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Conserved domains on  [gi|446470226|ref|WP_000548080|]
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MULTISPECIES: AraC family transcriptional regulator [Salmonella]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 13462103)

AraC family transcriptional regulator containing an AraC family helix-turn-helix (HTH) DNA-binding domain, may regulate the expression of genes with diverse biological functions including metabolism, stress response, and virulence

CATH:  1.10.10.10
Gene Ontology:  GO:0003700|GO:0006355|GO:0003677
PubMed:  10473770|15808743|9409145|33837749|11282467

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
178-259 2.69e-23

helix_turn_helix, arabinose operon control protein;


:

Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 90.30  E-value: 2.69e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226   178 WTAQEIARRLAMGTSTLRRRLQRES-QSYRQIIEEVRMSCALSQLQSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPS 256
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKETgTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 446470226   257 QVR 259
Cdd:smart00342  82 EYR 84
PRK09685 super family cl35885
DNA-binding transcriptional activator FeaR; Provisional
 37-259 3.29e-03

DNA-binding transcriptional activator FeaR; Provisional


The actual alignment was detected with superfamily member PRK09685:

Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 38.09  E-value: 3.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226  37 GSKVIIQDDSRLVAGPGELIIIPANTPLEIInqpAQNGFRSDLLLLSPEIIARfktmYVQDYPPANLTSLC--TPMSRSL 114
Cdd:PRK09685  80 GHAIIEQDDRQVQLAAGDITLIDASRPCSIY---PQGLSEQISLLLPRELVEQ----YFPGQKPACAGRLSasLPMVQLS 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 115 TFMWENVLDAVRQGLPVGLQEHQAMGLLL--ALLHDGAAGPllieRRYTLTEQVRQLI-------MLSPAklWtaqeIAR 185
Cdd:PRK09685 153 HRLLQQSMNGPALSETESEALLEALIALLrpALHQRESVQP----RRERQFQKVVALIdqsiqeeILRPE--W----IAG 222

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446470226 186 RLAMGTSTLRRRLQRESQSYRQIIEEVRMSCALSQLQSTTL--PIGEIALRCGYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:PRK09685 223 ELGISVRSLYRLFAEQGLVVAQYIRNRRLDRCADDLRPAADdeKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYR 298
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
178-259 2.69e-23

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 90.30  E-value: 2.69e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226   178 WTAQEIARRLAMGTSTLRRRLQRES-QSYRQIIEEVRMSCALSQLQSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPS 256
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKETgTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 446470226   257 QVR 259
Cdd:smart00342  82 EYR 84
HTH_18 pfam12833
Helix-turn-helix domain;
183-259 7.03e-18

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 75.70  E-value: 7.03e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446470226  183 IARRLAMGTSTLRRRLQRES-QSYRQIIEEVRMSCALSQL-QSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELgLSPKEYLRRLRLERARRLLlEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYR 79
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
154-259 2.27e-16

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 76.36  E-value: 2.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 154 LLIERRYTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRES-QSYRQIIEEVRMSCALSQLQSTTLPIGEIA 232
Cdd:COG2207  145 LLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETgTSPKQYLRELRLERAKRLLAETDLSISEIA 224

                         90       100
                 ....*....|....*....|....*..
gi 446470226 233 LRCGYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:COG2207  225 YELGFSSQSHFSRAFKKRFGVTPSEYR 251
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 141-256 2.57e-15

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 73.88  E-value: 2.57e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 141 LLLALLHDGA-AGPLLIERRYTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRESQSYRQIIEEVRMSCALS 219
Cdd:PRK15185 185 LLTAFLRLPEsYEIILSSAQITLKERVYNIISSSPSRQWKLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAK 264

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 446470226 220 QLQSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPS 256
Cdd:PRK15185 265 LLRIGNHNVNAVALKCGYDSTSYFIQCFKKYFKTTPS 301
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 37-259 3.29e-03

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 38.09  E-value: 3.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226  37 GSKVIIQDDSRLVAGPGELIIIPANTPLEIInqpAQNGFRSDLLLLSPEIIARfktmYVQDYPPANLTSLC--TPMSRSL 114
Cdd:PRK09685  80 GHAIIEQDDRQVQLAAGDITLIDASRPCSIY---PQGLSEQISLLLPRELVEQ----YFPGQKPACAGRLSasLPMVQLS 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 115 TFMWENVLDAVRQGLPVGLQEHQAMGLLL--ALLHDGAAGPllieRRYTLTEQVRQLI-------MLSPAklWtaqeIAR 185
Cdd:PRK09685 153 HRLLQQSMNGPALSETESEALLEALIALLrpALHQRESVQP----RRERQFQKVVALIdqsiqeeILRPE--W----IAG 222

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446470226 186 RLAMGTSTLRRRLQRESQSYRQIIEEVRMSCALSQLQSTTL--PIGEIALRCGYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:PRK09685 223 ELGISVRSLYRLFAEQGLVVAQYIRNRRLDRCADDLRPAADdeKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYR 298
 
Name Accession Description Interval E-value
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
178-259 2.69e-23

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 90.30  E-value: 2.69e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226   178 WTAQEIARRLAMGTSTLRRRLQRES-QSYRQIIEEVRMSCALSQLQSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPS 256
Cdd:smart00342   2 LTLEDLAEALGVSPRHLQRLFKKETgTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTPS 81


                   ...
gi 446470226   257 QVR 259
Cdd:smart00342  82 EYR 84
HTH_18 pfam12833
Helix-turn-helix domain;
183-259 7.03e-18

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 75.70  E-value: 7.03e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446470226  183 IARRLAMGTSTLRRRLQRES-QSYRQIIEEVRMSCALSQL-QSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELgLSPKEYLRRLRLERARRLLlEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYR 79
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
154-259 2.27e-16

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 76.36  E-value: 2.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 154 LLIERRYTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRES-QSYRQIIEEVRMSCALSQLQSTTLPIGEIA 232
Cdd:COG2207  145 LLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETgTSPKQYLRELRLERAKRLLAETDLSISEIA 224

                         90       100
                 ....*....|....*....|....*..
gi 446470226 233 LRCGYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:COG2207  225 YELGFSSQSHFSRAFKKRFGVTPSEYR 251
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 141-256 2.57e-15

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 73.88  E-value: 2.57e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 141 LLLALLHDGA-AGPLLIERRYTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRESQSYRQIIEEVRMSCALS 219
Cdd:PRK15185 185 LLTAFLRLPEsYEIILSSAQITLKERVYNIISSSPSRQWKLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAK 264

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 446470226 220 QLQSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPS 256
Cdd:PRK15185 265 LLRIGNHNVNAVALKCGYDSTSYFIQCFKKYFKTTPS 301
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 121-259 2.29e-14

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 71.34  E-value: 2.29e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 121 VLDAVRQGlpvglQEHQAMGLLLALLHDGAAgpllierrytlTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQR 200
Cdd:COG4977  186 VVDPRRPG-----GQAQFSPLLVPLGHRDPR-----------LARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRA 249

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 201 E-SQSYRQIIEEVRMSCALSQLQSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:COG4977  250 AtGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHFRRAFRRRFGVSPSAYR 309
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 127-257 4.92e-14

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 70.09  E-value: 4.92e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 127 QGLPVGLQEHQAMGLLLALLHDGAAGPLLIE-RRYTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRESQSY 205
Cdd:PRK15186 146 QKLSQDKKEYLIRFLLSEFIYEPEAFALFRElSQNTLAENIYNIIISDISRKWALKDISDSLYMSCSTLKRKLKQENTSF 225

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446470226 206 RQIIEEVRMSCALSQLQSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPSQ 257
Cdd:PRK15186 226 SEVYLNARMNKATKLLRNSEYNITRVAYMCGYDSASYFTCVFKKHFKTTPSE 277
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 129-257 1.82e-13

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 68.41  E-value: 1.82e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 129 LPVGLQEHQAMGLLLALLHDgaagpllierryTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRESQSYRQI 208
Cdd:PRK09978 122 LSVFLEDEHFIPLLLNVLQP------------NMRTRVCTVINNNIAHEWTLARIASELLMSPSLLKKKLREEETSYSQL 189

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 446470226 209 IEEVRMSCALSQLQSTTLPIGEIALRCGYLSGSRFTARFRQHYGCLPSQ 257
Cdd:PRK09978 190 LTECRMQRALQLIVIHGFSIKRVAVSCGYHSVSYFIYVFRNYYGMTPTE 238
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 157-259 1.07e-11

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 63.92  E-value: 1.07e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 157 ERRYTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRE-SQSYRQIIEEVRMSCALSQLQsTTLPIGEIALRC 235
Cdd:COG2169   80 PPRADLVARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHtGVTPKAYARARRLLRARQLLQ-TGLSVTDAAYAA 158

                         90       100
                 ....*....|....*....|....
gi 446470226 236 GYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:COG2169  159 GFGSLSRFYEAFKKLLGMTPSAYR 182
PRK15044 PRK15044
transcriptional regulator SirC; Provisional
 155-255 1.20e-10

transcriptional regulator SirC; Provisional


Pssm-ID: 185004 [Multi-domain]  Cd Length: 295  Bit Score: 60.43  E-value: 1.20e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 155 LIER--RYTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRESQSYRQIIEEVRMSCALSQLQSTTLPIGEIA 232
Cdd:PRK15044 184 FLERaiKITTKEKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIYLDARMNQAIKLLRMGAGNISQVA 263

                         90       100
                 ....*....|....*....|...
gi 446470226 233 LRCGYLSGSRFTARFRQHYGCLP 255
Cdd:PRK15044 264 TMCGYDTPSYFIAIFKRHFKITP 286
PRK09940 PRK09940
transcriptional regulator YdeO; Provisional
 154-258 1.46e-09

transcriptional regulator YdeO; Provisional


Pssm-ID: 182157 [Multi-domain]  Cd Length: 253  Bit Score: 57.02  E-value: 1.46e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 154 LLIERRYTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRESQSYRQIIEEVRMSCAlSQLQSTTLPIGEIAL 233
Cdd:PRK09940 127 LLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHA-KNLIRVEGSVNKIAE 205

                         90       100
                 ....*....|....*....|....*
gi 446470226 234 RCGYLSGSRFTARFRQHYGCLPSQV 258
Cdd:PRK09940 206 QCGYASTSYFIYAFRKHFGNSPKRV 230
ftrA PRK09393
transcriptional activator FtrA; Provisional
 162-259 1.03e-07

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 51.89  E-value: 1.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 162 LTEQVRQlimlSPAKLWTAQEIARRLAMGTSTLRRRLQRES--QSYRQIIEEvRMSCALSQLQSTTLPIGEIALRCGYLS 239
Cdd:PRK09393 223 LIDWMRA----HLAEPHTVASLAARAAMSPRTFLRRFEAATgmTPAEWLLRE-RLARARDLLESSALSIDQIAERAGFGS 297

                         90       100
                 ....*....|....*....|
gi 446470226 240 GSRFTARFRQHYGCLPSQVR 259
Cdd:PRK09393 298 EESLRHHFRRRAATSPAAYR 317
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
147-259 2.11e-04

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 41.58  E-value: 2.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 147 HDGAAGPLLIERRYTLTEQVRQLIMLSPAKLWTAQEIARRLAMGTSTLRRRLQRES-QSYRQIIEEVRMSCALSQLQSTT 225
Cdd:PRK13502 162 HRYATDDLPATSRETLLDKLITALANSLECPFALDAFCQQEQCSERVLRQQFRAQTgMTINQYLRQVRICHAQYLLQHSP 241

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446470226 226 LPIGEIALRCGYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:PRK13502 242 LMISEISMQCGFEDSNYFSVVFTRETGMTPSQWR 275
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
164-259 5.84e-04

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 40.34  E-value: 5.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 164 EQVRQLIMLSPAklwtaqeiarRLA------MGTSTLRRRlqresqsyrqiiEEVRMSCALSQLQSTTLPIGEIALRCGY 237
Cdd:PRK10572 203 ESVAQHVCLSPS----------RLAhlfrqqLGISVLRWR------------EDQRISRAKLLLQTTRMPIATIGRNVGY 260

                         90       100
                 ....*....|....*....|..
gi 446470226 238 LSGSRFTARFRQHYGCLPSQVR 259
Cdd:PRK10572 261 DDQLYFSRVFKKCTGASPSEFR 282
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 218-259 6.55e-04

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 36.36  E-value: 6.55e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 446470226  218 LSQLQSTTLPIGEIALRCGYlSGSRFTARFRQHYGCLPSQVR 259
Cdd:pfam00165   1 LRENLSTNLTIADIADELGF-SRSYFSRLFKKYTGVTPSQYR 41
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 37-259 3.29e-03

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 38.09  E-value: 3.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226  37 GSKVIIQDDSRLVAGPGELIIIPANTPLEIInqpAQNGFRSDLLLLSPEIIARfktmYVQDYPPANLTSLC--TPMSRSL 114
Cdd:PRK09685  80 GHAIIEQDDRQVQLAAGDITLIDASRPCSIY---PQGLSEQISLLLPRELVEQ----YFPGQKPACAGRLSasLPMVQLS 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446470226 115 TFMWENVLDAVRQGLPVGLQEHQAMGLLL--ALLHDGAAGPllieRRYTLTEQVRQLI-------MLSPAklWtaqeIAR 185
Cdd:PRK09685 153 HRLLQQSMNGPALSETESEALLEALIALLrpALHQRESVQP----RRERQFQKVVALIdqsiqeeILRPE--W----IAG 222

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446470226 186 RLAMGTSTLRRRLQRESQSYRQIIEEVRMSCALSQLQSTTL--PIGEIALRCGYLSGSRFTARFRQHYGCLPSQVR 259
Cdd:PRK09685 223 ELGISVRSLYRLFAEQGLVVAQYIRNRRLDRCADDLRPAADdeKITSIAYKWGFSDSSHFSTAFKQRFGVSPGEYR 298
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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