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Conserved domains on  [gi|446531759|ref|WP_000609105|]
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MULTISPECIES: ABC transporter ATP-binding protein [Bacillus]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11438980)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ABC transporter complex responsible for coupling the energy of ATP hydrolysis to the transport of one or more from a variety of substrates including hemin, bacitracin, and lipoproteins

CATH:  3.40.50.300
EC:  7.6.2.-
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-221 9.87e-135

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 377.46  E-value: 9.87e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG1136    4 LLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG1136   84 RRRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:COG1136  164 KLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPELAARADRVIRLRDGRIVSD 225
 
Name Accession Description Interval E-value
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-221 9.87e-135

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 377.46  E-value: 9.87e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG1136    4 LLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG1136   84 RRRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:COG1136  164 KLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPELAARADRVIRLRDGRIVSD 225
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
2-218 1.38e-124

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 351.41  E-value: 1.38e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVR 81
Cdd:cd03255    1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03255   81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIVIRDGNI 218
Cdd:cd03255  161 IILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDPELAEYADRIIELRDGKI 218
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
1-221 4.01e-90

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 277.76  E-value: 4.01e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:PRK10535   4 LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:PRK10535  84 RREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGG 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:PRK10535 164 QVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRN 224
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
1-216 6.53e-76

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 227.90  E-value: 6.53e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    1 MINLKGITKSFQNGaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:TIGR02673   1 MIEFHNVSKAYPGG---VAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLPLL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   81 RNKeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:TIGR02673  78 RRR-IGVVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSP 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759  161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEA-AARQIVIRDG 216
Cdd:TIGR02673 157 PLLLADEPTGNLDPDLSERILDLLKRLNKRGTTVIVATHDLSLVDRvAHRVIILDDG 213
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
21-169 1.99e-44

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 145.48  E-value: 1.99e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTEtelaRVRNKEIGFVFQNFMLLPRLTA 100
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDER----KSLRKEIGYVFQDPQLFPRLTV 76
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759  101 LQNVELPLIYAGVDKKERRERSLAALTKVGLAD----RATHLPNELSGGQKQRVAVARAIVNNPKFILADEPT 169
Cdd:pfam00005  77 RENLRLGLLLKGLSKREKDARAEEALEKLGLGDladrPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
14-213 7.57e-34

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 119.65  E-value: 7.57e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  14 GAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTyelagqnisnmteteLARVRNKEIGFVFQNFM 93
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGT---------------VRRAGGARVAYVPQRSE 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  94 L---LPrLTALQNVEL----PLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILAD 166
Cdd:NF040873  66 VpdsLP-LTVRDLVAMgrwaRRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLD 144
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 446531759 167 EPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVI 213
Cdd:NF040873 145 EPTTGLDAESRERIIALLAEEHARGATVVVVTHDLELVRRADPCVLL 191
GguA NF040905
sugar ABC transporter ATP-binding protein;
4-220 3.53e-21

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 91.00  E-value: 3.53e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLdKPTtGTYElaGQNISNMTETELARVRNK 83
Cdd:NF040905   4 MRGITKTFPG----VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV-YPH-GSYE--GEILFDGEVCRFKDIRDS 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 E---IGFVFQNFMLLPRLTALQNVEL---PLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIV 157
Cdd:NF040905  76 EalgIVIIHQELALIPYLSIAENIFLgneRAKRGVIDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALS 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIVQ 220
Cdd:NF040905 156 KDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKlNEIRRVADSITVLRDGRTIE 219
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
30-199 7.17e-12

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 63.99  E-value: 7.17e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  30 QGEFTSIMGPSGSGKSTLMNII-GCLDkPTTGTYELAGQNI--SNMtETelaRVRnkeIGFVFQNFMLLPRLTALQNVEL 106
Cdd:NF033858 291 RGEIFGFLGSNGCGKSTTMKMLtGLLP-ASEGEAWLFGQPVdaGDI-AT---RRR---VGYMSQAFSLYGELTVRQNLEL 362
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 107 pliYA---GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDtktsTQIMDL 183
Cdd:NF033858 363 ---HArlfHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD----PVARDM 435
                        170       180
                 ....*....|....*....|.
gi 446531759 184 FYEL-----NKQGSTIIMITH 199
Cdd:NF033858 436 FWRLlielsREDGVTIFISTH 456
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
113-221 2.57e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 58.98  E-value: 2.57e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 113 VDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGS 192
Cdd:NF000106 116 LSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGA 195
                         90       100       110
                 ....*....|....*....|....*....|
gi 446531759 193 TIIMITHDREIGEAAARQIVIRD-GNIVQD 221
Cdd:NF000106 196 TVLLTTQYMEEAEQLAHELTVIDrGRVIAD 225
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
17-169 7.59e-09

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 55.13  E-value: 7.59e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  17 SVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmtetelARVRNK---EIGFVFQ--- 90
Cdd:NF033858  13 KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMAD------ARHRRAvcpRIAYMPQglg 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  91 -NfmLLPRLTALQNVELpliYA---GVDKKERRERsLAALTK-VGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:NF033858  87 kN--LYPTLSVFENLDF---FGrlfGQDAAERRRR-IDELLRaTGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLIL 160

                 ....
gi 446531759 166 DEPT 169
Cdd:NF033858 161 DEPT 164
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
30-217 1.76e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 48.91  E-value: 1.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    30 QGEFTSIMGPSGSGKSTLMN-IIGCLDKPTTGTYELAGQNISNMTETELARVRNKEIGfvfqnfmllprltalqnvelpl 108
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARaLARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKK---------------------- 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   109 iyagvdkkerrerslaaltkvgladrathlpNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMD------ 182
Cdd:smart00382  59 -------------------------------ASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLleelrl 107
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 446531759   183 LFYELNKQGSTIIMITH------DREIGEAAARQIVIRDGN 217
Cdd:smart00382 108 LLLLKSEKNLTVILTTNdekdlgPALLRRRFDRRIVLLLIL 148
GguA NF040905
sugar ABC transporter ATP-binding protein;
142-197 9.49e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 36.69  E-value: 9.49e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 142 LSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMI 197
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVI 460
 
Name Accession Description Interval E-value
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-221 9.87e-135

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 377.46  E-value: 9.87e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG1136    4 LLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG1136   84 RRRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:COG1136  164 KLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPELAARADRVIRLRDGRIVSD 225
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
2-218 1.38e-124

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 351.41  E-value: 1.38e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVR 81
Cdd:cd03255    1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03255   81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIVIRDGNI 218
Cdd:cd03255  161 IILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDPELAEYADRIIELRDGKI 218
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
1-221 1.11e-101

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 293.96  E-value: 1.11e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG4181    8 IIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARARL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVdkKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG4181   88 RARHVGFVFQSFQLLPTLTALENVMLPLELAGR--RDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEP 165
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:COG4181  166 AILFADEPTGNLDAATGEQIIDLLFELNReRGTTLVLVTHDPALAARCDRVLRLRAGRLVED 227
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
1-224 1.59e-98

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 285.41  E-value: 1.59e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAEsvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG2884    1 MIRFENVSKRYPGGRE---ALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYL 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG2884   78 RRR-IGVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRP 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAA-ARQIVIRDGNIVQDWRG 224
Cdd:COG2884  157 ELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMpKRVLELEDGRLVRDEAR 221
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
1-221 4.01e-90

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 277.76  E-value: 4.01e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:PRK10535   4 LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:PRK10535  84 RREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGG 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:PRK10535 164 QVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRN 224
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
1-223 2.63e-83

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 248.47  E-value: 2.63e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmtetelarv 80
Cdd:COG1116    7 ALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTG--------- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG1116   78 PGPDRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDP 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDreIGEAA--ARQIVI---RDGNIVQDWR 223
Cdd:COG1116  158 EVLLMDEPFGALDALTRERLQDELLRLwQETGKTVLFVTHD--VDEAVflADRVVVlsaRPGRIVEEID 224
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1-219 3.99e-82

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 248.07  E-value: 3.99e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG1135    1 MIELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RnKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG1135   81 R-RKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNP 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD----REIGEAAArqiVIRDGNIV 219
Cdd:COG1135  160 KVLLCDEATSALDPETTRSILDLLKDINRElGLTIVLITHEmdvvRRICDRVA---VLENGRIV 220
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
2-223 9.77e-79

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 235.44  E-value: 9.77e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmtetelarvR 81
Cdd:cd03293    1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTG---------P 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03293   72 GPDRGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPD 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDreIGEAA--ARQIVI---RDGNIVQDWR 223
Cdd:cd03293  152 VLLLDEPFSALDALTREQLQEELLDIwRETGKTVLLVTHD--IDEAVflADRVVVlsaRPGRIVAEVE 217
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
1-219 3.11e-78

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 234.40  E-value: 3.11e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELaRV 80
Cdd:cd03258    1 MIELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKEL-RK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:cd03258   80 ARRRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNP 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDRE-IGEAAARQIVIRDGNIV 219
Cdd:cd03258  160 KVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEvVKRICDRVAVMEKGEVV 220
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
1-216 6.53e-76

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 227.90  E-value: 6.53e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    1 MINLKGITKSFQNGaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:TIGR02673   1 MIEFHNVSKAYPGG---VAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLPLL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   81 RNKeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:TIGR02673  78 RRR-IGVVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSP 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759  161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEA-AARQIVIRDG 216
Cdd:TIGR02673 157 PLLLADEPTGNLDPDLSERILDLLKRLNKRGTTVIVATHDLSLVDRvAHRVIILDDG 213
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
1-221 3.02e-75

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 227.18  E-value: 3.02e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsNMTETELARV 80
Cdd:COG1126    1 MIEIENLHKSF----GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDL-TDSKKDINKL 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RnKEIGFVFQNFMLLPRLTALQNVELPLIYA-GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNN 159
Cdd:COG1126   76 R-RKVGMVFQQFNLFPHLTVLENVTLAPIKVkKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAME 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 160 PKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHdrEIG---EAAARQIVIRDGNIVQD 221
Cdd:COG1126  155 PKVMLFDEPTSALDPELVGEVLDVMRDLAKEGMTMVVVTH--EMGfarEVADRVVFMDGGRIVEE 217
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
1-221 9.71e-74

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 223.78  E-value: 9.71e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG3638    2 MLELRNLSKRYPGG---TPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRRL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RnKEIGFVFQNFMLLPRLTALQNV------ELPLIYA--GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAV 152
Cdd:COG3638   79 R-RRIGMIFQQFNLVPRLSVLTNVlagrlgRTSTWRSllGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAI 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 153 ARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHDREIGEA-AARQIVIRDGNIVQD 221
Cdd:COG3638  158 ARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAReDGITVVVNLHQVDLARRyADRIIGLRDGRVVFD 228
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
2-218 7.12e-72

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 217.66  E-value: 7.12e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVR 81
Cdd:cd03292    1 IEFINVTKTYPNG---TAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLR 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03292   78 RK-IGVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPT 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAA-RQIVIRDGNI 218
Cdd:cd03292  157 ILIADEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRhRVIALERGKL 214
heterocyst_DevA TIGR02982
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ...
2-219 1.51e-71

ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.


Pssm-ID: 274374 [Multi-domain]  Cd Length: 220  Bit Score: 217.19  E-value: 1.51e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    2 INLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVR 81
Cdd:TIGR02982   2 ISIRNLNHYYGHGSLRKQVLFDINLEINPGEIVILTGPSGSGKTTLLTLIGGLRSVQEGSLKVLGQELHGASKKQLVQLR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   82 nKEIGFVFQNFMLLPRLTALQNVELPL-IYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:TIGR02982  82 -RRIGYIFQAHNLLGFLTARQNVQMALeLQPNLSYQEARERARAMLEAVGLGDHLNYYPHNLSGGQKQRVAIARALVHHP 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  161 KFILADEPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHDREIGEAAARQIVIRDGNIV 219
Cdd:TIGR02982 161 KLVLADEPTAALDSKSGRDVVELMQKLAKeQGCTILMVTHDNRILDVADRILQMEDGKLL 220
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
1-219 3.44e-71

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 216.77  E-value: 3.44e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG1127    5 MIEVRNLTKSF----GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYEL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RnKEIGFVFQNFMLLPRLTALQNVELPLI-YAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNN 159
Cdd:COG1127   81 R-RRIGMLFQGGALFDSLTVFENVAFPLReHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALD 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 160 PKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:COG1127  160 PEILLYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDlDSAFAIADRVAVLADGKII 221
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
7-221 2.37e-70

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 214.68  E-value: 2.37e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   7 ITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNKEIG 86
Cdd:PRK11629  11 LCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLG 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  87 FVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILAD 166
Cdd:PRK11629  91 FIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLAD 170
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 167 EPTGALDTKTSTQIMDLFYELN-KQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:PRK11629 171 EPTGNLDARNADSIFQLLGELNrLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAE 226
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
4-213 1.05e-69

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 212.09  E-value: 1.05e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    4 LKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNK 83
Cdd:TIGR03608   1 LKNISKKFGD----KVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRRE 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   84 EIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFI 163
Cdd:TIGR03608  77 KLGYLFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLI 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 446531759  164 LADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVI 213
Cdd:TIGR03608 157 LADEPTGSLDPKNRDEVLDLLLELNDEGKTIIIVTHDPEVAKQADRVIEL 206
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
1-219 1.94e-69

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 211.98  E-value: 1.94e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTEtELARV 80
Cdd:cd03257    1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSR-RLRKI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFM--LLPRLTALQNVELPLIYAGVDKKE--RRERSLAALTKVGL-ADRATHLPNELSGGQKQRVAVARA 155
Cdd:cd03257   80 RRKEIQMVFQDPMssLNPRMTIGEQIAEPLRIHGKLSKKeaRKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAIARA 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 156 IVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD----REIgeaAARQIVIRDGNIV 219
Cdd:cd03257  160 LALNPKLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDlgvvAKI---ADRVAVMYAGKIV 225
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
1-220 9.08e-69

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 214.58  E-value: 9.08e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTetelARV 80
Cdd:COG3842    5 ALELENVSKRYG----DVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLP----PEK 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNkeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG3842   77 RN--VGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEP 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREigEAAA---RQIVIRDGNIVQ 220
Cdd:COG3842  155 RVLLLDEPLSALDAKLREEMREELRRLQRElGITFIYVTHDQE--EALAladRIAVMNDGRIEQ 216
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
2-218 1.25e-68

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 209.31  E-value: 1.25e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmTETELARVR 81
Cdd:cd03262    1 IEIKNLHKSFGD----FHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTD-DKKNINELR 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQNFMLLPRLTALQNVELPLIYA-GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:cd03262   76 -QKVGMVFQQFNLFPHLTVLENITLAPIKVkGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNP 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHdrEIG---EAAARQIVIRDGNI 218
Cdd:cd03262  155 KVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTH--EMGfarEVADRVIFMDDGRI 213
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
1-219 1.78e-68

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 218.23  E-value: 1.78e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSF-QNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELAR 79
Cdd:COG1123  260 LLEVRNLSKRYpVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRE 339
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRnKEIGFVFQN--FMLLPRLTALQNVELPL-IYAGVDKKERRERSLAALTKVGL-ADRATHLPNELSGGQKQRVAVARA 155
Cdd:COG1123  340 LR-RRVQMVFQDpySSLNPRMTVGDIIAEPLrLHGLLSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIARA 418
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 156 IVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD----REIgeaAARQIVIRDGNIV 219
Cdd:COG1123  419 LALEPKLLILDEPTSALDVSVQAQILNLLRDLQRElGLTYLFISHDlavvRYI---ADRVAVMYDGRIV 484
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
4-220 6.58e-67

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 205.06  E-value: 6.58e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTetelarVRNK 83
Cdd:cd03259    3 LKGLSKTYG----SVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVP------PERR 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFI 163
Cdd:cd03259   73 NIGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLL 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 164 LADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDREigEAAA---RQIVIRDGNIVQ 220
Cdd:cd03259  153 LLDEPLSALDAKLREELREELKELqRELGITTIYVTHDQE--EALAladRIAVMNEGRIVQ 211
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
7-218 1.76e-66

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 204.63  E-value: 1.76e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   7 ITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNKEIG 86
Cdd:PRK10584  12 LKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLRAKHVG 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  87 FVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILAD 166
Cdd:PRK10584  92 FVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFAD 171
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446531759 167 EPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHDREIGEAAARQIVIRDGNI 218
Cdd:PRK10584 172 EPTGNLDRQTGDKIADLLFSLNReHGTTLILVTHDLQLAARCDRRLRLVNGQL 224
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
1-219 7.48e-66

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 206.58  E-value: 7.48e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:PRK11153   1 MIELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:PRK11153  81 RRQ-IGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNP 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDRE-IGEAAARQIVIRDGNIV 219
Cdd:PRK11153 160 KVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDvVKRICDRVAVIDAGRLV 220
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
2-221 9.11e-66

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 202.56  E-value: 9.11e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvr 81
Cdd:COG1122    1 IELENLSFSYPGG---TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRR-- 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nkEIGFVFQN-----FMLlprlTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAI 156
Cdd:COG1122   76 --KVGLVFQNpddqlFAP----TVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVL 149
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIVQD 221
Cdd:COG1122  150 AMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDlDLVAELADRVIVLDDGRIVAD 215
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
2-220 1.54e-65

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 203.64  E-value: 1.54e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVQILHGI------------------DVTL--NQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGT 61
Cdd:cd03294    1 IKIKGLYKIFGKNPQKAFKLLAKgkskeeilkktgqtvgvnDVSLdvREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  62 YELAGQNISNMTETELARVRNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNE 141
Cdd:cd03294   81 VLIDGQDIAAMSRKELRELRRKKISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 142 LSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELN-KQGSTIIMITHDREigEA---AARQIVIRDGN 217
Cdd:cd03294  161 LSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQaELQKTIVFITHDLD--EAlrlGDRIAIMKDGR 238

                 ...
gi 446531759 218 IVQ 220
Cdd:cd03294  239 LVQ 241
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
2-221 2.05e-65

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 202.41  E-value: 2.05e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVR 81
Cdd:cd03256    1 IEVENLSKTYPNG---KKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLR 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQNFMLLPRLTALQNV------ELPLIYA--GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVA 153
Cdd:cd03256   78 -RQIGMIFQQFNLIERLSVLENVlsgrlgRRSTWRSlfGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIA 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIV-IRDGNIVQD 221
Cdd:cd03256  157 RALMQQPKLILADEPVASLDPASSRQVMDLLKRINREeGITVIVSLHQVDLAREYADRIVgLKDGRIVFD 226
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
4-216 1.91e-64

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 198.85  E-value: 1.91e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGAEsvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnk 83
Cdd:cd03225    2 LKNLSFSYPDGAR--PALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRR---- 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQN-----FMLlprlTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVN 158
Cdd:cd03225   76 KVGLVFQNpddqfFGP----TVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAM 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 159 NPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDRE-IGEAAARQIVIRDG 216
Cdd:cd03225  152 DPDILLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDlLLELADRVIVLEDG 210
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
1-221 6.06e-64

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 198.39  E-value: 6.06e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElaRV 80
Cdd:PRK09493   1 MIEFKNVSKHFG----PTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDE--RL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVEL-PLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNN 159
Cdd:PRK09493  75 IRQEAGMVFQQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVK 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 160 PKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHdrEIGEA---AARQIVIRDGNIVQD 221
Cdd:PRK09493 155 PKLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTH--EIGFAekvASRLIFIDKGRIAED 217
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
1-200 3.60e-63

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 199.12  E-value: 3.60e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCLDKP--TTGTYELAGQNISNMTETEL 77
Cdd:COG0444    1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARaILGLLPPPgiTSGEILFDGEDLLKLSEKEL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  78 ARVRNKEIGFVFQNFM--LLPRLTALQNVELPL-IYAGVDKKERRERSLAALTKVGLADRATHL---PNELSGGQKQRVA 151
Cdd:COG0444   81 RKIRGREIQMIFQDPMtsLNPVMTVGDQIAEPLrIHGGLSKAEARERAIELLERVGLPDPERRLdryPHELSGGMRQRVM 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 446531759 152 VARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD 200
Cdd:COG0444  161 IARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRElGLAILFITHD 210
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
2-219 7.39e-63

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 195.41  E-value: 7.39e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVR 81
Cdd:cd03261    1 IELRGLTKSF----GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRLR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKER-RERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:cd03261   77 -RRMGMLFQSGALFDSLTVFENVAFPLREHTRLSEEEiREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDP 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:cd03261  156 ELLLYDEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDlDTAFAIADRIAVLYDGKIV 216
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
1-221 7.98e-63

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 195.59  E-value: 7.98e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    1 MINLKGITKSFQNGaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:TIGR02315   1 MLEVENLSKVYPNG---KQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLRKL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   81 RNKeIGFVFQNFMLLPRLTALQNVELPLIYA--------GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAV 152
Cdd:TIGR02315  78 RRR-IGMIFQHYNLIERLTVLENVLHGRLGYkptwrsllGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAI 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759  153 ARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIV-IRDGNIVQD 221
Cdd:TIGR02315 157 ARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEdGITVIINLHQVDLAKKYADRIVgLKAGEIVFD 227
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
2-221 3.92e-61

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 191.05  E-value: 3.92e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmteTELARVR 81
Cdd:COG1131    1 IEVRGLTKRYGD----KTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVA----RDPAEVR 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:COG1131   73 -RRIGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPE 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIVQD 221
Cdd:COG1131  152 LLILDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYlEEAERLCDRVAIIDKGRIVAD 212
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
1-220 1.30e-60

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 193.37  E-value: 1.30e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTetelARV 80
Cdd:COG3839    3 SLELENVSKSYGG----VEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLP----PKD 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNkeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG3839   75 RN--IAMVFQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREP 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 161 KFILADEPTGALDTK----TSTQIMDLFYELnkqGSTIIMITHDREigEA---AARQIVIRDGNIVQ 220
Cdd:COG3839  153 KVFLLDEPLSNLDAKlrveMRAEIKRLHRRL---GTTTIYVTHDQV--EAmtlADRIAVMNDGRIQQ 214
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
1-219 5.97e-60

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 188.47  E-value: 5.97e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMteteLARV 80
Cdd:COG1124    1 MLEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRR----RRKA 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFM--LLPRLTALQNVELPLIYAGVDkkERRERSLAALTKVGL----ADRathLPNELSGGQKQRVAVAR 154
Cdd:COG1124   77 FRRRVQMVFQDPYasLHPRHTVDRILAEPLRIHGLP--DREERIAELLEQVGLppsfLDR---YPHQLSGGQRQRVAIAR 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 155 AIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDRE-IGEAAARQIVIRDGNIV 219
Cdd:COG1124  152 ALILEPELLLLDEPTSALDVSVQAEILNLLKDLREErGLTYLFVSHDLAvVAHLCDRVAVMQNGRIV 218
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
2-220 6.33e-59

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 185.52  E-value: 6.33e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElarvr 81
Cdd:cd03300    1 IELENVSKFY----GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHK----- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03300   72 -RPVNTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPK 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREigEAAA---RQIVIRDGNIVQ 220
Cdd:cd03300  151 VLLLDEPLGALDLKLRKDMQLELKRLQKElGITFVFVTHDQE--EALTmsdRIAVMNKGKIQQ 211
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-220 1.65e-58

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 185.45  E-value: 1.65e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmtetelarv 80
Cdd:COG4525    3 MLTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG--------- 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG4525   74 PGADRGVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADP 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDREigEA---AARQIVI--RDGNIVQ 220
Cdd:COG4525  154 RFLLMDEPFGALDALTREQMQELLLDVwQRTGKGVFLITHSVE--EAlflATRLVVMspGPGRIVE 217
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
1-221 7.87e-57

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 187.80  E-value: 7.87e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAesVQILHGIDVTLNQGEFTSIMGPSGSGKSTL-MNIIGCLDKP--TTGTYELAGQNISNMTEtel 77
Cdd:COG1123    4 LLEVRDLSVRYPGGD--VPAVDGVSLTIAPGETVALVGESGSGKSTLaLALMGLLPHGgrISGEVLLDGRDLLELSE--- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  78 aRVRNKEIGFVFQNFML-LPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAI 156
Cdd:COG1123   79 -ALRGRRIGMVFQDPMTqLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMAL 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD-REIGEAAARQIVIRDGNIVQD 221
Cdd:COG1123  158 ALDPDLLIADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHDlGVVAEIADRVVVMDDGRIVED 224
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
2-220 1.81e-55

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 179.96  E-value: 1.81e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNI-SNMTetelarV 80
Cdd:COG1118    3 IEVRNISKRF----GSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLfTNLP------P 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG1118   73 RERRVGFVFQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEP 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDREigEA---AARQIVIRDGNIVQ 220
Cdd:COG1118  153 EVLLLDEPFGALDAKVRKELRRWLRRLhDELGGTTVFVTHDQE--EAlelADRVVVMNQGRIEQ 214
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
1-224 6.14e-55

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 175.06  E-value: 6.14e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQilhGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:PRK10908   1 MIRFEHVSKAYLGGRQALQ---GVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFL 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RnKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:PRK10908  78 R-RQIGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKP 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDRE-IGEAAARQIVIRDGNIVQDWRG 224
Cdd:PRK10908 157 AVLLADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGlISRRSYRMLTLSDGHLHGGVGG 221
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-221 2.09e-53

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 175.52  E-value: 2.09e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTetelARVR 81
Cdd:PRK09452  15 VELRGISKSF----DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVP----AENR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NkeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:PRK09452  87 H--VNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPK 164
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREigEAAA---RQIVIRDGNIVQD 221
Cdd:PRK09452 165 VLLLDESLSALDYKLRKQMQNELKALQRKlGITFVFVTHDQE--EALTmsdRIVVMRDGRIEQD 226
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
2-216 2.76e-53

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 169.29  E-value: 2.76e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnMTETELARVR 81
Cdd:cd03229    1 LELKNVSKRYGQ----KTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDL--TDLEDELPPL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVFQNFMLLPRLTALQNVELPliyagvdkkerrerslaaltkvgladrathlpneLSGGQKQRVAVARAIVNNPK 161
Cdd:cd03229   75 RRRIGMVFQDFALFPHLTVLENIALG----------------------------------LSGGQQQRVALARALAMDPD 120
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD-REIGEAAARQIVIRDG 216
Cdd:cd03229  121 VLLLDEPTSALDPITRREVRALLKSLQAQlGITVVLVTHDlDEAARLADRVVVLRDG 177
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
2-220 6.13e-53

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 170.58  E-value: 6.13e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQ--NISNMTETELAR 79
Cdd:COG4161    3 IQLKNINCFYG----SHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHqfDFSQKPSEKAIR 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRNKEIGFVFQNFMLLPRLTALQN-VELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVN 158
Cdd:COG4161   79 LLRQKVGMVFQQYNLWPHLTVMENlIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMM 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 159 NPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIV-IRDGNIVQ 220
Cdd:COG4161  159 EPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFARKVASQVVyMEKGRIIE 221
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
2-220 1.34e-52

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 169.40  E-value: 1.34e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVQilhGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvr 81
Cdd:cd03295    1 IEFENVTKRYGGGKKAVN---NLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRR-- 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nkEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGL-----ADRathLPNELSGGQKQRVAVARAI 156
Cdd:cd03295   76 --KIGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLdpaefADR---YPHELSGGQQQRVGVARAL 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDreIGEA---AARQIVIRDGNIVQ 220
Cdd:cd03295  151 AADPPLLLMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHD--IDEAfrlADRIAIMKNGEIVQ 216
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
1-219 1.71e-51

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 167.14  E-value: 1.71e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG1120    1 MLEAENLSVGYGG----RPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 rnkeIGFVFQNFMLLPRLTALQNVEL---PLIYA-GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAI 156
Cdd:COG1120   77 ----IAYVPQEPPAPFGLTVRELVALgryPHLGLfGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARAL 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHDreIGEAAA---RQIVIRDGNIV 219
Cdd:COG1120  153 AQEPPLLLLDEPTSHLDLAHQLEVLELLRRLAReRGRTVVMVLHD--LNLAARyadRLVLLKDGRIV 217
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
1-200 2.62e-51

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 166.42  E-value: 2.62e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmtetelARV 80
Cdd:COG1121    6 AIELENLTVSYGG----RPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPP--------RRA 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKeIGFVFQNFML---LPrLTALQNVELPLIYA----GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVA 153
Cdd:COG1121   74 RRR-IGYVPQRAEVdwdFP-ITVRDVVLMGRYGRrglfRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLA 151
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD 200
Cdd:COG1121  152 RALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHD 198
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
2-220 2.96e-51

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 166.34  E-value: 2.96e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqnGAEsvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQ--NISNMTETELAR 79
Cdd:PRK11124   3 IQLNGINCFY--GAH--QALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNhfDFSKTPSDKAIR 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRNKEIGFVFQNFMLLPRLTALQN-VELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVN 158
Cdd:PRK11124  79 ELRRNVGMVFQQYNLWPHLTVQQNlIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMM 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 159 NPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIV-IRDGNIVQ 220
Cdd:PRK11124 159 EPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVyMENGHIVE 221
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
4-218 4.01e-51

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 164.60  E-value: 4.01e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELarvRnK 83
Cdd:COG4619    3 LEGLSFRVGGK----PILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEW---R-R 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPrltalQNVE--LPLIYAGVDKKERRERSLAALTKVGLADRATHLP-NELSGGQKQRVAVARAIVNNP 160
Cdd:COG4619   75 QVAYVPQEPALWG-----GTVRdnLPFPFQLRERKFDRERALELLERLGLPPDILDKPvERLSGGERQRLALIRALLLQP 149
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDRE-IGEAAARQIVIRDGNI 218
Cdd:COG4619  150 DVLLLDEPTSALDPENTRRVEELLREYLAEeGRAVLWVSHDPEqIERVADRVLTLEAGRL 209
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
1-200 9.56e-51

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 165.36  E-value: 9.56e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnMTET----- 75
Cdd:COG4598    8 ALEVRDLHKSF----GDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIR-LKPDrdgel 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  76 ------ELARVRNKeIGFVFQNFMLLPRLTALQNV-ELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQ 148
Cdd:COG4598   83 vpadrrQLQRIRTR-LGMVFQSFNLWSHMTVLENViEAPVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQ 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446531759 149 RVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD 200
Cdd:COG4598  162 RAAIARALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEEGRTMLVVTHE 213
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
1-220 1.40e-50

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 164.54  E-value: 1.40e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYEL------AGQNISNmtE 74
Cdd:PRK11264   3 AIEVKNLVKKFHGQ----TVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditidTARSLSQ--Q 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  75 TELARVRNKEIGFVFQNFMLLPRLTALQNV-ELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVA 153
Cdd:PRK11264  77 KGLIRQLRQHVGFVFQNFNLFPHRTVLENIiEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIA 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIG-EAAARQIVIRDGNIVQ 220
Cdd:PRK11264 157 RALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFArDVADRAIFMDQGRIVE 224
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
2-221 4.96e-49

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 161.47  E-value: 4.96e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    2 INLKGITKSFQ-NGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:TIGR04521   1 IKLKNVSYIYQpGTPFEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKDL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   81 RnKEIGFVFQN-----FmllpRLTALQNVELPLIYAGVDKKERRERSLAALTKVGL----ADRAthlPNELSGGQKQRVA 151
Cdd:TIGR04521  81 R-KKVGLVFQFpehqlF----EETVYKDIAFGPKNLGLSEEEAEERVKEALELVGLdeeyLERS---PFELSGGQMRRVA 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759  152 VARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDRE-IGEAAARQIVIRDGNIVQD 221
Cdd:TIGR04521 153 IAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEkGLTVILVTHSMEdVAEYADRVIVMHKGKIVLD 224
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
10-219 6.22e-49

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 167.55  E-value: 6.22e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  10 SFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKS-TLMNIIGCLDKP---TTGTYELAGQNISNMTETELARVRNKEI 85
Cdd:COG4172   15 AFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvTALSILRLLPDPaahPSGSILFDGQDLLGLSERELRRIRGNRI 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  86 GFVFQNFMllprlTAL--------QNVELPLIYAGVDKKERRERSLAALTKVGLADRATHL---PNELSGGQKQRVAVAR 154
Cdd:COG4172   95 AMIFQEPM-----TSLnplhtigkQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRLdayPHQLSGGQRQRVMIAM 169
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 155 AIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD----REIgeaAARQIVIRDGNIV 219
Cdd:COG4172  170 ALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRElGMALLLITHDlgvvRRF---ADRVAVMRQGEIV 236
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
4-218 1.90e-48

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 159.46  E-value: 1.90e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYeLAGQnisnmteTELARVRNk 83
Cdd:PRK11247  15 LNAVSKRYGER----TVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGEL-LAGT-------APLAEARE- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPRLTALQNVELPLiyagvdKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFI 163
Cdd:PRK11247  82 DTRLMFQDARLLPWKKVIDNVGLGL------KGQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLL 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 164 LADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDreIGEAAA---RQIVIRDGNI 218
Cdd:PRK11247 156 LLDEPLGALDALTRIEMQDLIESLwQQHGFTVLLVTHD--VSEAVAmadRVLLIEEGKI 212
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
2-220 2.17e-48

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 158.66  E-value: 2.17e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTetelarVR 81
Cdd:cd03296    3 IEVRNVSKRF----GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVP------VQ 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVFQNFMLLPRLTALQNVELPL----IYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIV 157
Cdd:cd03296   73 ERNVGFVFQHYALFRHMTVFDNVAFGLrvkpRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALA 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDREIG-EAAARQIVIRDGNIVQ 220
Cdd:cd03296  153 VEPKVLLLDEPFGALDAKVRKELRRWLRRLhDELHVTTVFVTHDQEEAlEVADRVVVMNKGRIEQ 217
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
20-212 4.25e-48

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 156.92  E-value: 4.25e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMtetelarvrNKEIGFVFQNFMLLP--R 97
Cdd:cd03235   14 VLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKE---------RKRIGYVPQRRSIDRdfP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTALQNVELPLIYAGV----DKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:cd03235   85 ISVRDVVLMGLYGHKGlfrrLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVD 164
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 446531759 174 TKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIV 212
Cdd:cd03235  165 PKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVL 203
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
2-218 6.22e-48

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 155.25  E-value: 6.22e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmteTELARVR 81
Cdd:cd03230    1 IEVRNLSKRYGKK----TALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIK----KEPEEVK 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQNFMLLPRLTALQNVelpliyagvdkkerrerslaaltkvgladrathlpnELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03230   73 -RRIGYLPEEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPE 115
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNI 218
Cdd:cd03230  116 LLILDEPTSGLDPESRREFWELLRELKKEGKTILLSSHIlEEAERLCDRVAILNNGRI 173
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
1-216 7.32e-48

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 156.83  E-value: 7.32e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSF----QNGAEsVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGT--YELAGQ--NISNM 72
Cdd:COG4778    4 LLEVENLSKTFtlhlQGGKR-LPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSilVRHDGGwvDLAQA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  73 TETELARVRNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHL-PNELSGGQKQRVA 151
Cdd:COG4778   83 SPREILALRRRTIGYVSQFLRVIPRVSALDVVAEPLLERGVDREEARARARELLARLNLPERLWDLpPATFSGGEQQRVN 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 152 VARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAA-RQIVIRDG 216
Cdd:COG4778  163 IARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEEVREAVAdRVVDVTPF 228
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
11-200 3.82e-47

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 157.97  E-value: 3.82e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  11 FQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRnKEIGFVFQ 90
Cdd:COG4608   24 FGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGRELRPLR-RRMQMVFQ 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  91 N-FMLL-PRLTALQNVELPLIYAGV-DKKERRERSLAALTKVGLadRATHL---PNELSGGQKQRVAVARAIVNNPKFIL 164
Cdd:COG4608  103 DpYASLnPRMTVGDIIAEPLRIHGLaSKAERRERVAELLELVGL--RPEHAdryPHEFSGGQRQRIGIARALALNPKLIV 180
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 446531759 165 ADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD 200
Cdd:COG4608  181 CDEPVSALDVSIQAQVLNLLEDLQDElGLTYLFISHD 217
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
36-221 4.86e-47

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 157.66  E-value: 4.86e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   36 IMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTEtelarvRNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDK 115
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPP------HLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPR 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  116 KERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTI 194
Cdd:TIGR01187  75 AEIKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQlGITF 154
                         170       180
                  ....*....|....*....|....*...
gi 446531759  195 IMITHDREIGEAAARQIVI-RDGNIVQD 221
Cdd:TIGR01187 155 VFVTHDQEEAMTMSDRIAImRKGKIAQI 182
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
11-219 6.03e-46

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 159.46  E-value: 6.03e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  11 FQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTL-MNIIGCLdkPTTGTYELAGQNISNMTETELARVRnKEIGFVF 89
Cdd:COG4172  292 FRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALLRLI--PSEGEIRFDGQDLDGLSRRALRPLR-RRMQVVF 368
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  90 QNFM--LLPRLTALQNVELPLI--YAGVDKKERRERSLAALTKVGLADRATH-LPNELSGGQKQRVAVARAIVNNPKFIL 164
Cdd:COG4172  369 QDPFgsLSPRMTVGQIIAEGLRvhGPGLSAAERRARVAEALEEVGLDPAARHrYPHEFSGGQRQRIAIARALILEPKLLV 448
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 165 ADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD----REIgeaAARQIVIRDGNIV 219
Cdd:COG4172  449 LDEPTSALDVSVQAQILDLLRDLQREhGLAYLFISHDlavvRAL---AHRVMVMKDGKVV 505
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
2-200 6.25e-46

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 151.95  E-value: 6.25e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCL-----DKPTTGTYELAGQNISNMTETE 76
Cdd:cd03260    1 IELRDLNVYY----GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLDGKDIYDLDVDV 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  77 LArVRnKEIGFVFQNFMLLPrLTALQNVELPLIYAGV-DKKERRERSLAALTKVGL----ADRATHLpnELSGGQKQRVA 151
Cdd:cd03260   77 LE-LR-RRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIkLKEELDERVEEALRKAALwdevKDRLHAL--GLSGGQQQRLC 151
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446531759 152 VARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQgSTIIMITHD 200
Cdd:cd03260  152 LARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHN 199
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
1-221 1.10e-45

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 151.45  E-value: 1.10e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNgaesvQILHgIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmTETELARv 80
Cdd:COG3840    1 MLRLDDLTYRYGD-----FPLR-FDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDL---TALPPAE- 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 rnKEIGFVFQNFMLLPRLTALQNVELpliyaGVDKK-----ERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARA 155
Cdd:COG3840   71 --RPVSMLFQENNLFPHLTVAQNIGL-----GLRPGlkltaEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARC 143
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 156 IVNNPKFILADEPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHD-REIGEAAARQIVIRDGNIVQD 221
Cdd:COG3840  144 LVRKRPILLLDEPFSALDPALRQEMLDLVDELCReRGLTVLMVTHDpEDAARIADRVLLVADGRIAAD 211
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
4-200 1.22e-45

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 151.44  E-value: 1.22e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFqnGaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnK 83
Cdd:cd03219    3 VRGLTKRF--G--GLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIAR---L 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPRLTALQNVEL--------PLIYAGVDKKER--RERSLAALTKVGLADRATHLPNELSGGQKQRVAVA 153
Cdd:cd03219   76 GIGRTFQIPRLFPELTVLENVMVaaqartgsGLLLARARREEReaRERAEELLERVGLADLADRPAGELSYGQQRRLEIA 155
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD 200
Cdd:cd03219  156 RALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHD 202
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
2-220 3.65e-45

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 153.70  E-value: 3.65e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMtetelaRVR 81
Cdd:PRK10851   3 IEIANIKKSFGR----TQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRL------HAR 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVFQNFMLLPRLTALQNVELpliyaGVDKKERRERSLAALTK---------VGLADRATHLPNELSGGQKQRVAV 152
Cdd:PRK10851  73 DRKVGFVFQHYALFRHMTVFDNIAF-----GLTVLPRRERPNAAAIKakvtqllemVQLAHLADRYPAQLSGGQKQRVAL 147
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 153 ARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGS-TIIMITHDREIG-EAAARQIVIRDGNIVQ 220
Cdd:PRK10851 148 ARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKfTSVFVTHDQEEAmEVADRVVVMSQGNIEQ 217
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
19-221 4.52e-45

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 148.35  E-value: 4.52e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnkEIGFVFQnfmllprl 98
Cdd:cd03214   13 TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELAR----KIAYVPQ-------- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  99 talqnvelpliyagvdkkerrerslaALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTST 178
Cdd:cd03214   81 --------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQI 134
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 446531759 179 QIMDLFYELNKQ-GSTIIMITHDreIGEAAA---RQIVIRDGNIVQD 221
Cdd:cd03214  135 ELLELLRRLARErGKTVVMVLHD--LNLAARyadRVILLKDGRIVAQ 179
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
2-220 4.89e-45

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 149.33  E-value: 4.89e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElarvR 81
Cdd:cd03301    1 VELENVTKRF----GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKD----R 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NkeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKE--RRERSLAALTKVG-LADRathLPNELSGGQKQRVAVARAIVN 158
Cdd:cd03301   73 D--IAMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEidERVREVAELLQIEhLLDR---KPKQLSGGQRQRVALGRAIVR 147
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 159 NPKFILADEPTGALDTKTSTQIMDlfyELNK----QGSTIIMITHDREIGEAAARQI-VIRDGNIVQ 220
Cdd:cd03301  148 EPKVFLMDEPLSNLDAKLRVQMRA---ELKRlqqrLGTTTIYVTHDQVEAMTMADRIaVMNDGQIQQ 211
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
20-215 6.75e-45

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 148.78  E-value: 6.75e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCLDKP--TTGTYELAGQNIsnmteTELArVRNKEIGFVFQNFMLLP 96
Cdd:COG4136   16 LLAPLSLTVAPGEILTLMGPSGSGKSTLLAaIAGTLSPAfsASGEVLLNGRRL-----TALP-AEQRRIGILFQDDLLFP 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 RLTALQNV--ELPliyAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDT 174
Cdd:COG4136   90 HLSVGENLafALP---PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDA 166
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 446531759 175 KTSTQIMDL-FYELNKQGSTIIMITHDREIGEAAARQIVIRD 215
Cdd:COG4136  167 ALRAQFREFvFEQIRQRGIPALLVTHDEEDAPAAGRVLDLGN 208
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
2-216 7.72e-45

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 147.53  E-value: 7.72e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGItkSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVr 81
Cdd:cd03228    1 IEFKNV--SFSYPGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKN- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nkeIGFVFQNFMLLPRlTALQNVelpliyagvdkkerrerslaaltkvgladrathlpneLSGGQKQRVAVARAIVNNPK 161
Cdd:cd03228   78 ---IAYVPQDPFLFSG-TIRENI-------------------------------------LSGGQRQRIAIARALLRDPP 116
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITHDREIGEAAARQIVIRDG 216
Cdd:cd03228  117 ILILDEATSALDPETEALILEALRAL-AKGKTVIVIAHRLSTIRDADRIIVLDDG 170
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
1-202 1.92e-44

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 149.08  E-value: 1.92e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAesvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmtetelarv 80
Cdd:PRK11248   1 MLQISHLYADYGGKP----ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEG--------- 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:PRK11248  68 PGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANP 147
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDRE 202
Cdd:PRK11248 148 QLLLLDEPFGALDAFTREQMQTLLLKLwQETGKQVLLITHDIE 190
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
21-169 1.99e-44

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 145.48  E-value: 1.99e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTEtelaRVRNKEIGFVFQNFMLLPRLTA 100
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDER----KSLRKEIGYVFQDPQLFPRLTV 76
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759  101 LQNVELPLIYAGVDKKERRERSLAALTKVGLAD----RATHLPNELSGGQKQRVAVARAIVNNPKFILADEPT 169
Cdd:pfam00005  77 RENLRLGLLLKGLSKREKDARAEEALEKLGLGDladrPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
1-219 2.03e-44

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 148.47  E-value: 2.03e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmteTELARV 80
Cdd:COG4555    1 MIEVENLSKKYG----KVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDV-----RKEPRE 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELpliYA---GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIV 157
Cdd:COG4555   72 ARRQIGVLPDERGLYDRLTVRENIRY---FAelyGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALV 148
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:COG4555  149 HDPKVLLLDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHImQEVEALCDRVVILHKGKVV 211
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1-224 4.53e-44

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 148.31  E-value: 4.53e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNG-AESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElar 79
Cdd:COG1101    1 MLELKNLSKTFNPGtVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYK--- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 vRNKEIGFVFQNFML--LPRLTALQNveLPLIYA---------GVDKKERRE-RSLAALTKVGLADRATHLPNELSGGQK 147
Cdd:COG1101   78 -RAKYIGRVFQDPMMgtAPSMTIEEN--LALAYRrgkrrglrrGLTKKRRELfRELLATLGLGLENRLDTKVGLLSGGQR 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 148 QRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDREigEAAA---RQIVIRDGNIVQDWR 223
Cdd:COG1101  155 QALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIvEENNLTTLMVTHNME--QALDygnRLIMMHEGRIILDVS 232

                 .
gi 446531759 224 G 224
Cdd:COG1101  233 G 233
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
4-216 5.39e-44

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 144.69  E-value: 5.39e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnk 83
Cdd:cd00267    2 IENLSFRYGGR----TALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRR---- 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQnfmllprltalqnvelpliyagvdkkerrerslaaltkvgladrathlpneLSGGQKQRVAVARAIVNNPKFI 163
Cdd:cd00267   74 RIGYVPQ---------------------------------------------------LSGGQRQRVALARALLLNPDLL 102
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446531759 164 LADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDG 216
Cdd:cd00267  103 LLDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDpELAELAADRVIVLKDG 156
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
1-200 7.42e-44

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 147.49  E-value: 7.42e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFqnGAesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELAR- 79
Cdd:COG0411    4 LLEVRGLTKRF--GG--LVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIARl 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 --VRnkeigfVFQNFMLLPRLTALQNVE---------------LPLIYAGVDKKERRERSLAALTKVGLADRATHLPNEL 142
Cdd:COG0411   80 giAR------TFQNPRLFPELTVLENVLvaaharlgrgllaalLRLPRARREEREARERAEELLERVGLADRADEPAGNL 153
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 143 SGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHD 200
Cdd:COG0411  154 SYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDeRGITILLIEHD 212
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
2-221 1.65e-43

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 146.81  E-value: 1.65e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    2 INLKGITKSFQNgaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmtETELARVR 81
Cdd:TIGR04520   1 IEVENVSFSYPE--SEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLD--EENLWEIR 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   82 NKeIGFVFQN---------------FmllprltALQNvelpliyAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQ 146
Cdd:TIGR04520  77 KK-VGMVFQNpdnqfvgatveddvaF-------GLEN-------LGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQ 141
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759  147 KQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHDREigEA--AARQIVIRDGNIVQD 221
Cdd:TIGR04520 142 KQRVAIAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKeEGITVISITHDME--EAvlADRVIVMNKGKIVAE 217
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
2-221 9.51e-43

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 146.00  E-value: 9.51e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESV-QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELA-- 78
Cdd:PRK13651   3 IKVKNIVKIFNKKLPTElKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKTKEKek 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  79 -------------RVRN-----KEIGFVFQ--NFMLLPrltalQNVELPLIYA----GVDKKERRERSLAALTKVGLA-- 132
Cdd:PRK13651  83 vleklviqktrfkKIKKikeirRRVGVVFQfaEYQLFE-----QTIEKDIIFGpvsmGVSKEEAKKRAAKYIELVGLDes 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 133 --DRAthlPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDRE-IGEAAAR 209
Cdd:PRK13651 158 ylQRS---PFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDnVLEWTKR 234
                        250
                 ....*....|..
gi 446531759 210 QIVIRDGNIVQD 221
Cdd:PRK13651 235 TIFFKDGKIIKD 246
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
1-215 9.96e-43

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 143.00  E-value: 9.96e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETelarv 80
Cdd:COG4133    2 MLEAENLSCRRGE----RLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDARED----- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELpliYAGVDKKER-RERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNN 159
Cdd:COG4133   73 YRRRLAYLGHADGLKPELTVRENLRF---WAALYGLRAdREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSP 149
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 160 PKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDrEIGEAAARQIVIRD 215
Cdd:COG4133  150 APLWLLDEPFTALDAAGVALLAELIAAHLARGGAVLLTTHQ-PLELAAARVLDLGD 204
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
21-206 1.72e-42

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 143.38  E-value: 1.72e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmTETELARVrnkeigFVFQNFMLLPRLTA 100
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQI---TEPGPDRM------VVFQNYSLLPWLTV 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  101 LQNVELPL--IYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTST 178
Cdd:TIGR01184  72 RENIALAVdrVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRG 151
                         170       180
                  ....*....|....*....|....*....
gi 446531759  179 QIMDLFYEL-NKQGSTIIMITHDreIGEA 206
Cdd:TIGR01184 152 NLQEELMQIwEEHRVTVLMVTHD--VDEA 178
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-220 1.71e-41

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 144.22  E-value: 1.71e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTEtelarv 80
Cdd:PRK11650   3 GLKLQAVRKSYDGK---TQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEP------ 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLA---DRAthlPNELSGGQKQRVAVARAIV 157
Cdd:PRK11650  74 ADRDIAMVFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEpllDRK---PRELSGGQRQRVAMGRAIV 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 158 NNPKFILADEPTGALDTKTSTQ----IMDLFYELnkqGSTIIMITHDREigEA---AARQIVIRDGNIVQ 220
Cdd:PRK11650 151 REPAVFLFDEPLSNLDAKLRVQmrleIQRLHRRL---KTTSLYVTHDQV--EAmtlADRVVVMNGGVAEQ 215
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
19-212 2.03e-41

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 141.26  E-value: 2.03e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETE------------LARVRnkeIG 86
Cdd:PRK10619  19 EVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDgqlkvadknqlrLLRTR---LT 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  87 FVFQNFMLLPRLTALQNV-ELPLIYAGVDKKERRERSLAALTKVGLADRAT-HLPNELSGGQKQRVAVARAIVNNPKFIL 164
Cdd:PRK10619  96 MVFQHFNLWSHMTVLENVmEAPIQVLGLSKQEARERAVKYLAKVGIDERAQgKYPVHLSGGQQQRVSIARALAMEPEVLL 175
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446531759 165 ADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIV 212
Cdd:PRK10619 176 FDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVI 223
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
2-221 3.39e-41

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 148.44  E-value: 3.39e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGItkSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMtetELARVR 81
Cdd:COG2274  474 IELENV--SFRYPGDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQI---DPASLR 548
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKeIGFVFQNFMLLPRlTALQNVelpliyAGVDKKERRERSLAALTKVGLADRATHLPN-----------ELSGGQKQRV 150
Cdd:COG2274  549 RQ-IGVVLQDVFLFSG-TIRENI------TLGDPDATDEEIIEAARLAGLHDFIEALPMgydtvvgeggsNLSGGQRQRL 620
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 151 AVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:COG2274  621 AIARALLRNPRILILDEATSALDAETEAIILENLRRL-LKGRTVIIIAHRLSTIRLADRIIVLDKGRIVED 690
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
2-221 6.48e-41

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 138.48  E-value: 6.48e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGaesvQILHGIDVTLNQGeFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvr 81
Cdd:cd03264    1 LQLENLTKRYGKK----RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRR-- 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nkeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03264   74 ---IGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPS 150
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKqGSTIIMITHDREIGEAAARQI-VIRDGNIVQD 221
Cdd:cd03264  151 ILIVDEPTAGLDPEERIRFRNLLSELGE-DRIVILSTHIVEDVESLCNQVaVLNKGKLVFE 210
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
21-220 7.06e-41

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 139.39  E-value: 7.06e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTEtelarvRNKEIGFVFQNFMLLPRLTA 100
Cdd:cd03299   15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPP------EKRDISYVPQNYALFPHMTV 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 101 LQNVELPLIYAGVDKKERRERSLAALTKVGLadraTHL----PNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:cd03299   89 YKNIAYGLKKRKVDKKEIERKVLEIAEMLGI----DHLlnrkPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRT 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446531759 177 STQIMDLFYELNKQ-GSTIIMITHDREigEAAA---RQIVIRDGNIVQ 220
Cdd:cd03299  165 KEKLREELKKIRKEfGVTVLHVTHDFE--EAWAladKVAIMLNGKLIQ 210
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
25-221 1.62e-40

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 137.62  E-value: 1.62e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  25 DVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNisnMTETELARvrnKEIGFVFQNFMLLPRLTALQNV 104
Cdd:cd03298   18 DLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVD---VTAAPPAD---RPVSMLFQENNLFAHLTVEQNV 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 105 ELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLF 184
Cdd:cd03298   92 GLGLSPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLV 171
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 446531759 185 YELNKQ-GSTIIMITHDREIGEA-AARQIVIRDGNIVQD 221
Cdd:cd03298  172 LDLHAEtKMTVLMVTHQPEDAKRlAQRVVFLDNGRIAAQ 210
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
4-222 4.00e-40

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 143.24  E-value: 4.00e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFqnGAesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElarVRNK 83
Cdd:COG1129    7 MRGISKSF--GG--VKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRD---AQAA 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPRLTALQNV---ELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:COG1129   80 GIAIIHQELNLVPNLSVAENIflgREPRRGGLIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDA 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIVQDW 222
Cdd:COG1129  160 RVLILDEPTASLTEREVERLFRIIRRLKAQGVAIIYISHRlDEVFEIADRVTVLRDGRLVGTG 222
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
1-219 9.58e-40

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 137.52  E-value: 9.58e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESvqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnMTETELARV 80
Cdd:PRK13639   1 ILETRDLKYSYPDGTEA---LKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIK-YDKKSLLEV 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RnKEIGFVFQN---FMLLPrlTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIV 157
Cdd:PRK13639  77 R-KTVGIVFQNpddQLFAP--TVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILA 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQI-VIRDGNIV 219
Cdd:PRK13639 154 MKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVyVMSDGKII 216
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
2-220 9.93e-40

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 143.37  E-value: 9.93e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVr 81
Cdd:COG4987  334 LELEDVSFRYPGAGRPV--LDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRR- 410
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nkeIGFVFQNfmllPRL---TALQNveLPLIYAGVDkkerRERSLAALTKVGLADRATHLPN-----------ELSGGQK 147
Cdd:COG4987  411 ---IAVVPQR----PHLfdtTLREN--LRLARPDAT----DEELWAALERVGLGDWLAALPDgldtwlgeggrRLSGGER 477
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 148 QRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNkQGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:COG4987  478 RRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEAL-AGRTVLLITHRLAGLERMDRILVLEDGRIVE 549
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
15-220 1.07e-39

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 142.97  E-value: 1.07e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  15 AESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnkEIGFVFQNfml 94
Cdd:COG4988  347 PGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRR----QIAWVPQN--- 419
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  95 lPRL---TALQNVELPLIYAGvdkkerRERSLAALTKVGLADRATHLPN-------E----LSGGQKQRVAVARAIVNNP 160
Cdd:COG4988  420 -PYLfagTIRENLRLGRPDAS------DEELEAALEAAGLDEFVAALPDgldtplgEggrgLSGGQAQRLALARALLRDA 492
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:COG4988  493 PLLLLDEPTAHLDAETEAEILQALRRL-AKGRTVILITHRLALLAQADRILVLDDGRIVE 551
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
26-220 2.00e-39

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 139.78  E-value: 2.00e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  26 VTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNKEIGFVFQNFMLLPRLTALQNVE 105
Cdd:PRK10070  49 LAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMPHMTVLDNTA 128
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 106 LPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFY 185
Cdd:PRK10070 129 FGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELV 208
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 446531759 186 ELN-KQGSTIIMITHD-REIGEAAARQIVIRDGNIVQ 220
Cdd:PRK10070 209 KLQaKHQRTIVFISHDlDEAMRIGDRIAIMQNGEVVQ 245
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
18-219 2.41e-39

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 134.87  E-value: 2.41e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  18 VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnKEIGFVFQNFMLLPR 97
Cdd:cd03224   13 SQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERAR---AGIGYVPEGRRIFPE 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTALQNVELPL-IYAGVDKKERRERSLAALTKvgLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:cd03224   90 LTVEENLLLGAyARRRAKRKARLERVYELFPR--LKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKI 167
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 446531759 177 STQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:cd03224  168 VEEIFEAIRELRDEGVTILLVEQNaRFALEIADRAYVLERGRVV 211
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
24-222 4.89e-39

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 133.96  E-value: 4.89e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  24 IDVTLNqGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNKEIGFVFQNFMLLPRLTALQN 103
Cdd:cd03297   17 IDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKINLPPQQRKIGLVFQQYALFPHLNVREN 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 104 VELPLIYAGVDKKERRERSLAALTKVG-LADRATHlpnELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMD 182
Cdd:cd03297   96 LAFGLKRKRNREDRISVDELLDLLGLDhLLNRYPA---QLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLP 172
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 446531759 183 LFYELNKQ-GSTIIMITHD-REIGEAAARQIVIRDGNIVQDW 222
Cdd:cd03297  173 ELKQIKKNlNIPVIFVTHDlSEAEYLADRIVVMEDGRLQYIG 214
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
18-200 5.25e-39

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 137.02  E-value: 5.25e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  18 VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRnKEIGFVFQN--FMLL 95
Cdd:PRK11308  28 VKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPEAQKLLR-QKIQIVFQNpyGSLN 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  96 PRLTALQNVELPL-IYAGVDKKERRERSLAALTKVGL----ADRATHLpneLSGGQKQRVAVARAIVNNPKFILADEPTG 170
Cdd:PRK11308 107 PRKKVGQILEEPLlINTSLSAAERREKALAMMAKVGLrpehYDRYPHM---FSGGQRQRIAIARALMLDPDVVVADEPVS 183
                        170       180       190
                 ....*....|....*....|....*....|.
gi 446531759 171 ALDTKTSTQIMDLFYELNKQ-GSTIIMITHD 200
Cdd:PRK11308 184 ALDVSVQAQVLNLMMDLQQElGLSYVFISHD 214
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
1-221 8.70e-39

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 134.76  E-value: 8.70e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCL---DKPTTGTYELAGQNISNmtETEL 77
Cdd:PRK09984   4 IIRVEKLAKTFNQH----QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgDKSAGSHIELLGRTVQR--EGRL 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  78 ARVRNK---EIGFVFQNFMLLPRLTALQNVEL------PLIYAGVD--KKERRERSLAALTKVGLADRATHLPNELSGGQ 146
Cdd:PRK09984  78 ARDIRKsraNTGYIFQQFNLVNRLSVLENVLIgalgstPFWRTCFSwfTREQKQRALQALTRVGMVHFAHQRVSTLSGGQ 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 147 KQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIV-IRDGNIVQD 221
Cdd:PRK09984 158 QQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRYCERIVaLRQGHVFYD 234
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
1-200 1.12e-38

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 136.39  E-value: 1.12e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKS-TLMNIIGCLDKP--TTGTYELAGQNISNMTETEL 77
Cdd:PRK09473  12 LLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSqTAFALMGLLAANgrIGGSATFNGREILNLPEKEL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  78 ARVRNKEIGFVFQNFMllprlTAL--------QNVELPLIYAGVDKKERRERSLAALTKVGLAD---RATHLPNELSGGQ 146
Cdd:PRK09473  92 NKLRAEQISMIFQDPM-----TSLnpymrvgeQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEarkRMKMYPHEFSGGM 166
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 147 KQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGST-IIMITHD 200
Cdd:PRK09473 167 RQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHD 221
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
5-219 1.46e-38

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 134.19  E-value: 1.46e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   5 KGITKSFQN-----GAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTetelAR 79
Cdd:COG4167    8 RNLSKTFKYrtglfRRQQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLEYGD----YK 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRNKEIGFVFQ--NFMLLPRLTALQNVELPLIYA-GVDKKERRERSLAALTKVGL-ADRATHLPNELSGGQKQRVAVARA 155
Cdd:COG4167   84 YRCKHIRMIFQdpNTSLNPRLNIGQILEEPLRLNtDLTAEEREERIFATLRLVGLlPEHANFYPHMLSSGQKQRVALARA 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 156 IVNNPKFILADEPTGALDTKTSTQIMDLFYELN-KQGSTIIMITHDREIGEAAARQ-IVIRDGNIV 219
Cdd:COG4167  164 LILQPKIIIADEALAALDMSVRSQIINLMLELQeKLGISYIYVSQHLGIVKHISDKvLVMHQGEVV 229
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
24-220 2.76e-38

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 135.25  E-value: 2.76e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  24 IDVTLNQGEFTSIMGPSGSGKS-TLMNIIGCLDKP---TTGTYELAGQNISNMTETELARVRNKEIGFVFQNFM--LLPR 97
Cdd:PRK11022  26 ISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYPgrvMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMtsLNPC 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LT-ALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHL---PNELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:PRK11022 106 YTvGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRLdvyPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALD 185
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446531759 174 TKTSTQIMDLFYELNKQGS-TIIMITHDRE-IGEAAARQIVIRDGNIVQ 220
Cdd:PRK11022 186 VTIQAQIIELLLELQQKENmALVLITHDLAlVAEAAHKIIVMYAGQVVE 234
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
4-220 3.51e-38

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 135.23  E-value: 3.51e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGAesvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTetelarVRNK 83
Cdd:PRK11432   9 LKNITKRFGSNT----VIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRS------IQQR 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFI 163
Cdd:PRK11432  79 DICMVFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVL 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 164 LADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREigEAAARQ---IVIRDGNIVQ 220
Cdd:PRK11432 159 LFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQS--EAFAVSdtvIVMNKGKIMQ 217
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
1-220 3.52e-38

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 136.12  E-value: 3.52e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFqNGAESVQilhGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElarv 80
Cdd:PRK11607  19 LLEIRNLTKSF-DGQHAVD---DVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQ---- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 rnKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:PRK11607  91 --RPINMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRP 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 161 KFILADEPTGALDTK----TSTQIMDLfyeLNKQGSTIIMITHDREIGEAAARQIVIRD-GNIVQ 220
Cdd:PRK11607 169 KLLLLDEPMGALDKKlrdrMQLEVVDI---LERVGVTCVMVTHDQEEAMTMAGRIAIMNrGKFVQ 230
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
4-219 6.43e-38

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 131.09  E-value: 6.43e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmteTELARVRnK 83
Cdd:cd03263    3 IRNLTKTYKKG--TKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIR----TDRKAAR-Q 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPRLTALQNVElplIYA---GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:cd03263   76 SLGYCPQFDALFDELTVREHLR---FYArlkGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGP 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITHDREIGEAAARQIVI-RDGNIV 219
Cdd:cd03263  153 SVLLLDEPTSGLDPASRRAIWDLILEV-RKGRSIILTTHSMDEAEALCDRIAImSDGKLR 211
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
4-219 2.91e-37

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 128.91  E-value: 2.91e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGAEsvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmtetelARVRNK 83
Cdd:cd03226    2 IENISFSYKKGTE---ILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIK-------AKERRK 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQN-----FMllprltalQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVN 158
Cdd:cd03226   72 SIGYVMQDvdyqlFT--------DSVREELLLGLKELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLS 143
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 159 NPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDRE-IGEAAARQIVIRDGNIV 219
Cdd:cd03226  144 GKDLLIFDEPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEfLAKVCDRVLLLANGAIV 205
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
1-219 3.49e-37

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 130.24  E-value: 3.49e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGItkSFQNGaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNII-GCLdKPTTGTYELAGQNISNMTETELAR 79
Cdd:COG4559    1 MLEAENL--SVRLG--GRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLtGEL-TPSSGEVRLNGRPLAAWSPWELAR 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VR-----NKEIGFVFqnfmllprlTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVAR 154
Cdd:COG4559   76 RRavlpqHSSLAFPF---------TVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLAR 146
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 155 AIV-------NNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDreIGEAAA---RQIVIRDGNIV 219
Cdd:COG4559  147 VLAqlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHD--LNLAAQyadRILLLHQGRLV 219
cbiO PRK13641
energy-coupling factor transporter ATPase;
21-220 5.56e-37

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 130.72  E-value: 5.56e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETE-LARVRnKEIGFVFQnF--MLLPR 97
Cdd:PRK13641  23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKnLKKLR-KKVSLVFQ-FpeAQLFE 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTALQNVELPLIYAGVDKKERRERSLAALTKVGLA-DRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:PRK13641 101 NTVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSeDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEG 180
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446531759 177 STQIMDLFYELNKQGSTIIMITHDR-EIGEAAARQIVIRDGNIVQ 220
Cdd:PRK13641 181 RKEMMQLFKDYQKAGHTVILVTHNMdDVAEYADDVLVLEHGKLIK 225
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
19-199 7.64e-37

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 129.39  E-value: 7.64e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTL------MN--IIGCLdkpTTGTYELAGQNISNmTETELARVRnKEIGFVFQ 90
Cdd:COG1117   25 QALKDINLDIPENKVTALIGPSGCGKSTLlrclnrMNdlIPGAR---VEGEILLDGEDIYD-PDVDVVELR-RRVGMVFQ 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  91 NFMLLPrLTALQNVELPLIYAGV-DKKERRERSLAALTKVGL----ADRATHLPNELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:COG1117  100 KPNPFP-KSIYDNVAYGLRLHGIkSKSELDEIVEESLRKAALwdevKDRLKKSALGLSGGQQQRLCIARALAVEPEVLLM 178
                        170       180       190
                 ....*....|....*....|....*....|....
gi 446531759 166 DEPTGALDTKTSTQIMDLFYELnKQGSTIIMITH 199
Cdd:COG1117  179 DEPTSALDPISTAKIEELILEL-KKDYTIVIVTH 211
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
2-219 1.14e-36

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 127.87  E-value: 1.14e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqNGAESVQilhGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmtetELARVR 81
Cdd:cd03265    1 IEVENLVKKY-GDFEAVR---GVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVR----EPREVR 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03265   73 -RRIGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPE 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHDREIGEAAARQIVIRD-GNIV 219
Cdd:cd03265  152 VLFLDEPTIGLDPQTRAHVWEYIEKLKEeFGMTILLTTHYMEEAEQLCDRVAIIDhGRII 211
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
2-220 1.23e-36

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 131.69  E-value: 1.23e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNisnMTETELArvr 81
Cdd:PRK11000   4 VTLRNVTKAYGD----VVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKR---MNDVPPA--- 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:PRK11000  74 ERGVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPS 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIVIRD-GNIVQ 220
Cdd:PRK11000 154 VFLLDEPLSNLDAALRVQMRIEISRLHKRlGRTMIYVTHDQVEAMTLADKIVVLDaGRVAQ 214
cbiO TIGR01166
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...
11-200 1.26e-36

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130234 [Multi-domain]  Cd Length: 190  Bit Score: 127.15  E-value: 1.26e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   11 FQNGAEsvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsNMTETELARVRnKEIGFVFQ 90
Cdd:TIGR01166   1 YPGGPE---VLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPL-DYSRKGLLERR-QRVGLVFQ 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   91 N---FMLLPRLTalQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADE 167
Cdd:TIGR01166  76 DpddQLFAADVD--QDVAFGPLNLGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDE 153
                         170       180       190
                  ....*....|....*....|....*....|...
gi 446531759  168 PTGALDTKTSTQIMDLFYELNKQGSTIIMITHD 200
Cdd:TIGR01166 154 PTAGLDPAGREQMLAILRRLRAEGMTVVISTHD 186
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
1-219 1.45e-36

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 127.87  E-value: 1.45e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmteTELARV 80
Cdd:cd03266    1 MITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVV----KEPAEA 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKeIGFVFQNFMLLPRLTALQNVELpliYAGVDKKERRErSLAALTKVG-------LADRAThlpNELSGGQKQRVAVA 153
Cdd:cd03266   77 RRR-LGFVSDSTGLYDRLTARENLEY---FAGLYGLKGDE-LTARLEELAdrlgmeeLLDRRV---GGFSTGMRQKVAIA 148
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:cd03266  149 RALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHImQEVERLCDRVVVLHRGRVV 215
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
1-221 2.21e-36

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 128.65  E-value: 2.21e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGA-----ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMtET 75
Cdd:PRK10419   3 LLNVSGLSHHYAHGGlsgkhQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKL-NR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  76 ELARVRNKEIGFVFQNFM--LLPRLTALQNVELPLIY-AGVDKKERRERSLAALTKVGLADR-ATHLPNELSGGQKQRVA 151
Cdd:PRK10419  82 AQRKAFRRDIQMVFQDSIsaVNPRKTVREIIREPLRHlLSLDKAERLARASEMLRAVDLDDSvLDKRPPQLSGGQLQRVC 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 152 VARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGST-IIMITHD-REIGEAAARQIVIRDGNIVQD 221
Cdd:PRK10419 162 LARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTaCLFITHDlRLVERFCQRVMVMDNGQIVET 233
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
16-220 2.81e-36

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 133.75  E-value: 2.81e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  16 ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELarvRNKeIGFVFQNFMLL 95
Cdd:COG1132  351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESL---RRQ-IGVVPQDTFLF 426
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  96 PRlTALQNVELPLIYAGvdkkerRERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVNNPKFIL 164
Cdd:COG1132  427 SG-TIRENIRYGRPDAT------DEEVEEAAKAAQAHEFIEALPDgydtvvgergvNLSGGQRQRIAIARALLKDPPILI 499
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 165 ADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITH--------DReIgeaaarqIVIRDGNIVQ 220
Cdd:COG1132  500 LDEATSALDTETEALIQEALERL-MKGRTTIVIAHrlstirnaDR-I-------LVLDDGRIVE 554
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
2-219 9.41e-36

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 127.44  E-value: 9.41e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGItkSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmtETELARVR 81
Cdd:PRK13635   6 IRVEHI--SFRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLS---EETVWDVR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQN----FMllpRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIV 157
Cdd:PRK13635  81 -RQVGMVFQNpdnqFV---GATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLA 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKQGS-TIIMITHDREIGEAAARQIVIRDGNIV 219
Cdd:PRK13635 157 LQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGiTVLSITHDLDEAAQADRVIVMNKGEIL 219
cbiO PRK13646
energy-coupling factor transporter ATPase;
2-220 1.21e-35

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 127.20  E-value: 1.21e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAE-SVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:PRK13646   3 IRFDNVSYTYQKGTPyEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRP 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQnfmlLPRLTALQ-NVELPLIYA----GVDKKERRERSLAALTKVGLA-DRATHLPNELSGGQKQRVAVAR 154
Cdd:PRK13646  83 VRKRIGMVFQ----FPESQLFEdTVEREIIFGpknfKMNLDEVKNYAHRLLMDLGFSrDVMSQSPFQMSGGQMRKIAIVS 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 155 AIVNNPKFILADEPTGALDTKTSTQIMDLFYELN-KQGSTIIMITHD-REIGEAAARQIVIRDGNIVQ 220
Cdd:PRK13646 159 ILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQtDENKTIILVSHDmNEVARYADEVIVMKEGSIVS 226
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
1-221 3.47e-35

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 125.97  E-value: 3.47e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTL--NQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmtETELA 78
Cdd:PRK13633   4 MIKCKNVSYKYESNEESTEKLALDDVNLevKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSD--EENLW 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  79 RVRNKEiGFVFQNfmllP--RLTAlQNVELPLIYA----GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAV 152
Cdd:PRK13633  82 DIRNKA-GMVFQN----PdnQIVA-TIVEEDVAFGpenlGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAI 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 153 ARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:PRK13633 156 AGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKyGITIILITHYMEEAVEADRIIVMDSGKVVME 225
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
1-219 2.33e-34

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 122.88  E-value: 2.33e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:COG4604    1 MIEIKNVSKRYGG----KVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 rnkeIGFVFQNFMLLPRLTALQNVEL---PliYAG----VDKKERRERSLAALTKVGLADRatHLpNELSGGQKQRVAVA 153
Cdd:COG4604   77 ----LAILRQENHINSRLTVRELVAFgrfP--YSKgrltAEDREIIDEAIAYLDLEDLADR--YL-DELSGGQRQRAFIA 147
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDreIGEAA--ARQIV-IRDGNIV 219
Cdd:COG4604  148 MVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLaDELGKTVVIVLHD--INFAScyADHIVaMKDGRVV 215
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
18-219 4.70e-34

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 121.63  E-value: 4.70e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  18 VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGcLDKPTTGTYELAGQNISNMTETELARvrnKEIGFVFQNFMLLP 96
Cdd:COG0410   16 IHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKaISG-LLPPRSGSIRFDGEDITGLPPHRIAR---LGIGYVPEGRRIFP 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 RLTALQNVELPLiYAGVDKKERRERslaaLTKVG-----LADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGA 171
Cdd:COG0410   92 SLTVEENLLLGA-YARRDRAEVRAD----LERVYelfprLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLG 166
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446531759 172 LDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:COG0410  167 LAPLIVEEIFEIIRRLNREGVTILLVEQNaRFALEIADRAYVLERGRIV 215
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
14-213 7.57e-34

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 119.65  E-value: 7.57e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  14 GAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTyelagqnisnmteteLARVRNKEIGFVFQNFM 93
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGT---------------VRRAGGARVAYVPQRSE 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  94 L---LPrLTALQNVEL----PLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILAD 166
Cdd:NF040873  66 VpdsLP-LTVRDLVAMgrwaRRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLD 144
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 446531759 167 EPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVI 213
Cdd:NF040873 145 EPTTGLDAESRERIIALLAEEHARGATVVVVTHDLELVRRADPCVLL 191
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
21-220 8.15e-34

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 122.44  E-value: 8.15e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMT-ETELARVRnKEIGFVFQnF--MLLPR 97
Cdd:PRK13634  23 LYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKkNKKLKPLR-KKVGIVFQ-FpeHQLFE 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTALQNVELPLIYAGVDKKERRERSLAALTKVGL-ADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:PRK13634 101 ETVEKDICFGPMNFGVSEEDAKQKAREMIELVGLpEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKG 180
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446531759 177 STQIMDLFYELNK-QGSTIIMITHDREIGEAAARQ-IVIRDGNIVQ 220
Cdd:PRK13634 181 RKEMMEMFYKLHKeKGLTTVLVTHSMEDAARYADQiVVMHKGTVFL 226
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
1-219 9.88e-34

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 121.64  E-value: 9.88e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGItkSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELarv 80
Cdd:PRK13632   7 MIKVENV--SFSYPNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEI--- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKeIGFVFQN----FMllpRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAI 156
Cdd:PRK13632  82 RKK-IGIIFQNpdnqFI---GATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVL 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGS-TIIMITHDREIGEAAARQIVIRDGNIV 219
Cdd:PRK13632 158 ALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKkTLISITHDMDEAILADKVIVFSEGKLI 221
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
25-220 1.04e-33

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 120.35  E-value: 1.04e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   25 DVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElarvrnKEIGFVFQNFMLLPRLTALQNV 104
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQ------RPVSMLFQENNLFAHLTVRQNI 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  105 ELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLF 184
Cdd:TIGR01277  92 GLGLHPGLKLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALV 171
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 446531759  185 YEL-NKQGSTIIMITHDREIGEAAARQI-VIRDGNIVQ 220
Cdd:TIGR01277 172 KQLcSERQRTLLMVTHHLSDARAIASQIaVVSQGKIKV 209
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
2-218 1.22e-33

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 118.86  E-value: 1.22e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGItkSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvr 81
Cdd:cd03246    1 LEVENV--SFRYPGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGD-- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nkEIGFVFQNFMLLPrltalqnvelpliyagvdkkerrerslaaltkvG-LADrathlpNELSGGQKQRVAVARAIVNNP 160
Cdd:cd03246   77 --HVGYLPQDDELFS---------------------------------GsIAE------NILSGGQRQRLGLARALYGNP 115
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNI 218
Cdd:cd03246  116 RILVLDEPNSHLDVEGERALNQAIAALKAAGATRIVIAHRPETLASADRILVLEDGRV 173
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
4-219 2.06e-33

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 117.91  E-value: 2.06e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmteTELARVRNK 83
Cdd:cd03216    3 LRGITKRF----GGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSF---ASPRDARRA 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQnfmllprltalqnvelpliyagvdkkerrerslaaltkvgladrathlpneLSGGQKQRVAVARAIVNNPKFI 163
Cdd:cd03216   76 GIAMVYQ---------------------------------------------------LSVGERQMVEIARALARNARLL 104
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 164 LADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:cd03216  105 ILDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRlDEVFEIADRVTVLRDGRVV 161
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
2-224 6.55e-33

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 118.09  E-value: 6.55e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETelarvr 81
Cdd:cd03268    1 LKTNDLTKTYGKK----RVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEA------ 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRErslaALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03268   71 LRRIGALIEAPGFYPNLTARENLRLLARLLGIRKKRIDE----VLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPD 146
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIVqdWRG 224
Cdd:cd03268  147 LLILDEPTNGLDPDGIKELRELILSLRDQGITVLISSHLlSEIQKVADRIGIINKGKLI--EEG 208
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
2-199 7.09e-33

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 119.25  E-value: 7.09e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCL-----DKPTTGTYELAGQNISNMTETE 76
Cdd:PRK14247   4 IEIRDLKVSFGQ----VEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIFKMDVIE 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  77 LARvrnkEIGFVFQNFMLLPRLTALQNVELPLIYAGV--DKKERRERSLAALTKVGL----ADRATHLPNELSGGQKQRV 150
Cdd:PRK14247  80 LRR----RVQMVFQIPNPIPNLSIFENVALGLKLNRLvkSKKELQERVRWALEKAQLwdevKDRLDAPAGKLSGGQQQRL 155
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446531759 151 AVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQgSTIIMITH 199
Cdd:PRK14247 156 CIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD-MTIVLVTH 203
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
19-199 7.69e-33

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 117.27  E-value: 7.69e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKP--TTGTYELAGQNISnmtetelARVRNKEIGFVFQNFMLLP 96
Cdd:cd03213   23 QLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGlgVSGEVLINGRPLD-------KRSFRKIIGYVPQDDILHP 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 RLTALQNvelpLIYAgvdkkerrerslAALTKvgladrathlpneLSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:cd03213   96 TLTVRET----LMFA------------AKLRG-------------LSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSS 146
                        170       180
                 ....*....|....*....|...
gi 446531759 177 STQIMDLFYELNKQGSTIIMITH 199
Cdd:cd03213  147 ALQVMSLLRRLADTGRTIICSIH 169
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
1-219 1.56e-32

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 122.83  E-value: 1.56e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFqnGaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQ--NISNMTEtelA 78
Cdd:COG3845    5 ALELRGITKRF--G--GVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKpvRIRSPRD---A 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  79 rvRNKEIGFVFQNFMLLPRLTALQNVEL---PLIYAGVDKKERRERSLAALTKVGLA---DRATHlpnELSGGQKQRVAV 152
Cdd:COG3845   78 --IALGIGMVHQHFMLVPNLTVAENIVLglePTKGGRLDRKAARARIRELSERYGLDvdpDAKVE---DLSVGEQQRVEI 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 153 ARAIVNNPKFILADEPTGALdtkTSTQIMDLFY---ELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:COG3845  153 LKALYRGARILILDEPTAVL---TPQEADELFEilrRLAAEGKSIIFITHKlREVMAIADRVTVLRRGKVV 220
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
23-200 2.67e-32

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 119.43  E-value: 2.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  23 GIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGcLDKPTTGTYELAGQNISNMTETELARVRnKEIGFVFQNFM--LLPRLT 99
Cdd:PRK15079  39 GVTLRLYEGETLGVVGESGCGKSTFARaIIG-LVKATDGEVAWLGKDLLGMKDDEWRAVR-SDIQMIFQDPLasLNPRMT 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQNVELPLI--YAGVDKKERRERSLAALTKVGLadrathLPN-------ELSGGQKQRVAVARAIVNNPKFILADEPTG 170
Cdd:PRK15079 117 IGEIIAEPLRtyHPKLSRQEVKDRVKAMMLKVGL------LPNlinryphEFSGGQCQRIGIARALILEPKLIICDEPVS 190
                        170       180       190
                 ....*....|....*....|....*....|.
gi 446531759 171 ALDTKTSTQIMDLFYELNKQ-GSTIIMITHD 200
Cdd:PRK15079 191 ALDVSIQAQVVNLLQQLQREmGLSLIFIAHD 221
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
2-220 2.71e-32

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 122.22  E-value: 2.71e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    2 INLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLD--KPTTG--TYELA------------ 65
Cdd:TIGR03269   1 IEVKNLTKKF----DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGriIYHVAlcekcgyverps 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   66 --GQNIS--------------NMTETELARVRnKEIGFVFQ-NFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTK 128
Cdd:TIGR03269  77 kvGEPCPvcggtlepeevdfwNLSDKLRRRIR-KRIAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEM 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  129 VGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDRE-IGEA 206
Cdd:TIGR03269 156 VQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKAsGISMVLTSHWPEvIEDL 235
                         250
                  ....*....|....
gi 446531759  207 AARQIVIRDGNIVQ 220
Cdd:TIGR03269 236 SDKAIWLENGEIKE 249
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
24-219 1.64e-31

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 117.89  E-value: 1.64e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  24 IDVTLNQGEF-------------TSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAG---QNisnmTETELARVRNK-EIG 86
Cdd:COG4148    5 VDFRLRRGGFtldvdftlpgrgvTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGevlQD----SARGIFLPPHRrRIG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  87 FVFQNFMLLPRLTALQNVElpliYAgvDKKERRERSLAALTKV----GLADRATHLPNELSGGQKQRVAVARAIVNNPKF 162
Cdd:COG4148   81 YVFQEARLFPHLSVRGNLL----YG--RKRAPRAERRISFDEVvellGIGHLLDRRPATLSGGERQRVAIGRALLSSPRL 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 163 ILADEPTGALDTKTSTQIMDLFYELNKQGST-IIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:COG4148  155 LLMDEPLAALDLARKAEILPYLERLRDELDIpILYVSHSlDEVARLADHVVLLEQGRVV 213
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
6-218 2.43e-31

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 114.56  E-value: 2.43e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   6 GITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnKEI 85
Cdd:cd03218    5 NLSKRYGKR----KVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRAR---LGI 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  86 GFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:cd03218   78 GYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLL 157
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 166 DEPTGALDTKTSTQIMDLFYELNKQGstI-IMIT-HD-REIGEAAARQIVIRDGNI 218
Cdd:cd03218  158 DEPFAGVDPIAVQDIQKIIKILKDRG--IgVLITdHNvRETLSITDRAYIIYEGKV 211
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
19-221 2.54e-31

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 115.25  E-value: 2.54e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNII-GCLdKPTTGTYELAGQNISNMTETELARVR-----NKEIGFVFqnf 92
Cdd:PRK13548  16 TLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALsGEL-SPDSGEVRLNGRPLADWSPAELARRRavlpqHSSLSFPF--- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  93 mllprlTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIV------NNPKFILAD 166
Cdd:PRK13548  92 ------TVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWLLLD 165
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 167 EPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDreIGEAAA---RQIVIRDGNIVQD 221
Cdd:PRK13548 166 EPTSALDLAHQHHVLRLARQLaHERGLAVIVVLHD--LNLAARyadRIVLLHQGRLVAD 222
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
1-221 2.58e-31

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 114.80  E-value: 2.58e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTG-TYELAGQNisnMTETELAR 79
Cdd:COG1119    3 LLELRNVTVRR----GGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGER---RGGEDVWE 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRnKEIGFV---FQNFmLLPRLTALQNVelpL--------IYAGVDKKERrERSLAALTKVGLADRATHLPNELSGGQKQ 148
Cdd:COG1119   76 LR-KRIGLVspaLQLR-FPRDETVLDVV---LsgffdsigLYREPTDEQR-ERARELLELLGLAHLADRPFGTLSQGEQR 149
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 149 RVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGS-TIIMITHDRE-IGEAAARQIVIRDGNIVQD 221
Cdd:COG1119  150 RVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGApTLVLVTHHVEeIPPGITHVLLLKDGRVVAA 224
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
25-221 2.74e-31

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 114.29  E-value: 2.74e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  25 DVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNisnMTETELARvrnKEIGFVFQNFMLLPRLTALQNV 104
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQD---HTTTPPSR---RPVSMLFQENNLFSHLTVAQNI 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 105 ELPLiYAGVDKKERRERSLAALT-KVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDL 183
Cdd:PRK10771  93 GLGL-NPGLKLNAAQREKLHAIArQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTL 171
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 446531759 184 FYEL-NKQGSTIIMITHDREigEA---AARQIVIRDGNIVQD 221
Cdd:PRK10771 172 VSQVcQERQLTLLMVSHSLE--DAariAPRSLVVADGRIAWD 211
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
2-219 6.03e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 114.45  E-value: 6.03e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESvqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElarVR 81
Cdd:PRK13647   5 IEVEDLHFRYKDGTKA---LKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKW---VR 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKeIGFVFQNfmllP-----RLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAI 156
Cdd:PRK13647  79 SK-VGLVFQD----PddqvfSSTVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVL 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIG-EAAARQIVIRDGNIV 219
Cdd:PRK13647 154 AMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAaEWADQVIVLKEGRVL 217
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
16-220 7.35e-31

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 113.09  E-value: 7.35e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  16 ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELarvRNKeIGFVFQNFMLL 95
Cdd:cd03254   14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSL---RSM-IGVVLQDTFLF 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  96 PRlTALQNVELPLIYAgvdkkeRRERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVNNPKFIL 164
Cdd:cd03254   90 SG-TIMENIRLGRPNA------TDEEVIEAAKEAGAHDFIMKLPNgydtvlgenggNLSQGERQLLAIARAMLRDPKILI 162
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 165 ADEPTGALDTKTSTQIMDLFYELNKqGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:cd03254  163 LDEATSNIDTETEKLIQEALEKLMK-GRTSIIIAHRLSTIKNADKILVLDDGKIIE 217
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
24-218 1.26e-30

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 115.59  E-value: 1.26e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   24 IDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNKEIGFVFQNFMLLPRLTALQN 103
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGIFLPPEKRRIGYVFQEARLFPHLSVRGN 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  104 VELPLIYAGVDKKERRERSLAALTKVG-LADRathLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMD 182
Cdd:TIGR02142  96 LRYGMKRARPSERRISFERVIELLGIGhLLGR---LPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILP 172
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 446531759  183 LFYELNKQ-GSTIIMITHD-REIGEAAARQIVIRDGNI 218
Cdd:TIGR02142 173 YLERLHAEfGIPILYVSHSlQEVLRLADRVVVLEDGRV 210
cbiO PRK13649
energy-coupling factor transporter ATPase;
2-199 1.63e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 113.69  E-value: 1.63e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAE-SVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:PRK13649   3 INLQNVSYTYQAGTPfEGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQnfmlLPRL-----TALQNVELPLIYAGVDKKERRERSLAALTKVGLADRA-THLPNELSGGQKQRVAVAR 154
Cdd:PRK13649  83 IRKKVGLVFQ----FPESqlfeeTVLKDVAFGPQNFGVSQEEAEALAREKLALVGISESLfEKNPFELSGGQMRRVAIAG 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446531759 155 AIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:PRK13649 159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTH 203
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1-219 5.23e-30

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 112.51  E-value: 5.23e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNII-GCLDkPTTGTYELAGQNISnmtetelAR 79
Cdd:COG4152    1 MLELKGLTKRFGD----KTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIIlGILA-PDSGEVLWDGEPLD-------PE 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRNKeIGFvfqnfM-----LLPRLTALQNvelpLIY----AGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRV 150
Cdd:COG4152   69 DRRR-IGY-----LpeergLYPKMKVGEQ----LVYlarlKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKV 138
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 151 AVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIV-IRDGNIV 219
Cdd:COG4152  139 QLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIViINKGRKV 208
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1-200 5.55e-30

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 112.17  E-value: 5.55e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGItkSFQNGAESvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:PRK11831   7 LVDMRGV--SFTRGNRC--IFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RnKEIGFVFQNFMLLPRLTALQNVELPLiyagvdkkerRERS-----------LAALTKVGLADRATHLPNELSGGQKQR 149
Cdd:PRK11831  83 R-KRMSMLFQSGALFTDMNVFDNVAYPL----------REHTqlpapllhstvMMKLEAVGLRGAAKLMPSELSGGMARR 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446531759 150 VAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD 200
Cdd:PRK11831 152 AALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSAlGVTCVVVSHD 203
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
11-220 6.12e-30

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 115.96  E-value: 6.12e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  11 FQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKS-TLMNIIGCLDKP----TTGTYELAGQNISNMTETELARVRNKEI 85
Cdd:PRK15134  15 FRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPpvvyPSGDIRFHGESLLHASEQTLRGVRGNKI 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  86 GFVFQNFMLlpRLTALQNVELPL-----IYAGVDKKERRERSLAALTKVGL---ADRATHLPNELSGGQKQRVAVARAIV 157
Cdd:PRK15134  95 AMIFQEPMV--SLNPLHTLEKQLyevlsLHRGMRREAARGEILNCLDRVGIrqaAKRLTDYPHQLSGGERQRVMIAMALL 172
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREI-GEAAARQIVIRDGNIVQ 220
Cdd:PRK15134 173 TRPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITHNLSIvRKLADRVAVMQNGRCVE 237
cbiO PRK13637
energy-coupling factor transporter ATPase;
21-219 9.12e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 111.68  E-value: 9.12e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmTETELARVRnKEIGFVFQ--NFMLLPRl 98
Cdd:PRK13637  23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITD-KKVKLSDIR-KKVGLVFQypEYQLFEE- 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  99 TALQNVELPLIYAGVDKKERRERSLAALTKVGL-----ADRAthlPNELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:PRK13637 100 TIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLdyedyKDKS---PFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLD 176
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446531759 174 TKTSTQIMDLFYELNKQ-GSTIIMITHDRE-IGEAAARQIVIRDGNIV 219
Cdd:PRK13637 177 PKGRDEILNKIKELHKEyNMTIILVSHSMEdVAKLADRIIVMNKGKCE 224
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
19-199 1.00e-29

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 111.09  E-value: 1.00e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCL-----DKPTTGTYELAGQNISNmTETELARVRnKEIGFVFQNFM 93
Cdd:PRK14267  18 HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNIYS-PDVDPIEVR-REVGMVFQYPN 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  94 LLPRLTALQNVELPLIYAGV--DKKERRERSLAALTKVGL----ADRATHLPNELSGGQKQRVAVARAIVNNPKFILADE 167
Cdd:PRK14267  96 PFPHLTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAALwdevKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDE 175
                        170       180       190
                 ....*....|....*....|....*....|..
gi 446531759 168 PTGALDTKTSTQIMDLFYELnKQGSTIIMITH 199
Cdd:PRK14267 176 PTANIDPVGTAKIEELLFEL-KKEYTIVLVTH 206
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
19-220 1.04e-29

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 110.40  E-value: 1.04e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVrnkeIGFVFQNfMLLPRL 98
Cdd:cd03253   15 PVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRA----IGVVPQD-TVLFND 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  99 TALQNVElpliYAGVDKKErrERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVNNPKFILADE 167
Cdd:cd03253   90 TIGYNIR----YGRPDATD--EEVIEAAKAAQIHDKIMRFPDgydtivgerglKLSGGEKQRVAIARAILKNPPILLLDE 163
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446531759 168 PTGALDTKTSTQIMDLFYELNKqGSTIIMITHD-REIGEaAARQIVIRDGNIVQ 220
Cdd:cd03253  164 ATSALDTHTEREIQAALRDVSK-GRTTIVIAHRlSTIVN-ADKIIVLKDGRIVE 215
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
1-200 1.21e-29

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 112.31  E-value: 1.21e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCLDKPTTGT---YELAGQNISNMTETE 76
Cdd:COG4170    3 LLDIRNLTIEIDTPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKaICGITKDNWHVTadrFRWNGIDLLKLSPRE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  77 LARVRNKEIGFVFQNFM--LLPRLTALQNVE--LPLIYAGVD----KKERRERSLAALTKVGLADratH------LPNEL 142
Cdd:COG4170   83 RRKIIGREIAMIFQEPSscLDPSAKIGDQLIeaIPSWTFKGKwwqrFKWRKKRAIELLHRVGIKD---HkdimnsYPHEL 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 143 SGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNK-QGSTIIMITHD 200
Cdd:COG4170  160 TEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQlQGTSILLISHD 218
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
10-220 1.53e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 111.00  E-value: 1.53e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  10 SFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELarvrNKEIGFVF 89
Cdd:PRK13648  14 SFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKL----RKHIGIVF 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  90 QNfmllPR-----LTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFIL 164
Cdd:PRK13648  90 QN----PDnqfvgSIVKYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVII 165
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 165 ADEPTGALDTKTSTQIMDLFYELNKQGS-TIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:PRK13648 166 LDEATSMLDPDARQNLLDLVRKVKSEHNiTIISITHDLSEAMEADHVIVMNKGTVYK 222
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
19-220 1.77e-29

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 114.80  E-value: 1.77e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKST----LMNIIgcldkPTTGTYELAGQNISNMTETELARVRNKeIGFVFQ--NF 92
Cdd:PRK15134 300 VVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEIWFDGQPLHNLNRRQLLPVRHR-IQVVFQdpNS 373
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  93 MLLPRLTALQNVE--LPLIYAGVDKKERRERSLAALTKVGLADRATH-LPNELSGGQKQRVAVARAIVNNPKFILADEPT 169
Cdd:PRK15134 374 SLNPRLNVLQIIEegLRVHQPTLSAAQREQQVIAVMEEVGLDPETRHrYPAEFSGGQRQRIAIARALILKPSLIILDEPT 453
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446531759 170 GALDTKTSTQIMDLFYEL-NKQGSTIIMITHDREIGEAAARQ-IVIRDGNIVQ 220
Cdd:PRK15134 454 SSLDKTVQAQILALLKSLqQKHQLAYLFISHDLHVVRALCHQvIVLRQGEVVE 506
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
2-221 1.79e-29

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 109.22  E-value: 1.79e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNgaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVr 81
Cdd:cd03245    3 IEFRNVSFSYPN--QEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRN- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nkeIGFVFQNFMLLPRlTALQNVELPLIYAgvdkkeRRERSLAALTKVGLADRATHLPN-----------ELSGGQKQRV 150
Cdd:cd03245   80 ---IGYVPQDVTLFYG-TLRDNITLGAPLA------DDERILRAAELAGVTDFVNKHPNgldlqigergrGLSGGQRQAV 149
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 151 AVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:cd03245  150 ALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQL-LGDKTLIIITHRPSLLDLVDRIIVMDSGRIVAD 219
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
21-199 2.45e-29

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 109.87  E-value: 2.45e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLM---NIIGCLDK--PTTGTYELAGQNI-SNMTETELARvrnKEIGFVFQNFML 94
Cdd:PRK14239  21 LNSVSLDFYPNEITALIGPSGSGKSTLLrsiNRMNDLNPevTITGSIVYNGHNIySPRTDTVDLR---KEIGMVFQQPNP 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  95 LPrLTALQNVELPLIYAGVDKKERR----ERSLAALT-----KVGLADRAThlpnELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:PRK14239  98 FP-MSIYENVVYGLRLKGIKDKQVLdeavEKSLKGASiwdevKDRLHDSAL----GLSGGQQQRVCIARVLATSPKIILL 172
                        170       180       190
                 ....*....|....*....|....*....|....
gi 446531759 166 DEPTGALDTKTSTQIMDLFYELnKQGSTIIMITH 199
Cdd:PRK14239 173 DEPTSALDPISAGKIEETLLGL-KDDYTMLLVTR 205
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
15-206 3.32e-29

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 108.65  E-value: 3.32e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  15 AESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTeTELARvrnKEIGFVFQNFML 94
Cdd:PRK10247  17 AGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLK-PEIYR---QQVSYCAQTPTL 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  95 LPRlTALQNVELPliYAGVDKKERRERSLAALTKVGLADRATHLP-NELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:PRK10247  93 FGD-TVYDNLIFP--WQIRNQQPDPAIFLDDLERFALPDTILTKNiAELSGGEKQRISLIRNLQFMPKVLLLDEITSALD 169
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 446531759 174 TKTSTQIMDLFYELNK-QGSTIIMITHDR-EIGEA 206
Cdd:PRK10247 170 ESNKHNVNEIIHRYVReQNIAVLWVTHDKdEINHA 204
cbiO PRK13650
energy-coupling factor transporter ATPase;
1-218 4.62e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 109.82  E-value: 4.62e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNisnMTETELARV 80
Cdd:PRK13650   4 IIEVKNLTFKYKEDQEKYT-LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDL---LTEENVWDI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKeIGFVFQN----FMllpRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAI 156
Cdd:PRK13650  80 RHK-IGMVFQNpdnqFV---GATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAV 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIVIRDGNI 218
Cdd:PRK13650 156 AMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDyQMTVISITHDLDEVALSDRVLVMKNGQV 218
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
18-220 7.21e-29

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 108.40  E-value: 7.21e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  18 VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMtetELARVRNKeIGFVFQNFMLLPR 97
Cdd:cd03249   16 VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDL---NLRWLRSQ-IGLVSQEPVLFDG 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 lTALQNVELPLIYAGVDKKERrerslaALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVNNPKFILAD 166
Cdd:cd03249   92 -TIAENIRYGKPDATDEEVEE------AAKKANIHDFIMSLPDgydtlvgergsQLSGGQKQRIAIARALLRNPKILLLD 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446531759 167 EPTGALDTKTSTQIMDLFYELnKQGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:cd03249  165 EATSALDAESEKLVQEALDRA-MKGRTTIVIAHRLSTIRNADLIAVLQNGQVVE 217
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
19-199 1.97e-28

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 112.06  E-value: 1.97e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTT---GTYELAGQNIsnmtETELARVRNkeiGFVFQNFMLL 95
Cdd:TIGR00955  39 HLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVkgsGSVLLNGMPI----DAKEMRAIS---AYVQQDDLFI 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   96 PRLTALQNvelpLIY-------AGVDKKERRERSLAALTKVGL---ADRATHLPNE---LSGGQKQRVAVARAIVNNPKF 162
Cdd:TIGR00955 112 PTLTVREH----LMFqahlrmpRRVTKKEKRERVDEVLQALGLrkcANTRIGVPGRvkgLSGGERKRLAFASELLTDPPL 187
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 446531759  163 ILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:TIGR00955 188 LFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIH 224
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
2-213 3.04e-28

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 111.22  E-value: 3.04e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    2 INLKGITKSFQNGAESVQilhGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvr 81
Cdd:TIGR02857 322 LEFSGVSVAYPGRRPALR---PVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRD-- 396
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   82 nkEIGFVFQNFMLLPRlTALQNVELPLIYAGVDKKERrerslaALTKVGLADRATHLP-----------NELSGGQKQRV 150
Cdd:TIGR02857 397 --QIAWVPQHPFLFAG-TIAENIRLARPDASDAEIRE------ALERAGLDEFVAALPqgldtpigeggAGLSGGQAQRL 467
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759  151 AVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITHDREIGEAAARQIVI 213
Cdd:TIGR02857 468 ALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRAL-AQGRTVLLVTHRLALAALADRIVVL 529
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
26-221 3.12e-28

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 106.09  E-value: 3.12e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   26 VTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNisnmtetelARVRNKEIGFVFQ------NFMLLPRLT 99
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGAS---------PGKGWRHIGYVPQrhefawDFPISVAHT 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  100 ALqNVELPLIyaGVDKKERRERSLA---ALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:TIGR03771  72 VM-SGRTGHI--GWLRRPCVADFAAvrdALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPT 148
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 446531759  177 STQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:TIGR03771 149 QELLTELFIELAGAGTAILMTTHDLAQAMATCDRVVLLNGRVIAD 193
cbiO PRK13643
energy-coupling factor transporter ATPase;
1-199 5.41e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 107.13  E-value: 5.41e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQ-NGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELAR 79
Cdd:PRK13643   1 MIKFEKVNYTYQpNSPFASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRNKEIGFVFQ-NFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRA-THLPNELSGGQKQRVAVARAIV 157
Cdd:PRK13643  81 PVRKKVGVVFQfPESQLFEETVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADEFwEKSPFELSGGQMRRVAIAGILA 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:PRK13643 161 MEPEVLVLDEPTAGLDPKARIEMMQLFESIHQSGQTVVLVTH 202
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
20-219 6.48e-28

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 106.25  E-value: 6.48e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnkEIGFVFQNFMLLPRLT 99
Cdd:PRK11231  17 ILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLAR----RLALLPQHHLTPEGIT 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQNVEL---P-LIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTK 175
Cdd:PRK11231  93 VRELVAYgrsPwLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDIN 172
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446531759 176 TSTQIMDLFYELNKQGSTIIMITHDReigEAAARQ----IVIRDGNIV 219
Cdd:PRK11231 173 HQVELMRLMRELNTQGKTVVTVLHDL---NQASRYcdhlVVLANGHVM 217
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
12-220 7.80e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 107.63  E-value: 7.80e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  12 QNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYEL----AGQNISNMTETELARVRN----- 82
Cdd:PRK13631  33 EKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyIGDKKNNHELITNPYSKKiknfk 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  83 ---KEIGFVFQ--NFMLLpRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADraTHL---PNELSGGQKQRVAVAR 154
Cdd:PRK13631 113 elrRRVSMVFQfpEYQLF-KDTIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDD--SYLersPFGLSGGQKRRVAIAG 189
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 155 AIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDRE-IGEAAARQIVIRDGNIVQ 220
Cdd:PRK13631 190 ILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEhVLEVADEVIVMDKGKILK 256
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
20-200 8.02e-28

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 110.14  E-value: 8.02e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   20 ILHGIDVTLNQGEFTSIMGPSGSGKSTL-MNIIGCLDkPTTGTYELAGQNISNMTETELARVrnkeIGFVFQNfmllPRL 98
Cdd:TIGR02868 350 VLDGVSLDLPPGERVAILGPSGSGKSTLlATLAGLLD-PLQGEVTLDGVPVSSLDQDEVRRR----VSVCAQD----AHL 420
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   99 ---TALQNVELpliyAGVDKKErrERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVNNPKFIL 164
Cdd:TIGR02868 421 fdtTVRENLRL----ARPDATD--EELWAALERVGLADWLRALPDgldtvlgeggaRLSGGERQRLALARALLADAPILL 494
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 446531759  165 ADEPTGALDTKTSTQIM-DLFYELnkQGSTIIMITHD 200
Cdd:TIGR02868 495 LDEPTEHLDAETADELLeDLLAAL--SGRTVVLITHH 529
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
5-220 1.43e-27

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 105.39  E-value: 1.43e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   5 KGITKSFQNGAEsvqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGT--YELAG---QNISNMTETELAR 79
Cdd:PRK11701  10 RGLTKLYGPRKG----CRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEvhYRMRDgqlRDLYALSEAERRR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRNKEIGFVFQNFM--LLPRLTALQNVELPLIYAGVDKKER-RERSLAALTKVGL-ADRATHLPNELSGGQKQRVAVARA 155
Cdd:PRK11701  86 LLRTEWGFVHQHPRdgLRMQVSAGGNIGERLMAVGARHYGDiRATAGDWLERVEIdAARIDDLPTTFSGGMQQRLQIARN 165
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 156 IVNNPKFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHDreIGEA---AARQIVIRDGNIVQ 220
Cdd:PRK11701 166 LVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLvRELGLAVVIVTHD--LAVArllAHRLLVMKQGRVVE 232
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
17-220 1.43e-27

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 109.81  E-value: 1.43e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   17 SVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnkEIGFVFQNFMLLP 96
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHR----QVALVGQEPVLFS 568
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   97 RlTALQNvelplIYAGVDKKERrERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:TIGR00958 569 G-SVREN-----IAYGLTDTPD-EEIMAAAKAANAHDFIMEFPNgydtevgekgsQLSGGQKQRIAIARALVRKPRVLIL 641
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759  166 DEPTGALDtktsTQIMDLFYELNKQGS-TIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:TIGR00958 642 DEATSALD----AECEQLLQESRSRASrTVLLIAHRLSTVERADQILVLKKGSVVE 693
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
2-219 1.49e-27

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 103.90  E-value: 1.49e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmtetelARVR 81
Cdd:cd03269    1 LEVENVTKRFG----RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLD-------IAAR 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKeIGFVFQNFMLLPRLTALQNvelpLIY----AGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIV 157
Cdd:cd03269   70 NR-IGYLPEERGLYPKMKVIDQ----LVYlaqlKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVI 144
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDRE-IGEAAARQIVIRDGNIV 219
Cdd:cd03269  145 HDPELLILDEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMElVEELCDRVLLLNKGRAV 207
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
10-221 1.62e-27

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 104.62  E-value: 1.62e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  10 SFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmtETELARVRNKeIGFVF 89
Cdd:cd03251    7 TFRYPGDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVR---DYTLASLRRQ-IGLVS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  90 QNFMLLPRlTALQNVElpliYAGVDkkERRERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVN 158
Cdd:cd03251   83 QDVFLFND-TVAENIA----YGRPG--ATREEVEEAARAANAHEFIMELPEgydtvigergvKLSGGQRQRIAIARALLK 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 159 NPKFILADEPTGALDTKTSTQIMDLFYELNKqGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:cd03251  156 DPPILILDEATSALDTESERLVQAALERLMK-NRTTFVIAHRLSTIENADRIVVLEDGKIVER 217
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
19-169 2.23e-27

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 104.14  E-value: 2.23e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnKEIGFVFQNFMLLPRL 98
Cdd:TIGR03410  14 HILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERAR---AGIAYVPQGREIFPRL 90
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759   99 TALQNVELPLIYAGVDKKERRERSLA---ALTKVgLADRAthlpNELSGGQKQRVAVARAIVNNPKFILADEPT 169
Cdd:TIGR03410  91 TVEENLLTGLAALPRRSRKIPDEIYElfpVLKEM-LGRRG----GDLSGGQQQQLAIARALVTRPKLLLLDEPT 159
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
10-221 3.37e-27

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 103.72  E-value: 3.37e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  10 SFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnkEIGFVF 89
Cdd:cd03252    7 RFRYKPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRR----QVGVVL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  90 QNFMLLPRlTALQNVELpliyagVDKKERRERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVN 158
Cdd:cd03252   83 QENVLFNR-SIRDNIAL------ADPGMSMERVIEAAKLAGAHDFISELPEgydtivgeqgaGLSGGQRQRIAIARALIH 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 159 NPKFILADEPTGALDTKTSTQIMDLFYELNKqGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:cd03252  156 NPRILIFDEATSALDYESEHAIMRNMHDICA-GRTVIIIAHRLSTVKNADRIIVMEKGRIVEQ 217
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
1-219 4.97e-27

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 107.83  E-value: 4.97e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTEtelARV 80
Cdd:PRK15439  11 LLCARSISKQYS----GVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTP---AKA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLTALQNvelplIYAGVDKKERRERSLAALtkvgLADRATHLPNELSGG-----QKQRVAVARA 155
Cdd:PRK15439  84 HQLGIYLVPQEPLLFPNLSVKEN-----ILFGLPKRQASMQKMKQL----LAALGCQLDLDSSAGslevaDRQIVEILRG 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 156 IVNNPKFILADEPTGALdtkTSTQIMDLF---YELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:PRK15439 155 LMRDSRILILDEPTASL---TPAETERLFsriRELLAQGVGIVFISHKlPEIRQLADRISVMRDGTIA 219
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
2-221 5.45e-27

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 108.03  E-value: 5.45e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    2 INLKGITKSFQNgaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvr 81
Cdd:TIGR03375 464 IEFRNVSFAYPG--QETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADLRR-- 539
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   82 nkEIGFVFQNfmllPRL---TALQNVELPLIYAgvdkkeRRERSLAALTKVGLADRATHLPN-----------ELSGGQK 147
Cdd:TIGR03375 540 --NIGYVPQD----PRLfygTLRDNIALGAPYA------DDEEILRAAELAGVTEFVRRHPDgldmqigergrSLSGGQR 607
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759  148 QRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDlfyELNK--QGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:TIGR03375 608 QAVALARALLRDPPILLLDEPTSAMDNRSEERFKD---RLKRwlAGKTLVLVTHRTSLLDLVDRIIVMDNGRIVAD 680
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
10-221 1.13e-26

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 100.85  E-value: 1.13e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  10 SFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETelarvRNKEIGFVF 89
Cdd:cd03247    7 SFSYPEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKA-----LSSLISVLN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  90 QNFMLLPRlTALQNVELPLiyagvdkkerrerslaaltkvgladrathlpnelSGGQKQRVAVARAIVNNPKFILADEPT 169
Cdd:cd03247   82 QRPYLFDT-TLRNNLGRRF----------------------------------SGGERQRLALARILLQDAPIVLLDEPT 126
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446531759 170 GALDTKTSTQIMDLFYELNKqGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:cd03247  127 VGLDPITERQLLSLIFEVLK-DKTLIWITHHLTGIEHMDKILFLENGKIIMQ 177
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1-219 1.34e-26

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 106.41  E-value: 1.34e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARV 80
Cdd:PRK09700   5 YISMAGIGKSFG----PVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 rnkEIGFVFQNFMLLPRLTALQNvelplIYAG------------VDKKERRERSLAALTKVGLADRATHLPNELSGGQKQ 148
Cdd:PRK09700  81 ---GIGIIYQELSVIDELTVLEN-----LYIGrhltkkvcgvniIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQ 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 149 RVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:PRK09700 153 MLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKlAEIRRICDRYTVMKDGSSV 224
cbiO PRK13644
energy-coupling factor transporter ATPase;
1-219 1.55e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 103.14  E-value: 1.55e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESvqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARv 80
Cdd:PRK13644   1 MIRLENVSYSYPDGTPA---LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIR- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 rnKEIGFVFQN--FMLLPRLT------ALQNVELPLIyagvdkkERRERSLAALTKVGLADRATHLPNELSGGQKQRVAV 152
Cdd:PRK13644  77 --KLVGIVFQNpeTQFVGRTVeedlafGPENLCLPPI-------EIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVAL 147
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 153 ARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIV 219
Cdd:PRK13644 148 AGILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLEELHDADRIIVMDRGKIV 214
cbiO PRK13645
energy-coupling factor transporter ATPase;
21-219 1.73e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 103.16  E-value: 1.73e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNI-SNMTE-TELARVRnKEIGFVFQ--NFMLLP 96
Cdd:PRK13645  27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpANLKKiKEVKRLR-KEIGLVFQfpEYQLFQ 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 RlTALQNVELPLIYAGVDKKERRERSLAALTKVGLA-DRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTK 175
Cdd:PRK13645 106 E-TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLPeDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPK 184
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446531759 176 TSTQIMDLFYELNK-QGSTIIMITHDR-EIGEAAARQIVIRDGNIV 219
Cdd:PRK13645 185 GEEDFINLFERLNKeYKKRIIMVTHNMdQVLRIADEVIVMHEGKVI 230
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
20-211 2.21e-26

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 100.90  E-value: 2.21e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmtetELARVRNKEIGFVFQNFMLLPRLT 99
Cdd:TIGR01189  15 LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLA-----EQRDEPHENILYLGHLPGLKPELS 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  100 ALQNVELpliYAGVDKKERRErSLAALTKVGLADRAtHLP-NELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTST 178
Cdd:TIGR01189  90 ALENLHF---WAAIHGGAQRT-IEDALAAVGLTGFE-DLPaAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVA 164
                         170       180       190
                  ....*....|....*....|....*....|...
gi 446531759  179 QIMDLFYELNKQGSTIIMITHdREIGEAAARQI 211
Cdd:TIGR01189 165 LLAGLLRAHLARGGIVLLTTH-QDLGLVEAREL 196
COG4674 COG4674
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
4-205 2.55e-26

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443710 [Multi-domain]  Cd Length: 250  Bit Score: 101.73  E-value: 2.55e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRnk 83
Cdd:COG4674   13 VEDLTVSF----DGFKALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGLDEHEIARLG-- 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 eIGFVFQNFMLLPRLTALQNVEL---------PLIYAGVDKkERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVAR 154
Cdd:COG4674   87 -IGRKFQKPTVFEELTVFENLELalkgdrgvfASLFARLTA-EERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIGM 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 155 AIVNNPKFILADEPT-GALDTKTStQIMDLFYELNKQgSTIIMITHD----REIGE 205
Cdd:COG4674  165 LLAQDPKLLLLDEPVaGMTDAETE-RTAELLKSLAGK-HSVVVVEHDmefvRQIAR 218
cbiO PRK13642
energy-coupling factor transporter ATPase;
18-221 2.80e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 102.48  E-value: 2.80e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  18 VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnkEIGFVFQN----FM 93
Cdd:PRK13642  20 VNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRR----KIGMVFQNpdnqFV 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  94 llpRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:PRK13642  96 ---GATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLD 172
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446531759 174 TKTSTQIMDLFYEL-NKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:PRK13642 173 PTGRQEIMRVIHEIkEKYQLTVLSITHDLDEAASSDRILVMKAGEIIKE 221
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
1-218 3.26e-26

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 104.54  E-value: 3.26e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARv 80
Cdd:PRK09536   3 MIDVSDLSVEFG----DTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASR- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 rnkEIGFVFQNFMLLPRLTALQNVEL---PLI--YAGVDKKERR--ERSLAALTKVGLADRAThlpNELSGGQKQRVAVA 153
Cdd:PRK09536  78 ---RVASVPQDTSLSFEFDVRQVVEMgrtPHRsrFDTWTETDRAavERAMERTGVAQFADRPV---TSLSGGERQRVLLA 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIgeaAARQ----IVIRDGNI 218
Cdd:PRK09536 152 RALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDL---AARYcdelVLLADGRV 217
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
4-199 4.45e-26

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 100.81  E-value: 4.45e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKpttGTYELAGQNISNMTETELARVRnK 83
Cdd:cd03234    6 WWDVGLKAKNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVE---GGGTTSGQILFNGQPRKPDQFQ-K 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPRLTalqnVELPLIYAGV-------DKKERRER-SLAALTKVGLADRATHLPNELSGGQKQRVAVARA 155
Cdd:cd03234   82 CVAYVRQDDILLPGLT----VRETLTYTAIlrlprksSDAIRKKRvEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQ 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 446531759 156 IVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:cd03234  158 LLWDPKVLILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIH 201
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
20-220 6.82e-26

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 100.89  E-value: 6.82e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNI---SNMTETELARVRnKEIGFVFQNFMLLP 96
Cdd:PRK14246  25 ILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLyfgKDIFQIDAIKLR-KEVGMVFQQPNPFP 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 RLTALQNVELPLIYAGV-DKKERRERSLAALTKVGL----ADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGA 171
Cdd:PRK14246 104 HLSIYDNIAYPLKSHGIkEKREIKKIVEECLRKVGLwkevYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSM 183
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 446531759 172 LDTKTSTQIMDLFYELNKQgSTIIMITHD-REIGEAAARQIVIRDGNIVQ 220
Cdd:PRK14246 184 IDIVNSQAIEKLITELKNE-IAIVIVSHNpQQVARVADYVAFLYNGELVE 232
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
20-206 6.85e-26

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 99.56  E-value: 6.85e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmtETELARVRNKEIGFvfQNFMLlPRLT 99
Cdd:PRK13539  17 LFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDI----DDPDVAEACHYLGH--RNAMK-PALT 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQNVELpliYAGVdKKERRERSLAALTKVGLADrATHLP-NELSGGQKQRVAVAR-AIVNNPKFILaDEPTGALDTKTS 177
Cdd:PRK13539  90 VAENLEF---WAAF-LGGEELDIAAALEAVGLAP-LAHLPfGYLSAGQKRRVALARlLVSNRPIWIL-DEPTAALDAAAV 163
                        170       180       190
                 ....*....|....*....|....*....|
gi 446531759 178 TQIMDLFYELNKQGSTIIMITH-DREIGEA 206
Cdd:PRK13539 164 ALFAELIRAHLAQGGIVIAATHiPLGLPGA 193
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
20-220 7.58e-26

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 104.44  E-value: 7.58e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNII-GCLdKPTTGTYELAGQNISNMTETELARVrnkeIGFvfqnfmlLPrl 98
Cdd:COG4618  347 ILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLvGVW-PPTAGSVRLDGADLSQWDREELGRH----IGY-------LP-- 412
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  99 talQNVELpliYAG-----------VDkkerRERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAI 156
Cdd:COG4618  413 ---QDVEL---FDGtiaeniarfgdAD----PEKVVAAAKLAGVHEMILRLPDgydtrigeggaRLSGGQRQRIGLARAL 482
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:COG4618  483 YGDPRLVVLDEPNSNLDDEGEAALAAAIRALKARGATVVVITHRPSLLAAVDKLLVLRDGRVQA 546
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
16-220 1.30e-25

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 99.76  E-value: 1.30e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  16 ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDK--PTTGTYELAGQNISNMTETELARvrnKEIGFVFQ--- 90
Cdd:COG0396   11 EGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKyeVTSGSILLDGEDILELSPDERAR---AGIFLAFQypv 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  91 ------NFMLLprLTALQNVELPLIYAGVDKKERRErslaALTKVGL----ADRAThlpNE-LSGGQKQRVAVARAIVNN 159
Cdd:COG0396   88 eipgvsVSNFL--RTALNARRGEELSAREFLKLLKE----KMKELGLdedfLDRYV---NEgFSGGEKKRNEILQMLLLE 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 160 PKFILADEPTGALDTKtSTQIM-DLFYELNKQGSTIIMITHDREIGE--AAARQIVIRDGNIVQ 220
Cdd:COG0396  159 PKLAILDETDSGLDID-ALRIVaEGVNKLRSPDRGILIITHYQRILDyiKPDFVHVLVDGRIVK 221
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
3-218 1.47e-25

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 99.47  E-value: 1.47e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   3 NLKGITKsFQNGAES------VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETE 76
Cdd:cd03248    7 HLKGIVK-FQNVTFAyptrpdTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKY 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  77 LARVrnkeIGFVFQNFMLLPRLTA------LQNVELPLIYAGVDKKErrERSLAALTKVGLADRATHLPNELSGGQKQRV 150
Cdd:cd03248   86 LHSK----VSLVGQEPVLFARSLQdniaygLQSCSFECVKEAAQKAH--AHSFISELASGYDTEVGEKGSQLSGGQKQRV 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 151 AVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNkQGSTIIMITHDREIGEAAARQIVIRDGNI 218
Cdd:cd03248  160 AIARALIRNPQVLILDEATSALDAESEQQVQQALYDWP-ERRTVLVIAHRLSTVERADQILVLDGGRI 226
cbiO PRK13640
energy-coupling factor transporter ATPase;
20-219 1.80e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 100.26  E-value: 1.80e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNKeIGFVFQN----FMll 95
Cdd:PRK13640  22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNSKITVDGITLTAKTVWDIREK-VGIVFQNpdnqFV-- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  96 pRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTK 175
Cdd:PRK13640  99 -GATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPA 177
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446531759 176 TSTQIMDLFYEL-NKQGSTIIMITHDREIGEAAARQIVIRDGNIV 219
Cdd:PRK13640 178 GKEQILKLIRKLkKKNNLTVISITHDIDEANMADQVLVLDDGKLL 222
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
1-203 2.04e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 100.31  E-value: 2.04e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESvqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsNMTETELARV 80
Cdd:PRK13636   5 ILKVEELNYNYSDGTHA---LKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPI-DYSRKGLMKL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RnKEIGFVFQN-FMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLA---DRATHLpneLSGGQKQRVAVARAI 156
Cdd:PRK13636  81 R-ESVGMVFQDpDNQLFSASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEhlkDKPTHC---LSFGQKKRVAIAGVL 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDREI 203
Cdd:PRK13636 157 VMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDI 204
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
20-219 2.61e-25

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 99.68  E-value: 2.61e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnkEIGFVFQNFMLLPRLT 99
Cdd:PRK10253  22 VAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVAR----RIGLLAQNATTPGDIT 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQNV------ELPLIYAGvdKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:PRK10253  98 VQELVargrypHQPLFTRW--RKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLD 175
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446531759 174 TKTSTQIMDLFYELNK-QGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:PRK10253 176 ISHQIDLLELLSELNReKGYTLAAVLHDlNQACRYASHLIALREGKIV 223
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
1-218 4.28e-25

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 98.18  E-value: 4.28e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQngaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARv 80
Cdd:COG1137    3 TLEAENLVKSYG----KRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRAR- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 rnKEIGF------VFQnfmllpRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVAR 154
Cdd:COG1137   78 --LGIGYlpqeasIFR------KLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIAR 149
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 155 AIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGstI-IMIT-HD-REIGEAAARQIVIRDGNI 218
Cdd:COG1137  150 ALATNPKFILLDEPFAGVDPIAVADIQKIIRHLKERG--IgVLITdHNvRETLGICDRAYIISEGKV 214
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
20-218 4.71e-25

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 102.04  E-value: 4.71e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELArvrnKEIGFVFQNFMLLPRlT 99
Cdd:TIGR01842 333 TLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFG----KHIGYLPQDVELFPG-T 407
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  100 ALQNVelpliyAGVDKKERRERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVNNPKFILADEP 168
Cdd:TIGR01842 408 VAENI------ARFGENADPEKIIEAAKLAGVHELILRLPDgydtvigpggaTLSGGQRQRIALARALYGDPKLVVLDEP 481
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 446531759  169 TGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNI 218
Cdd:TIGR01842 482 NSNLDEEGEQALANAIKALKARGITVVVITHRPSLLGCVDKILVLQDGRI 531
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
1-216 5.35e-25

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 101.83  E-value: 5.35e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    1 MINLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIgCLDKPtTGTYE----LAGQNI--SNMTE 74
Cdd:TIGR02633   1 LLEMKGIVKTF----GGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKIL-SGVYP-HGTWDgeiyWSGSPLkaSNIRD 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   75 TElarvrNKEIGFVFQNFMLLPRLTALQNV----ELPLIYAGVDKKERRERSLAALTKVGLADRATHLP-NELSGGQKQR 149
Cdd:TIGR02633  75 TE-----RAGIVIIHQELTLVPELSVAENIflgnEITLPGGRMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQL 149
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759  150 VAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQI-VIRDG 216
Cdd:TIGR02633 150 VEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTIcVIRDG 217
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
18-220 6.96e-25

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 101.86  E-value: 6.96e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  18 VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRnKEIGFVFQN--FMLL 95
Cdd:PRK10261 337 VHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALR-RDIQFIFQDpyASLD 415
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  96 PRLTALQNVELPLIYAGV-DKKERRERSLAALTKVGL-ADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:PRK10261 416 PRQTVGDSIMEPLRVHGLlPGKAAAARVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALD 495
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446531759 174 TKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQI-VIRDGNIVQ 220
Cdd:PRK10261 496 VSIRGQIINLLLDLQRDfGIAYLFISHDMAVVERISHRVaVMYLGQIVE 544
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
1-224 8.74e-25

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 98.32  E-value: 8.74e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGA-----ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTet 75
Cdd:PRK15112   4 LLEVRNLSKTFRYRTgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGD-- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  76 elARVRNKEIGFVFQN--FMLLPRLTALQNVELPLIY-AGVDKKERRERSLAALTKVGL-ADRATHLPNELSGGQKQRVA 151
Cdd:PRK15112  82 --YSYRSQRIRMIFQDpsTSLNPRQRISQILDFPLRLnTDLEPEQREKQIIETLRQVGLlPDHASYYPHMLAPGQKQRLG 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 152 VARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELN-KQGSTIIMITHDREIGEAAARQI-VIRDGNIVQdwRG 224
Cdd:PRK15112 160 LARALILRPKVIIADEALASLDMSMRSQLINLMLELQeKQGISYIYVTQHLGMMKHISDQVlVMHQGEVVE--RG 232
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
20-223 9.72e-25

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 101.42  E-value: 9.72e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELagqnisnmteTELARVrnkeigfvfqnfMLLPrlt 99
Cdd:COG4178  378 LLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR----------PAGARV------------LFLP--- 432
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 alQNVELP-------LIYAGVDKKERRERSLAALTKVGLADRATHL------PNELSGGQKQRVAVARAIVNNPKFILAD 166
Cdd:COG4178  433 --QRPYLPlgtlreaLLYPATAEAFSDAELREALEAVGLGHLAERLdeeadwDQVLSLGEQQRLAFARLLLHKPDWLFLD 510
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 167 EPTGALDTKTSTQIMDLFYElNKQGSTIIMITHDREIGEAAARQIVIRDGnivQDWR 223
Cdd:COG4178  511 EATSALDEENEAALYQLLRE-ELPGTTVISVGHRSTLAAFHDRVLELTGD---GSWQ 563
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
18-220 1.15e-24

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 101.03  E-value: 1.15e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   18 VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYE-LAGQNISNMTET-ELARVRNKE-IGFVFQNFML 94
Cdd:TIGR03269 297 VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNvRVGDEWVDMTKPgPDGRGRAKRyIGILHQEYDL 376
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   95 LPRLTALQN------VELPLIYAgvdkkerRERSLAALTKVGLADRAT-----HLPNELSGGQKQRVAVARAIVNNPKFI 163
Cdd:TIGR03269 377 YPHRTVLDNlteaigLELPDELA-------RMKAVITLKMVGFDEEKAeeildKYPDELSEGERHRVALAQVLIKEPRIV 449
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759  164 LADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHDRE-IGEAAARQIVIRDGNIVQ 220
Cdd:TIGR03269 450 ILDEPTGTMDPITKVDVTHSILKAREEmEQTFIIVSHDMDfVLDVCDRAALMRDGKIVK 508
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
2-219 1.34e-24

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 101.05  E-value: 1.34e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELarvR 81
Cdd:PRK11160 339 LTLNNVSFTYPDQPQPV--LKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAAL---R 413
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKeIGFVFQNFMLLPRlTALQNVELpliyagVDKKERRERSLAALTKVGLAdraTHLPNE-------------LSGGQKQ 148
Cdd:PRK11160 414 QA-ISVVSQRVHLFSA-TLRDNLLL------AAPNASDEALIEVLQQVGLE---KLLEDDkglnawlgeggrqLSGGEQR 482
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 149 RVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITHdREIGEAAARQI-VIRDGNIV 219
Cdd:PRK11160 483 RLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEH-AQNKTVLMITH-RLTGLEQFDRIcVMDNGQII 552
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
22-199 2.30e-24

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 95.64  E-value: 2.30e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  22 HGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmtetelARVRNKeigfVFQNFMLL------ 95
Cdd:PRK13538  18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPI--------RRQRDE----YHQDLLYLghqpgi 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  96 -PRLTALQNVelpLIYAGVDKKERRERSLAALTKVGLADRAtHLP-NELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:PRK13538  86 kTELTALENL---RFYQRLHGPGDDEALWEALAQVGLAGFE-DVPvRQLSAGQQRRVALARLWLTRAPLWILDEPFTAID 161
                        170       180
                 ....*....|....*....|....*.
gi 446531759 174 TKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:PRK13538 162 KQGVARLEALLAQHAEQGGMVILTTH 187
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
16-219 2.71e-24

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 95.29  E-value: 2.71e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  16 ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNII-GCLD-KPTTGTYELAGQNISNMTETELARvrnKEIGFVFQNfm 93
Cdd:cd03217   11 GGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTImGHPKyEVTEGEILFKGEDITDLPPEERAR---LGIFLAFQY-- 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  94 llprltalqnvelPLIYAGVdKKERRERSLaaltkvgladrathlpNE-LSGGQKQRVAVARAIVNNPKFILADEPTGAL 172
Cdd:cd03217   86 -------------PPEIPGV-KNADFLRYV----------------NEgFSGGEKKRNEILQLLLLEPDLAILDEPDSGL 135
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446531759 173 DTKTSTQIMDLFYELNKQGSTIIMITHDREIGEA--AARQIVIRDGNIV 219
Cdd:cd03217  136 DIDALRLVAEVINKLREEGKSVLIITHYQRLLDYikPDRVHVLYDGRIV 184
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
4-216 4.01e-24

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 99.23  E-value: 4.01e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIgCLDKPTtGTYE----LAGQNI--SNMTETEl 77
Cdd:PRK13549   8 MKNITKTF----GGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVL-SGVYPH-GTYEgeiiFEGEELqaSNIRDTE- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  78 arvrNKEIGFVFQNFMLLPRLTALQNVEL--PLIYAGV-DKKERRERSLAALTKVGLaDRATHLP-NELSGGQKQRVAVA 153
Cdd:PRK13549  81 ----RAGIAIIHQELALVKELSVLENIFLgnEITPGGImDYDAMYLRAQKLLAQLKL-DINPATPvGNLGLGQQQLVEIA 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQI-VIRDG 216
Cdd:PRK13549 156 KALNKQARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTIcVIRDG 219
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
4-220 4.98e-24

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 99.22  E-value: 4.98e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQnisnmtETELARVR-- 81
Cdd:PRK11288   7 FDGIGKTF----PGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQ------EMRFASTTaa 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 -NKEIGFVFQNFMLLPRLTALQNV---ELPLIYAGVDKKERRERSLAALTKVGLA-DRATHLpNELSGGQKQRVAVARAI 156
Cdd:PRK11288  77 lAAGVAIIYQELHLVPEMTVAENLylgQLPHKGGIVNRRLLNYEAREQLEHLGVDiDPDTPL-KYLSIGQRQMVEIAKAL 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHdR--EIGEAAARQIVIRDGNIVQ 220
Cdd:PRK11288 156 ARNARVIAFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSH-RmeEIFALCDAITVFKDGRYVA 220
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
4-224 5.42e-24

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 98.98  E-value: 5.42e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFqnGAEsvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAgqnisnmtetelarvRNK 83
Cdd:COG0488    1 LENLSKSF--GGR--PLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIP---------------KGL 61
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPRLTALQNVE--LPLIYAGVDKKERRERSLA------------------------------ALTKVGL 131
Cdd:COG0488   62 RIGYLPQEPPLDDDLTVLDTVLdgDAELRALEAELEELEAKLAepdedlerlaelqeefealggweaearaeeILSGLGF 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 132 ADRATHLP-NELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTstqIMDLfyE--LNKQGSTIIMITHDREIGEAAA 208
Cdd:COG0488  142 PEEDLDRPvSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLES---IEWL--EefLKNYPGTVLVVSHDRYFLDRVA 216
                        250
                 ....*....|....*.
gi 446531759 209 RQIVIRDGNIVQDWRG 224
Cdd:COG0488  217 TRILELDRGKLTLYPG 232
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
20-220 1.17e-23

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 94.77  E-value: 1.17e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKStlMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNKEIGFVFQNfmllPRlT 99
Cdd:PRK10418  18 LVHGVSLTLQRGRVLALVGGSGSGKS--LTCAAALGILPAGVRQTAGRVLLDGKPVAPCALRGRKIATIMQN----PR-S 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQNVELPLIYA-----GVDKKERRERSLAALTKVGLADRATHL---PNELSGGQKQRVAVARAIVNNPKFILADEPTGA 171
Cdd:PRK10418  91 AFNPLHTMHTHAretclALGKPADDATLTAALEAVGLENAARVLklyPFEMSGGMLQRMMIALALLCEAPFIIADEPTTD 170
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446531759 172 LDTKTSTQIMDLFYEL-NKQGSTIIMITHDREIGEAAARQI-VIRDGNIVQ 220
Cdd:PRK10418 171 LDVVAQARILDLLESIvQKRALGMLLVTHDMGVVARLADDVaVMSHGRIVE 221
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
23-200 1.40e-23

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 94.67  E-value: 1.40e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  23 GIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELAR---VRnkeigfVFQNFMLLPRLT 99
Cdd:PRK11300  23 NVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARmgvVR------TFQHVRLFREMT 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQN--------VELPLIyAGVDK--------KERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFI 163
Cdd:PRK11300  97 VIENllvaqhqqLKTGLF-SGLLKtpafrraeSEALDRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEIL 175
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446531759 164 LADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD 200
Cdd:PRK11300 176 MLDEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHD 213
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
19-220 1.73e-23

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 97.99  E-value: 1.73e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHG-IDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCLdkPTTGTYELAGQNISNMtetELARVRnKEIGFVFQNfMLLP 96
Cdd:PRK11174 363 KTLAGpLNFTLPAGQRIALVGPSGAGKTSLLNaLLGFL--PYQGSLKINGIELREL---DPESWR-KHLSWVGQN-PQLP 435
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 RLTALQNVELpliyAGVDKKErrERSLAALTKVGLADRATHLPN-----------ELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:PRK11174 436 HGTLRDNVLL----GNPDASD--EQLQQALENAWVSEFLPLLPQgldtpigdqaaGLSVGQAQRLALARALLQPCQLLLL 509
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 166 DEPTGALDTKTSTQIMDLFYElNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:PRK11174 510 DEPTASLDAHSEQLVMQALNA-ASRRQTTLMVTHQLEDLAQWDQIWVMQDGQIVQ 563
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
2-205 2.08e-23

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 96.05  E-value: 2.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAesvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmTETELARVR 81
Cdd:PRK13536  42 IDLAGVSKSYGDKA----VVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVP--ARARLARAR 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nkeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:PRK13536 116 ---IGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQ 192
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGE 205
Cdd:PRK13536 193 LLILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAE 236
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
1-219 3.10e-23

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 97.06  E-value: 3.10e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELaGQNIsnmtetelarv 80
Cdd:COG0488  315 VLELEGLSKSY----GDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV----------- 378
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 rnkEIGFVFQNFMLL-PRLTALQNVElpliYAGVDKKERRERSLA---------ALTKVGladrathlpnELSGGQKQRV 150
Cdd:COG0488  379 ---KIGYFDQHQEELdPDKTVLDELR----DGAPGGTEQEVRGYLgrflfsgddAFKPVG----------VLSGGEKARL 441
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 151 AVARAIVNNPKFILADEPTGALDTKTSTQIMDLfyeLNKQGSTIIMITHDRE-IGEAAARQIVIRDGNIV 219
Cdd:COG0488  442 ALAKLLLSPPNVLLLDEPTNHLDIETLEALEEA---LDDFPGTVLLVSHDRYfLDRVATRILEFEDGGVR 508
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
2-221 9.62e-23

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 91.83  E-value: 9.62e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSF------------------QNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYE 63
Cdd:cd03220    1 IELENVSKSYptykggssslkklgilgrKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  64 LAGQNISNMtetelarvrnkEIGFVFQnfmllPRLTALQNVELPLIYAGVDKKERRER-----SLAALTKVGladratHL 138
Cdd:cd03220   81 VRGRVSSLL-----------GLGGGFN-----PELTGRENIYLNGRLLGLSRKEIDEKideiiEFSELGDFI------DL 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 139 P-NELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDG 216
Cdd:cd03220  139 PvKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDpSSIKRLCDRALVLEKG 218

                 ....*
gi 446531759 217 NIVQD 221
Cdd:cd03220  219 KIRFD 223
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
20-219 2.93e-22

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 91.39  E-value: 2.93e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnkEIGFVFQNfmlLPRLT 99
Cdd:PRK10575  26 LLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFAR----KVAYLPQQ---LPAAE 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQNVELPLI--YA-----GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGAL 172
Cdd:PRK10575  99 GMTVRELVAIgrYPwhgalGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSAL 178
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446531759 173 DTKTSTQIMDLFYELNKQ-GSTIIMITHDREIgeaAARQ----IVIRDGNIV 219
Cdd:PRK10575 179 DIAHQVDVLALVHRLSQErGLTVIAVLHDINM---AARYcdylVALRGGEMI 227
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
17-219 4.42e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 91.40  E-value: 4.42e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  17 SVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmTETELARVRnKEIGFVFQN---FM 93
Cdd:PRK13652  16 SKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPI---TKENIREVR-KFVGLVFQNpddQI 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  94 LLPrlTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:PRK13652  92 FSP--TVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLD 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446531759 174 TKTSTQIMDLFYELNKQ-GSTIIMITHDRE-IGEAAARQIVIRDGNIV 219
Cdd:PRK13652 170 PQGVKELIDFLNDLPETyGMTVIFSTHQLDlVPEMADYIYVMDKGRIV 217
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
12-216 5.31e-22

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 89.45  E-value: 5.31e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  12 QNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCLDKpTTGTYELAGQnisnmtetelarvrnkeIGFVFQ 90
Cdd:cd03250   12 SGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSaLLGELEK-LSGSVSVPGS-----------------IAYVSQ 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  91 NFMLLPRlTALQNVELPLIYagvdKKERRERSLAA--------------LTKVGladrathlpnE----LSGGQKQRVAV 152
Cdd:cd03250   74 EPWIQNG-TIRENILFGKPF----DEERYEKVIKAcalepdleilpdgdLTEIG----------EkginLSGGQKQRISL 138
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 153 ARAIVNNPKFILADEPTGALDTKTSTQIMD-LFYELNKQGSTIIMITHDREIGEAAARQIVIRDG 216
Cdd:cd03250  139 ARAVYSDADIYLLDDPLSAVDAHVGRHIFEnCILGLLLNNKTRILVTHQLQLLPHADQIVVLDNG 203
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
2-205 5.65e-22

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 91.41  E-value: 5.65e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqnGAESVqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmTETELARVR 81
Cdd:PRK13537   8 IDFRNVEKRY--GDKLV--VDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVP--SRARHARQR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nkeIGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:PRK13537  82 ---VGVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPD 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGE 205
Cdd:PRK13537 159 VLVLDEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAE 202
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
4-221 7.94e-22

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 89.70  E-value: 7.94e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGA-ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrn 82
Cdd:cd03267   19 LIGSLKSLFKRKyREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKFLRR--- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  83 keIGFVF-QNFMLLPRLTALQNVEL-PLIYaGVDKKERRER--SLAALTKVGladRATHLP-NELSGGQKQRVAVARAIV 157
Cdd:cd03267   96 --IGVVFgQKTQLWWDLPVIDSFYLlAAIY-DLPPARFKKRldELSELLDLE---ELLDTPvRQLSLGQRMRAEIAAALL 169
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD-REIGEAAARQIVIRDGNIVQD 221
Cdd:cd03267  170 HEPEILFLDEPTIGLDVVAQENIRNFLKEYNRErGTTVLLTSHYmKDIEALARRVLVIDKGRLLYD 235
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
2-221 8.13e-22

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 93.27  E-value: 8.13e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    2 INLKGITKSFQNGAEsvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVR 81
Cdd:TIGR01193 474 IVINDVSYSYGYGSN---ILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLRQFI 550
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   82 N---KE----IGFVFQNFMLlprlTALQNVELPLIYAGVD----KKERRERSLAALTKvgLADRATHLpnelSGGQKQRV 150
Cdd:TIGR01193 551 NylpQEpyifSGSILENLLL----GAKENVSQDEIWAACEiaeiKDDIENMPLGYQTE--LSEEGSSI----SGGQKQRI 620
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759  151 AVARAIVNNPKFILADEPTGALDTKTSTQIMDLFyeLNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:TIGR01193 621 ALARALLTDSKVLILDESTSNLDTITEKKIVNNL--LNLQDKTIIFVAHRLSVAKQSDKIIVLDHGKIIEQ 689
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
18-219 1.34e-21

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 89.17  E-value: 1.34e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  18 VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmTETELARVRNKEIGFVFQNFMLLPR 97
Cdd:PRK11614  18 IQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDI---TDWQTAKIMREAVAIVPEGRRVFSR 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTALQNVELPLIYAGVDK-KERRERSLAALTKvgLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:PRK11614  95 MTVEENLAMGGFFAERDQfQERIKWVYELFPR--LHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPII 172
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 446531759 177 STQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:PRK11614 173 IQQIFDTIEQLREQGMTIFLVEQNaNQALKLADRGYVLENGHVV 216
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
20-211 1.87e-21

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 87.93  E-value: 1.87e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQnisnmtetELARVRN---KEIGFVFQNFMLLP 96
Cdd:cd03231   15 LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGG--------PLDFQRDsiaRGLLYLGHAPGIKT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 RLTALQNVELpliYAGVDKKERRERSLAALTKVGLADRATHlpnELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:cd03231   87 TLSVLENLRF---WHADHSDEQVEEALARVGLNGFEDRPVA---QLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAG 160
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 446531759 177 STQIMDLFYELNKQGSTIIMITH-DREIGEAAARQI 211
Cdd:cd03231  161 VARFAEAMAGHCARGGMVVLTTHqDLGLSEAGAREL 196
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
24-213 1.93e-21

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 92.38  E-value: 1.93e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    24 IDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmtETELARVRnKEIGFVFQNFMLLPRLTALQN 103
Cdd:TIGR01257  949 LNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDI----ETNLDAVR-QSLGMCPQHNILFHHLTVAEH 1023
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   104 VelpLIYAGVDKKERRERSL---AALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQI 180
Cdd:TIGR01257 1024 I---LFYAQLKGRSWEEAQLemeAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSI 1100
                          170       180       190
                   ....*....|....*....|....*....|...
gi 446531759   181 MDLFYELnKQGSTIIMITHDREIGEAAARQIVI 213
Cdd:TIGR01257 1101 WDLLLKY-RSGRTIIMSTHHMDEADLLGDRIAI 1132
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
19-219 3.45e-21

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 91.03  E-value: 3.45e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVrnkeIGFVFQNfmllprl 98
Cdd:COG5265  372 PILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASLRAA----IGIVPQD------- 440
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  99 TALQN--VELPLIYA--GVDKKERRErslAAltkvgladRATH-------LPN-----------ELSGGQKQRVAVARAI 156
Cdd:COG5265  441 TVLFNdtIAYNIAYGrpDASEEEVEA---AA--------RAAQihdfiesLPDgydtrvgerglKLSGGEKQRVAIARTL 509
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDlfyELNK--QGSTIIMITHdR--------EIgeaaarqIVIRDGNIV 219
Cdd:COG5265  510 LKNPPILIFDEATSALDSRTERAIQA---ALREvaRGRTTLVIAH-RlstivdadEI-------LVLEAGRIV 571
GguA NF040905
sugar ABC transporter ATP-binding protein;
4-220 3.53e-21

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 91.00  E-value: 3.53e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNgaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLdKPTtGTYElaGQNISNMTETELARVRNK 83
Cdd:NF040905   4 MRGITKTFPG----VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV-YPH-GSYE--GEILFDGEVCRFKDIRDS 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 E---IGFVFQNFMLLPRLTALQNVEL---PLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIV 157
Cdd:NF040905  76 EalgIVIIHQELALIPYLSIAENIFLgneRAKRGVIDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALS 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIVQ 220
Cdd:NF040905 156 KDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKlNEIRRVADSITVLRDGRTIE 219
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
34-221 4.53e-21

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 88.61  E-value: 4.53e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  34 TSIMGPSGSGKSTLMNIIGCLDKPTTG-TYE----LAGQNISNMTETELARVRnkeIGFVFQNFMLLPrLTALQNVELPL 108
Cdd:PRK14271  50 TSLMGPTGSGKTTFLRTLNRMNDKVSGyRYSgdvlLGGRSIFNYRDVLEFRRR---VGMLFQRPNPFP-MSIMDNVLAGV 125
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 109 -IYAGVDKKERRERSLAALTKVGL----ADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDL 183
Cdd:PRK14271 126 rAHKLVPRKEFRGVAQARLTEVGLwdavKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEF 205
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 446531759 184 FYELNKQgSTIIMITHD-REIGEAAARQIVIRDGNIVQD 221
Cdd:PRK14271 206 IRSLADR-LTVIIVTHNlAQAARISDRAALFFDGRLVEE 243
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
4-216 6.68e-21

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 90.06  E-value: 6.68e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIgcldkptTGTYEL-AGQNISNMTETELARVRN 82
Cdd:PRK10762   7 LKGIDKAF----PGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVL-------TGIYTRdAGSILYLGKEVTFNGPKS 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  83 KE---IGFVFQNFMLLPRLTALQNV----ELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARA 155
Cdd:PRK10762  76 SQeagIGIIHQELNLIPQLTIAENIflgrEFVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKV 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 156 IVNNPKFILADEPTGAL-DTKTSTqimdLF---YELNKQGSTIIMITHD-REIGEAAARQIVIRDG 216
Cdd:PRK10762 156 LSFESKVIIMDEPTDALtDTETES----LFrviRELKSQGRGIVYISHRlKEIFEICDDVTVFRDG 217
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
21-218 8.42e-21

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 85.56  E-value: 8.42e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELarvRNKEIGFVfqnfmllprlta 100
Cdd:cd03215   16 VRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDA---IRAGIAYV------------ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 101 lqnvelPliyagvdkKERRERSLaaLTKVGLADRAThLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQI 180
Cdd:cd03215   81 ------P--------EDRKREGL--VLDLSVAENIA-LSSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEI 143
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 446531759 181 MDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNI 218
Cdd:cd03215  144 YRLIRELADAGKAVLLISSElDELLGLCDRILVMYEGRI 182
galliderm_ABC TIGR03740
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...
5-199 8.59e-21

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.


Pssm-ID: 163452 [Multi-domain]  Cd Length: 223  Bit Score: 86.68  E-value: 8.59e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    5 KGITKSFQNGAesvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGqniSNMTETELarvrnKE 84
Cdd:TIGR03740   4 KNLSKRFGKQT----AVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDG---HPWTRKDL-----HK 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   85 IGFVFQNFMLLPRLTALQNVELPLIYAGVDKKERRErslaALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFIL 164
Cdd:TIGR03740  72 IGSLIESPPLYENLTARENLKVHTTLLGLPDSRIDE----VLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLI 147
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 446531759  165 ADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:TIGR03740 148 LDEPTNGLDPIGIQELRELIRSFPEQGITVILSSH 182
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
2-216 1.11e-20

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 84.42  E-value: 1.11e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAgqnisnmtetelarvR 81
Cdd:cd03221    1 IELENLSKTYGGK----LLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWG---------------S 61
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVFQnfmllprltalqnvelpliyagvdkkerrerslaaltkvgladrathlpneLSGGQKQRVAVARAIVNNPK 161
Cdd:cd03221   62 TVKIGYFEQ---------------------------------------------------LSGGEKMRLALAKLLLENPN 90
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 162 FILADEPTGALDTKTSTQIMDlfyELNKQGSTIIMITHDRE-IGEAAARQIVIRDG 216
Cdd:cd03221   91 LLLLDEPTNHLDLESIEALEE---ALKEYPGTVILVSHDRYfLDQVATKIIELEDG 143
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
1-200 2.17e-20

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 86.32  E-value: 2.17e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYElagqnisnmtetelaRV 80
Cdd:PRK09544   4 LVSLENVSVSFGQR----RVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK---------------RN 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEIGFVFQNFMLLPRLtALQNVELPLIYAGVdkkeRRERSLAALTKVgladRATHLPN----ELSGGQKQRVAVARAI 156
Cdd:PRK09544  65 GKLRIGYVPQKLYLDTTL-PLTVNRFLRLRPGT----KKEDILPALKRV----QAGHLIDapmqKLSGGETQRVLLARAL 135
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446531759 157 VNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD 200
Cdd:PRK09544 136 LNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRElDCAVLMVSHD 180
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
1-220 3.94e-20

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 88.37  E-value: 3.94e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKS----TLMNIIgcldKPTTGTYELAGQ--------- 67
Cdd:PRK10261  12 VLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSvtalALMRLL----EQAGGLVQCDKMllrrrsrqv 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  68 -NISNMTETELARVRNKEIGFVFQNFM--LLPRLT-ALQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHL---PN 140
Cdd:PRK10261  88 iELSEQSAAQMRHVRGADMAMIFQEPMtsLNPVFTvGEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEAQTILsryPH 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 141 ELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGST-IIMITHDRE-IGEAAARQIVIRDGNI 218
Cdd:PRK10261 168 QLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMgVIFITHDMGvVAEIADRVLVMYQGEA 247

                 ..
gi 446531759 219 VQ 220
Cdd:PRK10261 248 VE 249
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
3-220 4.36e-20

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 88.09  E-value: 4.36e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   3 NLKG------ITKSFQNgaeSVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETE 76
Cdd:PRK13657 330 RVKGavefddVSFSYDN---SRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRAS 406
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  77 LARvrnkEIGFVFQNFMLLPRLTA--LQ-------NVELPL---IYAGVDKKERRERSLAalTKVGlaDRAthlpNELSG 144
Cdd:PRK13657 407 LRR----NIAVVFQDAGLFNRSIEdnIRvgrpdatDEEMRAaaeRAQAHDFIERKPDGYD--TVVG--ERG----RQLSG 474
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 145 GQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:PRK13657 475 GERQRLAIARALLKDPPILILDEATSALDVETEAKVKAALDEL-MKGRTTFIIAHRLSTVRNADRILVFDNGRVVE 549
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1-221 4.63e-20

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 86.29  E-value: 4.63e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSF-----QNGA------------ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNII-GCLdKPTTGTY 62
Cdd:COG4586    1 IIEVENLSKTYrvyekEPGLkgalkglfrreyREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLtGIL-VPTSGEV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  63 ELAGQNISNmTETELARvrnkEIGFVF-QNFMLLPRLTALQNVEL-PLIYaGVDKKERRERsLAALTKV----GLADRAT 136
Cdd:COG4586   80 RVLGYVPFK-RRKEFAR----RIGVVFgQRSQLWWDLPAIDSFRLlKAIY-RIPDAEYKKR-LDELVELldlgELLDTPV 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 137 HlpnELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD-REIGEAAARQIVIR 214
Cdd:COG4586  153 R---QLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRErGTTILLTSHDmDDIEALCDRVIVID 229

                 ....*..
gi 446531759 215 DGNIVQD 221
Cdd:COG4586  230 HGRIIYD 236
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
24-219 6.03e-20

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 86.47  E-value: 6.03e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  24 IDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNKEIGFVFQNFMLLPRLTALQN 103
Cdd:PRK11144  17 VNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGICLPPEKRRIGYVFQDARLFPHYKVRGN 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 104 velpLIYaGVDKKERRE-RSLAALTKVG-LADRathLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIM 181
Cdd:PRK11144  97 ----LRY-GMAKSMVAQfDKIVALLGIEpLLDR---YPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELL 168
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 446531759 182 DLFYELNKQGST-IIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:PRK11144 169 PYLERLAREINIpILYVSHSlDEILRLADRVVVLEQGKVK 208
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
19-219 6.51e-20

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 84.56  E-value: 6.51e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARvrnKEIGFVFQNFMLLPRL 98
Cdd:PRK10895  17 RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARAR---RGIGYLPQEASIFRRL 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  99 TALQNVELPL-IYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTS 177
Cdd:PRK10895  94 SVYDNLMAVLqIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISV 173
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 446531759 178 TQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:PRK10895 174 IDIKRIIEHLRDSGLGVLITDHNvRETLAVCERAYIVSQGHLI 216
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
21-200 1.63e-19

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 83.74  E-value: 1.63e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNII-GCLdkPTTGTYELAGQNISNMTETELARVRnkeiGFVFQNFMLLPRLT 99
Cdd:COG4138   12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMaGLL--PGQGEILLNGRPLSDWSAAELARHR----AYLSQQQSPPFAMP 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQnvELPLIYAGVDKKERRERSLAALT-KVGLADRATHLPNELSGGQKQRVAVARAIV-----NNP--KFILADEPTGA 171
Cdd:COG4138   86 VFQ--YLALHQPAGASSEAVEQLLAQLAeALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptINPegQLLLLDEPMNS 163
                        170       180
                 ....*....|....*....|....*....
gi 446531759 172 LDTKTSTQIMDLFYELNKQGSTIIMITHD 200
Cdd:COG4138  164 LDVAQQAALDRLLRELCQQGITVVMSSHD 192
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
9-200 1.96e-19

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 83.93  E-value: 1.96e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   9 KSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLmniIGCLDK--------PTTGTYELAGQNISNmTETELARV 80
Cdd:PRK14258  11 NNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTF---LKCLNRmnelesevRVEGRVEFFNQNIYE-RRVNLNRL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RnKEIGFVFQNFMLLPrLTALQNVELPLIYAGVDKK-ERRERSLAALTKVGLADRATHLPN----ELSGGQKQRVAVARA 155
Cdd:PRK14258  87 R-RQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWRPKlEIDDIVESALKDADLWDEIKHKIHksalDLSGGQQQRLCIARA 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446531759 156 IVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGS-TIIMITHD 200
Cdd:PRK14258 165 LAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSElTMVIVSHN 210
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
19-219 2.85e-19

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 83.52  E-value: 2.85e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTL-MNIIGCLdKPTTGTYELAGQNIsNMTETELARVRnKEIGFVFQNFMLLPR 97
Cdd:PRK13638  15 PVLKGLNLDFSLSPVTGLVGANGCGKSTLfMNLSGLL-RPQKGAVLWQGKPL-DYSKRGLLALR-QQVATVFQDPEQQIF 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTAL-QNVELPLIYAGVDKKERRERSLAALTKVGlADRATHLPNE-LSGGQKQRVAVARAIVNNPKFILADEPTGALDTK 175
Cdd:PRK13638  92 YTDIdSDIAFSLRNLGVPEAEITRRVDEALTLVD-AQHFRHQPIQcLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPA 170
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446531759 176 TSTQIMDLFYELNKQGSTIIMITHDRE-IGEAAARQIVIRDGNIV 219
Cdd:PRK13638 171 GRTQMIAIIRRIVAQGNHVIISSHDIDlIYEISDAVYVLRQGQIL 215
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
1-221 3.65e-19

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 82.82  E-value: 3.65e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQ------------------NGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTY 62
Cdd:COG1134    4 MIEVENVSKSYRlyhepsrslkelllrrrrTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  63 ELAGqNISNMteteLarvrnkEIGFVFQnfmllPRLTALQNVELP-LIYaGVDKKE--RRERSLAALTKVGladRATHLP 139
Cdd:COG1134   84 EVNG-RVSAL----L------ELGAGFH-----PELTGRENIYLNgRLL-GLSRKEidEKFDEIVEFAELG---DFIDQP 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 140 -NELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDRE-IGEAAARQIVIRDGN 217
Cdd:COG1134  144 vKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGaVRRLCDRAIWLEKGR 223

                 ....
gi 446531759 218 IVQD 221
Cdd:COG1134  224 LVMD 227
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
2-200 1.83e-18

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 81.47  E-value: 1.83e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESvqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETEL-ARV 80
Cdd:PRK15056   7 IVVNDVTVTWRNGHTA---LRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNLvAYV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 -RNKEIGFVF----QNFMLLPRLTALQNVELPliyagvdKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARA 155
Cdd:PRK15056  84 pQSEEVDWSFpvlvEDVVMMGRYGHMGWLRRA-------KKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARA 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446531759 156 IVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD 200
Cdd:PRK15056 157 IAQQGQVILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHN 201
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
1-200 3.89e-18

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 81.39  E-value: 3.89e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKP----TTGTYELAGQNISNMTETE 76
Cdd:PRK15093   3 LLDIRNLTIEFKTSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDnwrvTADRMRFDDIDLLRLSPRE 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  77 LARVRNKEIGFVFQNfmllPR--LTALQNVELPLIYA--GVDKKE--------RRERSLAALTKVGLADRA---THLPNE 141
Cdd:PRK15093  83 RRKLVGHNVSMIFQE----PQscLDPSERVGRQLMQNipGWTYKGrwwqrfgwRKRRAIELLHRVGIKDHKdamRSFPYE 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 142 LSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQ-GSTIIMITHD 200
Cdd:PRK15093 159 LTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNnNTTILLISHD 218
PLN03211 PLN03211
ABC transporter G-25; Provisional
20-199 5.14e-18

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 82.23  E-value: 5.14e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNiigcldkpttgtyELAGQ-NISNMTETELARVRN------KEIGFVFQNF 92
Cdd:PLN03211  83 ILNGVTGMASPGEILAVLGPSGSGKSTLLN-------------ALAGRiQGNNFTGTILANNRKptkqilKRTGFVTQDD 149
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  93 MLLPRLTALQN---VELPLIYAGVDKKERRERSLAALTKVGLAD-RATHLPNE----LSGGQKQRVAVARAIVNNPKFIL 164
Cdd:PLN03211 150 ILYPHLTVRETlvfCSLLRLPKSLTKQEKILVAESVISELGLTKcENTIIGNSfirgISGGERKRVSIAHEMLINPSLLI 229
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 446531759 165 ADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:PLN03211 230 LDEPTSGLDATAAYRLVLTLGSLAQKGKTIVTSMH 264
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
2-224 1.59e-17

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 80.45  E-value: 1.59e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQnGAESvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmtETELARVR 81
Cdd:PRK11176 342 IEFRNVTFTYP-GKEV-PALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLR---DYTLASLR 416
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NkEIGFVFQNFMLLPRLTAlQNVElpliYAGVDKKERRERSLAAltKVGLA-DRATHLPN-----------ELSGGQKQR 149
Cdd:PRK11176 417 N-QVALVSQNVHLFNDTIA-NNIA----YARTEQYSREQIEEAA--RMAYAmDFINKMDNgldtvigengvLLSGGQRQR 488
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 150 VAVARAIVNN-PKFILaDEPTGALDTKTSTQIMDLFYELNKQgSTIIMITHDREIGEAAARQIVIRDGNIVQdwRG 224
Cdd:PRK11176 489 IAIARALLRDsPILIL-DEATSALDTESERAIQAALDELQKN-RTSLVIAHRLSTIEKADEILVVEDGEIVE--RG 560
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
20-199 1.74e-17

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 76.42  E-value: 1.74e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNisnmtetelarvrnkeigfvfqNFMLLPRLt 99
Cdd:cd03223   16 LLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEGE----------------------DLLFLPQR- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 alqnvelPLIYAGVdkkeRRERSLAALTKVgladrathlpneLSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQ 179
Cdd:cd03223   73 -------PYLPLGT----LREQLIYPWDDV------------LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDR 129
                        170       180
                 ....*....|....*....|
gi 446531759 180 IMDLfyeLNKQGSTIIMITH 199
Cdd:cd03223  130 LYQL---LKELGITVISVGH 146
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
20-216 2.42e-17

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 77.31  E-value: 2.42e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCL-DKPTTGTYELAGQNISNmtetelarvrnkeigfvfqnfmllpr 97
Cdd:COG2401   45 VLRDLNLEIEPGEIVLIVGASGSGKSTLLRlLAGALkGTPVAGCVDVPDNQFGR-------------------------- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 ltalqnvELPLI---YAGVDKKErrerSLAALTKVGLADRATHL--PNELSGGQKQRVAVARAIVNNPKFILADEPTGAL 172
Cdd:COG2401   99 -------EASLIdaiGRKGDFKD----AVELLNAVGLSDAVLWLrrFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHL 167
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446531759 173 DTKTSTQIMDLFYELNKQ-GSTIIMITHDREIGEAAARQIVIRDG 216
Cdd:COG2401  168 DRQTAKRVARNLQKLARRaGITLVVATHHYDVIDDLQPDLLIFVG 212
sufC TIGR01978
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...
16-221 2.63e-17

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273907 [Multi-domain]  Cd Length: 243  Bit Score: 77.69  E-value: 2.63e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   16 ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNII----GCldKPTTGTYELAGQNISNMTETELARvrnKEIGFVFQN 91
Cdd:TIGR01978  11 EDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIaghpSY--EVTSGTILFKGQDLLELEPDERAR---AGLFLAFQY 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   92 FMLLPRLTAL------------QNVELPLIYAGVDKKERRERSLAALTKvGLADRAThlpNE-LSGGQKQRVAVARAIVN 158
Cdd:TIGR01978  86 PEEIPGVSNLeflrsalnarrsARGEEPLDLLDFEKLLKEKLALLDMDE-EFLNRSV---NEgFSGGEKKRNEILQMALL 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759  159 NPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIV--IRDGNIVQD 221
Cdd:TIGR01978 162 EPKLAILDEIDSGLDIDALKIVAEGINRLREPDRSFLIITHYQRLLNYIKPDYVhvLLDGRIVKS 226
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
25-200 2.66e-17

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 77.90  E-value: 2.66e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  25 DVTLN--QGEFTSIMGPSGSGKSTL------MN--IIGCldkPTTGTYELAGQNIsNMTETELARVRNKeIGFVFQNFML 94
Cdd:PRK14243  28 NVWLDipKNQITAFIGPSGCGKSTIlrcfnrLNdlIPGF---RVEGKVTFHGKNL-YAPDVDPVEVRRR-IGMVFQKPNP 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  95 LPRlTALQNVEL-PLI--YAGvDKKERRERSL--AALTKvGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPT 169
Cdd:PRK14243 103 FPK-SIYDNIAYgARIngYKG-DMDELVERSLrqAALWD-EVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDEPC 179
                        170       180       190
                 ....*....|....*....|....*....|.
gi 446531759 170 GALDTKTSTQIMDLFYELNKQgSTIIMITHD 200
Cdd:PRK14243 180 SALDPISTLRIEELMHELKEQ-YTIIIVTHN 209
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
27-200 1.02e-16

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 76.12  E-value: 1.02e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  27 TLNQGEFTSIMGPSGSGKSTLMN-IIGCLdkPTTGTYELAGQNISNMTETELARVR-----NKEIGF---VFQNFML-LP 96
Cdd:PRK03695  18 EVRAGEILHLVGPNGAGKSTLLArMAGLL--PGSGSIQFAGQPLEAWSAAELARHRaylsqQQTPPFampVFQYLTLhQP 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 RLTALQNVELPLIYagvdkkerrersLAALtkVGLADRATHLPNELSGGQKQRVAVARAI-----VNNP--KFILADEPT 169
Cdd:PRK03695  96 DKTRTEAVASALNE------------VAEA--LGLDDKLGRSVNQLSGGEWQRVRLAAVVlqvwpDINPagQLLLLDEPM 161
                        170       180       190
                 ....*....|....*....|....*....|.
gi 446531759 170 GALDTKTSTQIMDLFYELNKQGSTIIMITHD 200
Cdd:PRK03695 162 NSLDVAQQAALDRLLSELCQQGIAVVMSSHD 192
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
21-219 1.33e-16

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 77.75  E-value: 1.33e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElaRVRNKeIGFVFQNFM---LLPR 97
Cdd:COG1129  268 VRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRD--AIRAG-IAYVPEDRKgegLVLD 344
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTALQNVELPLI--YAG---VDKKERRERSLAALTKVGL-ADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGA 171
Cdd:COG1129  345 LSIRENITLASLdrLSRgglLDRRRERALAEEYIKRLRIkTPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRG 424
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446531759 172 LDTKTSTQIMDLFYELNKQGSTIIMIThdREIGEAAA---RQIVIRDGNIV 219
Cdd:COG1129  425 IDVGAKAEIYRLIRELAAEGKAVIVIS--SELPELLGlsdRILVMREGRIV 473
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
2-220 5.91e-16

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 73.22  E-value: 5.91e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFqnGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMtetELARVR 81
Cdd:cd03369    7 IEVENLSVRY--APDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTI---PLEDLR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKeIGFVFQNFMLLPRlTALQNVElplIYAGVDKKERRErslaaltkvglADRATHLPNELSGGQKQRVAVARAIVNNPK 161
Cdd:cd03369   82 SS-LTIIPQDPTLFSG-TIRSNLD---PFDEYSDEEIYG-----------ALRVSEGGLNLSQGQRQLLCLARALLKRPR 145
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 162 FILADEPTGALDTKTSTQIMDLFYELNkQGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:cd03369  146 VLVLDEATASIDYATDALIQKTIREEF-TNSTILTIAHRLRTIIDYDKILVMDAGEVKE 203
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
16-220 1.38e-15

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 72.53  E-value: 1.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  16 ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMtetELARVRNKeIGFVFQNfmll 95
Cdd:cd03244   15 NLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKI---GLHDLRSR-ISIIPQD---- 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  96 prltalqnvelPLIYAG-----VDKKERR--ERSLAALTKVGLADRATHLP-----------NELSGGQKQRVAVARAIV 157
Cdd:cd03244   87 -----------PVLFSGtirsnLDPFGEYsdEELWQALERVGLKEFVESLPggldtvveeggENLSVGQRQLLCLARALL 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKqGSTIIMITH--------DREigeaaarqIVIRDGNIVQ 220
Cdd:cd03244  156 RKSKILVLDEATASVDPETDALIQKTIREAFK-DCTVLTIAHrldtiidsDRI--------LVLDKGRVVE 217
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
15-199 2.43e-15

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 74.37  E-value: 2.43e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    15 AESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNiigCLDKPTTGTYELAGQNISNMTETELARVRNkeIGFVFQNFML 94
Cdd:TIGR00956  773 KEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLN---VLAERVTTGVITGGDRLVNGRPLDSSFQRS--IGYVQQQDLH 847
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    95 LPRLTalqnVELPLIYAG-------VDKKERR---ERSLAALTKVGLADRATHLPNE-LSGGQKQRVAVARAIVNNPKFI 163
Cdd:TIGR00956  848 LPTST----VRESLRFSAylrqpksVSKSEKMeyvEEVIKLLEMESYADAVVGVPGEgLNVEQRKRLTIGVELVAKPKLL 923
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 446531759   164 L-ADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:TIGR00956  924 LfLDEPTSGLDSQTAWSICKLMRKLADHGQAILCTIH 960
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
4-201 2.79e-15

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 73.82  E-value: 2.79e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    4 LKGITKSFQNGAEsvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGtyelagqnisnmtetELARVRNK 83
Cdd:TIGR03719   7 MNRVSKVVPPKKE---ILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNG---------------EARPQPGI 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   84 EIGFVFQNFMLLPRLTALQNVELPL------------IYAG-----------VDKKERRERSLAAL------TKVGLADR 134
Cdd:TIGR03719  69 KVGYLPQEPQLDPTKTVRENVEEGVaeikdaldrfneISAKyaepdadfdklAAEQAELQEIIDAAdawdldSQLEIAMD 148
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759  135 ATHLP------NELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTstqIMDLFYELNKQGSTIIMITHDR 201
Cdd:TIGR03719 149 ALRCPpwdadvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAES---VAWLERHLQEYPGTVVAVTHDR 218
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
20-199 1.41e-14

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 72.06  E-value: 1.41e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTEtelaRVRNKEIGFVFQNFMLLPRlT 99
Cdd:PRK10790 356 VLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSH----SVLRQGVAMVQQDPVVLAD-T 430
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQNVELpliyaGVDKKErrERSLAALTKVGLADRATHLP-----------NELSGGQKQRVAVARAIVNNPKFILADEP 168
Cdd:PRK10790 431 FLANVTL-----GRDISE--EQVWQALETVQLAELARSLPdglytplgeqgNNLSVGQKQLLALARVLVQTPQILILDEA 503
                        170       180       190
                 ....*....|....*....|....*....|.
gi 446531759 169 TGALDTKTSTQIMDLFYELNKQgSTIIMITH 199
Cdd:PRK10790 504 TANIDSGTEQAIQQALAAVREH-TTLVVIAH 533
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
21-219 2.59e-14

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 71.21  E-value: 2.59e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTeteLARVRNKEIGFVFQNFM---LLPR 97
Cdd:COG3845  274 LKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLS---PRERRRLGVAYIPEDRLgrgLVPD 350
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTALQNVELPLIYAG-------VDKKERRERSLAALTKVGLADRATHLP-NELSGGQKQRVAVARAIVNNPKFILADEPT 169
Cdd:COG3845  351 MSVAENLILGRYRRPpfsrggfLDRKAIRAFAEELIEEFDVRTPGPDTPaRSLSGGNQQKVILARELSRDPKLLIAAQPT 430
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446531759 170 GALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:COG3845  431 RGLDVGAIEFIHQRLLELRDAGAAVLLISEDlDEILALSDRIAVMYEGRIV 481
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
21-200 3.91e-14

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 69.32  E-value: 3.91e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTlNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAG---QNISNMTETEL----ARVRNKEIGFVF--QN 91
Cdd:cd03236   17 LHRLPVP-REGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPdwdEILDEFRGSELqnyfTKLLEGDVKVIVkpQY 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  92 FMLLPRlTALQNVELPLiyAGVDKKERRERSLAALTKVGLADRAThlpNELSGGQKQRVAVARAIVNNPKFILADEPTGA 171
Cdd:cd03236   96 VDLIPK-AVKGKVGELL--KKKDERGKLDELVDQLELRHVLDRNI---DQLSGGELQRVAIAAALARDADFYFFDEPSSY 169
                        170       180
                 ....*....|....*....|....*....
gi 446531759 172 LDTKTSTQIMDLFYELNKQGSTIIMITHD 200
Cdd:cd03236  170 LDIKQRLNAARLIRELAEDDNYVLVVEHD 198
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
24-220 4.98e-14

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 70.20  E-value: 4.98e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  24 IDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmTETELARVRN---------KEIGFvFQNFML 94
Cdd:PRK09700 282 ISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDIS--PRSPLDAVKKgmayitesrRDNGF-FPNFSI 358
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  95 LPRLTALQNVELPLiYAGV-----DKKERR----ERSLAALTKVGLADRAThlpnELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:PRK09700 359 AQNMAISRSLKDGG-YKGAmglfhEVDEQRtaenQRELLALKCHSVNQNIT----ELSGGNQQKVLISKWLCCCPEVIIF 433
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 166 DEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIVQ 220
Cdd:PRK09700 434 DEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSElPEIITVCDRIAVFCEGRLTQ 489
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
16-199 9.29e-14

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 69.67  E-value: 9.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   16 ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGtyELAGQNISNMTETELARVRNKeIGFVFQNFML- 94
Cdd:PTZ00265  396 KDVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEG--DIIINDSHNLKDINLKWWRSK-IGVVSQDPLLf 472
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   95 --------------LPRLTALQNVELPLIYAGVDKKERRERSLAALT--------------------------------- 127
Cdd:PTZ00265  473 snsiknnikyslysLKDLEALSNYYNEDGNDSQENKNKRNSCRAKCAgdlndmsnttdsneliemrknyqtikdsevvdv 552
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  128 --KVGLADRATHLPNE-----------LSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTI 194
Cdd:PTZ00265  553 skKVLIHDFVSALPDKyetlvgsnaskLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRI 632

                  ....*.
gi 446531759  195 -IMITH 199
Cdd:PTZ00265  633 tIIIAH 638
hmuV PRK13547
heme ABC transporter ATP-binding protein;
20-221 1.50e-13

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 67.93  E-value: 1.50e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNII-GCLDKP-------TTGTYELAGQNISNMTETELARVR-----NKEIG 86
Cdd:PRK13547  16 ILRDLSLRIEPGRVTALLGRNGAGKSTLLKALaGDLTGGgaprgarVTGDVTLNGEPLAAIDAPRLARLRavlpqAAQPA 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  87 FVF--QNFMLLPRLTALQNvelpliyAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVN------ 158
Cdd:PRK13547  96 FAFsaREIVLLGRYPHARR-------AGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLAQlwpphd 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 159 ---NPKFILADEPTGALDTKTSTQIMDLFYELNKQGST-IIMITHDREIGEAAARQIV-IRDGNIVQD 221
Cdd:PRK13547 169 aaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLgVLAIVHDPNLAARHADRIAmLADGAIVAH 236
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
20-173 2.15e-13

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 66.41  E-value: 2.15e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTetelarvRNKEIGFVFQNFMLLPRLT 99
Cdd:PRK13543  26 VFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGD-------RSRFMAYLGHLPGLKADLS 98
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446531759 100 ALQNVELpliYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALD 173
Cdd:PRK13543  99 TLENLHF---LCGLHGRRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLD 169
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
21-211 6.64e-13

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 64.27  E-value: 6.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGcldkpttgtyelagqnisnmtETELARVRNKeigfvfqnfmLLPRlta 100
Cdd:cd03238   11 LQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGL---------------------YASGKARLIS----------FLPK--- 56
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 101 lqNVELPLIYAGvdkkerrerSLAALTKVGLadraTHLP-----NELSGGQKQRVAVARAIVNNPK---FILaDEPTGAL 172
Cdd:cd03238   57 --FSRNKLIFID---------QLQFLIDVGL----GYLTlgqklSTLSGGELQRVKLASELFSEPPgtlFIL-DEPSTGL 120
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 446531759 173 DTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQI 211
Cdd:cd03238  121 HQQDINQLLEVIKGLIDLGNTVILIEHNLDVLSSADWII 159
ycf16 CHL00131
sulfate ABC transporter protein; Validated
17-199 8.76e-13

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 65.43  E-value: 8.76e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  17 SVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGclDKP----TTGTYELAGQNISNMTETELARvrnKEIGFVFQNF 92
Cdd:CHL00131  19 ENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIA--GHPaykiLEGDILFKGESILDLEPEERAH---LGIFLAFQYP 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  93 MLLPRLTalqNVE-LPLIYAGVDKKERR---------ERSLAALTKVGLADRATHLP-NE-LSGGQKQRVAVARAIVNNP 160
Cdd:CHL00131  94 IEIPGVS---NADfLRLAYNSKRKFQGLpeldpleflEIINEKLKLVGMDPSFLSRNvNEgFSGGEKKRNEILQMALLDS 170
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:CHL00131 171 ELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITH 209
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
19-199 1.04e-12

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 64.19  E-value: 1.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGclDKPTTGTYE----LAGQNIsnmtETELARvrnkEIGFVFQNFML 94
Cdd:cd03232   21 QLLNNISGYVKPGTLTALMGESGAGKTTLLDVLA--GRKTAGVITgeilINGRPL----DKNFQR----STGYVEQQDVH 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  95 LPRLTalqnVELPLIYAgvdkkerrerslAALtkvgladrathlpNELSGGQKQRVAVARAIVNNPKFILADEPTGALDT 174
Cdd:cd03232   91 SPNLT----VREALRFS------------ALL-------------RGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDS 141
                        170       180
                 ....*....|....*....|....*
gi 446531759 175 KTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:cd03232  142 QAAYNIVRFLKKLADSGQAILCTIH 166
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
4-180 1.42e-12

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 66.29  E-value: 1.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759     4 LKGITKSFQNGAES--VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGC------LDKPTTGTYELAGQNisnmtet 75
Cdd:TIGR00956   58 LTRGFRKLKKFRDTktFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASntdgfhIGVEGVITYDGITPE------- 130
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    76 ELARVRNKEIGFVFQNFMLLPRLTALQNVELP-------LIYAGVDKKERRERSLA-ALTKVGLAD-RATHLPNEL---- 142
Cdd:TIGR00956  131 EIKKHYRGDVVYNAETDVHFPHLTVGETLDFAarcktpqNRPDGVSREEYAKHIADvYMATYGLSHtRNTKVGNDFvrgv 210
                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 446531759   143 SGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQI 180
Cdd:TIGR00956  211 SGGERKRVSIAEASLGGAKIQCWDNATRGLDSATALEF 248
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
26-213 1.62e-12

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 66.19  E-value: 1.62e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    26 VTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNI-SNMTEtelarvrnkeigfVFQNFMLLPRLTALQNV 104
Cdd:TIGR01257 1960 VGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIlTNISD-------------VHQNMGYCPQFDAIDDL 2026
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   105 ----ELPLIYA---GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTS 177
Cdd:TIGR01257 2027 ltgrEHLYLYArlrGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQAR 2106
                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 446531759   178 TQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVI 213
Cdd:TIGR01257 2107 RMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAI 2142
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
20-201 2.22e-12

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 63.43  E-value: 2.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmtETELARVRnKEIGFVFQNFMLLPRLT 99
Cdd:PRK13540  16 LLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI----KKDLCTYQ-KQLCFVGHRSGINPYLT 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQNVELPLIYA----GVDKkerrersLAALTKVG-LADRATHLpneLSGGQKQRVAVARAIVNNPKFILADEPTGALDT 174
Cdd:PRK13540  91 LRENCLYDIHFSpgavGITE-------LCRLFSLEhLIDYPCGL---LSSGQKRQVALLRLWMSKAKLWLLDEPLVALDE 160
                        170       180
                 ....*....|....*....|....*..
gi 446531759 175 KTSTQIMDLFYELNKQGSTIIMITHDR 201
Cdd:PRK13540 161 LSLLTIITKIQEHRAKGGAVLLTSHQD 187
PLN03140 PLN03140
ABC transporter G family member; Provisional
18-203 3.75e-12

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 65.25  E-value: 3.75e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   18 VQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIigcLDKPTTGTYELAGQNISNMTETE--LARVRnkeiGFVFQNFMLL 95
Cdd:PLN03140  893 LQLLREVTGAFRPGVLTALMGVSGAGKTTLMDV---LAGRKTGGYIEGDIRISGFPKKQetFARIS----GYCEQNDIHS 965
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   96 PRLTalqnVELPLIYAG-------VDKKERR---ERSLAALTKVGLADRATHLP--NELSGGQKQRVAVARAIVNNPKFI 163
Cdd:PLN03140  966 PQVT----VRESLIYSAflrlpkeVSKEEKMmfvDEVMELVELDNLKDAIVGLPgvTGLSTEQRKRLTIAVELVANPSII 1041
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 446531759  164 LADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREI 203
Cdd:PLN03140 1042 FMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSI 1081
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
25-224 5.75e-12

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 64.20  E-value: 5.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  25 DVTLNQGEFTSIMGPSGSGKSTLMNIIG---CLD--------------------KPTTGTY---------ELAGQ----- 67
Cdd:PRK11147  23 ELHIEDNERVCLVGRNGAGKSTLMKILNgevLLDdgriiyeqdlivarlqqdppRNVEGTVydfvaegieEQAEYlkryh 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  68 NISNMTETElarvrnkeigfvfQNFMLLPRLTALQNVelpLIYAGVDKKERRERSLaaLTKVGLaDRATHLpNELSGGQK 147
Cdd:PRK11147 103 DISHLVETD-------------PSEKNLNELAKLQEQ---LDHHNLWQLENRINEV--LAQLGL-DPDAAL-SSLSGGWL 162
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 148 QRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFyeLNKQGStIIMITHDREIGEAAARQIVIRDGNIVQDWRG 224
Cdd:PRK11147 163 RKAALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFL--KTFQGS-IIFISHDRSFIRNMATRIVDLDRGKLVSYPG 236
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
30-199 7.17e-12

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 63.99  E-value: 7.17e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  30 QGEFTSIMGPSGSGKSTLMNII-GCLDkPTTGTYELAGQNI--SNMtETelaRVRnkeIGFVFQNFMLLPRLTALQNVEL 106
Cdd:NF033858 291 RGEIFGFLGSNGCGKSTTMKMLtGLLP-ASEGEAWLFGQPVdaGDI-AT---RRR---VGYMSQAFSLYGELTVRQNLEL 362
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 107 pliYA---GVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDtktsTQIMDL 183
Cdd:NF033858 363 ---HArlfHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD----PVARDM 435
                        170       180
                 ....*....|....*....|.
gi 446531759 184 FYEL-----NKQGSTIIMITH 199
Cdd:NF033858 436 FWRLlielsREDGVTIFISTH 456
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
2-218 8.09e-12

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 63.84  E-value: 8.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVQilhGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmTETELARVR 81
Cdd:PRK10522 323 LELRNVTFAYQDNGFSVG---PINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPV---TAEQPEDYR 396
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQNFMLLPRLTALQNVELPliyagvdkKERRERSLAAL---TKVGLAD-RATHLpnELSGGQKQRVAVARAIV 157
Cdd:PRK10522 397 -KLFSAVFTDFHLFDQLLGPEGKPAN--------PALVEKWLERLkmaHKLELEDgRISNL--KLSKGQKKRLALLLALA 465
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 158 NNPKFILADEPTGALDtktsTQIMDLFY-----ELNKQGSTIIMITHDREIGEAAARQIVIRDGNI 218
Cdd:PRK10522 466 EERDILLLDEWAADQD----PHFRREFYqvllpLLQEMGKTIFAISHDDHYFIHADRLLEMRNGQL 527
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
21-200 1.20e-11

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 62.53  E-value: 1.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYElagqnisnmtetelarvRNKEIGFVFQNFMLLPRLTA 100
Cdd:PRK13546  40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVD-----------------RNGEVSVIAISAGLSGQLTG 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 101 LQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQI 180
Cdd:PRK13546 103 IENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKC 182
                        170       180
                 ....*....|....*....|
gi 446531759 181 MDLFYELNKQGSTIIMITHD 200
Cdd:PRK13546 183 LDKIYEFKEQNKTIFFVSHN 202
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
21-218 1.46e-11

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 63.10  E-value: 1.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNII-GCLDKpTTGTYELAGQNISNMTETE-LA---------RVRNkeiGFVF 89
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLyGALPR-TSGYVTLDGHEVVTRSPQDgLAngivyisedRKRD---GLVL 343
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  90 -----QNFmllpRLTALQNvelpLIYAGVDKKERRERsLAALTKVGLADRAThlPN------ELSGGQKQRVAVARAIVN 158
Cdd:PRK10762 344 gmsvkENM----SLTALRY----FSRAGGSLKHADEQ-QAVSDFIRLFNIKT--PSmeqaigLLSGGNQQKVAIARGLMT 412
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 159 NPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDR-EIGEAAARQIVIRDGNI 218
Cdd:PRK10762 413 RPKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMpEVLGMSDRILVMHEGRI 473
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
2-221 1.47e-11

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 62.89  E-value: 1.47e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVQ-ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIsnmTETELARV 80
Cdd:COG4615  328 LELRGVTYRYPGEDGDEGfTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPV---TADNREAY 404
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKeigF--VFQNFMLLPRLTALQNVELPliyagvdkkERRERSLAAL---TKVGLADRA--ThlpNELSGGQKQRVAVA 153
Cdd:COG4615  405 RQL---FsaVFSDFHLFDRLLGLDGEADP---------ARARELLERLeldHKVSVEDGRfsT---TDLSQGQRKRLALL 469
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 154 RAIVNNPKFILADE------PtgaldtktstQIMDLFY-----ELNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:COG4615  470 VALLEDRPILVFDEwaadqdP----------EFRRVFYtellpELKARGKTVIAISHDDRYFDLADRVLKMDYGKLVEL 538
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
24-219 2.21e-11

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 62.62  E-value: 2.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  24 IDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISnmteteLARVRNKeigfVFQNFMLLPR------ 97
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPID------IRSPRDA----IRAGIMLCPEdrkaeg 341
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTALQNVELPL--------IYAGVDKKERRERSLA----ALTKVGLADRATHLPNeLSGGQKQRVAVARAIVNNPKFILA 165
Cdd:PRK11288 342 IIPVHSVADNInisarrhhLRAGCLINNRWEAENAdrfiRSLNIKTPSREQLIMN-LSGGNQQKAILGRWLSEDMKVILL 420
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 166 DEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIV 219
Cdd:PRK11288 421 DEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDlPEVLGVADRIVVMREGRIA 475
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
20-173 2.58e-11

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 62.34  E-value: 2.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIgcldkptTGTYElagQNISNMTeTELARVR---------NKEIGFVFQ 90
Cdd:PRK10938 275 ILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLI-------TGDHP---QGYSNDL-TLFGRRRgsgetiwdiKKHIGYVSS 343
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  91 NFMLLPRL-TALQNVELP------LIYAGVDKkerRERSLAA--LTKVGLADRATHLP-NELSGGQKQRVAVARAIVNNP 160
Cdd:PRK10938 344 SLHLDYRVsTSVRNVILSgffdsiGIYQAVSD---RQQKLAQqwLDILGIDKRTADAPfHSLSWGQQRLALIVRALVKHP 420
                        170
                 ....*....|...
gi 446531759 161 KFILADEPTGALD 173
Cdd:PRK10938 421 TLLILDEPLQGLD 433
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
9-220 2.94e-11

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 62.04  E-value: 2.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   9 KSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELaRVRNKEIG-- 86
Cdd:PRK10789 319 RQFTYPQTDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSW-RSRLAVVSqt 397
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  87 -FVFQNfmllprlTALQNVELPLIYAGVDKKERRERsLAAL------------TKVGlaDRATHLpnelSGGQKQRVAVA 153
Cdd:PRK10789 398 pFLFSD-------TVANNIALGRPDATQQEIEHVAR-LASVhddilrlpqgydTEVG--ERGVML----SGGQKQRISIA 463
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMDLFYELnKQGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:PRK10789 464 RALLLNAEILILDDALSAVDGRTEHQILHNLRQW-GEGRTVIISAHRLSALTEASEILVMQHGHIAQ 529
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
7-216 3.92e-11

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 60.42  E-value: 3.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   7 ITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLM-NIIGCLDKPTTGTYELAGQNISNMTETELARVRNkEI 85
Cdd:cd03290    3 VTNGYFSWGSGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLlAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRY-SV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  86 GFVFQNFMLLPrltalQNVELPLIYAGVDKKERRERSLAALT------------KVGLADRATHLpnelSGGQKQRVAVA 153
Cdd:cd03290   82 AYAAQKPWLLN-----ATVEENITFGSPFNKQRYKAVTDACSlqpdidllpfgdQTEIGERGINL----SGGQRQRICVA 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446531759 154 RAIVNNPKFILADEPTGALDTKTSTQIMD--LFYELNKQGSTIIMITHDREIGEAAARQIVIRDG 216
Cdd:cd03290  153 RALYQNTNIVFLDDPFSALDIHLSDHLMQegILKFLQDDKRTLVLVTHKLQYLPHADWIIAMKDG 217
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
4-201 5.16e-11

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 61.29  E-value: 5.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGAEsvqilhgIDVtlnqgeftsiMGPSGSGKSTLMNIIGCLDKPTTGTYELAgQNISnmtetelarvrnk 83
Cdd:PRK11819  23 LKDISLSFFPGAK-------IGV----------LGLNGAGKSTLLRIMAGVDKEFEGEARPA-PGIK------------- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 eIGFVFQNFMLLPRLTALQNVELPL------------IYAG-----------VDKKERRERSLAAL------TKVGLADR 134
Cdd:PRK11819  72 -VGYLPQEPQLDPEKTVRENVEEGVaevkaaldrfneIYAAyaepdadfdalAAEQGELQEIIDAAdawdldSQLEIAMD 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 135 ATHLP------NELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKtSTQIMDLFyeLNKQGSTIIMITHDR 201
Cdd:PRK11819 151 ALRCPpwdakvTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAE-SVAWLEQF--LHDYPGTVVAVTHDR 220
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
21-218 1.97e-10

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 59.96  E-value: 1.97e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCLDKpTTGTYELAG-----------QNISnMTETEL--ARVRNKEIG 86
Cdd:TIGR00957  654 LNGITFSIPEGALVAVVGQVGCGKSSLLSaLLAEMDK-VEGHVHMKGsvayvpqqawiQNDS-LRENILfgKALNEKYYQ 731
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    87 FVFQNFMLLPRLTALqnvelpliyAGVDKKERRERSLaaltkvgladrathlpnELSGGQKQRVAVARAIVNNPKFILAD 166
Cdd:TIGR00957  732 QVLEACALLPDLEIL---------PSGDRTEIGEKGV-----------------NLSGGQKQRVSLARAVYSNADIYLFD 785
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 446531759   167 EPTGALDTKTSTQIMD--LFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNI 218
Cdd:TIGR00957  786 DPLSAVDAHVGKHIFEhvIGPEGVLKNKTRILVTHGISYLPQVDVIIVMSGGKI 839
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
142-220 2.36e-10

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 59.66  E-value: 2.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  142 LSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITHdREIGEAAARQIVI-----RD 215
Cdd:PTZ00265 1359 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIkDKADKTIITIAH-RIASIKRSDKIVVfnnpdRT 1437

                  ....*
gi 446531759  216 GNIVQ 220
Cdd:PTZ00265 1438 GSFVQ 1442
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
113-221 2.57e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 58.98  E-value: 2.57e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 113 VDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGS 192
Cdd:NF000106 116 LSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGA 195
                         90       100       110
                 ....*....|....*....|....*....|
gi 446531759 193 TIIMITHDREIGEAAARQIVIRD-GNIVQD 221
Cdd:NF000106 196 TVLLTTQYMEEAEQLAHELTVIDrGRVIAD 225
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
21-199 5.10e-10

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 58.36  E-value: 5.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGqnisnmTETELArvrnkeIGFVFQNfmllpRLTA 100
Cdd:PRK13545  40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG------SAALIA------ISSGLNG-----QLTG 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 101 LQNVELPLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQI 180
Cdd:PRK13545 103 IENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKC 182
                        170
                 ....*....|....*....
gi 446531759 181 MDLFYELNKQGSTIIMITH 199
Cdd:PRK13545 183 LDKMNEFKEQGKTIFFISH 201
PLN03232 PLN03232
ABC transporter C family member; Provisional
21-221 1.47e-09

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 57.29  E-value: 1.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCLDKPTTGTYELAGQ--NISNMTETELARVR-NKEIGFVFQN--FML 94
Cdd:PLN03232  633 LSDINLEIPVGSLVAIVGGTGEGKTSLISaMLGELSHAETSSVVIRGSvaYVPQVSWIFNATVReNILFGSDFESerYWR 712
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   95 LPRLTALQNvELPLiYAGVDKKERRERSLaaltkvgladrathlpnELSGGQKQRVAVARAIVNNPKFILADEPTGALDT 174
Cdd:PLN03232  713 AIDVTALQH-DLDL-LPGRDLTEIGERGV-----------------NISGGQKQRVSMARAVYSNSDIYIFDDPLSALDA 773
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 446531759  175 KTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:PLN03232  774 HVAHQVFDSCMKDELKGKTRVLVTNQLHFLPLMDRIILVSEGMIKEE 820
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
1-201 1.66e-09

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 56.82  E-value: 1.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   1 MINLKGITKSFqnGAESvqILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGtyelagqNISNMTETELARV 80
Cdd:PRK15064   1 MLSTANITMQF--GAKP--LFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAG-------NVSLDPNERLGKL 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  81 RNKEigFVFQNFMLLP-----------------RLTALQNV---------ELPLIYAGVDKKERRERSLAALTKVGLA-D 133
Cdd:PRK15064  70 RQDQ--FAFEEFTVLDtvimghtelwevkqerdRIYALPEMseedgmkvaDLEVKFAEMDGYTAEARAGELLLGVGIPeE 147
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 134 RATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTstqIMDLFYELNKQGSTIIMITHDR 201
Cdd:PRK15064 148 QHYGLMSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDINT---IRWLEDVLNERNSTMIIISHDR 212
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
4-216 2.87e-09

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 56.28  E-value: 2.87e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETElarVRNK 83
Cdd:PRK10982   1 MSNISKSF----PGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKE---ALEN 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  84 EIGFVFQNFMLLPRLTALQNVEL---PLIYAGVDKKERRERSLAALTKVGLADRATHLPNELSGGQKQRVAVARAIVNNP 160
Cdd:PRK10982  74 GISMVHQELNLVLQRSVMDNMWLgryPTKGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNA 153
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDG 216
Cdd:PRK10982 154 KIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKmEEIFQLCDEITILRDG 210
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
21-207 3.16e-09

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 54.96  E-value: 3.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLM---------------------NIIGCLDKPTTGTYELAGQNISnmtetelar 79
Cdd:cd03270   11 LKNVDVDIPRNKLVVITGVSGSGKSSLAfdtiyaegqrryveslsayarQFLGQMDKPDVDSIEGLSPAIA--------- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRNKEIGfvfQNfmllPRLTALQNVE----LPLIYAGVDKKERrersLAALTKVGLA----DRAThlpNELSGGQKQRVA 151
Cdd:cd03270   82 IDQKTTS---RN----PRSTVGTVTEiydyLRLLFARVGIRER----LGFLVDVGLGyltlSRSA---PTLSGGEAQRIR 147
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759 152 VARAIVNNPK---FILaDEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAA 207
Cdd:cd03270  148 LATQIGSGLTgvlYVL-DEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVEHDEDTIRAA 205
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
33-217 3.72e-09

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 54.54  E-value: 3.72e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  33 FTSIMGPSGSGKSTlmnIIGCLDKPTTGtyELAGQNISNMTETELARVrNKEIGFVFQNFmllprltalqnvelpliYAG 112
Cdd:cd03240   24 LTLIVGQNGAGKTT---IIEALKYALTG--ELPPNSKGGAHDPKLIRE-GEVRAQVKLAF-----------------ENA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 113 VDKKERRERSLAALTKV------GLADRATHLPNELSGGQKQ------RVAVARAIVNNPKFILADEPTGALDT-KTSTQ 179
Cdd:cd03240   81 NGKKYTITRSLAILENVifchqgESNWPLLDMRGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEeNIEES 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 446531759 180 IMDLFYELNKQG-STIIMITHDREIGEAAARQI-VIRDGN 217
Cdd:cd03240  161 LAEIIEERKSQKnFQLIVITHDEELVDAADHIYrVEKDGR 200
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
7-219 3.89e-09

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 54.58  E-value: 3.89e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   7 ITKSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGcldkPTTGTYELAGQNIS--NMTETELARVRNKE 84
Cdd:cd03233    9 ISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALA----NRTEGNVSVEGDIHynGIPYKEFAEKYPGE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  85 IGFVFQNFMLLPRLTALQNVELPLIYAGvdkkerrerslaaltkvgladrathlpNE----LSGGQKQRVAVARAIVNNP 160
Cdd:cd03233   85 IIYVSEEDVHFPTLTVRETLDFALRCKG---------------------------NEfvrgISGGERKRVSIAEALVSRA 137
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 161 KFILADEPTGALDTKTSTQIMDLFYEL-NKQGSTIIMITH--DREIGEAAARQIVIRDGNIV 219
Cdd:cd03233  138 SVLCWDNSTRGLDSSTALEILKCIRTMaDVLKTTTFVSLYqaSDEIYDLFDKVLVLYEGRQI 199
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
30-200 4.38e-09

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 55.95  E-value: 4.38e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  30 QGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYE-----------LAGqnisnmteTEL----ARVRNKEIGFVFQNfml 94
Cdd:COG1245   98 KGKVTGILGPNGIGKSTALKILSGELKPNLGDYDeepswdevlkrFRG--------TELqdyfKKLANGEIKVAHKP--- 166
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  95 lprltalQNVEL-PLIYAGV-----DKKERRERSLAALTKVGLA---DRAThlpNELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:COG1245  167 -------QYVDLiPKVFKGTvrellEKVDERGKLDELAEKLGLEnilDRDI---SELSGGELQRVAIAAALLRDADFYFF 236
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 446531759 166 DEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD 200
Cdd:COG1245  237 DEPSSYLDIYQRLNVARLIRELAEEGKYVLVVEHD 271
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
24-218 4.67e-09

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 55.83  E-value: 4.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  24 IDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNM-TETELARvrnkeiGFVFqnfmlLP--RLTA 100
Cdd:PRK15439 282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALsTAQRLAR------GLVY-----LPedRQSS 350
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 101 LQNVELPLIYAGVD------------KKERR--ERSLAAL-TKVGLADRAThlpNELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:PRK15439 351 GLYLDAPLAWNVCAlthnrrgfwikpARENAvlERYRRALnIKFNHAEQAA---RTLSGGNQQKVLIAKCLEASPQLLIV 427
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446531759 166 DEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNI 218
Cdd:PRK15439 428 DEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDlEEIEQMADRVLVMHQGEI 481
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
20-182 6.80e-09

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 54.48  E-value: 6.80e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTL-MNIIGCLDkPTTGTYELAGQnisnmtetelarvrnkeIGFVFQNFMLLPRl 98
Cdd:cd03291   52 VLKNINLKIEKGEMLAITGSTGSGKTSLlMLILGELE-PSEGKIKHSGR-----------------ISFSSQFSWIMPG- 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  99 TALQNvelplIYAGVDKKERRERSLAALTKvgLADRATHLPNE-----------LSGGQKQRVAVARAIVNNPKFILADE 167
Cdd:cd03291  113 TIKEN-----IIFGVSYDEYRYKSVVKACQ--LEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDS 185
                        170
                 ....*....|....*
gi 446531759 168 PTGALDTKTSTQIMD 182
Cdd:cd03291  186 PFGYLDVFTEKEIFE 200
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
17-169 7.59e-09

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 55.13  E-value: 7.59e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  17 SVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNmtetelARVRNK---EIGFVFQ--- 90
Cdd:NF033858  13 KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMAD------ARHRRAvcpRIAYMPQglg 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  91 -NfmLLPRLTALQNVELpliYA---GVDKKERRERsLAALTK-VGLADRATHLPNELSGGQKQRVAVARAIVNNPKFILA 165
Cdd:NF033858  87 kN--LYPTLSVFENLDF---FGrlfGQDAAERRRR-IDELLRaTGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLIL 160

                 ....
gi 446531759 166 DEPT 169
Cdd:NF033858 161 DEPT 164
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
23-214 9.88e-09

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 52.75  E-value: 9.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  23 GIDVTLNQGEFTSIMGPSGSGKSTLMNIIGcldkpttgtyelagqnisnmtetelarvrnkeIGFVFQNFMLLPRLTALQ 102
Cdd:cd03227   13 PNDVTFGEGSLTIITGPNGSGKSTILDAIG--------------------------------LALGGAQSATRRRSGVKA 60
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 103 NVELPLIYAGvdkkerrerslAALTKVGLadrathlpnelSGGQKQRVAVARAI----VNNPKFILADEPTGALDTKTST 178
Cdd:cd03227   61 GCIVAAVSAE-----------LIFTRLQL-----------SGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQ 118
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 446531759 179 QIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIR 214
Cdd:cd03227  119 ALAEAILEHLVKGAQVIVITHLPELAELADKLIHIK 154
PTZ00243 PTZ00243
ABC transporter; Provisional
16-219 1.25e-08

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 54.78  E-value: 1.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   16 ESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNiigcldkpttgtyelagqniSNMTETELARVR---NKEIGFVFQNF 92
Cdd:PTZ00243  671 EPKVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQ--------------------SLLSQFEISEGRvwaERSIAYVPQQA 730
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   93 MLLpRLTALQNVelpLIYagvdkKERRERSLAALTKVG-----LADRATHLPNE-------LSGGQKQRVAVARAIVNNP 160
Cdd:PTZ00243  731 WIM-NATVRGNI---LFF-----DEEDAARLADAVRVSqleadLAQLGGGLETEigekgvnLSGGQKARVSLARAVYANR 801
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759  161 KFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIV 219
Cdd:PTZ00243  802 DVYLLDDPLSALDAHVGERVVEECFLGALAGKTRVLATHQVHVVPRADYVVALGDGRVE 860
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
20-182 3.08e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 53.38  E-value: 3.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    20 ILHGIDVTLNQGEFTSIMGPSGSGKSTL-MNIIGCLDkPTTGTYELAGQnisnmtetelarvrnkeIGFVFQNFMLLPRl 98
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLlMMIMGELE-PSEGKIKHSGR-----------------ISFSPQTSWIMPG- 501
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    99 TALQNvelplIYAGVDKKERRERSLaaLTKVGLADRATHLPNE-----------LSGGQKQRVAVARAIVNNPKFILADE 167
Cdd:TIGR01271  502 TIKDN-----IIFGLSYDEYRYTSV--IKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLDS 574
                          170
                   ....*....|....*
gi 446531759   168 PTGALDTKTSTQIMD 182
Cdd:TIGR01271  575 PFTHLDVVTEKEIFE 589
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
27-200 4.75e-08

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 52.50  E-value: 4.75e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  27 TLNQGEFTSIMGPSGSGKSTLMNIigcldkpttgtyeLAGQNISNMTE----------------TEL----ARVRNKEIG 86
Cdd:PRK13409  95 IPKEGKVTGILGPNGIGKTTAVKI-------------LSGELIPNLGDyeeepswdevlkrfrgTELqnyfKKLYNGEIK 161
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  87 FVFQNfmllprltalQNVEL-PLIYAG--------VDKKERRERSLAALTKVGLADRAThlpNELSGGQKQRVAVARAIV 157
Cdd:PRK13409 162 VVHKP----------QYVDLiPKVFKGkvrellkkVDERGKLDEVVERLGLENILDRDI---SELSGGELQRVAIAAALL 228
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 446531759 158 NNPKFILADEPTGALDTKTSTQIMDLFYELNKqGSTIIMITHD 200
Cdd:PRK13409 229 RDADFYFFDEPTSYLDIRQRLNVARLIRELAE-GKYVLVVEHD 270
PLN03073 PLN03073
ABC transporter F family; Provisional
35-218 5.36e-08

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 52.55  E-value: 5.36e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  35 SIMGPSGSGKSTLMNIIGCLDKPTTGTYELAgqnisnmtetelARVRNKeigfVFQNFmllpRLTALQNVELPLIY---- 110
Cdd:PLN03073 539 AMVGPNGIGKSTILKLISGELQPSSGTVFRS------------AKVRMA----VFSQH----HVDGLDLSSNPLLYmmrc 598
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 111 -AGVDKKERRerslAALTKVGLADRATHLP-NELSGGQKQRVAVARAIVNNPKFILADEPTGALD---TKTSTQIMDLFy 185
Cdd:PLN03073 599 fPGVPEQKLR----AHLGSFGVTGNLALQPmYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDldaVEALIQGLVLF- 673
                        170       180       190
                 ....*....|....*....|....*....|....
gi 446531759 186 elnkQGStIIMITHDREIGEAAARQI-VIRDGNI 218
Cdd:PLN03073 674 ----QGG-VLMVSHDEHLISGSVDELwVVSEGKV 702
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
2-201 6.72e-08

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 52.24  E-value: 6.72e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    2 INLKGITKSFqngaESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAgqnisnmtETelarVR 81
Cdd:TIGR03719 323 IEAENLTKAF----GDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIG--------ET----VK 386
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   82 nkeIGFVFQNFMLL-PRLTALQNVELPLIYAGVDKKERRERSLAAL---------TKVGladrathlpnELSGGQKQRVA 151
Cdd:TIGR03719 387 ---LAYVDQSRDALdPNKTVWEEISGGLDIIKLGKREIPSRAYVGRfnfkgsdqqKKVG----------QLSGGERNRVH 453
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 446531759  152 VARAIVNNPKFILADEPTGALDTKTSTQIMDLFyeLNKQGSTIImITHDR 201
Cdd:TIGR03719 454 LAKTLKSGGNVLLLDEPTNDLDVETLRALEEAL--LNFAGCAVV-ISHDR 500
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
9-203 1.18e-07

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 50.95  E-value: 1.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   9 KSFQNGAESVQILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLD--KPTTGTYELAGQNISNMTETE-------LAR 79
Cdd:PRK09580   5 KDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSPEDragegifMAF 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  80 VRNKEIGFVFQNFMLLPRLTALQNvelpliYAGVDKKERRERSLAALTKVGL----ADRATHLPNE-LSGGQKQRVAVAR 154
Cdd:PRK09580  85 QYPVEIPGVSNQFFLQTALNAVRS------YRGQEPLDRFDFQDLMEEKIALlkmpEDLLTRSVNVgFSGGEKKRNDILQ 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446531759 155 AIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREI 203
Cdd:PRK09580 159 MAVLEPELCILDESDSGLDIDALKIVADGVNSLRDGKRSFIIVTHYQRI 207
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
27-221 1.68e-07

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 50.98  E-value: 1.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   27 TLNQGEFTSIMGPSGSGKSTLMN-IIGCLDKPTTGTYELAGQNISnmTETELARVRNKeIGFVFQNFM---LLPRLTALQ 102
Cdd:TIGR02633 282 SLRRGEILGVAGLVGAGRTELVQaLFGAYPGKFEGNVFINGKPVD--IRNPAQAIRAG-IAMVPEDRKrhgIVPILGVGK 358
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  103 NVELPLI--YAG---VDKKERRERSLAALTKVGLADRATHLP-NELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:TIGR02633 359 NITLSVLksFCFkmrIDAAAELQIIGSAIQRLKVKTASPFLPiGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGA 438
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 446531759  177 STQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNIVQD 221
Cdd:TIGR02633 439 KYEIYKLINQLAQEGVAIIVVSSElAEVLGLSDRVLVIGEGKLKGD 484
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
30-217 1.76e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 48.91  E-value: 1.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    30 QGEFTSIMGPSGSGKSTLMN-IIGCLDKPTTGTYELAGQNISNMTETELARVRNKEIGfvfqnfmllprltalqnvelpl 108
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARaLARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKK---------------------- 58
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   109 iyagvdkkerrerslaaltkvgladrathlpNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMD------ 182
Cdd:smart00382  59 -------------------------------ASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLleelrl 107
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 446531759   183 LFYELNKQGSTIIMITH------DREIGEAAARQIVIRDGN 217
Cdd:smart00382 108 LLLLKSEKNLTVILTTNdekdlgPALLRRRFDRRIVLLLIL 148
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
142-218 2.02e-07

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 50.70  E-value: 2.02e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759 142 LSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHD-REIGEAAARQIVIRDGNI 218
Cdd:PRK13549 406 LSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSElPEVLGLSDRVLVMHEGKL 483
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
19-197 2.28e-07

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 50.40  E-value: 2.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  19 QILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTETELARVRNKEigfvFQ---NFMLL 95
Cdd:PRK10938  17 KTLQLPSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEQLQKLVSDE----WQrnnTDMLS 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  96 P------RLTAlqnvelPLIYAGVDKKERRERsLAALTKVG--LADRATHLpnelSGGQKQRVAVARAIVNNPKFILADE 167
Cdd:PRK10938  93 PgeddtgRTTA------EIIQDEVKDPARCEQ-LAQQFGITalLDRRFKYL----STGETRKTLLCQALMSEPDLLILDE 161
                        170       180       190
                 ....*....|....*....|....*....|
gi 446531759 168 PTGALDTKTSTQIMDLFYELNKQGSTIIMI 197
Cdd:PRK10938 162 PFDGLDVASRQQLAELLASLHQSGITLVLV 191
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
27-200 5.06e-07

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 48.94  E-value: 5.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  27 TLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNIS----------NMTETELarVRNKEIGFVFQNFMllp 96
Cdd:cd03237   21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSykpqyikadyEGTVRDL--LSSITKDFYTHPYF--- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 rltalqNVELpliyagvdkkerrersLAALTKVGLADRAThlpNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKT 176
Cdd:cd03237   96 ------KTEI----------------AKPLQIEQILDREV---PELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQ 150
                        170       180
                 ....*....|....*....|....*..
gi 446531759 177 ---STQIMDLFYELNKqgSTIIMITHD 200
Cdd:cd03237  151 rlmASKVIRRFAENNE--KTAFVVEHD 175
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
2-220 5.14e-07

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 49.08  E-value: 5.14e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   2 INLKGITKSFQNGAESVqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKpTTGTYELAGQNISNMTeteLARVR 81
Cdd:cd03289    3 MTVKDLTAKYTEGGNAV--LENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVP---LQKWR 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 nKEIGFVFQNFMLLPRlTALQNVElPLiyagvdKKERRERSLAALTKVGLADRATHLPNEL-----------SGGQKQRV 150
Cdd:cd03289   77 -KAFGVIPQKVFIFSG-TFRKNLD-PY------GKWSDEEIWKVAEEVGLKSVIEQFPGQLdfvlvdggcvlSHGHKQLM 147
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 151 AVARAIVNNPKFILADEPTGALDTKTStQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQ 220
Cdd:cd03289  148 CLARSVLSKAKILLLDEPSAHLDPITY-QVIRKTLKQAFADCTVILSEHRIEAMLECQRFLVIEENKVRQ 216
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
36-199 8.86e-07

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 48.98  E-value: 8.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   36 IMGPSGSGKSTLMNIIGCL--------------------DKPTTGTYELAGQNISNMTETELarvrnKEIGFVFQNFMLL 95
Cdd:TIGR00954 483 ICGPNGCGKSSLFRILGELwpvyggrltkpakgklfyvpQRPYMTLGTLRDQIIYPDSSEDM-----KRRGLSDKDLEQI 557
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   96 prltaLQNVELPLIYagvdkkeRRERSLAALtkvglADRAthlpNELSGGQKQRVAVARAIVNNPKFILADEPTGALdtk 175
Cdd:TIGR00954 558 -----LDNVQLTHIL-------EREGGWSAV-----QDWM----DVLSGGEKQRIAMARLFYHKPQFAILDECTSAV--- 613
                         170       180
                  ....*....|....*....|....*
gi 446531759  176 tSTQIMDLFYELNKQ-GSTIIMITH 199
Cdd:TIGR00954 614 -SVDVEGYMYRLCREfGITLFSVSH 637
PLN03130 PLN03130
ABC transporter C family member; Provisional
21-221 9.06e-07

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 48.97  E-value: 9.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCLDKPTTGTYELAGQ--NISNMTETELARVR-NKEIGFVFQ--NFML 94
Cdd:PLN03130  633 LSNINLDVPVGSLVAIVGSTGEGKTSLISaMLGELPPRSDASVVIRGTvaYVPQVSWIFNATVRdNILFGSPFDpeRYER 712
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   95 LPRLTALQNvELPLIyAGVDKKERRERSLaaltkvgladrathlpnELSGGQKQRVAVARAIVNNPKFILADEPTGALDT 174
Cdd:PLN03130  713 AIDVTALQH-DLDLL-PGGDLTEIGERGV-----------------NISGGQKQRVSMARAVYSNSDVYIFDDPLSALDA 773
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 446531759  175 KTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQD 221
Cdd:PLN03130  774 HVGRQVFDKCIKDELRGKTRVLVTNQLHFLSQVDRIILVHEGMIKEE 820
PRK01156 PRK01156
chromosome segregation protein; Provisional
140-207 1.36e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.36  E-value: 1.36e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 140 NELSGGQKQ------RVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTI---IMITHDREIGEAA 207
Cdd:PRK01156 800 DSLSGGEKTavafalRVAVAQFLNNDKSLLIMDEPTAFLDEDRRTNLKDIIEYSLKDSSDIpqvIMISHHRELLSVA 876
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
123-216 3.35e-06

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 47.52  E-value: 3.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  123 LAALTKVGLA----DRAThlpNELSGGQKQRVAVAR---AIVNNPKFILaDEPTGALDTKTSTQIMDLFYELNKQGSTII 195
Cdd:PRK00635  457 LSILIDLGLPyltpERAL---ATLSGGEQERTALAKhlgAELIGITYIL-DEPSIGLHPQDTHKLINVIKKLRDQGNTVL 532
                          90       100
                  ....*....|....*....|.
gi 446531759  196 MITHDREIGEAAARQIVIRDG 216
Cdd:PRK00635  533 LVEHDEQMISLADRIIDIGPG 553
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
21-199 3.38e-06

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 47.32  E-value: 3.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMN-----------------------IIGC--LDK------------PTT--GT 61
Cdd:TIGR00630 624 LKNITVSIPLGLFTCITGVSGSGKSTLINdtlypalanrlngaktvpgrytsIEGLehLDKvihidqspigrtPRSnpAT 703
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   62 YELAGQNISNM-TETELARVRNKEIG-FVFQnfMLLPRLTALQ-----NVE---LPLIYAGVD----KKERRE------- 120
Cdd:TIGR00630 704 YTGVFDEIRELfAETPEAKVRGYTPGrFSFN--VKGGRCEACQgdgviKIEmhfLPDVYVPCEvckgKRYNREtlevkyk 781
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  121 --------------------------RSLAALTKVGL-----ADRAThlpnELSGGQKQRVAVARAI---VNNPKFILAD 166
Cdd:TIGR00630 782 gkniadvldmtveeayeffeavpsisRKLQTLCDVGLgyirlGQPAT----TLSGGEAQRIKLAKELskrSTGRTLYILD 857
                         250       260       270
                  ....*....|....*....|....*....|...
gi 446531759  167 EPTGALDTKTSTQIMDLFYELNKQGSTIIMITH 199
Cdd:TIGR00630 858 EPTTGLHFDDIKKLLEVLQRLVDKGNTVVVIEH 890
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
2-202 4.22e-06

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 47.21  E-value: 4.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759     2 INLKGITKSFQNGAESVqiLHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLdKPTTGTYELAGQNISNMTeteLARVR 81
Cdd:TIGR01271 1218 MDVQGLTAKYTEAGRAV--LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRL-LSTEGEIQIDGVSWNSVT---LQTWR 1291
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    82 nKEIGFVFQNFMLLPRlTALQNVelpliyagvDKKER--RERSLAALTKVGLADRATHLPNEL-----------SGGQKQ 148
Cdd:TIGR01271 1292 -KAFGVIPQKVFIFSG-TFRKNL---------DPYEQwsDEEIWKVAEEVGLKSVIEQFPDKLdfvlvdggyvlSNGHKQ 1360
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 446531759   149 RVAVARAIVNNPKFILADEPTGALDTKTsTQIMDLFYELNKQGSTIIMITHDRE 202
Cdd:TIGR01271 1361 LMCLARSILSKAKILLLDEPSAHLDPVT-LQIIRKTLKQSFSNCTVILSEHRVE 1413
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
142-198 4.58e-06

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 46.65  E-value: 4.58e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 142 LSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMIT 198
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIIS 448
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
21-203 9.51e-06

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 45.30  E-value: 9.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMNII--GCLDKPTTGTYELAG--------QNISNMT----------------- 73
Cdd:cd03271   11 LKNIDVDIPLGVLTCVTGVSGSGKSSLINDTlyPALARRLHLKKEQPGnhdrieglEHIDKVIvidqspigrtprsnpat 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  74 -----------------------ETELARVRNKEIGFVFQnfmllprLTALQNVELpliYAGVDKKERRersLAALTKVG 130
Cdd:cd03271   91 ytgvfdeirelfcevckgkrynrETLEVRYKGKSIADVLD-------MTVEEALEF---FENIPKIARK---LQTLCDVG 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 131 L-----ADRAThlpnELSGGQKQRVAVARAIVNNPK----FILaDEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDR 201
Cdd:cd03271  158 LgyiklGQPAT----TLSGGEAQRIKLAKELSKRSTgktlYIL-DEPTTGLHFHDVKKLLEVLQRLVDKGNTVVVIEHNL 232

                 ..
gi 446531759 202 EI 203
Cdd:cd03271  233 DV 234
PTZ00243 PTZ00243
ABC transporter; Provisional
20-199 1.02e-05

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 45.93  E-value: 1.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   20 ILHGIDVTLNQGEFTSIMGPSGSGKSTL----MNIIgcldkpttgtyELAGQNIsnmtetelaRVRNKEIGF-----VFQ 90
Cdd:PTZ00243 1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLlltfMRMV-----------EVCGGEI---------RVNGREIGAyglreLRR 1384
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   91 NFMLLPRLTAL------QNVElPLIYAGvdkkerRERSLAALTKVGLADRathLPNELSG--------------GQKQRV 150
Cdd:PTZ00243 1385 QFSMIPQDPVLfdgtvrQNVD-PFLEAS------SAEVWAALELVGLRER---VASESEGidsrvleggsnysvGQRQLM 1454
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 446531759  151 AVARAIVN-NPKFILADEPTG----ALDTKTSTQIMDLFyelnkQGSTIIMITH 199
Cdd:PTZ00243 1455 CMARALLKkGSGFILMDEATAnidpALDRQIQATVMSAF-----SAYTVITIAH 1503
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
4-224 1.18e-05

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 45.65  E-value: 1.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   4 LKGITKSFQNGaesvQILHGIDVTLNQGEFTSIMGPSGSGKSTLMN-IIGCLdKPTTGTYELAgqnisnmtetelarvRN 82
Cdd:PRK15064 322 VENLTKGFDNG----PLFKNLNLLLEAGERLAIIGENGVGKTTLLRtLVGEL-EPDSGTVKWS---------------EN 381
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  83 KEIGFV-------FQNFMLLprltalqnVELPLIYAGVDKKERRERS-LAALtkvgL--ADRATHLPNELSGGQKQRVAV 152
Cdd:PRK15064 382 ANIGYYaqdhaydFENDLTL--------FDWMSQWRQEGDDEQAVRGtLGRL----LfsQDDIKKSVKVLSGGEKGRMLF 449
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 153 ARAIVNNPKFILADEPTGALDTKTstqIMDLFYELNKQGSTIIMITHDRE-IGEAAARQIVIRDGNIVqDWRG 224
Cdd:PRK15064 450 GKLMMQKPNVLVMDEPTNHMDMES---IESLNMALEKYEGTLIFVSHDREfVSSLATRIIEITPDGVV-DFSG 518
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
20-180 1.27e-05

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 45.71  E-value: 1.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAGQNISNMTeteLARVRNKeIGFVFQNfmllprlt 99
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIG---LHDLRFK-ITIIPQD-------- 1368
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   100 alqnvelPLIYAGVDK-------KERRERSLAALTKVGLADRATHLPNEL-----------SGGQKQRVAVARAIVNNPK 161
Cdd:TIGR00957 1369 -------PVLFSGSLRmnldpfsQYSDEEVWWALELAHLKTFVSALPDKLdhecaeggenlSVGQRQLVCLARALLRKTK 1441
                          170
                   ....*....|....*....
gi 446531759   162 FILADEPTGALDTKTSTQI 180
Cdd:TIGR00957 1442 ILVLDEATAAVDLETDNLI 1460
PLN03073 PLN03073
ABC transporter F family; Provisional
26-224 1.81e-05

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 44.85  E-value: 1.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  26 VTLNQGEFTSIMGPSGSGKSTL-----MNIIGCLDKPTTGTY---ELAGQNISNM-----TETELARVRNKEIGFVFQNf 92
Cdd:PLN03073 198 VTLAFGRHYGLVGRNGTGKTTFlrymaMHAIDGIPKNCQILHveqEVVGDDTTALqcvlnTDIERTQLLEEEAQLVAQQ- 276
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  93 MLLPRLTALQNVELPLIyAGVDKKERRER-----------------SLAALTKVGL---ADRATHLPNELSGGQKQRVAV 152
Cdd:PLN03073 277 RELEFETETGKGKGANK-DGVDKDAVSQRleeiykrlelidaytaeARAASILAGLsftPEMQVKATKTFSGGWRMRIAL 355
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446531759 153 ARAIVNNPKFILADEPTGALDTKTstqIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIRDGNIVQDWRG 224
Cdd:PLN03073 356 ARALFIEPDLLLLDEPTNHLDLHA---VLWLETYLLKWPKTFIVVSHAREFLNTVVTDILHLHGQKLVTYKG 424
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
21-49 2.80e-05

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 44.63  E-value: 2.80e-05
                         10        20
                 ....*....|....*....|....*....
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMN 49
Cdd:COG0178  621 LKNVDVEIPLGVLTCVTGVSGSGKSTLVN 649
uvrA PRK00349
excinuclease ABC subunit UvrA;
21-49 2.92e-05

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 44.29  E-value: 2.92e-05
                         10        20
                 ....*....|....*....|....*....
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTLMN 49
Cdd:PRK00349 625 LKNVDVEIPLGKFTCVTGVSGSGKSTLIN 653
ABC_sbcCD cd03279
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...
24-214 3.08e-05

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.


Pssm-ID: 213246 [Multi-domain]  Cd Length: 213  Bit Score: 43.41  E-value: 3.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  24 IDVT-LNQGEFTSIMGPSGSGKSTLMNIIgcldkpttgTYELAGQNI----SNMTETELARVRNK-EIGFVFQNFMLLPR 97
Cdd:cd03279   20 IDFTgLDNNGLFLICGPTGAGKSTILDAI---------TYALYGKTPrygrQENLRSVFAPGEDTaEVSFTFQLGGKKYR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LTAlqnvelpliYAGVDKKERRErslAALTKVGLADRATHLPNE-LSGGQKQRVAVARAI-----VNNPK-----FILAD 166
Cdd:cd03279   91 VER---------SRGLDYDQFTR---IVLLPQGEFDRFLARPVStLSGGETFLASLSLALalsevLQNRGgarleALFID 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446531759 167 EPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVIR 214
Cdd:cd03279  159 EGFGTLDPEALEAVATALELIRTENRMVGVISHVEELKERIPQRLEVI 206
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
125-203 4.68e-05

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 44.05  E-value: 4.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  125 ALTKVGLadraTHLP-----NELSGGQKQRVAVARAIVN---NPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIM 196
Cdd:PRK00635  792 ALCSLGL----DYLPlgrplSSLSGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVI 867

                  ....*..
gi 446531759  197 ITHDREI 203
Cdd:PRK00635  868 IEHNMHV 874
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
20-203 4.98e-05

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 43.62  E-value: 4.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  20 ILHGIDVTLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELAgqnisnmtetelarvRNKEIGFVFQNfmllpRLT 99
Cdd:PRK10636 327 ILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLA---------------KGIKLGYFAQH-----QLE 386
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759 100 ALQNVELPLIY-AGVDKKERRERSLAALTKVGL-ADRATHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTS 177
Cdd:PRK10636 387 FLRADESPLQHlARLAPQELEQKLRDYLGGFGFqGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMR 466
                        170       180
                 ....*....|....*....|....*.
gi 446531759 178 TQIMDLFYELNkqgSTIIMITHDREI 203
Cdd:PRK10636 467 QALTEALIDFE---GALVVVSHDRHL 489
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
27-200 8.33e-05

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 42.85  E-value: 8.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  27 TLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELA------GQNIS---NMT-ETELARVRNKEIGfvfqnfmllp 96
Cdd:COG1245  362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDlkisykPQYISpdyDGTvEEFLRSANTDDFG---------- 431
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  97 rlTALQNVEL--PLiyaGVDKkeRRERSLaaltkvgladrathlpNELSGGQKQRVAVARAIVNNPKFILADEPTGALD- 173
Cdd:COG1245  432 --SSYYKTEIikPL---GLEK--LLDKNV----------------KDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDv 488
                        170       180       190
                 ....*....|....*....|....*....|...
gi 446531759 174 ------TKTSTQIMDlfyelnKQGSTIIMITHD 200
Cdd:COG1245  489 eqrlavAKAIRRFAE------NRGKTAMVVDHD 515
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
142-202 8.43e-05

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 43.02  E-value: 8.43e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446531759 142 LSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTstqiMDLFYEL--NKQGsTIIMITHDRE 202
Cdd:PRK11147 441 LSGGERNRLLLARLFLKPSNLLILDEPTNDLDVET----LELLEELldSYQG-TVLLVSHDRQ 498
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
27-200 2.26e-04

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 41.72  E-value: 2.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  27 TLNQGEFTSIMGPSGSGKSTLMNIIGCLDKPTTGTYELA------GQNIS---NMTETELARVRNKEIGFVFQNFMLLPR 97
Cdd:PRK13409 361 EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPElkisykPQYIKpdyDGTVEDLLRSITDDLGSSYYKSEIIKP 440
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  98 LtalqnvELPLIYagvdkkerrERSLaaltkvgladrathlpNELSGGQKQRVAVARAIVNNPKFILADEPTGALD---- 173
Cdd:PRK13409 441 L------QLERLL---------DKNV----------------KDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDveqr 489
                        170       180       190
                 ....*....|....*....|....*....|
gi 446531759 174 ---TKTSTQIMDlfyelnKQGSTIIMITHD 200
Cdd:PRK13409 490 lavAKAIRRIAE------EREATALVVDHD 513
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
116-213 2.61e-04

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 41.54  E-value: 2.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  116 KERRERsLAALTKVGLA----DRAThlpNELSGGQKQRVAVARAI---VNNPKFILaDEPTGALDTKTSTQIMDLFYELN 188
Cdd:TIGR00630 463 KEIRER-LGFLIDVGLDylslSRAA---GTLSGGEAQRIRLATQIgsgLTGVLYVL-DEPSIGLHQRDNRRLINTLKRLR 537
                          90       100
                  ....*....|....*....|....*
gi 446531759  189 KQGSTIIMITHDREIGEAAARQIVI 213
Cdd:TIGR00630 538 DLGNTLIVVEHDEDTIRAADYVIDI 562
PLN03140 PLN03140
ABC transporter G family member; Provisional
2-181 3.49e-04

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 41.37  E-value: 3.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759    2 INLKGITKsfqngaesVQILHGIDVTLNQGEFTSIMGPSGSGKSTLM-NIIGCLDKP-------TTGTYEL--------- 64
Cdd:PLN03140  170 INLAKKTK--------LTILKDASGIIKPSRMTLLLGPPSSGKTTLLlALAGKLDPSlkvsgeiTYNGYRLnefvprkts 241
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759   65 --AGQN---ISNMT--ET------------------ELARvRNKEIG-FVFQNFMLLPRLTALQNVELPLI--YA----G 112
Cdd:PLN03140  242 ayISQNdvhVGVMTvkETldfsarcqgvgtrydllsELAR-REKDAGiFPEAEVDLFMKATAMEGVKSSLItdYTlkilG 320
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446531759  113 VDkkerrersLAALTKVGladraTHLPNELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIM 181
Cdd:PLN03140  321 LD--------ICKDTIVG-----DEMIRGISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIV 376
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
21-47 4.28e-04

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 40.78  E-value: 4.28e-04
                         10        20
                 ....*....|....*....|....*..
gi 446531759  21 LHGIDVTLNQGEFTSIMGPSGSGKSTL 47
Cdd:COG0178   16 LKNIDVDIPRNKLVVITGLSGSGKSSL 42
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
141-200 5.10e-04

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 39.48  E-value: 5.10e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446531759 141 ELSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGS-TIIMITHD 200
Cdd:cd03222   71 DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKkTALVVEHD 131
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
17-202 2.12e-03

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 38.61  E-value: 2.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  17 SVQILHGIDV-------TLNQGEFTSIMGPSGSGKSTLMNII--------GCLDKPttGTYELAGQNisnmteTELARVR 81
Cdd:PRK10636   6 SLQIRRGVRVlldnataTINPGQKVGLVGKNGCGKSTLLALLkneisadgGSYTFP--GNWQLAWVN------QETPALP 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  82 NKEIGFVF---QNFMLLPRLTALQNVE-----LPLIYAGVDKKER---RERSLAALTKVGLADRATHLP-NELSGGQKQR 149
Cdd:PRK10636  78 QPALEYVIdgdREYRQLEAQLHDANERndghaIATIHGKLDAIDAwtiRSRAASLLHGLGFSNEQLERPvSDFSGGWRMR 157
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446531759 150 VAVARAIVNNPKFILADEPTGALDTKTstqIMDLFYELNKQGSTIIMITHDRE 202
Cdd:PRK10636 158 LNLAQALICRSDLLLLDEPTNHLDLDA---VIWLEKWLKSYQGTLILISHDRD 207
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
117-200 2.70e-03

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 38.66  E-value: 2.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446531759  117 ERRERSLAALTKVGLAdratHLP-----NELSGGQKQRVAVARAIVNNPK---FILADEPTGALDTKTSTQIMDLFYELN 188
Cdd:PRK00635 1674 KKIQKPLQALIDNGLG----YLPlgqnlSSLSLSEKIAIKIAKFLYLPPKhptLFLLDEIATSLDNQQKSALLVQLRTLV 1749
                          90
                  ....*....|..
gi 446531759  189 KQGSTIIMITHD 200
Cdd:PRK00635 1750 SLGHSVIYIDHD 1761
ABC_SMC_head cd03239
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural ...
142-213 3.02e-03

The SMC head domain belongs to the ATP-binding cassette superfamily; The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria, and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa, and each has five distinct domains: amino- and carboxy-terminal globular domains, which contain sequences characteristic of ATPases, two coiled-coil regions separating the terminal domains , and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions, including chromosome condensation, sister-chromatid cohesion, recombination, DNA repair, and epigenetic silencing of gene expression.


Pssm-ID: 213206 [Multi-domain]  Cd Length: 178  Bit Score: 37.29  E-value: 3.02e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446531759 142 LSGGQKQRVAVA-----RAIVNNPKFILaDEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREIGEAAARQIVI 213
Cdd:cd03239   95 LSGGEKSLSALAlifalQEIKPSPFYVL-DEIDAALDPTNRRRVSDMIKEMAKHTSQFIVITLKKEMFENADKLIGV 170
AAA_29 pfam13555
P-loop containing region of AAA domain;
22-48 3.11e-03

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 34.88  E-value: 3.11e-03
                          10        20
                  ....*....|....*....|....*..
gi 446531759   22 HGIDVTLNQGEFTSIMGPSGSGKSTLM 48
Cdd:pfam13555  13 DGHTIPIDPRGNTLLTGPSGSGKSTLL 39
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
139-203 5.08e-03

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 37.37  E-value: 5.08e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446531759  139 PNELSGGQKQ---RVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMITHDREI 203
Cdd:pfam13304 234 AFELSDGTKRllaLLAALLSALPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTHSPLL 301
ABC_SMC1_euk cd03275
ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of ...
32-51 5.08e-03

ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213242 [Multi-domain]  Cd Length: 247  Bit Score: 37.17  E-value: 5.08e-03
                         10        20
                 ....*....|....*....|
gi 446531759  32 EFTSIMGPSGSGKSTLMNII 51
Cdd:cd03275   23 RFTCIIGPNGSGKSNLMDAI 42
GguA NF040905
sugar ABC transporter ATP-binding protein;
142-197 9.49e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 36.69  E-value: 9.49e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446531759 142 LSGGQKQRVAVARAIVNNPKFILADEPTGALDTKTSTQIMDLFYELNKQGSTIIMI 197
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVI 460
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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