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Conserved domains on  [gi|446534039|ref|WP_000611385|]
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MULTISPECIES: SMI1/KNR4 family protein [Bacillus]

Protein Classification

SMI1/KNR4 family protein( domain architecture ID 10558574)

SMI1/KNR4 family protein may be involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation

CATH:  3.40.1580.10
Gene Ontology:  GO:0042546
SCOP:  4002285

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMI1_KNR4 pfam09346
SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1, ...
 28-125 1.47e-06

SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.


:

Pssm-ID: 430545  Cd Length: 120  Bit Score: 45.51  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534039   28 MGLILPNAYKQLLKHTNGF-VSDNGVVIFGVDIIDEMNKTYEVHE---------YAKGYVAVGSNGGGKILLMTANENAT 97
Cdd:pfam09346  14 LGVKLPEDYREFLLKTNGGgGLFEGLDLLPLEEIEEEYEDLLAEDslyfirewgLPEGLIPFADDGGGDYLCLDLRDGGE 93

                          90       100
                  ....*....|....*....|....*...
gi 446534039   98 ElVQVDSGIMDPNYATTVSENFIQWIND 125
Cdd:pfam09346  94 E-GQVYFWDEDDDELKLVADSFEEFLER 120
 
Name Accession Description Interval E-value
SMI1_KNR4 pfam09346
SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1, ...
 28-125 1.47e-06

SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.


Pssm-ID: 430545  Cd Length: 120  Bit Score: 45.51  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534039   28 MGLILPNAYKQLLKHTNGF-VSDNGVVIFGVDIIDEMNKTYEVHE---------YAKGYVAVGSNGGGKILLMTANENAT 97
Cdd:pfam09346  14 LGVKLPEDYREFLLKTNGGgGLFEGLDLLPLEEIEEEYEDLLAEDslyfirewgLPEGLIPFADDGGGDYLCLDLRDGGE 93

                          90       100
                  ....*....|....*....|....*...
gi 446534039   98 ElVQVDSGIMDPNYATTVSENFIQWIND 125
Cdd:pfam09346  94 E-GQVYFWDEDDDELKLVADSFEEFLER 120
YPO0640_fam NF038335
YrhA family protein; Members of this family include YrhA from Escherichia coli, which is found ...
 29-83 4.46e-04

YrhA family protein; Members of this family include YrhA from Escherichia coli, which is found as a pseudogene in the K-12 model strain, and YPO0640 from Yersinia pestis. Only full-length forms are used in the seed alignment for this HMM. The function of this protein family is unknown.


Pssm-ID: 468481  Cd Length: 149  Bit Score: 39.08  E-value: 4.46e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446534039  29 GLILPNAYKQLLKHTNGFvSDNGVVIFGVDI-------------IDEMNKTYEVHEYAKGYVAVGSNG 83
Cdd:NF038335  41 GIWLPPDYLEFLKISNGL-EFNGLVLYGIDQslldgepndfingLIEANEIWRENEWQDKYLFIGESD 107
 
Name Accession Description Interval E-value
SMI1_KNR4 pfam09346
SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1, ...
 28-125 1.47e-06

SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.


Pssm-ID: 430545  Cd Length: 120  Bit Score: 45.51  E-value: 1.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534039   28 MGLILPNAYKQLLKHTNGF-VSDNGVVIFGVDIIDEMNKTYEVHE---------YAKGYVAVGSNGGGKILLMTANENAT 97
Cdd:pfam09346  14 LGVKLPEDYREFLLKTNGGgGLFEGLDLLPLEEIEEEYEDLLAEDslyfirewgLPEGLIPFADDGGGDYLCLDLRDGGE 93

                          90       100
                  ....*....|....*....|....*...
gi 446534039   98 ElVQVDSGIMDPNYATTVSENFIQWIND 125
Cdd:pfam09346  94 E-GQVYFWDEDDDELKLVADSFEEFLER 120
YPO0640_fam NF038335
YrhA family protein; Members of this family include YrhA from Escherichia coli, which is found ...
 29-83 4.46e-04

YrhA family protein; Members of this family include YrhA from Escherichia coli, which is found as a pseudogene in the K-12 model strain, and YPO0640 from Yersinia pestis. Only full-length forms are used in the seed alignment for this HMM. The function of this protein family is unknown.


Pssm-ID: 468481  Cd Length: 149  Bit Score: 39.08  E-value: 4.46e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446534039  29 GLILPNAYKQLLKHTNGFvSDNGVVIFGVDI-------------IDEMNKTYEVHEYAKGYVAVGSNG 83
Cdd:NF038335  41 GIWLPPDYLEFLKISNGL-EFNGLVLYGIDQslldgepndfingLIEANEIWRENEWQDKYLFIGESD 107
SUKH_5 pfam14567
SMI1-KNR4 cell-wall; Members of this family are related to the SMI1/KNR4-like or SUKH ...
 26-125 2.47e-03

SMI1-KNR4 cell-wall; Members of this family are related to the SMI1/KNR4-like or SUKH superfamily of proteins.


Pssm-ID: 434042  Cd Length: 133  Bit Score: 36.91  E-value: 2.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534039   26 EEMGLILPNAYKQLLKHTnGFVSDNGVVIFGV---DIIDEMNKTYEVHEY--AKGYVAVGSNGGGKILLMTANENATELV 100
Cdd:pfam14567  29 EQLGIKFPNDYKEFLKEY-SDGGYGGLEILGItdpYLPEVVAYTWEYREYglPKNLIPICEDGDGYYCIDTNEGKEGEVV 107

                          90       100
                  ....*....|....*....|....*...
gi 446534039  101 ---QVDSGIMDpnyatTVSENFIQWIND 125
Cdd:pfam14567 108 fwsHEEGEFTD-----ESWPSFWEWLLD 130
SUKH_6 pfam14568
SMI1-KNR4 cell-wall; Members of this family are related to the SMI1/KNR4-like or SUKH ...
 28-123 3.37e-03

SMI1-KNR4 cell-wall; Members of this family are related to the SMI1/KNR4-like or SUKH superfamily of proteins.


Pssm-ID: 434043  Cd Length: 120  Bit Score: 36.20  E-value: 3.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446534039   28 MGLILPNAYKQLLKHTNGF--------------VSDNGVVIFGVDIIDEMNKTY-EVHEYAKGYVAVGSNGGGKILLM-T 91
Cdd:pfam14568  11 LGVKLPEDYKEFLKKYNGGyfggnefygisedsIVNDALANLLLEGILEDKELYiDEDGLPEGLLPIADDGGGDYFCFdY 90

                          90       100       110
                  ....*....|....*....|....*....|..
gi 446534039   92 ANENATELVQVDSgiMDPNYATTVSENFIQWI 123
Cdd:pfam14568  91 GENGEPKVVFWDS--EEDGSREKIADSFEEFL 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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