|
Name |
Accession |
Description |
Interval |
E-value |
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
2-1470 |
0e+00 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 2509.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 2 IERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKL 81
Cdd:COG3096 1 IERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 82 KAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAME 161
Cdd:COG3096 81 KPGVCYAALDVVNSRGQRLLVGVRLQQVAGRDKKVDIKPFIIQGLPEDVKPTDLLTETLDGRQARVLPLNELKEKAEELE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 162 GVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRE 241
Cdd:COG3096 161 GVQFKQFNSITDYHAFMFDLGVTPKRLRSSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 242 NRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNG 321
Cdd:COG3096 241 NRMTLEAIRVTQSDRDLFKHLITEATNYVAADYMRHANERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 322 AEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLAD 401
Cdd:COG3096 321 RESDLEQDYQAASDHLNLVQTALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLAD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 402 YQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADCAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQL 481
Cdd:COG3096 401 YQQALDVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYEL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 482 VVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDI-DELEALHQ 560
Cdd:COG3096 481 VCKIAGEVERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAaEELEELLA 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 561 ELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLLERER 640
Cdd:COG3096 561 ELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLERER 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 641 EAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQV 720
Cdd:COG3096 641 EATVERDELAARKQALESQIERLSQPGGAEDPRLLALAERLGGVLLSEIYDDVTLEDAPYFSALYGPARHAIVVPDLSAV 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 721 TEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSER 800
Cdd:COG3096 721 KEQLAGLEDCPEDLYLIEGDPDSFDDSVFDAEELEDAVVVKLSDRQWRYSRFPEVPLFGRAAREKRLEELRAERDELAEQ 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 801 FATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRIL 880
Cdd:COG3096 801 YAKASFDVQKLQRLHQAFSQFVGGHLAVAFAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 881 PRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFAL 960
Cdd:COG3096 881 PQANLLADETLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFAL 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 961 TEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQR 1040
Cdd:COG3096 961 SEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQ 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1041 ELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAV 1120
Cdd:COG3096 1041 ELEELGVQADAEAEERARIRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKAGWCAV 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1121 MRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQ 1200
Cdd:COG3096 1121 LRLARDNDVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDALRLSEDPRRPERKVQFYIAVYQHLRERIRQ 1200
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1201 DIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNVR 1280
Cdd:COG3096 1201 DIIRTDDPVEAIEQMEIELARLTEELTSREQKLAISSESVANIIRKTIQREQNRIRMLNQGLQNVSFGQVKGVRLNVNIR 1280
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1281 ETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRAPQTIGEELLDYRNYLEMEVEVNRGSDGWLRA 1360
Cdd:COG3096 1281 ETHAQLLDALSEQQEQHQDLFFSNRLTFSEALAKLYQRLNPHIDMGQRSPQTIGEELLDYRNYLELEVEVNRGADGWLRA 1360
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1361 ESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISP 1440
Cdd:COG3096 1361 ESGALSTGEAIGTGMSILLMVVQSWEEESRRLRGKDISPCRLLFLDEAARLDAKSIATLFELCERLDMQLLIAAPENISP 1440
|
1450 1460 1470
....*....|....*....|....*....|
gi 446494780 1441 EKGTTYKLVRKVFQNTEHVHVVGLRGFAPQ 1470
Cdd:COG3096 1441 EKGTTYKLVRKVFNNQEHVHVVGLRGFGQE 1470
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1-1485 |
0e+00 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 2487.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1 MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGK 80
Cdd:PRK04863 1 MIERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 81 LKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAM 160
Cdd:PRK04863 81 LKAGVCYAALDVVNSRGQRVLVGVRLQQVAGRDRKVDIKPFAIQGLPDSVQPTDLLTETVNERQARVLTLNELKDKAAAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 161 EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALR 240
Cdd:PRK04863 161 EGVQFKQFNSITDYHSLMFDLGIIPRRLRSSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 241 ENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHN 320
Cdd:PRK04863 241 ENRMTLEAIRVTQSDRDLFKHLITESTNYVAADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 321 GAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLA 400
Cdd:PRK04863 321 EAESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 401 DYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADCAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQ 480
Cdd:PRK04863 401 DYQQALDVQQTRAIQYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 481 LVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNF-DIDELEALH 559
Cdd:PRK04863 481 LVRKIAGEVSRSEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLdDEDELEQLQ 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 560 QELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLLERE 639
Cdd:PRK04863 561 EELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 640 REAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQ 719
Cdd:PRK04863 641 RELTVERDELAARKQALDEEIERLSQPGGSEDPRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPARHAIVVPDLSD 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 720 VTEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSE 799
Cdd:PRK04863 721 AAEQLAGLEDCPEDLYLIEGDPDSFDDSVFSVEELEKAVVVKIADRQWRYSRFPEVPLFGRAAREKRIEQLRAEREELAE 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 800 RFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRI 879
Cdd:PRK04863 801 RYATLSFDVQKLQRLHQAFSRFIGSHLAVAFEADPEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 880 LPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFA 959
Cdd:PRK04863 881 LPRLNLLADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFA 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 960 LTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQ 1039
Cdd:PRK04863 961 LTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELK 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1040 RELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCA 1119
Cdd:PRK04863 1041 QELQDLGVPADSGAEERARARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGWCA 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1120 VMRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIR 1199
Cdd:PRK04863 1121 VLRLVKDNGVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKVQFYIAVYQHLRERIR 1200
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1200 QDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNV 1279
Cdd:PRK04863 1201 QDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSESVANIIRKTIQREQNRIRMLNQGLQNISFGQVKSVRLNVNV 1280
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1280 RETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRAPQTIGEELLDYRNYLEMEVEVNRGSDGWLR 1359
Cdd:PRK04863 1281 RETHAMLLDALSEQQEQHQDLFNSARLTFSEALAKLYQRLNPHIDMGQRTPQTIGEELLDYRNYLELEVEVNRGADGWLR 1360
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1360 AESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENIS 1439
Cdd:PRK04863 1361 AESGALSTGEAIGTGMSILVMVVQSWEEESRRLRGKDISPCRLLFLDEAARLDAKSIATLFELCERLDMQLLIAAPENIS 1440
|
1450 1460 1470 1480
....*....|....*....|....*....|....*....|....*.
gi 446494780 1440 PEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQA 1485
Cdd:PRK04863 1441 PEKGTTYKLVRKVFNNREHVHVVGLRGFAQLLPDTLPGQDEAESGA 1486
|
|
| MukB |
pfam04310 |
MukB N-terminal; This family represents the N-terminal region of MukB, one of a group of ... |
2-227 |
9.06e-142 |
|
MukB N-terminal; This family represents the N-terminal region of MukB, one of a group of bacterial proteins essential for the movement of nucleoids from mid-cell towards the cell quarters (i.e. chromosome partitioning). The structure of the N-terminal domain consists of an antiparallel six-stranded beta sheet surrounded by one helix on one side and by five helices on the other side. It contains an exposed Walker A loop in an unexpected helix-loop-helix motif (in other proteins, Walker A motifs generally adopt a P loop conformation as part of a strand-loop-helix motif embedded in a conserved topology of alternating helices and (parallel) beta strands).
Pssm-ID: 427856 [Multi-domain] Cd Length: 226 Bit Score: 433.06 E-value: 9.06e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 2 IERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKL 81
Cdd:pfam04310 1 IERGKFQSLTMINWNGFFARTFDLDQLVTTLSGGNGAGKSTTMAAFITALIPDLSLLHFRNTTEAGSTSGSRDKGLYGKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 82 KAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAME 161
Cdd:pfam04310 81 QAGHCYSAIDVANSRGQRLWFGVHLQQVAGRDRKVDITPFAIQGLPEDVQPTDVLLERLDDGHARVRSLNELKDAAAELG 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446494780 162 GVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSG 227
Cdd:pfam04310 161 GARFKQFNSITDYHNFMFDMGVTPKKLRDQRDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSG 226
|
|
| MukB_hinge |
pfam16330 |
MukB hinge domain; The hinge domain of chromosome partition protein MukB is responsible for ... |
644-810 |
1.77e-80 |
|
MukB hinge domain; The hinge domain of chromosome partition protein MukB is responsible for dimerization and is also involved in protein-DNA interactions and conformational flexibility.
Pssm-ID: 435281 [Multi-domain] Cd Length: 167 Bit Score: 261.89 E-value: 1.77e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 644 VERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEH 723
Cdd:pfam16330 1 QERDELAARKERLEKEIERLLQPGGSEDPRLPRLAERLGGVLLSEIYDDISLEDAPYFSALYGPARHAIVVPDLSDAADK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 724 LEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFAT 803
Cdd:pfam16330 81 LNGLEDCPDDLYLIEGDPDSFDESAFSAEELEDAVLVHDSDRQLRYSRFPEVPLFGRAAREKRLEALRAEREELAERYAK 160
|
....*..
gi 446494780 804 LSFDVQK 810
Cdd:pfam16330 161 LAFDVQK 167
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
290-1100 |
5.69e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 83.95 E-value: 5.69e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 290 EFRREL-HTSRQQLAAEQYKHVDMARELAEHngaeGDLEADYQAASDHLNLVQTAL-RQQEKIERYEADLDELQIRLEEQ 367
Cdd:TIGR02168 197 ELERQLkSLERQAEKAERYKELKAELRELEL----ALLVLRLEELREELEELQEELkEAEEELEELTAELQELEEKLEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 368 NEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKelchlpdltaDCAAEWLETF 447
Cdd:TIGR02168 273 RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL----------DELAEELAEL 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 448 QAKELEATEKMLSLEQKMSMAQTAHSQFEQayqlvvaingplaRNEAWDVARELLREGVDQrhLAEQVQPLRMRLSELEQ 527
Cdd:TIGR02168 343 EEKLEELKEELESLEAELEELEAELEELES-------------RLEELEEQLETLRSKVAQ--LELQIASLNNEIERLEA 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 528 RLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDsvsnAREERMALRQEQEQLQSRIQSLMQRApvwLAA 607
Cdd:TIGR02168 408 RLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEE----LQEELERLEEALEELREELEEAEQAL---DAA 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 608 QNSLNQLSEQCgeefTSSQDVTEYLQQLLEREREAIVERDEVGARKNAVdeeIERLSQPGGSEDQRLNALAERFGGVLLS 687
Cdd:TIGR02168 481 ERELAQLQARL----DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEGYEAAIEAALGGRLQAVVVE 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 688 eiyDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEhLEGltDCPEDLYLIEGDPQSFDDSVFSVDELEKAVV-----VKI 762
Cdd:TIGR02168 554 ---NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE-IQG--NDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggVLV 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 763 ADRqwrysrfpevplfGRAARESRIESLHaerevlSERFATLSFDVqktqrlhqafsrfIGSHLAVAFESDP-------- 834
Cdd:TIGR02168 628 VDD-------------LDNALELAKKLRP------GYRIVTLDGDL-------------VRPGGVITGGSAKtnssiler 675
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 835 EAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNllaDDSLADRVDEIRERLDEAQEAARFVQQ 914
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS---RQISALRKDLARLEAEVEQLEERIAQL 752
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 915 FGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEvvQRRAHFSYSDSAEMLSGNSDlneKLRERLE 994
Cdd:TIGR02168 753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA--LREALDELRAELTLLNEEAA---NLRERLE 827
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 995 QAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIR--RDELHAQLSNNR 1072
Cdd:TIGR02168 828 SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRseLEELSEELRELE 907
|
810 820
....*....|....*....|....*...
gi 446494780 1073 SRRNQLEKALTFCEAEMDNLTRKLRKLE 1100
Cdd:TIGR02168 908 SKRSELRRELEELREKLAQLELRLEGLE 935
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
287-945 |
1.18e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.68 E-value: 1.18e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 287 KALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEAdyqaasdhlnlvQTALRQQEKIeryEADLDELQIRLEE 366
Cdd:COG1196 214 RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL------------EELEAELAEL---EAELEELRLELEE 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 367 QNEVVAEAIERQEenearaeaaelevdELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELchlpdltadcAAEWLET 446
Cdd:COG1196 279 LELELEEAQAEEY--------------ELLAELARLEQDIARLEERRRELEERLEELEEELAE----------LEEELEE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 447 FQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARnEAWDVARELLREGVDQRHLAEQVQPLRMRLSELE 526
Cdd:COG1196 335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE-ELEELAEELLEALRAAAELAAQLEELEEAEEALL 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 527 QRLREQQEAERlladfckrqgknfdidELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLA 606
Cdd:COG1196 414 ERLERLEEELE----------------ELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 607 AQNSLNQLSEQcgeeftssQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLL 686
Cdd:COG1196 478 ALAELLEELAE--------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 687 SEIY-DDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLY---LIEGDPQSFD--DSVFSVDELEKAVVV 760
Cdd:COG1196 550 NIVVeDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAavdLVASDLREADarYYVLGDTLLGRTLVA 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 761 KIADRQWRYS-----RFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAfsrfigshlavafesdpE 835
Cdd:COG1196 630 ARLEAALRRAvtlagRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE-----------------E 692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 836 AEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQF 915
Cdd:COG1196 693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772
|
650 660 670
....*....|....*....|....*....|...
gi 446494780 916 GNQLAKLEPIvsvlqsDP---EQFEQLKEDYAY 945
Cdd:COG1196 773 EREIEALGPV------NLlaiEEYEELEERYDF 799
|
|
| SbcC_Walker_B |
pfam13558 |
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ... |
1335-1425 |
5.35e-14 |
|
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.
Pssm-ID: 463921 [Multi-domain] Cd Length: 90 Bit Score: 68.80 E-value: 5.35e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1335 EELLDYRNYLEMEVEVNR--GSDGWLRAESGALSTGEAIGTGMSILV--MVVQSWEDESRRlrgkdiSPCRLLFLDEA-A 1409
Cdd:pfam13558 1 ARVLDYRNWLSFEVEVRDedGSEVETYRRSGGLSGGEKQLLAYLPLAaaLAAQYGSAEGRP------PAPRLVFLDEAfA 74
|
90
....*....|....*.
gi 446494780 1410 RLDARSIATLFELCER 1425
Cdd:pfam13558 75 KLDEENIRTALELLRA 90
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
230-1149 |
1.12e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 76.63 E-value: 1.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 230 KAFQDMEAALRENRMTLEAIRVTQSDRDLfkHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQykh 309
Cdd:TIGR02168 213 ERYKELKAELRELELALLVLRLEELREEL--EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ--- 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 310 vdmaRELAEHNGAEGDLEADYQAASDHL-NLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAA 388
Cdd:TIGR02168 288 ----KELYALANEISRLEQQKQILRERLaNLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 389 ELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNrakelchlpdltadcaaewletfqaKELEatekmlSLEQKMSMA 468
Cdd:TIGR02168 364 EAELEELESRLEELEEQLETLRSKVAQLELQIASLN-------------------------NEIE------RLEARLERL 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 469 QTAHSQFEQAyqlVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAerlladfckrqgk 548
Cdd:TIGR02168 413 EDRRERLQQE---IEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQA------------- 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 549 nfdIDELEALHQELEARIASLSDSVSNAREERMALRQ---EQEQL---QSRIQSLMQRAPVWLAA-----QNSLNQLseq 617
Cdd:TIGR02168 477 ---LDAAERELAQLQARLDSLERLQENLEGFSEGVKAllkNQSGLsgiLGVLSELISVDEGYEAAieaalGGRLQAV--- 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 618 CGEEFTSSQDVTEYLQQlLEREREAIVERDEVGARKNAVDEEIERLSQPGgsedqrlnalaerFGGVLLSEIYDDVSLED 697
Cdd:TIGR02168 551 VVENLNAAKKAIAFLKQ-NELGRVTFLPLDSIKGTEIQGNDREILKNIEG-------------FLGVAKDLVKFDPKLRK 616
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 698 ApyFSALYGpsrHAIVVPDLSQVTEhLEGLTDCPEDLYLIEGDpqsfddsvfsvdelekavvvkIADRQWRYSRFPEVPL 777
Cdd:TIGR02168 617 A--LSYLLG---GVLVVDDLDNALE-LAKKLRPGYRIVTLDGD---------------------LVRPGGVITGGSAKTN 669
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 778 FGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFsrfigshlavafesdpEAEIRQLNSRRVELERALSNHEN 857
Cdd:TIGR02168 670 SSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL----------------EEELEQLRKELEELSRQISALRK 733
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 858 DNQQQRIQFEQAKEGVTALNRILPRLN---LLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQsdpE 934
Cdd:TIGR02168 734 DLARLEAEVEQLEERIAQLSKELTELEaeiEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR---A 810
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 935 QFEQLKEDYAYSQQMQRDARQQAFALTEVVQrrahfsysDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQL 1014
Cdd:TIGR02168 811 ELTLLNEEAANLRERLESLERRIAATERRLE--------DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER 882
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1015 SQYNQVLASLKSSYDTKKELLNDLQRELQDIgvradsgaeERARIRRDELHAQLsnnrsrRNQLEKAltfcEAEMDNLTR 1094
Cdd:TIGR02168 883 ASLEEALALLRSELEELSEELRELESKRSEL---------RRELEELREKLAQL------ELRLEGL----EVRIDNLQE 943
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*..
gi 446494780 1095 KLRKLERDYFEMREQVVTAKAGwcavmrmvKDNGVERRLHR--RELAYLSADDLRSM 1149
Cdd:TIGR02168 944 RLSEEYSLTLEEAEALENKIED--------DEEEARRRLKRleNKIKELGPVNLAAI 992
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
498-1435 |
2.10e-12 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 72.26 E-value: 2.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 498 ARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNF---DIDELEALHQELEARIASLSDSVS 574
Cdd:COG4913 240 AHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELleaELEELRAELARLEAELERLEARLD 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 575 NAREERMALRQEQ--------EQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSS---------------QDVTEY 631
Cdd:COG4913 320 ALREELDELEAQIrgnggdrlEQLEREIERLERELEERERRRARLEALLAALGLPLPASaeefaalraeaaallEALEEE 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 632 LQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRL----NALAE---------RFGGVLLseiydDVSLEDA 698
Cdd:COG4913 400 LEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLlalrDALAEalgldeaelPFVGELI-----EVRPEEE 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 699 PYFSA---LYGPSRHAIVVPD--LSQVTEHlegltdcpedlyliegdpqsfddsvfsVDELEKAVVVkiadrqwrysRFP 773
Cdd:COG4913 475 RWRGAierVLGGFALTLLVPPehYAAALRW---------------------------VNRLHLRGRL----------VYE 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 774 EVPLFGRAARESRieslhAEREVLSERfatLSFDVqktqrlhQAFSRFIGSHLAvafesdpeaeiRQLNSRRVELERALS 853
Cdd:COG4913 518 RVRTGLPDPERPR-----LDPDSLAGK---LDFKP-------HPFRAWLEAELG-----------RRFDYVCVDSPEELR 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 854 NHendnqQQRIQFE-QAKEGVTA----LNRILPRLNLLADDSlADRVDEIRERLDEAQEAARFVQQfgnQLAKLEPIVSV 928
Cdd:COG4913 572 RH-----PRAITRAgQVKGNGTRhekdDRRRIRSRYVLGFDN-RAKLAALEAELAELEEELAEAEE---RLEALEAELDA 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 929 LQSDPEQFEQLkEDYAYSQQmqrDARQQAFALTEVVQRRahfsysdsAEMLSGNSDLnEKLRERLEQAEAERTRAREALR 1008
Cdd:COG4913 643 LQERREALQRL-AEYSWDEI---DVASAEREIAELEAEL--------ERLDASSDDL-AALEEQLEELEAELEELEEELD 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1009 ghaaqlsQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNqLEKALTFCEAE 1088
Cdd:COG4913 710 -------ELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELREN-LEERIDALRAR 781
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1089 MDNLTRKLRKLERDYfemreqvvtakagwcavmrmvkdngveRRLHRRELAYLSADdlrsmsdkalgalrlaVADNEHLR 1168
Cdd:COG4913 782 LNRAEEELERAMRAF---------------------------NREWPAETADLDAD----------------LESLPEYL 818
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1169 DVLRmsedpkrperkiqffvavyqhlreRIRQDiirtddpveaieqmeiELSRLTEELtsREQKLAISSRSVANI---IR 1245
Cdd:COG4913 819 ALLD------------------------RLEED----------------GLPEYEERF--KELLNENSIEFVADLlskLR 856
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1246 KTIQREQNRIRMLNQGLQNVSFGQ------VNSVRLNVNVRETHAMLLDVLSeqheqHQDLFNSN-RLTFSEALAKLYQR 1318
Cdd:COG4913 857 RAIREIKERIDPLNDSLKRIPFGPgrylrlEARPRPDPEVREFRQELRAVTS-----GASLFDEElSEARFAALKRLIER 931
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1319 L---NPQIDMGQRapqtigEELLDYRNYLEMEVEVNRGSDG---WLRAESGALSTGE-------AIGtgmSILVMVVQSW 1385
Cdd:COG4913 932 LrseEEESDRRWR------ARVLDVRNHLEFDAEEIDREDGeevETYSSSGGKSGGEkqklayfILA---AALAYQLGLE 1002
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|.
gi 446494780 1386 EDESRRLrgkdispcRLLFLDEA-ARLDARSIATLFELCERLQMQLIIAAP 1435
Cdd:COG4913 1003 GRGRPSF--------RTVVLDEAfSKMDEEFARRALRLFKELGLQLLIATP 1045
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
444-1096 |
3.03e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.79 E-value: 3.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 444 LETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQA-YQLVVAINgpLARNEAWDVARELLREGVDQRHLAEQVQPLRMRL 522
Cdd:COG1196 241 LEELEAELEELEAELEELEAELAELEAELEELRLElEELELELE--EAQAEEYELLAELARLEQDIARLEERRRELEERL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 523 SELEQRLREQQEAERLLADfcKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAp 602
Cdd:COG1196 319 EELEEELAELEEELEELEE--ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA- 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 603 vwLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFG 682
Cdd:COG1196 396 --AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 683 GVLLSEIYDDVSLEDApyfsalygpsrhaivvpdlSQVTEHLEGLtdcpedlyliEGDPQSFDDSVFSVDELEKAVVVKI 762
Cdd:COG1196 474 LLEAALAELLEELAEA-------------------AARLLLLLEA----------EADYEGFLEGVKAALLLAGLRGLAG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 763 ADRQWRysrfpEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAfsrfigSHLAVAFESDPEAEIRQLN 842
Cdd:COG1196 525 AVAVLI-----GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRA------TFLPLDKIRARAALAAALA 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 843 SRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKL 922
Cdd:COG1196 594 RGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 923 EPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEvvqrrahfsysdsaemlsgnsdlnEKLRERLEQAEAERTR 1002
Cdd:COG1196 674 LLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE------------------------EERLEEELEEEALEEQ 729
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1003 AREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADS------GAEE---RARIRRDELHAQLSNNRS 1073
Cdd:COG1196 730 LEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAlgpvnlLAIEeyeELEERYDFLSEQREDLEE 809
|
650 660
....*....|....*....|...
gi 446494780 1074 RRNQLEKALtfceAEMDNLTRKL 1096
Cdd:COG1196 810 ARETLEEAI----EEIDRETRER 828
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
449-1114 |
3.55e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.54 E-value: 3.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 449 AKELEATEKmlSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAW--DVARELLREGVD-QRHLAEQVQPLRmrlSEL 525
Cdd:TIGR02169 229 LKEKEALER--QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLleELNKKIKDLGEEeQLRVKEKIGELE---AEI 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 526 EQRLREQQEAERLLADFCKRQGKNF-DIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVW 604
Cdd:TIGR02169 304 ASLERSIAEKERELEDAEERLAKLEaEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAET 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 605 LAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLLEREREAIV------------------ERDEVGARKNAVDEEIERLSQP 666
Cdd:TIGR02169 384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAdlnaaiagieakineleeEKEDKALEIKKQEWKLEQLAAD 463
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 667 GGSEDQRLNALAERFGGV------LLSEIYD-----DVSLEDAPYFSA---LYGPSRHAIV--VPDLSQVTEHLEGLtdc 730
Cdd:TIGR02169 464 LSKYEQELYDLKEEYDRVekelskLQRELAEaeaqaRASEERVRGGRAveeVLKASIQGVHgtVAQLGSVGERYATA--- 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 731 pedlylIEGDPQSFDDSVFSVDELEKAVVVKIADRQwRYSRFPEVPLfGRAARESRIESLHAEREVLSERFATLSFDvqk 810
Cdd:TIGR02169 541 ------IEVAAGNRLNNVVVEDDAVAKEAIELLKRR-KAGRATFLPL-NKMRDERRDLSILSEDGVIGFAVDLVEFD--- 609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 811 tQRLHQAFSRFIGSHLAVafeSDPEAEIRQL-NSRRVELE--------------RALSNHENDNQQQRIQFEQAKEGVTA 875
Cdd:TIGR02169 610 -PKYEPAFKYVFGDTLVV---EDIEAARRLMgKYRMVTLEgelfeksgamtggsRAPRGGILFSRSEPAELQRLRERLEG 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 876 LNRILprlnlladDSLADRVDEIRERLDEA-QEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDAR 954
Cdd:TIGR02169 686 LKREL--------SSLQSELRRIENRLDELsQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK 757
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 955 QQAFALTEVVQRRAHFSYSDSAEMLSGNSDLN----EKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDT 1030
Cdd:TIGR02169 758 SELKELEARIEELEEDLHKLEEALNDLEARLShsriPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQE 837
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1031 KKELLNDLQRELQDIGVRADSGaeeraRIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQV 1110
Cdd:TIGR02169 838 LQEQRIDLKEQIKSIEKEIENL-----NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQI 912
|
....
gi 446494780 1111 VTAK 1114
Cdd:TIGR02169 913 EKKR 916
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
339-601 |
2.13e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.77 E-value: 2.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 339 LVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQeenearaeaaelevDELKSQLADYQQALDVQQTRAIQYNQ 418
Cdd:COG4942 11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEE--------------KALLKQLAALERRIAALARRIRALEQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 419 AIAALNRAkelchLPDLTADCAAewLETFQAKELEATEKMLSLEQKMSmaqtahsqfEQAYQLVVaingpLARNEAWDVA 498
Cdd:COG4942 77 ELAALEAE-----LAELEKEIAE--LRAELEAQKEELAELLRALYRLG---------RQPPLALL-----LSPEDFLDAV 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 499 RELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKnfDIDELEALHQELEARIASLSDSVSNARE 578
Cdd:COG4942 136 RRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE--ERAALEALKAERQKLLARLEKELAELAA 213
|
250 260
....*....|....*....|...
gi 446494780 579 ERMALRQEQEQLQSRIQSLMQRA 601
Cdd:COG4942 214 ELAELQQEAEELEALIARLEAEA 236
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
520-1256 |
9.38e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.91 E-value: 9.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 520 MRLSELEQRLREQQEAERLLADFCKR-----QGKNFDIDELEALHQELEARIA-------SLSDSVSNAREERMALRQEQ 587
Cdd:TIGR02168 232 LRLEELREELEELQEELKEAEEELEEltaelQELEEKLEELRLEVSELEEEIEelqkelyALANEISRLEQQKQILRERL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 588 EQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLLEREREAIVERDEvgaRKNAVDEEIERLSQPG 667
Cdd:TIGR02168 312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELES---RLEELEEQLETLRSKV 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 668 GSEDQRLNALAERFG--GVLLSEIYDDVSLEDAPYFSALYGPSRHAI--VVPDLSQVTEHLEGLTDCPEDLyliegdpqs 743
Cdd:TIGR02168 389 AQLELQIASLNNEIErlEARLERLEDRRERLQQEIEELLKKLEEAELkeLQAELEELEEELEELQEELERL--------- 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 744 fddsVFSVDELEKAVVVKIADRQWRYSRFPEVplfgraarESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRfig 823
Cdd:TIGR02168 460 ----EEALEELREELEEAEQALDAAERELAQL--------QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGV--- 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 824 shLAVAFESDPEAEIrqlnsrrvELERALSnhENDNQQQRIQFEQAKEGVTAL-NRILPRLNLLADDSLADRvdEIRERL 902
Cdd:TIGR02168 525 --LSELISVDEGYEA--------AIEAALG--GRLQAVVVENLNAAKKAIAFLkQNELGRVTFLPLDSIKGT--EIQGND 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 903 DEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALT---EVVQRRAHFSYSDSAEml 979
Cdd:TIGR02168 591 REILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTldgDLVRPGGVITGGSAKT-- 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 980 sGNSDLN-----EKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAE 1054
Cdd:TIGR02168 669 -NSSILErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1055 ERARIRRD--ELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERR 1132
Cdd:TIGR02168 748 RIAQLSKEltELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1133 LHRRELAYLSadDLRSMSDKALGALRLAVADNEHLRDvlRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAI 1212
Cdd:TIGR02168 828 SLERRIAATE--RRLEDLEEQIEELSEDIESLAAEIE--ELEELIEELESELEALLNERASLEEALALLRSELEELSEEL 903
|
730 740 750 760
....*....|....*....|....*....|....*....|....
gi 446494780 1213 EQMEIELSRLTEELTSREQKLAiSSRSVANIIRKTIQREQNRIR 1256
Cdd:TIGR02168 904 RELESKRSELRRELEELREKLA-QLELRLEGLEVRIDNLQERLS 946
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
8-53 |
1.57e-06 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 46.82 E-value: 1.57e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446494780 8 RSLTLINWNGFFARTFDLDELVTTL-SGGNGAGKSTTMAAFVTALIP 53
Cdd:pfam13555 2 TRLQLINWGTFDGHTIPIDPRGNTLlTGPSGSGKSTLLDAIQTLLVP 48
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
306-663 |
2.65e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 2.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 306 QYKHVDMARELAEHNGA-EGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEAR 384
Cdd:TIGR02169 638 KYRMVTLEGELFEKSGAmTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK 717
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 385 AEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRakELCHLpdltadcaAEWLETFQAKELEATEKMLSLEQK 464
Cdd:TIGR02169 718 IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS--ELKEL--------EARIEELEEDLHKLEEALNDLEAR 787
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 465 MSmaqtaHSQFEQAYQLVVAINGPLARNEAW--DVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLadf 542
Cdd:TIGR02169 788 LS-----HSRIPEIQAELSKLEEEVSRIEARlrEIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL--- 859
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 543 ckrqgkNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLmqRAPVWLAAQNsLNQLSEQCGEEF 622
Cdd:TIGR02169 860 ------NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL--EAQIEKKRKR-LSELKAKLEALE 930
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 446494780 623 TSSQDVTEYLQQLLEREREAIVERDeVGARKNAVDEEIERL 663
Cdd:TIGR02169 931 EELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRAL 970
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
987-1293 |
6.34e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.21 E-value: 6.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 987 EKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRAdSGAEERARIRRDELH- 1065
Cdd:TIGR02168 235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI-SRLEQQKQILRERLAn 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1066 ---------AQLSNNRSRR-------NQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGV 1129
Cdd:TIGR02168 314 lerqleeleAQLEELESKLdelaeelAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1130 ERRLHRRELAYLsaDDLRSMSDKALGALRLAVADNEHLRDVLRMSEdpkrperkiqffvavyqhLRERIRQDIIRTDDPV 1209
Cdd:TIGR02168 394 QIASLNNEIERL--EARLERLEDRRERLQQEIEELLKKLEEAELKE------------------LQAELEELEEELEELQ 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1210 EAIEQMEIELSRLTEELTSREQKLaissrsvaNIIRKTIQREQNRIRMLNQGLQNVSfGQVNSVRLNVNVRETHAMLLDV 1289
Cdd:TIGR02168 454 EELERLEEALEELREELEEAEQAL--------DAAERELAQLQARLDSLERLQENLE-GFSEGVKALLKNQSGLSGILGV 524
|
....
gi 446494780 1290 LSEQ 1293
Cdd:TIGR02168 525 LSEL 528
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
882-1113 |
6.58e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.07 E-value: 6.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 882 RLNLLADDSLADRVDEIRE---RLDEAQEAARFVQQfgnQLAKLEPIVSvlqsDPEQFEQLKEDYAYSQQMQRDAR---- 954
Cdd:COG4913 214 REYMLEEPDTFEAADALVEhfdDLERAHEALEDARE---QIELLEPIRE----LAERYAAARERLAELEYLRAALRlwfa 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 955 QQAFALTEVVQRRAHFSYSDSAEMLSGN----SDLNEKLRE-----------RLEQAEAERTRAREALRGHAAQLSQYNQ 1019
Cdd:COG4913 287 QRRLELLEAELEELRAELARLEAELERLearlDALREELDEleaqirgnggdRLEQLEREIERLERELEERERRRARLEA 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1020 VLASLKSSYDTKKELLNDLQRELQDigvradsgAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKL 1099
Cdd:COG4913 367 LLAALGLPLPASAEEFAALRAEAAA--------LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNI 438
|
250
....*....|....
gi 446494780 1100 ERDYFEMREQVVTA 1113
Cdd:COG4913 439 PARLLALRDALAEA 452
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
782-1256 |
6.71e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 6.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 782 ARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRfigsHLAVAfesdpEAEIRQLNSRRVELERALSNHENDNQQ 861
Cdd:COG1196 222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEA----ELAEL-----EAELEELRLELEELELELEEAQAEEYE 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 862 QRIQFEQAKEGVTALNRILPRLNLLADDsLADRVDEIRERLDEAQEAARFVQQfgnQLAKLEPIVSVLQsdpEQFEQLKE 941
Cdd:COG1196 293 LLAELARLEQDIARLEERRRELEERLEE-LEEELAELEEELEELEEELEELEE---ELEEAEEELEEAE---AELAEAEE 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 942 DYAYSQQMQRDARQQAFALTEVVQRRAhfsysdsAEMLSGNSDLNEkLRERLEQAEAERTRAREALRGHAAQLSQYNQVL 1021
Cdd:COG1196 366 ALLEAEAELAEAEEELEELAEELLEAL-------RAAAELAAQLEE-LEEAEEALLERLERLEEELEELEEALAELEEEE 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1022 ASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIR--RDELHAQLSNNRSRRNQLEKALT------------FCEA 1087
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEaaLAELLEELAEAAARLLLLLEAEAdyegflegvkaaLLLA 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1088 EMDNLTRKLRKLERDYFEMREQVVTAKAGWC--------AVMRMVKDNGVERRLHRRELayLSADDLRSMSDKALGALRL 1159
Cdd:COG1196 518 GLRGLAGAVAVLIGVEAAYEAALEAALAAALqnivveddEVAAAAIEYLKAAKAGRATF--LPLDKIRARAALAAALARG 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1160 AVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRS 1239
Cdd:COG1196 596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675
|
490
....*....|....*..
gi 446494780 1240 VANIIRKTIQREQNRIR 1256
Cdd:COG1196 676 EAEAELEELAERLAEEE 692
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
392-1110 |
9.47e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.30 E-value: 9.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 392 VDELKSQLADYQQAldvqqtraiqYNQAIAALNRAKELCHLPDLTADCAAEWLetfQAKELEATEKMLSLEQkmsmAQTA 471
Cdd:COG4913 227 ADALVEHFDDLERA----------HEALEDAREQIELLEPIRELAERYAAARE---RLAELEYLRAALRLWF----AQRR 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 472 HSQFEQAY-QLVVAINGPLARNEAWDVARELLREGVDQRHLA------EQVQPLRMRLSELEQRLREQQEAERLLADFCK 544
Cdd:COG4913 290 LELLEAELeELRAELARLEAELERLEARLDALREELDELEAQirgnggDRLEQLEREIERLERELEERERRRARLEALLA 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 545 RQG--KNFDIDELEALHQELEARIASLSDSVSNAREER-------MALRQEQEQLQSRIQSLMQRA---PVWLAAQnsLN 612
Cdd:COG4913 370 ALGlpLPASAEEFAALRAEAAALLEALEEELEALEEALaeaeaalRDLRRELRELEAEIASLERRKsniPARLLAL--RD 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 613 QLSEQCGEEFTSSQDVTEYLQ-QLLEREREAIVER-----------DEvgARKNAVDEEIERLSQPGGSEDQRLNALAER 680
Cdd:COG4913 448 ALAEALGLDEAELPFVGELIEvRPEEERWRGAIERvlggfaltllvPP--EHYAAALRWVNRLHLRGRLVYERVRTGLPD 525
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 681 FGGVLLSE--IYDDVSLEDAPYFS---ALYGPSRHAIVVPDLSQVTEHLEGLT-DCpedlyLIEGDPQSFDdsvfsvdel 754
Cdd:COG4913 526 PERPRLDPdsLAGKLDFKPHPFRAwleAELGRRFDYVCVDSPEELRRHPRAITrAG-----QVKGNGTRHE--------- 591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 755 ekavvvkIADRQWRYSRfpevPLFGRAAREsRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDP 834
Cdd:COG4913 592 -------KDDRRRIRSR----YVLGFDNRA-KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWD 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 835 EAEIRQLNSRRVELERALSNHENDN---QQQRIQFEQAKEGVTALNRILPRLNLLAdDSLADRVDEIRERLDEAQEAARF 911
Cdd:COG4913 660 EIDVASAEREIAELEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEI-GRLEKELEQAEEELDELQDRLEA 738
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 912 VQQFGnqlaklepivsvlqsDPEQFEQLKEDYAysQQMQRDARQQAFaltevvqrrahfsysdsaemlsgnsdlnEKLRE 991
Cdd:COG4913 739 AEDLA---------------RLELRALLEERFA--AALGDAVERELR----------------------------ENLEE 773
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 992 RLEQAEAERTRAREALRGhaaQLSQYNQVLASLKSSYDTKKELLNDLQRELQdigvradsgaeeraRIRRDELHAqlsnn 1071
Cdd:COG4913 774 RIDALRARLNRAEEELER---AMRAFNREWPAETADLDADLESLPEYLALLD--------------RLEEDGLPE----- 831
|
730 740 750
....*....|....*....|....*....|....*....
gi 446494780 1072 rsRRNQLEKALTfcEAEMDNLTRKLRKLERDYFEMREQV 1110
Cdd:COG4913 832 --YEERFKELLN--ENSIEFVADLLSKLRRAIREIKERI 866
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
230-646 |
1.13e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.15 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 230 KAFQDMEAALRENRMTLEA-IRVTQSDRDLFKHLISEATNYV----AADYMRHANERRVHLDKALEFRRELHTSRQQLAA 304
Cdd:COG4717 91 AELQEELEELEEELEELEAeLEELREELEKLEKLLQLLPLYQeleaLEAELAELPERLEELEERLEELRELEEELEELEA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 305 EQYKHVDMARELAEHNGAE-----GDLEADYQAASDHLNLVQTALRQ-QEKIERYEADLDELQIRLEEQNEvvAEAIERQ 378
Cdd:COG4717 171 ELAELQEELEELLEQLSLAteeelQDLAEELEELQQRLAELEEELEEaQEELEELEEELEQLENELEAAAL--EERLKEA 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 379 EENEARAEAAELEVDELKSQLADYQQALDVQQTRA--------IQYNQAIAALNRAKELCHLPDLTADCAAEWLETFQAK 450
Cdd:COG4717 249 RLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLgllallflLLAREKASLGKEAEELQALPALEELEEEELEELLAAL 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 451 ELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAingpLARNEAWDVARELLRE-GVDQRHLAEQVQPLRMRLSELEQRL 529
Cdd:COG4717 329 GLPPDLSPEELLELLDRIEELQELLREAEELEEE----LQLEELEQEIAALLAEaGVEDEEELRAALEQAEEYQELKEEL 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 530 REQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRiqslmQRAPVWLAAQN 609
Cdd:COG4717 405 EELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEED-----GELAELLQELE 479
|
410 420 430
....*....|....*....|....*....|....*..
gi 446494780 610 SLNQLSEQCGEEFTSSQdvteYLQQLLEREREAIVER 646
Cdd:COG4717 480 ELKAELRELAEEWAALK----LALELLEEAREEYREE 512
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
551-945 |
1.38e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.06 E-value: 1.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 551 DIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTE 630
Cdd:TIGR02168 685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIE 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 631 YLQQLLEREREAIVERDEvgaRKNAVDEEIERLSqpggsedQRLNALAERFGGvlLSEIYDDVSLEdapyfsalygpsrh 710
Cdd:TIGR02168 765 ELEERLEEAEEELAEAEA---EIEELEAQIEQLK-------EELKALREALDE--LRAELTLLNEE-------------- 818
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 711 aivvpdLSQVTEHLEGLTDCPEDLyliegdPQSFDDSVFSVDELEKAVvvkiadrqwrysrfpevplfgrAARESRIESL 790
Cdd:TIGR02168 819 ------AANLRERLESLERRIAAT------ERRLEDLEEQIEELSEDI----------------------ESLAAEIEEL 864
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 791 HAEREVLSERFATLSFDVQKTQRLhqafsrfigSHLAVAFESDPEAEIRQLNSRRVELERALSNhendNQQQRIQFEQAK 870
Cdd:TIGR02168 865 EELIEELESELEALLNERASLEEA---------LALLRSELEELSEELRELESKRSELRRELEE----LREKLAQLELRL 931
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446494780 871 EGVTA-LNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPivsVLQSDPEQFEQLKEDYAY 945
Cdd:TIGR02168 932 EGLEVrIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP---VNLAAIEEYEELKERYDF 1004
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
214-680 |
1.70e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 49.65 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 214 TRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAirvTQSDRDLFKHLISEATNyvAADYMRHANE------------- 280
Cdd:PRK02224 235 TRDEADEVLEEHEERREELETLEAEIEDLRETIAE---TEREREELAEEVRDLRE--RLEELEEERDdllaeaglddada 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 281 -----RRVHLDKAL-EFRRELHTSRQQLAA---EQYKHVDMARELAEHNG----AEGDLEADYQAAsdhlnlvqtalrqQ 347
Cdd:PRK02224 310 eaveaRREELEDRDeELRDRLEECRVAAQAhneEAESLREDADDLEERAEelreEAAELESELEEA-------------R 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 348 EKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQALDVQQTRaIQYNQAIAALNRAK 427
Cdd:PRK02224 377 EAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARER-VEEAEALLEAGKCP 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 428 ElCHLPdLTADCAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVD 507
Cdd:PRK02224 456 E-CGQP-VEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 508 QRhlAEQVQPLRMRLSELEQRLREQQEA---ERLLADFCKRQGKNFDiDELEALHQELEA--RIASLSDSVSNAREERMA 582
Cdd:PRK02224 534 EK--RERAEELRERAAELEAEAEEKREAaaeAEEEAEEAREEVAELN-SKLAELKERIESleRIRTLLAAIADAEDEIER 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 583 LRQEQEQLQSRIQslmQRAPVWLAAQNSLNQLSEQCGEEFTSS-----QDVTEYLQQLLEREREAIVERDEVGARKNAVD 657
Cdd:PRK02224 611 LREKREALAELND---ERRERLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIGAVE 687
|
490 500
....*....|....*....|...
gi 446494780 658 EEIERLSqpggSEDQRLNALAER 680
Cdd:PRK02224 688 NELEELE----ELRERREALENR 706
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
228-637 |
2.71e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.90 E-value: 2.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 228 VRKAFQDMEAALRENRMTLEAIRVTQSD-----RDLFKHLISEATNYVAA--DYMRHANERRVHLDKALEFRRELHTSRQ 300
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEEleeelEQLRKELEELSRQISALrkDLARLEAEVEQLEERIAQLSKELTELEA 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 301 QLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALR-QQEKIERYEADLDELQIRLEEQNEVVAEAIERQE 379
Cdd:TIGR02168 762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDeLRAELTLLNEEAANLRERLESLERRIAATERRLE 841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 380 ENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELchlpdltadcAAEWLETFQAKELEATEKML 459
Cdd:TIGR02168 842 DLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL----------LRSELEELSEELRELESKRS 911
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 460 SLEQKMSMAQTAHSQFEqayqlvvaingplarneawdvarellregvdqrhlaEQVQPLRMRLSELEQRLREQQEAErll 539
Cdd:TIGR02168 912 ELRRELEELREKLAQLE------------------------------------LRLEGLEVRIDNLQERLSEEYSLT--- 952
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 540 adfckrqgknfdIDELEALHQELEAriaslsdsvsnareERMALRQEQEQLQSRIQSLmqrAPVWLAAQNSLNQLSEQcg 619
Cdd:TIGR02168 953 ------------LEEAEALENKIED--------------DEEEARRRLKRLENKIKEL---GPVNLAAIEEYEELKER-- 1001
|
410 420
....*....|....*....|
gi 446494780 620 EEFTSSQ--DVTEYLQQLLE 637
Cdd:TIGR02168 1002 YDFLTAQkeDLTEAKETLEE 1021
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
838-1115 |
6.88e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 47.62 E-value: 6.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 838 IRQLNSRRVELERalsnhendnqqQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAArfvQQFGN 917
Cdd:COG1196 195 LGELERQLEPLER-----------QAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL---EELEA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 918 QLAKLEpivSVLQSDPEQFEQLKEDYaysQQMQRDARQQAFALTEVVQRRAHfsysdsaemlsgNSDLNEKLRERLEQAE 997
Cdd:COG1196 261 ELAELE---AELEELRLELEELELEL---EEAQAEEYELLAELARLEQDIAR------------LEERRRELEERLEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 998 AERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQ--LSNNRSRR 1075
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALraAAELAAQL 402
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 446494780 1076 NQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKA 1115
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
8-428 |
7.08e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 7.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 8 RSLTLINWNGFFAR-TFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLL--------HFRNTTEA----GATSGSRD 74
Cdd:COG4913 4 QRLQLINWGTFDGVhTIDFDGRGTLLTGDNGSGKSTLLDAIQTLLVPAKRPRfnkaandaGKSDRTLLsyvrGKYGSERD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 75 KGLHGK--LKAGVCYS---MLDTINSRHQRVVVGVRLQQVAGRDRKVDIKP-FAIQGLPMSVqptqlvtETLNERqARVL 148
Cdd:COG4913 84 EAGTRPvyLRPGDTWSaiaATFANDGSGQTVTLAQVFWLKGDASSLGDVKRfFVIADGPLDL-------EDFEEF-AHGF 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 149 PLNELKDKLeamEGVQFKQFNSITDYhslmfdlgiiARRLRSA--SDRSKFYRLieasLYGGIS----SAITRSLRDYLL 222
Cdd:COG4913 156 DIRALKARL---KKQGVEFFDSFSAY----------LARLRRRlgIGSEKALRL----LHKTQSfkpiGDLDDFVREYML 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 223 PEnsgvRKAFQDMEAALrENRMTL----EAIRVTQSDRDLFKHLISEATNYVAADymrhanERRVHLDKALEfRRELHTS 298
Cdd:COG4913 219 EE----PDTFEAADALV-EHFDDLerahEALEDAREQIELLEPIRELAERYAAAR------ERLAELEYLRA-ALRLWFA 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 299 RQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQQ--EKIERYEADLDELQIRLEEQNEVVAEAIE 376
Cdd:COG4913 287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNggDRLEQLEREIERLERELEERERRRARLEA 366
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 446494780 377 RQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQ-YNQAIAALNRAKE 428
Cdd:COG4913 367 LLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEaLAEAEAALRDLRR 419
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
298-1102 |
8.68e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.37 E-value: 8.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 298 SRQQLAAEQYKhvDMARELAEHNGAEgdLEADYQAASDHLNLVQTAL-RQQEKIERYEADLDELQIRLEEQNEV---VAE 373
Cdd:TIGR02169 204 RREREKAERYQ--ALLKEKREYEGYE--LLKEKEALERQKEAIERQLaSLEEELEKLTEEISELEKRLEEIEQLleeLNK 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 374 AIERQEEneARAEAAELEVDELKSQLADYQQALDVQQTRAiqyNQAIAALNRAKELCHLPDLTADCAAEWLETFQAKELE 453
Cdd:TIGR02169 280 KIKDLGE--EEQLRVKEKIGELEAEIASLERSIAEKEREL---EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDK 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 454 ATEKMLSLEQKM--------SMAQTAHSQFEQAYQLVVAINGplARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSEL 525
Cdd:TIGR02169 355 LTEEYAELKEELedlraeleEVDKEFAETRDELKDYREKLEK--LKREINELKRELDRLQEELQRLSEELADLNAAIAGI 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 526 EQRLREQQEAERLLAdfckrqgknfdiDELEALHQELEariaSLSDSVSNAREERMALRQEQEQLQSRIQSLMQRapvwL 605
Cdd:TIGR02169 433 EAKINELEEEKEDKA------------LEIKKQEWKLE----QLAADLSKYEQELYDLKEEYDRVEKELSKLQRE----L 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 606 AAQNSLNQLSEQCGEEFTSSQDVTE--------YLQQLLE-REREAIVERDEVGARKNAV---DEE-----IERLSQPGG 668
Cdd:TIGR02169 493 AEAEAQARASEERVRGGRAVEEVLKasiqgvhgTVAQLGSvGERYATAIEVAAGNRLNNVvveDDAvakeaIELLKRRKA 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 669 SEDQRLNALAERFGGVLLSEIYDDVSLE--------DAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTdcpedLYLIEGD 740
Cdd:TIGR02169 573 GRATFLPLNKMRDERRDLSILSEDGVIGfavdlvefDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYR-----MVTLEGE 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 741 PqsfddsvfsvdeLEKAVVVKIADRQWRYSRFPEVPLFGRAARES-RIESLHAEREVLSERFATLSfdvqktQRLHQAFS 819
Cdd:TIGR02169 648 L------------FEKSGAMTGGSRAPRGGILFSRSEPAELQRLReRLEGLKRELSSLQSELRRIE------NRLDELSQ 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 820 RFigshlavafeSDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADrVDEIR 899
Cdd:TIGR02169 710 EL----------SDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEED-LHKLE 778
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 900 ERLD--EAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQqafalTEVVQRRahfsysdsae 977
Cdd:TIGR02169 779 EALNdlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ-----ELQEQRI---------- 843
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 978 mlsgnsDLNEKLRERLEQAEAERTRARE---ALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIgvradSGAE 1054
Cdd:TIGR02169 844 ------DLKEQIKSIEKEIENLNGKKEEleeELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL-----EAQI 912
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 446494780 1055 ERARIRRDELHAQLSNNRSRRNQLEKALT------FCEAEMDNLTRKLRKLERD 1102
Cdd:TIGR02169 913 EKKRKRLSELKAKLEALEEELSEIEDPKGedeeipEEELSLEDVQAELQRVEEE 966
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
780-1258 |
9.25e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 47.24 E-value: 9.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 780 RAARESRIESLHAEREVLSERFATLSFDVQKTQ-RLHQAFSRFIGSHLAVAFEsdpEAEIRQLNSRRVELERALSNHEND 858
Cdd:COG1196 255 LEELEAELAELEAELEELRLELEELELELEEAQaEEYELLAELARLEQDIARL---EERRRELEERLEELEEELAELEEE 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 859 NQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQ 938
Cdd:COG1196 332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 939 LKEDYAySQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYN 1018
Cdd:COG1196 412 LLERLE-RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1019 QVLASLKS--------SYDTKKELLNDLQRELQDIG-------------VRADSGAEERARIRRDELHAQLSNNRSRRNQ 1077
Cdd:COG1196 491 ARLLLLLEaeadyegfLEGVKAALLLAGLRGLAGAVavligveaayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAK 570
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1078 LEKAlTFCEAEMDNLTRKLRKLER--------------------------DYFEMREQVVTAKAGWCAVMRMVKDNGVER 1131
Cdd:COG1196 571 AGRA-TFLPLDKIRARAALAAALArgaigaavdlvasdlreadaryyvlgDTLLGRTLVAARLEAALRRAVTLAGRLREV 649
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1132 RLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEA 1211
Cdd:COG1196 650 TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 446494780 1212 IEQMEIELSRLTEE---LTSREQKLAISSRSVANIIRKTIQREQNRIRML 1258
Cdd:COG1196 730 LEAEREELLEELLEeeeLLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| Macoilin |
pfam09726 |
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ... |
536-655 |
1.89e-04 |
|
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.
Pssm-ID: 462859 [Multi-domain] Cd Length: 670 Bit Score: 46.00 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 536 ERLLADFCKRQGknfDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQrapvwlAAQ---NSLN 612
Cdd:pfam09726 398 VRLEQDIKKLKA---ELQASRQTEQELRSQISSLTSLERSLKSELGQLRQENDLLQTKLHNAVS------AKQkdkQTVQ 468
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 446494780 613 QLSEQCGEEftssQDVTEYLQQLLEREREAIVERDEVGARKNA 655
Cdd:pfam09726 469 QLEKRLKAE----QEARASAEKQLAEEKKRKKEEEATAARAVA 507
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
777-1060 |
2.29e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.14 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 777 LFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAfeSDPEAEIRQLNSRRVELERALSNHE 856
Cdd:COG4942 12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI--AALARRIRALEQELAALEAELAELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 857 NDNQQQRIQFEQAKEGVTALNRILPRLNlladdsladRVDEIRERL--DEAQEAARFVQQFGnqlaklepivSVLQSDPE 934
Cdd:COG4942 90 KEIAELRAELEAQKEELAELLRALYRLG---------RQPPLALLLspEDFLDAVRRLQYLK----------YLAPARRE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 935 QFEQLKEDYAYSQQMQRDARQQAFALTEVVQRrahfsysdsaemlsgnsdlNEKLRERLEQAEAERTRAREALRghaAQL 1014
Cdd:COG4942 151 QAEELRADLAELAALRAELEAERAELEALLAE-------------------LEEERAALEALKAERQKLLARLE---KEL 208
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 446494780 1015 SQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIR 1060
Cdd:COG4942 209 AELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
350-1100 |
3.39e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.49 E-value: 3.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 350 IERYEADLDELQIRLEEQNEVVaeaiERQeenearAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAAL-NRAKE 428
Cdd:pfam15921 80 LEEYSHQVKDLQRRLNESNELH----EKQ------KFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLrNQLQN 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 429 LCHLPDlTADCAAEWLETFQAKELEATEK-MLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLA----RNEAWDVARELlr 503
Cdd:pfam15921 150 TVHELE-AAKCLKEDMLEDSNTQIEQLRKmMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMStmhfRSLGSAISKIL-- 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 504 egvdqRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKnfdiDELEALHQELEARIASLSDSVSNAREERMAL 583
Cdd:pfam15921 227 -----RELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ----DRIEQLISEHEVEITGLTEKASSARSQANSI 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 584 RQEQE--QLQSRIQSLMQRAPVwLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLL----EREREAIVERDEVGARKNAVD 657
Cdd:pfam15921 298 QSQLEiiQEQARNQNSMYMRQL-SDLESTVSQLRSELREAKRMYEDKIEELEKQLvlanSELTEARTERDQFSQESGNLD 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 658 EEIERLsqpggsedqrlnaLAErfggvlLSEIYDDVSLEDAPYFSALYGPSRHAIVVpdlsqvtEHLEgltdcpedlyli 737
Cdd:pfam15921 377 DQLQKL-------------LAD------LHKREKELSLEKEQNKRLWDRDTGNSITI-------DHLR------------ 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 738 egdpQSFDDSVFSVDELEKAVVVKIADRQWRYSRfPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQA 817
Cdd:pfam15921 419 ----RELDDRNMEVQRLEALLKAMKSECQGQMER-QMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 818 FSRFIGSHLAVAFESD-----PEAEIRQLNSR---RVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADD 889
Cdd:pfam15921 494 SERTVSDLTASLQEKEraieaTNAEITKLRSRvdlKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIEN 573
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 890 SL-----------------ADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLqsdpeQFEQLKEDYAYSQQMQ-- 950
Cdd:pfam15921 574 MTqlvgqhgrtagamqvekAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDL-----ELEKVKLVNAGSERLRav 648
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 951 RDARQQAFA-LTEVVQRRAHF-SYSDSAEMLSGN--------SDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQV 1020
Cdd:pfam15921 649 KDIKQERDQlLNEVKTSRNELnSLSEDYEVLKRNfrnkseemETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKV 728
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1021 LASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIR--RDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRK 1098
Cdd:pfam15921 729 AMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKeeKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVAN 808
|
..
gi 446494780 1099 LE 1100
Cdd:pfam15921 809 ME 810
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
521-1019 |
3.97e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 521 RLSELEQRLREQQEAERLLADFCKR-QGKNFDIDELEALHQELEARIASLSDSVSNAR--EERMALRQEQEQLQSRIQSL 597
Cdd:COG4717 72 ELKELEEELKEAEEKEEEYAELQEElEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEEL 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 598 MQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEYL-QQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNA 676
Cdd:COG4717 152 EERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 677 LAERfggVLLSEIYDDVSLEDAPYFSAlygpsrhAIVVpdlsqvtehlegltdcpedlyLIEGDPQSFDDSVFSVDELEK 756
Cdd:COG4717 232 LENE---LEAAALEERLKEARLLLLIA-------AALL---------------------ALLGLGGSLLSLILTIAGVLF 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 757 AVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDvqktqrlhqafsrfigSHLAVAFESDPEA 836
Cdd:COG4717 281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLP----------------PDLSPEELLELLD 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 837 EIRQLNSRRVELERAlsnhendnqQQRIQFEQAKEgvtALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFG 916
Cdd:COG4717 345 RIEELQELLREAEEL---------EEELQLEELEQ---EIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLE 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 917 NQLAKLEPivsvlQSDPEQFEQLKEDYA-YSQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQ 995
Cdd:COG4717 413 ELLGELEE-----LLEALDEEELEEELEeLEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRE 487
|
490 500
....*....|....*....|....*..
gi 446494780 996 AEAERTR---AREALRGHAAQLSQYNQ 1019
Cdd:COG4717 488 LAEEWAAlklALELLEEAREEYREERL 514
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
499-957 |
4.58e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 4.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 499 RELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNARE 578
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 579 ERMALRQEQEQLQSRIQSLMQrapvwlaAQNSLNQLSEQCGEEFTSS-QDVTEYLQQLLEREREAIVERDEVGARKNAVD 657
Cdd:COG4717 154 RLEELRELEEELEELEAELAE-------LQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEELE 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 658 EEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLE-GLTDCPEDLYL 736
Cdd:COG4717 227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLArEKASLGKEAEE 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 737 IEGDPQSfddsvfsvDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQ 816
Cdd:COG4717 307 LQALPAL--------EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 817 AFsrfigshlavafeSDPEAEIRQlnsrRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLAD-DSLADRV 895
Cdd:COG4717 379 AG-------------VEDEEELRA----ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEElEELEEEL 441
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446494780 896 DEIRERLDEAQEaarfvqqfgnQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQA 957
Cdd:COG4717 442 EELEEELEELRE----------ELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWA 493
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
335-680 |
6.40e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 44.26 E-value: 6.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 335 DHLNLVQTALRQ-QEKIERYEADLDELQIRLEEQNEVVAEAIERQeenearaeaaeLEVDELKSQLADYQQALDVQQTRA 413
Cdd:PRK02224 206 ERLNGLESELAElDEEIERYEEQREQARETRDEADEVLEEHEERR-----------EELETLEAEIEDLRETIAETERER 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 414 IQYNQAIAALNRAKEL-----------CHLPDLTADCAAEWLETFQAKELEATEkmlSLEQKMSMAQTAHSQFEQayqlv 482
Cdd:PRK02224 275 EELAEEVRDLRERLEEleeerddllaeAGLDDADAEAVEARREELEDRDEELRD---RLEECRVAAQAHNEEAES----- 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 483 vaingplarneawdvarelLREGVDQrhLAEQVQPLRMRLSELEQRLREQQEAERlladfcKRQGKnfdIDELEALHQEL 562
Cdd:PRK02224 347 -------------------LREDADD--LEERAEELREEAAELESELEEAREAVE------DRREE---IEELEEEIEEL 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 563 EARIASLSDSVSNAREERMALRQEQEQLQSRIQSLmqRAPVwLAAQNSLNQLSE--------QCGEEFTSSQDVtEYLQQ 634
Cdd:PRK02224 397 RERFGDAPVDLGNAEDFLEELREERDELREREAEL--EATL-RTARERVEEAEAlleagkcpECGQPVEGSPHV-ETIEE 472
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 446494780 635 LLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDqRLNALAER 680
Cdd:PRK02224 473 DRERVEELEAELEDLEEEVEEVEERLERAEDLVEAED-RIERLEER 517
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
835-1143 |
7.00e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 7.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 835 EAEIRQLNSRRVELERALsnhendnQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQeaarfvqq 914
Cdd:TIGR02169 236 ERQKEAIERQLASLEEEL-------EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELE-------- 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 915 fgNQLAKLEPIVSVLQSDPEQFE-QLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFS--YSDSAEMLsgnsdlnEKLRE 991
Cdd:TIGR02169 301 --AEIASLERSIAEKERELEDAEeRLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTeeYAELKEEL-------EDLRA 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 992 RLEQAEAERTRAREALrghaaqlsqynqvlASLKSSYDTKKELLNDLQRELQDIGVRAdsgaeERARIRRDELHAQLSNN 1071
Cdd:TIGR02169 372 ELEEVDKEFAETRDEL--------------KDYREKLEKLKREINELKRELDRLQEEL-----QRLSEELADLNAAIAGI 432
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446494780 1072 RSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAgwcavmrmvKDNGVERRLH--RRELAYLSA 1143
Cdd:TIGR02169 433 EAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE---------EYDRVEKELSklQRELAEAEA 497
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
507-680 |
8.20e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 8.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 507 DQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADfcKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQE 586
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLK--QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 587 QEQLQSRIQSLMQRA--------PVWLAAQNSLNQLS-------------EQCGEEFTSSQDVTEYLQQLLEREREAIV- 644
Cdd:COG4942 99 LEAQKEELAELLRALyrlgrqppLALLLSPEDFLDAVrrlqylkylaparREQAEELRADLAELAALRAELEAERAELEa 178
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446494780 645 -------ERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAER 680
Cdd:COG4942 179 llaeleeERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
781-1102 |
1.73e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.83 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 781 AARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELER---ALSNHEN 857
Cdd:COG4717 84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEErleELRELEE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 858 DNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFE 937
Cdd:COG4717 164 ELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 938 QLKE-----------------------------------------DYAYSQQMQRDARQQAFALTEVVQRRA-------- 968
Cdd:COG4717 244 RLKEarlllliaaallallglggsllsliltiagvlflvlgllalLFLLLAREKASLGKEAEELQALPALEEleeeelee 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 969 -----HFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAR-EALRGHAAQLSQYNQV--------LASLKSSYDTKKEL 1034
Cdd:COG4717 324 llaalGLPPDLSPEELLELLDRIEELQELLREAEELEEELQlEELEQEIAALLAEAGVedeeelraALEQAEEYQELKEE 403
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446494780 1035 LNDLQRELQDIgvrADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERD 1102
Cdd:COG4717 404 LEELEEQLEEL---LGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEED 468
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
835-1234 |
2.43e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.50 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 835 EAEIRQLNSRrveLErALSNHENDNQQQriqFEQAKEGVTALNRilpRLNLLAD--DSLADRVDEIRERLDEAQEAARFV 912
Cdd:pfam10174 302 ESELLALQTK---LE-TLTNQNSDCKQH---IEVLKESLTAKEQ---RAAILQTevDALRLRLEEKESFLNKKTKQLQDL 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 913 Q-QFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQR-RAHFSYSDSA-----EMLSGNSDL 985
Cdd:pfam10174 372 TeEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSlQTDSSNTDTAlttleEALSEKERI 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 986 NEKLRERLEQAEAERTRAREALRghaAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIgvrADSGAEERARIRRDELH 1065
Cdd:pfam10174 452 IERLKEQREREDRERLEELESLK---KENKDLKEKVSALQPELTEKESSLIDLKEHASSL---ASSGLKKDSKLKSLEIA 525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1066 AQLSNNRSRR--NQLEKALTFCEAEMDN--LTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYL 1141
Cdd:pfam10174 526 VEQKKEECSKleNQLKKAHNAEEAVRTNpeINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAEL 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1142 SADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQhlrerirqdiirTDDPVEAIEQMEIELSR 1221
Cdd:pfam10174 606 ESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQ------------LEELMGALEKTRQELDA 673
|
410
....*....|...
gi 446494780 1222 LTEELTSREQKLA 1234
Cdd:pfam10174 674 TKARLSSTQQSLA 686
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
551-659 |
2.91e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 42.38 E-value: 2.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 551 DIDELEALHQELEARIASLSDSVSNAREERMA-LRQEQEQLQSRIQSLMQRapvWLAAQNSLNQLSEQCGEEFTSSQDVT 629
Cdd:COG0542 412 ELDELERRLEQLEIEKEALKKEQDEASFERLAeLRDELAELEEELEALKAR---WEAEKELIEEIQELKEELEQRYGKIP 488
|
90 100 110
....*....|....*....|....*....|
gi 446494780 630 EYLQQLLEREREAIVERDEVgarKNAVDEE 659
Cdd:COG0542 489 ELEKELAELEEELAELAPLL---REEVTEE 515
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
826-1113 |
3.42e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 3.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 826 LAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILprlnlladDSLADRVDEIRERLDEA 905
Cdd:COG4942 10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI--------AALARRIRALEQELAAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 906 QEaarfvqqfgnQLAKLEPIVSVLQsdpEQFEQLKEDYA-YSQQMQRDARQQAFALTevvqrrahFSYSDSAEMLSGNSD 984
Cdd:COG4942 82 EA----------ELAELEKEIAELR---AELEAQKEELAeLLRALYRLGRQPPLALL--------LSPEDFLDAVRRLQY 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 985 LNEKLRERLEQAEAERtrarealrghaAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIgvradsgaeERARIRRDEL 1064
Cdd:COG4942 141 LKYLAPARREQAEELR-----------ADLAELAALRAELEAERAELEALLAELEEERAAL---------EALKAERQKL 200
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 446494780 1065 HAQLsnnRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTA 1113
Cdd:COG4942 201 LARL---EKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
|
|
| Golgin_A5 |
pfam09787 |
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ... |
499-665 |
4.00e-03 |
|
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.
Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 40.90 E-value: 4.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 499 RELLREGVDQrhLAEQVQPLRMRLSELE-QRLREQQEAERLLADFCKRqgknfdIDELEALHQELEARIASLSDSVSNAR 577
Cdd:pfam09787 56 RDLLREEIQK--LRGQIQQLRTELQELEaQQQEEAESSREQLQELEEQ------LATERSARREAEAELERLQEELRYLE 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 578 EErmaLRQEQEQLQSRIQSL---MQRapvwLAAQNSLNQLSEqcgeefTSSQDVTEYLQQLLER--EREAIVErdEVGAR 652
Cdd:pfam09787 128 EE---LRRSKATLQSRIKDReaeIEK----LRNQLTSKSQSS------SSQSELENRLHQLTETliQKQTMLE--ALSTE 192
|
170
....*....|...
gi 446494780 653 KNAVDEEIERLSQ 665
Cdd:pfam09787 193 KNSLVLQLERMEQ 205
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
845-1115 |
4.16e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.56 E-value: 4.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 845 RVELERALSNHENDNQQQRIQFEQ--AKEGVTALNRILPRLNLLAD--DSLADRVDEIRERLDEAQEAARFVQQFGNQLA 920
Cdd:PRK02224 175 RLGVERVLSDQRGSLDQLKAQIEEkeEKDLHERLNGLESELAELDEeiERYEEQREQARETRDEADEVLEEHEERREELE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 921 KLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAfaLTEVVQRRAHFSYSD-SAEMLSgnsDLNEKLRERLEQAEAE 999
Cdd:PRK02224 255 TLEAEIEDLRETIAETEREREELAEEVRDLRERLEEL--EEERDDLLAEAGLDDaDAEAVE---ARREELEDRDEELRDR 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1000 RTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRR--DELHAQLSNNRSRRNQ 1077
Cdd:PRK02224 330 LEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEeiEELRERFGDAPVDLGN 409
|
250 260 270
....*....|....*....|....*....|....*...
gi 446494780 1078 LEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKA 1115
Cdd:PRK02224 410 AEDFLEELREERDELREREAELEATLRTARERVEEAEA 447
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
345-673 |
5.23e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 41.26 E-value: 5.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 345 RQQEKIERYEadldelQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLADyQQALDVQQTRAIQynqAIAALN 424
Cdd:pfam17380 288 QQQEKFEKME------QERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAE-QERMAMERERELE---RIRQEE 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 425 RAKELCHLPDLTADCAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQlvvAINGPLARNEAWDVARELLRE 504
Cdd:pfam17380 358 RKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQR---KIQQQKVEMEQIRAEQEEARQ 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 505 GVDQRHLAEQVQPL-RMRLSELEQrlreQQEAERLLADFCKRQGKNFDIDELEALHQELEariaslsdsvsnaREERMAL 583
Cdd:pfam17380 435 REVRRLEEERAREMeRVRLEEQER----QQQVERLRQQEEERKRKKLELEKEKRDRKRAE-------------EQRRKIL 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 584 RQE-QEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQ----CGEEFTSSQDVTEYLQQLLEREREAIVERdevgARKNAVDE 658
Cdd:pfam17380 498 EKElEERKQAMIEEERKRKLLEKEMEERQKAIYEEerrrEAEEERRKQQEMEERRRIQEQMRKATEER----SRLEAMER 573
|
330
....*....|....*
gi 446494780 659 EIERLSQPGGSEDQR 673
Cdd:pfam17380 574 EREMMRQIVESEKAR 588
|
|
| AAA_23 |
pfam13476 |
AAA domain; |
10-51 |
6.80e-03 |
|
AAA domain;
Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 39.40 E-value: 6.80e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 446494780 10 LTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTAL 51
Cdd:pfam13476 1 LTIENFRSFRDQTIDFSKGLTLITGPNGSGKTTILDAIKLAL 42
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
345-1116 |
6.88e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 40.98 E-value: 6.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 345 RQQEKIERYEADLDELQIRLEEQ-NEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQAlDVQQtraiqynqaiaal 423
Cdd:pfam12128 276 SRQEERQETSAELNQLLRTLDDQwKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDA-DIET------------- 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 424 nRAKELCHLPDLTADCAAewletfQAKELEATEkmlsleqkmsmaqTAHSQFEQAYQ-LVVAINGPLARN-EAWDVAREL 501
Cdd:pfam12128 342 -AAADQEQLPSWQSELEN------LEERLKALT-------------GKHQDVTAKYNrRRSKIKEQNNRDiAGIKDKLAK 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 502 LREGVDQRHLAEqvqplRMRLSELEQRLREQQEAERLladfckrqgkNFDIDELealhqELEARIASLS---DSVSNARE 578
Cdd:pfam12128 402 IREARDRQLAVA-----EDDLQALESELREQLEAGKL----------EFNEEEY-----RLKSRLGELKlrlNQATATPE 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 579 ERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQllerereaiverdevgaRKNAVDE 658
Cdd:pfam12128 462 LLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEE-----------------RQSALDE 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 659 EIERLSQPGGSEDQRLNalaerfggvllseiyddvslEDAPYFSalygpsrhaivvpdlsqvtEHLEGLTDcPEDLYLIE 738
Cdd:pfam12128 525 LELQLFPQAGTLLHFLR--------------------KEAPDWE-------------------QSIGKVIS-PELLHRTD 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 739 GDPQSFDDSVFSvdelekavvvkiadrqwrysrfpEVPLFGRAARESRIE--SLHAEREVLSERFATLSFDVQKTQRLHQ 816
Cdd:pfam12128 565 LDPEVWDGSVGG-----------------------ELNLYGVKLDLKRIDvpEWAASEEELRERLDKAEEALQSAREKQA 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 817 AfsrfIGSHLAVAFesdpeaeiRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADrVD 896
Cdd:pfam12128 622 A----AEEQLVQAN--------GELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNS-LE 688
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 897 EIRERLDEAQEAarFVQQFGNQL-----AKLEPIVSVLQSDPEQFEQLKEDYAySQQMQRDARQQAFaltEVVQRRAHFS 971
Cdd:pfam12128 689 AQLKQLDKKHQA--WLEEQKEQKreartEKQAYWQVVEGALDAQLALLKAAIA-ARRSGAKAELKAL---ETWYKRDLAS 762
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 972 YSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTK-KELLNDLQRELQDIGVR-- 1048
Cdd:pfam12128 763 LGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAiSELQQQLARLIADTKLRra 842
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 1049 ---ADSGAEERARIRRDELHAQLSNNRSR---------RNQLEKALTFCEAEMDNLTRKLRKLERD---YFEMREQVVTA 1113
Cdd:pfam12128 843 kleMERKASEKQQVRLSENLRGLRCEMSKlatlkedanSEQAQGSIGERLAQLEDLKLKRDYLSESvkkYVEHFKNVIAD 922
|
...
gi 446494780 1114 KAG 1116
Cdd:pfam12128 923 HSG 925
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
6-51 |
7.40e-03 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 39.61 E-value: 7.40e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446494780 6 KFRSLTLINWNGFF-ARTFDLDELVTTLSGGNGAGKSTTMAAFVTAL 51
Cdd:COG0419 1 KLLRLRLENFRSYRdTETIDFDDGLNLIVGPNGAGKSTILEAIRYAL 47
|
|
| mS26 |
cd23644 |
mS26 domain protein found in trypanosomal mitochondrial ribosomes; mS26 protein is a ... |
197-359 |
9.06e-03 |
|
mS26 domain protein found in trypanosomal mitochondrial ribosomes; mS26 protein is a mitochondrial protein found in Trypanosoma, but its function has not yet been fully characterized. It is known to be a component of the small subunits of the Trypanosoma mitochondrial ribosome (Tb-mt-SSUs) and interacts with the C-terminal domain (CTD) of initiation factor IF-3 to form a complex called Tb-mt-SSU/IF-3. This complex may play a role in the maturation of the mitochondrial ribosome.
Pssm-ID: 467879 Cd Length: 295 Bit Score: 40.07 E-value: 9.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 197 FYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRE--NRMTLEAIRVtQSDRDLFKHLISEATNYVAADY 274
Cdd:cd23644 6 YYNLPSKSEHGRKMTGFLTPYRHWMWKQNELWRNVHEAQFEHLRRvyKRQWLESFRV-NADEYIYKYNITKAAQLAQWEC 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494780 275 MRHANERrvhldKALEfRRELHTSRQQLAAeqyKHVDMARELAEHNgaegdLEADYQAASDHL---NLVQTaLRQQEKIE 351
Cdd:cd23644 85 EMKEQEK-----KRIE-ARQMMDGRQALKK---KHLDLLREFHERQ-----FFFWYERASERLqnmNLINY-VPHAQLRE 149
|
....*...
gi 446494780 352 RYEADLDE 359
Cdd:cd23644 150 HIDKELDK 157
|
|
| |
