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Conserved domains on  [gi|446539250|ref|WP_000616596|]
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MULTISPECIES: 1-acyl-sn-glycerol-3-phosphate acyltransferase [Bacillus]

Protein Classification

lysophospholipid acyltransferase family protein( domain architecture ID 11415180)

lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid; 1-acyl-sn-glycerol-3-phosphate acyltransferase, for example, converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position by utilizing either acyl-CoA or acyl-ACP as the fatty acyl donor;

CATH:  1.10.1200.50
EC:  2.3.1.-
Gene Ontology:  GO:0008654|GO:0016746
PubMed:  18718904|18931347
SCOP:  4003349

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 39-239 1.26e-70

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


:

Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 215.26  E-value: 1.26e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  39 NVVYKTTNWFGKKMVRVAGGAIEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELM 118
Cdd:COG0204   10 RFRYRLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLAALPRPVRFVAKKELFKIPLLGWLLRAL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 119 NCVFMVRNDRRQSLQAIKDGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFEaNGNR 198
Cdd:COG0204   90 GAIPVDRSKRRAALRALRQAVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALP-KGFL 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 446539250 199 MKPAHATVTISKPITSEEYANMDIKELTKHTQDVIASQLHK 239
Cdd:COG0204  169 PRPGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAE 209
 
Name Accession Description Interval E-value
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 39-239 1.26e-70

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 215.26  E-value: 1.26e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  39 NVVYKTTNWFGKKMVRVAGGAIEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELM 118
Cdd:COG0204   10 RFRYRLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLAALPRPVRFVAKKELFKIPLLGWLLRAL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 119 NCVFMVRNDRRQSLQAIKDGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFEaNGNR 198
Cdd:COG0204   90 GAIPVDRSKRRAALRALRQAVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALP-KGFL 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 446539250 199 MKPAHATVTISKPITSEEYANMDIKELTKHTQDVIASQLHK 239
Cdd:COG0204  169 PRPGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAE 209
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 50-230 1.88e-64

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 198.26  E-value: 1.88e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  50 KKMVRVAGGAIEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRR 129
Cdd:cd07989    2 RLLLRLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 130 QSLQAIKDGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFEANGNRMKPAHATVTIS 209
Cdd:cd07989   82 SAREALREAIEALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGRVTVRIG 161

                        170       180
                 ....*....|....*....|...
gi 446539250 210 KPITSE--EYANMDIKELTKHTQ 230
Cdd:cd07989  162 EPIPPEglELAEEDRKELREKVR 184
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 60-185 2.27e-39

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 132.47  E-value: 2.27e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250   60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIKDGI 139
Cdd:TIGR00530   4 VEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAIATALKAAI 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 446539250  140 ELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTL 185
Cdd:TIGR00530  84 EVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVL 129
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
 60-237 4.29e-39

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 134.47  E-value: 4.29e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVPK-DKPVLVVSNHQSNMDIPVLLgYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIKDG 138
Cdd:PLN02901  37 IEVEGLENLPSpDEPAVYVSNHQSFLDIYTLF-HLGRPFKFISKTSIFLIPIIGWAMYMTGHIPLKRMDRRSQLECLKRC 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 139 IELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFeANG--NRMKPAHATVTISKPITSEe 216
Cdd:PLN02901 116 MELLKKGASVFFFPEGTRSKDGKLAAFKKGAFSVAAKTGVPVVPITLVGTGKIM-PNGkeGILNPGSVKVVIHPPIEGS- 193

                        170       180
                 ....*....|....*....|.
gi 446539250 217 yanmDIKELTKHTQDVIASQL 237
Cdd:PLN02901 194 ----DADELCNEARKVIAESL 210
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 74-188 4.70e-37

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 126.32  E-value: 4.70e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250    74 VLVVSNHQSNMDIPVLLGYLNKPIG---FVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIKDGIELLKNGHSIVI 150
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKLGrvrFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVELLKEGEWLLI 80

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 446539250   151 FPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGT 188
Cdd:smart00563  81 FPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIRGT 118
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 60-185 6.78e-37

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 126.24  E-value: 6.78e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250   60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVL---LGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIK 136
Cdd:pfam01553   2 IEVHGLENLPRGGPAIVVANHQSYLDVLLLslaLYKRGRPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLE 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 446539250  137 DGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTL 185
Cdd:pfam01553  82 YLVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAI 130
 
Name Accession Description Interval E-value
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 39-239 1.26e-70

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 215.26  E-value: 1.26e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  39 NVVYKTTNWFGKKMVRVAGGAIEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELM 118
Cdd:COG0204   10 RFRYRLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLAALPRPVRFVAKKELFKIPLLGWLLRAL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 119 NCVFMVRNDRRQSLQAIKDGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFEaNGNR 198
Cdd:COG0204   90 GAIPVDRSKRRAALRALRQAVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALP-KGFL 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 446539250 199 MKPAHATVTISKPITSEEYANMDIKELTKHTQDVIASQLHK 239
Cdd:COG0204  169 PRPGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAE 209
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 50-230 1.88e-64

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 198.26  E-value: 1.88e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  50 KKMVRVAGGAIEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRR 129
Cdd:cd07989    2 RLLLRLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 130 QSLQAIKDGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFEANGNRMKPAHATVTIS 209
Cdd:cd07989   82 SAREALREAIEALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGRVTVRIG 161

                        170       180
                 ....*....|....*....|...
gi 446539250 210 KPITSE--EYANMDIKELTKHTQ 230
Cdd:cd07989  162 EPIPPEglELAEEDRKELREKVR 184
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 60-185 2.27e-39

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 132.47  E-value: 2.27e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250   60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIKDGI 139
Cdd:TIGR00530   4 VEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAIATALKAAI 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 446539250  140 ELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTL 185
Cdd:TIGR00530  84 EVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVL 129
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
 60-237 4.29e-39

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 134.47  E-value: 4.29e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVPK-DKPVLVVSNHQSNMDIPVLLgYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIKDG 138
Cdd:PLN02901  37 IEVEGLENLPSpDEPAVYVSNHQSFLDIYTLF-HLGRPFKFISKTSIFLIPIIGWAMYMTGHIPLKRMDRRSQLECLKRC 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 139 IELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGTYKMFeANG--NRMKPAHATVTISKPITSEe 216
Cdd:PLN02901 116 MELLKKGASVFFFPEGTRSKDGKLAAFKKGAFSVAAKTGVPVVPITLVGTGKIM-PNGkeGILNPGSVKVVIHPPIEGS- 193

                        170       180
                 ....*....|....*....|.
gi 446539250 217 yanmDIKELTKHTQDVIASQL 237
Cdd:PLN02901 194 ----DADELCNEARKVIAESL 210
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 74-188 4.70e-37

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 126.32  E-value: 4.70e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250    74 VLVVSNHQSNMDIPVLLGYLNKPIG---FVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIKDGIELLKNGHSIVI 150
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKLGrvrFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVELLKEGEWLLI 80

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 446539250   151 FPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGT 188
Cdd:smart00563  81 FPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIRGT 118
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 60-185 6.78e-37

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 126.24  E-value: 6.78e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250   60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVL---LGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIK 136
Cdd:pfam01553   2 IEVHGLENLPRGGPAIVVANHQSYLDVLLLslaLYKRGRPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLE 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 446539250  137 DGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTL 185
Cdd:pfam01553  82 YLVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAI 130
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 60-237 1.38e-25

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 98.64  E-value: 1.38e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVL-----LGYLNKPIGFVSKAEIKKFPVVpTWmelMNCVFMVRNDRRQSLQA 134
Cdd:cd06551   14 LEVKGPPPPPGGGPVLFVSNHSSWWDGLILfllleRGLRRDVYGLMDEELLERYPFF-TR---LGAFSVDRDSPRSAAKS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 135 IKDGIELLKN-GHSIVIFPEGTRSKGGE-IGEFKAGSFHLAVKSGVAILPVTLDGTYKMFEANGnrmkpaHATVTISKPI 212
Cdd:cd06551   90 LKYVARLLSKpGSVVWIFPEGTRTRRDKrPLQFKPGVAHLAEKAGVPIVPVALRYTFELFEQFP------EIFVRIGPPI 163

                        170       180
                 ....*....|....*....|....*
gi 446539250 213 TSEEYAnmDIKELTKHTQDVIASQL 237
Cdd:cd06551  164 PYAETA--LGEELAAELANRLTRLL 186
PRK08633 PRK08633
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
 60-212 2.66e-21

2-acyl-glycerophospho-ethanolamine acyltransferase; Validated


Pssm-ID: 236315 [Multi-domain]  Cd Length: 1146  Bit Score: 92.29  E-value: 2.66e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250   60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIKdgi 139
Cdd:PRK08633  429 LRVEGRENIPAKGGALLLGNHVSWIDWALLQAASPRPIRFVMERSIYEKWYLKWFFKLFGVIPISSGGSKESLEFIR--- 505

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  140 ELLKNGHSIVIFPEGTRSKGGEIGEFKAGsFHLAVK-SGVAILPVTLDGTY-KMFEANGNRMK---PAHA----TVTISK 210
Cdd:PRK08633  506 KALDDGEVVCIFPEGAITRNGQLNEFKRG-FELIVKgTDVPIIPFYIRGLWgSIFSRASGKFLwrwPTRIpypvTVAFGK 584


                  ..
gi 446539250  211 PI 212
Cdd:PRK08633  585 PM 586
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 52-185 5.23e-18

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 79.19  E-value: 5.23e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  52 MVRVAGGA-IEVNGLENVPKDkPVLVVSNHQSNMDIPVLLGYLnkPIGFVSKAEIKKFPVVPTWMELMNCVFMVR---ND 127
Cdd:cd07991    4 LLFAFGFYvIKVHGKPDPPEA-PRIIVANHTSFIDPLILFSDL--FPSIVAKKELGKLPFIGTILRALGCIFVDRsepKD 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446539250 128 RRQSLQAIKDgIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFhlavKSGVAILPVTL 185
Cdd:cd07991   81 RKKVVEEIKE-RATDPNWPPILIFPEGTTTNGKALIMFKKGAF----EPGVPVQPVAI 133
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 60-227 6.58e-18

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 78.84  E-value: 6.58e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVPKDKPVLVVSNHQ-SNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVR-NDRRQSLQAIKD 137
Cdd:cd07992   16 ITVVGRENVPKDGPVIFLGNHPnALIDPLLLAATLRRPVRFLAKADLFKNPLIGWLLESFGAIPVYRpKDLARGGIGKIS 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 138 -------GIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLA------VKSGVAILPVTLdgTYkmfeanGNRMKPA-H 203
Cdd:cd07992   96 naavfdaVGEALKAGGAIGIFPEGGSHDRPRLLPLKAGAARMAlealeaGQKDVKIVPVGL--NY------EDKSRFRsR 167

                        170       180
                 ....*....|....*....|....
gi 446539250 204 ATVTISKPITSEEYANMDIKELTK 227
Cdd:cd07992  168 VLVEFGKPISVSAFEEAEASRDVE 191
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 75-237 5.94e-15

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 71.58  E-value: 5.94e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  75 LVVSNHQSNMDIPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQSLQAIKDGIELLKNGH-SIVIFPE 153
Cdd:PRK15018  68 IYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRiSIWMFPE 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 154 GTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGTYKmfEANGNRMKPAHATVTISKPITSEEYANMDIKELTKHTQDVI 233
Cdd:PRK15018 148 GTRSRGRGLLPFKTGAFHAAIAAGVPIIPVCVSTTSN--KINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIM 225


                 ....
gi 446539250 234 ASQL 237
Cdd:PRK15018 226 EQKI 229
LPLAT_ACT14924-like cd07986
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 60-228 1.15e-14

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Pectobacterium carotovorum subsp. carotovorum PC1 locus ACT14924 putative acyltransferase, and similar proteins.


Pssm-ID: 153248 [Multi-domain]  Cd Length: 210  Bit Score: 70.35  E-value: 1.15e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIG----FVSKAEIKKFPvvptwmELMNCVFMV-----RNDRRQ 130
Cdd:cd07986   10 VDVSGLENIPKDGPVVIVANHPFGILDGLILADLLGSVRpdvrILANQLLSKIP------ELRDLFIPVdplegRAALAK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 131 SLQAIKDGIELLKNGHSIVIFPEGT----RSKGGEI--GEFKAGSFHLAVKSGVAILPVTLDGT-----YKM-------- 191
Cdd:cd07986   84 NRESLREALRHLKNGGALIIFPAGRvstaSPPFGRVsdRPWNPFVARLARKAKAPVVPVYFSGRnsrlfYLAglihptlr 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 446539250 192 -----FEANGNRMKPAHatVTISKPITSEEYANM-DIKELTKH 228
Cdd:cd07986  164 tlllpRELLNKRGKTIR--IRVGRPIPPEELARFeDAEELADF 204
PRK06814 PRK06814
acyl-[ACP]--phospholipid O-acyltransferase;
47-212 2.25e-14

acyl-[ACP]--phospholipid O-acyltransferase;


Pssm-ID: 235865 [Multi-domain]  Cd Length: 1140  Bit Score: 71.92  E-value: 2.25e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250   47 WFGKKMVRVaggaiEVNGLENVPK-DKPVLVVSNHQSNMDIPVLLGYL-NKPIGFVSKAEIKKFPVVPTwmelmncVFMV 124
Cdd:PRK06814  433 ILFRAFYRV-----EVKGLENLQKaGKKAVIAANHVSFLDGPLLAAYLpEEPTFAIDTDIAKAWWVKPF-------LKLA 500

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  125 RN---DRRQSLqAIKDGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDGT-YKMFEANGNRMK 200
Cdd:PRK06814  501 KAlpvDPTNPM-ATRTLIKEVQKGEKLVIFPEGRITVTGSLMKIYDGPGMIADKAGAMVVPVRIDGLqFTHFSRLKNQVR 579

                         170
                  ....*....|....*
gi 446539250  201 PA---HATVTISKPI 212
Cdd:PRK06814  580 RKwfpKVTVTILPPV 594
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 49-186 3.85e-13

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 64.93  E-value: 3.85e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  49 GKKMVRVAGGAIEVnglENVPKDKPVLVVSNHQSNMDIPVLLGY---LNKPIGFVSKAEIKKFPVVPtWMELMNCVFMvr 125
Cdd:cd07988    1 ARLLLRLSGWRIEG---EPPNKPKFVVIGAPHTSNWDFVLGLLAafaLGLKISFLGKHSLFKPPLGP-FMRWLGGIPV-- 74

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446539250 126 nDRRQS---LQAIKDGIellkNGHS---IVIFPEGTRSKGGEigeFKAGSFHLAVKSGVAILPVTLD 186
Cdd:cd07988   75 -DRSRAgglVEQVVEEF----RRREefvLAIAPEGTRSKVDK---WKTGFYHIARGAGVPILLVYLD 133
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
 60-156 2.36e-12

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 63.41  E-value: 2.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVL--LGYLNKPIG---FVSKAEIKKFPVVPTWMELMNCVFMVRNDRRQsLQA 134
Cdd:cd07990   12 VVVYGDEPKLPKERALIISNHRSEVDWLVLwmLADRFGRLGrlkIVLKDSLKYPPLGGWGWQLGEFIFLKRKWEKD-EKT 90

                         90       100
                 ....*....|....*....|....*
gi 446539250 135 IKDGIELLKNGH---SIVIFPEGTR 156
Cdd:cd07990   91 IKRQLKRLKDSPepfWLLIFPEGTR 115
LPLAT_MGAT-like cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; ...
 60-183 6.15e-10

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.


Pssm-ID: 153249 [Multi-domain]  Cd Length: 212  Bit Score: 57.30  E-value: 6.15e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVPKDKPVLVVSNHqsnmdipvllGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVRNDRR--QSLQAI-- 135
Cdd:cd07987    8 YEVRGLENIPDEGPALLVHPH----------GGLPIDGALLAAAFLLLFPGRLPRALADHFLFPLPGLRDllRRLGAVpg 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446539250 136 --KDGIELLKNGHSIVIFPEGTR----SKGGE---IGEFKAGSFHLAVKSGVAILPV 183
Cdd:cd07987   78 srENCVRLLREGELVLIFPGGARealkSKREEyylLWKKRKGFARLALRAGAPIVPV 134
LPLAT_DUF374-like cd07983
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; ...
 128-184 1.30e-06

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are the uncharacterized DUF374 phospholipid/glycerol acyltransferases and similar proteins.


Pssm-ID: 153245 [Multi-domain]  Cd Length: 189  Bit Score: 47.21  E-value: 1.30e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446539250 128 RRQSLQAIKDGIELLKNGHSIVIFPEGTRskgGEIGEFKAGSFHLAVKSGVAILPVT 184
Cdd:cd07983   80 SRGGAAALREMLRALKDGYNIAITPDGPR---GPRYKVKPGVILLARKSGAPIVPVA 133
LPLAT_DHAPAT-like cd07993
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ...
 68-185 1.69e-06

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.


Pssm-ID: 153255 [Multi-domain]  Cd Length: 205  Bit Score: 47.18  E-value: 1.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  68 VPKDKPVLVVSNHQSNMD---IPVLLGYLNKPIGFVSKAEIKKFPVVPTWMELMNCVFMVR---NDR--RQSLQAIkdGI 139
Cdd:cd07993   18 AQEGHPVVLLPTHRSYLDfllLSFILFSLGLPLPHIAAGENLNIPILGTLLRRLGAFFIRRsfgKDPlyRAVLQEY--VQ 95

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446539250 140 ELLKNGHSIVIFPEGTRSKGGEIGEFKAG-------SFHLAVKSGVAILPVTL 185
Cdd:cd07993   96 ELLKNGQPLEFFIEGTRSRTGKLLPPKLGllsvvveAYLKGSVPDVLIVPVSI 148
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 60-226 2.02e-06

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 46.82  E-value: 2.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVP----KDKPVLVVSNHQSNMDI-PVLLGYLNKPIGFVskAEIKKFPVVPTWMELMNCVFMVRN-DRRQSLQ 133
Cdd:cd07984    4 VEREGLEHLEaalaKGKGVILLTAHFGNWELaGLALALLGYPVTVV--YRPLKNPLLDRLITRGRERFGARLiPRGGGLR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250 134 AIkdgIELLKNGHSIVIFP-EGTRSKGGEIGEF---KA----GSFHLAVKSGVAILPVTldgtykmfeanGNRMKPAHAT 205
Cdd:cd07984   82 EL---IRALKKGEIVGILPdQDPGRKGGVFVPFfgrPAatptGPARLALKTGAPVVPAF-----------AYRLPGGGYR 147

                        170       180
                 ....*....|....*....|.
gi 446539250 206 VTISKPItsEEYANMDIKELT 226
Cdd:cd07984  148 IEFEPPL--ENPPSEDVEEDT 166
PRK08043 PRK08043
bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase;
60-187 1.52e-05

bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase;


Pssm-ID: 181207 [Multi-domain]  Cd Length: 718  Bit Score: 45.47  E-value: 1.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLnkPIGfvskaeikkfPVVPTWMELMNCVFM---------VRNDRRQ 130
Cdd:PRK08043  16 VRVTGDTQALKGERVLITPNHVSFLDGILLALFL--PVR----------PVFAVYTSISQQWYMrwlkpyidfVPLDPTK 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446539250 131 SLqAIKDGIELLKNGHSIVIFPEGTRSKGGEIGEFKAGSFHLAVKSGVAILPVTLDG 187
Cdd:PRK08043  84 PM-AIKHLVRLVEQGRPVVIFPEGRITVTGSLMKIYDGAGFVAAKSGATVIPVRIEG 139
PRK14014 PRK14014
putative acyltransferase; Provisional
 60-156 1.40e-04

putative acyltransferase; Provisional


Pssm-ID: 237584 [Multi-domain]  Cd Length: 301  Bit Score: 42.15  E-value: 1.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446539250  60 IEVNGLENVPKDKPVLVVSNHQSNMDIPVLLGYLNKPIGFV-----------------------------SKAEIKKFPv 110
Cdd:PRK14014  75 WDVEGLEGLSKKGWYLVISNHQSWVDILVLQYVFNRRIPMLkfflkqeliwvpflglawwaldfpfmkrySKAYLAKNP- 153

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 446539250 111 vptwmELmncvfmvrndRRQSLQAIKDGIELLKN-GHSIVIFPEGTR 156
Cdd:PRK14014 154 -----EL----------KGKDLETTRRACEKFKRmPTTIVNFVEGTR 185
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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