
2.53e-69 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 219.67 E-value: 2.53e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDDGNISFESKDLTNLQESE 83
Cdd:PRK15093 3 LLDIRNLTIEFKTSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSPRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVI-----LQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQYPHQLSGG 158
Cdd:PRK15093 83 RRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIpgwtyKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELTEG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 159 MRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGT 238
Cdd:PRK15093 163 ECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAP 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 239 IQEVIGSPKHPYTKSLLQAIPNMDDA---EKVLRAIEGTTPSIETLnSFGCPFVNRCPVAIQECI 300
Cdd:PRK15093 243 SKELVTTPHHPYTQALIRAIPDFGSAmphKSRLNTLPGAIPLLEHL-PIGCRLGPRCPYAQRECI 306
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
27-299 |
4.84e-64 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 205.58 E-value: 4.84e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEWNQIRgKDISFIFQDPLSSLNPT 106
Cdd:PRK11308 34 VSFTLERGKTLAVVGESGCGKSTLARLLTMIETPT----GGELYYQGQDLLKADPEAQKLLR-QKIQIVFQNPYGSLNPR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 107 MKVGRQITEvilqhekkskkeakEIAINllNDLGIHE-AEK----------RFEQ---YPHQLSGGMRQRICLAIAFACH 172
Cdd:PRK11308 109 KKVGQILEE--------------PLLIN--TSLSAAErREKalammakvglRPEHydrYPHMFSGGQRQRIAIARALMLD 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 173 PKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTK 252
Cdd:PRK11308 173 PDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNPRHPYTQ 252
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 446453403 253 SLLQAIPNMD-DAEKVLRAIEGTTPSieTLN-SFGCPFVNRCPVAIQEC 299
Cdd:PRK11308 253 ALLSATPRLNpDDRRERIKLTGELPS--PLNpPPGCAFNARCPRAFGRC 299
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
5-233 |
2.64e-58 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 187.31 E-value: 2.64e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSIIGLNQESiqfDDGNISFESKDLTNLQESEW 84
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKS-TLLNILGGLDRP---TSGEVRVDGTDISKLSEKEL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRGKDISFIFQDPlsSLNPTMKVGRQItEVILQHEKKSKKEAKEIAINLLNDLGIheaEKRFEQYPHQLSGGMRQRIC 164
Cdd:cd03255 77 AAFRRRHIGFVFQSF--NLLPDLTALENV-ELPLLLAGVPKKERRERAEELLERVGL---GDRLNHYPSELSGGQQQRVA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREvADRVVVMYGGRI 233
Cdd:cd03255 151 IARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDGKI 218
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-235 |
2.94e-57 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 184.86 E-value: 2.94e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSIIGLNQesiQFDDGNISFESKDLTNLQ 80
Cdd:COG1136 1 MSPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKS-TLLNILGGLD---RPTSGEVLIDGQDISSLS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 ESEWNQIRGKDISFIFQDPlsSLNPTMKVGRQItEVILQHEKKSKKEAKEIAINLLNDLGIheaEKRFEQYPHQLSGGMR 160
Cdd:COG1136 77 ERELARLRRRHIGFVFQFF--NLLPELTALENV-ALPLLLAGVSRKERRERARELLERVGL---GDRLDHRPSQLSGGQQ 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVrEVADRVVVMYGGRIVE 235
Cdd:COG1136 151 QRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELA-ARADRVIRLRDGRIVS 224
|
|
| SapF |
COG4167 |
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms]; |
20-257 |
1.35e-54 |
|
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 179.26 E-value: 1.35e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 20 KQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLtnlqESEWNQIRGKDISFIFQDP 99
Cdd:COG4167 25 QFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPT----SGEILINGHKL----EYGDYKYRCKHIRMIFQDP 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 LSSLNPTMKVGrQITEVILQhekkskkeakeiainLLNDLGIHEAEKRFEQ--------------YPHQLSGGMRQRICL 165
Cdd:COG4167 97 NTSLNPRLNIG-QILEEPLR---------------LNTDLTAEEREERIFAtlrlvgllpehanfYPHMLSSGQKQRVAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 166 AIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGS 245
Cdd:COG4167 161 ARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVFAN 240
|
250
....*....|..
gi 446453403 246 PKHPYTKSLLQA 257
Cdd:COG4167 241 PQHEVTKRLIES 252
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
24-264 |
2.90e-54 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 187.37 E-value: 2.90e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEWNQIRgKDISFIFQDPLSSL 103
Cdd:PRK10261 340 VEKVSFDLWPGETLSLVGESGSGKSTTGRALLRL----VESQGGEIIFNGQRIDTLSPGKLQALR-RDIQFIFQDPYASL 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTT 183
Cdd:PRK10261 415 DPRQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPEHAW--RYPHEFSGGQRQRICIARALALNPKVIIADEAVS 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 184 ALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLLQAIPNMDD 263
Cdd:PRK10261 493 ALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLMAAVPVADP 572
|
.
gi 446453403 264 A 264
Cdd:PRK10261 573 S 573
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
4-258 |
2.11e-52 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 173.72 E-value: 2.11e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENV-----TLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTN 78
Cdd:PRK10419 3 LLNVSGLshhyaHGGLSGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESP----SQGNVSWRGEPLAK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 79 LQESEWNQIRgKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLN--DLGIHEAEKRfeqyPHQLS 156
Cdd:PRK10419 79 LNRAQRKAFR-RDIQMVFQDSISAVNPRKTVREIIREPLRHLLSLDKAERLARASEMLRavDLDDSVLDKR----PPQLS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 157 GGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEK 236
Cdd:PRK10419 154 GGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVET 233
|
250 260
....*....|....*....|..
gi 446453403 237 GTIQEVIGSpKHPYTKSLLQAI 258
Cdd:PRK10419 234 QPVGDKLTF-SSPAGRVLQNAV 254
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
4-255 |
6.95e-52 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 171.70 E-value: 6.95e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESE 83
Cdd:COG1127 5 MIEVRNLTKSFGD----RVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGL----LRPDSGEILVDGQDITGLSEKE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRgKDISFIFQDP--LSSLNptmkVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMRQ 161
Cdd:COG1127 77 LYELR-RRIGMLFQGGalFDSLT----VFENVAFPLREHTDLSEAEIRELVLEKLELVGLPGAADK---MPSELSGGMRK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 162 RICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQE 241
Cdd:COG1127 149 RVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEE 228
|
250
....*....|....
gi 446453403 242 VIGSPkHPYTKSLL 255
Cdd:COG1127 229 LLASD-DPWVRQFL 241
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
1-257 |
2.23e-50 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 168.34 E-value: 2.23e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLAvekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDDGNIsfeskdLTNLQ 80
Cdd:PRK10418 1 MPQQIELRNIALQ-----AAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAGVRQTAGRV------LLDGK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 ESEWNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVILQhekKSKKEAKEIAINLLNDLGIHEAEKRFEQYPHQLSGGMR 160
Cdd:PRK10418 70 PVAPCALRGRKIATIMQNPRSAFNPLHTMHTHARETCLA---LGKPADDATLTAALEAVGLENAARVLKLYPFEMSGGML 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQ 240
Cdd:PRK10418 147 QRMMIALALLCEAPFIIADEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVE 226
|
250
....*....|....*..
gi 446453403 241 EVIGSPKHPYTKSLLQA 257
Cdd:PRK10418 227 TLFNAPKHAVTRSLVSA 243
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
20-258 |
2.54e-50 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 168.45 E-value: 2.54e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 20 KQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEWNQIRgKDISFIFQDP 99
Cdd:TIGR02769 23 RAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPA----QGTVSFRGQDLYQLDRKQRRAFR-RDVQLVFQDS 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 LSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeQYPHQLSGGMRQRICLAIAFACHPKLVIAD 179
Cdd:TIGR02769 98 PSAVNPRMTVRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRSEDAD--KLPRQLSGGQLQRINIARALAVKPKLIVLD 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 180 EPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIgSPKHPYTKSLLQAI 258
Cdd:TIGR02769 176 EAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQLL-SFKHPAGRNLQSAV 253
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
5-271 |
6.55e-50 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 169.49 E-value: 6.55e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQesiqFDDGNISFESKDLTNLQESEW 84
Cdd:COG1135 2 IELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLER----PTSGSVLVDGVDLTALSEREL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRgKDISFIFQDP--LSSLN-------PtMKV----GRQITEVILQhekkskkeakeiainLLNDLGIheAEKRfEQY 151
Cdd:COG1135 78 RAAR-RKIGMIFQHFnlLSSRTvaenvalP-LEIagvpKAEIRKRVAE---------------LLELVGL--SDKA-DAY 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 152 PHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGG 231
Cdd:COG1135 138 PSQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENG 217
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 446453403 232 RIVEKGTIQEVIGSPKHPYTKSLLQAIPNMDDAEKVLRAI 271
Cdd:COG1135 218 RIVEQGPVLDVFANPQSELTRRFLPTVLNDELPEELLARL 257
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
5-253 |
3.41e-49 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 164.60 E-value: 3.41e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:cd03261 1 IELRGLTKSFGG----RTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGL----LRPDSGEVLIDGEDISGLSEAEL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRgKDISFIFQDP--LSSLNptmkVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKrfeQYPHQLSGGMRQR 162
Cdd:cd03261 73 YRLR-RRMGMLFQSGalFDSLT----VFENVAFPLREHTRLSEEEIREIVLEKLEAVGLRGAED---LYPAELSGGMKKR 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:cd03261 145 VALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
|
250
....*....|.
gi 446453403 243 IGSPkHPYTKS 253
Cdd:cd03261 225 RASD-DPLVRQ 234
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
5-243 |
1.90e-48 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 162.12 E-value: 1.90e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENskqEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEw 84
Cdd:COG1122 1 IELENLSFSYPGGT---PALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGL----LKPTSGEVLVDGKDITKKNLRE- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqIRgKDISFIFQDPLSSL-NPT-----------MKVGRQitEVilqhekkskkeaKEIAINLLNDLGIHEAEKRfeqYP 152
Cdd:COG1122 73 --LR-RKVGLVFQNPDDQLfAPTveedvafgpenLGLPRE--EI------------RERVEEALELVGLEHLADR---PP 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 153 HQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGR 232
Cdd:COG1122 133 HELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLN-KEGKTVIIVTHDLDLVAELADRVIVLDDGR 211
|
250
....*....|.
gi 446453403 233 IVEKGTIQEVI 243
Cdd:COG1122 212 IVADGTPREVF 222
|
|
| PhnK |
COG4107 |
ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and ... |
4-258 |
4.02e-48 |
|
ABC-type phosphonate transport system, ATPase component PhnK [Inorganic ion transport and metabolism];
Pssm-ID: 443283 [Multi-domain] Cd Length: 262 Bit Score: 162.67 E-value: 4.02e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESK-----DLTN 78
Cdd:COG4107 8 LLSVRGLSKRYGPGCGTVVACRDVSFDLYPGEVLGIVGESGSGKSTLLKCLYF----DLAPTSGSVYYRDRdggprDLFA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 79 LQESEWNQIRGKDISFIFQDPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAekRFEQYPHQLSGG 158
Cdd:COG4107 84 LSEAERRRLRRTDWGMVYQNPRDGLRMDVSAGGNIAERLMAAGERHYGDIRARALEWLERVEIPLE--RIDDLPRTFSGG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 159 MRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGT 238
Cdd:COG4107 162 MQQRVQIARALVTNPRLLFLDEPTTGLDVSVQARLLDLIRRLQRELGLSMIVVTHDLGVIRLLADRTMVMKNGRVVESGL 241
|
250 260
....*....|....*....|
gi 446453403 239 IQEVIGSPKHPYTKSLLQAI 258
Cdd:COG4107 242 TDQVLEDPQHPYTQLLVSSV 261
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
23-256 |
1.03e-46 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 165.65 E-value: 1.03e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfddGNISFESKDLTNLQESEWNQIRGKdISFIFQDPLSS 102
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLINSQ-----GEIWFDGQPLHNLNRRQLLPVRHR-IQVVFQDPNSS 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 103 LNPTMKVgRQITEVILQ--HEKKSKKEAKEIAINLLNDLGIhEAEKRFeQYPHQLSGGMRQRICLAIAFACHPKLVIADE 180
Cdd:PRK15134 375 LNPRLNV-LQIIEEGLRvhQPTLSAAQREQQVIAVMEEVGL-DPETRH-RYPAEFSGGQRQRIAIARALILKPSLIILDE 451
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 181 PTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLLQ 256
Cdd:PRK15134 452 PTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYTRQLLA 527
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
6-232 |
1.61e-46 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 156.86 E-value: 1.61e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 6 SLENVTLAVEkeNSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTnlqESEWN 85
Cdd:cd03225 1 ELKNLSFSYP--DGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPT----SGEVLVDGKDLT---KLSLK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 86 QIRGKdISFIFQDPLSSL-NPTmkVGRqitEVI--LQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMRQR 162
Cdd:cd03225 72 ELRRK-VGLVFQNPDDQFfGPT--VEE---EVAfgLENLGLPEEEIEERVEEALELVGLEGLRDR---SPFTLSGGQKQR 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGR 232
Cdd:cd03225 143 VAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKA-EGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
5-243 |
2.77e-46 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 156.76 E-value: 2.77e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTnlqeSEW 84
Cdd:COG1131 1 IEVRGLT----KRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGL----LRPTSGEVRVLGEDVA----RDP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRgKDISFIFQDPlsSLNPTMKVgRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMRQRIC 164
Cdd:COG1131 69 AEVR-RRIGYVPQEP--ALYPDLTV-RENLRFFARLYGLPRKEARERIDELLELFGLTDAADR---KVGTLSGGMKQRLG 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:COG1131 142 LALALLHDPELLILDEPTSGLDPEARRELWELLRELAA-EGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELK 219
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
4-258 |
1.13e-45 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 155.54 E-value: 1.13e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTnLQESE 83
Cdd:COG1126 1 MIEIENLH----KSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLL----EEPDSGTITVDGEDLT-DSKKD 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRgKDISFIFQdplsSLN--PTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIheAEKRfEQYPHQLSGGMRQ 161
Cdd:COG1126 72 INKLR-RKVGMVFQ----QFNlfPHLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGL--ADKA-DAYPAQLSGGQQQ 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 162 RICLAIAFACHPKLVIADEPTTALD------VTiqkQIMGLLKerkeKQNTSILLITHDLALVREVADRVVVMYGGRIVE 235
Cdd:COG1126 144 RVAIARALAMEPKVMLFDEPTSALDpelvgeVL---DVMRDLA----KEGMTMVVVTHEMGFAREVADRVVFMDGGRIVE 216
|
250 260
....*....|....*....|...
gi 446453403 236 KGTIQEVIGSPKHPYTKSLLQAI 258
Cdd:COG1126 217 EGPPEEFFENPQHERTRAFLSKV 239
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
4-247 |
8.95e-45 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 153.12 E-value: 8.95e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESE 83
Cdd:cd03258 1 MIELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPT----SGSVLVDGTDLTLLSGKE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRgKDISFIFQ--DPLSSlnptmkvgRQITEVI---LQHEKKSKKEAKEIAINLLNDLGIheAEKRfEQYPHQLSGG 158
Cdd:cd03258 77 LRKAR-RRIGMIFQhfNLLSS--------RTVFENValpLEIAGVPKAEIEERVLELLELVGL--EDKA-DAYPAQLSGG 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 159 MRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGT 238
Cdd:cd03258 145 QKQRVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGT 224
|
....*....
gi 446453403 239 IQEVIGSPK 247
Cdd:cd03258 225 VEEVFANPQ 233
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
5-239 |
1.78e-44 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 151.86 E-value: 1.78e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSII-GLNQEsiqfDDGNISFESKDLTNlqese 83
Cdd:cd03293 1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKS-TLLRIIaGLERP----TSGEVLVDGEPVTG----- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnqiRGKDISFIFQDPlsSLNPTMKVGRQItEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMRQRI 163
Cdd:cd03293 71 ----PGPDRGYVFQQD--ALLPWLTVLDNV-ALGLELQGVPKAEARERAEELLELVGLSGFENA---YPHQLSGGMRQRV 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYG--GRIVEKGTI 239
Cdd:cd03293 141 ALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSArpGRIVAEVEV 218
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
4-235 |
2.49e-44 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 152.55 E-value: 2.49e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSII-GLnqesIQFDDGNISFESKDLTNLqes 82
Cdd:COG1116 7 ALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKS-TLLRLIaGL----EKPTSGEVLVDGKPVTGP--- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 ewnqirGKDISFIFQDPlsSLNPTMKVGRQItEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMRQR 162
Cdd:COG1116 79 ------GPDRGVVFQEP--ALLPWLTVLDNV-ALGLELRGVPKAERRERARELLELVGLAGFEDA---YPHQLSGGMRQR 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDV----TIQKQIMGLLKERKekqnTSILLITHDlalVRE---VADRVVVMYG--GRI 233
Cdd:COG1116 147 VAIARALANDPEVLLMDEPFGALDAltreRLQDELLRLWQETG----KTVLFVTHD---VDEavfLADRVVVLSArpGRI 219
|
..
gi 446453403 234 VE 235
Cdd:COG1116 220 VE 221
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
27-258 |
6.69e-44 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 151.52 E-value: 6.69e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKD-----LTNLQESEWNQIRGKDISFIFQDPLS 101
Cdd:TIGR02323 22 VSFDLYPGEVLGIVGESGSGKSTLLGCLAG----RLAPDHGTATYIMRSgaeleLYQLSEAERRRLMRTEWGFVHQNPRD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 SLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAekRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEP 181
Cdd:TIGR02323 98 GLRMRVSAGANIGERLMAIGARHYGNIRATAQDWLEEVEIDPT--RIDDLPRAFSGGMQQRLQIARNLVTRPRLVFMDEP 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 182 TTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLLQAI 258
Cdd:TIGR02323 176 TGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGLTDQVLDDPQHPYTQLLVSSI 252
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
27-257 |
8.04e-42 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 145.84 E-value: 8.04e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESK-----DLTNLQESEWNQIRGKDISFIFQDPLS 101
Cdd:PRK11701 25 VSFDLYPGEVLGIVGESGSGKTTLLNALSA----RLAPDAGEVHYRMRdgqlrDLYALSEAERRRLLRTEWGFVHQHPRD 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 SLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIheAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEP 181
Cdd:PRK11701 101 GLRMQVSAGGNIGERLMAVGARHYGDIRATAGDWLERVEI--DAARIDDLPTTFSGGMQQRLQIARNLVTHPRLVFMDEP 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 182 TTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTK----SLLQA 257
Cdd:PRK11701 179 TGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLTDQVLDDPQHPYTQllvsSVLQV 258
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
22-255 |
8.30e-42 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 146.47 E-value: 8.30e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESewnqIRGKDISFIFQDPLS 101
Cdd:PRK15112 27 EAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGM----IEPTSGELLIDDHPLHFGDYS----YRSQRIRMIFQDPST 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 SLNPTMKVGrQITEVILQhekkskkeakeiainLLNDLGIHEAEKRFEQ--------------YPHQLSGGMRQRICLAI 167
Cdd:PRK15112 99 SLNPRQRIS-QILDFPLR---------------LNTDLEPEQREKQIIEtlrqvgllpdhasyYPHMLAPGQKQRLGLAR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 168 AFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPK 247
Cdd:PRK15112 163 ALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASPL 242
|
....*...
gi 446453403 248 HPYTKSLL 255
Cdd:PRK15112 243 HELTKRLI 250
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
24-247 |
2.23e-41 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 144.02 E-value: 2.23e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEwnqirgKDISFIFQDplSSL 103
Cdd:cd03299 15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGF----IKPDSGKILLNGKDITNLPPEK------RDISYVPQN--YAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQItEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMRQRICLAIAFACHPKLVIADEPTT 183
Cdd:cd03299 83 FPHMTVYKNI-AYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNR---KPETLSGGEQQRVAIARALVVNPKILLLDEPFS 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 184 ALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPK 247
Cdd:cd03299 159 ALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPK 222
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
5-233 |
5.04e-41 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 141.38 E-value: 5.04e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTnlqeSEW 84
Cdd:cd03230 1 IEVRNLS----KRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGL----LKPDSGEIKVLGKDIK----KEP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRGKdISFIFQDPlsSLNPTMKVgRQitevilqhekkskkeakeiaiNLlndlgiheaekrfeqyphQLSGGMRQRIC 164
Cdd:cd03230 69 EEVKRR-IGYLPEEP--SLYENLTV-RE---------------------NL------------------KLSGGMKQRLA 105
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRI 233
Cdd:cd03230 106 LAQALLHDPELLILDEPTSGLDPESRREFWELLRELK-KEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
14-259 |
2.11e-40 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 142.78 E-value: 2.11e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 14 VEKENSKQEI---------VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:cd03294 21 LAKGKSKEEIlkktgqtvgVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRL----IEPTSGKVLIDGQDIAAMSRKEL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRGKDISFIFQDplSSLNPTMKVGRQIT---EVilQHEKKSKKEAKeiAINLLNDLGIHEAEkrfEQYPHQLSGGMRQ 161
Cdd:cd03294 97 RELRRKKISMVFQS--FALLPHRTVLENVAfglEV--QGVPRAEREER--AAEALELVGLEGWE---HKYPDELSGGMQQ 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 162 RICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQE 241
Cdd:cd03294 168 RVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEE 247
|
250
....*....|....*...
gi 446453403 242 VIGSPKHPYTKSLLQAIP 259
Cdd:cd03294 248 ILTNPANDYVREFFRGVD 265
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
7-268 |
2.35e-40 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 144.56 E-value: 2.35e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 7 LENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIqfddGNISFESKDLTNLQESEWNQ 86
Cdd:PRK11153 4 LKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTS----GRVLVDGQDLTALSEKELRK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 87 IRgKDISFIFQ--DPLSSLN--------------PTMKVGRQITEvilqhekkskkeakeiainLLNDLGIheAEKRfEQ 150
Cdd:PRK11153 80 AR-RQIGMIFQhfNLLSSRTvfdnvalplelagtPKAEIKARVTE-------------------LLELVGL--SDKA-DR 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 151 YPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYG 230
Cdd:PRK11153 137 YPAQLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDA 216
|
250 260 270
....*....|....*....|....*....|....*...
gi 446453403 231 GRIVEKGTIQEVIGSPKHPYTKSLLQAIPNMDDAEKVL 268
Cdd:PRK11153 217 GRLVEQGTVSEVFSHPKHPLTREFIQSTLHLDLPEDYL 254
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
4-235 |
3.86e-40 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 140.65 E-value: 3.86e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSII-GLNQESiqfdDGNISFESKDLTNLQES 82
Cdd:COG4181 8 IIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKS-TLLGLLaGLDRPT----SGTVRLAGQDLFALDED 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNQIRGKDISFIFQDplSSLNPTMkvgrqiT--E-VILQHEKKSKKEAKEIAINLLNDLGIheaEKRFEQYPHQLSGGM 159
Cdd:COG4181 83 ARARLRARHVGFVFQS--FQLLPTL------TalEnVMLPLELAGRRDARARARALLERVGL---GHRLDHYPAQLSGGE 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 160 RQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREvADRVVVMYGGRIVE 235
Cdd:COG4181 152 QQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRAGRLVE 226
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
5-242 |
6.97e-40 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 140.40 E-value: 6.97e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaVEKENSKQeIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:cd03256 1 IEVENLS--KTYPNGKK-ALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGL----VEPTSGSVLIDGTDINKLKGKAL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRgKDISFIFQDP------------LSSLNPTMKVGRqiteVILQhekKSKKEAKEIAINLLNDLGIHE-AEKRFEqy 151
Cdd:cd03256 74 RQLR-RQIGMIFQQFnlierlsvlenvLSGRLGRRSTWR----SLFG---LFPKEEKQRALAALERVGLLDkAYQRAD-- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 152 phQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGG 231
Cdd:cd03256 144 --QLSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDG 221
|
250
....*....|.
gi 446453403 232 RIVEKGTIQEV 242
Cdd:cd03256 222 RIVFDGPPAEL 232
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
4-250 |
7.46e-40 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 143.31 E-value: 7.46e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIqfDDGNISFESKDLTNLQESE 83
Cdd:COG3842 5 ALELENVS----KRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGF--ETP--DSGRILLDGRDVTGLPPEK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnqiRgkDISFIFQDPlsSLNPTMKVGrqitEVI---LQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMR 160
Cdd:COG3842 77 ----R--NVGMVFQDY--ALFPHLTVA----ENVafgLRMRGVPKAEIRARVAELLELVGLEGLADR---YPHQLSGGQQ 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDL--ALVreVADRVVVMYGGRIVEKGT 238
Cdd:COG3842 142 QRVALARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQeeALA--LADRIAVMNDGRIEQVGT 219
|
250
....*....|..
gi 446453403 239 IQEVIGSPKHPY 250
Cdd:COG3842 220 PEEIYERPATRF 231
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
4-243 |
8.58e-40 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 140.56 E-value: 8.58e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESE 83
Cdd:COG1120 1 MLEAENLSVGY----GGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGL----LKPSSGEVLLDGRDLASLSRRE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnqiRGKDISFIFQDPLSSLNptMKVgrqiTEVILQ----HEKKSKKEA---KEIAINLLNDLGIHE-AEKRFeqypHQL 155
Cdd:COG1120 73 ----LARRIAYVPQEPPAPFG--LTV----RELVALgrypHLGLFGRPSaedREAVEEALERTGLEHlADRPV----DEL 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 156 SGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVE 235
Cdd:COG1120 139 SGGERQRVLIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVA 218
|
....*...
gi 446453403 236 KGTIQEVI 243
Cdd:COG1120 219 QGPPEEVL 226
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
24-255 |
8.59e-40 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 140.17 E-value: 8.59e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQesewnqIRGKDISFIFQDplSSL 103
Cdd:cd03296 18 LDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERP----DSGTILFGGEDATDVP------VQERNVGFVFQH--YAL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTT 183
Cdd:cd03296 86 FRHMTVFDNVAFGLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFG 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446453403 184 ALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLL 255
Cdd:cd03296 166 ALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFL 237
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
24-255 |
1.29e-39 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 142.59 E-value: 1.29e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDL-TNL--QEsewnqiRGkdISFIFQDPL 100
Cdd:COG1118 18 LDDVSLEIASGELVALLGPSGSGKTTLLRIIAGL----ETPDSGRIVLNGRDLfTNLppRE------RR--VGFVFQHYA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 ssLNPTMKVG--------------RQITEVILQhekkskkeakeiainLLNDLGIHEAEKRfeqYPHQLSGGMRQRICLA 166
Cdd:COG1118 86 --LFPHMTVAeniafglrvrppskAEIRARVEE---------------LLELVQLEGLADR---YPSQLSGGQRQRVALA 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 167 IAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSP 246
Cdd:COG1118 146 RALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRP 225
|
....*....
gi 446453403 247 KHPYTKSLL 255
Cdd:COG1118 226 ATPFVARFL 234
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
5-237 |
2.04e-39 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 138.42 E-value: 2.04e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEw 84
Cdd:cd03259 1 LELKGLSKTYGS----VRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGL----ERPDSGEILIDGRDVTGVPPER- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqirgKDISFIFQDPlsSLNPTMKVGRQITEViLQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMRQRIC 164
Cdd:cd03259 72 -----RNIGMVFQDY--ALFPHLTVAENIAFG-LKLRGVPKAEIRARVRELLELVGLEGLLNR---YPHELSGGQQQRVA 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03259 141 LARALAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| LolD_lipo_ex |
TIGR02211 |
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ... |
4-235 |
6.67e-39 |
|
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 137.48 E-value: 6.67e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlAVEKENSKQ-EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQES 82
Cdd:TIGR02211 1 LLKCENLG-KRYQEGKLDtRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPT----SGEVLFNGQSLSKLSSN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNQIRGKDISFIFQ--------DPLSSLNPTMKVGRQ-ITEvilqhekkskkeAKEIAINLLNDLGIheaEKRFEQYPH 153
Cdd:TIGR02211 76 ERAKLRNKKLGFIYQfhhllpdfTALENVAMPLLIGKKsVKE------------AKERAYEMLEKVGL---EHRINHRPS 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREvADRVVVMYGGRI 233
Cdd:TIGR02211 141 ELSGGERQRVAIARALVNQPSLVLADEPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTHDLELAKK-LDRVLEMKDGQL 219
|
..
gi 446453403 234 VE 235
Cdd:TIGR02211 220 FN 221
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
14-233 |
8.13e-39 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 136.89 E-value: 8.13e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 14 VEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIQFddGNISFESKDLTNlQESEWNQIRgKDIS 93
Cdd:cd03262 6 LHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLL--EEPDS--GTIIIDGLKLTD-DKKNINELR-QKVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 94 FIFQDplSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEaekRFEQYPHQLSGGMRQRICLAIAFACHP 173
Cdd:cd03262 80 MVFQQ--FNLFPHLTVLENITLAPIKVKGMSKAEAEERALELLEKVGLAD---KADAYPAQLSGGQQQRVAIARALAMNP 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 174 KLVIADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYGGRI 233
Cdd:cd03262 155 KVMLFDEPTSALDPELVGEVLDVMKDLAEEGMT-MVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| 3a0106s01 |
TIGR00968 |
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions] |
14-258 |
1.07e-38 |
|
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
Pssm-ID: 130041 [Multi-domain] Cd Length: 237 Bit Score: 137.24 E-value: 1.07e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 14 VEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQesewnqIRGKDIS 93
Cdd:TIGR00968 6 ISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQP----DSGRIRLNGQDATRVH------ARDRKIG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 94 FIFQDplSSLNPTMKVGRQIT--EVILQHEKKSKKEAKEiaiNLLNDLGIheaEKRFEQYPHQLSGGMRQRICLAIAFAC 171
Cdd:TIGR00968 76 FVFQH--YALFKHLTVRDNIAfgLEIRKHPKAKIKARVE---ELLELVQL---EGLGDRYPNQLSGGQRQRVALARALAV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 172 HPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYT 251
Cdd:TIGR00968 148 EPQVLLLDEPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFV 227
|
....*..
gi 446453403 252 KSLLQAI 258
Cdd:TIGR00968 228 MSFLGEV 234
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
13-232 |
4.01e-37 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 131.16 E-value: 4.01e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 13 AVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIqfDDGNISFESKDLTnlQESEWNQIRGKDI 92
Cdd:cd03229 5 NVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGL--EEP--DSGSILIDGEDLT--DLEDELPPLRRRI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 93 SFIFQDPlsSLNPTMKVGRQITEVilqhekkskkeakeiainllndlgiheaekrfeqyphqLSGGMRQRICLAIAFACH 172
Cdd:cd03229 79 GMVFQDF--ALFPHLTVLENIALG--------------------------------------LSGGQQQRVALARALAMD 118
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 173 PKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGR 232
Cdd:cd03229 119 PDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
5-257 |
5.07e-37 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 132.81 E-value: 5.07e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlavEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEw 84
Cdd:cd03295 1 IEFENVT---KRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRL----IEPTSGEIFIDGEDIREQDPVE- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqIRGKdISFIFQDplSSLNPTMKVGRQITEViLQHEKKSKKEAKEIAINLLNDLGIHEAEKRfEQYPHQLSGGMRQRIC 164
Cdd:cd03295 73 --LRRK-IGYVIQQ--IGLFPHMTVEENIALV-PKLLKWPKEKIRERADELLALVGLDPAEFA-DRYPHELSGGQQQRVG 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIG 244
Cdd:cd03295 146 VARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILR 225
|
250
....*....|...
gi 446453403 245 SPKHPYTKSLLQA 257
Cdd:cd03295 226 SPANDFVAEFVGA 238
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
6-237 |
2.37e-36 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 129.09 E-value: 2.37e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 6 SLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEWN 85
Cdd:cd03214 1 EVENLSVGY----GGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGL----LKPSSGEILLDGKDLASLSPKELA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 86 QIRGkdisfifqdplsslnptmkvgrqiteVILQhekkskkeakeiainLLNDLGI-HEAEKRFeqypHQLSGGMRQRIC 164
Cdd:cd03214 73 RKIA--------------------------YVPQ---------------ALELLGLaHLADRPF----NELSGGERQRVL 107
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03214 108 LARALAQEPPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-243 |
3.40e-36 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 130.98 E-value: 3.40e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNlq 80
Cdd:COG1121 3 MMPAIELENLTVSYGG----RPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGL----LPPTSGTVRLFGKPPRR-- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 esewnqiRGKDISFIFQdpLSSLNPTMkvgrQIT--EVILQHEKKSK-------KEAKEIAINLLNDLGIHE-AEKRFeq 150
Cdd:COG1121 73 -------ARRRIGYVPQ--RAEVDWDF----PITvrDVVLMGRYGRRglfrrpsRADREAVDEALERVGLEDlADRPI-- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 151 ypHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYG 230
Cdd:COG1121 138 --GELSGGQQQRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELR-REGKTILVVTHDLGAVREYFDRVLLLNR 214
|
250
....*....|...
gi 446453403 231 GRIVEkGTIQEVI 243
Cdd:COG1121 215 GLVAH-GPPEEVL 226
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
24-183 |
4.62e-36 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 127.38 E-value: 4.62e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQEsewnQIRGKDISFIFQDPlsSL 103
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGL----LSPTEGTILLDGQDLTDDER----KSLRKEIGYVFQDP--QL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITEViLQHEKKSKKEAKEIAINLLNDLGIHEAEKRF-EQYPHQLSGGMRQRICLAIAFACHPKLVIADEPT 182
Cdd:pfam00005 71 FPRLTVRENLRLG-LLLKGLSKREKDARAEEALEKLGLGDLADRPvGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
|
.
gi 446453403 183 T 183
Cdd:pfam00005 150 A 150
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
5-233 |
4.69e-36 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 129.55 E-value: 4.69e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:COG4619 1 LELEGLSFRV----GGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADL----DPPTSGEIYLDGKPLSAMPPPEW 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqiRgKDISFIFQDPLssLnPTMKVGRQITEVilqHEKKSKKEAKEIAINLLNDLGIHEA--EKRFEQyphqLSGGMRQR 162
Cdd:COG4619 73 ---R-RQVAYVPQEPA--L-WGGTVRDNLPFP---FQLRERKFDRERALELLERLGLPPDilDKPVER----LSGGERQR 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRI 233
Cdd:COG4619 139 LALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
5-243 |
1.53e-35 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 136.50 E-value: 1.53e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQESEW 84
Cdd:COG2274 474 IELENVSFRYPGDS--PPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEP----TSGRILIDGIDLRQIDPASL 547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIrgkdISFIFQDP------------LSSLNPTMKvgrQITEVilqhekkskkeakeiainlLNDLGIHE-AEKRFEQY 151
Cdd:COG2274 548 RRQ----IGVVLQDVflfsgtirenitLGDPDATDE---EIIEA-------------------ARLAGLHDfIEALPMGY 601
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 152 PHQ-------LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERkeKQNTSILLITHDLALVREvADR 224
Cdd:COG2274 602 DTVvgeggsnLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRL--LKGRTVIIIAHRLSTIRL-ADR 678
|
250
....*....|....*....
gi 446453403 225 VVVMYGGRIVEKGTIQEVI 243
Cdd:COG2274 679 IIVLDKGRIVEDGTHEELL 697
|
|
| heterocyst_DevA |
TIGR02982 |
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ... |
20-234 |
3.52e-35 |
|
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.
Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 127.44 E-value: 3.52e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 20 KQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSIIGlNQESIQfdDGNISFESKDLTNLQESEWNQIRgKDISFIFQ-- 97
Cdd:TIGR02982 17 RKQVLFDINLEINPGEIVILTGPSGSGKT-TLLTLIG-GLRSVQ--EGSLKVLGQELHGASKKQLVQLR-RRIGYIFQah 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 DPLSSLNPTMKVgrQITEVILQHEKKSKKEAKEIAInlLNDLGIheaEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVI 177
Cdd:TIGR02982 92 NLLGFLTARQNV--QMALELQPNLSYQEARERARAM--LEAVGL---GDHLNYYPHNLSGGQKQRVAIARALVHHPKLVL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 178 ADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVrEVADRVVVMYGGRIV 234
Cdd:TIGR02982 165 ADEPTAALDSKSGRDVVELMQKLAKEQGCTILMVTHDNRIL-DVADRILQMEDGKLL 220
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
4-242 |
5.20e-35 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 127.67 E-value: 5.20e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTnlqeSE 83
Cdd:COG4555 1 MIEVENLS----KKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGL----LKPDSGSILIDGEDVR----KE 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRgKDISFIFQDPlsSLNPTMKVGRQITEVILQHEKKSKKEAKEIAiNLLNDLGIHEAEKRfeqYPHQLSGGMRQRI 163
Cdd:COG4555 69 PREAR-RQIGVLPDER--GLYDRLTVRENIRYFAELYGLFDEELKKRIE-ELIELLGLEEFLDR---RVGELSTGMKKKV 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:COG4555 142 ALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALK-KEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDEL 219
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
5-235 |
6.39e-35 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 126.71 E-value: 6.39e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKensKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:COG2884 2 IRFENVSKRYPG---GREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGE----ERPTSGQVLVNGQDLSRLKRREI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRgKDISFIFQDP--LSSLN-------PtMKVGRQITEVILQHekkskkeakeiAINLLNDLGIHEAEKRfeqYPHQL 155
Cdd:COG2884 75 PYLR-RRIGVVFQDFrlLPDRTvyenvalP-LRVTGKSRKEIRRR-----------VREVLDLVGLSDKAKA---LPHEL 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 156 SGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRIVE 235
Cdd:COG2884 139 SGGEQQRVAIARALVNRPELLLADEPTGNLDPETSWEIMELLEEIN-RRGTTVLIATHDLELVDRMPKRVLELEDGRLVR 217
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
5-232 |
6.76e-35 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 125.19 E-value: 6.76e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEkeNSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQESEW 84
Cdd:cd03228 1 IEFKNVSFSYP--GRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDP----TSGEILIDGVDLRDLDLESL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIrgkdISFIFQDPlsslnptmkvgrqitevILQHEKkskkeakeIAINLLndlgiheaekrfeqyphqlSGGMRQRIC 164
Cdd:cd03228 75 RKN----IAYVPQDP-----------------FLFSGT--------IRENIL-------------------SGGQRQRIA 106
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDLALVREvADRVVVMYGGR 232
Cdd:cd03228 107 IARALLRDPPILILDEATSALDPETEALILEAL--RALAKGKTVIVIAHRLSTIRD-ADRIIVLDDGR 171
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-242 |
1.06e-34 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 127.82 E-value: 1.06e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLavEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTnlQ 80
Cdd:PRK13635 2 KEEIIRVEHISF--RYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGL----LLPEAGTITVGGMVLS--E 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 ESEWnQIRgKDISFIFQDPLSSLnptmkVGRQITEvilqhekkskkeakEIAINLLNDlGI---------HEAEKR---- 147
Cdd:PRK13635 74 ETVW-DVR-RQVGMVFQNPDNQF-----VGATVQD--------------DVAFGLENI-GVpreemvervDQALRQvgme 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 148 --FEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREvADRV 225
Cdd:PRK13635 132 dfLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRV 210
|
250
....*....|....*..
gi 446453403 226 VVMYGGRIVEKGTIQEV 242
Cdd:PRK13635 211 IVMNKGEILEEGTPEEI 227
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
5-241 |
2.18e-34 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 132.19 E-value: 2.18e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKEnskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:COG4988 337 IELEDVSFSYPGG---RPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGF----LPPYSGSILINGVDLSDLDPASW 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQirgkDISFIFQDP------------LSSLNPTMKvgrQITEVilqhekkskkeakeiainlLNDLGIHEaekrF-EQY 151
Cdd:COG4988 410 RR----QIAWVPQNPylfagtirenlrLGRPDASDE---ELEAA-------------------LEAAGLDE----FvAAL 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 152 PH-----------QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERkeKQNTSILLITHDLALVRE 220
Cdd:COG4988 460 PDgldtplgeggrGLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRL--AKGRTVILITHRLALLAQ 537
|
250 260
....*....|....*....|.
gi 446453403 221 vADRVVVMYGGRIVEKGTIQE 241
Cdd:COG4988 538 -ADRILVLDDGRIVEQGTHEE 557
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
6-232 |
7.79e-34 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 121.97 E-value: 7.79e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 6 SLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEWn 85
Cdd:cd00267 1 EIENLSFRYGG----RTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGL----LKPTSGEILIDGKDIAKLPLEEL- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 86 qirGKDISFIFQdplsslnptmkvgrqitevilqhekkskkeakeiainllndlgiheaekrfeqyphqLSGGMRQRICL 165
Cdd:cd00267 72 ---RRRIGYVPQ---------------------------------------------------------LSGGQRQRVAL 91
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 166 AIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYGGR 232
Cdd:cd00267 92 ARALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEEGRT-VIIVTHDPELAELAADRVIVLKDGK 157
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
16-256 |
3.54e-33 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 122.94 E-value: 3.54e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 16 KENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQ-ESIQFDDGNISFESKDLTNLQESEWNQIRgKDISF 94
Cdd:PRK11264 11 KKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQpEAGTIRVGDITIDTARSLSQQKGLIRQLR-QHVGF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 95 IFQDplSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEkrfEQYPHQLSGGMRQRICLAIAFACHPK 174
Cdd:PRK11264 90 VFQN--FNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKE---TSYPRRLSGGQQQRVAIARALAMRPE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 175 LVIADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSL 254
Cdd:PRK11264 165 VILFDEPTSALDPELVGEVLNTIRQLAQEKRT-MVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQPRTRQF 243
|
..
gi 446453403 255 LQ 256
Cdd:PRK11264 244 LE 245
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
6-234 |
1.39e-32 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 120.05 E-value: 1.39e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 6 SLENVTlavEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQesewn 85
Cdd:cd03226 1 RIENIS---FSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKES----SGSILLNGKPIKAKE----- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 86 qiRGKDISFIFQDPlsslnptmkvGRQIT------EVILqhEKKSKKEAKEIAINLLNDLGIHEAEkrfEQYPHQLSGGM 159
Cdd:cd03226 69 --RRKSIGYVMQDV----------DYQLFtdsvreELLL--GLKELDAGNEQAETVLKDLDLYALK---ERHPLSLSGGQ 131
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 160 RQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRIV 234
Cdd:cd03226 132 KQRLAIAAALLSGKDLLIFDEPTSGLDYKNMERVGELIRELA-AQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-247 |
1.56e-32 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 123.64 E-value: 1.56e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLlSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIqfDDGNISFESKDLTNLQ 80
Cdd:COG3839 1 MASL-ELENVS----KSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGL--EDP--TSGEILIGGRDVTDLP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 ESEwnqiRgkDISFIFQDPlsSLNPTMKVG------------------RQITEVilqhekkskkeakeiainlLNDLGIH 142
Cdd:COG3839 72 PKD----R--NIAMVFQSY--ALYPHMTVYeniafplklrkvpkaeidRRVREA-------------------AELLGLE 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 143 EAEKRfeqYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHD----LALv 218
Cdd:COG3839 125 DLLDR---KPKQLSGGQRQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDqveaMTL- 200
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 446453403 219 revADRVVVMYGGRIVEKGTIQEV------------IGSPK 247
Cdd:COG3839 201 ---ADRIAVMNDGRIQQVGTPEELydrpanlfvagfIGSPP 238
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
5-237 |
9.72e-32 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 118.13 E-value: 9.72e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIqfDDGNISFESKDLTNLQESEw 84
Cdd:cd03301 1 VELENVT----KRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGL--EEP--TSGRIYIGGRDVTDLPPKD- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqirgKDISFIFQDplSSLNPTMKVgrqitevilqhekkskkeAKEIAINL-LNDLGIHEAEKRFEQ------------- 150
Cdd:cd03301 72 -----RDIAMVFQN--YALYPHMTV------------------YDNIAFGLkLRKVPKDEIDERVREvaellqiehlldr 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 151 YPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYG 230
Cdd:cd03301 127 KPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMND 206
|
....*..
gi 446453403 231 GRIVEKG 237
Cdd:cd03301 207 GQIQQIG 213
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
5-256 |
1.25e-31 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 124.49 E-value: 1.25e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEkeNSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:COG4987 334 LELEDVSFRYP--GAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRF----LDPQSGSITLGGVDLRDLDEDDL 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIrgkdISFIFQDP---LSSLNPTMKVGR------QITEVilqhekkskkeakeiainlLNDLGIHEAekrFEQYPH-- 153
Cdd:COG4987 408 RRR----IAVVPQRPhlfDTTLRENLRLARpdatdeELWAA-------------------LERVGLGDW---LAALPDgl 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 ---------QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKER-KEKqntSILLITHDLALVrEVAD 223
Cdd:COG4987 462 dtwlgeggrRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEAlAGR---TVLLITHRLAGL-ERMD 537
|
250 260 270
....*....|....*....|....*....|...
gi 446453403 224 RVVVMYGGRIVEKGTIQEVIGspKHPYTKSLLQ 256
Cdd:COG4987 538 RILVLEDGRIVEQGTHEELLA--QNGRYRQLYQ 568
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
5-242 |
2.49e-31 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 117.67 E-value: 2.49e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKEnskqEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQF-DDGNISFESKDLTNLQESE 83
Cdd:cd03260 1 IELRDLNVYYGDK----HALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGApDEGEVLLDGKDIYDLDVDV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wNQIRgKDISFIFQDPlsslNP-TMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfEQYPHQLSGGMRQR 162
Cdd:cd03260 77 -LELR-RRVGMVFQKP----NPfPGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKD-RLHALGLSGGQQQR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERkeKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:cd03260 150 LCLARALANEPEVLLLDEPTSALDPISTAKIEELIAEL--KKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
1-250 |
5.02e-31 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 119.76 E-value: 5.02e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVtlavEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQ 80
Cdd:TIGR03265 1 SSPYLSIDNI----RKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQ----TAGTIYQGGRDITRLP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 ESEwnqirgKDISFIFQDplSSLNPTMKVGRQItEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMR 160
Cdd:TIGR03265 73 PQK------RDYGIVFQS--YALFPNLTVADNI-AYGLKNRGMGRAEVAERVAELLDLVGLPGSERK---YPGQLSGGQQ 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDL--ALVreVADRVVVMYGGRIVEKGT 238
Cdd:TIGR03265 141 QRVALARALATSPGLLLLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQeeALS--MADRIVVMNHGVIEQVGT 218
|
250
....*....|..
gi 446453403 239 IQEVIGSPKHPY 250
Cdd:TIGR03265 219 PQEIYRHPATPF 230
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
23-241 |
5.71e-31 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 116.45 E-value: 5.71e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIqfddGNISFESKDLTnlqeSEWNQIRgKDISFIFQDplSS 102
Cdd:cd03263 17 AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTS----GTAYINGYSIR----TDRKAAR-QSLGYCPQF--DA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 103 LNPTMKVgRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFeqyPHQLSGGMRQRICLAIAFACHPKLVIADEPT 182
Cdd:cd03263 86 LFDELTV-REHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKR---ARTLSGGMKRKLSLAIALIGGPSVLLLDEPT 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 183 TALDVTIQKQIMGLLKerKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQE 241
Cdd:cd03263 162 SGLDPASRRAIWDLIL--EVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQE 218
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
5-247 |
2.43e-30 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 115.03 E-value: 2.43e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQESEw 84
Cdd:cd03300 1 IELENVS----KFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETP----TSGEILLDGKDITNLPPHK- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqirgKDISFIFQDplSSLNPTMKVGRQITeVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMRQRIC 164
Cdd:cd03300 72 -----RPVNTVFQN--YALFPHLTVFENIA-FGLRLKKLPKAEIKERVAEALDLVQLEGYANR---KPSQLSGGQQQRVA 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIG 244
Cdd:cd03300 141 IARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYE 220
|
...
gi 446453403 245 SPK 247
Cdd:cd03300 221 EPA 223
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
24-247 |
2.44e-30 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 115.23 E-value: 2.44e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQEsewNQIRGKDISFIFQDPlsSL 103
Cdd:cd03219 16 LDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGF----LRPTSGSVLFDGEDITGLPP---HEIARLGIGRTFQIP--RL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKV---------GRQITEVILQHEKKSKKEAKEIAINLLNDLGIheAEKRFEQyPHQLSGGMRQRICLAIAFACHPK 174
Cdd:cd03219 87 FPELTVlenvmvaaqARTGSGLLLARARREEREARERAEELLERVGL--ADLADRP-AGELSYGQQRRLEIARALATDPK 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 175 LVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPK 247
Cdd:cd03219 164 LLLLDEPAAGLNPEETEELAELIRELRE-RGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPR 235
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
14-246 |
3.87e-30 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 117.49 E-value: 3.87e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 14 VEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQEsewnqiRGKDIS 93
Cdd:PRK10851 8 IKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQT----SGHIRFHGTDVSRLHA------RDRKVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 94 FIFQDplSSLNPTMKVGRQIT---EVILQHEKKSKKEAKEIAINLLNDLGI-HEAEKrfeqYPHQLSGGMRQRICLAIAF 169
Cdd:PRK10851 78 FVFQH--YALFRHMTVFDNIAfglTVLPRRERPNAAAIKAKVTQLLEMVQLaHLADR----YPAQLSGGQKQRVALARAL 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 170 ACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSP 246
Cdd:PRK10851 152 AVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREP 228
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
6-228 |
5.15e-30 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 113.78 E-value: 5.15e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 6 SLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNlqesEWN 85
Cdd:cd03235 1 EVEDLTVSY----GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGL----LKPTSGSIRVFGKPLEK----ERK 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 86 ------QIRGKDISF---IFQDPLSSLNPTMKVGRQITEvilqhekkskkEAKEIAINLLNDLGIHE-AEKRFEqyphQL 155
Cdd:cd03235 69 rigyvpQRRSIDRDFpisVRDVVLMGLYGHKGLFRRLSK-----------ADKAKVDEALERVGLSElADRQIG----EL 133
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 156 SGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVM 228
Cdd:cd03235 134 SGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRREGMT-ILVVTHDLGLVLEYFDRVLLL 205
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
4-247 |
2.90e-29 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 112.82 E-value: 2.90e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlavekensKQ----EIVKHVSFSINEGEIVALVGESGSGKSvTAQSII-GLnqesIQFDDGNISFESKDLTN 78
Cdd:COG0411 4 LLEVRGLT--------KRfgglVAVDDVSLEVERGEIVGLIGPNGAGKT-TLFNLItGF----YRPTSGRILFDGRDITG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 79 LQEsewNQIRGKDISFIFQdpLSSLNPTMKV------------GRQITEVILQHEKKSKKEAKEI--AINLLNDLGIHEa 144
Cdd:COG0411 71 LPP---HRIARLGIARTFQ--NPRLFPELTVlenvlvaaharlGRGLLAALLRLPRARREEREARerAEELLERVGLAD- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 145 ekRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADR 224
Cdd:COG0411 145 --RADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADR 222
|
250 260
....*....|....*....|...
gi 446453403 225 VVVMYGGRIVEKGTIQEVIGSPK 247
Cdd:COG0411 223 IVVLDFGRVIAEGTPAEVRADPR 245
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
5-243 |
3.50e-29 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 117.57 E-value: 3.50e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKEnskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:COG1132 340 IEFENVSFSYPGD---RPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRF----YDPTSGRILIDGVDIRDLTLESL 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqiRGKdISFIFQDP------------LSSLNPTMKvgrQITEVilqhekkskkeakeiainlLNDLGIHEAEKRFEQ-Y 151
Cdd:COG1132 413 ---RRQ-IGVVPQDTflfsgtirenirYGRPDATDE---EVEEA-------------------AKAAQAHEFIEALPDgY 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 152 PHQ-------LSGGMRQRICLAIAFACHPKLVIADEPTTALDV----TIQKQIMGLLKERkekqnTSIlLITHDLALVRE 220
Cdd:COG1132 467 DTVvgergvnLSGGQRQRIAIARALLKDPPILILDEATSALDTeteaLIQEALERLMKGR-----TTI-VIAHRLSTIRN 540
|
250 260
....*....|....*....|...
gi 446453403 221 vADRVVVMYGGRIVEKGTIQEVI 243
Cdd:COG1132 541 -ADRILVLDDGRIVEQGTHEELL 562
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
22-247 |
3.60e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 113.34 E-value: 3.60e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGL---NQESIQFDDGNISFESKDltnlqeSEWNQIRgKDISFIFQD 98
Cdd:PRK13646 21 QAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALlkpTTGTVTVDDITITHKTKD------KYIRPVR-KRIGMVFQF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 PLSSLNPTmKVGRQItEVILQHEKKSKKEAKEIAINLLNDLGIheAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIA 178
Cdd:PRK13646 94 PESQLFED-TVEREI-IFGPKNFKMNLDEVKNYAHRLLMDLGF--SRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 179 DEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPK 247
Cdd:PRK13646 170 DEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKK 238
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
14-258 |
4.95e-29 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 115.52 E-value: 4.95e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 14 VEKENSKQEI---------VKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFESKDLTNLQESEW 84
Cdd:PRK10070 25 IEQGLSKEQIlektglslgVKDASLAIEEGEIFVIMGLSGSGKS----TMVRLLNRLIEPTRGQVLIDGVDIAKISDAEL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRGKDISFIFQDplSSLNPTMKVGRQiTEVILQHEKKSKKEAKEIAINLLNDLGIheaEKRFEQYPHQLSGGMRQRIC 164
Cdd:PRK10070 101 REVRRKKIAMVFQS--FALMPHMTVLDN-TAFGMELAGINAEERREKALDALRQVGL---ENYAHSYPDELSGGMRQRVG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIG 244
Cdd:PRK10070 175 LARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILN 254
|
250
....*....|....
gi 446453403 245 SPKHPYTKSLLQAI 258
Cdd:PRK10070 255 NPANDYVRTFFRGV 268
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
25-237 |
5.95e-29 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 110.85 E-value: 5.95e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 25 KHVSFSIN-----EGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFeskDLTNLQESEWNQI---RGKDISFIF 96
Cdd:cd03297 9 RLPDFTLKidfdlNEEVTGIFGASGAGKSTLLRCIAGL----EKPDGGTIVL---NGTVLFDSRKKINlppQQRKIGLVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 97 QDplSSLNPTMKVGRQITEVILQHEKKSKKEAKEiaiNLLNDLGIHEAEKRfeqYPHQLSGGMRQRICLAIAFACHPKLV 176
Cdd:cd03297 82 QQ--YALFPHLNVRENLAFGLKRKRNREDRISVD---ELLDLLGLDHLLNR---YPAQLSGGEKQRVALARALAAQPELL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446453403 177 IADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03297 154 LLDEPFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
4-239 |
6.89e-29 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 111.45 E-value: 6.89e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESE 83
Cdd:PRK11629 5 LLQCDNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPT----SGDVIFNGQPMSKLSSAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRGKDISFIFQdpLSSLNPTMKVGRQITEVILQHEKKSKKEAKEiAINLLNDLGIheaEKRFEQYPHQLSGGMRQRI 163
Cdd:PRK11629 81 KAELRNQKLGFIYQ--FHHLLPDFTALENVAMPLLIGKKKPAEINSR-ALEMLAAVGL---EHRANHRPSELSGGERQRV 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVaDRVVVMYGGRIVEKGTI 239
Cdd:PRK11629 155 AIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRM-SRQLEMRDGRLTAELSL 229
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
14-256 |
1.16e-28 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 110.95 E-value: 1.16e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 14 VEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIqfDDGNISFESKDLTNLQESEwNQIRgKDIS 93
Cdd:PRK09493 7 VSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKL--EEI--TSGDLIVDGLKVNDPKVDE-RLIR-QEAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 94 FIFQDplSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEaekRFEQYPHQLSGGMRQRICLAIAFACHP 173
Cdd:PRK09493 81 MVFQQ--FYLFPHLTALENVMFGPLRVRGASKEEAEKQARELLAKVGLAE---RAHHYPSELSGGQQQRVAIARALAVKP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 174 KLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSIlLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKS 253
Cdd:PRK09493 156 KLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMV-IVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQE 234
|
...
gi 446453403 254 LLQ 256
Cdd:PRK09493 235 FLQ 237
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
5-235 |
3.65e-28 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 109.95 E-value: 3.65e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNlqesew 84
Cdd:COG4525 4 LTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGF----LAPSSGEITLDGVPVTG------ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqiRGKDISFIFQDplSSLNPTMKVgRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFeqyPHQLSGGMRQRIC 164
Cdd:COG4525 74 ---PGADRGVVFQK--DALLPWLNV-LDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRR---IWQLSGGMRQRVG 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDL--ALVreVADRVVVMYG--GRIVE 235
Cdd:COG4525 145 IARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVeeALF--LATRLVVMSPgpGRIVE 217
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-242 |
4.15e-28 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 110.18 E-value: 4.15e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLAVEKENSKQEI--VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDlTN 78
Cdd:PRK13633 1 MNEMIKCKNVSYKYESNEESTEKlaLDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPS----EGKVYVDGLD-TS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 79 LQESEWNqIRGKdISFIFQDPlsslnptmkvGRQITEVILQHEkkskkeakeIAINLLNdLGI---------HEAEKRFE 149
Cdd:PRK13633 76 DEENLWD-IRNK-AGMVFQNP----------DNQIVATIVEED---------VAFGPEN-LGIppeeirervDESLKKVG 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 150 QY------PHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREvAD 223
Cdd:PRK13633 134 MYeyrrhaPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-AD 212
|
250
....*....|....*....
gi 446453403 224 RVVVMYGGRIVEKGTIQEV 242
Cdd:PRK13633 213 RIIVMDSGKVVMEGTPKEI 231
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
4-233 |
5.79e-28 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 107.13 E-value: 5.79e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEkenskqeiVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQesiqFDDGNISFESKDLTNLQESE 83
Cdd:cd03215 4 VLEVRGLSVKGA--------VRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRP----PASGEITLDGKPVTRRSPRD 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WnqiRGKDISFIFQDplsslnptmkvgRQITEVILQHEkkskkeakeIAINLLNdlgiheaekrfeqyPHQLSGGMRQRI 163
Cdd:cd03215 72 A---IRAGIAYVPED------------RKREGLVLDLS---------VAENIAL--------------SSLLSGGNQQKV 113
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRI 233
Cdd:cd03215 114 VLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELAD-AGKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1-256 |
9.42e-28 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 109.41 E-value: 9.42e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLAVEKENSKQEIvKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTnlQ 80
Cdd:PRK13642 1 MNKILEVENLVFKYEKESDVNQL-NGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEF----EGKVKIDGELLT--A 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 ESEWNQIRgkDISFIFQDPL-----SSLNPTMKVGRQiTEVILQHEKKSKKEAKEIAINLLnDLGIHEaekrfeqyPHQL 155
Cdd:PRK13642 74 ENVWNLRR--KIGMVFQNPDnqfvgATVEDDVAFGME-NQGIPREEMIKRVDEALLAVNML-DFKTRE--------PARL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 156 SGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREvADRVVVMYGGRIVE 235
Cdd:PRK13642 142 SGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIK 220
|
250 260
....*....|....*....|....*....
gi 446453403 236 KGTIQEVIGSPKH--------PYTKSLLQ 256
Cdd:PRK13642 221 EAAPSELFATSEDmveigldvPFSSNLMK 249
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
14-256 |
1.08e-27 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 108.90 E-value: 1.08e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 14 VEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQES---IQFDDGNISFESKDLTNLQESEWNQIR-- 88
Cdd:PRK10619 11 LHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSegsIVVNGQTINLVRDKDGQLKVADKNQLRll 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 89 GKDISFIFQDplSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKrfEQYPHQLSGGMRQRICLAIA 168
Cdd:PRK10619 91 RTRLTMVFQH--FNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQ--GKYPVHLSGGQQQRVSIARA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 169 FACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKH 248
Cdd:PRK10619 167 LAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKT-MVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQS 245
|
....*...
gi 446453403 249 PYTKSLLQ 256
Cdd:PRK10619 246 PRLQQFLK 253
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
24-242 |
3.31e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 108.21 E-value: 3.31e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNlQESEWNQIRgKDISFIFQDPlssl 103
Cdd:PRK13637 23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPT----SGKIIIDGVDITD-KKVKLSDIR-KKVGLVFQYP---- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 nptmkvgrqitevilQHEKKSKKEAKEIA---INL-LNDLGIHEAEKR--------FEQY----PHQLSGGMRQRICLAI 167
Cdd:PRK13637 93 ---------------EYQLFEETIEKDIAfgpINLgLSEEEIENRVKRamnivgldYEDYkdksPFELSGGQKRRVAIAG 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 168 AFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK13637 158 VVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREV 232
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-242 |
4.26e-27 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 107.89 E-value: 4.26e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTnlqESEW 84
Cdd:COG4152 2 LELKGLT----KRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGI----LAPDSGEVLWDGEPLD---PEDR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQI------RGkdisfifqdplssLNPTMKVGRQIT-----------EVILQhekkskkeakeiAINLLNDLGIHE-AEK 146
Cdd:COG4152 71 RRIgylpeeRG-------------LYPKMKVGEQLVylarlkglskaEAKRR------------ADEWLERLGLGDrANK 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 147 RFEQyphqLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKqNTSILLITHDLALVREVADRVV 226
Cdd:COG4152 126 KVEE----LSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAK-GTTVIFSSHQMELVEELCDRIV 200
|
250
....*....|....*.
gi 446453403 227 VMYGGRIVEKGTIQEV 242
Cdd:COG4152 201 IINKGRKVLSGSVDEI 216
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
4-241 |
4.94e-27 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 106.02 E-value: 4.94e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESE 83
Cdd:PRK10584 6 IVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGS----SGEVSLVGQPLHQMDEEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRGKDISFIFQDPLssLNPTMKVGRQITEVILQHEKKSKKEAKEiAINLLNDLGIheaEKRFEQYPHQLSGGMRQRI 163
Cdd:PRK10584 82 RAKLRAKHVGFVFQSFM--LIPTLNALENVELPALLRGESSRQSRNG-AKALLEQLGL---GKRLDHLPAQLSGGEQQRV 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVvvmyggRIVEkGTIQE 241
Cdd:PRK10584 156 ALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRRL------RLVN-GQLQE 226
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
5-234 |
5.80e-27 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 104.05 E-value: 5.80e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFEskdltnlqesew 84
Cdd:cd03216 1 LELRGIT----KRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGL----YKPDSGEILVD------------ 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqirGKDISFifqdplssLNPTMKvgrqitevilqhekkskkeakeiainllNDLGIheaekrfeQYPHQLSGGMRQRIC 164
Cdd:cd03216 61 ----GKEVSF--------ASPRDA----------------------------RRAGI--------AMVYQLSVGERQMVE 92
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRIV 234
Cdd:cd03216 93 IARALARNARLLILDEPTAALTPAEVERLFKVIRRLR-AQGVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
11-237 |
6.34e-27 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 105.38 E-value: 6.34e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 11 TLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLqESEWNQIrGK 90
Cdd:cd03268 3 TNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGL----IKPDSGEITFDGKSYQKN-IEALRRI-GA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 91 DISF-IFQDPLSslnptmkvGRqitEVILQHEKKSKKEAKEIAiNLLNDLGIHEAE-KRFEQYphqlSGGMRQRICLAIA 168
Cdd:cd03268 77 LIEApGFYPNLT--------AR---ENLRLLARLLGIRKKRID-EVLDVVGLKDSAkKKVKGF----SLGMKQRLGIALA 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 169 FACHPKLVIADEPTTALDVTIQKQIMGLLKeRKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03268 141 LLGNPDLLILDEPTNGLDPDGIKELRELIL-SLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-234 |
7.72e-27 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 110.97 E-value: 7.72e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSIIG-LNQESiqfdDGNISFESKDLTNL 79
Cdd:PRK10535 1 MTALLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKS-TLMNILGcLDKPT----SGTYRVAGQDVATL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 80 QESEWNQIRGKDISFIFQ--DPLSSLNPTMKVgrqitEVILQHEKKSKKEAKEIAINLLNDLGIHEaekRFEQYPHQLSG 157
Cdd:PRK10535 76 DADALAQLRREHFGFIFQryHLLSHLTAAQNV-----EVPAVYAGLERKQRLLRAQELLQRLGLED---RVEYQPSQLSG 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 158 GMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSIlLITHDlALVREVADRVVVMYGGRIV 234
Cdd:PRK10535 148 GQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVI-IVTHD-PQVAAQAERVIEIRDGEIV 222
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
27-246 |
9.35e-27 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 108.26 E-value: 9.35e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLtnlQESEwnqiRGKD-------ISFIFQDP 99
Cdd:COG4148 18 VDFTLPGRGVTALFGPSGSGKTTLLRAIAGL----ERPDSGRIRLGGEVL---QDSA----RGIFlpphrrrIGYVFQEA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 lsSLNPTMKV------GRQITEVILQHEKKSKkeakeiAINLLndlGIheaEKRFEQYPHQLSGGMRQRICLAIAFACHP 173
Cdd:COG4148 87 --RLFPHLSVrgnllyGRKRAPRAERRISFDE------VVELL---GI---GHLLDRRPATLSGGERQRVAIGRALLSSP 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 174 KLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSP 246
Cdd:COG4148 153 RLLLMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRP 225
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
5-255 |
1.50e-26 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 104.84 E-value: 1.50e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENskqeivKHVSFSINEGEIVALVGESGSGKSvTAQSII-GLNQEsiqfDDGNISFESKDLTNLQESE 83
Cdd:COG3840 2 LRLDDLTYRYGDFP------LRFDLTIAAGERVAILGPSGAGKS-TLLNLIaGFLPP----DSGRILWNGQDLTALPPAE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnqiRGkdISFIFQD----P-LS-------SLNPTMKVGR-QITEVIlqhekkskkeakeiaiNLLNDLGIHEAEKRfeq 150
Cdd:COG3840 71 ----RP--VSMLFQEnnlfPhLTvaqniglGLRPGLKLTAeQRAQVE----------------QALERVGLAGLLDR--- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 151 YPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYG 230
Cdd:COG3840 126 LPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVAD 205
|
250 260
....*....|....*....|....*
gi 446453403 231 GRIVEKGTIQEVIGSPKHPYTKSLL 255
Cdd:COG3840 206 GRIAADGPTAALLDGEPPPALAAYL 230
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
5-228 |
2.07e-26 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 104.10 E-value: 2.07e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDdGNISFESKDLTNLQesew 84
Cdd:COG4136 2 LSLENLTITLGG----RPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAFSAS-GEVLLNGRRLTALP---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqIRGKDISFIFQDPLssLNPTMKVGRqitevilqhekkskkeakeiaiNLLNDL--GIHEAEKR--------------- 147
Cdd:COG4136 73 --AEQRRIGILFQDDL--LFPHLSVGE----------------------NLAFALppTIGRAQRRarveqaleeaglagf 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 148 FEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVrEVADRVVV 227
Cdd:COG4136 127 ADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDA-PAAGRVLD 205
|
.
gi 446453403 228 M 228
Cdd:COG4136 206 L 206
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
5-242 |
6.02e-26 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 102.90 E-value: 6.02e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKEnskqEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEW 84
Cdd:cd03224 1 LEVENLNAGYGKS----QILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPR----SGSIRFDGRDITGLPPHER 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQiRGkdISFIFQdplsslnptmkvGRQI------TEVILqhekkskkeakeIAINLLNDLGIHEAEKR-FEQYP----- 152
Cdd:cd03224 73 AR-AG--IGYVPE------------GRRIfpeltvEENLL------------LGAYARRRAKRKARLERvYELFPrlker 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 153 -HQ----LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQnTSILLITHDLALVREVADRVVV 227
Cdd:cd03224 126 rKQlagtLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEG-VTILLVEQNARFALEIADRAYV 204
|
250
....*....|....*
gi 446453403 228 MYGGRIVEKGTIQEV 242
Cdd:cd03224 205 LERGRVVLEGTAAEL 219
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
24-242 |
6.02e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 104.45 E-value: 6.02e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLT--NLQEsewnqIRgKDISFIFQDPLS 101
Cdd:PRK13648 25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVK----SGEIFYNNQAITddNFEK-----LR-KHIGIVFQNPDN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 SLnptmkVGRQITEVI---LQHEKKSKKEAKEIAINLLNDLGIHEaekRFEQYPHQLSGGMRQRICLAIAFACHPKLVIA 178
Cdd:PRK13648 95 QF-----VGSIVKYDVafgLENHAVPYDEMHRRVSEALKQVDMLE---RADYEPNALSGGQKQRVAIAGVLALNPSVIIL 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 179 DEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREvADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK13648 167 DEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEI 229
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
4-243 |
7.76e-26 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 103.70 E-value: 7.76e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKDLTNLQESE 83
Cdd:PRK13548 2 MLEARNLSVRL----GGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSG----ELSPDSGEVRLNGRPLADWSPAE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRG-----KDISFIFQdplsslnptmkvgrqITEVI---LQHEKKSKKEAKEIAINLLNDLGIHEAEKRFeqYPhQL 155
Cdd:PRK13548 74 LARRRAvlpqhSSLSFPFT---------------VEEVVamgRAPHGLSRAEDDALVAAALAQVDLAHLAGRD--YP-QL 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 156 SGGMRQRICLAIAFA-CH-----PKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMY 229
Cdd:PRK13548 136 SGGEQQRVQLARVLAqLWepdgpPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLH 215
|
250
....*....|....
gi 446453403 230 GGRIVEKGTIQEVI 243
Cdd:PRK13548 216 QGRLVADGTPAEVL 229
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
22-247 |
1.32e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 103.62 E-value: 1.32e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVT---AQSIIGLNQESIQFDDGNISFESKDLTNLQesewnqirgKDISFIFQD 98
Cdd:PRK13639 16 EALKGINFKAEKGEMVALLGPNGAGKSTLflhFNGILKPTSGEVLIKGEPIKYDKKSLLEVR---------KTVGIVFQN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 PLSSL-NPTMKvgrqitevilqhekkskkeaKEIAINLLN-DLGIHEAEKR------------FEQY-PHQLSGGMRQRI 163
Cdd:PRK13639 87 PDDQLfAPTVE--------------------EDVAFGPLNlGLSKEEVEKRvkealkavgmegFENKpPHHLSGGQKKRV 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK13639 147 AIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLN-KEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVF 225
|
....
gi 446453403 244 GSPK 247
Cdd:PRK13639 226 SDIE 229
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
5-237 |
1.76e-25 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 101.59 E-value: 1.76e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQES---IQFDDGNISFESKDLTNLQE 81
Cdd:cd03269 1 LEVENVT----KRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDsgeVLFDGKPLDIAARNRIGYLP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 82 SEwnqiRGkdisfifqdplssLNPTMKVGRQItevilqhekkskkeakeIAINLLNDLGIHEAE-------KRFEQYPH- 153
Cdd:cd03269 77 EE----RG-------------LYPKMKVIDQL-----------------VYLAQLKGLKKEEARrridewlERLELSEYa 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 -----QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKqNTSILLITHDLALVREVADRVVVM 228
Cdd:cd03269 123 nkrveELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLL 201
|
....*....
gi 446453403 229 YGGRIVEKG 237
Cdd:cd03269 202 NKGRAVLYG 210
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
6-242 |
2.13e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 102.76 E-value: 2.13e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 6 SLENVTLAVEkeNSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGL---NQESIQFDDGNISFESKdltnlqes 82
Cdd:PRK13632 9 KVENVSFSYP--NSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLlkpQSGEIKIDGITISKENL-------- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 ewNQIRGKdISFIFQDPLSSLnptmkVGRQITEVI---LQHEKKSKKEAKEIAINLLNDLGIheaEKRFEQYPHQLSGGM 159
Cdd:PRK13632 79 --KEIRKK-IGIIFQNPDNQF-----IGATVEDDIafgLENKKVPPKKMKDIIDDLAKKVGM---EDYLDKEPQNLSGGQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 160 RQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLalvREV--ADRVVVMYGGRIVEKG 237
Cdd:PRK13632 148 KQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDM---DEAilADKVIVFSEGKLIAQG 224
|
....*
gi 446453403 238 TIQEV 242
Cdd:PRK13632 225 KPKEI 229
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
18-242 |
2.40e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 102.96 E-value: 2.40e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 18 NSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNL-QESEWNqIRGKdISFIF 96
Cdd:PRK13640 17 DSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGL----LLPDDNPNSKITVDGITLtAKTVWD-IREK-VGIVF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 97 QDPLSSLnptmkVGRQITEVI---LQHEKKSKKEAKEIAINLLNDLGIHEAEKrfeQYPHQLSGGMRQRICLAIAFACHP 173
Cdd:PRK13640 91 QNPDNQF-----VGATVGDDVafgLENRAVPRPEMIKIVRDVLADVGMLDYID---SEPANLSGGQKQRVAIAGILAVEP 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 174 KLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVrEVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK13640 163 KIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEI 230
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
20-252 |
3.57e-25 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 101.63 E-value: 3.57e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 20 KQEIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIG-LNQESIQfDDG--NISFESKDLTN-LQESEWNQIRGKdISFI 95
Cdd:COG4161 14 SHQALFDINLECPSGETLVLLGPSGAGKS----SLLRvLNLLETP-DSGqlNIAGHQFDFSQkPSEKAIRLLRQK-VGMV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 96 FQDplSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFeqyPHQLSGGMRQRICLAIAFACHPKL 175
Cdd:COG4161 88 FQQ--YNLWPHLTVMENLIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRF---PLHLSGGQQQRVAIARALMMEPQV 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 176 VIADEPTTALDVTIQKQIMGLLKERKEKQNTSIlLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIgspkHPYTK 252
Cdd:COG4161 163 LLFDEPTAALDPEITAQVVEIIRELSQTGITQV-IVTHEVEFARKVASQVVYMEKGRIIEQGDASHFT----QPQTE 234
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
5-262 |
7.35e-25 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 100.86 E-value: 7.35e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENskqeIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEW 84
Cdd:PRK11231 3 LRTENLTVGYGTKR----ILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQ----SGTVFLGDKPISMLSSRQL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqirGKDISFIFQDPLSslnPTmkvGRQITEVI-------LQHEKKSKKEAKEIAINLLNDLGIHE-AEKRFEQyphqLS 156
Cdd:PRK11231 75 ----ARRLALLPQHHLT---PE---GITVRELVaygrspwLSLWGRLSAEDNARVNQAMEQTRINHlADRRLTD----LS 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 157 GGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLItHDLALVREVADRVVVMYGGRIVEK 236
Cdd:PRK11231 141 GGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVL-HDLNQASRYCDHLVVLANGHVMAQ 219
|
250 260
....*....|....*....|....*.
gi 446453403 237 GTIQEVIgspkhpyTKSLLQAIPNMD 262
Cdd:PRK11231 220 GTPEEVM-------TPGLLRTVFDVE 238
|
|
| PhnT |
TIGR03258 |
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding ... |
23-257 |
8.14e-25 |
|
2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; This ATP-binding component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.
Pssm-ID: 132302 [Multi-domain] Cd Length: 362 Bit Score: 103.15 E-value: 8.14e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqFDDGNISFESKDLTNLQESEwnqirgKDISFIFQDplSS 102
Cdd:TIGR03258 20 VLDDLSLEIEAGELLALIGKSGCGKTTLLRAIAGFVKAA--GLTGRIAIADRDLTHAPPHK------RGLALLFQN--YA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 103 LNPTMKVGRQITEVILQHEKKSKKEAKEIAiNLLNDLGIHEAEKRfeqYPHQLSGGMRQRICLAIAFACHPKLVIADEPT 182
Cdd:TIGR03258 90 LFPHLKVEDNVAFGLRAQKMPKADIAERVA-DALKLVGLGDAAAH---LPAQLSGGMQQRIAIARAIAIEPDVLLLDEPL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 183 TALDVTIQKQIMGLLKE-RKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLLQA 257
Cdd:TIGR03258 166 SALDANIRANMREEIAAlHEELPELTILCVTHDQDDALTLADKAGIMKDGRLAAHGEPQALYDAPADGFAAEFLGA 241
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
4-234 |
8.52e-25 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 104.34 E-value: 8.52e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQEse 83
Cdd:COG3845 257 VLEVENLSV---RDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGL----RPPASGSIRLDGEDITGLSP-- 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wNQIRGKDISFIFQDPLSS-LNPTMKVgrqiTE-VILQHEKKSKKEAKEIainlLNDLGIHE-AEKRFEQY------PHQ 154
Cdd:COG3845 328 -RERRRLGVAYIPEDRLGRgLVPDMSV----AEnLILGRYRRPPFSRGGF----LDRKAIRAfAEELIEEFdvrtpgPDT 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 ----LSGGMRQRICLAIAFACHPKLVIADEPTTALDV----TIQKQimgLLKERKekQNTSILLITHDLALVREVADRVV 226
Cdd:COG3845 399 parsLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVgaieFIHQR---LLELRD--AGAAVLLISEDLDEILALSDRIA 473
|
....*...
gi 446453403 227 VMYGGRIV 234
Cdd:COG3845 474 VMYEGRIV 481
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
4-270 |
1.01e-24 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 102.99 E-value: 1.01e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESE 83
Cdd:PRK11607 19 LLEIRNLT----KSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPT----AGQIMLDGVDLSHVPPYQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnqirgKDISFIFQDplSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAiNLLNDLGIHEAEKRfeqYPHQLSGGMRQRI 163
Cdd:PRK11607 91 ------RPINMMFQS--YALFPHMTVEQNIAFGLKQDKLPKAEIASRVN-EMLGLVHMQEFAKR---KPHQLSGGQRQRV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK11607 159 ALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIY 238
|
250 260
....*....|....*....|....*..
gi 446453403 244 gspKHPYTKSLLQAIPNMDDAEKVLRA 270
Cdd:PRK11607 239 ---EHPTTRYSAEFIGSVNVFEGVLKE 262
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
24-244 |
1.03e-24 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 104.50 E-value: 1.03e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISF----ESKDLTNLQESEwnqiRG---KDISFIF 96
Cdd:TIGR03269 300 VDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPT----SGEVNVrvgdEWVDMTKPGPDG----RGrakRYIGILH 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 97 QDplSSLNPTMKVGRQITEVIlqHEKKSKKEAKEIAINLLNDLGIHE--AEKRFEQYPHQLSGGMRQRICLAIAFACHPK 174
Cdd:TIGR03269 372 QE--YDLYPHRTVLDNLTEAI--GLELPDELARMKAVITLKMVGFDEekAEEILDKYPDELSEGERHRVALAQVLIKEPR 447
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446453403 175 LVIADEPTTALD-VTIQKQIMGLLKERKEKQNTSIlLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIG 244
Cdd:TIGR03269 448 IVILDEPTGTMDpITKVDVTHSILKAREEMEQTFI-IVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEIVE 517
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-234 |
1.33e-24 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 100.55 E-value: 1.33e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKE--NSKQeIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKDLTNLQES 82
Cdd:COG1101 2 LELKNLSKTFNPGtvNEKR-ALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAG----SLPPDSGSILIDGKDVTKLPEY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EwnqiRGKDISFIFQDPLSSLNPTMkvgrQITEVILQHEKKSKKEAKEIAIN---------LLNDLGIhEAEKRFEQYPH 153
Cdd:COG1101 77 K----RAKYIGRVFQDPMMGTAPSM----TIEENLALAYRRGKRRGLRRGLTkkrrelfreLLATLGL-GLENRLDTKVG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDL--ALvrEVADRVVVMYGG 231
Cdd:COG1101 148 LLSGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMeqAL--DYGNRLIMMHEG 225
|
...
gi 446453403 232 RIV 234
Cdd:COG1101 226 RII 228
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
24-248 |
1.37e-24 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 99.46 E-value: 1.37e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNlqesewnqiRGKDISFIFQDplSSL 103
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPT----SGGVILEGKQITE---------PGPDRMVVFQN--YSL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQIT----EVILQHEKKSKKEAKEIAINLLNdLGiHEAEKRfeqyPHQLSGGMRQRICLAIAFACHPKLVIAD 179
Cdd:TIGR01184 66 LPWLTVRENIAlavdRVLPDLSKSERRAIVEEHIALVG-LT-EAADKR----PGQLSGGMKQRVAIARALSIRPKVLLLD 139
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 180 EPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV-IGSPKH 248
Cdd:TIGR01184 140 EPFGALDALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEVpFPRPRD 209
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
27-250 |
2.36e-24 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 101.73 E-value: 2.36e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFeskDLTNLQESEWN---QIRGKDISFIFQDplSSL 103
Cdd:TIGR02142 16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGL----TRPDEGEIVL---NGRTLFDSRKGiflPPEKRRIGYVFQE--ARL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVgRQITEVILQHEKKSKKEAKEIAINLLndLGIheaEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTT 183
Cdd:TIGR02142 87 FPHLSV-RGNLRYGMKRARPSERRISFERVIEL--LGI---GHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 184 ALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPY 250
Cdd:TIGR02142 161 ALDDPRKYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPW 227
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
5-247 |
4.47e-24 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 98.56 E-value: 4.47e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNL----- 79
Cdd:COG1137 4 LEAENLV----KSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGL----VKPDSGRIFLDGEDITHLpmhkr 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 80 ---------QESewnqirgkdiSfIFQDplsslnptMKVGRQItEVILQHEKKSKKEAKEIAINLLNDLGIheaEKRFEQ 150
Cdd:COG1137 76 arlgigylpQEA----------S-IFRK--------LTVEDNI-LAVLELRKLSKKEREERLEELLEEFGI---THLRKS 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 151 YPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALD-VTIQ--KQIMGLLKERkekqNTSIlLIT-HDlalVRE---VAD 223
Cdd:COG1137 133 KAYSLSGGERRRVEIARALATNPKFILLDEPFAGVDpIAVAdiQKIIRHLKER----GIGV-LITdHN---VREtlgICD 204
|
250 260
....*....|....*....|....
gi 446453403 224 RVVVMYGGRIVEKGTIQEVIGSPK 247
Cdd:COG1137 205 RAYIISEGKVLAEGTPEEILNNPL 228
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
22-241 |
5.02e-24 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 97.83 E-value: 5.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTnlqeSEWNQIRgKDISFIFQDPls 101
Cdd:cd03265 14 EAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTL----LKPTSGRATVAGHDVV----REPREVR-RRIGIVFQDL-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 SLNPTMkVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQYphqLSGGMRQRICLAIAFACHPKLVIADEP 181
Cdd:cd03265 83 SVDDEL-TGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKT---YSGGMRRRLEIARSLVHRPEVLFLDEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 182 TTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQE 241
Cdd:cd03265 159 TIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEE 218
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
7-237 |
5.63e-24 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 97.66 E-value: 5.63e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 7 LENVTLAVEkeNSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEwnq 86
Cdd:cd03245 5 FRNVSFSYP--NQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPT----SGSVLLDGTDIRQLDPAD--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 87 IRgKDISFIFQDPL---SSL--NPTMKVGRQITEVILQhekkskkeakeiAINLLndlGIHEAEKRfeqYPH-------- 153
Cdd:cd03245 76 LR-RNIGYVPQDVTlfyGTLrdNITLGAPLADDERILR------------AAELA---GVTDFVNK---HPNgldlqige 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 ---QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQntSILLITHDLALVrEVADRVVVMYG 230
Cdd:cd03245 137 rgrGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDK--TLIIITHRPSLL-DLVDRIIVMDS 213
|
....*..
gi 446453403 231 GRIVEKG 237
Cdd:cd03245 214 GRIVADG 220
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
24-241 |
9.76e-24 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 99.00 E-value: 9.76e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTnlqeSEWNQIRgKDISFIFQDPLSSL 103
Cdd:TIGR01188 9 VDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTL----LRPTSGTARVAGYDVV----REPRKVR-RSIGIVPQYASVDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTmkvGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSGGMRQRICLAIAFACHPKLVIADEPTT 183
Cdd:TIGR01188 80 DLT---GRENLEMMGRLYGLPKDEAEERAEELLELFELGEAADR---PVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTT 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 184 ALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYGGRIVEKGTIQE 241
Cdd:TIGR01188 154 GLDPRTRRAIWDYIRALKEEGVT-ILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEE 210
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
21-266 |
1.04e-23 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 98.24 E-value: 1.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 21 QEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFD-DGNISFESKDLTNLQESEWNQIRgkdISFIFQDP 99
Cdd:PRK14271 34 KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRySGDVLLGGRSIFNYRDVLEFRRR---VGMLFQRP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 lsslNP-TMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEK-RFEQYPHQLSGGMRQRICLAIAFACHPKLVI 177
Cdd:PRK14271 111 ----NPfPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAVKdRLSDSPFRLSGGQQQLLCLARTLAVNPEVLL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 178 ADEPTTALDVTIQKQIMGLLKERKEKqnTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTKSLLQA 257
Cdd:PRK14271 187 LDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAETARYVAG 264
|
250
....*....|
gi 446453403 258 IP-NMDDAEK 266
Cdd:PRK14271 265 LSgDVKDAKR 274
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
5-243 |
1.13e-23 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 101.36 E-value: 1.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEkeNSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIqfddGNISFESKDLTNlqeseW 84
Cdd:COG4618 331 LSVENLTVVPP--GSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTA----GSVRLDGADLSQ-----W 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIR-GKDISFIFQDPlsSLNP-TmkvgrqitevilqhekkskkeakeIAINL--LNDL------------GIHEAEKRF 148
Cdd:COG4618 400 DREElGRHIGYLPQDV--ELFDgT------------------------IAENIarFGDAdpekvvaaaklaGVHEMILRL 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 149 EQ-Y-------PHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVRe 220
Cdd:COG4618 454 PDgYdtrigegGARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKA-RGATVVVITHRPSLLA- 531
|
250 260
....*....|....*....|...
gi 446453403 221 VADRVVVMYGGRIVEKGTIQEVI 243
Cdd:COG4618 532 AVDKLLVLRDGRVQAFGPRDEVL 554
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
5-247 |
1.22e-23 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 97.23 E-value: 1.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVtlavEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLqesEW 84
Cdd:cd03218 1 LRAENL----SKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGL----VKPDSGKILLDGQDITKL---PM 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRGKDISFIFQDPlsSLNPTMKVGRQItEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKrfeQYPHQLSGGMRQRIC 164
Cdd:cd03218 70 HKRARLGIGYLPQEA--SIFRKLTVEENI-LAVLEIRGLSKKEREEKLEELLEEFHITHLRK---SKASSLSGGERRRVE 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 165 LAIAFACHPKLVIADEPTTALD-VTIQ--KQIMGLLKERkekqNTSILLITHDlalVRE---VADRVVVMYGGRIVEKGT 238
Cdd:cd03218 144 IARALATNPKFLLLDEPFAGVDpIAVQdiQKIIKILKDR----GIGVLITDHN---VREtlsITDRAYIIYEGKVLAEGT 216
|
....*....
gi 446453403 239 IQEVIGSPK 247
Cdd:cd03218 217 PEEIAANEL 225
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
39-250 |
1.76e-23 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 98.72 E-value: 1.76e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 39 LVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQEsewnQIRGkdISFIFQDplSSLNPTMKVGRQITEVIL 118
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGF----EQPDSGSIMLDGEDVTNVPP----HLRH--INMVFQS--YALFPHMTVEENVAFGLK 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 119 QHEKKSKKeakeIAINLLNDLGIHEAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLK 198
Cdd:TIGR01187 69 MRKVPRAE----IKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELK 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446453403 199 ERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPY 250
Cdd:TIGR01187 145 TIQEQLGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLF 196
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
27-238 |
1.79e-23 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 97.01 E-value: 1.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSvtaqSIIG-LN-QESIQFDDGNISFESKDL-TNLQESEWNQIRgKDISFIFQDplSSL 103
Cdd:PRK11124 21 ITLDCPQGETLVLLGPSGAGKS----SLLRvLNlLEMPRSGTLNIAGNHFDFsKTPSDKAIRELR-RNVGMVFQQ--YNL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFeqyPHQLSGGMRQRICLAIAFACHPKLVIADEPTT 183
Cdd:PRK11124 94 WPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRF---PLHLSGGQQQRVAIARALMMEPQVLLFDEPTA 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 184 ALDVTIQKQIMGLLKERKEKQNTSIlLITHDLALVREVADRVVVMYGGRIVEKGT 238
Cdd:PRK11124 171 ALDPEITAQIVSIIRELAETGITQV-IVTHEVEVARKTASRVVYMENGHIVEQGD 224
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
4-243 |
1.90e-23 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 97.11 E-value: 1.90e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESE 83
Cdd:COG4559 1 MLEAENLSVRL----GGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGE----LTPSSGEVRLNGRPLAAWSPWE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRG-----KDISFifqdPLSSLnptmkvgrqitEVI---LQHEKKSKKEAKEIAINLLNDLGIHEAEKRFeqYPhQL 155
Cdd:COG4559 73 LARRRAvlpqhSSLAF----PFTVE-----------EVValgRAPHGSSAAQDRQIVREALALVGLAHLAGRS--YQ-TL 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 156 SGGMRQRICLAIAFA-------CHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVM 228
Cdd:COG4559 135 SGGEQQRVQLARVLAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLAR-RGGGVVAVLHDLNLAAQYADRILLL 213
|
250
....*....|....*
gi 446453403 229 YGGRIVEKGTIQEVI 243
Cdd:COG4559 214 HQGRLVAQGTPEEVL 228
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
6-243 |
2.09e-23 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 100.81 E-value: 2.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 6 SLENVTLAVEKEN------SKQEIVKHVSFSINEGEIVALVGESGSGKSVTaqsiIGLNQESIQFDDGNISFESKDLTNL 79
Cdd:PRK13657 327 DLGRVKGAVEFDDvsfsydNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTL----INLLQRVFDPQSGRILIDGTDIRTV 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 80 QESewnQIRgKDISFIFQDPL---SSLNPTMKVGRQ-ITEVILQHEKKSKKEAKEIAINLlNDLGIHEAEKrfeqyPHQL 155
Cdd:PRK13657 403 TRA---SLR-RNIAVVFQDAGlfnRSIEDNIRVGRPdATDEEMRAAAERAQAHDFIERKP-DGYDTVVGER-----GRQL 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 156 SGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSIllITHDLALVREvADRVVVMYGGRIVE 235
Cdd:PRK13657 473 SGGERQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDELMKGRTTFI--IAHRLSTVRN-ADRILVFDNGRVVE 549
|
....*...
gi 446453403 236 KGTIQEVI 243
Cdd:PRK13657 550 SGSFDELV 557
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
4-247 |
2.54e-23 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 96.20 E-value: 2.54e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLqesE 83
Cdd:COG0410 3 MLEVENLHAGY----GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGL----LPPRSGSIRFDGEDITGL---P 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRGKDISF------IFqdplsslnPTMKVgrqiTEvilqhekkskkeakeiaiNLL-------NDLGIHEAEKR-FE 149
Cdd:COG0410 72 PHRIARLGIGYvpegrrIF--------PSLTV----EE------------------NLLlgayarrDRAEVRADLERvYE 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 150 QYP------HQ----LSGGMRQRicLAIAFA--CHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLAL 217
Cdd:COG0410 122 LFPrlkerrRQragtLSGGEQQM--LAIGRAlmSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNR-EGVTILLVEQNARF 198
|
250 260 270
....*....|....*....|....*....|
gi 446453403 218 VREVADRVVVMYGGRIVEKGTIQEVIGSPK 247
Cdd:COG0410 199 ALEIADRAYVLERGRIVLEGTAAELLADPE 228
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
5-243 |
2.78e-23 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 100.50 E-value: 2.78e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKDLTNlqeseW 84
Cdd:TIGR01842 317 LSVENVTIV--PPGGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVG----IWPPTSGSVRLDGADLKQ-----W 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIR-GKDISFIFQDplSSLNPTmkvgrQITEVILQHEKKSKKEAKEIAINLLndlGIHEAEKRFEQ-YPHQ-------L 155
Cdd:TIGR01842 386 DRETfGKHIGYLPQD--VELFPG-----TVAENIARFGENADPEKIIEAAKLA---GVHELILRLPDgYDTVigpggatL 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 156 SGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVrEVADRVVVMYGGRIVE 235
Cdd:TIGR01842 456 SGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALK-ARGITVVVITHRPSLL-GCVDKILVLQDGRIAR 533
|
....*...
gi 446453403 236 KGTIQEVI 243
Cdd:TIGR01842 534 FGERDEVL 541
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
4-228 |
2.86e-23 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 95.24 E-value: 2.86e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKEnskqEIVKHVSFSINEGEIVALVGESGSGKSvTA-QSIIGLnqesIQFDDGNISFESKDLTNLQES 82
Cdd:COG4133 2 MLEAENLSCRRGER----LLFSGLSFTLAAGEALALTGPNGSGKT-TLlRILAGL----LPPSAGEVLWNGEPIRDARED 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 ewnqiRGKDISFIFQDPLssLNPTMKVGRQITevILQHEKKSKKEAKEIAiNLLNDLGIHEAEkrfEQYPHQLSGGMRQR 162
Cdd:COG4133 73 -----YRRRLAYLGHADG--LKPELTVRENLR--FWAALYGLRADREAID-EALEAVGLAGLA---DLPVRQLSAGQKRR 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVRevADRVVVM 228
Cdd:COG4133 140 VALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLA-RGGAVLLTTHQPLELA--AARVLDL 202
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
22-245 |
3.16e-23 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 96.02 E-value: 3.16e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTnLQESEWNQirgKDISFIFQ---- 97
Cdd:cd03252 16 VILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVP----ENGRVLVDGHDLA-LADPAWLR---RQVGVVLQenvl 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 ------DPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIheaekrfeqyphQLSGGMRQRICLAIAFAC 171
Cdd:cd03252 88 fnrsirDNIALADPGMSMERVIEAAKLAGAHDFISELPEGYDTIVGEQGA------------GLSGGQRQRIAIARALIH 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 172 HPKLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDLALVREvADRVVVMYGGRIVEKGTIQEVIGS 245
Cdd:cd03252 156 NPRILIFDEATSALDYESEHAIMRNM--HDICAGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAE 226
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-260 |
3.36e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 97.11 E-value: 3.36e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLAVeKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTnlQ 80
Cdd:PRK13650 1 MSNIIEVKNLTFKY-KEDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGL----LEAESGQIIIDGDLLT--E 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 ESEWNqIRGKdISFIFQDPLSSLnptmkVGRQITEVI---LQHEKKSKKEAKEIAINLLNDLGIHEAEKRfeqYPHQLSG 157
Cdd:PRK13650 74 ENVWD-IRHK-IGMVFQNPDNQF-----VGATVEDDVafgLENKGIPHEEMKERVNEALELVGMQDFKER---EPARLSG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 158 GMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLalvREVA--DRVVVMYGGRIVE 235
Cdd:PRK13650 144 GQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDL---DEVAlsDRVLVMKNGQVES 220
|
250 260 270
....*....|....*....|....*....|...
gi 446453403 236 KGTIQEVIGSPKH--------PYTKSLLQAIPN 260
Cdd:PRK13650 221 TSTPRELFSRGNDllqlgldiPFTTSLVQSLRQ 253
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
21-243 |
3.59e-23 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 96.07 E-value: 3.59e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 21 QEIVKHVSFSINEGEIVALVGESGSGKSVTAQSII---GLNQESIQFDDGNIsfesKDLtNLQEsewnqIRGKdISFIFQ 97
Cdd:cd03249 16 VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLErfyDPTSGEILLDGVDI----RDL-NLRW-----LRSQ-IGLVSQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 DPLssLNPTmkvgrQITEVILQHEKKSKKEAKEIAINLLNdlgIHE-AEKRFEQY-----PH--QLSGGMRQRICLAIAF 169
Cdd:cd03249 85 EPV--LFDG-----TIAENIRYGKPDATDEEVEEAAKKAN---IHDfIMSLPDGYdtlvgERgsQLSGGQKQRIAIARAL 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 170 ACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkqNTSILLITHDLALVREvADRVVVMYGGRIVEKGTIQEVI 243
Cdd:cd03249 155 LRNPKILLLDEATSALDAESEKLVQEALDRAMK--GRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQGTHDELM 225
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
5-233 |
4.17e-23 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 94.21 E-value: 4.17e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEkeNSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEW 84
Cdd:cd03246 1 LEVENVSFRYP--GAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPT----SGRVRLDGADISQWDPNEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqirGKDISFIFQDplsslnptmkvgrqiteVILqhekkskkEAKEIAINLLndlgiheaekrfeqyphqlSGGMRQRIC 164
Cdd:cd03246 75 ----GDHVGYLPQD-----------------DEL--------FSGSIAENIL-------------------SGGQRQRLG 106
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSIlLITHDLALVREvADRVVVMYGGRI 233
Cdd:cd03246 107 LARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAAGATRI-VIAHRPETLAS-ADRILVLEDGRV 173
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
8-243 |
4.67e-23 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 95.37 E-value: 4.67e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 8 ENVTLAVEKENSkqeIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFESKDLTNLQESEWNqi 87
Cdd:cd03254 6 ENVNFSYDEKKP---VLKDINFSIKPGETVAIVGPTGAGKT----TLINLLMRFYDPQKGQILIDGIDIRDISRKSLR-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 88 rgKDISFIFQDPL---SSLNPTMKVGRQIT--EVIlqhekkskkeakeiaINLLNDLGIHEAEKRFEQ-YPHQ------- 154
Cdd:cd03254 77 --SMIGVVLQDTFlfsGTIMENIRLGRPNAtdEEV---------------IEAAKEAGAHDFIMKLPNgYDTVlgenggn 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAFACHPKLVIADEPTTALDV----TIQKQIMGLLKERkekqnTSIlLITHDLALVREvADRVVVMYG 230
Cdd:cd03254 140 LSQGERQLLAIARAMLRDPKILILDEATSNIDTetekLIQEALEKLMKGR-----TSI-IIAHRLSTIKN-ADKILVLDD 212
|
250
....*....|...
gi 446453403 231 GRIVEKGTIQEVI 243
Cdd:cd03254 213 GKIIEEGTHDELL 225
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
5-237 |
6.79e-23 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 94.13 E-value: 6.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKEnskqEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIQFDDGNISFESKDLTNLQESEw 84
Cdd:cd03217 1 LEIKDLHVSVGGK----EILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGH--PKYEVTEGEILFKGEDITDLPPEE- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqiRGKDISFI-FQDPLsslnptmkvgrQITEVILqhekkskkeakeiaINLLNDLGIheaekrfeqyphQLSGGMRQRI 163
Cdd:cd03217 74 ---RARLGIFLaFQYPP-----------EIPGVKN--------------ADFLRYVNE------------GFSGGEKKRN 113
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKqNTSILLITHD---LALVRevADRVVVMYGGRIVEKG 237
Cdd:cd03217 114 EILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREE-GKSVLIITHYqrlLDYIK--PDRVHVLYDGRIVKSG 187
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
5-228 |
6.93e-23 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 98.90 E-value: 6.93e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENskqEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:TIGR02857 322 LEFSGVSVAYPGRR---PALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGF----VDPTEGSIAVNGVPLADADADSW 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqirGKDISFIFQdplsslNPTMKVGrQITEVILQHEKKSKKEAKEIAinlLNDLGIHEAEKRFEQY--------PHQLS 156
Cdd:TIGR02857 395 ----RDQIAWVPQ------HPFLFAG-TIAENIRLARPDASDAEIREA---LERAGLDEFVAALPQGldtpigegGAGLS 460
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446453403 157 GGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDLALVREvADRVVVM 228
Cdd:TIGR02857 461 GGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEAL--RALAQGRTVLLVTHRLALAAL-ADRIVVL 529
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
13-252 |
6.94e-23 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 95.68 E-value: 6.94e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 13 AVEKEN-----SKQEIVKHVSFSINEGEIVALVGESGSGKSV---TAQSIIGLNQESIQfdDGNISFESKDLTNlQESEW 84
Cdd:PRK14267 4 AIETVNlrvyyGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTllrTFNRLLELNEEARV--EGEVRLFGRNIYS-PDVDP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRgKDISFIFQDPlsslNP--------TMKVGRQITEVILQHEKKSKKEAKEIAINLLNDlgihEAEKRFEQYPHQLS 156
Cdd:PRK14267 81 IEVR-REVGMVFQYP----NPfphltiydNVAIGVKLNGLVKSKKELDERVEWALKKAALWD----EVKDRLNDYPSNLS 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 157 GGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkqNTSILLITHDLALVREVADRVVVMYGGRIVEK 236
Cdd:PRK14267 152 GGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKK--EYTIVLVTHSPAQAARVSDYVAFLYLGKLIEV 229
|
250
....*....|....*.
gi 446453403 237 GTIQEVIGSPKHPYTK 252
Cdd:PRK14267 230 GPTRKVFENPEHELTE 245
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
24-228 |
1.10e-22 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 94.42 E-value: 1.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESK----DLTNLQESEWNQIRGKDISFIFQdp 99
Cdd:COG4778 27 LDGVSFSVAAGECVALTGPSGAGKSTLLKCIYG----NYLPDSGSILVRHDggwvDLAQASPREILALRRRTIGYVSQ-- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 lsSLN-----PTMKVgrqiteVI--LQHEKKSKKEAKEIAINLLNDLGIheAEKRFEQYPHQLSGGMRQRICLAIAFACH 172
Cdd:COG4778 101 --FLRviprvSALDV------VAepLLERGVDREEARARARELLARLNL--PERLWDLPPATFSGGEQQRVNIARGFIAD 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 173 PKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVM 228
Cdd:COG4778 171 PPLLLLDEPTASLDAANRAVVVELIEEAKA-RGTAIIGIFHDEEVREAVADRVVDV 225
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
22-252 |
1.31e-22 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 94.59 E-value: 1.31e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQ---SIIGLNQESIQfdDGNISFESKDLTNLQESEWNqirgKDISFIFQ- 97
Cdd:PRK14247 17 EVLDGVNLEIPDNTITALMGPSGSGKSTLLRvfnRLIELYPEARV--SGEVYLDGQDIFKMDVIELR----RRVQMVFQi 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 -DPLSSLN--PTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDlgihEAEKRFEQYPHQLSGGMRQRICLAIAFACHPK 174
Cdd:PRK14247 91 pNPIPNLSifENVALGLKLNRLVKSKKELQERVRWALEKAQLWD----EVKDRLDAPAGKLSGGQQQRLCIARALAFQPE 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 175 LVIADEPTTALDVTIQKQIMGLLKERkeKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTK 252
Cdd:PRK14247 167 VLLADEPTANLDPENTAKIESLFLEL--KKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHELTE 242
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
27-242 |
2.00e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 94.81 E-value: 2.00e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLN---QESIQFDDGNISFESKDltnlqeSEWNQIRgKDISFIFQDPLSSL 103
Cdd:PRK13649 26 VNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHvptQGSVRVDDTLITSTSKN------KDIKQIR-KKVGLVFQFPESQL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 nptmkvgrqITEVIL-------QHEKKSKKEAKEIAINLLNDLGIheAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLV 176
Cdd:PRK13649 99 ---------FEETVLkdvafgpQNFGVSQEEAEALAREKLALVGI--SESLFEKNPFELSGGQMRRVAIAGILAMEPKIL 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 177 IADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK13649 168 VLDEPTAGLDPKGRKELMTLFKKLHQSGMT-IVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDI 232
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
5-237 |
2.51e-22 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 91.99 E-value: 2.51e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEkeNSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKDLTNLQESew 84
Cdd:cd03247 1 LSINNVSFSYP--EQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTG----DLKPQQGEITLDGVPVSDLEKA-- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqiRGKDISFIFQDPlsslnptmkvgrqitevilqhekkskkeaKEIAINLLNDLGIheaekrfeqyphQLSGGMRQRIC 164
Cdd:cd03247 73 ---LSSLISVLNQRP-----------------------------YLFDTTLRNNLGR------------RFSGGERQRLA 108
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkqNTSILLITHDLALVrEVADRVVVMYGGRIVEKG 237
Cdd:cd03247 109 LARILLQDAPIVLLDEPTVGLDPITERQLLSLIFEVLK--DKTLIWITHHLTGI-EHMDKILFLENGKIIMQG 178
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
2-259 |
3.25e-22 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 94.92 E-value: 3.25e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 2 GQLLSLENVTlAVEKENSKQEIV--KHVSFSINEGEIVALVGESGSGKSVTAQSIIGL---NQESIQFDDgnISFESKDL 76
Cdd:PRK13631 19 DIILRVKNLY-CVFDEKQENELValNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLiksKYGTIQVGD--IYIGDKKN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 77 TNLQESEWNQIRGKD-------ISFIFQDPLSSL-NPTMKVGRQITEVILQhekKSKKEAKEIAINLLNDLGIHEAekRF 148
Cdd:PRK13631 96 NHELITNPYSKKIKNfkelrrrVSMVFQFPEYQLfKDTIEKDIMFGPVALG---VKKSEAKKLAKFYLNKMGLDDS--YL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 149 EQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVM 228
Cdd:PRK13631 171 ERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAK-ANNKTVFVITHTMEHVLEVADEVIVM 249
|
250 260 270
....*....|....*....|....*....|.
gi 446453403 229 YGGRIVEKGTIQEVIGSPkHPYTKSLLQAIP 259
Cdd:PRK13631 250 DKGKILKTGTPYEIFTDQ-HIINSTSIQVPR 279
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
5-247 |
4.47e-22 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 95.17 E-value: 4.47e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNlqesew 84
Cdd:PRK11432 7 VVLKNIT----KRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPT----EGQIFIDGEDVTH------ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRGKDISFIFQDplSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINL-LNDLGIHEaekrfEQYPHQLSGGMRQRI 163
Cdd:PRK11432 73 RSIQQRDICMVFQS--YALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALeLVDLAGFE-----DRYVDQISGGQQQRV 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK11432 146 ALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELY 225
|
....
gi 446453403 244 GSPK 247
Cdd:PRK11432 226 RQPA 229
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
21-252 |
6.26e-22 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 93.19 E-value: 6.26e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 21 QEIVKHVSFSINEGEIVALVGESGSGKSVTAQ---SIIGLNQESIQFDdGNISFESKDLTNLQESEWNqirgKDISFIFQ 97
Cdd:PRK14246 23 KAILKDITIKIPNNSIFGIMGPSGSGKSTLLKvlnRLIEIYDSKIKVD-GKVLYFGKDIFQIDAIKLR----KEVGMVFQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 DPlsSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGI-HEAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLV 176
Cdd:PRK14246 98 QP--NPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLwKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVL 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 177 IADEPTTALDVTIQKQIMGLLKERKEKqnTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTK 252
Cdd:PRK14246 176 LMDEPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTE 249
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
5-238 |
6.44e-22 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 92.82 E-value: 6.44e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIqfDDGNISFESKDLTNLQESEw 84
Cdd:COG0396 1 LEIKNLHVSVEG----KEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKYEV--TSGSILLDGEDILELSPDE- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqiR-GKDISFIFQDPLSSlnPTMKVG---RQITEVILQHEKKSKKEAKEIAiNLLNDLGI-HEAEKR-----Feqyphq 154
Cdd:COG0396 74 ---RaRAGIFLAFQYPVEI--PGVSVSnflRTALNARRGEELSAREFLKLLK-EKMKELGLdEDFLDRyvnegF------ 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 lSGGMRQRICLAIAFACHPKLVIADEPTTALDV-TIQKQIMGLLKERKEkqNTSILLITHDLALVREV-ADRVVVMYGGR 232
Cdd:COG0396 142 -SGGEKKRNEILQMLLLEPKLAILDETDSGLDIdALRIVAEGVNKLRSP--DRGILIITHYQRILDYIkPDFVHVLVDGR 218
|
....*.
gi 446453403 233 IVEKGT 238
Cdd:COG0396 219 IVKSGG 224
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
25-242 |
1.42e-21 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 95.09 E-value: 1.42e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 25 KHVSFSINEGEIVALVGESGSGKSvTAQSII-GLnqesIQFDDGNISFESK--DLTNLQESewnQIRGkdISFIFQDPls 101
Cdd:COG1129 21 DGVSLELRPGEVHALLGENGAGKS-TLMKILsGV----YQPDSGEILLDGEpvRFRSPRDA---QAAG--IAIIHQEL-- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 SLNPTMKV------GRQITE-VILQHEKKSKKeakeiAINLLNDLGIHEAekrfeqyPHQ----LSGGMRQRICLAIAFA 170
Cdd:COG1129 89 NLVPNLSVaeniflGREPRRgGLIDWRAMRRR-----ARELLARLGLDID-------PDTpvgdLSVAQQQLVEIARALS 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 171 CHPKLVIADEPTTALDVT-IQK--QIMGLLKErkekQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:COG1129 157 RDARVLILDEPTASLTEReVERlfRIIRRLKA----QGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAEL 227
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
19-251 |
1.83e-21 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 91.76 E-value: 1.83e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 19 SKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSI--IG-LNQE-----SIQFDDGNISFESKDLTNLQesewnqirgK 90
Cdd:PRK14239 16 NKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNdLNPEvtitgSIVYNGHNIYSPRTDTVDLR---------K 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 91 DISFIFQDPlsslNP-TMKV------GRQITEVILQHEKKSKKEAKEIAINLLNdlgihEAEKRFEQYPHQLSGGMRQRI 163
Cdd:PRK14239 87 EIGMVFQQP----NPfPMSIyenvvyGLRLKGIKDKQVLDEAVEKSLKGASIWD-----EVKDRLHDSALGLSGGQQQRV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQntSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK14239 158 CIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDY--TMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMF 235
|
....*...
gi 446453403 244 GSPKHPYT 251
Cdd:PRK14239 236 MNPKHKET 243
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
4-280 |
3.08e-21 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 93.09 E-value: 3.08e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQESE 83
Cdd:PRK09452 14 LVELRGIS----KSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETP----DSGRIMLDGQDITHVPAEN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnqirgKDISFIFQDplSSLNPTMKV------GRQITEVilqhekkskkEAKEIAINLLNDLGIHEAEKRFEQYPHQLSG 157
Cdd:PRK09452 86 ------RHVNTVFQS--YALFPHMTVfenvafGLRMQKT----------PAAEITPRVMEALRMVQLEEFAQRKPHQLSG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 158 GMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDlalvREVA----DRVVVMYGGRI 233
Cdd:PRK09452 148 GQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHD----QEEAltmsDRIVVMRDGRI 223
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 234 VEKGTIQEVIGSPKHPYTKSLLQAIpNMDDA-------EKVLRA-IEGTTPSIET 280
Cdd:PRK09452 224 EQDGTPREIYEEPKNLFVARFIGEI-NIFDAtvierldEQRVRAnVEGRECNIYV 277
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-252 |
3.28e-21 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 90.87 E-value: 3.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLAVEKEN---SKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQE--------SIQFDDGNI 69
Cdd:COG1117 1 MTAPASTLEPKIEVRNLNvyyGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLipgarvegEILLDGEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 70 SFESKDLTNLqesewnqiRgKDISFIFQDPlsslNP----------------TMKVGRQITEvilqhekkskkeakeIAI 133
Cdd:COG1117 81 YDPDVDVVEL--------R-RRVGMVFQKP----NPfpksiydnvayglrlhGIKSKSELDE---------------IVE 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 134 NLLNDLGI-HEAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKErkEKQNTSILLIT 212
Cdd:COG1117 133 ESLRKAALwDEVKDRLKKSALGLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILE--LKKDYTIVIVT 210
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 446453403 213 HDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPKHPYTK 252
Cdd:COG1117 211 HNMQQAARVSDYTAFFYLGELVEFGPTEQIFTNPKDKRTE 250
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
4-237 |
3.50e-21 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 90.12 E-value: 3.50e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKD-LTNLQES 82
Cdd:cd03266 1 MITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGL----LEPDAGFATVDGFDvVKEPAEA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNqirgkdISFIFQDplSSLNPTMKVGRQITEVILQHEKKSKKEAKeiAINLLND-LGIHE-AEKRFEQyphqLSGGMR 160
Cdd:cd03266 77 RRR------LGFVSDS--TGLYDRLTARENLEYFAGLYGLKGDELTA--RLEELADrLGMEElLDRRVGG----FSTGMR 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03266 143 QKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRALGKC-ILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| oligo_HPY |
TIGR01727 |
oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model ... |
232-318 |
3.85e-21 |
|
oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; This model represents a domain found in the C-terminal regions of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 213647 [Multi-domain] Cd Length: 87 Bit Score: 86.26 E-value: 3.85e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 232 RIVEKGTIQEVIGSPKHPYTKSLLQAIPNMDDAEKVLRAIEGTTPSIETLNSfGCPFVNRCPVAIQECIHRFPERTTYSA 311
Cdd:TIGR01727 1 KIVETGPAEEIFKNPLHPYTKALLSAIPTIKKRDRKLISIPGEVPSLINLPS-GCRFYPRCPYAQDECRKEPPALVEIAE 79
|
....*..
gi 446453403 312 EHSSHCW 318
Cdd:TIGR01727 80 GHRVACH 86
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
19-237 |
4.46e-21 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 89.47 E-value: 4.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 19 SKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIQFddGNISFESKDLTNLQESEwnqirgKDISFIFQD 98
Cdd:cd03298 9 SYGEQPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGF--ETPQS--GRVLINGVDVTAAPPAD------RPVSMLFQE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 P-----LS-------SLNPTMK---VGRQITEVILQHekkskkeakeiainllndLGIHEAEKRFeqyPHQLSGGMRQRI 163
Cdd:cd03298 79 NnlfahLTveqnvglGLSPGLKltaEDRQAIEVALAR------------------VGLAGLEKRL---PGELSGGERQRV 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 164 CLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKE-RKEKQNTsILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03298 138 ALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDlHAETKMT-VLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
27-233 |
4.51e-21 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 89.77 E-value: 4.51e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEWNQIRGKdISFIFQDplSSLNPT 106
Cdd:cd03292 20 INISISAGEFVFLVGPSGAGKSTLLKLIYKEELPT----SGTIRVNGQDVSDLRGRAIPYLRRK-IGVVFQD--FRLLPD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 107 MKVGRQI--TEVILQHEKKSKKEAKEIAINLLnDLgiheaEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTA 184
Cdd:cd03292 93 RNVYENVafALEVTGVPPREIRKRVPAALELV-GL-----SHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGN 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446453403 185 LDVTIQKQIMGLLKErKEKQNTSILLITHDLALVREVADRVVVMYGGRI 233
Cdd:cd03292 167 LDPDTTWEIMNLLKK-INKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
5-244 |
8.16e-21 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 89.60 E-value: 8.16e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKqeIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFeskDLTNLQESEW 84
Cdd:cd03251 1 VEFKNVTFRYPGDGPP--VLRDISLDIPAGETVALVGPSGSGKS----TLVNLIPRFYDVDSGRILI---DGHDVRDYTL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRgKDISFIFQDPLSsLNPTmkvgrqITEVILQHEKKSKKEAKEIAINLLNdlgIHEAEKRFEQYPH--------QLS 156
Cdd:cd03251 72 ASLR-RQIGLVSQDVFL-FNDT------VAENIAYGRPGATREEVEEAARAAN---AHEFIMELPEGYDtvigergvKLS 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 157 GGMRQRICLAIAFACHPKLVIADEPTTALDVT----IQKQIMGLLKERkekqnTSIlLITHDLALVREvADRVVVMYGGR 232
Cdd:cd03251 141 GGQRQRIAIARALLKDPPILILDEATSALDTEserlVQAALERLMKNR-----TTF-VIAHRLSTIEN-ADRIVVLEDGK 213
|
250
....*....|..
gi 446453403 233 IVEKGTIQEVIG 244
Cdd:cd03251 214 IVERGTHEELLA 225
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
19-241 |
1.08e-20 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 92.86 E-value: 1.08e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 19 SKQEIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFESKDLTnlqESEWNQIRGKdISFIFQD 98
Cdd:TIGR00958 492 PDVPVLKGLTFTLHPGEVVALVGPSGSGKS----TVAALLQNLYQPTGGQVLLDGVPLV---QYDHHYLHRQ-VALVGQE 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 PLSslnptmkVGRQITEVILQHEKKSKKEAKEIAINLLN-DLGIHEAEKRF--EQYPH--QLSGGMRQRICLAIAFACHP 173
Cdd:TIGR00958 564 PVL-------FSGSVRENIAYGLTDTPDEEIMAAAKAANaHDFIMEFPNGYdtEVGEKgsQLSGGQKQRIAIARALVRKP 636
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 174 KLVIADEPTTALDVTIQKqimgLLKERKEKQNTSILLITHDLALVREvADRVVVMYGGRIVEKGTIQE 241
Cdd:TIGR00958 637 RVLILDEATSALDAECEQ----LLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQ 699
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
25-242 |
1.32e-20 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 92.40 E-value: 1.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 25 KHVSFSINEGEIVALVGESGSGKSvTAQSII-GLnqesIQFDDGNISFESKDLTnlqesewnqIRG-KD-----ISFIFQ 97
Cdd:COG3845 22 DDVSLTVRPGEIHALLGENGAGKS-TLMKILyGL----YQPDSGEILIDGKPVR---------IRSpRDaialgIGMVHQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 DPlsSLNPTMKVgrqiTE-VILQHEKKSKKEakeiainllndLGIHEAEKRF----EQYP---------HQLSGGMRQRI 163
Cdd:COG3845 88 HF--MLVPNLTV----AEnIVLGLEPTKGGR-----------LDRKAARARIrelsERYGldvdpdakvEDLSVGEQQRV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 164 ----CLAiafaCHPKLVIADEPTTALdvTIQ--KQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:COG3845 151 eilkALY----RGARILILDEPTAVL--TPQeaDELFEILRRLAA-EGKSIIFITHKLREVMAIADRVTVLRRGKVVGTV 223
|
....*
gi 446453403 238 TIQEV 242
Cdd:COG3845 224 DTAET 228
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
5-243 |
2.84e-20 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 88.06 E-value: 2.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVekeNSKQEIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGL-------NQESIQFDDGNISfeSKDLT 77
Cdd:cd03253 1 IEFENVTFAY---DPGRPVLKDVSFTIPAGKKVAIVGPSGSGKS----TILRLlfrfydvSSGSILIDGQDIR--EVTLD 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 78 NLQESewnqirgkdISFIFQD-PLssLNPTM----KVGR------QITEVilqhekkskkeaKEIAInllndlgIHEAEK 146
Cdd:cd03253 72 SLRRA---------IGVVPQDtVL--FNDTIgyniRYGRpdatdeEVIEA------------AKAAQ-------IHDKIM 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 147 RF-EQYPHQ-------LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDLALV 218
Cdd:cd03253 122 RFpDGYDTIvgerglkLSGGEKQRVAIARAILKNPPILLLDEATSALDTHTEREIQAAL--RDVSKGRTTIVIAHRLSTI 199
|
250 260
....*....|....*....|....*
gi 446453403 219 REvADRVVVMYGGRIVEKGTIQEVI 243
Cdd:cd03253 200 VN-ADKIIVLKDGRIVERGTHEELL 223
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
22-242 |
3.11e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 88.75 E-value: 3.11e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQES---IQFDDGNISFESKDLTNLQESewnqirgkdISFIFQD 98
Cdd:PRK13636 20 HALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSsgrILFDGKPIDYSRKGLMKLRES---------VGMVFQD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 PLSSLNpTMKVGRQITEVILQHEKKSKKEAKEIAiNLLNDLGIHEAEkrfEQYPHQLSGGMRQRICLAIAFACHPKLVIA 178
Cdd:PRK13636 91 PDNQLF-SASVYQDVSFGAVNLKLPEDEVRKRVD-NALKRTGIEHLK---DKPTHCLSFGQKKRVAIAGVLVMEPKVLVL 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 179 DEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK13636 166 DEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEV 229
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
24-243 |
4.72e-20 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 88.99 E-value: 4.72e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISF-------ESKDLTnlqesewnqirgKDISFIF 96
Cdd:COG4586 38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGI----LVPTSGEVRVlgyvpfkRRKEFA------------RRIGVVF 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 97 -Q------D--PLSSLNpTMKVGRQITEVILQHEkkskkeakeiaINLLND-LGIHEaekrFEQYP-HQLSGGMRQRICL 165
Cdd:COG4586 102 gQrsqlwwDlpAIDSFR-LLKAIYRIPDAEYKKR-----------LDELVElLDLGE----LLDTPvRQLSLGQRMRCEL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 166 AIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:COG4586 166 AAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGSLEELK 243
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
2-233 |
5.23e-20 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 87.81 E-value: 5.23e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 2 GQLLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQE 81
Cdd:PRK11247 10 GTPLLLNAVS----KRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPS----AGELLAGTAPLAEARE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 82 sewnqirgkDISFIFQDplSSLNPTMKVgrqITEVILQHEKKSKKEakeiAINLLNDLGIheaEKRFEQYPHQLSGGMRQ 161
Cdd:PRK11247 82 ---------DTRLMFQD--ARLLPWKKV---IDNVGLGLKGQWRDA----ALQALAAVGL---ADRANEWPAALSGGQKQ 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446453403 162 RICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRI 233
Cdd:PRK11247 141 RVALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
27-234 |
9.39e-20 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 86.47 E-value: 9.39e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEWNQIRgKDISFIFQDPLSSLNPT 106
Cdd:PRK10908 21 VTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPS----AGKIWFSGHDITRLKNREVPFLR-RQIGMIFQDHHLLMDRT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 107 MKVGRQITEVILQHEKKSKKEAKEIAinlLNDLGIHEAEKRFeqyPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALD 186
Cdd:PRK10908 96 VYDNVAIPLIIAGASGDDIRRRVSAA---LDKVGLLDKAKNF---PIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLD 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446453403 187 VTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRIV 234
Cdd:PRK10908 170 DALSEGILRLFEEFN-RVGVTVLMATHDIGLISRRSYRMLTLSDGHLH 216
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
25-246 |
1.08e-19 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 87.38 E-value: 1.08e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 25 KHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTN-LQESEWNQIRgKDISFIFQDPLSSL 103
Cdd:PRK13634 24 YDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGL----LQPTSGTVTIGERVITAgKKNKKLKPLR-KKVGIVFQFPEHQL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 nptmkvgrqITEVILQhekkskkeakEIAINLLNdLGIHEAEKR----------------FEQYPHQLSGGMRQRICLAI 167
Cdd:PRK13634 99 ---------FEETVEK----------DICFGPMN-FGVSEEDAKqkaremielvglpeelLARSPFELSGGQMRRVAIAG 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 168 AFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSP 246
Cdd:PRK13634 159 VLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP 237
|
|
| oligo_HPY |
pfam08352 |
Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found ... |
234-299 |
1.93e-19 |
|
Oligopeptide/dipeptide transporter, C-terminal region; This family features a region found towards the C-terminus of oligopeptide ABC transporter ATP binding proteins, immediately following the ATP-binding domain (pfam00005). All characterized members appear able to be involved in the transport of oligopeptides or dipeptides. Some are important for sporulation or antibiotic resistance. Some dipeptide transporters also act on the heme precursor delta-aminolevulinic acid.
Pssm-ID: 400588 [Multi-domain] Cd Length: 65 Bit Score: 80.91 E-value: 1.93e-19
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 234 VEKGTIQEVIGSPKHPYTKSLLQAIPNMDDAEKVLRAIEGTTPSIETLNSfGCPFVNRCPVAIQEC 299
Cdd:pfam08352 1 VEEGPTDDILENPLHPYTRALLNSVPRLDPPKRPLYTIPGNVPSLLELPE-GCPFAPRCPFATEEC 65
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
8-233 |
2.04e-19 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 85.60 E-value: 2.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 8 ENVTLAVEKENSKQeIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFESKDLTNLQesewNQI 87
Cdd:cd03248 15 QNVTFAYPTRPDTL-VLQDVSFTLHPGEVTALVGPSGSGKS----TVVALLENFYQPQGGQVLLDGKPISQYE----HKY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 88 RGKDISFIFQDPLSSlnptmkvGRQITEVI---LQHEKKSKKEAKEIAINllNDLGIHEAEKRFE----QYPHQLSGGMR 160
Cdd:cd03248 86 LHSKVSLVGQEPVLF-------ARSLQDNIaygLQSCSFECVKEAAQKAH--AHSFISELASGYDtevgEKGSQLSGGQK 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKErkEKQNTSILLITHDLALVrEVADRVVVMYGGRI 233
Cdd:cd03248 157 QRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYD--WPERRTVLVIAHRLSTV-ERADQILVLDGGRI 226
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
4-238 |
2.44e-19 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 88.62 E-value: 2.44e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlaVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFESKDLTNLQ-ES 82
Cdd:TIGR02203 330 DVEFRNVT--FRYPGRDRPALDSISLVIEPGETVALVGRSGSGKS----TLVNLIPRFYEPDSGQILLDGHDLADYTlAS 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNQIR--GKDIsFIFQDPLSSlNPTMKVGRQITEvilqhekkSKKEAKEIAINLLN-----DLGIHEaekRFEQYPHQL 155
Cdd:TIGR02203 404 LRRQVAlvSQDV-VLFNDTIAN-NIAYGRTEQADR--------AEIERALAAAYAQDfvdklPLGLDT---PIGENGVLL 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 156 SGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLkERKEKQNTSiLLITHDLALVrEVADRVVVMYGGRIVE 235
Cdd:TIGR02203 471 SGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAAL-ERLMQGRTT-LVIAHRLSTI-EKADRIVVMDDGRIVE 547
|
...
gi 446453403 236 KGT 238
Cdd:TIGR02203 548 RGT 550
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
27-241 |
2.93e-19 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 88.36 E-value: 2.93e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIG-LNQEsiqfddGNISFESKDLTNLQESEWNQirgkDISFIFQDPL---SS 102
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGfLPYQ------GSLKINGIELRELDPESWRK----HLSWVGQNPQlphGT 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 103 LNPTMKVGR-QITEVILQHekkskkeakeiainLLNDLGIHEAEKRFEQ---YPHQ-----LSGGMRQRICLAIAFACHP 173
Cdd:PRK11174 439 LRDNVLLGNpDASDEQLQQ--------------ALENAWVSEFLPLLPQgldTPIGdqaagLSVGQAQRLALARALLQPC 504
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 174 KLVIADEPTTALDVTIQKQIMGLLKERKEKQNTsiLLITHDLALVREVaDRVVVMYGGRIVEKGTIQE 241
Cdd:PRK11174 505 QLLLLDEPTASLDAHSEQLVMQALNAASRRQTT--LMVTHQLEDLAQW-DQIWVMQDGQIVQQGDYAE 569
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
5-237 |
3.43e-19 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 84.55 E-value: 3.43e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGeIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESew 84
Cdd:cd03264 1 LQLENLT----KRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATL----TPPSSGTIRIDGQDVLKQPQK-- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqIRGKdISFIFQDPlsSLNPTMKVGRQITEVILQHEKKSKKEAKEIaINLLNDLGIHEAEKRfeqYPHQLSGGMRQRIC 164
Cdd:cd03264 70 --LRRR-IGYLPQEF--GVYPNFTVREFLDYIAWLKGIPSKEVKARV-DEVLELVNLGDRAKK---KIGSLSGGMRRRVG 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkqNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03264 141 IAQALVGDPSILIVDEPTAGLDPEERIRFRNLLSELGE--DRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
27-247 |
3.68e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 86.04 E-value: 3.68e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLT-NLQESEWNQIRgKDISFIFQDPLSSLnp 105
Cdd:PRK13641 26 ISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPS----SGTITIAGYHITpETGNKNLKKLR-KKVSLVFQFPEAQL-- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 106 tmkvgrqITEVILQHEK-------KSKKEAKEIAINLLNDLGIheAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIA 178
Cdd:PRK13641 99 -------FENTVLKDVEfgpknfgFSEDEAKEKALKWLKKVGL--SEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 179 DEPTTALDVTIQKQIMGLLKERKEKQNTSIlLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSPK 247
Cdd:PRK13641 170 DEPAAGLDPEGRKEMMQLFKDYQKAGHTVI-LVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKE 237
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
6-262 |
3.87e-19 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 85.13 E-value: 3.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 6 SLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSIIG-LnqesIQFDDGNISFESKDLtnlqeSEW 84
Cdd:COG4604 3 EIKNVS----KRYGGKVVLDDVSLTIPKGGITALIGPNGAGKS-TLLSMISrL----LPPDSGEVLVDGLDV-----ATT 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 -NQIRGKDISFIFQDPlsSLNPTMKV------GR------QITEVILQHEKKskkeakeiAINLLNdlgIHEAEKRfeqY 151
Cdd:COG4604 69 pSRELAKRLAILRQEN--HINSRLTVrelvafGRfpyskgRLTAEDREIIDE--------AIAYLD---LEDLADR---Y 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 152 PHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGG 231
Cdd:COG4604 133 LDELSGGQRQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDG 212
|
250 260 270
....*....|....*....|....*....|.
gi 446453403 232 RIVEKGTIQEVIgspkhpyTKSLLQAIPNMD 262
Cdd:COG4604 213 RVVAQGTPEEII-------TPEVLSDIYDTD 236
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-243 |
4.67e-19 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 84.75 E-value: 4.67e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVT----------------LAVEKENSKQE--IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesI 62
Cdd:COG1134 1 MSSMIEVENVSksyrlyhepsrslkelLLRRRRTRREEfwALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGI----L 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 63 QFDDGNIsfeskdltnlqesewnQIRGKdISFIFqDPLSSLNPTMkVGRQitevilqhekkskkeakEIAIN-LLNDLGI 141
Cdd:COG1134 77 EPTSGRV----------------EVNGR-VSALL-ELGAGFHPEL-TGRE-----------------NIYLNgRLLGLSR 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 142 HEAEKRF---------EQYPHQ----LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSI 208
Cdd:COG1134 121 KEIDEKFdeivefaelGDFIDQpvktYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRE-SGRTV 199
|
250 260 270
....*....|....*....|....*....|....*
gi 446453403 209 LLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:COG1134 200 IFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVI 234
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
4-258 |
5.27e-19 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 87.57 E-value: 5.27e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEkeNSKQEIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFESKDLTNLQESe 83
Cdd:PRK11160 338 SLTLNNVSFTYP--DQPQPVLKGLSLQIKAGEKVALLGRTGCGKS----TLLQLLTRAWDPQQGEILLNGQPIADYSEA- 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnQIRgKDISFIFQ----------DPLSSLNPtmkvgrQITEVILqhekkskkeakeiaINLLNDLGIH---EAEKRFEQ 150
Cdd:PRK11160 411 --ALR-QAISVVSQrvhlfsatlrDNLLLAAP------NASDEAL--------------IEVLQQVGLEkllEDDKGLNA 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 151 Y----PHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDL-ALvrEVADRV 225
Cdd:PRK11160 468 WlgegGRQLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELL--AEHAQNKTVLMITHRLtGL--EQFDRI 543
|
250 260 270
....*....|....*....|....*....|...
gi 446453403 226 VVMYGGRIVEKGTIQEVIGspKHPYTKSLLQAI 258
Cdd:PRK11160 544 CVMDNGQIIEQGTHQELLA--QQGRYYQLKQRL 574
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
5-246 |
5.58e-19 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 86.44 E-value: 5.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEkenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIQfdDGNISFESKDLTNLQESEw 84
Cdd:PRK11650 4 LKLQAVRKSYD---GKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGL--ERIT--SGEIWIGGRVVNELEPAD- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqirgKDISFIFQDplSSLNPTM-------------KVGR-QITEVILQhekkskkeakeiAINLLndlgihEAEKRFEQ 150
Cdd:PRK11650 76 -----RDIAMVFQN--YALYPHMsvrenmayglkirGMPKaEIEERVAE------------AARIL------ELEPLLDR 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 151 YPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQiMGLlkERKEKQ---NTSILLITHDLALVREVADRVVV 227
Cdd:PRK11650 131 KPRELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQ-MRL--EIQRLHrrlKTTSLYVTHDQVEAMTLADRVVV 207
|
250 260 270
....*....|....*....|....*....|.
gi 446453403 228 MYGGRIVEKGTIQEV------------IGSP 246
Cdd:PRK11650 208 MNGGVAEQIGTPVEVyekpastfvasfIGSP 238
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
25-233 |
6.48e-19 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 87.41 E-value: 6.48e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 25 KHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLqeSEWNQIRgKDISFIFQDplssln 104
Cdd:PRK15439 280 RNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPAR----GGRIMLNGKEINAL--STAQRLA-RGLVYLPED------ 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 105 ptmkvgRQITEVILQhekkskkeaKEIAIN----LLNDLGIHEAEKR----FEQYPHQ--------------LSGGMRQR 162
Cdd:PRK15439 347 ------RQSSGLYLD---------APLAWNvcalTHNRRGFWIKPARenavLERYRRAlnikfnhaeqaartLSGGNQQK 411
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKeRKEKQNTSILLITHDLALVREVADRVVVMYGGRI 233
Cdd:PRK15439 412 VLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIR-SIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
5-243 |
9.70e-19 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 86.78 E-value: 9.70e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIQFDDGNISFE------------ 72
Cdd:TIGR03269 1 IEVKNLT----KKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGM--DQYEPTSGRIIYHvalcekcgyver 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 73 -SKDLTNLQESEwNQIRGKDISFIfqdplsslNPTMKVGRQITE---VILQHEKKSKKEAKEI--AINLLNDLGiHEAEK 146
Cdd:TIGR03269 75 pSKVGEPCPVCG-GTLEPEEVDFW--------NLSDKLRRRIRKriaIMLQRTFALYGDDTVLdnVLEALEEIG-YEGKE 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 147 ----------------RFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILL 210
Cdd:TIGR03269 145 avgravdliemvqlshRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVL 224
|
250 260 270
....*....|....*....|....*....|...
gi 446453403 211 ITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:TIGR03269 225 TSHWPEVIEDLSDKAIWLENGEIKEEGTPDEVV 257
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
28-233 |
1.11e-18 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 82.99 E-value: 1.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 28 SFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEwnqirgKDISFIFQDplSSLNPTM 107
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGF----IEPASGSIKVNDQSHTGLAPYQ------RPVSMLFQE--NNLFAHL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 108 KVGRQITEVIlqhekkskkeAKEIAINLLNDLGIHEAEKR------FEQYPHQLSGGMRQRICLAIAFACHPKLVIADEP 181
Cdd:TIGR01277 86 TVRQNIGLGL----------HPGLKLNAEQQEKVVDAAQQvgiadyLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446453403 182 TTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRI 233
Cdd:TIGR01277 156 FSALDPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKI 207
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
4-245 |
3.27e-18 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 82.44 E-value: 3.27e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlaVEKENskQEIVKHVSFSINEGEIVALVGESGSGKS-----VTAQ---------SIIG--LNQESIqFD-D 66
Cdd:COG1119 3 LLELRNVT--VRRGG--KTILDDISWTVKPGEHWAILGPNGAGKStllslITGDlpptygndvRLFGerRGGEDV-WElR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 67 GNISFESKDLTN-LQESEwnqiRGKDISfifqdpLSSLNPTMKVGRQITEVILQHekkskkeakeiAINLLNDLGI-HEA 144
Cdd:COG1119 78 KRIGLVSPALQLrFPRDE----TVLDVV------LSGFFDSIGLYREPTDEQRER-----------ARELLELLGLaHLA 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 145 EKRFeqypHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADR 224
Cdd:COG1119 137 DRPF----GTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITH 212
|
250 260
....*....|....*....|.
gi 446453403 225 VVVMYGGRIVEKGTIQEVIGS 245
Cdd:COG1119 213 VLLLKDGRVVAAGPKEEVLTS 233
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
27-236 |
3.42e-18 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 82.83 E-value: 3.42e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNlqesewnqiRGKDISFIFQD----PLSS 102
Cdd:PRK11248 20 INLTLESGELLVVLGPSGCGKTTLLNLIAGF----VPYQHGSITLDGKPVEG---------PGAERGVVFQNegllPWRN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 103 LNPTMKVGRQITEVilqhekkSKKEAKEIAINLLNDLGIHEAEKRFeqyPHQLSGGMRQRICLAIAFACHPKLVIADEPT 182
Cdd:PRK11248 87 VQDNVAFGLQLAGV-------EKMQRLEIAHQMLKKVGLEGAEKRY---IWQLSGGQRQRVGIARALAANPQLLLLDEPF 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 183 TALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMY--GGRIVEK 236
Cdd:PRK11248 157 GALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSpgPGRVVER 212
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
5-237 |
4.68e-18 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 81.55 E-value: 4.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfdDGNISFESkdLTNLQESEW 84
Cdd:cd03234 4 LPWWDVGLKAKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEG-----GGTTSGQI--LFNGQPRKP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQIRgKDISFIFQDplSSLNPTMKVGRQIT---EVILQHEKKSKKEAKEIAINLLNDLGI-HEAEKRFEQyphqLSGGMR 160
Cdd:cd03234 77 DQFQ-KCVAYVRQD--DILLPGLTVRETLTytaILRLPRKSSDAIRKKRVEDVLLRDLALtRIGGNLVKG----ISGGER 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03234 150 RRVSIAVQLLWDPKVLILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIVYSG 226
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
21-252 |
5.33e-18 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 82.39 E-value: 5.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 21 QEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQ-ESIQFDDGNISFESKDLTNlQESEWNQIRgKDISFIFQDP 99
Cdd:PRK14258 20 QKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNElESEVRVEGRVEFFNQNIYE-RRVNLNRLR-RQVSMVHPKP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 lsSLNPtMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGI-HEAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIA 178
Cdd:PRK14258 98 --NLFP-MSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADLwDEIKHKIHKSALDLSGGQQQRLCIARALAVKPKVLLM 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 179 DEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYG-----GRIVEKGTIQEVIGSPKHPYTK 252
Cdd:PRK14258 175 DEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKKIFNSPHDSRTR 253
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
23-238 |
5.71e-18 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 81.39 E-value: 5.71e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQEsewNQIRGKdISFIFQDPL-- 100
Cdd:cd03244 19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRL----VELSSGSILIDGVDISKIGL---HDLRSR-ISIIPQDPVlf 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 -----SSLNPTmkvGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKrfeqyphQLSGGMRQRICLAIAFACHPKL 175
Cdd:cd03244 91 sgtirSNLDPF---GEYSDEELWQALERVGLKEFVESLPGGLDTVVEEGGE-------NLSVGQRQLLCLARALLRKSKI 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 176 VIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDLALVREvADRVVVMYGGRIVEKGT 238
Cdd:cd03244 161 LVLDEATASVDPETDALIQKTI--REAFKDCTVLTIAHRLDTIID-SDRILVLDKGRVVEFDS 220
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
4-234 |
6.69e-18 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 84.30 E-value: 6.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAvekenskqEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQesiqFDDGNISFESK--DLTNLQE 81
Cdd:COG1129 256 VLEVEGLSVG--------GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADP----ADSGEIRLDGKpvRIRSPRD 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 82 SewnqIRGKdISFIFQDPLSS-LNPTMKVGRQITEVILQHEKKS----KKEAKEIAINLLNDLGIheaekRF---EQYPH 153
Cdd:COG1129 324 A----IRAG-IAYVPEDRKGEgLVLDLSIRENITLASLDRLSRGglldRRRERALAEEYIKRLRI-----KTpspEQPVG 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRI 233
Cdd:COG1129 394 NLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAA-EGKAVIVISSELPELLGLSDRILVMREGRI 472
|
.
gi 446453403 234 V 234
Cdd:COG1129 473 V 473
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
22-238 |
2.54e-17 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 78.99 E-value: 2.54e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSI---IGLNQESIQFDDGNISfeSKDLTNLQESewnqirgkdISFIFQD 98
Cdd:cd03369 22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALfrfLEAEEGKIEIDGIDIS--TIPLEDLRSS---------LTIIPQD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 PL-------SSLNPtmkvgrqitevilqhekkskkeakeiaINLLNDLGIHEAeKRFEQYPHQLSGGMRQRICLAIAFAC 171
Cdd:cd03369 91 PTlfsgtirSNLDP---------------------------FDEYSDEEIYGA-LRVSEGGLNLSQGQRQLLCLARALLK 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 172 HPKLVIADEPTTALDVT----IQKQImgllkeRKEKQNTSILLITHDLalvREVA--DRVVVMYGGRIVEKGT 238
Cdd:cd03369 143 RPRVLVLDEATASIDYAtdalIQKTI------REEFTNSTILTIAHRL---RTIIdyDKILVMDAGEVKEYDH 206
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
22-271 |
3.06e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 80.16 E-value: 3.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEwnqIRGKdISFIFQDPLS 101
Cdd:PRK13647 19 KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQ----RGRVKVMGREVNAENEKW---VRSK-VGLVFQDPDD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 SLnptmkvgrqitevilqhekKSKKEAKEIAINLLN-DLGIHEAEKRFEQY-------------PHQLSGGMRQRICLAI 167
Cdd:PRK13647 91 QV-------------------FSSTVWDDVAFGPVNmGLDKDEVERRVEEAlkavrmwdfrdkpPYHLSYGQKKRVAIAG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 168 AFACHPKLVIADEPTTALDVTIQKQIMGLLkERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTiQEVIGSPK 247
Cdd:PRK13647 152 VLAMDPDVIVLDEPMAYLDPRGQETLMEIL-DRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGD-KSLLTDED 229
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 446453403 248 ----------------HPYTKSLLQAIP-NMDDAEKVLRAI 271
Cdd:PRK13647 230 iveqaglrlplvaqifEDLPELGQSKLPlTVKEAVQIIRKL 270
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
24-246 |
3.32e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 80.42 E-value: 3.32e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNI---SFESKDLTNLQEsewnqIRgKDISFIFQDPl 100
Cdd:PRK13644 18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGL----LRPQKGKVlvsGIDTGDFSKLQG-----IR-KLVGIVFQNP- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 sslnPTMKVGRQITEVILqhEKKSKKEAKEIAINLLNDLGIheAEKRFEQY----PHQLSGGMRQRICLAIAFACHPKLV 176
Cdd:PRK13644 87 ----ETQFVGRTVEEDLA--FGPENLCLPPIEIRKRVDRAL--AEIGLEKYrhrsPKTLSGGQGQCVALAGILTMEPECL 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 177 IADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVrEVADRVVVMYGGRIVEKGTIQEVIGSP 246
Cdd:PRK13644 159 IFDEVTSMLDPDSGIAVLERIKKLHEKGKT-IVYITHNLEEL-HDADRIIVMDRGKIVLEGEPENVLSDV 226
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
7-233 |
9.28e-17 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 80.88 E-value: 9.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 7 LENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFEskdltnlqesewnq 86
Cdd:COG0488 1 LENLSKSF----GGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGE----LEPDSGEVSIP-------------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 87 iRGKDISFIFQDP------------LSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAI-NLLNDLGIHEAEKR------ 147
Cdd:COG0488 59 -KGLRIGYLPQEPpldddltvldtvLDGDAELRALEAELEELEAKLAEPDEDLERLAELqEEFEALGGWEAEARaeeils 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 148 ---FEQYPHQ-----LSGGMRQRICLAIAFACHPKLVIADEPTTALDV-TIQKqimgL---LKERKekqnTSILLITHDL 215
Cdd:COG0488 138 glgFPEEDLDrpvseLSGGWRRRVALARALLSEPDLLLLDEPTNHLDLeSIEW----LeefLKNYP----GTVLVVSHDR 209
|
250
....*....|....*...
gi 446453403 216 ALVREVADRVVVMYGGRI 233
Cdd:COG0488 210 YFLDRVATRILELDRGKL 227
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
22-237 |
1.48e-16 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 77.76 E-value: 1.48e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfddgnisfeSKDLTNLQESEWNQIRG--KDISFIFQD- 98
Cdd:cd03267 35 EALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPT-----------SGEVRVAGLVPWKRRKKflRRIGVVFGQk 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 --------PLSSLNptmkvgrqitevILQHEKKSKKEAKEIAINLLNDLgiHEAEKRFEQYPHQLSGGMRQRICLAIAFA 170
Cdd:cd03267 104 tqlwwdlpVIDSFY------------LLAAIYDLPPARFKKRLDELSEL--LDLEELLDTPVRQLSLGQRMRAEIAAALL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 171 CHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03267 170 HEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
27-256 |
1.68e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 78.62 E-value: 1.68e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGL---NQESIQFDDGNISFESKdltnlqESEWNQIRgKDISFIFQDPLSSL 103
Cdd:PRK13643 25 IDLEVKKGSYTALIGHTGSGKSTLLQHLNGLlqpTEGKVTVGDIVVSSTSK------QKEIKPVR-KKVGVVFQFPESQL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 nptmkvgrqITEVIL-------QHEKKSKKEAKEIAINLLNDLGIheAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLV 176
Cdd:PRK13643 98 ---------FEETVLkdvafgpQNFGIPKEKAEKIAAEKLEMVGL--ADEFWEKSPFELSGGQMRRVAIAGILAMEPEVL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 177 IADEPTTALDVTIQKQIMGLLkERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGT----IQEV-------IGS 245
Cdd:PRK13643 167 VLDEPTAGLDPKARIEMMQLF-ESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTpsdvFQEVdflkaheLGV 245
|
250
....*....|.
gi 446453403 246 PKHPYTKSLLQ 256
Cdd:PRK13643 246 PKATHFADQLQ 256
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
4-243 |
1.92e-16 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 77.31 E-value: 1.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVekenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESE 83
Cdd:PRK10771 1 MLKLTDITWLY------HHLPMRFDLTVERGERVAILGPSGAGKSTLLNLIAGF----LTPASGSLTLNGQDHTTTPPSR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnqirgKDISFIFQDplSSLNPTMKVGRQITEVI---LQHEKKSKKEAKEIAinllNDLGIHEAEKRFeqyPHQLSGGMR 160
Cdd:PRK10771 71 ------RPVSMLFQE--NNLFSHLTVAQNIGLGLnpgLKLNAAQREKLHAIA----RQMGIEDLLARL---PGQLSGGQR 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQ 240
Cdd:PRK10771 136 QRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTD 215
|
...
gi 446453403 241 EVI 243
Cdd:PRK10771 216 ELL 218
|
|
| anch_rpt_ABC |
TIGR03771 |
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ... |
29-242 |
2.37e-16 |
|
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 76.81 E-value: 2.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 29 FSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDltnlQESEWNQIR--GKDISFIFQDPLSSLNPT 106
Cdd:TIGR03771 1 LSADKGELLGLLGPNGAGKTTLLRAILGL----IPPAKGTVKVAGAS----PGKGWRHIGyvPQRHEFAWDFPISVAHTV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 107 MKvGRQITEVILQHEKKSKKEAKEIAinlLNDLGIHEAEKRfeqyP-HQLSGGMRQRICLAIAFACHPKLVIADEPTTAL 185
Cdd:TIGR03771 73 MS-GRTGHIGWLRRPCVADFAAVRDA---LRRVGLTELADR----PvGELSGGQRQRVLVARALATRPSVLLLDEPFTGL 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 186 DVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRvVVMYGGRIVEKGTIQEV 242
Cdd:TIGR03771 145 DMPTQELLTELFIELAGAGTA-ILMTTHDLAQAMATCDR-VVLLNGRVIADGTPQQL 199
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
21-246 |
2.65e-16 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 79.12 E-value: 2.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 21 QEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKDLTNLQESEwnqiRGKDISFIFQDPL 100
Cdd:PRK09536 16 TTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAING----TLTPTAGTVLVAGDDVEALSARA----ASRRVASVPQDTS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 SSLNPTmkvGRQITEV-ILQHEKKSKKEAKEiainllNDLGIHEAEKRFE--QYPHQ----LSGGMRQRICLAIAFACHP 173
Cdd:PRK09536 88 LSFEFD---VRQVVEMgRTPHRSRFDTWTET------DRAAVERAMERTGvaQFADRpvtsLSGGERQRVLLARALAQAT 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 174 KLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLItHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSP 246
Cdd:PRK09536 159 PVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAI-HDLDLAARYCDELVLLADGRVRAAGPPADVLTAD 230
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
27-243 |
2.76e-16 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 78.20 E-value: 2.76e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISF---ESKDLTNLQESEWNQIrgkdiSFIFQDPLSSL 103
Cdd:PRK13651 26 VSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLP----DTGTIEWifkDEKNKKKTKEKEKVLE-----KLVIQKTRFKK 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITEVILQ---HEKKSKKEAKEIAINLLNdLGI--HEAEKRFEQY--------------PHQLSGGMRQRIC 164
Cdd:PRK13651 97 IKKIKEIRRRVGVVFQfaeYQLFEQTIEKDIIFGPVS-MGVskEEAKKRAAKYielvgldesylqrsPFELSGGQKRRVA 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 165 LAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERkEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK13651 176 LAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNL-NKQGKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTYDIL 253
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
22-243 |
4.36e-16 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 79.01 E-value: 4.36e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESEWNQIrgkdISFIFQDPLs 101
Cdd:TIGR01193 488 NILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQAR----SGEILLNGFSLKDIDRHTLRQF----INYLPQEPY- 558
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 slnptMKVGRQITEVILQHEKKSKKEAKEIAINllndlgIHEAEKRFEQYPH-----------QLSGGMRQRICLAIAFA 170
Cdd:TIGR01193 559 -----IFSGSILENLLLGAKENVSQDEIWAACE------IAEIKDDIENMPLgyqtelseegsSISGGQKQRIALARALL 627
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 171 CHPKLVIADEPTTALDVTIQKQIMGLLKERKEKqntSILLITHDLAlVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:TIGR01193 628 TDSKVLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLS-VAKQSDKIIVLDHGKIIEQGSHDELL 696
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
7-242 |
7.11e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 76.59 E-value: 7.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 7 LENVTLAVEKENSKQ-EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGL-NQESIQFDDGNISFESkdltNLQE-SE 83
Cdd:PRK13645 9 LDNVSYTYAKKTPFEfKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLiISETGQTIVGDYAIPA----NLKKiKE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIRgKDISFIFQDPLSSL-NPTMKVGRQITEVILQHEKKSKKEAKEIAINLlndlgIHEAEKRFEQYPHQLSGGMRQR 162
Cdd:PRK13645 85 VKRLR-KEIGLVFQFPEYQLfQETIEKDIAFGPVNLGENKQEAYKKVPELLKL-----VQLPEDYVKRSPFELSGGQKRR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK13645 159 VALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEI 238
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
13-236 |
8.86e-16 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 74.99 E-value: 8.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 13 AVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnQESIQFDDGNIsfeskdltnlqESEWNQIrGKDI 92
Cdd:COG2401 35 GVELRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAG--ALKGTPVAGCV-----------DVPDNQF-GREA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 93 SFIfqDPLSSLNPTmkvgrqitevilqhekkskkeakEIAINLLNDLGIHEAEKRFEQYPHqLSGGMRQRICLAIAFACH 172
Cdd:COG2401 101 SLI--DAIGRKGDF-----------------------KDAVELLNAVGLSDAVLWLRRFKE-LSTGQKFRFRLALLLAER 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 173 PKLVIADEPTTALDVTIQK---QIMGLLKERKEKQntsILLITHDLALVREVADRVVVM--YGGRIVEK 236
Cdd:COG2401 155 PKLLVIDEFCSHLDRQTAKrvaRNLQKLARRAGIT---LVVATHHYDVIDDLQPDLLIFvgYGGVPEEK 220
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
19-246 |
1.00e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 75.99 E-value: 1.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 19 SKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLT--NLQEsewnqIRgKDISFIF 96
Cdd:PRK13652 15 GSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPT----SGSVLIRGEPITkeNIRE-----VR-KFVGLVF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 97 QDPLSSL-NPTMK-------VGRQITEVILQHEKKSKkeakeiainlLNDLGIHEAEKRFeqyPHQLSGGMRQRICLAIA 168
Cdd:PRK13652 85 QNPDDQIfSPTVEqdiafgpINLGLDEETVAHRVSSA----------LHMLGLEELRDRV---PHHLSGGEKKRVAIAGV 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 169 FACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSP 246
Cdd:PRK13652 152 IAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
24-228 |
1.10e-15 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 74.19 E-value: 1.10e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIqfddGNISfeskdltnlqesewnQIRGKDISFIFQdpLSSL 103
Cdd:NF040873 8 LHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTS----GTVR---------------RAGGARVAYVPQ--RSEV 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVG-RQITEVIL-QHEKK---SKKEAKEIAINLLNDLGIHEAEKRfeQYpHQLSGGMRQRICLAIAFACHPKLVIA 178
Cdd:NF040873 67 PDSLPLTvRDLVAMGRwARRGLwrrLTRDDRAAVDDALERVGLADLAGR--QL-GELSGGQRQRALLAQGLAQEADLLLL 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446453403 179 DEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREvADRVVVM 228
Cdd:NF040873 144 DEPTTGLDAESRERIIALLAEEHARGAT-VVVVTHDLELVRR-ADPCVLL 191
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
27-242 |
2.31e-15 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 74.49 E-value: 2.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfddGNISFESKDLTNLQESEWNQIRGkdisFIFQDplSSLNPT 106
Cdd:COG4138 15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGLLPGQ-----GEILLNGRPLSDWSAAELARHRA----YLSQQ--QSPPFA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 107 MKVGRQITeviLQHEKKSKKEAKEIAIN-LLNDLGIheaEKRFEQYPHQLSGGMRQRICLAIAF-----ACHP--KLVIA 178
Cdd:COG4138 84 MPVFQYLA---LHQPAGASSEAVEQLLAqLAEALGL---EDKLSRPLTQLSGGEWQRVRLAAVLlqvwpTINPegQLLLL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 179 DEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:COG4138 158 DEPMNSLDVAQQAALDRLLRELCQQGIT-VVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEV 220
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
5-243 |
3.49e-15 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 76.30 E-value: 3.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSkqeIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEW 84
Cdd:PRK10790 341 IDIDNVSFAYRDDNL---VLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGY----YPLTEGEIRLDGRPLSSLSHSVL 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NQirgkDISFIFQDPL---SSLNPTMKVGRQITEVILQHEKKSKKeakeiainlLNDL------GIHeaeKRFEQYPHQL 155
Cdd:PRK10790 414 RQ----GVAMVQQDPVvlaDTFLANVTLGRDISEEQVWQALETVQ---------LAELarslpdGLY---TPLGEQGNNL 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 156 SGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDLALVREvADRVVVMYGGRIVE 235
Cdd:PRK10790 478 SVGQKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQAL--AAVREHTTLVVIAHRLSTIVE-ADTILVLHRGQAVE 554
|
....*...
gi 446453403 236 KGTIQEVI 243
Cdd:PRK10790 555 QGTHQQLL 562
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
5-233 |
6.03e-15 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 75.35 E-value: 6.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTlAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQfddGNISFESKDLT--NLQES 82
Cdd:PRK13549 260 LEVRNLT-AWDPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPGRWE---GEIFIDGKPVKirNPQQA 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNQI------RGKDisfifqdplsSLNPTMKVGRQITEVILQHEKKSKKeakeiaINLLNDLG-IHEAEKRF------- 148
Cdd:PRK13549 336 IAQGIamvpedRKRD----------GIVPVMGVGKNITLAALDRFTGGSR------IDDAAELKtILESIQRLkvktasp 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 149 EQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVM 228
Cdd:PRK13549 400 ELAIARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLV-QQGVAIIVISSELPEVLGLSDRVLVM 478
|
....*
gi 446453403 229 YGGRI 233
Cdd:PRK13549 479 HEGKL 483
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
21-242 |
6.31e-15 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 73.65 E-value: 6.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 21 QEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKDLTNLQESEWNQIRgKDISFIFQDpl 100
Cdd:PRK11831 20 RCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGG----QIAPDHGEILFDGENIPAMSRSRLYTVR-KRMSMLFQS-- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 SSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFeqyPHQLSGGMRQRICLAIAFACHPKLVIADE 180
Cdd:PRK11831 93 GALFTDMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLM---PSELSGGMARRAALARAIALEPDLIMFDE 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446453403 181 PTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK11831 170 PFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
14-246 |
6.61e-15 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 74.48 E-value: 6.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 14 VEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNIsfeskdlTNLQESEWNQIRG--KD 91
Cdd:PRK13536 47 VSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSP----DAGKI-------TVLGVPVPARARLarAR 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 92 ISFIFQdpLSSLNPTMKVgRQITEVILQHEKKSKKEAKEIAINLLNdlgIHEAEKRFEQYPHQLSGGMRQRICLAIAFAC 171
Cdd:PRK13536 116 IGVVPQ--FDNLDLEFTV-RENLLVFGRYFGMSTREIEAVIPSLLE---FARLESKADARVSDLSGGMKRRLTLARALIN 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 172 HPKLVIADEPTTALDV----TIQKQIMGLLKERKekqntSILLITHDLALVREVADRVVVMYGGRIVEKGT----IQEVI 243
Cdd:PRK13536 190 DPQLLILDEPTTGLDPharhLIWERLRSLLARGK-----TILLTTHFMEEAERLCDRLCVLEAGRKIAEGRphalIDEHI 264
|
...
gi 446453403 244 GSP 246
Cdd:PRK13536 265 GCQ 267
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
16-237 |
9.60e-15 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 72.18 E-value: 9.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 16 KENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISfeskdltnlqesewnqIRGKDISFI 95
Cdd:cd03220 30 GEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGI----YPPDSGTVT----------------VRGRVSSLL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 96 fqDPLSSLNPTMkVGRQitevilqhekkskkeakEIAIN-LLNDLGIHEAEKRF---------EQYPHQ----LSGGMRQ 161
Cdd:cd03220 90 --GLGGGFNPEL-TGRE-----------------NIYLNgRLLGLSRKEIDEKIdeiiefselGDFIDLpvktYSSGMKA 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 162 RICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03220 150 RLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELL-KQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
5-228 |
1.52e-14 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 69.78 E-value: 1.52e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISfeskdltnlqesew 84
Cdd:cd03221 1 IELENLSKTYGG----KLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAG----ELEPDEGIVT-------------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqirgkdisfifqdplssLNPTMKVGrqitevilqhekkskkeakeiainllndlgiheaekrfeqYPHQLSGGMRQRIC 164
Cdd:cd03221 59 ------------------WGSTVKIG----------------------------------------YFEQLSGGEKMRLA 80
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 165 LAIAFACHPKLVIADEPTTALDV-TIQKQIMGLlkerKEKQNTsILLITHDLALVREVADRVVVM 228
Cdd:cd03221 81 LAKLLLENPNLLLLDEPTNHLDLeSIEALEEAL----KEYPGT-VILVSHDRYFLDQVATKIIEL 140
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
5-237 |
1.78e-14 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 71.04 E-value: 1.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKQ--EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnQESIQFDDGNISFESKDLTnlqES 82
Cdd:cd03213 4 LSFRNLTVTVKSSPSKSgkQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAG--RRTGLGVSGEVLINGRPLD---KR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNQIrgkdISFIFQDplSSLNPTMKVgRQitevilqhekkskkeakeiaiNLLndlgiHEAEKRfeqyphQLSGGMRQR 162
Cdd:cd03213 79 SFRKI----IGYVPQD--DILHPTLTV-RE---------------------TLM-----FAAKLR------GLSGGERKR 119
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKeRKEKQNTSILLITHDL-ALVREVADRVVVMYGGRIVEKG 237
Cdd:cd03213 120 VSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLR-RLADTGRTIICSIHQPsSEIFELFDKLLLLSQGRVIYFG 194
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
21-242 |
2.17e-14 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 72.35 E-value: 2.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 21 QEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGL---NQESIQFDDGNISFESKDLTNLQESewnqirgkdISFIFQ 97
Cdd:PRK13638 14 EPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLlrpQKGAVLWQGKPLDYSKRGLLALRQQ---------VATVFQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 DPlsslnptmkvGRQI--TEVilqhekkskkeAKEIAINLLNdLGIHEAE--------------KRFEQYPHQ-LSGGMR 160
Cdd:PRK13638 85 DP----------EQQIfyTDI-----------DSDIAFSLRN-LGVPEAEitrrvdealtlvdaQHFRHQPIQcLSHGQK 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKeRKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQ 240
Cdd:PRK13638 143 KRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIR-RIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPG 221
|
..
gi 446453403 241 EV 242
Cdd:PRK13638 222 EV 223
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
5-243 |
3.41e-14 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 73.13 E-value: 3.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVE-KENSKqeiVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFeskDLTNLQESE 83
Cdd:PRK11176 342 IEFRNVTFTYPgKEVPA---LRNINFKIPAGKTVALVGRSGSGKS----TIANLLTRFYDIDEGEILL---DGHDLRDYT 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnqirgkdisfifqdpLSSLnptmkvgRQITEVILQHekkskkeakeiaINLLNDL----------------GIHEAEKR 147
Cdd:PRK11176 412 ----------------LASL-------RNQVALVSQN------------VHLFNDTianniayarteqysreQIEEAARM 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 148 ------FEQYPH-----------QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERkeKQNTSILL 210
Cdd:PRK11176 457 ayamdfINKMDNgldtvigengvLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDEL--QKNRTSLV 534
|
250 260 270
....*....|....*....|....*....|...
gi 446453403 211 ITHDLALVrEVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK11176 535 IAHRLSTI-EKADEILVVEDGEIVERGTHAELL 566
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
4-242 |
3.55e-14 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 73.28 E-value: 3.55e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQESE 83
Cdd:PRK09700 5 YISMAGIG----KSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPT----KGTITINNINYNKLDHKL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIrgkDISFIFQ-----DPLSSLNpTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHeaeKRFEQYPHQLSGG 158
Cdd:PRK09700 77 AAQL---GIGIIYQelsviDELTVLE-NLYIGRHLTKKVCGVNIIDWREMRVRAAMMLLRVGLK---VDLDEKVANLSIS 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 159 MRQRICLAIAFACHPKLVIADEPTTAL---DVTIQKQIMGLLKerkeKQNTSILLITHDLALVREVADRVVVMYGGRIVE 235
Cdd:PRK09700 150 HKQMLEIAKTLMLDAKVIIMDEPTSSLtnkEVDYLFLIMNQLR----KEGTAIVYISHKLAEIRRICDRYTVMKDGSSVC 225
|
....*..
gi 446453403 236 KGTIQEV 242
Cdd:PRK09700 226 SGMVSDV 232
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
21-243 |
3.59e-14 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 71.08 E-value: 3.59e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 21 QEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEwNQIRGkdISFIFQDP- 99
Cdd:PRK10895 16 RRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGI----VPRDAGNIIIDDEDISLLPLHA-RARRG--IGYLPQEAs 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 ----LSSLNPTMKVgRQITEVILQHEKKSKkeakeiAINLLNDLGIHEAEKRFEQyphQLSGGMRQRICLAIAFACHPKL 175
Cdd:PRK10895 89 ifrrLSVYDNLMAV-LQIRDDLSAEQREDR------ANELMEEFHIEHLRDSMGQ---SLSGGERRRVEIARALAANPKF 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446453403 176 VIADEPTTALD---VTIQKQIMGLLKERkekqNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK10895 159 ILLDEPFAGVDpisVIDIKRIIEHLRDS----GLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEIL 225
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
4-243 |
3.89e-14 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 72.94 E-value: 3.89e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQfddGNISFESK--DLTNLQE 81
Cdd:TIGR02633 257 ILEARNLT-CWDVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKFE---GNVFINGKpvDIRNPAQ 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 82 SewnqIRGKdISFIFQD-PLSSLNPTMKVGRQITEVILQHEKKSKKeakeiaINLLNDLG-IHEAEKRFE---QYPH--- 153
Cdd:TIGR02633 333 A----IRAG-IAMVPEDrKRHGIVPILGVGKNITLSVLKSFCFKMR------IDAAAELQiIGSAIQRLKvktASPFlpi 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 -QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGR 232
Cdd:TIGR02633 402 gRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLA-QEGVAIIVVSSELAEVLGLSDRVLVIGEGK 480
|
250
....*....|....*
gi 446453403 233 I----VEKGTIQEVI 243
Cdd:TIGR02633 481 LkgdfVNHALTQEQV 495
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
36-246 |
4.24e-14 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 72.21 E-value: 4.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 36 IVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEWNQIRGKDISFIFQDplSSLNPTMKVgrqitE 115
Cdd:PRK11144 26 ITAIFGRSGAGKTSLINAISGL----TRPQKGRIVLNGRVLFDAEKGICLPPEKRRIGYVFQD--ARLFPHYKV-----R 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 116 VILQHEKKSKKEAKEIAINLLndLGIheaEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMG 195
Cdd:PRK11144 95 GNLRYGMAKSMVAQFDKIVAL--LGI---EPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLP 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446453403 196 LLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGSP 246
Cdd:PRK11144 170 YLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASS 220
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
24-235 |
4.26e-14 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 72.89 E-value: 4.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTnlQESEWNQIRgKDISFIFQD----- 98
Cdd:PRK09700 279 VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRA----GGEIRLNGKDIS--PRSPLDAVK-KGMAYITESrrdng 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 --PLSSLNPTMKVGRQITEVILQHekkskkeakeiAINLLND---LGIHEAEKR--------FEQYPHQLSGGMRQRICL 165
Cdd:PRK09700 352 ffPNFSIAQNMAISRSLKDGGYKG-----------AMGLFHEvdeQRTAENQREllalkchsVNQNITELSGGNQQKVLI 420
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 166 AIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRIVE 235
Cdd:PRK09700 421 SKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLAD-DGKVILMVSSELPEIITVCDRIAVFCEGRLTQ 489
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
21-215 |
6.31e-14 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 72.39 E-value: 6.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 21 QEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEWNQIrgkdISFIFQDP- 99
Cdd:TIGR02868 348 PPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGL----LDPLQGEVTLDGVPVSSLDQDEVRRR----VSVCAQDAh 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 --LSSLNPTMKVGR------QITEVILqhekkskkeakeiAINLLNDLG---------IHEAEKRfeqyphqLSGGMRQR 162
Cdd:TIGR02868 420 lfDTTVRENLRLARpdatdeELWAALE-------------RVGLADWLRalpdgldtvLGEGGAR-------LSGGERQR 479
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDL 215
Cdd:TIGR02868 480 LALARALLADAPILLLDEPTEHLDAETADELLEDL--LAALSGRTVVLITHHL 530
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
27-242 |
7.19e-14 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 70.35 E-value: 7.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfddGNISFESKDLTNLQESEWNQIRG---KDISFIFQDP---- 99
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLPGS-----GSIQFAGQPLEAWSAAELARHRAylsQQQTPPFAMPvfqy 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 ----LSSLNPTMKVGRQITEVILQhekkskkeakeiaINLLNDLGIHeaekrfeqyPHQLSGGMRQRICLAIAF-----A 170
Cdd:PRK03695 90 ltlhQPDKTRTEAVASALNEVAEA-------------LGLDDKLGRS---------VNQLSGGEWQRVRLAAVVlqvwpD 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 171 CHP--KLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK03695 148 INPagQLLLLDEPMNSLDVAQQAALDRLLSELCQ-QGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEV 220
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
5-238 |
1.09e-13 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 71.77 E-value: 1.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKEnskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGL---NQESIQFDDGNISfeskDLTnlQE 81
Cdd:COG5265 358 VRFENVSFGYDPE---RPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFydvTSGRILIDGQDIR----DVT--QA 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 82 SewnqIRgKDISFIFQDPLssL-NPTMKV----GR------QITEVI-LQHekkskkeakeiainllndlgIHEaekrF- 148
Cdd:COG5265 429 S----LR-AAIGIVPQDTV--LfNDTIAYniayGRpdaseeEVEAAArAAQ--------------------IHD----Fi 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 149 EQYPHQ-----------LSGGMRQRIclAIAFAC--HPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTsiLLITHDL 215
Cdd:COG5265 478 ESLPDGydtrvgerglkLSGGEKQRV--AIARTLlkNPPILIFDEATSALDSRTERAIQAALREVARGRTT--LVIAHRL 553
|
250 260
....*....|....*....|...
gi 446453403 216 ALVREvADRVVVMYGGRIVEKGT 238
Cdd:COG5265 554 STIVD-ADEILVLEAGRIVERGT 575
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
9-247 |
1.87e-13 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 70.44 E-value: 1.87e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 9 NVTLA-VEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqESIQfdDGNISFESKDLTNLQESEwnqi 87
Cdd:PRK11000 3 SVTLRnVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGL--EDIT--SGDLFIGEKRMNDVPPAE---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 88 RGkdISFIFQD----PLSSLNPTMKVG------------RQITEV--ILQhekkskkeakeiainllndLGiHEAEKRfe 149
Cdd:PRK11000 75 RG--VGMVFQSyalyPHLSVAENMSFGlklagakkeeinQRVNQVaeVLQ-------------------LA-HLLDRK-- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 150 qyPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQI-MGLLKERKEKQNTSIlLITHDLALVREVADRVVVM 228
Cdd:PRK11000 131 --PKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMrIEISRLHKRLGRTMI-YVTHDQVEAMTLADKIVVL 207
|
250 260 270
....*....|....*....|....*....|.
gi 446453403 229 YGGRIVEKGTIQEV------------IGSPK 247
Cdd:PRK11000 208 DAGRVAQVGKPLELyhypanrfvagfIGSPK 238
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-226 |
2.96e-13 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 68.60 E-value: 2.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESkdltnlq 80
Cdd:PRK09544 1 MTSLVSLENVSVSF----GQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGL----VAPDEGVIKRNG------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 esewnQIRgkdISFIFQDplSSLNPTM--KVGRQITeviLQHEKKSKkeakeiaiNLLNDLGIHEAEKRFEQYPHQLSGG 158
Cdd:PRK09544 66 -----KLR---IGYVPQK--LYLDTTLplTVNRFLR---LRPGTKKE--------DILPALKRVQAGHLIDAPMQKLSGG 124
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 159 MRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVV 226
Cdd:PRK09544 125 ETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVL 192
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
16-241 |
3.02e-13 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 70.46 E-value: 3.02e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 16 KENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFdDGNIsfeskdLTNLQESEWNQIRgKDISFI 95
Cdd:TIGR00955 33 RERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKG-SGSV------LLNGMPIDAKEMR-AISAYV 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 96 FQDPLssLNPTM------------KVGRQITEVILQHEKKskkeakeiaiNLLNDLGIHEAEKRFEQYPHQ---LSGGMR 160
Cdd:TIGR00955 105 QQDDL--FIPTLtvrehlmfqahlRMPRRVTKKEKRERVD----------EVLQALGLRKCANTRIGVPGRvkgLSGGER 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 161 QRiclaIAFACH----PKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEK 236
Cdd:TIGR00955 173 KR----LAFASElltdPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYL 248
|
....*
gi 446453403 237 GTIQE 241
Cdd:TIGR00955 249 GSPDQ 253
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
7-218 |
3.66e-13 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 67.38 E-value: 3.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 7 LENVTLAVEKenSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQEsewnq 86
Cdd:TIGR01189 1 LAARNLACSR--GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGL----LRPDSGEVRWNGTPLAEQRD----- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 87 IRGKDISFIFQdpLSSLNPTMKVGRQITevILQHEKKSKKEAKEIAINLLNDLGiheaekrFEQYP-HQLSGGMRQRICL 165
Cdd:TIGR01189 70 EPHENILYLGH--LPGLKPELSALENLH--FWAAIHGGAQRTIEDALAAVGLTG-------FEDLPaAQLSAGQQRRLAL 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446453403 166 AIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNtSILLITH-DLALV 218
Cdd:TIGR01189 139 ARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAHLARGG-IVLLTTHqDLGLV 191
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
14-245 |
6.23e-13 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 68.29 E-value: 6.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 14 VEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTnlqeSEWNQIRGKdIS 93
Cdd:PRK13537 13 VEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHP----DAGSISLCGEPVP----SRARHARQR-VG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 94 FIFQdpLSSLNPTMKVgRQITEVILQHEKKSKKEAKEIAINLLNdlgIHEAEKRFEQYPHQLSGGMRQRICLAIAFACHP 173
Cdd:PRK13537 84 VVPQ--FDNLDPDFTV-RENLLVFGRYFGLSAAAARALVPPLLE---FAKLENKADAKVGELSGGMKRRLTLARALVNDP 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 174 KLVIADEPTTALDvtiqKQIMGLLKERKEK---QNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVIGS 245
Cdd:PRK13537 158 DVLVLDEPTTGLD----PQARHLMWERLRSllaRGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIES 228
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
24-252 |
8.83e-13 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 67.50 E-value: 8.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQ--ESIQFDdGNISFESKDLtNLQESEWNQIRgKDISFIFQDPls 101
Cdd:PRK14243 26 VKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDliPGFRVE-GKVTFHGKNL-YAPDVDPVEVR-RRIGMVFQKP-- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 slNPTMKvgrQITEVIL---QHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIA 178
Cdd:PRK14243 101 --NPFPK---SIYDNIAygaRINGYKGDMDELVERSLRQAALWDEVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVILM 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 179 DEPTTALDVTIQKQIMGLLKERKEKQntSILLITHDLALVREVADRV------VVMYGGRI---VEKGTIQEVIGSPKHP 249
Cdd:PRK14243 176 DEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAARVSDMTaffnveLTEGGGRYgylVEFDRTEKIFNSPQQQ 253
|
...
gi 446453403 250 YTK 252
Cdd:PRK14243 254 ATR 256
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
2-234 |
1.04e-12 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 66.13 E-value: 1.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 2 GQLLSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDdGNISFesKDLTNLQE 81
Cdd:cd03233 1 ASTLSWRNISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVSVE-GDIHY--NGIPYKEF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 82 SEWNQirgKDISFIFQDPLSslNPTMKVGRQItevilqhekkskkeakEIAINLLNDlgiheaekrfeQYPHQLSGGMRQ 161
Cdd:cd03233 78 AEKYP---GEIIYVSEEDVH--FPTLTVRETL----------------DFALRCKGN-----------EFVRGISGGERK 125
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 162 RICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLAL-VREVADRVVVMYGGRIV 234
Cdd:cd03233 126 RVSIAEALVSRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASDeIYDLFDKVLVLYEGRQI 199
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
19-246 |
1.35e-12 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 68.20 E-value: 1.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 19 SKQEIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFESKDLTNLQESEWnqiRGK-----DIS 93
Cdd:PRK10789 326 TDHPALENVNFTLKPGQMLGICGPTGSGKS----TLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSW---RSRlavvsQTP 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 94 FIFQDPLSSlnpTMKVGR------QITEVIlqhekkskkeakeiaiNLLNdlgIHEAEKRFEQ-YPHQ-------LSGGM 159
Cdd:PRK10789 399 FLFSDTVAN---NIALGRpdatqqEIEHVA----------------RLAS---VHDDILRLPQgYDTEvgergvmLSGGQ 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 160 RQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQntSILLITHDLALVREvADRVVVMYGGRIVEKGTI 239
Cdd:PRK10789 457 KQRISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQWGEGR--TVIISAHRLSALTE-ASEILVMQHGHIAQRGNH 533
|
....*..
gi 446453403 240 QEVIGSP 246
Cdd:PRK10789 534 DQLAQQS 540
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
5-232 |
1.50e-12 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 65.57 E-value: 1.50e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKQE-IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKdltnlqese 83
Cdd:cd03250 1 ISVEDASFTWDSGEQETSfTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLG----ELEKLSGSVSVPGS--------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 wnqirgkdISFIFQDP-LssLNPTMKvgrqitEVILQHEKKSKKEAKEI--AINLLNDLgiheaekrfEQYPHQ------ 154
Cdd:cd03250 68 --------IAYVSQEPwI--QNGTIR------ENILFGKPFDEERYEKVikACALEPDL---------EILPDGdlteig 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 -----LSGGMRQRICLAIAFACHPKLVIADEPTTALDV-----TIQKQIMGLLKERKekqntSILLITHDLALVREvADR 224
Cdd:cd03250 123 ekginLSGGQKQRISLARAVYSDADIYLLDDPLSAVDAhvgrhIFENCILGLLLNNK-----TRILVTHQLQLLPH-ADQ 196
|
....*...
gi 446453403 225 VVVMYGGR 232
Cdd:cd03250 197 IVVLDNGR 204
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
24-246 |
1.89e-12 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 66.17 E-value: 1.89e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQEsewNQIRGKDISFIFQDplssl 103
Cdd:PRK11300 21 VNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPT----GGTILLRGQHIEGLPG---HQIARMGVVRTFQH----- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 nptMKVGRQITEV----ILQHEKKSKKeakeIAINLLNDLGIHEAEKRFEQYPHQ-----------------LSGGMRQR 162
Cdd:PRK11300 89 ---VRLFREMTVIenllVAQHQQLKTG----LFSGLLKTPAFRRAESEALDRAATwlervgllehanrqagnLAYGQQRR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK11300 162 LEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEI 241
|
....
gi 446453403 243 IGSP 246
Cdd:PRK11300 242 RNNP 245
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
4-226 |
2.25e-12 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 67.67 E-value: 2.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSIigLNQEsIQFDDGNISFEsKDL--TNLQE 81
Cdd:PRK11147 3 LISIHGAWLSF----SDAPLLDNAELHIEDNERVCLVGRNGAGKS-TLMKI--LNGE-VLLDDGRIIYE-QDLivARLQQ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 82 SEWNQIRGKDISFIFQDpLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLG-------IHEAEKRFEQYPHQ 154
Cdd:PRK11147 74 DPPRNVEGTVYDFVAEG-IEEQAEYLKRYHDISHLVETDPSEKNLNELAKLQEQLDHHNlwqlenrINEVLAQLGLDPDA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 155 ----LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKekqnTSILLITHDLALVREVADRVV 226
Cdd:PRK11147 153 alssLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTFQ----GSIIFISHDRSFIRNMATRIV 224
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-234 |
3.68e-12 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 65.29 E-value: 3.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQ 80
Cdd:PRK11614 2 EKVMLSFDKVS----AHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRAT----SGRIVFDGKDITDWQ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 81 ESewnQIRGKDISFIFQdplsslnptmkvGRQI------TEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFeQYPHQ 154
Cdd:PRK11614 74 TA---KIMREAVAIVPE------------GRRVfsrmtvEENLAMGGFFAERDQFQERIKWVYELFPRLHERRI-QRAGT 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRIV 234
Cdd:PRK11614 138 MSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLRE-QGMTIFLVEQNANQALKLADRGYVLENGHVV 216
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
27-243 |
3.74e-12 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 67.28 E-value: 3.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGlNQESIQfddGNISFESKdLTNLQESEWNQIRGKDISFIFQDPLSSlnpt 106
Cdd:TIGR00957 657 ITFSIPEGALVAVVGQVGCGKSSLLSALLA-EMDKVE---GHVHMKGS-VAYVPQQAWIQNDSLRENILFGKALNE---- 727
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 107 mKVGRQITEvilqhekkskkeakeiAINLLNDLGIHEAEKRFE--QYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTA 184
Cdd:TIGR00957 728 -KYYQQVLE----------------ACALLPDLEILPSGDRTEigEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSA 790
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 185 LDVTIQKQI-------MGLLKerkekqNTSILLITHDLALVREVaDRVVVMYGGRIVEKGTIQEVI 243
Cdd:TIGR00957 791 VDAHVGKHIfehvigpEGVLK------NKTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELL 849
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
2-231 |
5.64e-12 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 66.37 E-value: 5.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 2 GQLLSLENVTLAvekENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesiqfddgnisfeskdltnlqe 81
Cdd:COG4178 360 DGALALEDLTLR---TPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGL------------------------ 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 82 seWN----QIR---GKDISFIFQDP---LSSL-------NPTMKVGR-QITEVilqhekkskkeakeiainlLNDLGIHE 143
Cdd:COG4178 413 --WPygsgRIArpaGARVLFLPQRPylpLGTLreallypATAEAFSDaELREA-------------------LEAVGLGH 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 144 AEKRFEQ---YPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDLALvRE 220
Cdd:COG4178 472 LAERLDEeadWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLL--REELPGTTVISVGHRSTL-AA 548
|
250
....*....|.
gi 446453403 221 VADRVVVMYGG 231
Cdd:COG4178 549 FHDRVLELTGD 559
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
3-241 |
6.59e-12 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 66.24 E-value: 6.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 3 QLLSLENVTLAVEKEnskqEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNIsfeskdltnlqes 82
Cdd:COG0488 314 KVLELEGLSKSYGDK----TLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAG----ELEPDSGTV------------- 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 ewnqIRGK--DISFIFQDpLSSLNPTMKVgrqiTEVILQHEKKSKKEAkeiAINLLNDLGIHEAekRFEQYPHQLSGGMR 160
Cdd:COG0488 373 ----KLGEtvKIGYFDQH-QEELDPDKTV----LDELRDGAPGGTEQE---VRGYLGRFLFSGD--DAFKPVGVLSGGEK 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDV-TIQkQIMGLLKERKEkqntSILLITHDLALVREVADRVVVMYGGRIVEK-GT 238
Cdd:COG0488 439 ARLALAKLLLSPPNVLLLDEPTNHLDIeTLE-ALEEALDDFPG----TVLLVSHDRYFLDRVATRILEFEDGGVREYpGG 513
|
...
gi 446453403 239 IQE 241
Cdd:COG0488 514 YDD 516
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
17-298 |
7.38e-12 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 66.58 E-value: 7.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 17 ENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLtnlqESEWNQIRgKDISFIF 96
Cdd:TIGR01257 939 EPSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPT----SGTVLVGGKDI----ETNLDAVR-QSLGMCP 1009
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 97 QDPLSSLNPTmkvgrqITEVILQHEKKSKKEAKEIAINL---LNDLGIHEaeKRFEQyPHQLSGGMRQRICLAIAFACHP 173
Cdd:TIGR01257 1010 QHNILFHHLT------VAEHILFYAQLKGRSWEEAQLEMeamLEDTGLHH--KRNEE-AQDLSGGMQRKLSVAIAFVGDA 1080
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 174 KLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGT---IQEVIGspkhpy 250
Cdd:TIGR01257 1081 KVVVLDEPTSGVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTplfLKNCFG------ 1152
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 446453403 251 TKSLLQAIPNMDDAEKVLRAIEGTTpsieTLNSFGcpFVNRCPVAIQE 298
Cdd:TIGR01257 1153 TGFYLTLVRKMKNIQSQRGGCEGTC----SCTSKG--FSTRCPARVDE 1194
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
24-230 |
2.01e-11 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 63.36 E-value: 2.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFeskdltnLQESEWNQIRGKDISFIFQD----- 98
Cdd:PRK15056 23 LRDASFTVPGGSIAALVGVNGSGKSTLFKALMGF----VRLASGKISI-------LGQPTRQALQKNLVAYVPQSeevdw 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 --PLSSLNPTMkVGRQITEVILQHEKKSKKEAKEIAINLLNDLgiheaEKRFEQYpHQLSGGMRQRICLAIAFACHPKLV 176
Cdd:PRK15056 92 sfPVLVEDVVM-MGRYGHMGWLRRAKKRDRQIVTAALARVDMV-----EFRHRQI-GELSGGQKKRVFLARAIAQQGQVI 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446453403 177 IADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYG 230
Cdd:PRK15056 165 LLDEPFTGVDVKTEARIISLLRELRDEGKT-MLVSTHNLGSVTEFCDYTVMVKG 217
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
6-246 |
2.61e-11 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 62.88 E-value: 2.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 6 SLENVTLAVekenSKQEIVKHVSFSINEGEIVALVGESGSGKSvTAQSIIGLNQESiqfDDGNISFESKDLtnlqeSEWN 85
Cdd:PRK10575 13 ALRNVSFRV----PGRTLLHPLSLTFPAGKVTGLIGHNGSGKS-TLLKMLGRHQPP---SEGEILLDAQPL-----ESWS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 86 -QIRGKDISFIFQDPLSSLNPTMK----VGRQITEVILQHEKKSKKEAKEIAINLLndlGIHEAEKRFEQyphQLSGGMR 160
Cdd:PRK10575 80 sKAFARKVAYLPQQLPAAEGMTVRelvaIGRYPWHGALGRFGAADREKVEEAISLV---GLKPLAHRLVD---SLSGGER 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 161 QRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQ 240
Cdd:PRK10575 154 QRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPA 233
|
....*.
gi 446453403 241 EVIGSP 246
Cdd:PRK10575 234 ELMRGE 239
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
30-230 |
3.91e-11 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 62.43 E-value: 3.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 30 SINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKDLtnlqeSEWNQIRGKDISFIFQDPLSSLNPTMKV 109
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAG----VLKPDEGDIEIELDTV-----SYKPQYIKADYEGTVRDLLSSITKDFYT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 110 GRQ-ITEVIlqhekkskkeakeiainllNDLGIheaEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVT 188
Cdd:cd03237 92 HPYfKTEIA-------------------KPLQI---EQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVE 149
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446453403 189 IQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYG 230
Cdd:cd03237 150 QRLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLIVFEG 191
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
24-233 |
4.63e-11 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 63.48 E-value: 4.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIG-LNQESiqfddGNISFESKDLTNL--QESEWNQI------RGKD--- 91
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGaLPRTS-----GYVTLDGHEVVTRspQDGLANGIvyisedRKRDglv 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 92 --ISFIFQDPLSSLNPTMKVGRQItevilQHEKKSKKEAKEIaiNLLNdlgIHEAEKrfEQYPHQLSGGMRQRICLAIAF 169
Cdd:PRK10762 343 lgMSVKENMSLTALRYFSRAGGSL-----KHADEQQAVSDFI--RLFN---IKTPSM--EQAIGLLSGGNQQKVAIARGL 410
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 170 ACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRI 233
Cdd:PRK10762 411 MTRPKVLILDEPTRGVDVGAKKEIYQLINQFK-AEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
4-237 |
5.54e-11 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 61.73 E-value: 5.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnQESIQFDDGNISFESKDLTNLQESE 83
Cdd:PRK09580 1 MLSIKDLHVSVED----KAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAG--REDYEVTGGTVEFKGKDLLELSPED 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WnqiRGKDISFIFQDPL------------SSLNPTMKVGRQitEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFeqy 151
Cdd:PRK09580 75 R---AGEGIFMAFQYPVeipgvsnqfflqTALNAVRSYRGQ--EPLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGF--- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 152 phqlSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIM-GLLKERKEKQntSILLITHDLALVREVA-DRVVVMY 229
Cdd:PRK09580 147 ----SGGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVAdGVNSLRDGKR--SFIIVTHYQRILDYIKpDYVHVLY 220
|
....*...
gi 446453403 230 GGRIVEKG 237
Cdd:PRK09580 221 QGRIVKSG 228
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
27-235 |
7.29e-11 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 62.88 E-value: 7.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSvTAQSII------GLNQESIQFDDGNISFEskdltNLQESEwnqirGKDISFIFQD-- 98
Cdd:NF040905 20 VNLSVREGEIHALCGENGAGKS-TLMKVLsgvyphGSYEGEILFDGEVCRFK-----DIRDSE-----ALGIVIIHQEla 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 99 --PLSSLNPTMKVGRQITE--VILQHEKKSKkeakeiAINLLNDLGIHEAekrfeqyPHQLSG----GMRQRICLAIAFA 170
Cdd:NF040905 89 liPYLSIAENIFLGNERAKrgVIDWNETNRR------ARELLAKVGLDES-------PDTLVTdigvGKQQLVEIAKALS 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 171 CHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILlITHDLALVREVADRVVVMYGGRIVE 235
Cdd:NF040905 156 KDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSII-ISHKLNEIRRVADSITVLRDGRTIE 219
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-232 |
8.14e-11 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 62.64 E-value: 8.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 1 MGQLLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQfdDGNISFESKDLT--N 78
Cdd:PRK13549 2 MEYLLEMKNIT----KTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGTY--EGEIIFEGEELQasN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 79 LQESEwnqirGKDISFIFQDplSSLNPTMKVGRQI--TEVILQHEKKSKKEAKEIAINLLNDLGIH-EAEKRFEQYphql 155
Cdd:PRK13549 76 IRDTE-----RAGIAIIHQE--LALVKELSVLENIflGNEITPGGIMDYDAMYLRAQKLLAQLKLDiNPATPVGNL---- 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 156 SGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKqNTSILLITHDLALVREVADRVVVMYGGR 232
Cdd:PRK13549 145 GLGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGR 220
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
4-214 |
1.28e-10 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 60.50 E-value: 1.28e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTLAVEKenskQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESE 83
Cdd:PRK10247 7 LLQLQNVGYLAGD----AKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASL----ISPTSGTLLFEGEDISTLKPEI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQirgkDISFIFQDPL---SSLNPTMKVGRQITEvilQHEKKSKkeakeiainLLNDLGIHE-AEKRFEQYPHQLSGGM 159
Cdd:PRK10247 79 YRQ----QVSYCAQTPTlfgDTVYDNLIFPWQIRN---QQPDPAI---------FLDDLERFAlPDTILTKNIAELSGGE 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 160 RQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHD 214
Cdd:PRK10247 143 KQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHD 197
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
155-243 |
1.51e-10 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 60.77 E-value: 1.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIV 234
Cdd:PRK10253 144 LSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIV 223
|
....*....
gi 446453403 235 EKGTIQEVI 243
Cdd:PRK10253 224 AQGAPKEIV 232
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
22-239 |
2.89e-10 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 59.66 E-value: 2.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnQESIQFDDGNISFESKDLTNLQESEWNQiRGkdISFIFQDPLs 101
Cdd:CHL00131 21 EILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPAYKILEGDILFKGESILDLEPEERAH-LG--IFLAFQYPI- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 slnptmkvgrQITEVILQHEKKSKKEAKEIAINL--LNDLG----IHEAEKRFEQYPHQL--------SGGMRQR---IC 164
Cdd:CHL00131 95 ----------EIPGVSNADFLRLAYNSKRKFQGLpeLDPLEfleiINEKLKLVGMDPSFLsrnvnegfSGGEKKRneiLQ 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 165 LAIAfacHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNtSILLITHDLALVREVA-DRVVVMYGGRIVEKGTI 239
Cdd:CHL00131 165 MALL---DSELAILDETDSGLDIDALKIIAEGINKLMTSEN-SIILITHYQRLLDYIKpDYVHVMQNGKIIKTGDA 236
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
7-225 |
3.45e-10 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 58.66 E-value: 3.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 7 LENVTLAVEKEnsKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLtNLQESEWNQ 86
Cdd:cd03231 1 LEADELTCERD--GRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPP----LAGRVLLNGGPL-DFQRDSIAR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 87 irgkDISFIFQDP-----LSSL-NPTMKVGRQITEVILQhekkskkeakeiainLLNDLGIheaeKRFEQYP-HQLSGGM 159
Cdd:cd03231 74 ----GLLYLGHAPgikttLSVLeNLRFWHADHSDEQVEE---------------ALARVGL----NGFEDRPvAQLSAGQ 130
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 160 RQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITH-DLALVREVADRV 225
Cdd:cd03231 131 QRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGHCA-RGGMVVLTTHqDLGLSEAGAREL 196
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
12-251 |
3.89e-10 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 59.54 E-value: 3.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 12 LAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLqesEWNQIRGKd 91
Cdd:cd03288 25 LCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRM----VDIFDGKIVIDGIDISKL---PLHTLRSR- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 92 ISFIFQDPL---SSLNPTMKVGRQITEVILQHEKKSKKEAKEI-AINLLNDLGIHEAEKRFEQyphqlsgGMRQRICLAI 167
Cdd:cd03288 97 LSIILQDPIlfsGSIRFNLDPECKCTDDRLWEALEIAQLKNMVkSLPGGLDAVVTEGGENFSV-------GQRQLFCLAR 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 168 AFACHPKLVIADEPTTALDVT----IQKQIMGLLKERkekqntSILLITHDLALVREvADRVVVMYGGRIVEKGTIQEVI 243
Cdd:cd03288 170 AFVRKSSILIMDEATASIDMAteniLQKVVMTAFADR------TVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENLL 242
|
....*...
gi 446453403 244 GSPKHPYT 251
Cdd:cd03288 243 AQEDGVFA 250
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
24-231 |
4.02e-10 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 58.88 E-value: 4.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKDLTNLQESEWNQIRGKDISFIFQDPLSsL 103
Cdd:cd03290 17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILG----EMQTLEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPWL-L 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKvgrqiTEVILQHEKKSKKEAKEI-AINLLNDLGI--HEAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLVIADE 180
Cdd:cd03290 92 NATVE-----ENITFGSPFNKQRYKAVTdACSLQPDIDLlpFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDD 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446453403 181 PTTALDVTIQKQIM--GLLKERKEKQNTsILLITHDLALVREvADRVVVMYGG 231
Cdd:cd03290 167 PFSALDIHLSDHLMqeGILKFLQDDKRT-LVLVTHKLQYLPH-ADWIIAMKDG 217
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
5-213 |
4.21e-10 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 57.93 E-value: 4.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSkqeIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFEskdltnlqesew 84
Cdd:cd03223 1 IELENLSLATPDGRV---LLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGL----WPWGSGRIGMP------------ 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqiRGKDISFIFQDPLsslnptMKVGRqITEVILqhekkskkeakeiainllndlgiheaekrfeqYP--HQLSGGMRQR 162
Cdd:cd03223 62 ---EGEDLLFLPQRPY------LPLGT-LREQLI--------------------------------YPwdDVLSGGEQQR 99
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446453403 163 ICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKekqnTSILLITH 213
Cdd:cd03223 100 LAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLKELG----ITVISVGH 146
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
22-217 |
4.89e-10 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 58.35 E-value: 4.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEWNQIRGkdisfifqdPLS 101
Cdd:PRK13539 16 VLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGL----LPPAAGTIKLDGGDIDDPDVAEACHYLG---------HRN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 SLNPTMKVgrqitevilqhekkskkeakeiAINLL--------NDLGIHEAEKRFEQYP------HQLSGGMRQRICLAI 167
Cdd:PRK13539 83 AMKPALTV----------------------AENLEfwaaflggEELDIAAALEAVGLAPlahlpfGYLSAGQKRRVALAR 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446453403 168 AFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITH-DLAL 217
Cdd:PRK13539 141 LLVSNRPIWILDEPTAALDAAAVALFAELIRAHLA-QGGIVIAATHiPLGL 190
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
4-241 |
6.31e-10 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 60.06 E-value: 6.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 4 LLSLENVTlaveKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESE 83
Cdd:PRK15439 11 LLCARSIS----KQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGI----VPPDSGTLEIGGNPCARLTPAK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 84 WNQIrgkDISFIFQDPLSSLNPTMKvgrqitEVILQHEKKSKKEAKEIAiNLLNDLGIH----------EAEKRfeQYPH 153
Cdd:PRK15439 83 AHQL---GIYLVPQEPLLFPNLSVK------ENILFGLPKRQASMQKMK-QLLAALGCQldldssagslEVADR--QIVE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 QLSGGMRQriclaiafachPKLVIADEPTTALDV----TIQKQIMGLLKerkekQNTSILLITHDLALVREVADRVVVMY 229
Cdd:PRK15439 151 ILRGLMRD-----------SRILILDEPTASLTPaeteRLFSRIRELLA-----QGVGIVFISHKLPEIRQLADRISVMR 214
|
250
....*....|..
gi 446453403 230 GGRIVEKGTIQE 241
Cdd:PRK15439 215 DGTIALSGKTAD 226
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
23-243 |
1.16e-09 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 59.51 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfddgniSFESKDLTNLQESEwNQIRgKDISFIFQDPLss 102
Cdd:PLN03211 83 ILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGN--------NFTGTILANNRKPT-KQIL-KRTGFVTQDDI-- 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 103 LNPTMKVGRQITEVILQH--EKKSKKEAKEIAINLLNDLGIHEAEKRF--EQYPHQLSGGMRQRICLAIAFACHPKLVIA 178
Cdd:PLN03211 151 LYPHLTVRETLVFCSLLRlpKSLTKQEKILVAESVISELGLTKCENTIigNSFIRGISGGERKRVSIAHEMLINPSLLIL 230
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 179 DEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PLN03211 231 DEPTSGLDATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFGKGSDAM 295
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
27-234 |
1.84e-09 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 58.68 E-value: 1.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQfdDGNISFESKDL--TNLQESEwnqirGKDISFIFQDplSSLN 104
Cdd:TIGR02633 20 IDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTW--DGEIYWSGSPLkaSNIRDTE-----RAGIVIIHQE--LTLV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 105 PTMKVGRQI---TEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKrfEQYPHQLSGGMRQRICLAIAFACHPKLVIADEP 181
Cdd:TIGR02633 91 PELSVAENIflgNEITLPGGRMAYNAMYLRAKNLLRELQLDADNV--TRPVGDYGGGQQQLVEIAKALNKQARLLILDEP 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446453403 182 TTALDVTIQKQIMGLLKERKEKqNTSILLITHDLALVREVADRVVVMYGGRIV 234
Cdd:TIGR02633 169 SSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHV 220
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
26-243 |
2.07e-09 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 58.75 E-value: 2.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 26 HVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFE-SKDLTNLQESEWNQIRGkdisfIFQDPLSSLN 104
Cdd:PRK13545 42 NISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPN----KGTVDIKgSAALIAISSGLNGQLTG-----IENIELKGLM 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 105 PTMKvGRQITEVILQhekkskkeakeiaINLLNDLG--IHEAEKRFeqyphqlSGGMRQRICLAIAFACHPKLVIADEPT 182
Cdd:PRK13545 113 MGLT-KEKIKEIIPE-------------IIEFADIGkfIYQPVKTY-------SSGMKSRLGFAISVHINPDILVIDEAL 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446453403 183 TALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK13545 172 SVGDQTFTKKCLDKMNEFKEQGKT-IFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVV 231
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
23-252 |
2.31e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 58.89 E-value: 2.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGL----NQESIQFDD---GNISFESKD---------LTNLQE-SEWN 85
Cdd:PTZ00265 1183 IYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFydlkNDHHIVFKNehtNDMTNEQDYqgdeeqnvgMKNVNEfSLTK 1262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 86 QIRGKDISFIFQ-------DPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEiAINLLNDLGIHEAEKR----------F 148
Cdd:PTZ00265 1263 EGGSGEDSTVFKnsgkillDGVDICDYNLKDLRNLFSIVSQEPMLFNMSIYE-NIKFGKEDATREDVKRackfaaidefI 1341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 149 EQYPHQ-----------LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLAL 217
Cdd:PTZ00265 1342 ESLPNKydtnvgpygksLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIAS 1421
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 446453403 218 VREvADRVVVM-----YGGRIVEKGTIQEVIGSPKHPYTK 252
Cdd:PTZ00265 1422 IKR-SDKIVVFnnpdrTGSFVQAHGTHEELLSVQDGVYKK 1460
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
27-241 |
3.96e-09 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 56.56 E-value: 3.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGL------NQESIQFDDGNISFESKDLTNLQESEwnqirgKDISFIFQ--- 97
Cdd:PRK09984 23 VDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgdksAGSHIELLGRTVQREGRLARDIRKSR------ANTGYIFQqfn 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 --DPLSSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLLNDLGI-HEAEKRFEQyphqLSGGMRQRICLAIAFACHPK 174
Cdd:PRK09984 97 lvNRLSVLENVLIGALGSTPFWRTCFSWFTREQKQRALQALTRVGMvHFAHQRVST----LSGGQQQRVAIARALMQQAK 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446453403 175 LVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQE 241
Cdd:PRK09984 173 VILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQ 239
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
23-243 |
5.43e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 57.65 E-value: 5.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFeskDLTNLQESEWNQIRGKdISFIFQDPL-- 100
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESA----EGEIII---DGLNIAKIGLHDLRFK-ITIIPQDPVlf 1372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 -SSLNPTMKVGRQITE------VILQHEKKSkkeakeiaINLLNDLGIHEAEKRFEQyphqLSGGMRQRICLAIAFACHP 173
Cdd:TIGR00957 1373 sGSLRMNLDPFSQYSDeevwwaLELAHLKTF--------VSALPDKLDHECAEGGEN----LSVGQRQLVCLARALLRKT 1440
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 174 KLVIADEPTTALDVTIQKQIMGLLkeRKEKQNTSILLITHDLALVREVAdRVVVMYGGRIVEKGTIQEVI 243
Cdd:TIGR00957 1441 KILVLDEATAAVDLETDNLIQSTI--RTQFEDCTVLTIAHRLNTIMDYT-RVIVLDKGEVAEFGAPSNLL 1507
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
22-219 |
6.77e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 57.35 E-value: 6.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 22 EIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFesKDLTNLQESEWNQIRGKdISFIFQDPL- 100
Cdd:PTZ00265 399 EIYKDLNFTLTEGKTYAFVGESGCGKS----TILKLIERLYDPTEGDIII--NDSHNLKDINLKWWRSK-IGVVSQDPLl 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 -------------SSLNPTMKVGRQITE--VILQHEKKSKKEAKEIAINLLNDL-------GIHEAEKRFE--------- 149
Cdd:PTZ00265 472 fsnsiknnikyslYSLKDLEALSNYYNEdgNDSQENKNKRNSCRAKCAGDLNDMsnttdsnELIEMRKNYQtikdsevvd 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 150 ----------------QY-------PHQLSGGMRQRICLAIAFACHPKLVIADEPTTALD----VTIQKQIMGLlkerKE 202
Cdd:PTZ00265 552 vskkvlihdfvsalpdKYetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDnkseYLVQKTINNL----KG 627
|
250
....*....|....*..
gi 446453403 203 KQNTSILLITHDLALVR 219
Cdd:PTZ00265 628 NENRITIIIAHRLSTIR 644
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
5-267 |
8.72e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 56.91 E-value: 8.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKQEIvKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqesiqfddgnisfeskDLTNLQESEW 84
Cdd:PLN03232 615 ISIKNGYFSWDSKTSKPTL-SDINLEIPVGSLVAIVGGTGEGKTSLISAMLG------------------ELSHAETSSV 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 NqIRGK-----DISFIFQDPL-------SSLNPTmKVGRQITEVILQHekkskkeakeiainllnDLGIHEAEKRFE--Q 150
Cdd:PLN03232 676 V-IRGSvayvpQVSWIFNATVrenilfgSDFESE-RYWRAIDVTALQH-----------------DLDLLPGRDLTEigE 736
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 151 YPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIM-GLLKErkEKQNTSILLITHDLALVREVaDRVVVMY 229
Cdd:PLN03232 737 RGVNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFdSCMKD--ELKGKTRVLVTNQLHFLPLM-DRIILVS 813
|
250 260 270
....*....|....*....|....*....|....*...
gi 446453403 230 GGRIVEKGTIQEVigSPKHPYTKSLLQAIPNMDDAEKV 267
Cdd:PLN03232 814 EGMIKEEGTFAEL--SKSGSLFKKLMENAGKMDATQEV 849
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
24-237 |
1.09e-08 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 53.87 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDDgnISFESKDLTnlqesewnqirgkdisfIFQDPLSSL 103
Cdd:cd03238 11 LQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGLYASGKARLISF--LPKFSRNKL-----------------IFIDQLQFL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 nptMKVGrqitevilqhekkskkeakeiaINLLndlgiheaekRFEQYPHQLSGGMRQRICLA--IAFACHPKLVIADEP 181
Cdd:cd03238 72 ---IDVG----------------------LGYL----------TLGQKLSTLSGGELQRVKLAseLFSEPPGTLFILDEP 116
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446453403 182 TTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREvADRVVVM------YGGRIVEKG 237
Cdd:cd03238 117 STGLHQQDINQLLEVIKGLIDLGNT-VILIEHNLDVLSS-ADWIIDFgpgsgkSGGKVVFSG 176
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
155-234 |
1.28e-08 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 56.07 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRIV 234
Cdd:PRK11288 397 LSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAA-QGVAVLFVSSDLPEVLGVADRIVVMREGRIA 475
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
27-243 |
2.07e-08 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 54.44 E-value: 2.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSvTAQSIIGlnqesiqfddGNISFESKDLTnlqesewnqiRGKDISFIFQDplSSLNPT 106
Cdd:PRK13546 43 ISLKAYEGDVIGLVGINGSGKS-TLSNIIG----------GSLSPTVGKVD----------RNGEVSVIAIS--AGLSGQ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 107 MKVGRQIT-EVILQHEKKSKKEAKEIAINLLNDLG--IHEAEKRFeqyphqlSGGMRQRICLAIAFACHPKLVIADEPTT 183
Cdd:PRK13546 100 LTGIENIEfKMLCMGFKRKEIKAMTPKIIEFSELGefIYQPVKKY-------SSGMRAKLGFSINITVNPDILVIDEALS 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 184 ALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PRK13546 173 VGDQTFAQKCLDKIYEFKE-QNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVL 231
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
155-248 |
4.06e-08 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 53.68 E-value: 4.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAFA---------CHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRV 225
Cdd:PRK13547 146 LSGGELARVQFARVLAqlwpphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRI 225
|
90 100
....*....|....*....|...
gi 446453403 226 VVMYGGRIVEKGTIQEVIgSPKH 248
Cdd:PRK13547 226 AMLADGAIVAHGAPADVL-TPAH 247
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
23-243 |
4.45e-08 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 54.74 E-value: 4.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQS---IIGLNQESIQFDDGNISfeSKDLTNLQesewnqirgKDISFIFQDP 99
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNAlfrIVELERGRILIDGCDIS--KFGLMDLR---------KVLGIIPQAP 1322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 -LSS------LNPTmkvgRQITEVILQHEKKSKKEAKEIAINLLN-DLGIHEAEKRFeqyphqlSGGMRQRICLAIAFAC 171
Cdd:PLN03130 1323 vLFSgtvrfnLDPF----NEHNDADLWESLERAHLKDVIRRNSLGlDAEVSEAGENF-------SVGQRQLLSLARALLR 1391
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 172 HPKLVIADEPTTALDV----TIQKQImgllkeRKEKQNTSILLITHDLALVREvADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PLN03130 1392 RSKILVLDEATAAVDVrtdaLIQKTI------REEFKSCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLL 1460
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
34-228 |
6.60e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 51.22 E-value: 6.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 34 GEIVALVGESGSGKSVTAQSIIGlnqesiQFDDGNISFESKDLTNLQESEWNQIRGKDIsfifqdplsslnptmkvgrqi 113
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALAR------ELGPPGGGVIYIDGEDILEEVLDQLLLIIV--------------------- 54
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 114 tevilqhekkskkeakeiainllndlgiheaekrfEQYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQI 193
Cdd:smart00382 55 -----------------------------------GGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALL 99
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446453403 194 M-----GLLKERKEKQNTSILLITHDL-----ALVREVADRVVVM 228
Cdd:smart00382 100 LlleelRLLLLLKSEKNLTVILTTNDEkdlgpALLRRRFDRRIVL 144
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
30-230 |
8.85e-08 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 53.63 E-value: 8.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 30 SINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKdltnlqesewnqIRGK------DISFIFQDPLSSL 103
Cdd:COG1245 362 EIREGEVLGIVGPNGIGKTTFAKILAGV----LKPDEGEVDEDLK------------ISYKpqyispDYDGTVEEFLRSA 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMkvgrqITEVILQHekkskkeakeiaiNLLNDLGIHeaeKRFEQYPHQLSGGMRQRicLAIAfACHPK---LVIADE 180
Cdd:COG1245 426 NTDD-----FGSSYYKT-------------EIIKPLGLE---KLLDKNVKDLSGGELQR--VAIA-ACLSRdadLYLLDE 481
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446453403 181 PTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYG 230
Cdd:COG1245 482 PSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHDIYLIDYISDRLMVFEG 531
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
155-243 |
1.09e-07 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 53.48 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAF---ACHPKLVIADEPTTAL---DVtiqKQIMGLLKERKEKQNTsILLITHDLALVReVADRVVVM 228
Cdd:TIGR00630 830 LSGGEAQRIKLAKELskrSTGRTLYILDEPTTGLhfdDI---KKLLEVLQRLVDKGNT-VVVIEHNLDVIK-TADYIIDL 904
|
90 100
....*....|....*....|.
gi 446453403 229 ------YGGRIVEKGTIQEVI 243
Cdd:TIGR00630 905 gpeggdGGGTVVASGTPEEVA 925
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
28-236 |
1.19e-07 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 53.08 E-value: 1.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 28 SFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDlTNLQESEWNQIRGkdISFIFQD----PLSSL 103
Cdd:PRK10762 24 ALNVYPGRVMALVGENGAGKSTMMKVLTGIYTR----DAGSILYLGKE-VTFNGPKSSQEAG--IGIIHQElnliPQLTI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITEVI--LQHEKKSKKeakeiAINLLNDLGIHEAEKRFEQyphQLSGGMRQRICLAIAFACHPKLVIADEP 181
Cdd:PRK10762 97 AENIFLGREFVNRFgrIDWKKMYAE-----ADKLLARLNLRFSSDKLVG---ELSIGEQQMVEIAKVLSFESKVIIMDEP 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 182 TTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGR-IVEK 236
Cdd:PRK10762 169 TDALTDTETESLFRVIRELKS-QGRGIVYISHRLKEIFEICDDVTVFRDGQfIAER 223
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
155-230 |
1.27e-07 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 51.03 E-value: 1.27e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446453403 155 LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLALVREVADRVVVMYG 230
Cdd:cd03222 72 LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHVFEG 147
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
28-242 |
1.30e-07 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 52.71 E-value: 1.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 28 SFSINEGEIVALVGESGSGKSVTAQSIIG-LNQES----IQFDDG-NISFESkdLTNLQESEWnQIRGKDISFIFQDpls 101
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGeLPLLSgerqSQFSHItRLSFEQ--LQKLVSDEW-QRNNTDMLSPGED--- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 slnptmKVGRQITEVILQHEKKSKKEAKEIAInllndLGI-HEAEKRFEQyphqLSGGMRQRICLAIAFACHPKLVIADE 180
Cdd:PRK10938 97 ------DTGRTTAEIIQDEVKDPARCEQLAQQ-----FGItALLDRRFKY----LSTGETRKTLLCQALMSEPDLLILDE 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446453403 181 PTTALDVTIQKQIMGLLkERKEKQNTSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:PRK10938 162 PFDGLDVASRQQLAELL-ASLHQSGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEI 222
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
154-230 |
2.53e-07 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 52.09 E-value: 2.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 QLSGGMRQRICLAIAFACHPKLVIADEPTTALDV----TIQKQIMGLLKERKekqntSILLITHDLALVREVADRVVVMY 229
Cdd:COG1245 212 ELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIyqrlNVARLIRELAEEGK-----YVLVVEHDLAILDYLADYVHILY 286
|
.
gi 446453403 230 G 230
Cdd:COG1245 287 G 287
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
3-235 |
2.58e-07 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 51.90 E-value: 2.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 3 QLLSLENVTLAVEKENSKqeiVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKDLTNLQES 82
Cdd:PRK10522 321 QTLELRNVTFAYQDNGFS---VGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQ----SGEILLDGKPVTAEQPE 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 83 EWNQIrgkdISFIFQD--PLSSLnptmkVGRQITEVilqhekkskkeAKEIAINLLNDLG----IHEAEKRFEQYphQLS 156
Cdd:PRK10522 394 DYRKL----FSAVFTDfhLFDQL-----LGPEGKPA-----------NPALVEKWLERLKmahkLELEDGRISNL--KLS 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 157 GGMRQRICLAIAFACHPKLVIADEPTTALDVTIQK----QIMGLLKErkekQNTSILLITHDLALVrEVADRVVVMYGGR 232
Cdd:PRK10522 452 KGQKKRLALLLALAEERDILLLDEWAADQDPHFRRefyqVLLPLLQE----MGKTIFAISHDDHYF-IHADRLLEMRNGQ 526
|
...
gi 446453403 233 IVE 235
Cdd:PRK10522 527 LSE 529
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
31-230 |
3.94e-07 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 51.35 E-value: 3.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 31 INEGEIVALVGESGSGKSVTAQSIIGlnqeSIQFDDGNISFESKdltnlqesewnqirgkdISF----IFQDPlsslnpT 106
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAG----VLKPDEGEVDPELK-----------------ISYkpqyIKPDY------D 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 107 MKVG---RQITEVIlqhekkskkEAKEIAINLLNDLGIheaEKRFEQYPHQLSGGMRQRicLAIAfACHPK---LVIADE 180
Cdd:PRK13409 415 GTVEdllRSITDDL---------GSSYYKSEIIKPLQL---ERLLDKNVKDLSGGELQR--VAIA-ACLSRdadLYLLDE 479
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 181 PTTALDV--------TIQKQImgllkerkEKQNTSILLITHDLALVREVADRVVVMYG 230
Cdd:PRK13409 480 PSAHLDVeqrlavakAIRRIA--------EEREATALVVDHDIYMIDYISDRLMVFEG 529
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
5-263 |
4.92e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 51.66 E-value: 4.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 5 LSLENVTLAVEKENSKQEIvKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnqESIQFDDGNISfeskdltnlqesew 84
Cdd:PLN03130 615 ISIKNGYFSWDSKAERPTL-SNINLDVPVGSLVAIVGSTGEGKTSLISAMLG---ELPPRSDASVV-------------- 676
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 85 nqIRGK-----DISFIFQDPL-------SSLNPTmKVGRQITEVILQHEkkskkeakeiaINLLNDLGIHEAEKRfeqyP 152
Cdd:PLN03130 677 --IRGTvayvpQVSWIFNATVrdnilfgSPFDPE-RYERAIDVTALQHD-----------LDLLPGGDLTEIGER----G 738
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 153 HQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMG-LLKErkEKQNTSILLITHDLALVREVaDRVVVMYGG 231
Cdd:PLN03130 739 VNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFDkCIKD--ELRGKTRVLVTNQLHFLSQV-DRIILVHEG 815
|
250 260 270
....*....|....*....|....*....|..
gi 446453403 232 RIVEKGTIQEVIGSpkHPYTKSLLQAIPNMDD 263
Cdd:PLN03130 816 MIKEEGTYEELSNN--GPLFQKLMENAGKMEE 845
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
33-230 |
5.28e-07 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 50.06 E-value: 5.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 33 EGEIVALVGESGSGKSvTAQSIIGlnqesiqfddgnisfeSKDLTNL----QESEWNQI----RGKDISFIFQDPLS-SL 103
Cdd:cd03236 25 EGQVLGLVGPNGIGKS-TALKILA----------------GKLKPNLgkfdDPPDWDEIldefRGSELQNYFTKLLEgDV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVgrqitevilQHEKKSKKEAKEIAINLLN---DLGIH-------EAEKRFEQYPHQLSGGMRQRICLAIAFACHP 173
Cdd:cd03236 88 KVIVKP---------QYVDLIPKAVKGKVGELLKkkdERGKLdelvdqlELRHVLDRNIDQLSGGELQRVAIAAALARDA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446453403 174 KLVIADEPTTALDV----TIQKQIMGLLKERKekqntSILLITHDLALVREVADRVVVMYG 230
Cdd:cd03236 159 DFYFFDEPSSYLDIkqrlNAARLIRELAEDDN-----YVLVVEHDLAVLDYLSDYIHCLYG 214
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
154-230 |
1.07e-06 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 50.19 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 QLSGGMRQRicLAIAfACHPK---LVIADEPTTALDVtiqKQIMGLLKE-RKEKQNTSILLITHDLALVREVADRVVVMY 229
Cdd:PRK13409 212 ELSGGELQR--VAIA-AALLRdadFYFFDEPTSYLDI---RQRLNVARLiRELAEGKYVLVVEHDLAVLDYLADNVHIAY 285
|
.
gi 446453403 230 G 230
Cdd:PRK13409 286 G 286
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
30-226 |
1.24e-06 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 50.17 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 30 SINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNISFESkdltNLQESEWNQ-------------IRGKDISFIF 96
Cdd:PRK10636 23 TINPGQKVGLVGKNGCGKS----TLLALLKNEISADGGSYTFPG----NWQLAWVNQetpalpqpaleyvIDGDREYRQL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 97 QDPLSSLNPTMKvGRQITEVILQHEKKSKKEAKEIAINLLNDLGIheAEKRFEQYPHQLSGGMRQRICLAIAFACHPKLV 176
Cdd:PRK10636 95 EAQLHDANERND-GHAIATIHGKLDAIDAWTIRSRAASLLHGLGF--SNEQLERPVSDFSGGWRMRLNLAQALICRSDLL 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446453403 177 IADEPTTALDVtiqKQIMGLLKERKEKQNTSIlLITHDLALVREVADRVV 226
Cdd:PRK10636 172 LLDEPTNHLDL---DAVIWLEKWLKSYQGTLI-LISHDRDFLDPIVDKII 217
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
24-242 |
1.51e-06 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 50.01 E-value: 1.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAQSIIGlnQESIQFDDGNISFESKdLTNLqeSEWNQIRGKDISFIFQDPLSSl 103
Cdd:TIGR01257 1955 VDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTG--DTTVTSGDATVAGKSI-LTNI--SDVHQNMGYCPQFDAIDDLLT- 2028
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 nptmkvGRQITEVILQHEKKSKKEAKEIAINLLNDLGIHEAEKRFEQyphQLSGGMRQRICLAIAFACHPKLVIADEPTT 183
Cdd:TIGR01257 2029 ------GREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAG---TYSGGNKRKLSTAIALIGCPPLVLLDEPTT 2099
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446453403 184 ALDVTIQKQ----IMGLLKERKekqntSILLITHDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:TIGR01257 2100 GMDPQARRMlwntIVSIIREGR-----AVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHL 2157
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
132-242 |
1.65e-06 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 49.35 E-value: 1.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 132 AINLLNDLGIHEAEKRFEQyphQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLI 211
Cdd:NF000106 125 ADELLERFSLTEAAGRAAA---KYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMV-RDGATVLLT 200
|
90 100 110
....*....|....*....|....*....|.
gi 446453403 212 THDLALVREVADRVVVMYGGRIVEKGTIQEV 242
Cdd:NF000106 201 TQYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
25-237 |
1.80e-06 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 48.02 E-value: 1.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 25 KHVSFSINEGEIVALVGESGSGKSVTA-QSIIGLNQ----ESIQfddgniSFESKDLTNLQESEWNQIRGKDISFIFQDP 99
Cdd:cd03270 12 KNVDVDIPRNKLVVITGVSGSGKSSLAfDTIYAEGQrryvESLS------AYARQFLGQMDKPDVDSIEGLSPAIAIDQK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 100 LSSLNPTMKVGrQITEvILQHEKKSKKEAKEIA-INLLNDLGIHEAekRFEQYPHQLSGGMRQRICLAIAFAChpKLV-- 176
Cdd:cd03270 86 TTSRNPRSTVG-TVTE-IYDYLRLLFARVGIRErLGFLVDVGLGYL--TLSRSAPTLSGGEAQRIRLATQIGS--GLTgv 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 177 --IADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREvADRVVVM------YGGRIVEKG 237
Cdd:cd03270 160 lyVLDEPSIGLHPRDNDRLIETLKRLRDLGNT-VLVVEHDEDTIRA-ADHVIDIgpgagvHGGEIVAQG 226
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
153-229 |
2.02e-06 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 46.97 E-value: 2.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 153 HQLSGGMRQRICLAIAFACHPK----LVIADEPTTALDVTIQKQIMGLLKERKEKQNTSIlLITHDLALVrEVADRVVVM 228
Cdd:cd03227 76 LQLSGGEKELSALALILALASLkprpLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVI-VITHLPELA-ELADKLIHI 153
|
.
gi 446453403 229 Y 229
Cdd:cd03227 154 K 154
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
27-243 |
2.34e-06 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 49.59 E-value: 2.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 27 VSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesIQFDDGNISFESKDLTNLQESEWNQIrgkdISFIFQDPLSsLNPT 106
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRI----VELEKGRIMIDDCDVAKFGLTDLRRV----LSIIPQSPVL-FSGT 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 107 MKVGrqiTEVILQHekkskkeakeiainllNDLGIHEAEKR------FEQYPHQL-----------SGGMRQRICLAIAF 169
Cdd:PLN03232 1326 VRFN---IDPFSEH----------------NDADLWEALERahikdvIDRNPFGLdaevseggenfSVGQRQLLSLARAL 1386
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 170 ACHPKLVIADEPTTALDVTIQKQIMGLLKErkEKQNTSILLITHDLALVREvADRVVVMYGGRIVEKGTIQEVI 243
Cdd:PLN03232 1387 LRRSKILVLDEATASVDVRTDSLIQRTIRE--EFKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELL 1457
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
7-218 |
2.87e-06 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 48.79 E-value: 2.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 7 LENVTLAVEKENskqeIVKHVSFSINEGEIVALVGESGSGKSvtaqSIIGLNQESIQFDDGNIsfesKDLTNLQESEWNQ 86
Cdd:PRK11147 322 MENVNYQIDGKQ----LVKDFSAQVQRGDKIALIGPNGCGKT----TLLKLMLGQLQADSGRI----HCGTKLEVAYFDQ 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 87 IRgkdisfifqdplSSLNPTMKV------GRQITEV--ILQHekkskkeakeiAINLLNDLGIHEaeKRFEQYPHQLSGG 158
Cdd:PRK11147 390 HR------------AELDPEKTVmdnlaeGKQEVMVngRPRH-----------VLGYLQDFLFHP--KRAMTPVKALSGG 444
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 159 MRQRICLAIAFACHPKLVIADEPTTALDVtiqkQIMGLLKERKEKQNTSILLITHDLALV 218
Cdd:PRK11147 445 ERNRLLLARLFLKPSNLLILDEPTNDLDV----ETLELLEELLDSYQGTVLLVSHDRQFV 500
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
26-217 |
3.87e-06 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 47.11 E-value: 3.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 26 HVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfDDGNISFESKDLTNLQEsEWNQirgkDISFI---------- 95
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARP----DAGEVLWQGEPIRRQRD-EYHQ----DLLYLghqpgiktel 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 96 -------FQDPLSSLnptmkVGRQITEVILQhekkskkeakeiAINLlndlgiheaeKRFEQYP-HQLSGGMRQRICLAI 167
Cdd:PRK13538 90 talenlrFYQRLHGP-----GDDEALWEALA------------QVGL----------AGFEDVPvRQLSAGQQRRVALAR 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446453403 168 AFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHDLAL 217
Cdd:PRK13538 143 LWLTRAPLWILDEPFTAIDKQGVARLEALLAQHAEQGGMVILTTHQDLPV 192
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
155-238 |
4.06e-06 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 47.61 E-value: 4.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAF---ACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVReVADRVVVM--- 228
Cdd:cd03271 170 LSGGEAQRIKLAKELskrSTGKTLYILDEPTTGLHFHDVKKLLEVLQRLVDKGNT-VVVIEHNLDVIK-CADWIIDLgpe 247
|
90
....*....|...
gi 446453403 229 ---YGGRIVEKGT 238
Cdd:cd03271 248 ggdGGGQVVASGT 260
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
23-262 |
4.75e-06 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 47.54 E-value: 4.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLnqesiQFDDGNISFESKDLTNLQESEWNQIRG--KDISFIFQDPL 100
Cdd:cd03289 19 VLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRL-----LNTEGDIQIDGVSWNSVPLQKWRKAFGviPQKVFIFSGTF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 -SSLNPTmkvGRQITEVILQhekkskkeakeiainLLNDLGIHEAekrFEQYPHQ-----------LSGGMRQRICLAIA 168
Cdd:cd03289 94 rKNLDPY---GKWSDEEIWK---------------VAEEVGLKSV---IEQFPGQldfvlvdggcvLSHGHKQLMCLARS 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 169 FACHPKLVIADEPTTALDVTIQKQIMGLLKErkEKQNTSILLITHDLALVREvADRVVVMYGGRIVEKGTIQEVIGSpkh 248
Cdd:cd03289 153 VLSKAKILLLDEPSAHLDPITYQVIRKTLKQ--AFADCTVILSEHRIEAMLE-CQRFLVIEENKVRQYDSIQKLLNE--- 226
|
250
....*....|....
gi 446453403 249 pyTKSLLQAIPNMD 262
Cdd:cd03289 227 --KSHFKQAISPSD 238
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
139-229 |
4.77e-06 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 47.62 E-value: 4.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 139 LGIHEAEKRFEQYPHQLSGGMRQRICLAIAFAC--HPKLVIADEPTTALDVTIQKQIMGLLKER-KEKQntsILLITHDL 215
Cdd:COG4637 243 LEFREKGLDRPFPARELSDGTLRFLALLAALLSprPPPLLCIEEPENGLHPDLLPALAELLREAsERTQ---VIVTTHSP 319
|
90
....*....|....*
gi 446453403 216 ALVREVA-DRVVVMY 229
Cdd:COG4637 320 ALLDALEpEEVLVLE 334
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
155-247 |
5.05e-06 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 48.09 E-value: 5.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLA--IAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTsILLITHDLALVREvADRVVVM---- 228
Cdd:TIGR00630 489 LSGGEAQRIRLAtqIGSGLTGVLYVLDEPSIGLHQRDNRRLINTLKRLRDLGNT-LIVVEHDEDTIRA-ADYVIDIgpga 566
|
90 100
....*....|....*....|.
gi 446453403 229 --YGGRIVEKGTIQEVIGSPK 247
Cdd:TIGR00630 567 geHGGEVVASGTPEEILANPD 587
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
23-305 |
1.08e-05 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 47.21 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESiqfdDGNISFESKdltnlqesewnqirgkdISFIFQDPL-- 100
Cdd:TIGR01271 441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPS----EGKIKHSGR-----------------ISFSPQTSWim 499
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 -SSLNPTMKVGRQITEVILQHEKKSKKEAKEIAI------NLLNDLGIheaekrfeqyphQLSGGMRQRICLAIAFACHP 173
Cdd:TIGR01271 500 pGTIKDNIIFGLSYDEYRYTSVIKACQLEEDIALfpekdkTVLGEGGI------------TLSGGQRARISLARAVYKDA 567
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 174 KLVIADEPTTALDVTIQKQIMgllkER---KEKQNTSILLITHDLALVREvADRVVVMYGGRIVEKGTIQEVIGspKHPY 250
Cdd:TIGR01271 568 DLYLLDSPFTHLDVVTEKEIF----ESclcKLMSNKTRILVTSKLEHLKK-ADKILLLHEGVCYFYGTFSELQA--KRPD 640
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 251 TKSLLQAIPNMDDAekvlraiegttpSIETLNSFGCPFVNRCPVAIQECIHRFPE 305
Cdd:TIGR01271 641 FSSLLLGLEAFDNF------------SAERRNSILTETLRRVSIDGDSTVFSGPE 683
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
15-336 |
1.35e-05 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 47.03 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 15 EKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQESIQFDDGNISFESKDLTNLQesewNQIRGK---- 90
Cdd:TIGR00956 68 FRDTKTFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDGFHIGVEGVITYDGITPEEIK----KHYRGDvvyn 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 91 ---DISF---IFQDPL-------SSLNPTMKVGRQ-----ITEVI-----LQHEKKSkkeakeiaiNLLNDL--GIheae 145
Cdd:TIGR00956 144 aetDVHFphlTVGETLdfaarckTPQNRPDGVSREeyakhIADVYmatygLSHTRNT---------KVGNDFvrGV---- 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 146 krfeqyphqlSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKErkekqntsILLITHDLALVR------ 219
Cdd:TIGR00956 211 ----------SGGERKRVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKT--------SANILDTTPLVAiyqcsq 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 220 ---EVADRVVVMYGGRIVEKGTIQEV------IG--SPKHPYTKSLLQAIpnmddaekvlraiegTTPSIETLNSfgcPF 288
Cdd:TIGR00956 273 dayELFDKVIVLYEGYQIYFGPADKAkqyfekMGfkCPDRQTTADFLTSL---------------TSPAERQIKP---GY 334
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 446453403 289 VNRCPVAIQECI---HRFPERTTYSAEHSshcwQHVLEHDRAKSKEKVNAS 336
Cdd:TIGR00956 335 EKKVPRTPQEFEtywRNSPEYAQLMKEID----EYLDRCSESDTKEAYRES 381
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
154-242 |
1.44e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 46.66 E-value: 1.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 154 QLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKE-RKEKQNTSILLIThdlALVREVA--DRVVVMYG 230
Cdd:NF033858 136 KLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRiRAERPGMSVLVAT---AYMEEAErfDWLVAMDA 212
|
90
....*....|..
gi 446453403 231 GRIVEKGTIQEV 242
Cdd:NF033858 213 GRVLATGTPAEL 224
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
26-235 |
3.00e-05 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 45.67 E-value: 3.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 26 HVSFSINEGEIVALVGESGSGKSvTAQSIIGLNQesiQFDDGNISFESKDL--TNLQESewnqiRGKDISFIFQDplSSL 103
Cdd:PRK11288 22 DISFDCRAGQVHALMGENGAGKS-TLLKILSGNY---QPDAGSILIDGQEMrfASTTAA-----LAAGVAIIYQE--LHL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 104 NPTMKVGRQITEVILQHEKKSKKEAKEI--AINLLNDLGIH---EAEKRFeqyphqLSGGMRQRICLAIAFACHPKlVIA 178
Cdd:PRK11288 91 VPEMTVAENLYLGQLPHKGGIVNRRLLNyeAREQLEHLGVDidpDTPLKY------LSIGQRQMVEIAKALARNAR-VIA 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 179 -DEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGRIVE 235
Cdd:PRK11288 164 fDEPTSSLSAREIEQLFRVIRELR-AEGRVILYVSHRMEEIFALCDAITVFKDGRYVA 220
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
155-243 |
3.39e-05 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 45.49 E-value: 3.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKeKQNTSILLITHDLALVREVADRVVVMYGGR-- 232
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELA-KKDKGIIIISSEMPELLGITDRILVMSNGLva 470
|
90
....*....|...
gi 446453403 233 -IVE-KGTIQEVI 243
Cdd:PRK10982 471 gIVDtKTTTQNEI 483
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
24-243 |
4.79e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 45.12 E-value: 4.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGEIVALVGESGSGKSVTAqsiiglnqesiqfddgnisfesKDLTNLQE-SE-WNQIRGKDIsfifqDPlS 101
Cdd:NF033858 282 VDHVSFRIRRGEIFGFLGSNGCGKSTTM----------------------KMLTGLLPaSEgEAWLFGQPV-----DA-G 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 102 SLNPTMKVG--------------RQitevilqhekkskkeakeiaiNL-----LNDLG-------IHEAEKRF------E 149
Cdd:NF033858 334 DIATRRRVGymsqafslygeltvRQ---------------------NLelharLFHLPaaeiaarVAEMLERFdladvaD 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 150 QYPHQLSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEKQNTSILLITHdlaLVREVA--DRVVV 227
Cdd:NF033858 393 ALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIFISTH---FMNEAErcDRISL 469
|
250
....*....|....*.
gi 446453403 228 MYGGRIVEKGTIQEVI 243
Cdd:NF033858 470 MHAGRVLASDTPAALV 485
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
155-247 |
5.03e-05 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 45.02 E-value: 5.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAiAF----ACHPKLVIADEPTTAL---DVtiqKQIMGLLKERKEKQNTsILLITHDLALVReVADRVVV 227
Cdd:COG0178 827 LSGGEAQRVKLA-SElskrSTGKTLYILDEPTTGLhfhDI---RKLLEVLHRLVDKGNT-VVVIEHNLDVIK-TADWIID 900
|
90 100
....*....|....*....|....*.
gi 446453403 228 M------YGGRIVEKGTIQEVIGSPK 247
Cdd:COG0178 901 LgpeggdGGGEIVAEGTPEEVAKVKA 926
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
155-251 |
1.08e-04 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 43.91 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAiafachpK----------LVIADEPTTAL---DVtiqKQIMGLLKERKEKQNTsILLITHDLALVReV 221
Cdd:PRK00349 831 LSGGEAQRVKLA-------KelskrstgktLYILDEPTTGLhfeDI---RKLLEVLHRLVDKGNT-VVVIEHNLDVIK-T 898
|
90 100 110
....*....|....*....|....*....|....*.
gi 446453403 222 ADRVVVM------YGGRIVEKGTIQEVIGSPKhPYT 251
Cdd:PRK00349 899 ADWIIDLgpeggdGGGEIVATGTPEEVAKVEA-SYT 933
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
138-271 |
2.30e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 43.28 E-value: 2.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 138 DLGIHEAEKRFEQYPH-----------------------QLSGGMRQRICLA---IAFACHPKLVIADEPTTALDVTIQK 191
Cdd:PRK00635 770 EMTAYEAEKFFLDEPSihekihalcslgldylplgrplsSLSGGEIQRLKLAyelLAPSKKPTLYVLDEPTTGLHTHDIK 849
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 192 QIMGLLKERKEkQNTSILLITHDLALVReVADRVVVM------YGGRIVEKGTIQEVIGSPKH------PYTKSlLQAIP 259
Cdd:PRK00635 850 ALIYVLQSLTH-QGHTVVIIEHNMHVVK-VADYVLELgpeggnLGGYLLASCSPEELIHLHTPtakalrPYLSS-PQELP 926
|
170
....*....|....*
gi 446453403 260 NMDD---AEKVLRAI 271
Cdd:PRK00635 927 YLPDpspKPPVPADI 941
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
26-244 |
2.80e-04 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 42.41 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 26 HVSFSINEGEIVALVGESGSGKSVTAQSIIGL---NQESIQFDDGNISFESKD--LTN---LQESEWNQIRGKdisfifq 97
Cdd:PRK10982 16 NVNLKVRPHSIHALMGENGAGKSTLLKCLFGIyqkDSGSILFQGKEIDFKSSKeaLENgisMVHQELNLVLQR------- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 dplsSLNPTMKVGRQITEVILQHEKKSKKEAKEIAINLlnDLGIHEAEKRFEqyphqLSGGMRQRICLAIAFACHPKLVI 177
Cdd:PRK10982 89 ----SVMDNMWLGRYPTKGMFVDQDKMYRDTKAIFDEL--DIDIDPRAKVAT-----LSVSQMQMIEIAKAFSYNAKIVI 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446453403 178 ADEPTTALDvtiQKQIMGLLK--ERKEKQNTSILLITHDLALVREVADRVVVMYGG-----RIVEKGTIQEVIG 244
Cdd:PRK10982 158 MDEPTSSLT---EKEVNHLFTiiRKLKERGCGIVYISHKMEEIFQLCDEITILRDGqwiatQPLAGLTMDKIIA 228
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
12-190 |
3.53e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 42.59 E-value: 3.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 12 LAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSVTAQSIIGLNQEsiqfdDGNISFESKDLTNLQESEWNQIRG-- 89
Cdd:TIGR01271 1223 LTAKYTEAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLST-----EGEIQIDGVSWNSVTLQTWRKAFGvi 1297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 90 KDISFIFQDPL-SSLNPtmkvgrqitevilqHEKKSKKEAKEIAinllNDLGIHEAekrFEQYPHQ-----------LSG 157
Cdd:TIGR01271 1298 PQKVFIFSGTFrKNLDP--------------YEQWSDEEIWKVA----EEVGLKSV---IEQFPDKldfvlvdggyvLSN 1356
|
170 180 190
....*....|....*....|....*....|....
gi 446453403 158 GMRQRICLAIAFACHPKLVIADEPTTALD-VTIQ 190
Cdd:TIGR01271 1357 GHKQLMCLARSILSKAKILLLDEPSAHLDpVTLQ 1390
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
154-219 |
4.44e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 40.67 E-value: 4.44e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446453403 154 QLSGGMRQRICLAIAFA--------ChpKLVIADEPTTALDV-TIQKQIMGLLKERKEKQNTSILLITHDLALVR 219
Cdd:cd03240 115 RCSGGEKVLASLIIRLAlaetfgsnC--GILALDEPTTNLDEeNIEESLAEIIEERKSQKNFQLIVITHDEELVD 187
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
24-258 |
7.45e-04 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 40.76 E-value: 7.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 24 VKHVSFSINEGeIVALVGESGSGKSvtaqSIIglnqESIQF---DDGNISFESKDLTNLQESEWNQIRgkdISFIFQDPL 100
Cdd:COG3593 14 IKDLSIELSDD-LTVLVGENNSGKS----SIL----EALRLllgPSSSRKFDEEDFYLGDDPDLPEIE---IELTFGSLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 101 S--------------------SLNPTMKVGRQITEVILQHEKKSKKEAKEIAI--------NLLNDLGIHEAEKrfEQYP 152
Cdd:COG3593 82 SrllrlllkeedkeeleealeELNEELKEALKALNELLSEYLKELLDGLDLELelsldeleDLLKSLSLRIEDG--KELP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 153 -HQLSGGMRQRICLAIAFACH-------PKLVIADEPTTALDVTIQKQIMGLLKERKEKqNTSILLITHDLALVREV-AD 223
Cdd:COG3593 160 lDRLGSGFQRLILLALLSALAelkrapaNPILLIEEPEAHLHPQAQRRLLKLLKELSEK-PNQVIITTHSPHLLSEVpLE 238
|
250 260 270
....*....|....*....|....*....|....*
gi 446453403 224 RVVVMyggRIVEKGTIQEVIGSPKHPYTKSLLQAI 258
Cdd:COG3593 239 NIRRL---RRDSGGTTSTKLIDLDDEDLRKLLRYL 270
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
155-247 |
1.09e-03 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 40.78 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAFAChpKLV----IADEPTTAL---DVTiqkQIMGLLKERKEKQNTsILLITHDLALVREvADRVVV 227
Cdd:COG0178 486 LSGGEAQRIRLATQIGS--GLVgvlyVLDEPSIGLhqrDND---RLIETLKRLRDLGNT-VIVVEHDEDTIRA-ADYIID 558
|
90 100
....*....|....*....|....*.
gi 446453403 228 M------YGGRIVEKGTIQEVIGSPK 247
Cdd:COG0178 559 IgpgageHGGEVVAQGTPEEILKNPD 584
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
155-237 |
2.03e-03 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 40.15 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIM-----GLL--KERkekqntsiLLITHDLALVrEVADRVVV 227
Cdd:PTZ00243 783 LSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGERVVeecflGALagKTR--------VLATHQVHVV-PRADYVVA 853
|
90
....*....|
gi 446453403 228 MYGGRIVEKG 237
Cdd:PTZ00243 854 LGDGRVEFSG 863
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
23-242 |
2.32e-03 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 39.07 E-value: 2.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 23 IVKHVSFSINEGEIVALVGESGSGKSVTAQSIIG--LNQESIQFDDGNISFESkdltnlqESEW---NQIRGKDISFIFQ 97
Cdd:cd03291 52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGelEPSEGKIKHSGRISFSS-------QFSWimpGTIKENIIFGVSY 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 98 DPLSSLNPTMKVgrQITEVILQHEKKSKKeakeiainLLNDLGIheaekrfeqyphQLSGGMRQRICLAIAFACHPKLVI 177
Cdd:cd03291 125 DEYRYKSVVKAC--QLEEDITKFPEKDNT--------VLGEGGI------------TLSGGQRARISLARAVYKDADLYL 182
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446453403 178 ADEPTTALDVTIQKQIMgllkER---KEKQNTSILLITHDLALVREvADRVVVMYGGRIVEKGTIQEV 242
Cdd:cd03291 183 LDSPFGYLDVFTEKEIF----EScvcKLMANKTRILVTSKMEHLKK-ADKILILHEGSSYFYGTFSEL 245
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
155-213 |
2.37e-03 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 39.73 E-value: 2.37e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 446453403 155 LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKErkekQNTSILLITH 213
Cdd:TIGR00954 583 LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGYMYRLCRE----FGITLFSVSH 637
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
5-49 |
4.24e-03 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 37.61 E-value: 4.24e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 446453403 5 LSLENVTLAVEKENSKQEIVKHVSFSINEGEIVALVGESGSGKSV 49
Cdd:cd03232 4 LTWKNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTT 48
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
155-234 |
6.32e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 38.23 E-value: 6.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446453403 155 LSGGMRQRICLAIAFACHPKLVIADEPTTALDVTIQKQIMGLLKERKEkQNTSILLITHDLALVREVADRVVVMYGGRIV 234
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAA-EGKGVIVISSELPELLGMCDRIYVMNEGRIT 483
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
154-187 |
7.23e-03 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 38.30 E-value: 7.23e-03
10 20 30
....*....|....*....|....*....|....
gi 446453403 154 QLSGGMRQRICLAIAFACHPKLVIADEPTTALDV 187
Cdd:PLN03073 344 TFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL 377
|
|
| |
