|
Name |
Accession |
Description |
Interval |
E-value |
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
23-451 |
0e+00 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 549.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 23 LGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKKVRKASPHRVKAPCPVYEECGGCQLQHLDYKEQLNQ 102
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 103 KRDIVVQAFEKYMNNSLEE-KIRPTLGmENPWHYRNKSQLQVGR-KDEKVITGLYKQNSHQLIDIAHCMIQHKATNEATK 180
Cdd:TIGR00479 81 KQQQVIALLERIGKFVSEPiEDVPTIG-DDPWGYRNKARLSLGRsPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 181 VVRRILEKLNVSIYNEKKQKGLVRTIVTRTAVQTGEVQVTLITTKEELPNKDQFIAEVQKQMPAVKSIMQNVNWRKTSVI 260
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 261 FGDKTFKLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGDEKIVDAYCGVGTIGLWLANDAAEVRG 340
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 341 MDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPKWVKEGWRPDVIVVDPPRTGCDDKLLETILKVKPKQVVYVSCNPS 420
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420 430
....*....|....*....|....*....|..
gi 446537868 421 SLARDVQALMK-SYEVEYVQPVDMFPHTAHVE 451
Cdd:TIGR00479 400 TLARDLEALCKaGYTIARVQPVDMFPHTGHVE 431
|
|
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
14-457 |
1.82e-180 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 508.95 E-value: 1.82e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 14 QTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKKVRKASPHRVKAPCPVYEECGGCQLQH 93
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 94 LDYKEQLNQKRDIVVQAFEKYMNNSLEEkIRPTLGMENPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDIAHCMIQHK 173
Cdd:COG2265 81 LSYEAQLELKQRVVREALERIGGLPEVE-VEPIIGSPEPWGYRNRARLSVRRTDGRLRLGFYARGSHELVDIDECPLLDP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 174 ATNEATKVVRRILEKLNvsiynekKQKGLVRTIVTRtavqtgevqvtlittkeelpnkdqfiaevqkqmpavksimqnvn 253
Cdd:COG2265 160 ALNALLPALRELLAELG-------ARRGELRHLVVR-------------------------------------------- 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 254 wrktsvifgdktfklAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGDEKIVDAYCGVGTIGLWLAN 333
Cdd:COG2265 189 ---------------AGRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLAR 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 334 DAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPKWVKEGwRPDVIVVDPPRTGCDDKLLETILKVKPKQVV 413
Cdd:COG2265 254 RAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELLWGG-RPDVVVLDPPRAGAGPEVLEALAALGPRRIV 332
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 446537868 414 YVSCNPSSLARDVQALMKS-YEVEYVQPVDMFPHTAHVENVVKLV 457
Cdd:COG2265 333 YVSCNPATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
14-451 |
1.30e-73 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 238.13 E-value: 1.30e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 14 QTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKKVRKASPHRVKAPCPVYEECGGCQLQH 93
Cdd:PRK13168 14 QIITVTIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 94 LDYKEQLNQKRDIVVQAFEKYMNNSLEEKIRPTLGmeNPWHYRNKSQLQVG--RKDEKVITGLYKQNSHQLIDIAHCMIQ 171
Cdd:PRK13168 94 LSIDAQIASKQRALEDLLKHLAGVEPEEVLPPIAG--PPWGYRRRARLSVRyvPKKGQLLVGFREKNSSDIVDIDQCPVL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 172 HKATNEATKVVRRILEKLNVsiyneKKQKGLVRTIVTrtavQTGEVQVTLITtkEELPNKD-----QFIAEvqkqmpavk 246
Cdd:PRK13168 172 VPPLSALLPPLRALLSSLSA-----KRRLGHVELAQG----DNGTALVLRHL--EPLSEADraklrAFAEQ--------- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 247 simQNVNWRktsvifgdktfkLAGKEVIQETLG--------------DLSFELSARAFFQLNPEQTVVLYDEAKKAAALT 312
Cdd:PRK13168 232 ---HGLQLY------------LQPKGPDLVHLLgpadaqlsyylpefGLRLAFSPRDFIQVNAQVNQKMVARALEWLDPQ 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 313 GDEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPK--WVKEGWrpDVIVVD 390
Cdd:PRK13168 297 PGDRVLDLFCGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDqpWALGGF--DKVLLD 374
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446537868 391 PPRTGCDDkLLETILKVKPKQVVYVSCNPSSLARDVQALMKS-YEVEYVQPVDMFPHTAHVE 451
Cdd:PRK13168 375 PPRAGAAE-VMQALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHTGHVE 435
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
95-459 |
1.85e-12 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 68.23 E-value: 1.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 95 DYKEQLNQKRDIVVQAFEKYMNNSLEEKIRPtlgmenPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDIAHCMIQHKA 174
Cdd:pfam05958 1 QYDAQLAEKKSRLKALFAPFYAPDPEVFASP------DKHYRMRAEFRIWHEGDDLYYAMFDQQTKSRIRVDQFPAASEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 175 TNEatkVVRRILEKL--NVSIYNEKKQKGLVRTIvtrtavqTGEVQVTLITTKeelPNKDQFIAEVQKQMPAVKSIMQNV 252
Cdd:pfam05958 75 INE---LMPALIAALrqDPALRHKLFQVDFLTTL-------SGEALVSLLYHK---QLDDEWRQAAEALRDALRAQGLDV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 253 NW----RKTSVIFG----DKTFKLAGKEVIQETLGDlsfelsarAFFQLNPEQTVVLYDEAKKAA-ALTGDekIVDAYCG 323
Cdd:pfam05958 142 NLigraRKQKIVLDqdyvDETLPVAGREFIYRQVEN--------SFTQPNAAVNIKMLEWACDVTqGSKGD--LLELYCG 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 324 VGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPKWVKEgwRP--------------DVIVV 389
Cdd:pfam05958 212 NGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGV--REfnrlkgidlksyncSTIFV 289
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 390 DPPRTGCDDKLLETILKVKpkQVVYVSCNPSSLARDVQALMKSYEVEYVQPVDMFPHTAHVENVVKLVRK 459
Cdd:pfam05958 290 DPPRAGLDPETLKLVQAYP--RILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEKK 357
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
316-417 |
6.35e-09 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 53.59 E-value: 6.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 316 KIVDAYCGVGTIGLWLAND-AAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPKWVKegwRPDVIVVDPPRT 394
Cdd:cd02440 1 RVLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADE---SFDVIISDPPLH 77
|
90 100
....*....|....*....|....*..
gi 446537868 395 GCDD---KLLETILKV-KPKQVVYVSC 417
Cdd:cd02440 78 HLVEdlaRFLEEARRLlKPGGVLVLTL 104
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
23-451 |
0e+00 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 549.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 23 LGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKKVRKASPHRVKAPCPVYEECGGCQLQHLDYKEQLNQ 102
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 103 KRDIVVQAFEKYMNNSLEE-KIRPTLGmENPWHYRNKSQLQVGR-KDEKVITGLYKQNSHQLIDIAHCMIQHKATNEATK 180
Cdd:TIGR00479 81 KQQQVIALLERIGKFVSEPiEDVPTIG-DDPWGYRNKARLSLGRsPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 181 VVRRILEKLNVSIYNEKKQKGLVRTIVTRTAVQTGEVQVTLITTKEELPNKDQFIAEVQKQMPAVKSIMQNVNWRKTSVI 260
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 261 FGDKTFKLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGDEKIVDAYCGVGTIGLWLANDAAEVRG 340
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 341 MDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPKWVKEGWRPDVIVVDPPRTGCDDKLLETILKVKPKQVVYVSCNPS 420
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420 430
....*....|....*....|....*....|..
gi 446537868 421 SLARDVQALMK-SYEVEYVQPVDMFPHTAHVE 451
Cdd:TIGR00479 400 TLARDLEALCKaGYTIARVQPVDMFPHTGHVE 431
|
|
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
14-457 |
1.82e-180 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 508.95 E-value: 1.82e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 14 QTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKKVRKASPHRVKAPCPVYEECGGCQLQH 93
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 94 LDYKEQLNQKRDIVVQAFEKYMNNSLEEkIRPTLGMENPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDIAHCMIQHK 173
Cdd:COG2265 81 LSYEAQLELKQRVVREALERIGGLPEVE-VEPIIGSPEPWGYRNRARLSVRRTDGRLRLGFYARGSHELVDIDECPLLDP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 174 ATNEATKVVRRILEKLNvsiynekKQKGLVRTIVTRtavqtgevqvtlittkeelpnkdqfiaevqkqmpavksimqnvn 253
Cdd:COG2265 160 ALNALLPALRELLAELG-------ARRGELRHLVVR-------------------------------------------- 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 254 wrktsvifgdktfklAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGDEKIVDAYCGVGTIGLWLAN 333
Cdd:COG2265 189 ---------------AGRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLAR 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 334 DAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPKWVKEGwRPDVIVVDPPRTGCDDKLLETILKVKPKQVV 413
Cdd:COG2265 254 RAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELLWGG-RPDVVVLDPPRAGAGPEVLEALAALGPRRIV 332
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 446537868 414 YVSCNPSSLARDVQALMKS-YEVEYVQPVDMFPHTAHVENVVKLV 457
Cdd:COG2265 333 YVSCNPATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
14-451 |
1.30e-73 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 238.13 E-value: 1.30e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 14 QTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKKVRKASPHRVKAPCPVYEECGGCQLQH 93
Cdd:PRK13168 14 QIITVTIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 94 LDYKEQLNQKRDIVVQAFEKYMNNSLEEKIRPTLGmeNPWHYRNKSQLQVG--RKDEKVITGLYKQNSHQLIDIAHCMIQ 171
Cdd:PRK13168 94 LSIDAQIASKQRALEDLLKHLAGVEPEEVLPPIAG--PPWGYRRRARLSVRyvPKKGQLLVGFREKNSSDIVDIDQCPVL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 172 HKATNEATKVVRRILEKLNVsiyneKKQKGLVRTIVTrtavQTGEVQVTLITtkEELPNKD-----QFIAEvqkqmpavk 246
Cdd:PRK13168 172 VPPLSALLPPLRALLSSLSA-----KRRLGHVELAQG----DNGTALVLRHL--EPLSEADraklrAFAEQ--------- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 247 simQNVNWRktsvifgdktfkLAGKEVIQETLG--------------DLSFELSARAFFQLNPEQTVVLYDEAKKAAALT 312
Cdd:PRK13168 232 ---HGLQLY------------LQPKGPDLVHLLgpadaqlsyylpefGLRLAFSPRDFIQVNAQVNQKMVARALEWLDPQ 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 313 GDEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPK--WVKEGWrpDVIVVD 390
Cdd:PRK13168 297 PGDRVLDLFCGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDqpWALGGF--DKVLLD 374
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446537868 391 PPRTGCDDkLLETILKVKPKQVVYVSCNPSSLARDVQALMKS-YEVEYVQPVDMFPHTAHVE 451
Cdd:PRK13168 375 PPRAGAAE-VMQALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHTGHVE 435
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
194-459 |
3.50e-46 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 162.35 E-value: 3.50e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 194 YNEKKQKG-LVRTIVTRTAVQtGEVQVTLIT-TKEELPNKDQFIAEVQKQMPAVKSIMQNVNWRKTSVIFGDKTFKLAGK 271
Cdd:PRK03522 53 YNVARKRGeLKYILLTESQSD-GELMLRFVLrSETKLARLRRALPWLQAQLPQLKVISVNIQPVHMAILEGEEEIFLTEQ 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 272 EVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGDEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDA 351
Cdd:PRK03522 132 QALPERFNGVPLFIRPQSFFQTNPAVAAQLYATARDWVRELPPRSMWDLFCGVGGFGLHCATPGMQLTGIEISAEAIACA 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 352 RKNAKRHGFTNTKYEAGKAEQWLpkwVKEGWRPDVIVVDPPRTGCDDKLLETILKVKPKQVVYVSCNPSSLARDVQAlMK 431
Cdd:PRK03522 212 KQSAAELGLTNVQFQALDSTQFA---TAQGEVPDLVLVNPPRRGIGKELCDYLSQMAPRFILYSSCNAQTMAKDLAH-LP 287
|
250 260
....*....|....*....|....*...
gi 446537868 432 SYEVEYVQPVDMFPHTAHVENVVKLVRK 459
Cdd:PRK03522 288 GYRIERVQLFDMFPHTAHYEVLTLLVRQ 315
|
|
| meth_trns_rumB |
TIGR02085 |
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases ... |
80-458 |
1.73e-41 |
|
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases designated RumB, formerly YbjF. Members act on 23S rRNA U747 and the equivalent position in other proteobacterial species. This family is homologous to the other 23S rRNA methyltransferase RumA and to the tRNA methyltransferase TrmA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 131140 Cd Length: 374 Bit Score: 151.53 E-value: 1.73e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 80 CPVYE--ECGGCQLQHLDYKEQLNQKRDIVVQAFEKymNNSLEEKIRPTLGMENPwhYRNKSQLQVGRKDEKVITGLYKq 157
Cdd:TIGR02085 2 CAFYIqgRCRSCQWLAQPYSEQLTNKQQHLKELLAP--NATVVQWLAPVTSAEQA--FRNKAKMVVSGSVERPILGILH- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 158 NSHQLIDIAHCMIQHKATNEATKVVRRILEKLNVSIYNEKKQKGLVRTIVTRTAVQTGEVQVTLITTKE-ELPNKDQFIA 236
Cdd:TIGR02085 77 RDGTPLDLCDCPLYPQSFQPVFAYLKNFIARAGLTPYNVAKKKGELKFILLTESENSGQLMLRFVLRSEtKLAQIRRALP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 237 EVQKQMPAVKSIMQNVNWRKTSVIFGDKTFKLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGDEK 316
Cdd:TIGR02085 157 WLIEQLPQLEVISVNIQPVHMAILEGEEEIFLTEQQALPERFNDVPLVIRPQSFFQTNPKVAAQLYATARQWVREIPVTQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 317 IVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLpkwVKEGWRPDVIVVDPPRTGC 396
Cdd:TIGR02085 237 MWDLFCGVGGFGLHCAGPDTQLTGIEIESEAIACAQQSAQMLGLDNLSFAALDSAKFA---TAQMSAPELVLVNPPRRGI 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446537868 397 DDKLLETILKVKPKQVVYVSCNPSSLARDVQALmKSYEVEYVQPVDMFPHTAHVENVVKLVR 458
Cdd:TIGR02085 314 GKELCDYLSQMAPKFILYSSCNAQTMAKDIAEL-SGYQIERVQLFDMFPHTSHYEVLTLLVR 374
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
86-459 |
3.00e-20 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 91.81 E-value: 3.00e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 86 CGGCQLQHLDYKEQLNQKRDIVVQAFEKYMNNSLEekIRPTlgmeNPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDI 165
Cdd:PRK05031 1 MTPECLPPEQYEAQLAEKVARLKELFAPFSAPEPE--VFRS----PPSHYRMRAEFRIWHEGDDLYYAMFDQQTKQRIRI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 166 AHCMIQHKATNEATKvvrRILEKLnvsiyneKKQKGLVRTI--VTRTAVQTGEVQVTLITTKeelPNKDQFIAEVQkqmp 243
Cdd:PRK05031 75 DQFPIASELINALMP---ALLAAL-------RANPVLRHKLfqVDFLSTLSGEILVSLLYHK---KLDEEWEQAAK---- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 244 AVKSIMQNVNW----RKTSVIFG----DKTFKLAGKEviqetlgdLSFELSARAFFQLNPEQTVVLYDEAKKAAA-LTGD 314
Cdd:PRK05031 138 ALRDALFNVHLigrsRKQKIVLDqdyvDERLPVAGRE--------FIYRQVENSFTQPNAAVNEKMLEWALDATKgSKGD 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 315 ekIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAE---QWLPKwVKEGWR-------- 383
Cdd:PRK05031 210 --LLELYCGNGNFTLALARNFRRVLATEISKPSVAAAQYNIAANGIDNVQIIRMSAEeftQAMNG-VREFNRlkgidlks 286
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446537868 384 --PDVIVVDPPRTGCDDKLLETILKVKpkQVVYVSCNPSSLARDVQALMKSYEVEYVQPVDMFPHTAHVENVVKLVRK 459
Cdd:PRK05031 287 ynFSTIFVDPPRAGLDDETLKLVQAYE--RILYISCNPETLCENLETLSQTHKVERFALFDQFPYTHHMECGVLLEKK 362
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
95-459 |
1.85e-12 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 68.23 E-value: 1.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 95 DYKEQLNQKRDIVVQAFEKYMNNSLEEKIRPtlgmenPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDIAHCMIQHKA 174
Cdd:pfam05958 1 QYDAQLAEKKSRLKALFAPFYAPDPEVFASP------DKHYRMRAEFRIWHEGDDLYYAMFDQQTKSRIRVDQFPAASEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 175 TNEatkVVRRILEKL--NVSIYNEKKQKGLVRTIvtrtavqTGEVQVTLITTKeelPNKDQFIAEVQKQMPAVKSIMQNV 252
Cdd:pfam05958 75 INE---LMPALIAALrqDPALRHKLFQVDFLTTL-------SGEALVSLLYHK---QLDDEWRQAAEALRDALRAQGLDV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 253 NW----RKTSVIFG----DKTFKLAGKEVIQETLGDlsfelsarAFFQLNPEQTVVLYDEAKKAA-ALTGDekIVDAYCG 323
Cdd:pfam05958 142 NLigraRKQKIVLDqdyvDETLPVAGREFIYRQVEN--------SFTQPNAAVNIKMLEWACDVTqGSKGD--LLELYCG 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 324 VGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPKWVKEgwRP--------------DVIVV 389
Cdd:pfam05958 212 NGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGV--REfnrlkgidlksyncSTIFV 289
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 390 DPPRTGCDDKLLETILKVKpkQVVYVSCNPSSLARDVQALMKSYEVEYVQPVDMFPHTAHVENVVKLVRK 459
Cdd:pfam05958 290 DPPRAGLDPETLKLVQAYP--RILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEKK 357
|
|
| TRAM |
pfam01938 |
TRAM domain; This small domain has no known function. However it may perform a nucleic acid ... |
9-66 |
2.85e-12 |
|
TRAM domain; This small domain has no known function. However it may perform a nucleic acid binding role (Bateman A. unpublished observation).
Pssm-ID: 396497 [Multi-domain] Cd Length: 59 Bit Score: 61.46 E-value: 2.85e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 446537868 9 KLEVGQTFPVTIKRLGINGEGVGYFKR-QVVFIPGALPGEEVVAETTKIQRGFAEAKVK 66
Cdd:pfam01938 1 RRYVGQTQEVLVEGLSSNGEGIGRTDNgKVVFVPGALPGEFVEVKITKVKRNYLRGELL 59
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
311-443 |
1.13e-09 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 56.66 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 311 LTGDEKIVDAYCGVGTIGLWLA---NDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQwLPKWVKEGwRPDVI 387
Cdd:pfam13847 1 IDKGMRVLDLGCGTGHLSFELAeelGPNAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEE-LPELLEDD-KFDVV 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446537868 388 --------VVDPprtgcdDKLLETILKVKPKQVVYVSCNPSSLArDVQALMKSYEVEYVQPVDM 443
Cdd:pfam13847 79 isncvlnhIPDP------DKVLQEILRVLKPGGRLIISDPDSLA-ELPAHVKEDSTYYAGCVGG 135
|
|
| COG3269 |
COG3269 |
Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; |
2-65 |
4.40e-09 |
|
Predicted RNA-binding protein, contains TRAM domain [General function prediction only];
Pssm-ID: 442500 [Multi-domain] Cd Length: 129 Bit Score: 54.67 E-value: 4.40e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446537868 2 IQKQHESKLEVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKV 65
Cdd:COG3269 62 EAQELTPPVEEGEEYEVEIEDIGKKGDGIARVEGFVIFVPGAEVGDRVKVKITKVKRNFAFAEV 125
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
316-417 |
6.35e-09 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 53.59 E-value: 6.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 316 KIVDAYCGVGTIGLWLAND-AAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPKWVKegwRPDVIVVDPPRT 394
Cdd:cd02440 1 RVLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADE---SFDVIISDPPLH 77
|
90 100
....*....|....*....|....*..
gi 446537868 395 GCDD---KLLETILKV-KPKQVVYVSC 417
Cdd:cd02440 78 HLVEdlaRFLEEARRLlKPGGVLVLTL 104
|
|
| RlmK |
COG1092 |
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ... |
306-392 |
2.24e-08 |
|
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification
Pssm-ID: 440709 [Multi-domain] Cd Length: 392 Bit Score: 55.96 E-value: 2.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 306 KKAAALTGDEKIVDAYCGVGTIGLW-LANDAAEVRGMDVIPEAIEDARKNAKRHGFTNT-KYEAGKAEQWLPKWVKEGWR 383
Cdd:COG1092 209 ARVAELAKGKRVLNLFSYTGGFSVHaAAGGAKSVTSVDLSATALEWAKENAALNGLDDRhEFVQADAFDWLRELAREGER 288
|
....*....
gi 446537868 384 PDVIVVDPP 392
Cdd:COG1092 289 FDLIILDPP 297
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
309-392 |
6.13e-07 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 49.18 E-value: 6.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 309 AALTGDEKIVDAYCGVGTI---GLWLandAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQwLPKWVKegwRPD 385
Cdd:COG1041 22 AGAKEGDTVLDPFCGTGTIlieAGLL---GRRVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARD-LPLADE---SVD 94
|
....*..
gi 446537868 386 VIVVDPP 392
Cdd:COG1041 95 AIVTDPP 101
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
311-431 |
9.20e-06 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 46.45 E-value: 9.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 311 LTGDEKIVDAYCGVGTIGLWLAN-DAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKAEQWLPkwVKEGwRPDVIVV 389
Cdd:COG0500 24 LPKGGRVLDLGCGTGRNLLALAArFGGRVIGIDLSPEAIALARARAAKAGLGNVEFLVADLAELDP--LPAE-SFDLVVA 100
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 446537868 390 dpprTGC----DDKLLETILK-----VKPKQVVYVSCNPSSLARDVQALMK 431
Cdd:COG0500 101 ----FGVlhhlPPEEREALLRelaraLKPGGVLLLSASDAAAALSLARLLL 147
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
307-367 |
9.26e-06 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 46.05 E-value: 9.26e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446537868 307 KAAALTGDEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEA 367
Cdd:PRK14968 17 ENAVDKKGDRVLEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRNNGVEV 77
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
302-375 |
1.02e-05 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 44.98 E-value: 1.02e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446537868 302 YDEAK---KAAALTGDEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFtNTKYEAGKAEQwLP 375
Cdd:COG2226 8 YDGREallAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAED-LP 82
|
|
| UPF0020 |
pfam01170 |
Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated ... |
305-395 |
1.25e-05 |
|
Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains.
Pssm-ID: 395932 [Multi-domain] Cd Length: 184 Bit Score: 45.81 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 305 AKKAAAL------TGDEKIVDAYCGVGTI-------------GLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKy 365
Cdd:pfam01170 14 ETLAAAMvnlagwKPGDPLLDPMCGSGTIlieaalmganiapGKFDARVRAPLYGSDIDRRMVQGARLNAENAGVGDLI- 92
|
90 100 110
....*....|....*....|....*....|....
gi 446537868 366 eagKAEQWLPKWVKEGWRP-DVIVVDPP---RTG 395
Cdd:pfam01170 93 ---EFVQADAADLPLLEGSvDVIVTNPPygiRLG 123
|
|
| PRK09328 |
PRK09328 |
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional |
295-392 |
4.70e-05 |
|
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
Pssm-ID: 236467 [Multi-domain] Cd Length: 275 Bit Score: 45.15 E-value: 4.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 295 PEqTVVLYDEAKKAAALTGDEKIVDAYCGVGTIGLWLA--NDAAEVRGMDVIPEAIEDARKNAKRHGFTNTK------YE 366
Cdd:PRK09328 91 PE-TEELVEWALEALLLKEPLRVLDLGTGSGAIALALAkeRPDAEVTAVDISPEALAVARRNAKHGLGARVEflqgdwFE 169
|
90 100
....*....|....*....|....*.
gi 446537868 367 AGKAEQWlpkwvkegwrpDVIVVDPP 392
Cdd:PRK09328 170 PLPGGRF-----------DLIVSNPP 184
|
|
| PRK12336 |
PRK12336 |
translation initiation factor IF-2 subunit beta; Provisional |
2-62 |
5.04e-05 |
|
translation initiation factor IF-2 subunit beta; Provisional
Pssm-ID: 183451 [Multi-domain] Cd Length: 201 Bit Score: 44.17 E-value: 5.04e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446537868 2 IQKQHESKLEVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKI--QRGFAE 62
Cdd:PRK12336 137 SSETQREAIEEGKTYEVEITGTGRKGDGVAKKGKYTIFVPGAKKGEVVKVKIKKIsgNLAFAE 199
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
316-406 |
5.53e-05 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 44.03 E-value: 5.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 316 KIVDAYCGVGTIGLWLA--NDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGkaeqwlpkWVKEGWRP---DVIVVD 390
Cdd:COG2813 52 RVLDLGCGYGVIGLALAkrNPEARVTLVDVNARAVELARANAAANGLENVEVLWS--------DGLSGVPDgsfDLILSN 123
|
90
....*....|....*....
gi 446537868 391 PP-RTG--CDDKLLETILK 406
Cdd:COG2813 124 PPfHAGraVDKEVAHALIA 142
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
316-392 |
1.21e-04 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 42.58 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 316 KIVDAYCGVGTIGLWLA--NDAAEVRGMDVIPEAIEDARKNAKRHGFTNTKYEAGKA-EQWLPKwvkegwRPDVIVVDPP 392
Cdd:pfam05175 34 KVLDLGCGAGVLGAALAkeSPDAELTMVDINARALESARENLAANGLENGEVVASDVySGVEDG------KFDLIISNPP 107
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
322-373 |
1.82e-04 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 40.24 E-value: 1.82e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446537868 322 CGVGTIGLWLANDA-AEVRGMDVIPEAIEDARKNAKRHGFtNTKYEAGKAEQW 373
Cdd:pfam13649 6 CGTGRLTLALARRGgARVTGVDLSPEMLERARERAAEAGL-NVEFVQGDAEDL 57
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
308-373 |
2.74e-04 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 40.77 E-value: 2.74e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446537868 308 AAALTGDEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHgftNTKYEAGKAEQW 373
Cdd:COG2227 19 ARLLPAGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAEL---NVDFVQGDLEDL 81
|
|
| HemK |
COG2890 |
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ... |
295-362 |
5.86e-04 |
|
Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442135 [Multi-domain] Cd Length: 282 Bit Score: 41.67 E-value: 5.86e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 295 PEqTVVLYDEAKKAAALTGDEKIVDAYCGVGTIG--LWLANDAAEVRGMDVIPEAIEDARKNAKRHGFTN 362
Cdd:COG2890 95 PE-TEELVELALALLPAGAPPRVLDLGTGSGAIAlaLAKERPDARVTAVDISPDALAVARRNAERLGLED 163
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
301-353 |
1.14e-03 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 39.98 E-value: 1.14e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446537868 301 LYDEAKKAAALTGDEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARK 353
Cdd:COG4976 34 LAEELLARLPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKARE 86
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
308-392 |
2.01e-03 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 39.74 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 308 AAALTGDEKIVDAYCGVGTIGLWLA--NDAAEVRGMDVIPEAIEDARKNAKRHGFTN-TKYEAGKAEQWLPKWVKEgwRP 384
Cdd:COG4123 32 FAPVKKGGRVLDLGTGTGVIALMLAqrSPGARITGVEIQPEAAELARRNVALNGLEDrITVIHGDLKEFAAELPPG--SF 109
|
....*...
gi 446537868 385 DVIVVDPP 392
Cdd:COG4123 110 DLVVSNPP 117
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
318-361 |
3.03e-03 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 36.87 E-value: 3.03e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 446537868 318 VDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFT 361
Cdd:pfam08241 1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGLT 44
|
|
| Trm5 |
COG2520 |
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ... |
221-357 |
7.25e-03 |
|
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442010 [Multi-domain] Cd Length: 333 Bit Score: 38.30 E-value: 7.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 221 LITTKEELPNKDQFIAE-VQKQMPAVKSImqnvnWRKTSVIFGD----KTFKLAGkEVIQETL----GdLSFELS-ARAF 290
Cdd:COG2520 90 IIKIPDELEEYKEEIAEaILESHPNVKTV-----LAKASGVEGEfrvpELELLAG-EGRTETIhrenG-CRFKLDvAKVY 162
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446537868 291 FqlNPeqtvVLYDEAKKAAALTGD-EKIVDAYCGVGTIGLWLA-NDAAEVRGMDVIPEAIEDARKNAKR 357
Cdd:COG2520 163 F--SP----RLATERLRIAELVKPgERVLDMFAGVGPFSIPIAkRSGAKVVAIDINPDAVEYLKENIRL 225
|
|
| PRK07580 |
PRK07580 |
Mg-protoporphyrin IX methyl transferase; Validated |
306-374 |
9.98e-03 |
|
Mg-protoporphyrin IX methyl transferase; Validated
Pssm-ID: 236059 [Multi-domain] Cd Length: 230 Bit Score: 37.51 E-value: 9.98e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446537868 306 KKAAALTGdEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDARKNAKRHGFT-NTKYEAGKAEQWL 374
Cdd:PRK07580 57 PADGDLTG-LRILDAGCGVGSLSIPLARRGAKVVASDISPQMVEEARERAPEAGLAgNITFEVGDLESLL 125
|
|
| |
