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Conserved domains on  [gi|446514237|ref|WP_000591583|]
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MULTISPECIES: glycine betaine transporter OpuD [Bacillus]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
3-499 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 608.68  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   3 KKENSVFYISILLTTLFIIWGIT-PASwiqgydLQSVTSSLNSFILNKFGWFYSLLMTAMIILAAYLAFSKYGSIRLGKD 81
Cdd:COG1292   12 KIDPPVFIPSALLILAFVLWGLLfPEA------AGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGD 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  82 GEKPKYSYPSWLSMLFGAGMGIGLLFYGIAEPISHFTDPLTG-KAGTEESAKLAMQYSFFHWGLFPWSLYAMVALTIAYF 160
Cdd:COG1292   86 DAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALAYF 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 161 TFRKQKGSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIGAQQIAGGLSYLFpSIHNTLFTQLILIAIFAV 240
Cdd:COG1292  166 AYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLF-GIPNSLTVQIIIIAVITA 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 241 LYLTSAQTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTLGSYIGALPSMGLNLGAFNEksSSWIENWTIF 320
Cdd:COG1292  245 LFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGGWTVF 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 321 YWGWWISWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGGTAIHMEMFQSLGIAdEIAKNGTEIGLFAVIS 400
Cdd:COG1292  323 YWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLA-EAVAAGVEAALFALLE 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 401 HLPFSTFLTIIGLILVATFFVTSADSATFVVSMQTSNGSLSPKNSLKLIWGLTIAIIAAILLQAGGLNALQIAAIIAALP 480
Cdd:COG1292  402 QLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALP 481
                        490
                 ....*....|....*....
gi 446514237 481 FSIVVVLMVTSLFKELRKE 499
Cdd:COG1292  482 FSFVLLLMCVSLVKALRED 500
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
3-499 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 608.68  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   3 KKENSVFYISILLTTLFIIWGIT-PASwiqgydLQSVTSSLNSFILNKFGWFYSLLMTAMIILAAYLAFSKYGSIRLGKD 81
Cdd:COG1292   12 KIDPPVFIPSALLILAFVLWGLLfPEA------AGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGD 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  82 GEKPKYSYPSWLSMLFGAGMGIGLLFYGIAEPISHFTDPLTG-KAGTEESAKLAMQYSFFHWGLFPWSLYAMVALTIAYF 160
Cdd:COG1292   86 DAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALAYF 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 161 TFRKQKGSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIGAQQIAGGLSYLFpSIHNTLFTQLILIAIFAV 240
Cdd:COG1292  166 AYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLF-GIPNSLTVQIIIIAVITA 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 241 LYLTSAQTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTLGSYIGALPSMGLNLGAFNEksSSWIENWTIF 320
Cdd:COG1292  245 LFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGGWTVF 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 321 YWGWWISWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGGTAIHMEMFQSLGIAdEIAKNGTEIGLFAVIS 400
Cdd:COG1292  323 YWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLA-EAVAAGVEAALFALLE 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 401 HLPFSTFLTIIGLILVATFFVTSADSATFVVSMQTSNGSLSPKNSLKLIWGLTIAIIAAILLQAGGLNALQIAAIIAALP 480
Cdd:COG1292  402 QLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALP 481
                        490
                 ....*....|....*....
gi 446514237 481 FSIVVVLMVTSLFKELRKE 499
Cdd:COG1292  482 FSFVLLLMCVSLVKALRED 500
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
8-499 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 594.52  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237    8 VFYISILLTTLFIIWGItpaswIQGYDLQSVTSSLNSFILNKFGWFYSLLMTAMIILAAYLAFSKYGSIRLGKDGEKPKY 87
Cdd:pfam02028   1 VFAVSAGLILAFVLLGL-----IFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEF 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   88 SYPSWLSMLFGAGMGIGLLFYGIAEPISHFTD-PLTGKAGTEESAKLAMQYSFFHWGLFPWSLYAMVALTIAYFTFRKQK 166
Cdd:pfam02028  76 STFSWFAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGL 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  167 GSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIGAQQIAGGLSYLFpSIHNTLFTQLILIAIFAVLYLTSA 246
Cdd:pfam02028 156 PLLISSALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLF-GIPNTLTTQLAIIAIITALFTISA 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  247 QTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTLGSYIGALPSMGLNLGAFnEKSSSWIENWTIFYWGWWI 326
Cdd:pfam02028 235 VSGLDKGIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPF-GDTGGWLGGWTIFYWAWWI 313
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  327 SWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGGTAIHMEMFQSLGIADeIAKNGTEIGLFAVISHLPFST 406
Cdd:pfam02028 314 AWAPFVGMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGDLAD-AVEAGPPAALFALLEQLPLGT 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  407 FLTIIGLILVATFFVTSADSATFVVSMQTSNGSLSPKNSLKLIWGLTIAIIAAILLQAGGLNALQIAAIIAALPFSIVVV 486
Cdd:pfam02028 393 ILSVLALLLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILL 472
                         490
                  ....*....|...
gi 446514237  487 LMVTSLFKELRKE 499
Cdd:pfam02028 473 LMCISLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
51-499 1.18e-140

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 412.90  E-value: 1.18e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   51 GWFYSLLMTAMIILAAYLAFSKYGSIRLGKDGEKPKYSYPSWLSMLFGAGMGIGLLFYGIAEPISHFTDPLTGKAGTEES 130
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  131 AK-LAMQYSFFHWGLFPWSLYAMVALTIAYFTFRKQKGSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIG 209
Cdd:TIGR00842  81 AQeQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  210 AQQIAGGLSYLFpSIHNTLFTQLILIAIFAVLYLTSAQTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTL 289
Cdd:TIGR00842 161 APQINAGLSALF-GIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  290 GSYIGALPSMGLNLGAFNEKSSsWIENWTIFYWGWWISWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGG 369
Cdd:TIGR00842 240 GNYLQNFPQMSFRTDPDDGKGG-WPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGN 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  370 TAIHMEMFQSLGIADEIAKNGTEIGLFAVISHLPFSTFLTIIGLILVATFFVTSADSATFVV-SMQTSNGSL--SPKNSL 446
Cdd:TIGR00842 319 SALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLaNTTSRGGQLgeEPPKWV 398
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 446514237  447 KLIWGLTIAIIAAILLQAGG-LNALQIAAIIAALPFSIVVVLMVTSLFKELRKE 499
Cdd:TIGR00842 399 RVFWAVAIGLIALVLLFSGGsLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
8-500 7.99e-133

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 400.61  E-value: 7.99e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   8 VFYISILLTTLFIIWGI----TPASWIqgydlqsvTSSLNsFILNKFGWFYSLLMTAMIILAAYLAFSKYGSIRLGKDGE 83
Cdd:PRK09928  19 VFYTSAGLILLFSLTTIlftdFSNRWI--------NRTLN-WVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQS 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  84 KPKYSYPSWLSMLFGAGMGIGLLFYGIAEPISHFTDPLTGKAGTEESAKLAMQYSFFHWGLFPWSLYAMVALTIAYFTFR 163
Cdd:PRK09928  90 KPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYR 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 164 KQKGSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIGAQQIAGGLSYLFpSIHNTLFTQLILIAIFAVLYL 243
Cdd:PRK09928 170 YNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLF-DIPESLAAQAALIALSVIIAT 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 244 TSAQTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTLGSYIGALPSMGLNLGAFnEKSSSWIENWTIFYWG 323
Cdd:PRK09928 249 ISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAF-DRPTEWMNNWTLFFWA 327
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 324 WWISWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGGTAIHMEMFQSLGIADEIAKNgTEIGLFAVISHLP 403
Cdd:PRK09928 328 WWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAAFAEEAMAH-PERGFYSLLAQYP 406
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 404 FSTFLTIIGLILVATFFVTSADSATFVVSMQTSNgsLSPKNS-----LKLIWGLTIAIIAAILLQAGGLNALQIAAIIAA 478
Cdd:PRK09928 407 AFTFSASVATITGLLFYVTSADSGALVLGNFTSK--LKDINSdapnwLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMG 484
                        490       500
                 ....*....|....*....|..
gi 446514237 479 LPFSIVVVLMVTSLFKELRKED 500
Cdd:PRK09928 485 LPFSFVIFFVMAGLYKSLKVED 506
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
3-499 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 608.68  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   3 KKENSVFYISILLTTLFIIWGIT-PASwiqgydLQSVTSSLNSFILNKFGWFYSLLMTAMIILAAYLAFSKYGSIRLGKD 81
Cdd:COG1292   12 KIDPPVFIPSALLILAFVLWGLLfPEA------AGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGD 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  82 GEKPKYSYPSWLSMLFGAGMGIGLLFYGIAEPISHFTDPLTG-KAGTEESAKLAMQYSFFHWGLFPWSLYAMVALTIAYF 160
Cdd:COG1292   86 DAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALAYF 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 161 TFRKQKGSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIGAQQIAGGLSYLFpSIHNTLFTQLILIAIFAV 240
Cdd:COG1292  166 AYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLF-GIPNSLTVQIIIIAVITA 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 241 LYLTSAQTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTLGSYIGALPSMGLNLGAFNEksSSWIENWTIF 320
Cdd:COG1292  245 LFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGGWTVF 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 321 YWGWWISWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGGTAIHMEMFQSLGIAdEIAKNGTEIGLFAVIS 400
Cdd:COG1292  323 YWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLA-EAVAAGVEAALFALLE 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 401 HLPFSTFLTIIGLILVATFFVTSADSATFVVSMQTSNGSLSPKNSLKLIWGLTIAIIAAILLQAGGLNALQIAAIIAALP 480
Cdd:COG1292  402 QLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALP 481
                        490
                 ....*....|....*....
gi 446514237 481 FSIVVVLMVTSLFKELRKE 499
Cdd:COG1292  482 FSFVLLLMCVSLVKALRED 500
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
8-499 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 594.52  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237    8 VFYISILLTTLFIIWGItpaswIQGYDLQSVTSSLNSFILNKFGWFYSLLMTAMIILAAYLAFSKYGSIRLGKDGEKPKY 87
Cdd:pfam02028   1 VFAVSAGLILAFVLLGL-----IFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEF 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   88 SYPSWLSMLFGAGMGIGLLFYGIAEPISHFTD-PLTGKAGTEESAKLAMQYSFFHWGLFPWSLYAMVALTIAYFTFRKQK 166
Cdd:pfam02028  76 STFSWFAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGL 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  167 GSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIGAQQIAGGLSYLFpSIHNTLFTQLILIAIFAVLYLTSA 246
Cdd:pfam02028 156 PLLISSALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLF-GIPNTLTTQLAIIAIITALFTISA 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  247 QTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTLGSYIGALPSMGLNLGAFnEKSSSWIENWTIFYWGWWI 326
Cdd:pfam02028 235 VSGLDKGIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPF-GDTGGWLGGWTIFYWAWWI 313
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  327 SWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGGTAIHMEMFQSLGIADeIAKNGTEIGLFAVISHLPFST 406
Cdd:pfam02028 314 AWAPFVGMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGDLAD-AVEAGPPAALFALLEQLPLGT 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  407 FLTIIGLILVATFFVTSADSATFVVSMQTSNGSLSPKNSLKLIWGLTIAIIAAILLQAGGLNALQIAAIIAALPFSIVVV 486
Cdd:pfam02028 393 ILSVLALLLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILL 472
                         490
                  ....*....|...
gi 446514237  487 LMVTSLFKELRKE 499
Cdd:pfam02028 473 LMCISLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
51-499 1.18e-140

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 412.90  E-value: 1.18e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   51 GWFYSLLMTAMIILAAYLAFSKYGSIRLGKDGEKPKYSYPSWLSMLFGAGMGIGLLFYGIAEPISHFTDPLTGKAGTEES 130
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  131 AK-LAMQYSFFHWGLFPWSLYAMVALTIAYFTFRKQKGSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIG 209
Cdd:TIGR00842  81 AQeQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  210 AQQIAGGLSYLFpSIHNTLFTQLILIAIFAVLYLTSAQTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTL 289
Cdd:TIGR00842 161 APQINAGLSALF-GIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  290 GSYIGALPSMGLNLGAFNEKSSsWIENWTIFYWGWWISWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGG 369
Cdd:TIGR00842 240 GNYLQNFPQMSFRTDPDDGKGG-WPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGN 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  370 TAIHMEMFQSLGIADEIAKNGTEIGLFAVISHLPFSTFLTIIGLILVATFFVTSADSATFVV-SMQTSNGSL--SPKNSL 446
Cdd:TIGR00842 319 SALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLaNTTSRGGQLgeEPPKWV 398
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 446514237  447 KLIWGLTIAIIAAILLQAGG-LNALQIAAIIAALPFSIVVVLMVTSLFKELRKE 499
Cdd:TIGR00842 399 RVFWAVAIGLIALVLLFSGGsLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
8-500 7.99e-133

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 400.61  E-value: 7.99e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   8 VFYISILLTTLFIIWGI----TPASWIqgydlqsvTSSLNsFILNKFGWFYSLLMTAMIILAAYLAFSKYGSIRLGKDGE 83
Cdd:PRK09928  19 VFYTSAGLILLFSLTTIlftdFSNRWI--------NRTLN-WVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQS 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  84 KPKYSYPSWLSMLFGAGMGIGLLFYGIAEPISHFTDPLTGKAGTEESAKLAMQYSFFHWGLFPWSLYAMVALTIAYFTFR 163
Cdd:PRK09928  90 KPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYR 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 164 KQKGSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIGAQQIAGGLSYLFpSIHNTLFTQLILIAIFAVLYL 243
Cdd:PRK09928 170 YNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLF-DIPESLAAQAALIALSVIIAT 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 244 TSAQTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTLGSYIGALPSMGLNLGAFnEKSSSWIENWTIFYWG 323
Cdd:PRK09928 249 ISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAF-DRPTEWMNNWTLFFWA 327
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 324 WWISWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGGTAIHMEMFQSLGIADEIAKNgTEIGLFAVISHLP 403
Cdd:PRK09928 328 WWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAAFAEEAMAH-PERGFYSLLAQYP 406
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 404 FSTFLTIIGLILVATFFVTSADSATFVVSMQTSNgsLSPKNS-----LKLIWGLTIAIIAAILLQAGGLNALQIAAIIAA 478
Cdd:PRK09928 407 AFTFSASVATITGLLFYVTSADSGALVLGNFTSK--LKDINSdapnwLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMG 484
                        490       500
                 ....*....|....*....|..
gi 446514237 479 LPFSIVVVLMVTSLFKELRKED 500
Cdd:PRK09928 485 LPFSFVIFFVMAGLYKSLKVED 506
PRK09950 PRK09950
putative transporter; Provisional
3-499 1.27e-70

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 233.91  E-value: 1.27e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237   3 KKENSVFYISILLTTLFIIwGITPASWIQgyDLQSVTSSLNSFILNKFGWFYSLLMTAMIILAAYLAFSKYGSIRLGKDg 82
Cdd:PRK09950   5 KKKKDKPLISTSLLAVFFI-VAALSLFPQ--QSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLGEG- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  83 eKPKYSYPSWLSMLFGAGMGIGLLFYGIAEPISHFTDP-LTGKAGTEESAKLAMQYSFFHWGLFPWSLYAMVALTIAY-F 160
Cdd:PRK09950  81 -KPEYSTLSWLFMFICAGLGSSTLYWGVMEWAYYYQTPgLNIAPRSPKALEYSVSYSFFHWGISAWATYALASLIMAYhF 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 161 TFRKQKGSTIGATVTPLFNRSKNSPIGKTVDILAVLATVFGIVPSVGIGAQQIAGGLSYLFpSIHNTLFTQLILIAIFAV 240
Cdd:PRK09950 160 HVRKNKGLSLSGIIAAITGVKPQGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALT-GLPNNFTVQAFVILLSGV 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 241 LYLTSAQTGLDRGIKYLSNLNFSLAGILLISFLLLGPTVFIMKYFTSTLGSYIGALPSMGLNLGAFNEksSSWIENWTIF 320
Cdd:PRK09950 239 IFCLSSYIGIDNGLQRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFLQMSLFTDPMGD--GSFTRNWTVF 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 321 YWGWWISWSPFVGTFIARISKGRTIKEFIFGVVLVPTLICTFWFAVFGGTAIHMEMFQSLGIADEIAKNGTEIGLFAVIS 400
Cdd:PRK09950 317 YWLWWISYTPGVAMFVTRVSRGRKIKEVIWGLILGSSVGCWFFFGVLESYAIHQFINGVINVPQILNTLGGETAVQQLLS 396
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 401 HLPFSTFLTIIGLILVATFFVTSADSATFVVSmQTSNGSLS----PKNSLKLIWGLTIAIIA-AILLQAGGLNALQIAAI 475
Cdd:PRK09950 397 SLPAGKLFLAAYLGIMIIFLASHMDAVAYTMA-ATSTRNLRegddPDRGLRLFWCVVITLIPlSILFTGASLDTMKTTVV 475
                        490       500
                 ....*....|....*....|....
gi 446514237 476 IAALPFSIVVVLMVTSLFKELRKE 499
Cdd:PRK09950 476 LTALPFLVILLIKVYGFIRWLKQD 499
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
38-498 2.63e-70

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 233.09  E-value: 2.63e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237  38 VTSSLNSFILNKFGWFYSLLMTAMIILAAYLAFSKYGSIRLGKdgEKPKYSYPSWLSMLFGAGMGIGLLFYGIAEPISHF 117
Cdd:PRK03356  39 VINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGD--EKPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYI 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 118 TDPLTG-KAGTEESAKLAMQYSFFHWGLFPWSLYAMVALTIAYFTF-RKQKGSTIGATVTPLF-NRSKNSPIGKTVDILA 194
Cdd:PRK03356 117 STPPFGlEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFFFvRKMDVIRPSSTLVPLVgEKHAKGLFGTIVDNFY 196
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 195 VLATVFGIVPSVGIGAQQIAGGLSYLFpSIHNTLFTQLILIAIFAVLYLTSAQTGLDRGIKYLSNLNFSLAGILLISFLL 274
Cdd:PRK03356 197 LVALIFAMGTSLGLATPLVTECMQWLF-GIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFI 275
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 275 LGPTVFIMKYFTSTLGSYIGALPSMGLNLGAFNEksSSWIENWTIFYWGWWISWSPFVGTFIARISKGRTIKEFIFGVVL 354
Cdd:PRK03356 276 VGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPIGK--GGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVL 353
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446514237 355 VPTLICTFWFAVFGGTAIHMEMFQSLGIADEIAKNGTEIGLFAVISHLPFSTFLTIIGLILVATFFVTSADSATFVVSMQ 434
Cdd:PRK03356 354 GLTASTWILWTVLGSNTLLLMDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLINACSYTLAMS 433
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446514237 435 TSNGSLS---PKNSLKLIWGLTIAIIAAILLQAGGLNALQIAAIIAALPFSIVVVLMVTSLFKELRK 498
Cdd:PRK03356 434 TCREVRDgeePPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQ 500
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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