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Conserved domains on  [gi|446517235|ref|WP_000594581|]
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type II secretion system minor pseudopilin GspJ [Acinetobacter baumannii]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 22-136 1.10e-22

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 88.92  E-value: 1.10e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235  22 SARLTRVSGFTLVELLVAIAIFAVLSLLGWKIFDYLLKVRDRNAEHEVHLFELQDAYQQILRDTLQIIPlSANQGGQLHP 101
Cdd:COG4795    2 KRARRRQRGFTLLELLVALAIFALLLLAAYRGLDSVLRSRERLEQQAERLQELQRALALLERDLRQAGP-RPDEGGDPEP 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446517235 102 ALEIDNQ-ILRFSKAGVTDPLKQGLspfERIEYRYD 136
Cdd:COG4795   81 ALSGGGScLIDLNRNGWWNPLRSEL---QRVGYRLR 113
T2SSJ pfam11612
Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are ...
 83-212 1.51e-15

Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are targeted to the membrane in E. Coli. T2SJ forms a complex with T2SI (pfam02501) and T2SK (pfam03934) which is part of the Type II secretion apparatus involved in the translocation of proteins across the outer membrane in E.coli. The T2SK-I-J complex has quasihelical characteriztics.


:

Pssm-ID: 431959  Cd Length: 137  Bit Score: 70.82  E-value: 1.51e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235   83 RDTLQIIPLSA-NQGGQLHPAL-----EIDNQILRFSKAGVTDPLKQGLSPFERIEYRYdaDQKKLYRLKYTNLNTSNRE 156
Cdd:pfam11612   3 RDLSQAVPRPVrDAGGDPAPAFagrglDSDDPGLEFTRLGWPNPDGAPRSELQRVGYRL--EDGRLERLTWPYLDGAVGQ 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 446517235  157 QPLSSTLLSQVDQYQIMVLTP-QEVTKWPEVNIDPtkpnelkKLPKGIKIQLTVAGV 212
Cdd:pfam11612  81 EPQVQVLLDGVESLRLRFLDDgQWQDRWPPAAADQ-------ALPRAVEITLELKDG 130
 
Name Accession Description Interval E-value
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 22-136 1.10e-22

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 88.92  E-value: 1.10e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235  22 SARLTRVSGFTLVELLVAIAIFAVLSLLGWKIFDYLLKVRDRNAEHEVHLFELQDAYQQILRDTLQIIPlSANQGGQLHP 101
Cdd:COG4795    2 KRARRRQRGFTLLELLVALAIFALLLLAAYRGLDSVLRSRERLEQQAERLQELQRALALLERDLRQAGP-RPDEGGDPEP 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446517235 102 ALEIDNQ-ILRFSKAGVTDPLKQGLspfERIEYRYD 136
Cdd:COG4795   81 ALSGGGScLIDLNRNGWWNPLRSEL---QRVGYRLR 113
gspJ TIGR01711
type II secretion system protein J; This model represents GspJ, one of two proteins highly ...
 30-207 4.73e-16

type II secretion system protein J; This model represents GspJ, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspI. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 130772 [Multi-domain]  Cd Length: 192  Bit Score: 73.41  E-value: 4.73e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235   30 GFTLVELLVAIAIFAVLSLLGWKIFDYLLKVRDRNAEHEVHLFELQDAYQQILRDTLQIIPLSANQGGQLHPAL------ 103
Cdd:TIGR01711   2 GFTLLELLVAIAIFASLSLGAYQVLDSVMQSDEATRVQEARLRELQRAMGAMERDLTQMVERPVRDDGEASEQDlrgafl 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235  104 --EIDNQILRFSKAGVTDPlkQGLSPFERIE-YRYDADQKKLYRLKYTNLNTSNREQPLSSTLLSQVDQYQIMVLTPQEV 180
Cdd:TIGR01711  82 seGSDDQGVEFTRGGWRNP--LGQQPRSRLQrVGWRLSGETLERRYWLYPDRAQGSKPRIQPVLDGVTALSWRFYDKGNW 159

                         170       180
                  ....*....|....*....|....*...
gi 446517235  181 TK-WPEVNIdptkpnelkkLPKGIKIQL 207
Cdd:TIGR01711 160 QGeWPTDNS----------LPLAVEVTL 177
T2SSJ pfam11612
Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are ...
 83-212 1.51e-15

Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are targeted to the membrane in E. Coli. T2SJ forms a complex with T2SI (pfam02501) and T2SK (pfam03934) which is part of the Type II secretion apparatus involved in the translocation of proteins across the outer membrane in E.coli. The T2SK-I-J complex has quasihelical characteriztics.


Pssm-ID: 431959  Cd Length: 137  Bit Score: 70.82  E-value: 1.51e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235   83 RDTLQIIPLSA-NQGGQLHPAL-----EIDNQILRFSKAGVTDPLKQGLSPFERIEYRYdaDQKKLYRLKYTNLNTSNRE 156
Cdd:pfam11612   3 RDLSQAVPRPVrDAGGDPAPAFagrglDSDDPGLEFTRLGWPNPDGAPRSELQRVGYRL--EDGRLERLTWPYLDGAVGQ 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 446517235  157 QPLSSTLLSQVDQYQIMVLTP-QEVTKWPEVNIDPtkpnelkKLPKGIKIQLTVAGV 212
Cdd:pfam11612  81 EPQVQVLLDGVESLRLRFLDDgQWQDRWPPAAADQ-------ALPRAVEITLELKDG 130
N_methyl pfam07963
Prokaryotic N-terminal methylation motif; This short motif directs methylation of the ...
 27-49 7.16e-06

Prokaryotic N-terminal methylation motif; This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.


Pssm-ID: 429756 [Multi-domain]  Cd Length: 27  Bit Score: 41.59  E-value: 7.16e-06
                          10        20
                  ....*....|....*....|...
gi 446517235   27 RVSGFTLVELLVAIAIFAVLSLL 49
Cdd:pfam07963   3 KQRGFTLIELLVALAILAILLAA 25
PRK10574 PRK10574
putative major pilin subunit; Provisional
 25-50 9.75e-05

putative major pilin subunit; Provisional


Pssm-ID: 236718 [Multi-domain]  Cd Length: 146  Bit Score: 41.17  E-value: 9.75e-05
                         10        20
                 ....*....|....*....|....*.
gi 446517235  25 LTRVSGFTLVELLVAIAIFAVLSLLG 50
Cdd:PRK10574   1 MDKQRGFTLIELMVVIAIIAILSAIG 26
 
Name Accession Description Interval E-value
PulJ COG4795
Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and ...
 22-136 1.10e-22

Type II secretory pathway, PulJ/GspJ component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443823 [Multi-domain]  Cd Length: 118  Bit Score: 88.92  E-value: 1.10e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235  22 SARLTRVSGFTLVELLVAIAIFAVLSLLGWKIFDYLLKVRDRNAEHEVHLFELQDAYQQILRDTLQIIPlSANQGGQLHP 101
Cdd:COG4795    2 KRARRRQRGFTLLELLVALAIFALLLLAAYRGLDSVLRSRERLEQQAERLQELQRALALLERDLRQAGP-RPDEGGDPEP 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446517235 102 ALEIDNQ-ILRFSKAGVTDPLKQGLspfERIEYRYD 136
Cdd:COG4795   81 ALSGGGScLIDLNRNGWWNPLRSEL---QRVGYRLR 113
gspJ TIGR01711
type II secretion system protein J; This model represents GspJ, one of two proteins highly ...
 30-207 4.73e-16

type II secretion system protein J; This model represents GspJ, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspI. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 130772 [Multi-domain]  Cd Length: 192  Bit Score: 73.41  E-value: 4.73e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235   30 GFTLVELLVAIAIFAVLSLLGWKIFDYLLKVRDRNAEHEVHLFELQDAYQQILRDTLQIIPLSANQGGQLHPAL------ 103
Cdd:TIGR01711   2 GFTLLELLVAIAIFASLSLGAYQVLDSVMQSDEATRVQEARLRELQRAMGAMERDLTQMVERPVRDDGEASEQDlrgafl 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235  104 --EIDNQILRFSKAGVTDPlkQGLSPFERIE-YRYDADQKKLYRLKYTNLNTSNREQPLSSTLLSQVDQYQIMVLTPQEV 180
Cdd:TIGR01711  82 seGSDDQGVEFTRGGWRNP--LGQQPRSRLQrVGWRLSGETLERRYWLYPDRAQGSKPRIQPVLDGVTALSWRFYDKGNW 159

                         170       180
                  ....*....|....*....|....*...
gi 446517235  181 TK-WPEVNIdptkpnelkkLPKGIKIQL 207
Cdd:TIGR01711 160 QGeWPTDNS----------LPLAVEVTL 177
T2SSJ pfam11612
Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are ...
 83-212 1.51e-15

Type II secretion system (T2SS), protein J; The T2SJ proteins are pseudopilins, which are targeted to the membrane in E. Coli. T2SJ forms a complex with T2SI (pfam02501) and T2SK (pfam03934) which is part of the Type II secretion apparatus involved in the translocation of proteins across the outer membrane in E.coli. The T2SK-I-J complex has quasihelical characteriztics.


Pssm-ID: 431959  Cd Length: 137  Bit Score: 70.82  E-value: 1.51e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235   83 RDTLQIIPLSA-NQGGQLHPAL-----EIDNQILRFSKAGVTDPLKQGLSPFERIEYRYdaDQKKLYRLKYTNLNTSNRE 156
Cdd:pfam11612   3 RDLSQAVPRPVrDAGGDPAPAFagrglDSDDPGLEFTRLGWPNPDGAPRSELQRVGYRL--EDGRLERLTWPYLDGAVGQ 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 446517235  157 QPLSSTLLSQVDQYQIMVLTP-QEVTKWPEVNIDPtkpnelkKLPKGIKIQLTVAGV 212
Cdd:pfam11612  81 EPQVQVLLDGVESLRLRFLDDgQWQDRWPPAAADQ-------ALPRAVEITLELKDG 130
PulG COG2165
Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, ...
 20-85 4.49e-08

Type II secretory pathway, pseudopilin PulG [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 441768 [Multi-domain]  Cd Length: 99  Bit Score: 49.53  E-value: 4.49e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446517235  20 SSSARLTRVSGFTLVELLVAIAIFAVLSLLGWKIFDYLLKvRDRNAEHEVHLFELQDAYQQILRDT 85
Cdd:COG2165    2 KLRRRRRRQRGFTLIELLVVIAIIGILAALALPALQGARE-RARRAELRSNLRQIQQALERYRLDN 66
PilE COG4968
Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];
22-80 5.56e-07

Type IV pilus assembly protein PilE [Cell motility, Extracellular structures];


Pssm-ID: 443994 [Multi-domain]  Cd Length: 124  Bit Score: 46.99  E-value: 5.56e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446517235  22 SARLTRVSGFTLVELLVAIAIFAVLSLLGWKIF-DYLLKVRDRNAEHEvhLFELQDAYQQ 80
Cdd:COG4968    3 KRMRRRQRGFTLIELMIVVAIIGILAAIAIPSYqDYVERARRAEAKAA--LLELAQAQER 60
N_methyl pfam07963
Prokaryotic N-terminal methylation motif; This short motif directs methylation of the ...
 27-49 7.16e-06

Prokaryotic N-terminal methylation motif; This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.


Pssm-ID: 429756 [Multi-domain]  Cd Length: 27  Bit Score: 41.59  E-value: 7.16e-06
                          10        20
                  ....*....|....*....|...
gi 446517235   27 RVSGFTLVELLVAIAIFAVLSLL 49
Cdd:pfam07963   3 KQRGFTLIELLVALAILAILLAA 25
FimT COG4970
Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];
27-51 2.30e-05

Type IV pilus assembly protein FimT [Cell motility, Extracellular structures];


Pssm-ID: 443996 [Multi-domain]  Cd Length: 73  Bit Score: 41.37  E-value: 2.30e-05
                         10        20
                 ....*....|....*....|....*
gi 446517235  27 RVSGFTLVELLVAIAIFAVLSLLGW 51
Cdd:COG4970    7 RQRGFTLIELLVVLAILAILAAIAV 31
IV_pilin_GFxxxE TIGR02532
prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all ...
 29-50 3.80e-05

prepilin-type N-terminal cleavage/methylation domain; This model describes many but not all examples of the N-terminal region of bacterial proteins that resemble type IV pilins at their N-terminus, with a cleavage site G^FxxxE followed by a hydrophobic stretch. The new N-terminal residue, usually Phe, is methylated. Separate domains of the prepilin peptidase appear responsible for cleavage and methylation. Proteins with this N-terminal region include type IV pilins and other components of pilus biogenesis, competence proteins, and type II secretion proteins. Typically several proteins in a single operon have this N-terminal domain. The N-terminal cleavage and methylation site is described by PROSITE motif PS00409 as [KRHEQSTAG]-G-[FYLIVM]-[ST]-[LT]-[LIVP]-E-[LIVMFWSTAG](14). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274182 [Multi-domain]  Cd Length: 24  Bit Score: 39.60  E-value: 3.80e-05
                          10        20
                  ....*....|....*....|..
gi 446517235   29 SGFTLVELLVAIAIFAVLSLLG 50
Cdd:TIGR02532   2 RGFTLIELLVVLAILGILALIA 23
PRK10574 PRK10574
putative major pilin subunit; Provisional
 25-50 9.75e-05

putative major pilin subunit; Provisional


Pssm-ID: 236718 [Multi-domain]  Cd Length: 146  Bit Score: 41.17  E-value: 9.75e-05
                         10        20
                 ....*....|....*....|....*.
gi 446517235  25 LTRVSGFTLVELLVAIAIFAVLSLLG 50
Cdd:PRK10574   1 MDKQRGFTLIELMVVIAIIAILSAIG 26
PilV COG4967
Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];
20-50 3.45e-04

Type IV pilus assembly protein PilV [Cell motility, Extracellular structures];


Pssm-ID: 443993 [Multi-domain]  Cd Length: 86  Bit Score: 38.43  E-value: 3.45e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 446517235  20 SSSARLTRVSGFTLVELLVAIAIFAV--LSLLG 50
Cdd:COG4967    2 SRRRRRRRQRGFTLIEVLVALVILSIglLGLAG 34
PilA COG4969
Type IV pilus assembly protein, major pilin PilA [Cell motility, Extracellular structures];
29-47 1.61e-03

Type IV pilus assembly protein, major pilin PilA [Cell motility, Extracellular structures];


Pssm-ID: 443995 [Multi-domain]  Cd Length: 134  Bit Score: 37.38  E-value: 1.61e-03
                         10
                 ....*....|....*....
gi 446517235  29 SGFTLVELLVAIAIFAVLS 47
Cdd:COG4969    6 KGFTLIELMIVVAIIGILA 24
PRK10506 PRK10506
prepilin peptidase-dependent protein;
29-72 5.32e-03

prepilin peptidase-dependent protein;


Pssm-ID: 236704 [Multi-domain]  Cd Length: 162  Bit Score: 36.51  E-value: 5.32e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446517235  29 SGFTLVELLVAIAIFAVLSLLGW-----------------KIFDYLLKVRD----RNAEHEVHLF 72
Cdd:PRK10506   9 RGYTLIELLVVMTIVSILSAWGLygwqrwqqrqrlwqtaqQLLDFLLRLQEdanwHNRDHILWLI 73
PilW COG4966
Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];
29-48 5.59e-03

Type IV pilus assembly protein PilW [Cell motility, Extracellular structures];


Pssm-ID: 443992 [Multi-domain]  Cd Length: 158  Bit Score: 36.31  E-value: 5.59e-03
                         10        20
                 ....*....|....*....|
gi 446517235  29 SGFTLVELLVAIAIFAVLSL 48
Cdd:COG4966    5 RGFTLVELMVALAIGLIVLA 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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