|
Name |
Accession |
Description |
Interval |
E-value |
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
2-1471 |
0e+00 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 2322.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 2 IERGKYQSLTMINWNGFFARTFDIDNLVTTLSGGNGAGKSTTMAAFITALIPDQSLLHFRNTTEAGSSQASRDKGLYGKL 81
Cdd:COG3096 1 IERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 82 QAGACYAALDVVNSRNQRLLFAVKLQQVAGRDKKVDIKPFLIQGLPSHVKPTDVLVETVSDKHARVRQINEVKDAVGQIE 161
Cdd:COG3096 81 KPGVCYAALDVVNSRGQRLLVGVRLQQVAGRDKKVDIKPFIIQGLPEDVKPTDLLTETLDGRQARVLPLNELKEKAEELE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 162 GAHFKSFPSIVDYHAQMFEFGVIPKKLRNSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPQNGGVKKAFQDMESALRE 241
Cdd:COG3096 161 GVQFKQFNSITDYHAFMFDLGVTPKRLRSSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 242 NRMTLEAIKTTQADRDLFKHLITESTNYVAADYMRHANDRRNKVGQTLVLRGELFSSRETLIEQNSLLNRVHEELELLVE 321
Cdd:COG3096 241 NRMTLEAIRVTQSDRDLFKHLITEATNYVAADYMRHANERRELSERALELRRELFGARRQLAEEQYRLVEMARELEELSA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 322 QESALEQDYQGASDHLQLVQNALRQQEKIERYQEDLEELNFRLEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLAD 401
Cdd:COG3096 321 RESDLEQDYQAASDHLNLVQTALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLAD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 402 YQQALDVQQTRALQYQQAVQALDKARRLLDKSELTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFEL 481
Cdd:COG3096 401 YQQALDVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYEL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 482 VKRVLGEVARSEAAKQAQQVIRQAREAQNVVQNEAQWQAQQRDLERQLEQQRSVRELATQYHKQHRVVLDDAATVELERE 561
Cdd:COG3096 481 VCKIAGEVERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLA 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 562 RHSALLEELETEQENCREQRGQLRHQEQELQTQIARFESIAPAWIKANDALETLREQSGAELADSQSVMAHMQQVLELEK 641
Cdd:COG3096 561 ELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLERER 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 642 AQSMAKDKLAERRTKLDSEIERLASPGGSNDPRLKGLADTLGGVLLSEIYDDITIDDAPYFSAMYGPARHAIVVSDLSGI 721
Cdd:COG3096 641 EATVERDELAARKQALESQIERLSQPGGAEDPRLLALAERLGGVLLSEIYDDVTLEDAPYFSALYGPARHAIVVPDLSAV 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 722 KEKLVELDDCPEDLYLIEGDVDAFDDSSFNAEELEGAVCVQLNQRQMRYSRFPAIPLFGRAAREQRLELLREERDDVVEQ 801
Cdd:COG3096 721 KEQLAGLEDCPEDLYLIEGDPDSFDDSVFDAEELEDAVVVKLSDRQWRYSRFPEVPLFGRAAREKRLEELRAERDELAEQ 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 802 HAKASFDSQKLQRLYASFNQFVAMHLQVAFDADPEQALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAALDKLA 881
Cdd:COG3096 801 YAKASFDVQKLQRLHQAFSQFVGGHLAVAFAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 882 PQMGLLDEETLEARYHELEEKLQQLSEAKAFIAAHGRTISELEKVAAVLDADPEQFDALEQQYQQADQALQQLKAQIFAL 961
Cdd:COG3096 881 PQANLLADETLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFAL 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 962 SDLLERRHHFAYSDSVDLLNQSSELSEQLKAKLVQAESERTRSREELKQAQAQLSQYNQLLASLKSSHQAKLETVQEFKQ 1041
Cdd:COG3096 961 SEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQ 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1042 ELQEFGVHADEGAIERAQRRRDELQERLHTSRSRKSEYERTITSTELEMKALVKRMKKVEKDYQDLRTFVVNAKAGWCSV 1121
Cdd:COG3096 1041 ELEELGVQADAEAEERARIRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKAGWCAV 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1122 LRLARQNDVERRLHKRELAYLSADELRSMSDKSLGALRLAVANNEDLRDALRQSEDNSRPERKVLFYIAVYQHLRERIRQ 1201
Cdd:COG3096 1121 LRLARDNDVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDALRLSEDPRRPERKVQFYIAVYQHLRERIRQ 1200
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1202 DIIRTDDPVEAIEEMEVELARLTEELTQREQRLAISSDSVASIIRKTIQREQNRIRMLNQGLSNISFGQVNGVRLNVKVR 1281
Cdd:COG3096 1201 DIIRTDDPVEAIEQMEIELARLTEELTSREQKLAISSESVANIIRKTIQREQNRIRMLNQGLQNVSFGQVKGVRLNVNIR 1280
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1282 ESHEILLAGLSEQQAQHKDLFESARYTFSEAMAKLFQRVNPHIDMGQRSPQVLGEELLDYRNYLELSVEVNRGSDGWLQA 1361
Cdd:COG3096 1281 ETHAQLLDALSEQQEQHQDLFFSNRLTFSEALAKLYQRLNPHIDMGQRSPQTIGEELLDYRNYLELEVEVNRGADGWLRA 1360
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1362 ESGALSTGEAIGTGQSILLMVVQSWEEESRRLRSKDIVPCRLLFLDEAARLDAKSIATLFELCERLDMQLLIAAPENISP 1441
Cdd:COG3096 1361 ESGALSTGEAIGTGMSILLMVVQSWEEESRRLRGKDISPCRLLFLDEAARLDAKSIATLFELCERLDMQLLIAAPENISP 1440
|
1450 1460 1470
....*....|....*....|....*....|
gi 446494934 1442 EKGTTYKLVRKVFKDHEHVHVVGLRGFAQT 1471
Cdd:COG3096 1441 EKGTTYKLVRKVFNNQEHVHVVGLRGFGQE 1470
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1-1486 |
0e+00 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 2257.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1 MIERGKYQSLTMINWNGFFARTFDIDNLVTTLSGGNGAGKSTTMAAFITALIPDQSLLHFRNTTEAGSSQASRDKGLYGK 80
Cdd:PRK04863 1 MIERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 81 LQAGACYAALDVVNSRNQRLLFAVKLQQVAGRDKKVDIKPFLIQGLPSHVKPTDVLVETVSDKHARVRQINEVKDAVGQI 160
Cdd:PRK04863 81 LKAGVCYAALDVVNSRGQRVLVGVRLQQVAGRDRKVDIKPFAIQGLPDSVQPTDLLTETVNERQARVLTLNELKDKAAAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 161 EGAHFKSFPSIVDYHAQMFEFGVIPKKLRNSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPQNGGVKKAFQDMESALR 240
Cdd:PRK04863 161 EGVQFKQFNSITDYHSLMFDLGIIPRRLRSSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 241 ENRMTLEAIKTTQADRDLFKHLITESTNYVAADYMRHANDRRNKVGQTLVLRGELFSSRETLIEQNSLLNRVHEELELLV 320
Cdd:PRK04863 241 ENRMTLEAIRVTQSDRDLFKHLITESTNYVAADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 321 EQESALEQDYQGASDHLQLVQNALRQQEKIERYQEDLEELNFRLEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLA 400
Cdd:PRK04863 321 EAESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 401 DYQQALDVQQTRALQYQQAVQALDKARRLLDKSELTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFE 480
Cdd:PRK04863 401 DYQQALDVQQTRAIQYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQ 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 481 LVKRVLGEVARSEAAKQAQQVIRQAREAQNVVQNEAQWQAQQRDLERQLEQQRSVRELATQYHKQHRVVLDDAATVELER 560
Cdd:PRK04863 481 LVRKIAGEVSRSEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQ 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 561 ERHSALLEELETEQENCREQRGQLRHQEQELQTQIARFESIAPAWIKANDALETLREQSGAELADSQSVMAHMQQVLELE 640
Cdd:PRK04863 561 EELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 641 KAQSMAKDKLAERRTKLDSEIERLASPGGSNDPRLKGLADTLGGVLLSEIYDDITIDDAPYFSAMYGPARHAIVVSDLSG 720
Cdd:PRK04863 641 RELTVERDELAARKQALDEEIERLSQPGGSEDPRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPARHAIVVPDLSD 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 721 IKEKLVELDDCPEDLYLIEGDVDAFDDSSFNAEELEGAVCVQLNQRQMRYSRFPAIPLFGRAAREQRLELLREERDDVVE 800
Cdd:PRK04863 721 AAEQLAGLEDCPEDLYLIEGDPDSFDDSVFSVEELEKAVVVKIADRQWRYSRFPEVPLFGRAAREKRIEQLRAEREELAE 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 801 QHAKASFDSQKLQRLYASFNQFVAMHLQVAFDADPEQALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAALDKL 880
Cdd:PRK04863 801 RYATLSFDVQKLQRLHQAFSRFIGSHLAVAFEADPEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 881 APQMGLLDEETLEARYHELEEKLQQLSEAKAFIAAHGRTISELEKVAAVLDADPEQFDALEQQYQQADQALQQLKAQIFA 960
Cdd:PRK04863 881 LPRLNLLADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFA 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 961 LSDLLERRHHFAYSDSVDLLNQSSELSEQLKAKLVQAESERTRSREELKQAQAQLSQYNQLLASLKSSHQAKLETVQEFK 1040
Cdd:PRK04863 961 LTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELK 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1041 QELQEFGVHADEGAIERAQRRRDELQERLHTSRSRKSEYERTITSTELEMKALVKRMKKVEKDYQDLRTFVVNAKAGWCS 1120
Cdd:PRK04863 1041 QELQDLGVPADSGAEERARARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKAGWCA 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1121 VLRLARQNDVERRLHKRELAYLSADELRSMSDKSLGALRLAVANNEDLRDALRQSEDNSRPERKVLFYIAVYQHLRERIR 1200
Cdd:PRK04863 1121 VLRLVKDNGVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKVQFYIAVYQHLRERIR 1200
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1201 QDIIRTDDPVEAIEEMEVELARLTEELTQREQRLAISSDSVASIIRKTIQREQNRIRMLNQGLSNISFGQVNGVRLNVKV 1280
Cdd:PRK04863 1201 QDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSESVANIIRKTIQREQNRIRMLNQGLQNISFGQVKSVRLNVNV 1280
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1281 RESHEILLAGLSEQQAQHKDLFESARYTFSEAMAKLFQRVNPHIDMGQRSPQVLGEELLDYRNYLELSVEVNRGSDGWLQ 1360
Cdd:PRK04863 1281 RETHAMLLDALSEQQEQHQDLFNSARLTFSEALAKLYQRLNPHIDMGQRTPQTIGEELLDYRNYLELEVEVNRGADGWLR 1360
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1361 AESGALSTGEAIGTGQSILLMVVQSWEEESRRLRSKDIVPCRLLFLDEAARLDAKSIATLFELCERLDMQLLIAAPENIS 1440
Cdd:PRK04863 1361 AESGALSTGEAIGTGMSILVMVVQSWEEESRRLRGKDISPCRLLFLDEAARLDAKSIATLFELCERLDMQLLIAAPENIS 1440
|
1450 1460 1470 1480
....*....|....*....|....*....|....*....|....*.
gi 446494934 1441 PEKGTTYKLVRKVFKDHEHVHVVGLRGFAQTEKPKTAEQKFAEELA 1486
Cdd:PRK04863 1441 PEKGTTYKLVRKVFNNREHVHVVGLRGFAQLLPDTLPGQDEAESGA 1486
|
|
| MukB |
pfam04310 |
MukB N-terminal; This family represents the N-terminal region of MukB, one of a group of ... |
2-227 |
9.24e-142 |
|
MukB N-terminal; This family represents the N-terminal region of MukB, one of a group of bacterial proteins essential for the movement of nucleoids from mid-cell towards the cell quarters (i.e. chromosome partitioning). The structure of the N-terminal domain consists of an antiparallel six-stranded beta sheet surrounded by one helix on one side and by five helices on the other side. It contains an exposed Walker A loop in an unexpected helix-loop-helix motif (in other proteins, Walker A motifs generally adopt a P loop conformation as part of a strand-loop-helix motif embedded in a conserved topology of alternating helices and (parallel) beta strands).
Pssm-ID: 427856 [Multi-domain] Cd Length: 226 Bit Score: 433.06 E-value: 9.24e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 2 IERGKYQSLTMINWNGFFARTFDIDNLVTTLSGGNGAGKSTTMAAFITALIPDQSLLHFRNTTEAGSSQASRDKGLYGKL 81
Cdd:pfam04310 1 IERGKFQSLTMINWNGFFARTFDLDQLVTTLSGGNGAGKSTTMAAFITALIPDLSLLHFRNTTEAGSTSGSRDKGLYGKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 82 QAGACYAALDVVNSRNQRLLFAVKLQQVAGRDKKVDIKPFLIQGLPSHVKPTDVLVETVSDKHARVRQINEVKDAVGQIE 161
Cdd:pfam04310 81 QAGHCYSAIDVANSRGQRLWFGVHLQQVAGRDRKVDITPFAIQGLPEDVQPTDVLLERLDDGHARVRSLNELKDAAAELG 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446494934 162 GAHFKSFPSIVDYHAQMFEFGVIPKKLRNSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPQNGG 227
Cdd:pfam04310 161 GARFKQFNSITDYHNFMFDMGVTPKKLRDQRDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSG 226
|
|
| MukB_hinge |
pfam16330 |
MukB hinge domain; The hinge domain of chromosome partition protein MukB is responsible for ... |
645-811 |
1.11e-77 |
|
MukB hinge domain; The hinge domain of chromosome partition protein MukB is responsible for dimerization and is also involved in protein-DNA interactions and conformational flexibility.
Pssm-ID: 435281 [Multi-domain] Cd Length: 167 Bit Score: 253.80 E-value: 1.11e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 645 MAKDKLAERRTKLDSEIERLASPGGSNDPRLKGLADTLGGVLLSEIYDDITIDDAPYFSAMYGPARHAIVVSDLSGIKEK 724
Cdd:pfam16330 1 QERDELAARKERLEKEIERLLQPGGSEDPRLPRLAERLGGVLLSEIYDDISLEDAPYFSALYGPARHAIVVPDLSDAADK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 725 LVELDDCPEDLYLIEGDVDAFDDSSFNAEELEGAVCVQLNQRQMRYSRFPAIPLFGRAAREQRLELLREERDDVVEQHAK 804
Cdd:pfam16330 81 LNGLEDCPDDLYLIEGDPDSFDESAFSAEELEDAVLVHDSDRQLRYSRFPEVPLFGRAAREKRLEALRAEREELAERYAK 160
|
....*..
gi 446494934 805 ASFDSQK 811
Cdd:pfam16330 161 LAFDVQK 167
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
345-1111 |
6.65e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 87.03 E-value: 6.65e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 345 RQQEKIERYQE---------------DLEELNFRLEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLADYQQALDVQ 409
Cdd:TIGR02168 207 RQAEKAERYKElkaelrelelallvlRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 410 QTRALQYQQAVQALDKARRLLDKS----ELTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFELVKRV 485
Cdd:TIGR02168 287 QKELYALANEISRLEQQKQILRERlanlERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 486 LGEVARSEAAKQaQQVIRQAREAQNVVQNEAQWQAQQRDLERQLEQQRSVRELATQYHKQHRVVLDdaatvELERERHSA 565
Cdd:TIGR02168 367 LEELESRLEELE-EQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE-----EAELKELQA 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 566 LLEELETEQENCREQRGQLRHQEQELQTQIARFESiapawikANDALETLREQSGAELADSQSVMAHMQQVLELEKAQSM 645
Cdd:TIGR02168 441 ELEELEEELEELQEELERLEEALEELREELEEAEQ-------ALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 646 AKDKLA----------ERRTKLDSEIErLASPGGSNDPRLKGLADTLGGV--LLSEIYDDITIDDAPYFSAMYGPARHAI 713
Cdd:TIGR02168 514 NQSGLSgilgvlseliSVDEGYEAAIE-AALGGRLQAVVVENLNAAKKAIafLKQNELGRVTFLPLDSIKGTEIQGNDRE 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 714 VVSDLSGIKEKLVELDDCPEDLyliEGDVDAFDDSSFNAEELEGAvcvqLNQRQMRYSRFPAIPLFG------------- 780
Cdd:TIGR02168 593 ILKNIEGFLGVAKDLVKFDPKL---RKALSYLLGGVLVVDDLDNA----LELAKKLRPGYRIVTLDGdlvrpggvitggs 665
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 781 ------RAAREQRLELLREERDDVVEQHAKAsfdSQKLQRLYASFNQFvamhlqvafdadpEQALATARDKRNQLLRSIS 854
Cdd:TIGR02168 666 aktnssILERRREIEELEEKIEELEEKIAEL---EKALAELRKELEEL-------------EEELEQLRKELEELSRQIS 729
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 855 EFEAQEQQLRSQLQASKQALAALDKlapqmgllDEETLEARYHELEEKLQQLSEAKAfiaahgRTISELEKVAAVLDADP 934
Cdd:TIGR02168 730 ALRKDLARLEAEVEQLEERIAQLSK--------ELTELEAEIEELEERLEEAEEELA------EAEAEIEELEAQIEQLK 795
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 935 EQFDALEQQYQQADQALQQLKAQIFALSDLLErRHHFAYSDSVDLLNQSSELSEQLKAKLVQAESERTRSREELKQAQAQ 1014
Cdd:TIGR02168 796 EELKALREALDELRAELTLLNEEAANLRERLE-SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1015 LsqynQLLASLKSSHQAKLETVQEFKQELQEfGVHADEGAIERAQRRRDELQERLHTSRSRKSEYERTITST-------- 1086
Cdd:TIGR02168 875 L----EALLNERASLEEALALLRSELEELSE-ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLqerlseey 949
|
810 820
....*....|....*....|....*
gi 446494934 1087 ELEMKALVKRMKKVEKDYQDLRTFV 1111
Cdd:TIGR02168 950 SLTLEEAEALENKIEDDEEEARRRL 974
|
|
| SbcC_Walker_B |
pfam13558 |
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ... |
1336-1426 |
8.36e-15 |
|
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.
Pssm-ID: 463921 [Multi-domain] Cd Length: 90 Bit Score: 71.11 E-value: 8.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1336 EELLDYRNYLELSVEVNR--GSDGWLQAESGALSTGEAIGTGQSILL--MVVQSWEEESRRLRskdivpCRLLFLDEA-A 1410
Cdd:pfam13558 1 ARVLDYRNWLSFEVEVRDedGSEVETYRRSGGLSGGEKQLLAYLPLAaaLAAQYGSAEGRPPA------PRLVFLDEAfA 74
|
90
....*....|....*.
gi 446494934 1411 RLDAKSIATLFELCER 1426
Cdd:pfam13558 75 KLDEENIRTALELLRA 90
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
988-1436 |
3.80e-14 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 78.03 E-value: 3.80e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 988 EQLKAKLVQAESERTRSREELKQAQAQLSQYNQLLASLKS-----SHQAKLETVQEFKQELQefgvhADEGAIERAQRRR 1062
Cdd:COG4913 620 AELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeidvaSAEREIAELEAELERLD-----ASSDDLAALEEQL 694
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1063 DELQERLHTSRSRKSEYERTITSTELEMKALVKRMKKVEKDYQDLRTFVvnakagwcsvlRLARQNDVERRLhKRELAYL 1142
Cdd:COG4913 695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLA-----------RLELRALLEERF-AAALGDA 762
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1143 SADELRSMSDKSLGALRLAVAN-NEDLRDALRQsednsrperkvlfYIAVYqhlreriRQDIIRTDDPVEAIEEMEVELA 1221
Cdd:COG4913 763 VERELRENLEERIDALRARLNRaEEELERAMRA-------------FNREW-------PAETADLDADLESLPEYLALLD 822
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1222 RLTEE-LTQREQRL--AISSDSVASI------IRKTIQREQNRIRMLNQGLSNISFGQvnGVRLNVKVRESHeilLAGLS 1292
Cdd:COG4913 823 RLEEDgLPEYEERFkeLLNENSIEFVadllskLRRAIREIKERIDPLNDSLKRIPFGP--GRYLRLEARPRP---DPEVR 897
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1293 EQQAQHKDLFESARYTFSEAMAKLFQRVNPHIDM-GQRSPQVLG---EELLDYRNYLELSVEVNRGSDG---WLQAESGA 1365
Cdd:COG4913 898 EFRQELRAVTSGASLFDEELSEARFAALKRLIERlRSEEEESDRrwrARVLDVRNHLEFDAEEIDREDGeevETYSSSGG 977
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446494934 1366 LSTGE-------AIGtgqSILLMVVQSWEEESRRLrskdivpcRLLFLDEA-ARLDAKSIATLFELCERLDMQLLIAAP 1436
Cdd:COG4913 978 KSGGEkqklayfILA---AALAYQLGLEGRGRPSF--------RTVVLDEAfSKMDEEFARRALRLFKELGLQLLIATP 1045
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
395-936 |
4.98e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.20 E-value: 4.98e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 395 LKSQLadyqQALDVQQTRALQYQQ------------AVQALDKARRLLDKSELTAESAQALATQLKAEQETRTSELLALK 462
Cdd:COG1196 198 LERQL----EPLERQAEKAERYRElkeelkeleaelLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 463 HKLDMSSAAAQQFNHAFELVKRvlgEVARSEAAKQAQQvIRQAREAQNVVQNEAQWQAQQRDLERQLEQQRSVRELATQY 542
Cdd:COG1196 274 LELEELELELEEAQAEEYELLA---ELARLEQDIARLE-ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 543 HKQHRVVLDDAATVELERERHSALLEELETEQENCREQRGQLRHQEQELQTQIARFESiapawiKANDALETLREQSGAE 622
Cdd:COG1196 350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE------AEEALLERLERLEEEL 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 623 LADSQSVMAHMQQVLELEKAQSMAKDKLAERRTKLDSEIERLASPGGSNDPRLKGLADTLGGVLLSEIYDDITIDDAPYF 702
Cdd:COG1196 424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 703 SAMYGPARHAIVVSDLSGIKEKLVELDDCPEDLYLIEGDVDAFDDSSFNAEELEGAVCVQLNQRQMRYSRFPAIPLfgra 782
Cdd:COG1196 504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL---- 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 783 AREQRLELLREERDDVVEQHAKASFDSQKLQRLYASFNQFVAMHLQVAFDADPEQALATARdKRNQLLRSISEFEAQEQQ 862
Cdd:COG1196 580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV-TLAGRLREVTLEGEGGSA 658
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446494934 863 LRSQLQASKQALAALDKLAPQMGLLDEETLEARYHELEEKLQQLSEAKAFIAAHGRTISELEKVAAVLDADPEQ 936
Cdd:COG1196 659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
270-911 |
5.03e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.20 E-value: 5.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 270 VAADYMRHANDRRNKVGQTLVLRGELFSSRETLIEQNslLNRVHEELELLVEQESALEQDYQGASDHLQlvqnalRQQEK 349
Cdd:COG1196 211 KAERYRELKEELKELEAELLLLKLRELEAELEELEAE--LEELEAELEELEAELAELEAELEELRLELE------ELELE 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 350 IERYQEDLEELNFRLEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTRALQYQQAVQALDKARrl 429
Cdd:COG1196 283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL-- 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 430 ldkseltAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFELVKRVLGEVARSEAAKQAQQVIRQAREAQ 509
Cdd:COG1196 361 -------AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 510 NVVQNEAQWQAQQRDLERQLEQQRSVRELATQYHKQHRVVLDDAATVELERERHSALLEELETEQENCREQ---RGQLRH 586
Cdd:COG1196 434 EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflEGVKAA 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 587 QEQELQTQIARFESIAPAWIKANDALEtlreqsgAELADSQSVMAHMQQVLELEKAQSMAKDKLAERRTKLDSEIERLAS 666
Cdd:COG1196 514 LLLAGLRGLAGAVAVLIGVEAAYEAAL-------EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARA 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 667 PGGSNDPRLKGLADTLGgvllseIYDDITIDDAPYFSAMYGPARHAIVVSDLSGIKEKLVELDdcpEDLYLIEGDVDAFD 746
Cdd:COG1196 587 ALAAALARGAIGAAVDL------VASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLA---GRLREVTLEGEGGS 657
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 747 DSSFNAEELEGAVCVQLNQRQMRYSRFpaiplfgRAAREQRLELLREERDDVVEQHAKASFDSQKLQRLYASFNQfvAMH 826
Cdd:COG1196 658 AGGSLTGGSRRELLAALLEAEAELEEL-------AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA--LEE 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 827 LQVAFDADPEQALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAALDK---LApqmglLDE-ETLEARYHELEEK 902
Cdd:COG1196 729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPvnlLA-----IEEyEELEERYDFLSEQ 803
|
....*....
gi 446494934 903 LQQLSEAKA 911
Cdd:COG1196 804 REDLEEARE 812
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
345-961 |
1.02e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 73.05 E-value: 1.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 345 RQQEKIERYQEDLEELN-FRLEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTRALQYQQAVQAL 423
Cdd:COG1196 207 RQAEKAERYRELKEELKeLEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 424 DKARRLLDKSELTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFELVKRVLGEVARSEAAKQAQQVIR 503
Cdd:COG1196 287 QAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEA 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 504 QAREAQNVVQNEAQWQAQQRDLERQLEQQRSVRELATQYHKQHRVVLDDAATVELERERHSALLEELETEQENCREQRGQ 583
Cdd:COG1196 367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 584 LRHQEQELQTQIArfesiapawikandALETLREQSGAELAdsqsvmahmQQVLELEKAQSMAKDKLAERRTKLDSEIER 663
Cdd:COG1196 447 AAEEEAELEEEEE--------------ALLELLAELLEEAA---------LLEAALAELLEELAEAAARLLLLLEAEADY 503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 664 LASPGGSNDPRLKGLADTLGGVLLSEIYDDITIDDAPYFSAmyGPARHAIVVSDLSGIKEKLVELDDcpedlyLIEGDVD 743
Cdd:COG1196 504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKA------AKAGRAT 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 744 AFDDSSFNAEELEGAVcvQLNQRQMRYSRFPAIPLFGRAAREQRLELLREERDDVVEQHAKASFDSQKLQRLYAsfnqFV 823
Cdd:COG1196 576 FLPLDKIRARAALAAA--LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR----EV 649
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 824 AMHLQVAFDAdPEQALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAALDKLAPQMGLLDEETLEARYHELEEKL 903
Cdd:COG1196 650 TLEGEGGSAG-GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 446494934 904 QQLSEAKAFIAAHGRTISELEKVAAVLDADPEQFDALEQQYQQAdqalqqlKAQIFAL 961
Cdd:COG1196 729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL-------EREIEAL 779
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
389-1065 |
2.29e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.28 E-value: 2.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 389 EEEVDSLKSQLADYQQALDVQQT-RALQYQQAVQALDKARRLLDKSELTAESAQALATQLKAEQETRTSELLALKHKLDM 467
Cdd:COG1196 199 ERQLEPLERQAEKAERYRELKEElKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 468 SSAAAQQFNHAFELVKRvlgEVARSEAAKQAQQvIRQAREAQNVVQNEAQWQAQQRDLERQLEQQRSVRELATQYHKQHR 547
Cdd:COG1196 279 LELELEEAQAEEYELLA---ELARLEQDIARLE-ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 548 VVLDDAATVELERERHSALLEELETEQENCREQRGQLRHQEQELQTQIARFESiapawiKANDALETLREQSGAELADSQ 627
Cdd:COG1196 355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE------AEEALLERLERLEEELEELEE 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 628 SVMAHMQQVLELEKAQSMAKDKLAERRTKLDSEIERLASPGGSNDPRLKGLADTLGGVLLSEIYDDITIDDAPYFSAMYG 707
Cdd:COG1196 429 ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 708 PARHAIVVSDLSGIKEKLVELDDCPEDLYLIegdvdafddssfnAEELEGAVCVQLNQRQmrysrfpaiplfgRAAREQR 787
Cdd:COG1196 509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAA-------------LEAALAAALQNIVVED-------------DEVAAAA 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 788 LELLREERDdvveqhAKASFdsqklqrlyasfnqfvamhLQVAFDADPEQALATARDKRNQLLRSISEFEAQEQQLRSQL 867
Cdd:COG1196 563 IEYLKAAKA------GRATF-------------------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 868 QASKQALAALDKLAPQMGLLDEETLEARYHELEEKLQQLSEAKAFIAAHGRTISELEKVAAVLDAdpeqfdaleqqyqqa 947
Cdd:COG1196 618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE--------------- 682
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 948 dqalqqlkaqifalsdLLERRHHFAYSDSVDLLNQSSELSEQLKAKLVQAESERTRSREELKQAQAQLSQYNQLLASlks 1027
Cdd:COG1196 683 ----------------ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE--- 743
|
650 660 670
....*....|....*....|....*....|....*...
gi 446494934 1028 shQAKLETVQEFKQELQEFGVHADEGAIERAQRRRDEL 1065
Cdd:COG1196 744 --EEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
348-1116 |
2.94e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 72.02 E-value: 2.94e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 348 EKIERYQEDLEELNFRLEEQMMVVEEANERVMQ-AEERAiiSEEEVDSLKSQLADYQQALdvqqtRALQYQQAVQALDKA 426
Cdd:TIGR02169 170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERlRRERE--KAERYQALLKEKREYEGYE-----LLKEKEALERQKEAI 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 427 RRLLDKSELTAESAQALATQLKAEQETRTSELLALKHKL-DMSSAAAQQFNHAFELVKRVLGEVARSEAAKQAQQVIRQA 505
Cdd:TIGR02169 243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 506 REAQNVVQNEAQwQAQQRDLERQLEQQRSVRELATQYHKQHRVVLDD--------AATVELERERHSALLEELETEQENC 577
Cdd:TIGR02169 323 RLAKLEAEIDKL-LAEIEELEREIEEERKRRDKLTEEYAELKEELEDlraeleevDKEFAETRDELKDYREKLEKLKREI 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 578 RE-QRGQLRHQE--QELQTQIARFESIAPAWIKANDALETLREQSGAELADSQSVMAHMQQVLELEKAQSMAK----DKL 650
Cdd:TIGR02169 402 NElKRELDRLQEelQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLkeeyDRV 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 651 AERRTKLDSEIERLASPGGSNDPRLKG-------LADTLGGVlLSEIYDDITIDDApYFSAM---YGPARHAIVVSD--- 717
Cdd:TIGR02169 482 EKELSKLQRELAEAEAQARASEERVRGgraveevLKASIQGV-HGTVAQLGSVGER-YATAIevaAGNRLNNVVVEDdav 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 718 --------------------LSGIKEKLVELDDCPEDLYL-IEGDVDAFDDSSFNA-----------EELEGAvcvqlnQ 765
Cdd:TIGR02169 560 akeaiellkrrkagratflpLNKMRDERRDLSILSEDGVIgFAVDLVEFDPKYEPAfkyvfgdtlvvEDIEAA------R 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 766 RQMRYSRF---------PAIPLFGRAAREQRLELL-REERDDVVEQHAkasfDSQKLQRLYASFNQFVamhlqvafdADP 835
Cdd:TIGR02169 634 RLMGKYRMvtlegelfeKSGAMTGGSRAPRGGILFsRSEPAELQRLRE----RLEGLKRELSSLQSEL---------RRI 700
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 836 EQALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAALdklapqmglldEETLEARYHELEEKLQQLSEAKAFIAA 915
Cdd:TIGR02169 701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEL-----------EEDLSSLEQEIENVKSELKELEARIEE 769
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 916 HGRTISELEKVAAVLDAD--PEQFDALEQQYQQADQALQQLKAQIFALSDLLERRH---HFAYSDSVDLLNQSSELSEQL 990
Cdd:TIGR02169 770 LEEDLHKLEEALNDLEARlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTlekEYLEKEIQELQEQRIDLKEQI 849
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 991 KAKLVQAESERTRSRE---ELKQAQAQLSQYNQLLASLKS---SHQAKLETVQEFKQELqefgvhadEGAIERAQRRRDE 1064
Cdd:TIGR02169 850 KSIEKEIENLNGKKEEleeELEELEAALRDLESRLGDLKKerdELEAQLRELERKIEEL--------EAQIEKKRKRLSE 921
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*...
gi 446494934 1065 LQERLHTSRSRKSEYERT------ITSTELEMKALVKRMKKVEKDYQDLRTfvVNAKA 1116
Cdd:TIGR02169 922 LKAKLEALEEELSEIEDPkgedeeIPEEELSLEDVQAELQRVEEEIRALEP--VNMLA 977
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
345-1087 |
1.03e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.55 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 345 RQQEKIERYQEDLEELNFRLEEQMMVVEEANERVMQ-AEERAIISEEEVDSLKSQLADYQQALDVQQTRAlqyQQAVQAL 423
Cdd:TIGR02169 248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKEREL---EDAEERL 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 424 DKARRLLDKSELTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFELVKrvlgevarsEAAKQAQQVIR 503
Cdd:TIGR02169 325 AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR---------DELKDYREKLE 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 504 QAREAQNVVQ-NEAQWQAQQRDLERQLEQQRSVRELATQYHKQHRVVLDDAA----TVELERERHSALLEELETEQENCR 578
Cdd:TIGR02169 396 KLKREINELKrELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAleikKQEWKLEQLAADLSKYEQELYDLK 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 579 EQRGQLRHQEQELQTQIARFESIAPAWIKA---NDALETLREQSG----AELADSQSVMAHMQQVLEL------------ 639
Cdd:TIGR02169 476 EEYDRVEKELSKLQRELAEAEAQARASEERvrgGRAVEEVLKASIqgvhGTVAQLGSVGERYATAIEVaagnrlnnvvve 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 640 -----EKAQSMAKDKLAERRTKLD-SEIERLASPGGSndPRLKGLADTLggvllseiYDDITIDDApYFSAMYGPARHAI 713
Cdd:TIGR02169 556 ddavaKEAIELLKRRKAGRATFLPlNKMRDERRDLSI--LSEDGVIGFA--------VDLVEFDPK-YEPAFKYVFGDTL 624
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 714 VVSDLS-----GIKEKLVELD-DCPEDLYLIEGDVDAFDDSSFNAEELEGAVcVQLNQRQMRYSRFPAIPLFGRAAREQR 787
Cdd:TIGR02169 625 VVEDIEaarrlMGKYRMVTLEgELFEKSGAMTGGSRAPRGGILFSRSEPAEL-QRLRERLEGLKRELSSLQSELRRIENR 703
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 788 LELLREERDDVVEQHAKASFDSQKLQRLYASFNQFVAmHLQVAFDAdPEQALATARDKRNQLLRSISEFEAQEQQLRSQL 867
Cdd:TIGR02169 704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE-ELEEDLSS-LEQEIENVKSELKELEARIEELEEDLHKLEEAL 781
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 868 QASKQALA--ALDKLAPQMGLLDEE--TLEARYHELEEKLQQLSEAKAFIAahgrtiSELEKVAAVLDADPEQFDALEQQ 943
Cdd:TIGR02169 782 NDLEARLShsRIPEIQAELSKLEEEvsRIEARLREIEQKLNRLTLEKEYLE------KEIQELQEQRIDLKEQIKSIEKE 855
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 944 YQQADQALQQLKAQI----FALSDLLERRHHFAySDSVDLLNQSSELS---EQLKAKLVQAESERTRSREELKQAQAQLS 1016
Cdd:TIGR02169 856 IENLNGKKEELEEELeeleAALRDLESRLGDLK-KERDELEAQLRELErkiEELEAQIEKKRKRLSELKAKLEALEEELS 934
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1017 QYNQLLASLKS--SHQAKLETVQEFKQELQEfGVHADE----GAI---ERAQRRRDELQERLHTSRSRKSEYERTITSTE 1087
Cdd:TIGR02169 935 EIEDPKGEDEEipEEELSLEDVQAELQRVEE-EIRALEpvnmLAIqeyEEVLKRLDELKEKRAKLEEERKAILERIEEYE 1013
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
350-659 |
2.07e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.30 E-value: 2.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 350 IERYQEdLEELNFRLEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTRALQYQQAVQALDKARRL 429
Cdd:TIGR02168 673 LERRRE-IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 430 LDKselTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFELVKRVLGEvARSEAAKQAQQVIRQAREAQ 509
Cdd:TIGR02168 752 LSK---ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE-LRAELTLLNEEAANLRERLE 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 510 NVVQNEAQWQAQQRDLERQLEQQR-----------SVRELATQYHKQHRVVLDDAATVELERERHSALLEELETEQENCR 578
Cdd:TIGR02168 828 SLERRIAATERRLEDLEEQIEELSedieslaaeieELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELE 907
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 579 EQRGQLRHQEQELQTQIARFESiapAWIKANDALETLREQSGAELADSQsvMAHMQQVLELEKAQSMAKDKLAERRTKLD 658
Cdd:TIGR02168 908 SKRSELRRELEELREKLAQLEL---RLEGLEVRIDNLQERLSEEYSLTL--EEAEALENKIEDDEEEARRRLKRLENKIK 982
|
.
gi 446494934 659 S 659
Cdd:TIGR02168 983 E 983
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
781-1257 |
1.03e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.87 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 781 RAAREQRLELLREERDDVVEQHAKASFDSQKLQRLYASFNQfvAMHLQVAFDADPEQALATARDKRNQLLRSISEFEAQE 860
Cdd:COG1196 248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQA--EEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 861 QQLRSQLQASKQALAALdklapqmglldEETLEARYHELEEKLQQLSEAKAfiaahgrtisELEKVAAVLDADPEQFDAL 940
Cdd:COG1196 326 AELEEELEELEEELEEL-----------EEELEEAEEELEEAEAELAEAEE----------ALLEAEAELAEAEEELEEL 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 941 EQQYQQADQALQQLKAQIFALSDLLERRhhfaysdsVDLLNQSSELSEQLKAKLVQAESERTRSREELKQAQAQLSQYNQ 1020
Cdd:COG1196 385 AEELLEALRAAAELAAQLEELEEAEEAL--------LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1021 LLASLKSSHQAKLETVQEFKQELQEfgvhadegaierAQRRRDELQERLHTSRSRKSEYERTITSTELEMKALVKRMKKV 1100
Cdd:COG1196 457 EEEALLELLAELLEEAALLEAALAE------------LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1101 EKDYQDLRTFVVNAKAGWCSVLRLARQNDVERRLHKRELAYLSADELRSMSDKSLGALRLAVANNEDLRDALRQSEDNSR 1180
Cdd:COG1196 525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446494934 1181 pERKVLFYIAVYQHLRERIRQDIIRTDDPVEAIEEMEVELARLTEELTQREQRLAISSDSVASIIRKTIQREQNRIR 1257
Cdd:COG1196 605 -ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
382-1065 |
2.23e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.69 E-value: 2.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 382 EERAIisEEEVDSLKSQLADYQQAldvqqtralqYQQAVQALDKARRLLDKSELTAESAQALATQLKAEQETRTSELLAL 461
Cdd:COG4913 219 EEPDT--FEAADALVEHFDDLERA----------HEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 462 KHKLDMSSAAAQQFNHAfelVKRVLGEVARSEAA-KQAQQVIRQAREA--QNVVQNEAQWQAQQRDLERQLEQQRSVRE- 537
Cdd:COG4913 287 QRRLELLEAELEELRAE---LARLEAELERLEARlDALREELDELEAQirGNGGDRLEQLEREIERLERELEERERRRAr 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 538 LATQYHKQHRVVLDDAATVELERERHSALLEELETEQENCREQR-------GQLRHQEQELQTQIARFES----IAPAWI 606
Cdd:COG4913 364 LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALaeaeaalRDLRRELRELEAEIASLERrksnIPARLL 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 607 KANDALETLREQSGAELadsqSVMAHMQQVLELEKAQSMAkdklaerrtkldseIERLaspggsndprLKGLADTLggVL 686
Cdd:COG4913 444 ALRDALAEALGLDEAEL----PFVGELIEVRPEEERWRGA--------------IERV----------LGGFALTL--LV 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 687 LSEIYDDIT--IDDAP------YFSAMYGPARHAIVVSDLSGIKEKLvELDDCP-----EDLYLIEGDVDAFDDssfnAE 753
Cdd:COG4913 494 PPEHYAAALrwVNRLHlrgrlvYERVRTGLPDPERPRLDPDSLAGKL-DFKPHPfrawlEAELGRRFDYVCVDS----PE 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 754 ELEG---AVCVQLnQRQMRYSRF--------PAIPLFGRAAREQrLELLREERDDVVEQHAKASFDSQKLQRLYASFNQF 822
Cdd:COG4913 569 ELRRhprAITRAG-QVKGNGTRHekddrrriRSRYVLGFDNRAK-LAALEAELAELEEELAEAEERLEALEAELDALQER 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 823 VAMHLQVAFDADPEQALATARDKRNQLlrsisefeaqEQQLRsQLQASKQALAALDKLApqmglldeETLEARYHELEEK 902
Cdd:COG4913 647 REALQRLAEYSWDEIDVASAEREIAEL----------EAELE-RLDASSDDLAALEEQL--------EELEAELEELEEE 707
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 903 LQQLSEAkafIAAHGRTISELEKVAAVLDADPEQFDALEQQyqqadqalqqlkaqifALSDLLERRHhfaysDSVDLLNQ 982
Cdd:COG4913 708 LDELKGE---IGRLEKELEQAEEELDELQDRLEAAEDLARL----------------ELRALLEERF-----AAALGDAV 763
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 983 SSELSEQLKAKLVQAESERTRSREELKQAQAQ------------------LSQYNQLLASLKSSHQAKLEtvQEFKQELQ 1044
Cdd:COG4913 764 ERELRENLEERIDALRARLNRAEEELERAMRAfnrewpaetadldadlesLPEYLALLDRLEEDGLPEYE--ERFKELLN 841
|
730 740
....*....|....*....|....*...
gi 446494934 1045 EFG-------VHADEGAIERAQRRRDEL 1065
Cdd:COG4913 842 ENSiefvadlLSKLRRAIREIKERIDPL 869
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
8-55 |
4.14e-07 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 48.37 E-value: 4.14e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446494934 8 QSLTMINWNGFFARTFDID-NLVTTLSGGNGAGKSTTMAAFITALIPDQ 55
Cdd:pfam13555 2 TRLQLINWGTFDGHTIPIDpRGNTLLTGPSGSGKSTLLDAIQTLLVPAK 50
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
781-1235 |
7.27e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.17 E-value: 7.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 781 RAAREQRLELLREERDDVVEQHAKASFDSQKLQRLYASFNQfvAMHLQVAFDADPEQALATARDKRNQLLRSISEFEAQE 860
Cdd:COG1196 325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE--ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 861 QQLRSQLQASKQALAALDKLApqmglldEETLEARYHELEEKLQQLSEAKAFIAAHGRTISELEKVAAVLDADPEQFDAL 940
Cdd:COG1196 403 EELEEAEEALLERLERLEEEL-------EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 941 EQQYQQADQALQQLKAQIFALSDLLERRHHFAYSDSVDLLNQSSELSEQLKAKLVQAESERTRSREELKQAQAQLSQYN- 1019
Cdd:COG1196 476 EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEd 555
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1020 -----QLLASLKSSHQAKLETVQEFKQELQEFGVHADE-GAIERAQRRRDELQERLHTSRSRKSEYERTITSTELEMKAL 1093
Cdd:COG1196 556 devaaAAIEYLKAAKAGRATFLPLDKIRARAALAAALArGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1094 VKRMKKVEKDYQDLRTFVVNAKAGWCSVLRLARQNDVERRLHKRELAYLSADELRSMSDKSLGALRLAVANNEDLRDALR 1173
Cdd:COG1196 636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446494934 1174 QSEDNSRPERKVLFYIAVYQHLRERIRQDIIRTDDPVEAIEEMEVELARLTEELTQREQRLA 1235
Cdd:COG1196 716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
861-1242 |
1.14e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.40 E-value: 1.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 861 QQLRSQLQASKQALAALDklapqmglldeetLEARYHELEEKLQQLSEAKAFIAAHGRTISELEKVAAVLDadpEQFDAL 940
Cdd:COG1196 216 RELKEELKELEAELLLLK-------------LRELEAELEELEAELEELEAELEELEAELAELEAELEELR---LELEEL 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 941 EQQYQQADQALQQLKAQIFALSDLLERRHhfaysdsvdllnqssELSEQLKAKLVQAESERTRSREELKQAQAQLSQYNQ 1020
Cdd:COG1196 280 ELELEEAQAEEYELLAELARLEQDIARLE---------------ERRRELEERLEELEEELAELEEELEELEEELEELEE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1021 LLASLKSSHQAKLETVQEFKQELQEfgvhaDEGAIERAQRRRDELQERLHTSRSRKSEYERTITSTELEMKALVKRMKKV 1100
Cdd:COG1196 345 ELEEAEEELEEAEAELAEAEEALLE-----AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1101 EKDYQDLRTFVVNAkagwcsvlrLARQNDVERRLHKRELAYLSADELRSMSDKSLGALRLAVANNEDLRDALRQSEDNSR 1180
Cdd:COG1196 420 EEELEELEEALAEL---------EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1181 PERKVL--------FYIAVYQHLRERIRQDIIRTDDPVEAIEEMEVELArLTEELTQREQRLAISSDSVA 1242
Cdd:COG1196 491 ARLLLLleaeadyeGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAA-LEAALAAALQNIVVEDDEVA 559
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
786-1144 |
2.82e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 2.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 786 QRLELLREERDDVVEQhakasfdsQKLQRLYASFNQFVamhlqvafdadpeqalatardkrnqLLRSISEFEAQEQQLRS 865
Cdd:TIGR02169 198 QQLERLRREREKAERY--------QALLKEKREYEGYE-------------------------LLKEKEALERQKEAIER 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 866 QLQASKQALAALDKLAPQmglldeetLEARYHELEEKLQQLS---------EAKAFIAAHGRTISELEKVAAVLDADPEQ 936
Cdd:TIGR02169 245 QLASLEEELEKLTEEISE--------LEKRLEEIEQLLEELNkkikdlgeeEQLRVKEKIGELEAEIASLERSIAEKERE 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 937 FDALEQQYQQADQALQQLKAQIFALSDLLERRHhfaySDSVDLLNQSSELSEQLKAKLVQAESERTR---SREELKQAQA 1013
Cdd:TIGR02169 317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEfaeTRDELKDYRE 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1014 QLSQYNQLLASLKSSHQAKLETVQEFKQELQEFgvhadEGAIERAQRRRDELQERLHTSRSRKSEYERtitstelEMKAL 1093
Cdd:TIGR02169 393 KLEKLKREINELKRELDRLQEELQRLSEELADL-----NAAIAGIEAKINELEEEKEDKALEIKKQEW-------KLEQL 460
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 446494934 1094 VKRMKKVEKDYQDLRtfvvnakagwcsvlrlARQNDVERRLHK--RELAYLSA 1144
Cdd:TIGR02169 461 AADLSKYEQELYDLK----------------EEYDRVEKELSKlqRELAEAEA 497
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
299-561 |
7.16e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 7.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 299 RETLIEQNSLLNRVHEELELLVEQESALEQDYQGASDHLQLVQNALRQQEKIERYQEDLEELNFRLEEQMmvvEEANERV 378
Cdd:TIGR02168 694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI---EELEERL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 379 MQAEERAIISEEEVDSLKSQLADYQQALDVQQTRALQYQQAVQALD--------KARRLLDKSELTAESAQALATQLKAE 450
Cdd:TIGR02168 771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNeeaanlreRLESLERRIAATERRLEDLEEQIEEL 850
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 451 QETRTSELLALKHKLDMSSAAAQQFNHAFELVKRVlgEVARSEAAKQAQQVIRQAREA-QNVVQNEAQWQAQQRDLER-Q 528
Cdd:TIGR02168 851 SEDIESLAAEIEELEELIEELESELEALLNERASL--EEALALLRSELEELSEELRELeSKRSELRRELEELREKLAQlE 928
|
250 260 270
....*....|....*....|....*....|....*.
gi 446494934 529 LEQQR---SVRELATQYHKQHRVVLDDAATVELERE 561
Cdd:TIGR02168 929 LRLEGlevRIDNLQERLSEEYSLTLEEAEALENKIE 964
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
781-1265 |
2.38e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 49.35 E-value: 2.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 781 RAAREQRLELLREERDDVVEQHAKASFDSQKLQRLYASFNQFVAMHLQVAFDADPEQAlataRDKRNQLLRSISEFEAQE 860
Cdd:pfam15921 251 KSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA----RNQNSMYMRQLSDLESTV 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 861 QQLRSQLQASKQALA-ALDKLAPQMGLLDEETLEARyheleeklqqlSEAKAFIAAHGRTISELEKVAAVLDADPEQFDA 939
Cdd:pfam15921 327 SQLRSELREAKRMYEdKIEELEKQLVLANSELTEAR-----------TERDQFSQESGNLDDQLQKLLADLHKREKELSL 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 940 LEQQYQQADQALQQLKAQIFALSDLLERRHHFAYSDSVDLLNQSSELSEQLKAKLVQAESeRTRSREELKQAQAQLSQYN 1019
Cdd:pfam15921 396 EKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQG-KNESLEKVSSLTAQLESTK 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1020 QLLASLKSSHQAK---LE----TVQEFKQELQ--EFGVHADEGAIERAQRRRD-ELQERLHTsrsrKSEYERtITSTELE 1089
Cdd:pfam15921 475 EMLRKVVEELTAKkmtLEsserTVSDLTASLQekERAIEATNAEITKLRSRVDlKLQELQHL----KNEGDH-LRNVQTE 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1090 MKALVKRMKKVEKDYQDLRTFVVNA---------KAGWCSVLRLARQNDV-ERRLHKRELAYLSAD------ELRS-MSD 1152
Cdd:pfam15921 550 CEALKLQMAEKDKVIEILRQQIENMtqlvgqhgrTAGAMQVEKAQLEKEInDRRLELQEFKILKDKkdakirELEArVSD 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1153 KSLGALRLAVANNEDL---------RDALRQSEDNSRPERKVLF--YIAVYQHLRERIRQDIIRTDDPVEAIEEMEVELA 1221
Cdd:pfam15921 630 LELEKVKLVNAGSERLravkdikqeRDQLLNEVKTSRNELNSLSedYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELE 709
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 446494934 1222 RLTEELTQRE------QRLAISSDSVASIIRKTIQREQNRIRMLNQGLSN 1265
Cdd:pfam15921 710 QTRNTLKSMEgsdghaMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTN 759
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
333-664 |
5.42e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.91 E-value: 5.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 333 ASDHLQLVQNALRQQEKIERYQEDLEELNFRLEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTR 412
Cdd:pfam12128 592 VPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNK 671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 413 AL-----QYQQAVQALDKARRLLDKseltaESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFELVkrvlg 487
Cdd:pfam12128 672 ALaerkdSANERLNSLEAQLKQLDK-----KHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAAR----- 741
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 488 EVARSEAAKQAQQVIRQAREAQNV-VQNEAQWQAQQRDLERQLEQQRSVRELATQYHK--QHRVVLDDAATVELERERHS 564
Cdd:pfam12128 742 RSGAKAELKALETWYKRDLASLGVdPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDwyQETWLQRRPRLATQLSNIER 821
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 565 ALleeleteqencREQRGQLRHQEQELQTQIARFESIApawiKANDALETLREQSGAELADSQSVMAHM---QQVLELEK 641
Cdd:pfam12128 822 AI-----------SELQQQLARLIADTKLRRAKLEMER----KASEKQQVRLSENLRGLRCEMSKLATLkedANSEQAQG 886
|
330 340
....*....|....*....|...
gi 446494934 642 AQSMAKDKLAERRTKLDSEIERL 664
Cdd:pfam12128 887 SIGERLAQLEDLKLKRDYLSESV 909
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
8-438 |
8.28e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 8.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 8 QSLTMINWNGFFAR-TFDIDNLVTTLSGGNGAGKSTTMAAFITALIPDQSLlHFrNTTEAGSSQASRD-----KGLYGK- 80
Cdd:COG4913 4 QRLQLINWGTFDGVhTIDFDGRGTLLTGDNGSGKSTLLDAIQTLLVPAKRP-RF-NKAANDAGKSDRTllsyvRGKYGSe 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 81 ----------LQAGACYAALDVV---NSRNQRL-LFAVKLQQVAGRDKKvDIKPFLIqglpshVKPTDVLVETVSDkHAR 146
Cdd:COG4913 82 rdeagtrpvyLRPGDTWSAIAATfanDGSGQTVtLAQVFWLKGDASSLG-DVKRFFV------IADGPLDLEDFEE-FAH 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 147 VRQINEVKDAVGQIEGAHFKSFPsivDYHAQMFE-FGVipkklrnssDRSKFYRLieasLYGGIS----SAITRSLRDYL 221
Cdd:COG4913 154 GFDIRALKARLKKQGVEFFDSFS---AYLARLRRrLGI---------GSEKALRL----LHKTQSfkpiGDLDDFVREYM 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 222 LPQnggvKKAFQDMEsALRENRMTL----EAIKTTQADRDLFKHLITESTNYVAADymrhandRRNKVGQTLVLRGELFS 297
Cdd:COG4913 218 LEE----PDTFEAAD-ALVEHFDDLerahEALEDAREQIELLEPIRELAERYAAAR-------ERLAELEYLRAALRLWF 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 298 SRETLIEQNSLLNRVHEELELLVEQESALEQDYQGASDHLQLVQNALRQQ--EKIERYQEDLEELNFRLEEQMMVVEEAN 375
Cdd:COG4913 286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNggDRLEQLEREIERLERELEERERRRARLE 365
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446494934 376 ERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTRA-LQYQQAVQALDKARRllDKSELTAE 438
Cdd:COG4913 366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALeEALAEAEAALRDLRR--ELRELEAE 427
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
837-1047 |
9.69e-05 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 46.99 E-value: 9.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 837 QALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAALDKLAPQMGllDEETLEARYHELE--EKLQQ--------L 906
Cdd:COG0497 158 EEYREAYRAWRALKKELEELRADEAERARELDLLRFQLEELEAAALQPG--EEEELEEERRRLSnaEKLREalqealeaL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 907 SEAKAFIAAH-GRTISELEKVAAV-------------------------------LDADPEQFDALEqqyqqadqalqql 954
Cdd:COG0497 236 SGGEGGALDLlGQALRALERLAEYdpslaelaerlesalieleeaaselrryldsLEFDPERLEEVE------------- 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 955 kAQIFALSDLLeRRHH------FAYSDS----VDLLNQSSELSEQLKAKLVQAESERTRSREEL----KQAQAQLSQY-N 1019
Cdd:COG0497 303 -ERLALLRRLA-RKYGvtveelLAYAEElraeLAELENSDERLEELEAELAEAEAELLEAAEKLsaarKKAAKKLEKAvT 380
|
250 260
....*....|....*....|....*...
gi 446494934 1020 QLLASLKSSHqAKLETVQEFKQELQEFG 1047
Cdd:COG0497 381 AELADLGMPN-ARFEVEVTPLEEPGPNG 407
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
347-674 |
1.08e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.83 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 347 QEKIERYQEDLEELNfrleeqmmvveeanERVMQAEERAIISEEEVDSLKSQLADYQQALDVQ--QTRALQYQQAVQALD 424
Cdd:COG4913 609 RAKLAALEAELAELE--------------EELAEAEERLEALEAELDALQERREALQRLAEYSwdEIDVASAEREIAELE 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 425 KARRLLDKSELTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFELVKRVL---GEVARSEAAKQAQQV 501
Cdd:COG4913 675 AELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLeaaEDLARLELRALLEER 754
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 502 IRQAREAQNVVQNEAQWQAQQRDLERQLEQQRS-VRELATQYHKQHRVVLDDAAT------------VELERER-HSALL 567
Cdd:COG4913 755 FAAALGDAVERELRENLEERIDALRARLNRAEEeLERAMRAFNREWPAETADLDAdleslpeylallDRLEEDGlPEYEE 834
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 568 EELETEQENCREQRGQLRHQ-EQELQTQIARFESIapawikaNDALETLREQSG------AELADSQSVMAHMQQVLELE 640
Cdd:COG4913 835 RFKELLNENSIEFVADLLSKlRRAIREIKERIDPL-------NDSLKRIPFGPGrylrleARPRPDPEVREFRQELRAVT 907
|
330 340 350
....*....|....*....|....*....|....*
gi 446494934 641 KAQSMAKDKLAERR-TKLDSEIERLASPGGSNDPR 674
Cdd:COG4913 908 SGASLFDEELSEARfAALKRLIERLRSEEEESDRR 942
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
346-604 |
1.18e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 346 QQEKIERYQEDLEELNFRLEEQmmvveeaNERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTRALQYQQAVQALDK 425
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAEL-------EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 426 ARRLLDKSEltAESAQALATQLKAEQETRTSELLALKhkldMSSAAAQQFNHAFELVKRVlgevarseAAKQAQQVIRQA 505
Cdd:COG4942 91 EIAELRAEL--EAQKEELAELLRALYRLGRQPPLALL----LSPEDFLDAVRRLQYLKYL--------APARREQAEELR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 506 REAQNVVQNEAQWQAQQRDLERQLEQQRSVRELATQYHKQHRVVLDDAATVELERerhsalleeleteqencREQRGQLR 585
Cdd:COG4942 157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAEL-----------------AAELAELQ 219
|
250
....*....|....*....
gi 446494934 586 HQEQELQTQIARFESIAPA 604
Cdd:COG4942 220 QEAEELEALIARLEAEAAA 238
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
338-1144 |
1.27e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.89 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 338 QLVQNALRQQEKIERYQEDLEELNFRLEeqmMVVEEANERVMQAEERAIISEEEVDSLKSQLADYQQA---LDVQQTRAL 414
Cdd:TIGR00618 177 QYTQLALMEFAKKKSLHGKAELLTLRSQ---LLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQShayLTQKREAQE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 415 QYQQAVQALDKARRLLDksELTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAQQFNHAFELVKRvlgevARSEA 494
Cdd:TIGR00618 254 EQLKKQQLLKQLRARIE--ELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMR-----SRAKL 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 495 AKQAQQVIRQAREAQNVVQNEAQWQAQQRDLERQLEQQRSVRE------------LATQYHKQHRVVLDDAATVELERER 562
Cdd:TIGR00618 327 LMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREiscqqhtltqhiHTLQQQKTTLTQKLQSLCKELDILQ 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 563 HSALLEELETEQEncREQRGQLRHQEQELQTQIARFESIAPAwIKANDALETLREQSGAELADSQSVMAHMQQVLELEKA 642
Cdd:TIGR00618 407 REQATIDTRTSAF--RDLQGQLAHAKKQQELQQRYAELCAAA-ITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHL 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 643 QSMAKDKLAERRTKLDSEIERLASPGGSNDPRLKGLADTLGGvllseiydditiDDAPYFSAMYGPARHAIVVSDLSGik 722
Cdd:TIGR00618 484 QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGP------------LTRRMQRGEQTYAQLETSEEDVYH-- 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 723 eklvELDDCPEDLYLIEGDVDAFDDSSFNAEELEGAVCVQLNQRQMRYSRF-PAIPLFGRAAREQRLELLREERDDVVEQ 801
Cdd:TIGR00618 550 ----QLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLqDLTEKLSEAEDMLACEQHALLRKLQPEQ 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 802 H--AKASFDSQKLQRLYASFNQFVAMHLQVAFDADPEQALATARDKRnQLLRSISEFEAQEQQLRSQLQASKQALAALDk 879
Cdd:TIGR00618 626 DlqDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPK-ELLASRQLALQKMQSEKEQLTYWKEMLAQCQ- 703
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 880 LAPQMGLLDEETLEARYHELEEKLQ-QLSEAKAFIAAHGRTISELEkvaavldadpEQFDaleqqyqqadqalQQLKAQI 958
Cdd:TIGR00618 704 TLLRELETHIEEYDREFNEIENASSsLGSDLAAREDALNQSLKELM----------HQAR-------------TVLKART 760
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 959 FAlsdllerrhHFAYSDSVDLLNQSSELSEQLKAKLVQAESERTRSREELKQAQAQLSQYnqllasLKSSHQAKLETVQE 1038
Cdd:TIGR00618 761 EA---------HFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE------IPSDEDILNLQCET 825
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1039 FKQELQEFG-----VHADEGAIERAQRRRDELQERLHTSRSRKSEYertitsTELEMKALVKRMKKVEKDYQDLRTFVvn 1113
Cdd:TIGR00618 826 LVQEEEQFLsrleeKSATLGEITHQLLKYEECSKQLAQLTQEQAKI------IQLSDKLNGINQIKIQFDGDALIKFL-- 897
|
810 820 830
....*....|....*....|....*....|.
gi 446494934 1114 akAGWCSVLRLARQNDVERRLHKRELAYLSA 1144
Cdd:TIGR00618 898 --HEITLYANVRLANQSEGRFHGRYADSHVN 926
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
841-1297 |
2.47e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.88 E-value: 2.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 841 TARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAALDKLA-PQMGLLDE-ETLEARYHELEEKlqQLSEAKAFIAAHGR 918
Cdd:pfam15921 139 SQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMlSHEGVLQEiRSILVDFEEASGK--KIYEHDSMSTMHFR 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 919 TI-SELEKVAAVLDADpeqfdaleqqyqqadqaLQQLKAQIFALSDLLERRHHFAYSDSVDLLNQSSELSEQL------- 990
Cdd:pfam15921 217 SLgSAISKILRELDTE-----------------ISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLiseheve 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 991 ------KAKLVQAESERTRSREELKQAQA--QLSQYNQLLASLKSshqakleTVQEFKQELQEfGVHADEGAIERAQRRR 1062
Cdd:pfam15921 280 itglteKASSARSQANSIQSQLEIIQEQArnQNSMYMRQLSDLES-------TVSQLRSELRE-AKRMYEDKIEELEKQL 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1063 DELQERLHTSRSRKSEYERTITSTELEMKALVKRMKKVEKDyqdlrtfvvnakagwcsvlrLARQNDVERRLHKRELA-Y 1141
Cdd:pfam15921 352 VLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKE--------------------LSLEKEQNKRLWDRDTGnS 411
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1142 LSADEL-RSMSDKSLGALRLavannEDLRDALRqSEDNSRPERKvlfyIAVYQHLRERIrQDIIRTDDPVEAIEEMeveL 1220
Cdd:pfam15921 412 ITIDHLrRELDDRNMEVQRL-----EALLKAMK-SECQGQMERQ----MAAIQGKNESL-EKVSSLTAQLESTKEM---L 477
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446494934 1221 ARLTEELTQREQRLAiSSDSVASIIRKTIQREQNRIRMLNQGLSNISfgqvngVRLNVKVRESHEILLAGLSEQQAQ 1297
Cdd:pfam15921 478 RKVVEELTAKKMTLE-SSERTVSDLTASLQEKERAIEATNAEITKLR------SRVDLKLQELQHLKNEGDHLRNVQ 547
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
836-1347 |
2.59e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.68 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 836 EQALATARDKRNQLLRsISEFEAQEQQLRSQLQASKQALAALDKLAPQ--MGLLDEETLEARyHELEEKLQQLSEAKAFI 913
Cdd:COG4913 241 HEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALRLWFAQrrLELLEAELEELR-AELARLEAELERLEARL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 914 AAHGRTISELEkvAAVLDADPEQFDALEQQYQQADQALQQLKAQIFALSDLLERRHHFAYSDS---VDLLNQSSELSEQL 990
Cdd:COG4913 319 DALREELDELE--AQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAeefAALRAEAAALLEAL 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 991 KAKLVQAESERTRSREELKQAQAQLSQYNQLLASLKSSHQAKLETVQEFKQEL-QEFGVHADE----------------- 1052
Cdd:COG4913 397 EEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALaEALGLDEAElpfvgelievrpeeerw 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1053 -GAIERA---QRRR----DE-------------LQERLHTSRSRKSEYERTITSteLEMKALVKRMKKVEKDYQD-LRTF 1110
Cdd:COG4913 477 rGAIERVlggFALTllvpPEhyaaalrwvnrlhLRGRLVYERVRTGLPDPERPR--LDPDSLAGKLDFKPHPFRAwLEAE 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1111 VVNAKAGWC------------SVLR--LARQN--------------------DVERRLHKRELAYLSADELRSMSDKSLG 1156
Cdd:COG4913 555 LGRRFDYVCvdspeelrrhprAITRagQVKGNgtrhekddrrrirsryvlgfDNRAKLAALEAELAELEEELAEAEERLE 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1157 ALRLAVANNEDLRDALRQSEDNSRPERKVLFYIAVYQHLRERIRQdiIRTDDPV-----EAIEEMEVELARLTEELTQRE 1231
Cdd:COG4913 635 ALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELER--LDASSDDlaaleEQLEELEAELEELEEELDELK 712
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1232 QRLAISSDSVASiIRKTIQREQNRIRMLNQGLSNISFGQVNGVRLNVKVRESHEILLAGLSEQQAQHKDLFESARytfsE 1311
Cdd:COG4913 713 GEIGRLEKELEQ-AEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAE----E 787
|
570 580 590
....*....|....*....|....*....|....*.
gi 446494934 1312 AMAKLFQRVNPHIDMGQRSpqvLGEELLDYRNYLEL 1347
Cdd:COG4913 788 ELERAMRAFNREWPAETAD---LDADLESLPEYLAL 820
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
833-1072 |
2.64e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.14 E-value: 2.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 833 ADPEQALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAA----LDKLAPQMGLLDEE--TLEARYHELEEKLQQL 906
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlarrIRALEQELAALEAElaELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 907 SEAKAFIAAHGRTISELEKVAAVLDadPEQFDALEQQYQQADQALQQLKAQIFALSDLLERrhhfaysdsvdllnqssel 986
Cdd:COG4942 103 KEELAELLRALYRLGRQPPLALLLS--PEDFLDAVRRLQYLKYLAPARREQAEELRADLAE------------------- 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 987 SEQLKAKLVQAESERTRSREELKQAQAQL----SQYNQLLASLKSSHQAKLETVQEFKQELQEFgvhadEGAIERAQRRR 1062
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALealkAERQKLLARLEKELAELAAELAELQQEAEEL-----EALIARLEAEA 236
|
250
....*....|
gi 446494934 1063 DELQERLHTS 1072
Cdd:COG4942 237 AAAAERTPAA 246
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
325-664 |
2.77e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.73 E-value: 2.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 325 ALEQDYQGASDHLQLVQNALRQ----QEKIERYQEDLEELNFRLEE---QMMVVEEANERVMQAEERAIISEEE--VDSL 395
Cdd:TIGR00618 226 KELKHLREALQQTQQSHAYLTQkreaQEEQLKKQQLLKQLRARIEElraQEAVLEETQERINRARKAAPLAAHIkaVTQI 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 396 KSQLADYQQALDVQQT---RALQYQQAVQALDKARRLLDKSELTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAA 472
Cdd:TIGR00618 306 EQQAQRIHTELQSKMRsraKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQ 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 473 QQFNHAFELVK--RVLGEVARSEAAKQAQQVIRQAREAQNVVQNEAQWQAQQRDLER-----------QLEQQRSVRELA 539
Cdd:TIGR00618 386 QQKTTLTQKLQslCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELcaaaitctaqcEKLEKIHLQESA 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 540 TQYHKQHRVVLDDAATVELERERHSALLEELETEQENCREQRGQLRHQEQELQ------TQIARFESIAPAWIKANDALE 613
Cdd:TIGR00618 466 QSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQdidnpgPLTRRMQRGEQTYAQLETSEE 545
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 446494934 614 TLREQSGAELADSQSVMAHMQQVLELEKAQSMAKDKLAERRTKLDSEIERL 664
Cdd:TIGR00618 546 DVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRL 596
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
833-1235 |
4.90e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 44.65 E-value: 4.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 833 ADPEQALATARDKRNQLLRSISEFEAQEQQLRSQLqASKQALAALDKLAPQMGLLDEETLEARYHELEEKLQqlsEAKAF 912
Cdd:PRK02224 261 EDLRETIAETEREREELAEEVRDLRERLEELEEER-DDLLAEAGLDDADAEAVEARREELEDRDEELRDRLE---ECRVA 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 913 IAAHGRTISELEKVAAVLDADP----EQFDALEQQYQQADQALQQLKAQIFAL-SDLLERRHHFAysDSVDLLNQSSELS 987
Cdd:PRK02224 337 AQAHNEEAESLREDADDLEERAeelrEEAAELESELEEAREAVEDRREEIEELeEEIEELRERFG--DAPVDLGNAEDFL 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 988 EQLKAKLVQAESERTRSREELKQAQAQLSQYNQLLASLKSShqakletvqEFKQELQEFGvHADegAIERAQRRRDELQE 1067
Cdd:PRK02224 415 EELREERDELREREAELEATLRTARERVEEAEALLEAGKCP---------ECGQPVEGSP-HVE--TIEEDRERVEELEA 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1068 RLHTSRSRKSEYERTITSTElEMKALVKRMKKVEKDYQDLRTFVVNAKAgwcsvlRLARQNDVERRLHKRelaylsADEL 1147
Cdd:PRK02224 483 ELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRE------TIEEKRERAEELRER------AAEL 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1148 RSMSDKSLGALRLAVANNEDLRDAL-----RQSEDNSRPERkvlfyiavyqhlRERIRQDIIRTDDPVEAIEEMEVELAR 1222
Cdd:PRK02224 550 EAEAEEKREAAAEAEEEAEEAREEVaelnsKLAELKERIES------------LERIRTLLAAIADAEDEIERLREKREA 617
|
410
....*....|...
gi 446494934 1223 LTEELTQREQRLA 1235
Cdd:PRK02224 618 LAELNDERRERLA 630
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
861-1108 |
7.84e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.14 E-value: 7.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 861 QQLRSQLQASKQALAALDKLAPQMGLLDEetLEARYHELEEKLQQLSEAKAFIAAhgRTISELEKVAAVLDadpEQFDAL 940
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLEP--IRELAERYAAARERLAELEYLRAA--LRLWFAQRRLELLE---AELEEL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 941 EQQYQQADQALQQLKAQIFALSDLLERRHHfaysdsvDLLNQSSELSEQLKAKLVQAEsertrsrEELKQAQAQLSQYNQ 1020
Cdd:COG4913 301 RAELARLEAELERLEARLDALREELDELEA-------QIRGNGGDRLEQLEREIERLE-------RELEERERRRARLEA 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1021 LLASLKSSHQAKLETVQEFKQELQEFgvhadegaIERAQRRRDELQERLHTSRSRKSEYERTITSTELEMKALVKRMKKV 1100
Cdd:COG4913 367 LLAALGLPLPASAEEFAALRAEAAAL--------LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNI 438
|
....*...
gi 446494934 1101 EKDYQDLR 1108
Cdd:COG4913 439 PARLLALR 446
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
981-1240 |
7.88e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.06 E-value: 7.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 981 NQSSELSEQLKAKLVQAESERTRSREELKQAQAQLSQYNQLLASLKSShqakletvqefkqelQEFGVHADEGAIERAQR 1060
Cdd:pfam12128 593 PEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASRE---------------ETFARTALKNARLDLRR 657
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1061 RRDELQ-ERLHTSRSRKSEY---ERTITSTELEMKALVKRMKKVEKDYQ-DLRTFVVNAKAGWCSVL--------RLARQ 1127
Cdd:pfam12128 658 LFDEKQsEKDKKNKALAERKdsaNERLNSLEAQLKQLDKKHQAWLEEQKeQKREARTEKQAYWQVVEgaldaqlaLLKAA 737
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1128 NDVERRLHKRELAYLSADELRSMSDKSLGALRLAVANNEdLRDALRQSEDNSRPERKVLFYIAVYQHLRERIRQDIIRTD 1207
Cdd:pfam12128 738 IAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKRE-IRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQL 816
|
250 260 270
....*....|....*....|....*....|....
gi 446494934 1208 DPVE-AIEEMEVELARLTEELTQREQRLAISSDS 1240
Cdd:pfam12128 817 SNIErAISELQQQLARLIADTKLRRAKLEMERKA 850
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
833-1318 |
8.26e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.28 E-value: 8.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 833 ADPEQALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAAL-DKLAPQMGLLDEetLEARYHELEEKLQQLSEAKA 911
Cdd:TIGR02168 298 SRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELeEKLEELKEELES--LEAELEELEAELEELESRLE 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 912 FIAAhgrtisELEKVAAVLDADPEQFDALEQQYQQADQALQQLKAQIFALSDllERRHHFAYSDSVDLLNQSSELSEqLK 991
Cdd:TIGR02168 376 ELEE------QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ--EIEELLKKLEEAELKELQAELEE-LE 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 992 AKLVQAESERTRSREELKQAQAQLSQYNQLLASLKS---SHQAKLETVQEFKQELQEFgvHADEGAIERAQRRRDELQER 1068
Cdd:TIGR02168 447 EELEELQEELERLEEALEELREELEEAEQALDAAERelaQLQARLDSLERLQENLEGF--SEGVKALLKNQSGLSGILGV 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1069 LHTSRSRKSEYERTITstelemKALVKRMKKV----EKDYQDLRTFVVNAKAGWCSVLRLAR------QNDVERRLHKRE 1138
Cdd:TIGR02168 525 LSELISVDEGYEAAIE------AALGGRLQAVvvenLNAAKKAIAFLKQNELGRVTFLPLDSikgteiQGNDREILKNIE 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1139 LAYLSADELRSMSDKSLGAL-----RLAVAnnEDLRDALRQSEDNSRPERKV------------------------LFYI 1189
Cdd:TIGR02168 599 GFLGVAKDLVKFDPKLRKALsyllgGVLVV--DDLDNALELAKKLRPGYRIVtldgdlvrpggvitggsaktnssiLERR 676
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1190 AVYQHLRERIRQDIIRTDDPVEAIEEMEVELARLTEELTQREQRLAISSDSVA------SIIRKTIQREQNRIRMLNQGL 1263
Cdd:TIGR02168 677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISalrkdlARLEAEVEQLEERIAQLSKEL 756
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446494934 1264 SNIS------FGQVNGVRLNVKVRESHeilLAGLSEQQAQHKDLFESARYTFSEAMAKLFQ 1318
Cdd:TIGR02168 757 TELEaeieelEERLEEAEEELAEAEAE---IEELEAQIEQLKEELKALREALDELRAELTL 814
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
338-531 |
1.03e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 43.75 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 338 QLVQNALRQQEKIERYQEDLEELNFRLEEQMMVVEEANERV------MQAEERAIIS-------EEEVDSLKSQLADYQQ 404
Cdd:PRK11281 63 QDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELealkddNDEETRETLStlslrqlESRLAQTLDQLQNAQN 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 405 ALDV-------QQTRALQYQ----QAVQALDKARRLL-----DKSELTAESAQALATQLKA--------EQETRTSELL- 459
Cdd:PRK11281 143 DLAEynsqlvsLQTQPERAQaalyANSQRLQQIRNLLkggkvGGKALRPSQRVLLQAEQALlnaqndlqRKSLEGNTQLq 222
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446494934 460 -ALKHKLDMSSAAAQQFNHAFELVKRVLGEVARSEAAKQAQQVIRQaREAQNVVQNeaQWQAQQRDLERQLEQ 531
Cdd:PRK11281 223 dLLQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEKTVQEAQSQ-DEAARIQAN--PLVAQELEINLQLSQ 292
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
346-541 |
1.06e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.28 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 346 QQEKIERYQEDLEELNFRLEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTralQYQQAVQALDK 425
Cdd:COG3883 21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE---ELGERARALYR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 426 ARRLLDKSE--LTAESAQALATQ---LKAEQETRTSELLALKHKLDMSSAAAQQFNHAFELVKRVLGEVARSEAAKQAQQ 500
Cdd:COG3883 98 SGGSVSYLDvlLGSESFSDFLDRlsaLSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446494934 501 VIRQAREAQnVVQNEAQWQAQQRDLERQLEQQRSVRELATQ 541
Cdd:COG3883 178 AEQEALLAQ-LSAEEAAAEAQLAELEAELAAAEAAAAAAAA 217
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
388-531 |
1.06e-03 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 42.80 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 388 SEEEVDSLKSQLADYQQALDVQQTRALQYQQAVQALDKARRLLDKSELTAESAQALATQLKAEQETRTSELLALKHKLDM 467
Cdd:pfam00529 56 YQAALDSAEAQLAKAQAQVARLQAELDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPI 135
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446494934 468 SSAAAQQFNHAFELVKRVLGEVARSEA--AKQAQQVIRQAREAQNVVQNE-AQWQAQQRDLERQLEQ 531
Cdd:pfam00529 136 GGISRESLVTAGALVAQAQANLLATVAqlDQIYVQITQSAAENQAEVRSElSGAQLQIAEAEAELKL 202
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
772-1175 |
1.13e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 772 RFPAIPLFGRAAREQRLELLREERDD---VVEQHAKASFDSQKLQRLYASFNQFVAMHLQVAFDADPEQALATARDKRNQ 848
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEyaeLQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 849 LLRSISEFEAQEQQLRSQLQASKQALAALDKLAPQMGLLDEETLEARYHELEEKLQQLSEAKAFIAAHGRTISELEKVAA 928
Cdd:COG4717 144 LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELE 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 929 VLDadpEQFDALEQQYQQADQALQQLKAQIFALS--------------------------------------DLLERRHH 970
Cdd:COG4717 224 ELE---EELEQLENELEAAALEERLKEARLLLLIaaallallglggsllsliltiagvlflvlgllallfllLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 971 FAYSDSVDLLNQSSELSEQLKAKLVQAES-ERTRSREELKQAQAQLSQYNQLLASLKS-SHQAKLETV-QEFKQELQEFG 1047
Cdd:COG4717 301 GKEAEELQALPALEELEEEELEELLAALGlPPDLSPEELLELLDRIEELQELLREAEElEEELQLEELeQEIAALLAEAG 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1048 VHADEGAIERAQR---------RRDELQERLHTSRSRKSEYERTITSTELEMKA--LVKRMKKVEKDYQDLRTFVVNAKA 1116
Cdd:COG4717 381 VEDEEELRAALEQaeeyqelkeELEELEEQLEELLGELEELLEALDEEELEEELeeLEEELEELEEELEELREELAELEA 460
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 446494934 1117 GwcsVLRLARQNDVERRLHKRELAylsADELRSMSDKSLgALRLAVANNEDLRDALRQS 1175
Cdd:COG4717 461 E---LEQLEEDGELAELLQELEEL---KAELRELAEEWA-ALKLALELLEEAREEYREE 512
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
832-1101 |
1.88e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 42.72 E-value: 1.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 832 DADPEQALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAAldklapqmgllDEETLEaryhELEEKLQQLSEAKA 911
Cdd:PRK02224 201 EKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEE-----------HEERRE----ELETLEAEIEDLRE 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 912 FIAAhgrTISELEKVAAVLDADPEQFDALEQQYQQADQALQQLKAQIFALSDLLErrhhfaysdsvDLLNQSSELSEQLK 991
Cdd:PRK02224 266 TIAE---TEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARRE-----------ELEDRDEELRDRLE 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 992 AKLVQA---ESERTRSREELKQAQAQLSQYNQLLASLKSSHQAKLETVQEFKQELQEF--GVHADEGAIERAQRRRDELQ 1066
Cdd:PRK02224 332 ECRVAAqahNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELeeEIEELRERFGDAPVDLGNAE 411
|
250 260 270
....*....|....*....|....*....|....*
gi 446494934 1067 ERLHTSRSRKSEYERTITSTELEMKALVKRMKKVE 1101
Cdd:PRK02224 412 DFLEELREERDELREREAELEATLRTARERVEEAE 446
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
347-656 |
2.10e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.82 E-value: 2.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 347 QEKIERYQEDLEELNFRLEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTRALQYQQAVQALDKA 426
Cdd:PTZ00121 1321 KKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA 1400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 427 RRLLDKSE----LTAESAQALATQLKAEQETRTSELLA----------LKHKLDMSSAA------AQQFNHAFELVKRVL 486
Cdd:PTZ00121 1401 EEDKKKADelkkAAAAKKKADEAKKKAEEKKKADEAKKkaeeakkadeAKKKAEEAKKAeeakkkAEEAKKADEAKKKAE 1480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 487 GEVARSEAAKQAQQVIRQAREAQNVVQ-----NEAQWQAQQRDLE--RQLEQQRSVRELATQYHKQHRVVLDDAATVELE 559
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKADEAKKAAEakkkaDEAKKAEEAKKADeaKKAEEAKKADEAKKAEEKKKADELKKAEELKKA 1560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 560 RERHSALLEELETEQENCREQRGQLRHQEQELQTQIARFESIAPAWIKANDALETLREQSGAEladsqsvmaHMQQVLEL 639
Cdd:PTZ00121 1561 EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE---------ELKKAEEE 1631
|
330
....*....|....*..
gi 446494934 640 EKAQSMAKDKLAERRTK 656
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKK 1648
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
781-1003 |
2.91e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 2.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 781 RAAREQRLELLREERDDVVEQHAKASFDSQKLQRLYASFNQFVAmhlqvafdaDPEQALATARDKRNQLLRSISEFEAQE 860
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIA---------ALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 861 QQLRSQLQASKQALAALDKLAPQMGLLDEETLEARYHELEEK------LQQLSEA-KAFIAAHGRTISELEKVAAVLDAD 933
Cdd:COG4942 93 AELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvrrlqyLKYLAPArREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 934 PEQFDALEQQYQQADQALQQLKAQIFALSDLLERRHHfAYSDSVDLLNQSSELSEQLKAKLVQAESERTR 1003
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELA-ELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
336-544 |
4.46e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 4.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 336 HLQLVQNALRQQEKIERYQEDLEELNFR----LEEQMMVVEEANERVMQAEERAIISEEEVDSLKSQLADYQQALDvQQT 411
Cdd:COG4717 44 RAMLLERLEKEADELFKPQGRKPELNLKelkeLEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-KLE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 412 RALQYQQAVQALDKARRLLDKSELTAEsaqalatQLKAEQEtrtsELLALKHKLDMSSAAAQQFNHAFELVKRVLGEVAR 491
Cdd:COG4717 123 KLLQLLPLYQELEALEAELAELPERLE-------ELEERLE----ELRELEEELEELEAELAELQEELEELLEQLSLATE 191
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446494934 492 SEAAKQAQQVIRQAREAQNVVQNEAQWQAQQRDLERQLEQQRSVRELATQYHK 544
Cdd:COG4717 192 EELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEER 244
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
435-674 |
4.69e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 4.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 435 LTAESAQALATQLKAEQETRTSELLALKHKLDMSSAAAqqfnhafelvKRVLGEVARSEAA-KQAQQVIRQAREAQNVVQ 513
Cdd:COG4942 13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEE----------KALLKQLAALERRiAALARRIRALEQELAALE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 514 NE-AQWQAQQRDLERQLEQQRSV--RELATQY--HKQHRVVL----DDAATVELERERHSALLEELETEQENCREQRGQL 584
Cdd:COG4942 83 AElAELEKEIAELRAELEAQKEElaELLRALYrlGRQPPLALllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 585 RHQEQELQTQIARFESIAPAWIKANDALETLREQSGAELADSQSVMAHMQQVLELEKAQSMAKDKLAERRTKLDSEIERL 664
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
250
....*....|
gi 446494934 665 ASPGGSNDPR 674
Cdd:COG4942 243 TPAAGFAALK 252
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
833-1235 |
5.21e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.59 E-value: 5.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 833 ADPEQALATARDKRNQLLRSISEFEAQEQQLRSQLQASKQALAALDKLAPQMGLLDEET--LEARYHELEEKLQQLSEAk 910
Cdd:PRK03918 189 ENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELesLEGSKRKLEEKIRELEER- 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 911 afIAAHGRTISELEKVAAVLdadpEQFDALEQQYQQADQALQQLKAQIFALSDLLERrhhfaysdsvdLLNQSSELSEQL 990
Cdd:PRK03918 268 --IEELKKEIEELEEKVKEL----KELKEKAEEYIKLSEFYEEYLDELREIEKRLSR-----------LEEEINGIEERI 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 991 K--AKLVQAESERTRSREELKQAQAQLSQYNQLLASLKsshqAKLETVQEFKQELQEFGVHADEGAIERAQRRRDELQER 1068
Cdd:PRK03918 331 KelEEKEERLEELKKKLKELEKRLEELEERHELYEEAK----AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEE 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1069 LHTSRSRKSEYERTITSTELEMKALVKR-------------------MKKVEKDYQDLRTFVVNAKAGWCSVLRLARQND 1129
Cdd:PRK03918 407 ISKITARIGELKKEIKELKKAIEELKKAkgkcpvcgrelteehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELE 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1130 VERRLHKRELAYLS-ADELRSMSDKslgalrLAVANNEDLRDALRQsednsrperkvlfyiavYQHLRER---IRQDIIR 1205
Cdd:PRK03918 487 KVLKKESELIKLKElAEQLKELEEK------LKKYNLEELEKKAEE-----------------YEKLKEKlikLKGEIKS 543
|
410 420 430
....*....|....*....|....*....|
gi 446494934 1206 TDDPVEAIEEMEVELARLTEELTQREQRLA 1235
Cdd:PRK03918 544 LKKELEKLEELKKKLAELEKKLDELEEELA 573
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
347-535 |
5.35e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.16 E-value: 5.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 347 QEKIERYQEDLEELNFRLEEQMmvveeANERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTRALQYQQAVQALDKA 426
Cdd:COG3206 181 EEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 427 RRLLDKSELTAESAQALATQLKAEQETRTS------ELLALKHKLDMSSAAAQQfnhafeLVKRVLG--EVARSEAAKQA 498
Cdd:COG3206 256 LPELLQSPVIQQLRAQLAELEAELAELSARytpnhpDVIALRAQIAALRAQLQQ------EAQRILAslEAELEALQARE 329
|
170 180 190
....*....|....*....|....*....|....*..
gi 446494934 499 QQVIRQAREAQNVVQNEAQWQAQQRDLERQLEQQRSV 535
Cdd:COG3206 330 ASLQAQLAQLEARLAELPELEAELRRLEREVEVAREL 366
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
978-1266 |
5.47e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.16 E-value: 5.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 978 DLLNQ-SSELSEQLKAKLVQAESERTRSREELKQAQAQLSQYNQLLASLKSSHQAKLETVQEFKQELQEfgvhaDEGAIE 1056
Cdd:TIGR04523 299 DLNNQkEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE-----KQNEIE 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1057 RAQRRRDELQERLHTSRSRKSEYERTITSTELEMKALVKRMKKVEKDYQDLrtfvvnakagwcsvlrlarQNDVERRLHK 1136
Cdd:TIGR04523 374 KLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL-------------------EKEIERLKET 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 1137 RElayLSADELRSMSDKsLGALRLAVANNEDLRDALRQsednsrperkvlfYIAVYQHLRERIRQDIirtDDPVEAIEEM 1216
Cdd:TIGR04523 435 II---KNNSEIKDLTNQ-DSVKELIIKNLDNTRESLET-------------QLKVLSRSINKIKQNL---EQKQKELKSK 494
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 446494934 1217 EVELARLTEELTQREQRLAISSDSVASIIRKtIQREQNRIRMLNQGLSNI 1266
Cdd:TIGR04523 495 EKELKKLNEEKKELEEKVKDLTKKISSLKEK-IEKLESEKKEKESKISDL 543
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
827-1043 |
6.44e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.16 E-value: 6.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 827 LQVAF-DADPEQALATA------------RDKRNQLLRSISEFEAQEQQLRSQLQASKQALAALdKLAPQMGLLDEET-- 891
Cdd:COG3206 138 IEISYtSPDPELAAAVAnalaeayleqnlELRREEARKALEFLEEQLPELRKELEEAEAALEEF-RQKNGLVDLSEEAkl 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 892 LEARYHELEEKLQ----QLSEAKAFIAAHGRTISELEKVAAVLDADPEQFDALEQQYQQadqalqqlKAQIFALSDLLER 967
Cdd:COG3206 217 LLQQLSELESQLAearaELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAEL--------EAELAELSARYTP 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 968 RHhfaySDSVDLLNQSSELSEQLKAK----LVQAESERTRSREELKQAQAQLSQYNQLLASL--KSSHQAKLETVQEFKQ 1041
Cdd:COG3206 289 NH----PDVIALRAQIAALRAQLQQEaqriLASLEAELEALQAREASLQAQLAQLEARLAELpeLEAELRRLEREVEVAR 364
|
..
gi 446494934 1042 EL 1043
Cdd:COG3206 365 EL 366
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
338-664 |
6.81e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.21 E-value: 6.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 338 QLVQNALRQQEKIERYQEDLEELNFRLEEQmmvveeaNERVMQAEERAIISEEEVDSLKSQLADYQQALDVQQTRALQYQ 417
Cdd:TIGR02169 706 ELSQELSDASRKIGEIEKEIEQLEQEEEKL-------KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLE 778
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 418 QAVQALdKARRLLDKSELTAESAQALATQLKaEQETRTSELLALKHKLDMSSAAAQQfNHAFELVKRVLGEVARSEAAKQ 497
Cdd:TIGR02169 779 EALNDL-EARLSHSRIPEIQAELSKLEEEVS-RIEARLREIEQKLNRLTLEKEYLEK-EIQELQEQRIDLKEQIKSIEKE 855
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 498 AQQVIRQAREAQnvvQNEAQWQAQQRDLERQLEQ-QRSVRELATQYHKQHRVVLDDAATVELERERHSALLeeleteqen 576
Cdd:TIGR02169 856 IENLNGKKEELE---EELEELEAALRDLESRLGDlKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK--------- 923
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 577 crEQRGQLRHQEQELQTQIARFESIAPAWIKANDaLETLREQSGAELADSQSV-MAHMQQVLELEKAQSMAKDK---LAE 652
Cdd:TIGR02169 924 --AKLEALEEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRALEPVnMLAIQEYEEVLKRLDELKEKrakLEE 1000
|
330
....*....|..
gi 446494934 653 RRTKLDSEIERL 664
Cdd:TIGR02169 1001 ERKAILERIEEY 1012
|
|
| PspA |
COG1842 |
Phage shock protein A [Transcription, Signal transduction mechanisms]; |
496-666 |
7.36e-03 |
|
Phage shock protein A [Transcription, Signal transduction mechanisms];
Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 39.81 E-value: 7.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 496 KQAQQVIRQAREA-QNVVQNEAQWQAQQRDLERQLEQQRsvrELATQYHKQHRVVL----DDAATVELER-ERHSALLEE 569
Cdd:COG1842 26 KMLDQAIRDMEEDlVEARQALAQVIANQKRLERQLEELE---AEAEKWEEKARLALekgrEDLAREALERkAELEAQAEA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494934 570 LETEQENCREQRGQLRHQEQELQTQIARFES---IAPAWIKANDALETLREQ-SGAELADSQSVMAHMQQVLELEKAQSM 645
Cdd:COG1842 103 LEAQLAQLEEQVEKLKEALRQLESKLEELKAkkdTLKARAKAAKAQEKVNEAlSGIDSDDATSALERMEEKIEEMEARAE 182
|
170 180
....*....|....*....|.
gi 446494934 646 AKDKLAERRTkLDSEIERLAS 666
Cdd:COG1842 183 AAAELAAGDS-LDDELAELEA 202
|
|
| |
