|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
1-483 |
0e+00 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 902.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 1 MHSKPSRRPFSLALRLTFFISLSTILAFIAFTWFMLHSVENHFAEQDVSDLQQISTTLNRILQSPVDPDDKKISKIKESI 80
Cdd:PRK09835 1 MVSKPFQRPFSLATRLTFFISLATIAAFFAFTWIMIHSVKVHFAEQDINDLKQISATLERVLNHPDETQARRLMTLEDIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 81 ASYRNVALLLLNPRGEVLFSSAQGAALRPAVNSADFSEHSRARDVFLWTVEDPAGPMDTGSEMKMETYRIIASSGQAIFQ 160
Cdd:PRK09835 81 AGYSNVLISLADSHGKTVYHSPGAPDLREFVRDAIPDKDARGGEVFLWSGPTPMMPGHGHGHMEHSNWRMIALPVGPLVD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 161 GKQqNYVMLTGLSINFHLHYLDALKKNLIAIAVVISLLIVLIIRIAVRQGHLPLRNVSNAIKNITSENLDARLEPTRVPI 240
Cdd:PRK09835 161 GKP-IYTLLIALSIDFHLHYINDLKNKLIMTASVISLLIVFIVLLAVHKGHAPIRSVSRQIQNITSKDLDVRLDPQTVPI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 241 ELEQLVISFNHMIGKIEDVFTRQANFSADIAHEIRTPITNLVTQTEIALSQDRTQRELEDVLYSSLEEYNRMTKMVSDML 320
Cdd:PRK09835 240 ELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDML 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 321 FLAQADNNQLIPDRVMFDLRAEVMKVFEFFEAWAEERNITLKFNGMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITV 400
Cdd:PRK09835 320 FLAQADNNQLIPEKKMLDLADEVGKVFDFFEAWAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 401 SIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDVRSTRFILSVP 480
Cdd:PRK09835 400 RCQEVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVISLP 479
|
...
gi 446477883 481 RLE 483
Cdd:PRK09835 480 RLE 482
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
9-480 |
0e+00 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 614.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 9 PFSLALRLTFFISLSTILAFIAFTWFMLHSVENHFAEQDVSDLQQISTTLNRILQSPVDPD---DKKISKIKESIASYRN 85
Cdd:TIGR01386 1 PRSLTLRLALLFAAVTALVFALSGFMLYSSLERHFEERDREELQGKLEQVRRFLRDPADLDediKRLQEKIDDLLVGHSD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 86 VALLLLNPRGEVLFSSAQGAALRPAVNSADFSEHSRARDvflwtvedpagpmdtgseMKMETYRIIASSGQAIFQGKQQ- 164
Cdd:TIGR01386 81 LALSILNPDGRLLFERAQGAALVPAVAANDALLELDQAD------------------AKMTHYRSILRSVAALPGGKGRk 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 165 NYVMLTGLSINFHLHYLDALKKNLIAIAVVISLLIVLIIRIAVRQGHLPLRNVSNAIKNITSENLDARLEPTRVPIELEQ 244
Cdd:TIGR01386 143 PVQITVALDINAHTHLLDALRKWLILIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARISPESLDQRLDPSRAPAELRE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 245 LVISFNHMIGKIEDVFTRQANFSADIAHEIRTPITNLVTQTEIALSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQ 324
Cdd:TIGR01386 223 LAQSFNAMLGRLEDAFQRLSQFSADLAHELRTPLTNLLGQTQVALSQPRTGEEYREVLESNLEELERLSRMVSDMLFLAR 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 325 ADNNQLIPDRVMFDLRAEVMKVFEFFEAWAEERNITLKFNGMpCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIRE 404
Cdd:TIGR01386 303 ADNGQLALERVRLDLAAELAKVAEYFEPLAEERGVRIRVEGE-GLVRGDPQMFRRAISNLLSNALRHTPDGGTITVRIER 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446477883 405 QESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDVRSTRFILSVP 480
Cdd:TIGR01386 382 RSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEAHGGRASAESPDGKTRFILRFP 457
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
148-484 |
1.82e-71 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 232.14 E-value: 1.82e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 148 YRIIASSGQAIFQGKQQNYVMLTGLSINFHLHYLDALKKNLIAIAVVISLLIVLIIRIAVRQGHLPLRNVSNAIKNITSE 227
Cdd:COG5002 45 LLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSEL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 228 NLDARLEPTRVPIELEQ-----LVISFNHMIGKIEDVFTRQANFSADIAHEIRTPITNLVTQTEIALSQDRTQRE-LEDV 301
Cdd:COG5002 125 LLLLLLLGRLSLRLSALllgllLLAAVERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAADDPEeRREY 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 302 LYSSLEEYNRMTKMVSDMLFLAQADNNQLIPDRVMFDLRAEVMKVFEFFEAWAEERNITLKFNGM--PCLVEGDPQMFRR 379
Cdd:COG5002 205 LEIILEEAERLSRLVNDLLDLSRLESGELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPedPLLVLGDPDRLEQ 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 380 AINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEA 459
Cdd:COG5002 285 VLTNLLDNAIKYTPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTGLGLAIVKHIVEA 364
|
330 340
....*....|....*....|....*.
gi 446477883 460 HHGRVQVESDVRS-TRFILSVPRLEK 484
Cdd:COG5002 365 HGGRIWVESEPGKgTTFTITLPLARE 390
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
164-481 |
3.86e-67 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 218.62 E-value: 3.86e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 164 QNYVMLTGLSINFHLHYLDALKKNLIAIAVVISLLIVLIIRIAVRQGHLPLRNVSNAIKNITSENLDARLEPTRVPIELE 243
Cdd:COG0642 11 LLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 244 QLVISFNHMIGKIEDVFTRQANFSADIAHEIRTPITNLVTQTEIALSQ-DRTQRELEDVLYSSLEeynRMTKMVSDMLFL 322
Cdd:COG0642 91 LLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEElDEEQREYLETILRSAD---RLLRLINDLLDL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 323 AQADNNQLIPDRVMFDLRAEVMKVFEFFEAWAEERNITLKFN--GMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITV 400
Cdd:COG0642 168 SRLEAGKLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDlpDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 401 SIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSrqRKGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSV 479
Cdd:COG0642 248 SVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPS--RRGGGTGLGLAIVKRIVELHGGTIEVESEPgKGTTFTVTL 325
|
..
gi 446477883 480 PR 481
Cdd:COG0642 326 PL 327
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
263-483 |
5.15e-60 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 197.05 E-value: 5.15e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 263 QANFSADIAHEIRTPITNLVTQTEIALSQ-DRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQADNNQLIPDRVMFDLRA 341
Cdd:COG2205 16 KSEFLANVSHELRTPLTSILGAAELLLDEeDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESGKLSLELEPVDLAE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 342 EVMKVFEFFEAWAEERNITLKFN--GMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKP 419
Cdd:COG2205 96 LLEEAVEELRPLAEEKGIRLELDlpPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREGDGVRISVSDNGPG 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446477883 420 IPEEHLSRLFDRFYRVDpsRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDVRS-TRFILSVPRLE 483
Cdd:COG2205 176 IPEEELERIFERFYRGD--NSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGgTTFTVTLPLAE 238
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
134-467 |
2.10e-41 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 153.83 E-value: 2.10e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 134 AGPMDTGSEMkmETYRIIASSGQAI-------FQGKQQNyvmltgLSINFHLHYLDALKKnLIAIAVVISLLIVLIIRIA 206
Cdd:NF012163 117 VGPPDPVSDD--GTRRPILVNGQEVgalgaspVERLTRN------TDINFDSQQKRASWL-IVALALLLAALAAFLLARG 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 207 VRQghlPLRNVSNAIKNITSENLDARLEPTRVPiELEQLVISFNHMIGKIEDVFTRQANFSADIAHEIRTPITnlVTQTE 286
Cdd:NF012163 188 LLA---PVKRLVEATHRLAAGDYTTRVTPTSND-ELGKLAQDFNQLASTLEKNEQMRRDFMADISHELRTPLA--VLRAE 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 287 IALSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQADNNQLIPDRVMFDLRAEVMKVFEFFEAWAEERNITLKFNGM 366
Cdd:NF012163 262 LEAIQDGIRKFTPESLDSLQAEVGTLTKLVDDLHDLSMSDEGALAYQKASVDLVPLLEVEGGAFRERFASAGLELEVSLP 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 367 -PCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEG 445
Cdd:NF012163 342 dSSLVFGDRDRLMQLFNNLLENSLRYTDSGGSLHISASQRPKEVTLTVADSAPGVSDEQLARLFERFYRVEVSRNRASGG 421
|
330 340
....*....|....*....|..
gi 446477883 446 SGIGLAIVKSIVEAHHGRVQVE 467
Cdd:NF012163 422 SGLGLAISLNIVQAHGGTLHAA 443
|
|
| AdeS_HK |
NF012226 |
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component ... |
175-480 |
3.41e-37 |
|
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component regulatory system for the AdeABC efflux pump can confer adaptive resistance to certain antibiotics, including tigecycline.
Pssm-ID: 411090 [Multi-domain] Cd Length: 353 Bit Score: 140.13 E-value: 3.41e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 175 NFHLHYLDalkknLIAIAVVI--SLLIVLIIRIAVRQGHL-PLRNVSNAIKNITSENLDARLEPTRV-PIELEQLVISFN 250
Cdd:NF012226 51 WTEFHFVD-----WIWLFTVIlcGSVISLIIGMKLAQRFIvPINFLADAAKKISQGDLSARAEDSQIhSAEISELMHNFN 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 251 HMIGKIEDVFTRQANFSADIAHEIRTPITNLvtqteialsQDRTQRELEDV------LYSS-LEEYNRMTKMVSDMLFLA 323
Cdd:NF012226 126 DMAQKLESSVKNAQVWNAAIAHELRTPITIL---------QGRLQGILDGVfepdpaLFKSlLNQVEGLSHLVEDLRTLS 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 324 QADNNQLIPDRVMFDLRAEVMKVFEFFEAWAEERNITLKFNGMPCLVEGDPQMFRRAINNLLSNALRYTPEGQaITVSIR 403
Cdd:NF012226 197 LVENQQLRLNYESVDLKDSIEKVLKMFEDRLEQAQLTIVLNLTATPVFCDRRRIEQVLIALIDNAIRYANAGK-LKISSS 275
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446477883 404 EQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDVRSTRFILSVP 480
Cdd:NF012226 276 VIQDDWILQIEDEGPGIAEEYQQDLFNPFFRLEQSRNKEFGGTGLGLAVVHAIVIAHKGSIEYSNSQGNSVFTIKLP 352
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
188-467 |
5.29e-36 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 139.21 E-value: 5.29e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 188 LIAIAVVISLLIVLIIRIAVRQghlpLRNVSNAIknitSENLDARLePTRVPIELEQLVISFNHMIGKIEDvftRQ--AN 265
Cdd:PRK11100 191 LLGIALLIGAGVVWWLNRSIRR----LTRYADAV----TEGKPVPL-PKLGSSELRELAQALESMRVKLEG---KAyvEQ 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 266 FSADIAHEIRTPITNLVTQTEI---ALSQDRTQRELEDVLysslEEYNRMTKMVSDMLFLAQADNNQLIPDRVMFDLRAE 342
Cdd:PRK11100 259 YVQTLTHELKSPLAAIRGAAELlqeDPPPEDRARFTGNIL----TQSARLQQLIDRLLELARLEQRQELEVLEPVALAAL 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 343 VMKVFEFFEAWAEERNITLKFNGMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPE 422
Cdd:PRK11100 335 LEELVEAREAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPD 414
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 446477883 423 EHLSRLFDRFY---RvdPSRQRKgeGSGIGLAIVKSIVEAHHGRVQVE 467
Cdd:PRK11100 415 YALPRIFERFYslpR--PANGRK--STGLGLAFVREVARLHGGEVTLR 458
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
270-484 |
7.17e-36 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 137.79 E-value: 7.17e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 270 IAHEIRTPITNlvtqteIALSQDRTQRELEDVLYSSLEEY-----------NRMTKMVSDMLFLAQADNnqliPDRVMFD 338
Cdd:COG5000 208 IAHEIKNPLTP------IQLSAERLRRKLADKLEEDREDLeraldtiirqvDRLKRIVDEFLDFARLPE----PQLEPVD 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 339 LRAEVMKVFEFFEAWAEERNITLKFN--GMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENP 416
Cdd:COG5000 278 LNELLREVLALYEPALKEKDIRLELDldPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDN 357
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446477883 417 GKPIPEEHLSRLFDRFYrvdpsrQRKGEGSGIGLAIVKSIVEAHHGRVQVESDVRS-TRFILSVPRLEK 484
Cdd:COG5000 358 GPGIPEEVLERIFEPFF------TTKPKGTGLGLAIVKKIVEEHGGTIELESRPGGgTTFTIRLPLAEE 420
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
188-465 |
5.46e-34 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 133.24 E-value: 5.46e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 188 LIAIAVVISLLIVLIIRiavrqGHLPLRNVSNAIKNITSENlDARLEPTRVPIELEQLVISFNHMIGKIEDVFTRQANFS 267
Cdd:PRK10337 168 LVALPIMLIILMVLLGR-----ELAPLKKLALALRMRDPDS-ETPLNATGVPSEVRPLVEALNQLFARTHAMMVRERRFT 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 268 ADIAHEIRTPITNLVTQTEIA-LSQDRTQRElEDVLYSSLEEYNRMTKMVSDMLFLAQADNNQLIPD--RVMFD--LRAE 342
Cdd:PRK10337 242 SDAAHELRSPLAALKVQTEVAqLSDDDPQAR-KKALLQLHAGIDRATRLVDQLLTLSRLDSLDNLQDvaEIPLEdlLQSA 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 343 VMKVFEffEAWAEERNITLKFNGMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQEsffdLVIENPGKPIPE 422
Cdd:PRK10337 321 VMDIYH--TAQQAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARN----FTVRDNGPGVTP 394
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 446477883 423 EHLSRLFDRFYRvdPSRQRKgEGSGIGLAIVKSIVEAHHGRVQ 465
Cdd:PRK10337 395 EALARIGERFYR--PPGQEA-TGSGLGLSIVRRIAKLHGMNVS 434
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
267-481 |
7.35e-34 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 131.07 E-value: 7.35e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 267 SADIAHEIRTPITNLVTQTEIA---LSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQADNnqliPDRVMFDLRAEV 343
Cdd:COG4191 146 AAGIAHEINNPLAAILGNAELLrrrLEDEPDPEELREALERILEGAERAAEIVRSLRAFSRRDE----EEREPVDLNELI 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 344 MKVFEFFEAWAEERNITLKFNGMPCL--VEGDPQMFRRAINNLLSNALRYTPEGQA--ITVSIREQESFFDLVIENPGKP 419
Cdd:COG4191 222 DEALELLRPRLKARGIEVELDLPPDLppVLGDPGQLEQVLLNLLINAIDAMEEGEGgrITISTRREGDYVVISVRDNGPG 301
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446477883 420 IPEEHLSRLFDRFYrvdpSRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVPR 481
Cdd:COG4191 302 IPPEVLERIFEPFF----TTKPVGKGTGLGLSISYGIVEKHGGRIEVESEPgGGTTFTITLPL 360
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
177-480 |
1.25e-33 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 131.65 E-value: 1.25e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 177 HLHYLDALKKNLIAIAVVISLLIVLIIRIAVRQGHLPLRNVSNAIKNITSENLDAR--LEPTRvpiELEQLVISFNHMIG 254
Cdd:PRK10604 127 YLYYLHQMRLLDIALLALIGLSLAFPVFLWMRPHWQDMLKLEAAAQRLGDGHLAERihFDEGS---SLERLGVAFNQMAD 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 255 KIEDVFTRQANFSADIAHEIRTPIT----------NLVTQTEIALSQDRTQREledvlyssleeynrmtKMVSDMLFLAQ 324
Cdd:PRK10604 204 NINALIASKKQLIDGIAHELRTPLVrlryrlemsdNLSAAESQALNRDIGQLE----------------ALIEELLTYAR 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 325 ADNNQLIPDRVMFDLRAEVMKVFEFFEAWAEERNITLKFNGMPCLVEGDPQMFRRAINNLLSNALRYTpeGQAITVSIRE 404
Cdd:PRK10604 268 LDRPQNELHLSEPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRYA--HSRVRVSLLL 345
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446477883 405 QESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVE-SDVRSTRFILSVP 480
Cdd:PRK10604 346 DGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMGGSVNCDeSELGGARFSFSWP 422
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
266-481 |
2.65e-33 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 132.22 E-value: 2.65e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 266 FSADIAHEIRTPITNLVTQTEIAlsqdrtQRELEDVLYSSLEEY--------NRMTKMVSDMLFLAQADNNQLIPDRVmf 337
Cdd:COG4251 285 FAYVASHDLREPLRKISGFSQLL------EEDYGDKLDEEGREYlerirdaaERMQALIDDLLAYSRVGRQELEFEPV-- 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 338 DLRAEVMKVFEFFEAWAEERNITLKFNGMPcLVEGDPQMFRRAINNLLSNALRYTPEGQA--ITVSIREQESFFDLVIEN 415
Cdd:COG4251 357 DLNELLEEVLEDLEPRIEERGAEIEVGPLP-TVRGDPTLLRQVFQNLISNAIKYSRPGEPprIEIGAEREGGEWVFSVRD 435
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446477883 416 PGKPIPEEHLSRLFDRFYRVDPSRQRkgEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVPR 481
Cdd:COG4251 436 NGIGIDPEYAEKIFEIFQRLHSRDEY--EGTGIGLAIVKKIVERHGGRIWVESEPgEGATFYFTLPK 500
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
372-480 |
3.92e-33 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 121.60 E-value: 3.92e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 372 GDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPsRQRKGEGSGIGLA 451
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDK-RSRKIGGTGLGLS 79
|
90 100 110
....*....|....*....|....*....|
gi 446477883 452 IVKSIVEAHHGRVQVESDVRS-TRFILSVP 480
Cdd:smart00387 80 IVKKLVELHGGEISVESEPGGgTTFTITLP 109
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
188-467 |
2.94e-32 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 128.51 E-value: 2.94e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 188 LIAIAVVIS-LLIVLIIRIAVrqghlPLRNVSNAIKNITSENL--DARLEptRVPIELEQLVISFNHMIGKIEDVFTRQA 264
Cdd:PRK09470 172 LLVTMLVSTpLLLWLAWSLAK-----PARKLKNAADEVAQGNLrqHPELE--TGPQEFRQAGASFNQMVTALERMMTSQQ 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 265 NFSADIAHEIRTPITNLvtQTEIALSQdRTQREledvlYSSLE----EYNRMTKMVSDMLFLA-QADNNQLIPDRV-MFD 338
Cdd:PRK09470 245 RLLSDISHELRTPLTRL--QLATALLR-RRQGE-----SKELErietEAQRLDSMINDLLVLSrNQQKNHLERETFkANS 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 339 LRAEVMKVFEFfEAwaEERNITLKFNGMP--CLVEGDPQMFRRAINNLLSNALRYTpeGQAITVSIREQESFFDLVIENP 416
Cdd:PRK09470 317 LWSEVLEDAKF-EA--EQMGKSLTVSAPPgpWPINGNPNALASALENIVRNALRYS--HTKIEVAFSVDKDGLTITVDDD 391
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 446477883 417 GKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVE 467
Cdd:PRK09470 392 GPGVPEEEREQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQHRGWVKAE 442
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
265-486 |
7.19e-32 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 126.66 E-value: 7.19e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 265 NFSADIAHEIRTPITNLVTQTEIALSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQadnnqlIPDRVMFDLRAEV- 343
Cdd:PRK11006 206 NFFANVSHELRTPLTVLQGYLEMMQDQPLEGALREKALHTMREQTQRMEGLVKQLLTLSK------IEAAPTIDLNEKVd 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 344 ----MKVFEFfEAWA-EERNITLKFNGMPCL-VEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPG 417
Cdd:PRK11006 280 vpmmLRVLER-EAQTlSQGKHTITFEVDNSLkVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAEFSVEDNG 358
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 418 KPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVPrlEKMI 486
Cdd:PRK11006 359 PGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVgKGTRFSFVLP--ERLI 426
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
191-467 |
1.68e-30 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 123.59 E-value: 1.68e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 191 IAVVISLLIVLIIRIAVRQGHL-PLRNVSNAIKNITSENLDARLEPTRVPiELEQLVISFNHMIGKIEDVFTRQANFSAD 269
Cdd:PRK10549 168 LIVALSTLLAALATFLLARGLLaPVKRLVEGTHKLAAGDFTTRVTPTSRD-ELGRLAQDFNQLASTLEKNEQMRRDFMAD 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 270 IAHEIRTPITNLVTQTEiALsQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQADNNQLIPDRVMFDLRAEVMKVFEF 349
Cdd:PRK10549 247 ISHELRTPLAVLRGELE-AI-QDGVRKFTPESVASLQAEVGTLTKLVDDLHQLSLSDEGALAYRKTPVDLVPLLEVAGGA 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 350 FEAWAEERNITLKFNgMP--CLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSR 427
Cdd:PRK10549 325 FRERFASRGLTLQLS-LPdsATVFGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLTFADSAPGVSDEQLQK 403
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 446477883 428 LFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVE 467
Cdd:PRK10549 404 LFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAA 443
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
372-480 |
1.81e-27 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 105.91 E-value: 1.81e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 372 GDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFdLVIENPGKPIPEEHLSRLFDRFYRVDpsrQRKGEGSGIGLA 451
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEGGELT-LTVEDNGIGIPPEDLPRIFEPFSTAD---KRGGGGTGLGLS 76
|
90 100 110
....*....|....*....|....*....|
gi 446477883 452 IVKSIVEAHHGRVQVESDVRS-TRFILSVP 480
Cdd:pfam02518 77 IVRKLVELLGGTITVESEPGGgTTVTLTLP 106
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-480 |
1.15e-26 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 103.70 E-value: 1.15e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 373 DPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAI 452
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 446477883 453 VKSIVEAHHGRVQVE-SDVRSTRFILSVP 480
Cdd:cd16946 81 CHNIALAHGGTISAEhSPLGGLRLVLTLP 109
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
188-467 |
1.42e-25 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 107.36 E-value: 1.42e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 188 LIAIAVVISLLIVLIIRIAVRQGHLPLRNVSNAIKNITSENLdarlepTRVPI-----ELEQLVISFNHMIGKIEDVFTR 262
Cdd:PRK10755 63 LLVPSLVMVSLTLLICFQAVRWITRPLAELQKELEARTADNL------TPIAIhsstlEIEAVTSALNQLVSRLTSTLDQ 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 263 QANFSADIAHEIRTPIT------NLVTQTEIALSQDRTQReledvlyssleeYNRMTKMVSDMLFLAQADNN-------- 328
Cdd:PRK10755 137 ERLFTADVAHELRTPLAgirlhlELLEKQHHIDVAPLIAR------------LDQMMHTVEQLLQLARAGQSfssghyqt 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 329 -QLIPDrVMFDLRAEvmkvfefFEAWAEERNITLKFNGMPC--LVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQ 405
Cdd:PRK10755 205 vKLLED-VILPSQDE-------LSEMLEQRQQTLLLPESAAdiTVQGDATLLRLLLRNLVENAHRYSPEGSTITIKLSQE 276
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446477883 406 ESFFDLVIENPGKPIPEEHLSRLFDRFYRVDpsrQRKGeGSGIGLAIVKSIVEAHHGRVQVE 467
Cdd:PRK10755 277 DGGAVLAVEDEGPGIDESKCGELSKAFVRMD---SRYG-GIGLGLSIVSRITQLHHGQFFLQ 334
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
378-480 |
2.47e-25 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 99.97 E-value: 2.47e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 378 RRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIV 457
Cdd:cd16952 2 RSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVKHVM 81
|
90 100
....*....|....*....|....
gi 446477883 458 EAHHGRVQVESDV-RSTRFILSVP 480
Cdd:cd16952 82 SRHDARLLIASELgKGSRFTCLFP 105
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
266-482 |
5.38e-25 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 106.02 E-value: 5.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 266 FSADIAHEIRTPITNLVTQTEIaLSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAqadnNQLIPDRVMFDLRAEVMK 345
Cdd:COG5807 150 LAAGIAHEIRNPLTSIKGFLQL-LQESREDSEREEYFNIIISEIDRINTIITELLVLS----KPKKFNFKKLNLNDVLED 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 346 VFEFFEAWAEERNITLKFNGMP--CLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEE 423
Cdd:COG5807 225 VIALLSTEAILKNISIKYDLADdePVINGDKNQLKQVFINLIKNAIEAMETGGNITIKTYVEGDFVVISVKDEGIGIPEE 304
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 424 HLSRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVEAHHGRVQVESDVRS-TRFILSVPRL 482
Cdd:COG5807 305 VLEKIGEPFFTT------KEEGTGLGLSICKKIIEEHNGTIEVESKPGKgTTFTIYLPLY 358
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
270-484 |
5.97e-25 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 105.70 E-value: 5.97e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 270 IAHEIRTPITNLVTQTEIaLSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQadnnQLIPDRVMFDLRAEVMKVFEF 349
Cdd:COG3852 142 LAHEIRNPLTGIRGAAQL-LERELPDDELREYTQLIIEEADRLNNLVDRLLSFSR----PRPPEREPVNLHEVLERVLEL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 350 FEAwAEERNITLKFNGMPCL--VEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFD----------LVIENPG 417
Cdd:COG3852 217 LRA-EAPKNIRIVRDYDPSLpeVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRVERQVTLgglrprlyvrIEVIDNG 295
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446477883 418 KPIPEEHLSRLFDRFYRvdpsrqRKGEGSGIGLAIVKSIVEAHHGRVQVESDVRS-TRFILSVPRLEK 484
Cdd:COG3852 296 PGIPEEILDRIFEPFFT------TKEKGTGLGLAIVQKIVEQHGGTIEVESEPGKgTTFRIYLPLEQA 357
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
266-480 |
3.63e-24 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 105.06 E-value: 3.63e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 266 FSADIAHEIRTPITNLVTQTEI-ALSQDRTQRELEDVLyssLEEYNRMTKMVSDMLFLA--QADNNQlipdrvMFDLRAE 342
Cdd:COG5809 273 LAAGIAHEIRNPLTSLKGFIQLlKDTIDEEQKTYLDIM---LSELDRIESIISEFLVLAkpQAIKYE------PKDLNTL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 343 VMKVFEFFEAWAEERN--ITLKFNG-MPcLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQE-SFFDLVIENPGK 418
Cdd:COG5809 344 IEEVIPLLQPQALLKNvqIELELEDdIP-DILGDENQLKQVFINLLKNAIEAMPEGGNITIETKAEDdDKVVISVTDEGC 422
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446477883 419 PIPEEHLSRLFDRFYrvdpsrQRKGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVP 480
Cdd:COG5809 423 GIPEERLKKLGEPFY------TTKEKGTGLGLMVSYKIIEEHGGKITVESEVgKGTTFSITLP 479
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
377-480 |
6.93e-24 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 96.02 E-value: 6.93e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 377 FRRAINNLLSNALRYTPEGQ-AITVSIREQESFFDLV---IENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAI 452
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEGEvTLRVSLEEEEEDGVQLrfsVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 446477883 453 VKSIVEAHHGRVQVESDVRS-TRFILSVP 480
Cdd:cd16922 81 SKKLVELMGGDISVESEPGQgSTFTFTLP 109
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
268-484 |
1.43e-23 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 103.89 E-value: 1.43e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 268 ADIAHEIRTPITNLVTQTEIaLSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQADNNQLIPdrvmFDLRAEVMKVF 347
Cdd:PRK11360 395 AGVAHEIRNPLTAIRGYVQI-WRQQTSDPPSQEYLSVVLREVDRLNKVIDQLLEFSRPRESQWQP----VSLNALVEEVL 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 348 EFFE--AWAEERNITLKFNGMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSI-REQESFFDLVIENPGKPIPEEH 424
Cdd:PRK11360 470 QLFQtaGVQARVDFETELDNELPPIWADPELLKQVLLNILINAVQAISARGKIRIRTwQYSDGQVAVSIEDNGCGIDPEL 549
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446477883 425 LSRLFDRFYRVDPSrqrkgeGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVPRLEK 484
Cdd:PRK11360 550 LKKIFDPFFTTKAK------GTGLGLALSQRIINAHGGDIEVESEPgVGTTFTLYLPINPQ 604
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
378-480 |
1.12e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 92.45 E-value: 1.12e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 378 RRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSrqRKGEGSGIGLAIVKSIV 457
Cdd:cd16923 2 QRVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNS--RNTEGAGLGLSIAKAII 79
|
90 100
....*....|....*....|...
gi 446477883 458 EAHHGRVQVESDVRSTRFILSVP 480
Cdd:cd16923 80 ELHGGSASAEYDDNHDLFKVRLP 102
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
377-467 |
2.47e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 91.62 E-value: 2.47e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 377 FRRAINNLLSNALRYTPEgqAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSI 456
Cdd:cd16949 1 LARALENVLRNALRYSPS--KILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAERA 78
|
90
....*....|.
gi 446477883 457 VEAHHGRVQVE 467
Cdd:cd16949 79 IEQHGGKIKAS 89
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
370-467 |
3.19e-22 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 91.31 E-value: 3.19e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 370 VEGDPQMFRRAINNLLSNALRYTPEGQaiTVSIREQESFFDLV-IENPGKPIPEEHLSRLFDRFYRVDPsrqRKGEGSGI 448
Cdd:cd16940 7 VQGDALLLFLLLRNLVDNAVRYSPQGS--RVEIKLSADDGAVIrVEDNGPGIDEEELEALFERFYRSDG---QNYGGSGL 81
|
90
....*....|....*....
gi 446477883 449 GLAIVKSIVEAHHGRVQVE 467
Cdd:cd16940 82 GLSIVKRIVELHGGQIFLG 100
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
270-469 |
3.74e-22 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 98.10 E-value: 3.74e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 270 IAHEIRTPIT--NLVTQT-EIALSQDRTQRE------LEDVLYSSLEEYNRMTKmvsDMLFLAQADNNQLI--PDRVMF- 337
Cdd:PRK09303 158 LAHDLRTPLTaaSLALETlELGQIDEDTELKpalieqLQDQARRQLEEIERLIT---DLLEVGRTRWEALRfnPQKLDLg 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 338 DLRAEVMKvfEFFEAWaEERNITLKF---NGMPClVEGDPQMFRRAINNLLSNALRYTPEGQAITVSI------REQESF 408
Cdd:PRK09303 235 SLCQEVIL--ELEKRW-LAKSLEIQTdipSDLPS-VYADQERIRQVLLNLLDNAIKYTPEGGTITLSMlhrttqKVQVSI 310
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446477883 409 FDlviENPGkpIPEEHLSRLFDRFYRVDPSRQRkgEGSGIGLAIVKSIVEAHHGRVQVESD 469
Cdd:PRK09303 311 CD---TGPG--IPEEEQERIFEDRVRLPRDEGT--EGYGIGLSVCRRIVRVHYGQIWVDSE 364
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
265-480 |
5.05e-22 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 98.32 E-value: 5.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 265 NFSADIAHEIRTP---ITNLVT---QTEIALSQDRtqrELEDVLYSsleEYNRMTKMVSDMLFLAQADNNQLIPdrvmFD 338
Cdd:PRK10364 239 HLAAGVAHEIRNPlssIKGLAKyfaERAPAGGEAH---QLAQVMAK---EADRLNRVVSELLELVKPTHLALQA----VD 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 339 LRAEVMKVFEFFEAWAEERNITLKFNGMPCL--VEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENP 416
Cdd:PRK10364 309 LNDLINHSLQLVSQDANSREIQLRFTANDTLpeIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDS 388
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446477883 417 GKPIPEEHLSRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVEAHHGRVQVES-DVRSTRFILSVP 480
Cdd:PRK10364 389 GKGIAADQLEAIFTPYFTT------KAEGTGLGLAVVHNIVEQHGGTIQVASqEGKGATFTLWLP 447
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
267-480 |
4.88e-21 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 95.95 E-value: 4.88e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 267 SADIAHEIRTPITNLVTQTEIALSQDRTQRELEDVLyssLEEYNRMTKMVSDMLFLAQADNNQlipdRVMFDLRAEVMKV 346
Cdd:COG5805 291 AAGIAHEIRNPLTSIKGFLQLLQPGIEDKEEYFDIM---LSELDRIESIISEFLALAKPQAVN----KEKENINELIQDV 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 347 FEFFEAWAEERNITLKFNGM---PClVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEE 423
Cdd:COG5805 364 VTLLETEAILHNIQIRLELLdedPF-IYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEE 442
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446477883 424 HLSRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVP 480
Cdd:COG5805 443 RLKKLGEPFFTT------KEKGTGLGLMVSYKIIENHNGTIDIDSKVgKGTTFTITLP 494
|
|
| TMAO_torS |
TIGR02956 |
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the ... |
263-480 |
7.32e-21 |
|
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems]
Pssm-ID: 274362 [Multi-domain] Cd Length: 968 Bit Score: 96.39 E-value: 7.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 263 QAN-----FSADIAHEIRTPIT------NLVTQTEIALSQdrtQRELEDVLYSSleeyNRMTKMVSDMLFLAQADNNQLI 331
Cdd:TIGR02956 459 EANraksaFLATMSHEIRTPLNgilgtlELLGDTGLTSQQ---QQYLQVINRSG----ESLLDILNDILDYSKIEAGHLS 531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 332 PDRVMFDLRAEVMKVFEFFEAWAEERNITLKFN---GMPCLVEGDPQMFRRAINNLLSNALRYTPEGQaITVSIREQ-ES 407
Cdd:TIGR02956 532 ISPRPFDLNALLDDVHHLMVSRAQLKGIQLRLNipeQLPNWWQGDGPRIRQVLINLVGNAIKFTDRGS-VVLRVSLNdDS 610
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446477883 408 FFDLVIENPGKPIPEEHLSRLFDRFYRVDpSRQRKGeGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVP 480
Cdd:TIGR02956 611 SLLFEVEDTGCGIAEEEQATLFDAFTQAD-GRRRSG-GTGLGLAISQRLVEAMDGELGVESELgVGSCFWFTLP 682
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
193-466 |
1.24e-20 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 94.21 E-value: 1.24e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 193 VVISLLIV----LIIRIAVRqghlPLRNVSNAIKNITSENLDARLePTRVPIELEQLVISFNHMIGKIEDVFTRQANFSA 268
Cdd:PRK09467 160 LAIGLLSVaggwLFIRIQNR----PLVALEHAALQVGKGEIPPPL-REYGASEVRSVTRAFNQMAAGIKQLEDDRTLLMA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 269 DIAHEIRTPITNLVTQTEIALSQDRTqreLEDVLYSSLEEYNRMT-------KMVSDMLFlAQADNNQLIPDRVMfdlra 341
Cdd:PRK09467 235 GVSHDLRTPLTRIRLATEMMSEEDGY---LAESINKDIEECNAIIeqfidylRTGQEMPM-EMADLNALLGEVIA----- 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 342 evmkvfeffeawAE---ERNITLKFNGMPCLVEGDPQMFRRAINNLLSNALRYTpEGQaITVSIREQESFFDLVIENPGK 418
Cdd:PRK09467 306 ------------AEsgyEREIETALQPGPIEVPMNPIAIKRALANLVVNAARYG-NGW-IKVSSGTEGKRAWFQVEDDGP 371
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 446477883 419 PIPEEHLSRLFDRFYRVDpsRQRKGEGSGIGLAIVKSIVEAHHGRVQV 466
Cdd:PRK09467 372 GIPPEQLKHLFQPFTRGD--SARGSSGTGLGLAIVKRIVDQHNGKVEL 417
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
266-480 |
2.23e-20 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 93.01 E-value: 2.23e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 266 FSADIAHEIRTPITnlVTQ--TEIALSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQADNNQLipdrVMFDLRAEV 343
Cdd:COG5806 204 LAASIAHEVRNPLT--VVRgfIQLLQEPELSDEKRKQYIRIALEELDRAEAIITDYLTFAKPQPEKL----EKIDVSEEL 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 344 MKVFEFFEAWAEERNITLKFNGMPCL-VEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPE 422
Cdd:COG5806 278 EHVIDVLSPYANMNNVEIQTELEPGLyIEGDRQKLQQCLINIIKNGIEAMPNGGTLTIDVSIDKNKVIISIKDTGVGMTK 357
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446477883 423 EHLSRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVEAHHGRVQVESDVRS-TRFILSVP 480
Cdd:COG5806 358 EQLERLGEPYFST------KEKGTGLGTMVSYRIIEAMNGTIRVESEVGKgTTFTITLP 410
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-466 |
4.53e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 85.20 E-value: 4.53e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 373 DPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVD-PSRQRKgeGSGIGLA 451
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPrPHSGQK--STGLGLA 78
|
90
....*....|....*
gi 446477883 452 IVKSIVEAHHGRVQV 466
Cdd:cd16945 79 FVQEVAQLHGGRITL 93
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-470 |
1.14e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 84.05 E-value: 1.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 373 DPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEgSGIGLAI 452
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGH-YGMGLYI 79
|
90
....*....|....*...
gi 446477883 453 VKSIVEAHHGRVQVESDV 470
Cdd:cd16975 80 AKNLVEKHGGSLIIENSQ 97
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
379-481 |
1.87e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 83.25 E-value: 1.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 379 RAINNLLSNALRYTpeGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVE 458
Cdd:cd16939 3 RALDNLLRNALRYA--HRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRVAL 80
|
90 100
....*....|....*....|....
gi 446477883 459 AHHGRVQV-ESDVRSTRFILSVPR 481
Cdd:cd16939 81 WHGGHVECdDSELGGACFRLTWPR 104
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
367-468 |
8.75e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 82.18 E-value: 8.75e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 367 PCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGS 446
Cdd:cd16947 11 PIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSRNSAKQGN 90
|
90 100
....*....|....*....|..
gi 446477883 447 GIGLAIVKSIVEAHHGRVQVES 468
Cdd:cd16947 91 GLGLTITKRLAESMGGSIYVNS 112
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
373-466 |
1.24e-18 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 81.38 E-value: 1.24e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 373 DPQMFRRAINNLLSNALRYTPEGQAITVSIREQE-SFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLA 451
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCILEKFRlNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLS 80
|
90
....*....|....*
gi 446477883 452 IVKSIVEAHHGRVQV 466
Cdd:cd16925 81 IVKEFVELHGGTVTV 95
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
354-481 |
4.37e-18 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 86.06 E-value: 4.37e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 354 AEERNITLKFN---GMPCLvEGDPQMFRRAINNLLSNALRYTPEGQA----ITVSIREQESFFDLVIENPGKPIPEEHLS 426
Cdd:COG3290 257 ARERGIDLTIDidsDLPDL-PLSDTDLVTILGNLLDNAIEAVEKLPEeerrVELSIRDDGDELVIEVEDSGPGIPEELLE 335
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 446477883 427 RLFDRFYrvdPSRqrKGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVPR 481
Cdd:COG3290 336 KIFERGF---STK--LGEGRGLGLALVKQIVEKYGGTIEVESEEgEGTVFTVRLPK 386
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
383-480 |
1.62e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 77.75 E-value: 1.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 383 NLLSNALRYTPEGQ--AITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPsrQRKGEGSGIGLAIVKSIVEAH 460
Cdd:cd16921 7 NLLGNAIKFRRPRRppRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHS--REEYEGTGVGLAIVRKIIERH 84
|
90 100
....*....|....*....|.
gi 446477883 461 HGRVQVESDV-RSTRFILSVP 480
Cdd:cd16921 85 GGRIWLESEPgEGTTFYFTLP 105
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
263-480 |
5.83e-17 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 84.40 E-value: 5.83e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 263 QANFSADIAHEIRTPITNLVTQTEIALSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFL--AQADNNQLIPDRVmfDLR 340
Cdd:PRK09959 712 KSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVdkIESGNYQLQPQWV--DIP 789
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 341 AEVMKVFEFFEAWAEERNITLKFNGM---PCLVEGDPQMFRRAINNLLSNALRYTPEGQA-ITVS---IREQESFFDLVI 413
Cdd:PRK09959 790 TLVQNTCHSFGAIAASKSIALSCSSTfpdHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVkITTSlghIDDNHAVIKMTI 869
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446477883 414 ENPGKPIPEEHLSRLFDRFYRVDPSRQRKgeGSGIGLAIVKSIVEAHHGRVQVESDVR-STRFILSVP 480
Cdd:PRK09959 870 MDSGSGLSQEEQQQLFKRYSQTSAGRQQT--GSGLGLMICKELIKNMQGDLSLESHPGiGTTFTITIP 935
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
217-483 |
1.25e-16 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 83.16 E-value: 1.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 217 VSNAIKNITsenLDARLEPTRVPIELEQLvisfnhmigkiedvftRQANFSAdIAHEIRTPITNLVTQTEIAL------- 289
Cdd:PRK10490 638 IANALERLT---LTASEEQARLASEREQL----------------RNALLAA-LSHDLRTPLTVLFGQAEILTldlaseg 697
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 290 -------SQDRTQreledVLYSsleeynrmTKMVSDMLFLA--QADNnqlipdrvmFDLRAEVMKVFEF-------FEAW 353
Cdd:PRK10490 698 spharqaSEIRQQ-----VLNT--------TRLVNNLLDMAriQSGG---------FNLRKEWLTLEEVvgsalqmLEPG 755
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 354 AEERNITLKFNGMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFY 433
Cdd:PRK10490 756 LSGHPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFA 835
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 446477883 434 RVDpsRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDVR---STRFIL---SVPRLE 483
Cdd:PRK10490 836 RGN--KESAIPGVGLGLAICRAIVEVHGGTIWAENRPEggaCFRVTLpleTPPELE 889
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
380-480 |
1.78e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 72.32 E-value: 1.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 380 AINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKgEGSGIGLAIVKSIVEA 459
Cdd:cd16948 9 IIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRNFQ-ESTGMGLYLVKKLCDK 87
|
90 100
....*....|....*....|..
gi 446477883 460 HHGRVQVESDVRS-TRFILSVP 480
Cdd:cd16948 88 LGHKIDVESEVGEgTTFTITFP 109
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
266-490 |
1.06e-14 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 76.90 E-value: 1.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 266 FSADIAHEIRTPITNLVTQTEIALSQDRT--QRELEDVLYSSLEE----YN---RMTKMVSDMLflaQADNNQLipdrvm 336
Cdd:PRK11091 286 FISTISHELRTPLNGIVGLSRILLDTELTaeQRKYLKTIHVSAITlgniFNdiiDMDKMERRKL---QLDNQPI------ 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 337 fDLRAEVMKVFEFFEAWAEERNITLKFN---GMPCLVEGDPQMFRRAINNLLSNALRYTPEGQaITVSI-REQESFFDLV 412
Cdd:PRK11091 357 -DFTDFLADLENLSGLQAEQKGLRFDLEpllPLPHKVITDGTRLRQILWNLISNAVKFTQQGG-VTVRVrYEEGDMLTFE 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 413 IENPGKPIPEEHLSRLFDRFYRV-DPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILS--VPRLEKMIPE 488
Cdd:PRK11091 435 VEDSGIGIPEDELDKIFAMYYQVkDSHGGKPATGTGIGLAVSKRLAQAMGGDITVTSEEgKGSCFTLTihAPAVAEEVED 514
|
..
gi 446477883 489 TQ 490
Cdd:PRK11091 515 AF 516
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
383-481 |
3.05e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 68.60 E-value: 3.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 383 NLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSrqrkGEGSGIGLAIVKSIVEAHHG 462
Cdd:cd16943 10 NLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPV----GEGTGLGLSLSYRIIQKHGG 85
|
90 100
....*....|....*....|
gi 446477883 463 RVQVESDV-RSTRFILSVPR 481
Cdd:cd16943 86 TIRVASVPgGGTRFTIILPI 105
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
241-480 |
4.42e-14 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 74.94 E-value: 4.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 241 ELEQLVISFNHMIGKIEDVFTRQANFSADIAHEIRTPITNLVTQTEIALSQDRTQRELEDV--LYSSLEEYNRMTKMVSD 318
Cdd:PRK11466 422 ELQELVIEHRQARAEAEKASQAKSAFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLraITDSGESLLTILNDILD 501
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 319 MLFLAQADNNQLIPDRVmFDLRAEVMKVFEFFEAWAEERNITLKFN---GMPCLVEGDPQMFRRAINNLLSNALRYTPEG 395
Cdd:PRK11466 502 YSAIEAGGKNVSVSDEP-FEPRPLLESTLQLMSGRVKGRPIRLATDiadDLPTALMGDPRRIRQVITNLLSNALRFTDEG 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 396 qAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQrkgeGSGIGLAIVKSIVEAHHGRVQVESDV-RSTR 474
Cdd:PRK11466 581 -SIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG----GTGLGLTISSRLAQAMGGELSATSTPeVGSC 655
|
....*.
gi 446477883 475 FILSVP 480
Cdd:PRK11466 656 FCLRLP 661
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
378-465 |
8.41e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 67.09 E-value: 8.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 378 RRAINNLLSNALRYTpeGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRqrKGEGSGIGLAIVKSIV 457
Cdd:cd16950 2 KRVLSNLVDNALRYG--GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNAR--GTSGTGLGLAIVQRIS 77
|
....*...
gi 446477883 458 EAHHGRVQ 465
Cdd:cd16950 78 DAHGGSLT 85
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
379-480 |
1.20e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 67.21 E-value: 1.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 379 RAINNLLSNALRYTPEGQA-ITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIV 457
Cdd:cd16953 3 QVLRNLIGNAISFSPPDTGrITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFGQHSGLGLSISRQII 82
|
90 100
....*....|....*....|....*...
gi 446477883 458 EAHHGRVQVE-----SDVRSTRFILSVP 480
Cdd:cd16953 83 EAHGGISVAEnhnqpGQVIGARFTVQLP 110
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
372-468 |
2.14e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 67.27 E-value: 2.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 372 GDPQMFRRAINNLLSNALRYTPEgqAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQrkgeGSGIGLA 451
Cdd:cd16954 33 GERNDLMELLGNLLDNACKWCLE--FVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQRGQRLDEQRP----GQGLGLA 106
|
90
....*....|....*..
gi 446477883 452 IVKSIVEAHHGRVQVES 468
Cdd:cd16954 107 IAKEIVEQYGGELSLSD 123
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
383-468 |
1.56e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 63.63 E-value: 1.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 383 NLLSNALRYTPEGQ--AITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSrqrkGEGSGIGLAIVKSIVEAH 460
Cdd:cd16976 7 NLLQNALDAMGKVEnpRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPV----GKGTGLGLSISYGIVEEH 82
|
....*...
gi 446477883 461 HGRVQVES 468
Cdd:cd16976 83 GGRLSVAN 90
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
263-468 |
3.58e-12 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 68.85 E-value: 3.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 263 QAN-----FSADIAHEIRTP----ITNL-VTQTEiALSQDrTQRELEDVLYSSleeyNRMTKMVSDMLFLAQADNNQLIP 332
Cdd:PRK10841 442 QASqsksmFLATVSHELRTPlygiIGNLdLLQTK-ELPKG-VDRLVTAMNNSS----SLLLKIISDILDFSKIESEQLKI 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 333 DRVMFDLRaEVMK----------------VFEFFEAwaeernitlkfnGMPCLVEGDPQMFRRAINNLLSNALRYTPEGq 396
Cdd:PRK10841 516 EPREFSPR-EVINhitanylplvvkkrlgLYCFIEP------------DVPVALNGDPMRLQQVISNLLSNAIKFTDTG- 581
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446477883 397 AITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVES 468
Cdd:PRK10841 582 CIVLHVRVDGDYLSFRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLINMMDGDISVDS 653
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
383-480 |
1.38e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 60.87 E-value: 1.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 383 NLLSNALR----YTPEGQAITVSIREQES-FFDLVIENPGKPIPEEHLSRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIV 457
Cdd:cd16920 7 NLVRNGIEamseGGCERRELTIRTSPADDrAVTISVKDTGPGIAEEVAGQLFDPFYTT------KSEGLGMGLSICRSII 80
|
90 100
....*....|....*....|....
gi 446477883 458 EAHHGRVQVES-DVRSTRFILSVP 480
Cdd:cd16920 81 EAHGGRLSVESpAGGGATFQFTLP 104
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
266-484 |
1.90e-11 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 66.62 E-value: 1.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 266 FSADIAHEIRTPITNLVTQTEIALSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQADNNQLIPdrvmFDLRAEVMK 345
Cdd:PRK13837 453 LASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQILAFGRKGERNTKP----FDLSELVTE 528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 346 VFEFFEAwAEERNITLKFN--GMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQE---------------SF 408
Cdd:PRK13837 529 IAPLLRV-SLPPGVELDFDqdQEPAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRAKlrapkvlshgvlppgRY 607
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446477883 409 FDLVIENPGKPIPEEHLSRLFDRFYRVdpsrqRKGeGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVPRLEK 484
Cdd:PRK13837 608 VLLRVSDTGAGIDEAVLPHIFEPFFTT-----RAG-GTGLGLATVHGIVSAHAGYIDVQSTVgRGTRFDVYLPPSSK 678
|
|
| HATPase_c_5 |
pfam14501 |
GHKL domain; This family represents the structurally related ATPase domains of histidine ... |
379-479 |
2.46e-11 |
|
GHKL domain; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433996 [Multi-domain] Cd Length: 102 Bit Score: 60.31 E-value: 2.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 379 RAINNLLSNAL---RYTPEGQAITVSIREQESFFDLVIENPgkpipEEHLSRLFDRFyrvdPSRQRKGEGSGIGLAIVKS 455
Cdd:pfam14501 8 VIFGNLLDNAIeacSKIDDNRFIRLKIREKQNFLIIRIENT-----YEGELKFEGKL----PSTKTKGDGHGIGLKSIRR 78
|
90 100
....*....|....*....|....
gi 446477883 456 IVEAHHGRVQVESDvrSTRFILSV 479
Cdd:pfam14501 79 IVKKYGGNLSTEIE--NGIFTLSI 100
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
381-480 |
2.80e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 59.99 E-value: 2.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 381 INNLLSNAL----RYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRkgegsGIGLAIVKSI 456
Cdd:cd16915 5 VGNLIDNALdalaATGAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGER-----GIGLALVRQS 79
|
90 100
....*....|....*....|....*
gi 446477883 457 VEAHHGRVQVES-DVRSTRFILSVP 480
Cdd:cd16915 80 VERLGGSITVESePGGGTTFSIRIP 104
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
383-480 |
3.50e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 57.03 E-value: 3.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 383 NLLSNALRYTPEGQ-AITVSIREQESF----------FDLVIENPGKPIPEEHLSRLFDrfyrvdPSRQRKGEGSGIGLA 451
Cdd:cd16918 7 NLVRNAAQALAGSGgEIILRTRTQRQVtlghprhrlaLRVSVIDNGPGIPPDLQDTIFY------PMVSGRENGTGLGLA 80
|
90 100
....*....|....*....|....*....
gi 446477883 452 IVKSIVEAHHGRVQVESDVRSTRFILSVP 480
Cdd:cd16918 81 IAQNIVSQHGGVIECDSQPGHTVFSVSLP 109
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
262-324 |
1.56e-09 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 53.76 E-value: 1.56e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446477883 262 RQANFSADIAHEIRTPITNLVTQTEIALSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQ 324
Cdd:cd00082 3 AKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
262-328 |
2.54e-09 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 53.37 E-value: 2.54e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446477883 262 RQANFSADIAHEIRTPITNLVTQTEIaLSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQADNN 328
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLEL-LRDEKLDEEQREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
147-484 |
2.61e-09 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 59.26 E-value: 2.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 147 TYRIIASSGQAIFQGKQQNYVMLTGLSINFHLHYLDALKKNLIAIAVVISLLIVLIIRIAVRQGHLPLRNVSNAIKNITS 226
Cdd:COG2972 118 LLLILGLLLIILLLLSLLGWTLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEK 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 227 ENLdARLEPTRvPIELEQLVISFNHMIGKIEDVFTRQanfsadIAHEIRtpitnlvtQTEIALSQDRTQRE-------LE 299
Cdd:COG2972 198 GDL-VRLEVSG-NDEIGILARSFNEMVERIKELIEEV------YELELE--------KKEAELKALQAQINphflfntLN 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 300 DVL-YSSLEEYNRMTKMVSDMLFLAQA---DNNQLIPdrvmfdLRAEV--------MKVFEFfeawaEERnITLKFNgmp 367
Cdd:COG2972 262 SIRwLAELEDPEEAEEMLEALSKLLRYslsKGDELVT------LEEELeliksyleIQKLRF-----GDR-LEVEIE--- 326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 368 clVEGDP---QMFRRAINNLLSNALRY----TPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFyrvdpsrQ 440
Cdd:COG2972 327 --IDEELldlLIPKLILQPLVENAIEHgiepKEGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEEL-------S 397
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 446477883 441 RKGEGSGIGLAIVKSIVEAHHG---RVQVESDV-RSTRFILSVPRLEK 484
Cdd:COG2972 398 SKGEGRGIGLRNVRERLKLYYGeeyGLEIESEPgEGTTVTIRIPLEEE 445
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
262-328 |
7.61e-09 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 52.18 E-value: 7.61e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446477883 262 RQANFSADIAHEIRTPITNLVTQTEIALSQDRT--QRELEDVLYSSLEeynRMTKMVSDMLFLAQADNN 328
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSeeQREYLETILREAE---RLLRLINDLLDLSRIEAG 66
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
373-467 |
7.84e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 53.31 E-value: 7.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 373 DPQMFRRAINNLLSNAL-----RYTPEGQAITVSIREQESFFDLVIENPGKPIPEEHLSRLFDrfyrvdPSRQRKGEGSG 447
Cdd:cd16944 1 DTTQISQVLTNILKNAAeaiegRPSDVGEVRIRVEADQDGRIVLIVCDNGKGFPREMRHRATE------PYVTTRPKGTG 74
|
90 100
....*....|....*....|
gi 446477883 448 IGLAIVKSIVEAHHGRVQVE 467
Cdd:cd16944 75 LGLAIVKKIMEEHGGRISLS 94
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
197-468 |
1.53e-08 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 56.95 E-value: 1.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 197 LLIVLIIRIAvrqGHLPLRNVSNAIKNITS------ENLDArlEPTRvpiELEQLVISFNHMIGKIEDVFTRQANFSADI 270
Cdd:PRK10815 202 LLVIPLLWLA---AWWSLRPIEALAKQVREleegerEQLDP--NPPR---ELTSLVRNLNRLLKNERERYTKYRTTLTDL 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 271 AHEIRTPITnlVTQTeiALSQDRTQREL--EDVLYSSLEEYNRMTKMVSDMLFLA--QADNNQLI----PDRVMFD-LRA 341
Cdd:PRK10815 274 THSLKTPLA--VLQS--TLRSLRSGKQMsvEQAEPIMLEQISRISQQIGYYLHRAsmRSEHNLLSrelhSVAPLLDnLTS 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 342 EVMKVFEffeawaeERNITLKFNGMPCLV-EGDPQMFRRAINNLLSNALRYTPEgqAITVSIREQESFFDLVIENPGKPI 420
Cdd:PRK10815 350 ALNKVYQ-------RKGVNITLDISPEITfVGEKNDFMEVMGNVLDNACKYCLE--FVEISARQTDEHLHIVVEDDGPGI 420
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 446477883 421 PEEHLSRLFDRFYRVDPSRqrkgEGSGIGLAIVKSIVEAHHGRVQVES 468
Cdd:PRK10815 421 PESKRELIFDRGQRADTLR----PGQGLGLSVAREITEQYEGKISAGD 464
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
188-489 |
1.64e-08 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 57.34 E-value: 1.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 188 LIAIAVVISLLIVLIIRIAVrqghlPLRNVSNAIKNITSENLDARLEPTRVPiELEQLVISFNHMIGKIED--------V 259
Cdd:PRK15347 304 LILVLLTSVLFLLLRRYLAK-----PLWRFVDIINKTGPAALEPRLPENRLD-ELGSIAKAYNQLLDTLNEqydtlenkV 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 260 FTR------------QANFS-----ADIAHEIRTPITNLVTQTEiaLSQ----DRTQRELEDVLY----SSLEEYNRM-- 312
Cdd:PRK15347 378 AERtqalaeakqraeQANKRksehlTTISHEIRTPLNGVLGALE--LLQntplTAEQMDLADTARqctlSLLAIINNLld 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 313 -TKMVSDMLFLaQADNNQLIP--DRVMFDLRAEvmkvfeffeawAEERNITLKfngmpCLVEGD-PQMF-------RRAI 381
Cdd:PRK15347 456 fSRIESGQMTL-SLEETALLPllDQAMLTIQGP-----------AQSKSLTLR-----TFVGAHvPLYLhldslrlRQIL 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 382 NNLLSNALRYTPEGQaITVSIREQESFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQrkgeGSGIGLAIVKSIVEAHH 461
Cdd:PRK15347 519 VNLLGNAVKFTETGG-IRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQADTHSQ----GTGLGLTIASSLAKMMG 593
|
330 340
....*....|....*....|....*....
gi 446477883 462 GRVQVESDV-RSTRFILSVPRLEKMIPET 489
Cdd:PRK15347 594 GELTLFSTPgVGSCFSLVLPLNEYAPPEP 622
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
266-468 |
9.84e-08 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 54.86 E-value: 9.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 266 FSADIAHEIRTPI------TNLVTQTEIALSQ-------DRTQREL----EDVL-YSSLEEynrmTKMVsdmlflaqadn 327
Cdd:PRK11107 296 FLANMSHELRTPLngvigfTRQTLKTPLTPTQrdylqtiERSANNLlaiiNDILdFSKLEA----GKLV----------- 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 328 nqL--IPdrvmFDLRAEVMKVFEFFEAWAEERNI--TLKF-NGMPCLVEGDPQMFRRAINNLLSNALRYTPEGQ-AITVS 401
Cdd:PRK11107 361 --LenIP----FSLRETLDEVVTLLAHSAHEKGLelTLNIdPDVPDNVIGDPLRLQQIITNLVGNAIKFTESGNiDILVE 434
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 402 IREQES-FFDLVIE--NPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVES 468
Cdd:PRK11107 435 LRALSNtKVQLEVQirDTGIGISERQQSQLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHS 504
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
354-480 |
1.12e-07 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 54.15 E-value: 1.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 354 AEERNITLKFNgMPCLVE--GDPQMFRRAIN---NLLSNALRY---TPEGQaITVSIREQESFFDLVIENPGKPIPEEHL 425
Cdd:PRK11086 407 ARELGITLIIS-EDSQLPdsGDEDQVHELITilgNLIENALEAvggEEGGE-ISVSLHYRNGWLHCEVSDDGPGIAPDEI 484
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 446477883 426 SRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVP 480
Cdd:PRK11086 485 DAIFDKGYST------KGSNRGVGLYLVKQSVENLGGSIAVESEPgVGTQFFVQIP 534
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
377-480 |
1.41e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 50.07 E-value: 1.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 377 FRRAINNLLSNALRYTPEGQAITVSIREQE---------------SFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSrqr 441
Cdd:cd16919 1 LELAILNLAVNARDAMPEGGRLTIETSNQRvdadyalnyrdlipgNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKEV--- 77
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 446477883 442 kGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVP 480
Cdd:cd16919 78 -GKGTGLGLSMVYGFVKQSGGHLRIYSEPgVGTTVRIYLP 116
|
|
| HATPase_AgrC-ComD-like |
cd16935 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
354-479 |
1.84e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.
Pssm-ID: 340412 [Multi-domain] Cd Length: 134 Bit Score: 49.88 E-value: 1.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 354 AEERNITLKFN-GMPCLVEGDPQMFRRAINNLLSNAL---RYTPEGQA-ITVSIREQESFFDLVIENPgkpiPEEHLSRL 428
Cdd:cd16935 13 AREKGIEFTIEiDIPILLPISPLDLCIIFGNLLDNAIeacAKIDKENRfIHLKIRQKKGFLIISIENS----YEGELKKK 88
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 446477883 429 FDRFYRvdpsrQRKGEGSGIGLAIVKSIVEAHHGRVQVESDvrSTRFILSV 479
Cdd:cd16935 89 NGLFLS-----TKKDKNHGIGLKSIREIVKKYNGNLSIEYE--NGIFTLSI 132
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
338-480 |
1.98e-05 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 47.21 E-value: 1.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 338 DLRAEVMKVFEFFEAWAEERNITLKFNGMPCLVEGDpqmfrRA------INNLLSNALRY----TPEGQaITVSIREQES 407
Cdd:COG3920 360 DLRDYLRELLEPLRDSYGGRGIRIELDGPDVELPAD-----AAvplgliLNELVTNALKHaflsGEGGR-IRVSWRREDG 433
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446477883 408 FFDLVIENPGKPIPEEhlsrlfdrfyrVDPSRqrkgeGSGIGLAIVKSIVEAHHGRVQVESDvRSTRFILSVP 480
Cdd:COG3920 434 RLRLTVSDNGVGLPED-----------VDPPA-----RKGLGLRLIRALVRQLGGTLELDRP-EGTRVRITFP 489
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
213-256 |
2.93e-05 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 41.28 E-value: 2.93e-05
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 446477883 213 PLRNVSNAIKNITSENLDARLEPTRvPIELEQLVISFNHMIGKI 256
Cdd:cd06225 3 PLRRLTEAARRIAEGDLDVRVPVRS-KDEIGELARAFNQMAERL 45
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
213-258 |
4.48e-05 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 41.08 E-value: 4.48e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446477883 213 PLRNVSNAIKNITSENLDARLEPTRVPiELEQLVISFNHMIGKIED 258
Cdd:smart00304 6 PLRRLAEAAQRIADGDLTVRLPVDGRD-EIGELARAFNEMADRLEE 50
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
270-468 |
1.19e-04 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 44.68 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 270 IAHEIRTPITNLVT---QTEIALSQDRTQReLEDVLYSSLEEYNRMTKMVSDMLFLAQADNNQLIPdrvmFDLRAEVMKV 346
Cdd:COG4192 440 LAHELNQPLNAMSMylfSAKKALEQENYAQ-LPTSLDKIEGLIERMDKIIKSLRQFSRKSDTPLQP----VDLRQVIEQA 514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 347 FEFFEAWAEERNITLKFNGMPcLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQESFFDLVIENPGKPIPEehLS 426
Cdd:COG4192 515 WELVESRAKPQQITLHIPDDL-MVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRVAISDNGNGWPL--VD 591
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446477883 427 RLFDRFYrvdpsrQRKGEGSGIGLAIVKSIVEAHHGRVQVES 468
Cdd:COG4192 592 KLFTPFT------TTKEVGLGLGLSICRSIMQQFGGDLYLAS 627
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
270-480 |
1.56e-04 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 43.92 E-value: 1.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 270 IAHEIRTPITNLVTQTEIalsqdrTQRELEDvlySSLEEYnrmTKMVsdmlfLAQADNNQLIPDR----------VMFDL 339
Cdd:PRK11073 137 LAHEIKNPLGGLRGAAQL------LSKALPD---PALTEY---TKVI-----IEQADRLRNLVDRllgpqrpgthVTESI 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 340 RAEVMKVFEFFEAWAEErNITLKFNGMPCLVE--GDPQMFRRAINNLLSNALR-YTPEGQAITvsIREQESF-------- 408
Cdd:PRK11073 200 HKVAERVVQLVSLELPD-NVRLIRDYDPSLPElaHDPDQIEQVLLNIVRNALQaLGPEGGTIT--LRTRTAFqltlhger 276
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446477883 409 FDLV----IENPGKPIPEEHLSRLFdrfYrvdPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDVRSTRFILSVP 480
Cdd:PRK11073 277 YRLAaridIEDNGPGIPPHLQDTLF---Y---PMVSGREGGTGLGLSIARNLIDQHSGKIEFTSWPGHTEFSVYLP 346
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
11-308 |
4.61e-04 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 42.70 E-value: 4.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 11 SLALRLTFFISLSTILAFIAFTWFMLHSVENHFAEQDVSDLQQISTTLNRILQSPVDPDDKKISKIKESIASYRNVALLL 90
Cdd:COG0840 7 LLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 91 LNPRGEVLFSSAQGAALRPAVNSADFSEHSRARDVFLWTVEDPAGPMDTGSEMKMETYRIIASSGQAIFQGKQQNYVMLT 170
Cdd:COG0840 87 ALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAAL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 171 GLSINFHLHYLDALKKNLIAIAVVISLLIVLIIRIAVRQGHLPLRNVSNAIKNITSENLDARLEPTRVPiELEQLVISFN 250
Cdd:COG0840 167 LEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKD-EIGQLADAFN 245
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446477883 251 HMIGKIEDVFTRQANFS---ADIAHEIRTPITNLVTQTEialsqdRTQRELEDVLySSLEE 308
Cdd:COG0840 246 RMIENLRELVGQVRESAeqvASASEELAASAEELAAGAE------EQAASLEETA-AAMEE 299
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
12-488 |
5.76e-04 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 42.41 E-value: 5.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 12 LALRLTFFISLSTILAFIAFTWFMLHSVENHFAEQDVSDLQQISTTLNRILQSPVDPDDKKISKIKESIASYRNVALLLL 91
Cdd:COG2770 40 LLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALA 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 92 NPRGEVLFSSAQGAALRPAVNSADFSEHSRARDVFLWTVEDPAGPMDTGSEMKMETYRIIASSGQAIFQGKQQNYVMLTG 171
Cdd:COG2770 120 LLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLL 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 172 LSINFHLHYLDALkkNLIAIAVVISLLIVLIIRIAVRQGHLPLRNVSNAIKNITSENLDARLEPTRVPiELEQLVISFNH 251
Cdd:COG2770 200 LVVLLEAALAALL--LLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKD-EIGELARAFNR 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 252 MIGKIEDVFT-----RQANFSADIAHEIRTPITNLVTQTEIALSQDRTQRELEDVLYSSLEEYNRMTKMVSDMLFLAQAD 326
Cdd:COG2770 277 MADSLRESIEeaeeeEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALAL 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 327 NNQLIPDRVMFDLRAEVMKVFEFFEAWAEERNITLKFNGMPCLVEGDPQMFRRAINNLLSNALRYTPEGQAITVSIREQE 406
Cdd:COG2770 357 AALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAA 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 407 SFFDLVIENPGKPIPEEHLSRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDVRSTRFILSVPRLEKMI 486
Cdd:COG2770 437 ALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELAEELLLLEGLL 516
|
..
gi 446477883 487 PE 488
Cdd:COG2770 517 LL 518
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
373-490 |
1.54e-03 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 41.19 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 373 DPQMFRRAINNLLSNALRYTPEGQAITVSIREQES---------------FFDLVIENPGKPIPEEHLSRLFDRFYrvdp 437
Cdd:PRK13557 274 DPTQAEVALLNVLINARDAMPEGGRVTIRTRNVEIededlamyhglppgrYVSIAVTDTGSGMPPEILARVMDPFF---- 349
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 446477883 438 SRQRKGEGSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVPRLEKMIPETQ 490
Cdd:PRK13557 350 TTKEEGKGTGLGLSMVYGFAKQSGGAVRIYSEVgEGTTVRLYFPASDQAENPEQ 403
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
384-481 |
2.16e-03 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 38.36 E-value: 2.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446477883 384 LLSNALRYTPEGQA---ITVSIREQESFFDLVIENPGKPIPEEHLSrlfdrfyrvDPSRQRKGegSGIGLAIVKSIVEah 460
Cdd:COG2172 42 AVTNAVRHAYGGDPdgpVEVELELDPDGLEIEVRDEGPGFDPEDLP---------DPYSTLAE--GGRGLFLIRRLMD-- 108
|
90 100
....*....|....*....|.
gi 446477883 461 hgRVQVESDVRSTRFILSVPR 481
Cdd:COG2172 109 --EVEYESDPGGTTVRLVKRL 127
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
445-480 |
7.05e-03 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 39.01 E-value: 7.05e-03
10 20 30
....*....|....*....|....*....|....*..
gi 446477883 445 GSGIGLAIVKSIVEAHHGRVQVESDV-RSTRFILSVP 480
Cdd:COG0643 381 GRGVGMDVVKTNIEALGGTIEIESEPgKGTTFTLRLP 417
|
|
| |
