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Conserved domains on  [gi|446501024|ref|WP_000578878|]
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MULTISPECIES: helix-turn-helix domain-containing protein [Bacillus]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11443820)

helix-turn-helix domain-containing protein such as an XRE (Xenobiotic Response Element) family transcriptional regulator SinR of Bacillus subtilis, which represses biofilm formation by binding to the respective eps promoter

Gene Ontology:  GO:0003677|GO:0006355

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-71 9.66e-22

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 81.20  E-value: 9.66e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446501024   1 MIGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLLHDETTKEAN 71
Cdd:COG1396    7 ALGERLRELRKARGLTQEELAERLGVSRSTISRIERG-RRNPSLETLLKLAKALGVSLDELLGGADEELPE 76
SinI pfam08671
Anti-repressor SinI; SinR is a pleiotropic regulator of several late growth processes. It is a ...
72-99 5.80e-11

Anti-repressor SinI; SinR is a pleiotropic regulator of several late growth processes. It is a tetrameric DNA binding protein whose activity is down-regulated thorough the formation of a SinI:SinR protein complex. When complexed with SinI, the SinR tetramer is disrupted such that is no longer able to bind DNA.


:

Pssm-ID: 400831  Cd Length: 28  Bit Score: 52.42  E-value: 5.80e-11
                          10        20
                  ....*....|....*....|....*...
gi 446501024   72 LDSEWTQLVKDAMNSGVSKEQFREFLEF 99
Cdd:pfam08671   1 LDEEWVELIKEAMESGLSKEEFREFLEF 28
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-71 9.66e-22

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 81.20  E-value: 9.66e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446501024   1 MIGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLLHDETTKEAN 71
Cdd:COG1396    7 ALGERLRELRKARGLTQEELAERLGVSRSTISRIERG-RRNPSLETLLKLAKALGVSLDELLGGADEELPE 76
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
3-61 2.58e-16

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 66.81  E-value: 2.58e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446501024   3 GERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTL 61
Cdd:cd00093    1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENG-KRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
5-61 4.49e-15

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 63.69  E-value: 4.49e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 446501024     5 RIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTL 61
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENG-KRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
6-61 7.78e-13

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 57.94  E-value: 7.78e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 446501024    6 IKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTL 61
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENG-KREPSLETLKKLAEALGVSLDEL 55
SinI pfam08671
Anti-repressor SinI; SinR is a pleiotropic regulator of several late growth processes. It is a ...
72-99 5.80e-11

Anti-repressor SinI; SinR is a pleiotropic regulator of several late growth processes. It is a tetrameric DNA binding protein whose activity is down-regulated thorough the formation of a SinI:SinR protein complex. When complexed with SinI, the SinR tetramer is disrupted such that is no longer able to bind DNA.


Pssm-ID: 400831  Cd Length: 28  Bit Score: 52.42  E-value: 5.80e-11
                          10        20
                  ....*....|....*....|....*...
gi 446501024   72 LDSEWTQLVKDAMNSGVSKEQFREFLEF 99
Cdd:pfam08671   1 LDEEWVELIKEAMESGLSKEEFREFLEF 28
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
1-79 7.04e-10

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 54.19  E-value: 7.04e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446501024   1 MIGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLLHDETTKEAnldsEWTQL 79
Cdd:PRK08154  28 ALGERVRTLRARRGMSRKVLAQASGVSERYLAQLESG-QGNVSILLLRRVARALGCSLADLLGDVDTSSP----DWLLI 101
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-71 9.66e-22

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 81.20  E-value: 9.66e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446501024   1 MIGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLLHDETTKEAN 71
Cdd:COG1396    7 ALGERLRELRKARGLTQEELAERLGVSRSTISRIERG-RRNPSLETLLKLAKALGVSLDELLGGADEELPE 76
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-65 7.40e-17

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 68.34  E-value: 7.40e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446501024   1 MIGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLLHDE 65
Cdd:COG1476    4 KLGNRLKELRKERGLTQEELAELLGVSRQTISAIENG-KYNPSLELALKIARALGVSLEELFSLE 67
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
3-61 2.58e-16

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 66.81  E-value: 2.58e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446501024   3 GERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTL 61
Cdd:cd00093    1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENG-KRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
5-61 4.49e-15

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 63.69  E-value: 4.49e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 446501024     5 RIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTL 61
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENG-KRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
6-61 7.78e-13

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 57.94  E-value: 7.78e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 446501024    6 IKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTL 61
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENG-KREPSLETLKKLAEALGVSLDEL 55
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
2-59 1.74e-12

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 57.26  E-value: 1.74e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446501024   2 IGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVD 59
Cdd:COG1813   13 YGERIREAREARGLSQEELAEKLGVSESTIRRIERG-EATPSLDTLRKLEKALGISLA 69
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
2-63 1.58e-11

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 54.84  E-value: 1.58e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446501024    2 IGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNLQKNPSIQFLEKIAAVLQIPVDTLLH 63
Cdd:pfam13560   2 LGARLRRLRERAGLSQEALARRLGVSRSTLSRLETGRRGRPSPAVVERLARALGVDGAERAE 63
SinI pfam08671
Anti-repressor SinI; SinR is a pleiotropic regulator of several late growth processes. It is a ...
72-99 5.80e-11

Anti-repressor SinI; SinR is a pleiotropic regulator of several late growth processes. It is a tetrameric DNA binding protein whose activity is down-regulated thorough the formation of a SinI:SinR protein complex. When complexed with SinI, the SinR tetramer is disrupted such that is no longer able to bind DNA.


Pssm-ID: 400831  Cd Length: 28  Bit Score: 52.42  E-value: 5.80e-11
                          10        20
                  ....*....|....*....|....*...
gi 446501024   72 LDSEWTQLVKDAMNSGVSKEQFREFLEF 99
Cdd:pfam08671   1 LDEEWVELIKEAMESGLSKEEFREFLEF 28
RodZ COG1426
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ...
2-62 1.32e-10

Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441035 [Multi-domain]  Cd Length: 71  Bit Score: 52.50  E-value: 1.32e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446501024   2 IGERIKRLRLQKGISLTELAEKAGVAKSYISSIER-NLQKNPS----IQFLEKIAAVLQIPVDTLL 62
Cdd:COG1426    6 IGELLRQAREAKGLSLEDVAERTKISVSYLEAIEEgDFDALPGpvyvRGFLRSYARALGLDPEELL 71
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
2-62 1.62e-10

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 53.10  E-value: 1.62e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446501024   2 IGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLL 62
Cdd:COG3620   18 LGEALRLMRKELGLSQLPVAELVGVSQSDILRIESG-KRDPTVSTLEKIAEALGKELSAVL 77
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
1-79 7.04e-10

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 54.19  E-value: 7.04e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446501024   1 MIGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLLHDETTKEAnldsEWTQL 79
Cdd:PRK08154  28 ALGERVRTLRARRGMSRKVLAQASGVSERYLAQLESG-QGNVSILLLRRVARALGCSLADLLGDVDTSSP----DWLLI 101
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
3-65 1.42e-09

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 49.98  E-value: 1.42e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446501024    3 GERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLLHDE 65
Cdd:pfam12844   1 GERLRKAREERGLTQEELAERLGISRSQLSAIENG-KSVPPAETLYKIAELLGVPANWLLQGE 62
YozG COG3655
DNA-binding transcriptional regulator, XRE family [Transcription];
1-62 2.00e-08

DNA-binding transcriptional regulator, XRE family [Transcription];


Pssm-ID: 442872 [Multi-domain]  Cd Length: 69  Bit Score: 47.06  E-value: 2.00e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446501024   1 MIGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNLQKNPSIQFLEKIAAVLQIPVDTLL 62
Cdd:COG3655    1 MIYVKLDELLAERGMTKKELAEATGISRATLSRLKNGKAKAVRLDTLEKICKALDCQPGDLL 62
PRK13890 PRK13890
conjugal transfer protein TrbA; Provisional
6-73 6.05e-08

conjugal transfer protein TrbA; Provisional


Pssm-ID: 237547 [Multi-domain]  Cd Length: 120  Bit Score: 47.05  E-value: 6.05e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446501024   6 IKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLLHDETTKEANLD 73
Cdd:PRK13890  10 VLRLLDERHMTKKELSERSGVSISFLSDLTTG-KANPSLKVMEAIADALETPLPLLLESTDLDKEALD 76
HTH_26 pfam13443
Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to ...
5-62 6.69e-07

Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433211 [Multi-domain]  Cd Length: 63  Bit Score: 42.91  E-value: 6.69e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446501024    5 RIKRLRLQKGISLTELAEKAGVAKSYISSIERNLQKNPSIQFLEKIAAVLQIPVDTLL 62
Cdd:pfam13443   1 KLRKLMADRGISKSDLARATGISRATLSRLRKGKPKRVSLDTLDKICDALGCQPGDLL 58
PRK09943 PRK09943
HTH-type transcriptional regulator PuuR;
1-58 1.46e-06

HTH-type transcriptional regulator PuuR;


Pssm-ID: 182158 [Multi-domain]  Cd Length: 185  Bit Score: 44.40  E-value: 1.46e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446501024   1 MIGERIKRLRLQKGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPV 58
Cdd:PRK09943   7 APGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQD-KVSPAISTLQKLLKVYGLSL 63
COG1709 COG1709
Predicted transcriptional regulator,contains XRE-type HTH domain [Transcription];
3-65 1.17e-05

Predicted transcriptional regulator,contains XRE-type HTH domain [Transcription];


Pssm-ID: 441315  Cd Length: 234  Bit Score: 42.09  E-value: 1.17e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446501024   3 GERIKRLRLQKGISLTELAEKAGVAKSYISSIERNLQKNPSIQFLEKIaavlqipVDTLL-HDE 65
Cdd:COG1709   24 GETLRKWREDFGISQTELARELGVSPSVISDYESGRRKSPGIAFVKKF-------VEALLeIDE 80
COG1395 COG1395
Predicted transcriptional regulator [Transcription];
3-58 5.65e-05

Predicted transcriptional regulator [Transcription];


Pssm-ID: 441005 [Multi-domain]  Cd Length: 313  Bit Score: 40.21  E-value: 5.65e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446501024   3 GERIKRLRLQKGISLTELAEKAGVAKSYISSIERNLQkNPSIQFLEKIAAVLQIPV 58
Cdd:COG1395  129 GEKLRELREERGLSLGELASELGVSRRTISKYERGEM-DASIEVALKLEEILGEPI 183
PRK04140 PRK04140
transcriptional regulator;
3-44 2.49e-04

transcriptional regulator;


Pssm-ID: 235224 [Multi-domain]  Cd Length: 317  Bit Score: 38.30  E-value: 2.49e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 446501024   3 GERIKRLRLQKGISLTELAEKAGVAKSYISSIERNLQkNPSI 44
Cdd:PRK04140 128 GDVLREAREELGLSLGELASELGVSRRTISKYENGGM-NASI 168
VapI COG3093
Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense ...
3-62 7.05e-04

Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense mechanisms];


Pssm-ID: 442327 [Multi-domain]  Cd Length: 87  Bit Score: 35.56  E-value: 7.05e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446501024   3 GERIKRLRLQ-KGISLTELAEKAGVAKSYISSIERNlQKNPSIQFLEKIAAVLQIPVDTLL 62
Cdd:COG3093   10 GEILREEFLEpLGLSQTELAKALGVSRQRISEILNG-KRAITADTALRLARAFGTSAEFWL 69
PRK08099 PRK08099
multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase ...
12-56 1.41e-03

multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR;


Pssm-ID: 236151 [Multi-domain]  Cd Length: 399  Bit Score: 36.17  E-value: 1.41e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 446501024  12 QKGISLTELAEKAGVAKSYISSIERNLQKNPSIQFLEKIAAVLQI 56
Cdd:PRK08099   1 QQGCTLQQVADASGMTKGYLSQLLNAKIKSPSAQKLEALHRFLGL 45
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
3-74 4.06e-03

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 35.10  E-value: 4.06e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446501024   3 GERIKRLRLQKGIS---LTELAEKAG--VAKSYISSIERNlqKN-PSIQFLEKIAAVLQIPVDTLLHDETTKEANLDS 74
Cdd:PRK13355   5 AERLKQAMKARGLKqedLVHAAEARGvkLGKSHISQYVSG--KTgPRRDVLPFLAAILGVSEDWLLGGESPADQESDA 80
LexA COG1974
SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, ...
1-58 7.87e-03

SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) [Transcription, Signal transduction mechanisms];


Pssm-ID: 441577 [Multi-domain]  Cd Length: 199  Bit Score: 34.12  E-value: 7.87e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446501024   1 MIGERIKRLRLQKGISLT--ELAEKAGVAKSYISS----------IERNLQKNPSIQFLEKIAAVLQIPV 58
Cdd:COG1974   10 EILDFIKEYIRERGYPPSqrEIAEALGLSSSAVHRhlkalekkgyLRRDPGKSRAIELLPASPEVVGLPL 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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