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Conserved domains on  [gi|446532139|ref|WP_000609485|]
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MULTISPECIES: hypothetical protein [Enterobacteriaceae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DarA_N pfam18788
Defence against restriction A N-terminal; This is an alpha and beta fold domain. It has a ...
 62-201 7.12e-22

Defence against restriction A N-terminal; This is an alpha and beta fold domain. It has a conserved aspartate, and an asparagine residue followed by a basic residue in a Nx+ motif. This predicted structural domain is mainly found in polyvalent proteins of phages/prophages. The P1 hdf protein, a solo version of the domain, and the Phage P1 DarA protein that contains this domain are components of the phage P1 head. The domain might be involved in a counter-restriction activity.


:

Pssm-ID: 436737  Cd Length: 101  Bit Score: 90.42  E-value: 7.12e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446532139   62 AMFESITTTRirlAQTMRAFVRALNRglngtnimAGTDEAgtdengrncIGGAIIGrVRRVANIPVLTAQIPLTDGQSTS 141
Cdd:pfam18788   1 FSFDALVVTR---EKAMKALVKAFNR--------AGATVA---------QVDVEIG-VRRKNGVSYRTAILTLSDGQTVS 59

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446532139  142 IIFHSPtADgakiksndelvAFQFLLNKRNVTHVVapiggrDVSLSQVCQALSNLIERNS 201
Cdd:pfam18788  60 IRVHNT-GD-----------IFQVLLNKKDITIVV------DLDLRAVAREIVKLAEKNS 101
DarA_C pfam18789
Defence against restriction A C-terminal; This is a mostly alpha-helical domain found in ...
 398-462 4.72e-19

Defence against restriction A C-terminal; This is a mostly alpha-helical domain found in polyvalent proteins of phages and prophages. In Phage P1, the DarA protein is a component of the phage P1 head.


:

Pssm-ID: 436738  Cd Length: 70  Bit Score: 81.30  E-value: 4.72e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446532139  398 VGKYHYALQSRPAGVGAVPDGNKAVLDRPDQAD-----QYYGYARHGIITYDRKLTDKEVSQYELLYLPD 462
Cdd:pfam18789   1 MGKYRYYSTQRPVDPGTYPKGKGNGLLEIVNFDartyvEEDSRGAWGEIEYDRPLTEEEIADYELVPAPD 70
 
Name Accession Description Interval E-value
DarA_N pfam18788
Defence against restriction A N-terminal; This is an alpha and beta fold domain. It has a ...
 62-201 7.12e-22

Defence against restriction A N-terminal; This is an alpha and beta fold domain. It has a conserved aspartate, and an asparagine residue followed by a basic residue in a Nx+ motif. This predicted structural domain is mainly found in polyvalent proteins of phages/prophages. The P1 hdf protein, a solo version of the domain, and the Phage P1 DarA protein that contains this domain are components of the phage P1 head. The domain might be involved in a counter-restriction activity.


Pssm-ID: 436737  Cd Length: 101  Bit Score: 90.42  E-value: 7.12e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446532139   62 AMFESITTTRirlAQTMRAFVRALNRglngtnimAGTDEAgtdengrncIGGAIIGrVRRVANIPVLTAQIPLTDGQSTS 141
Cdd:pfam18788   1 FSFDALVVTR---EKAMKALVKAFNR--------AGATVA---------QVDVEIG-VRRKNGVSYRTAILTLSDGQTVS 59

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446532139  142 IIFHSPtADgakiksndelvAFQFLLNKRNVTHVVapiggrDVSLSQVCQALSNLIERNS 201
Cdd:pfam18788  60 IRVHNT-GD-----------IFQVLLNKKDITIVV------DLDLRAVAREIVKLAEKNS 101
DarA_C pfam18789
Defence against restriction A C-terminal; This is a mostly alpha-helical domain found in ...
 398-462 4.72e-19

Defence against restriction A C-terminal; This is a mostly alpha-helical domain found in polyvalent proteins of phages and prophages. In Phage P1, the DarA protein is a component of the phage P1 head.


Pssm-ID: 436738  Cd Length: 70  Bit Score: 81.30  E-value: 4.72e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446532139  398 VGKYHYALQSRPAGVGAVPDGNKAVLDRPDQAD-----QYYGYARHGIITYDRKLTDKEVSQYELLYLPD 462
Cdd:pfam18789   1 MGKYRYYSTQRPVDPGTYPKGKGNGLLEIVNFDartyvEEDSRGAWGEIEYDRPLTEEEIADYELVPAPD 70
 
Name Accession Description Interval E-value
DarA_N pfam18788
Defence against restriction A N-terminal; This is an alpha and beta fold domain. It has a ...
 62-201 7.12e-22

Defence against restriction A N-terminal; This is an alpha and beta fold domain. It has a conserved aspartate, and an asparagine residue followed by a basic residue in a Nx+ motif. This predicted structural domain is mainly found in polyvalent proteins of phages/prophages. The P1 hdf protein, a solo version of the domain, and the Phage P1 DarA protein that contains this domain are components of the phage P1 head. The domain might be involved in a counter-restriction activity.


Pssm-ID: 436737  Cd Length: 101  Bit Score: 90.42  E-value: 7.12e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446532139   62 AMFESITTTRirlAQTMRAFVRALNRglngtnimAGTDEAgtdengrncIGGAIIGrVRRVANIPVLTAQIPLTDGQSTS 141
Cdd:pfam18788   1 FSFDALVVTR---EKAMKALVKAFNR--------AGATVA---------QVDVEIG-VRRKNGVSYRTAILTLSDGQTVS 59

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446532139  142 IIFHSPtADgakiksndelvAFQFLLNKRNVTHVVapiggrDVSLSQVCQALSNLIERNS 201
Cdd:pfam18788  60 IRVHNT-GD-----------IFQVLLNKKDITIVV------DLDLRAVAREIVKLAEKNS 101
DarA_C pfam18789
Defence against restriction A C-terminal; This is a mostly alpha-helical domain found in ...
 398-462 4.72e-19

Defence against restriction A C-terminal; This is a mostly alpha-helical domain found in polyvalent proteins of phages and prophages. In Phage P1, the DarA protein is a component of the phage P1 head.


Pssm-ID: 436738  Cd Length: 70  Bit Score: 81.30  E-value: 4.72e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446532139  398 VGKYHYALQSRPAGVGAVPDGNKAVLDRPDQAD-----QYYGYARHGIITYDRKLTDKEVSQYELLYLPD 462
Cdd:pfam18789   1 MGKYRYYSTQRPVDPGTYPKGKGNGLLEIVNFDartyvEEDSRGAWGEIEYDRPLTEEEIADYELVPAPD 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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