NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|446540130|ref|WP_000617476|]
View 

N-acetyltransferase [Escherichia coli]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10793418)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK10562 PRK10562
putative acetyltransferase; Provisional
 1-145 6.42e-94

putative acetyltransferase; Provisional


:

Pssm-ID: 236715 [Multi-domain]  Cd Length: 145  Bit Score: 267.70  E-value: 6.42e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   1 MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAYLANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKA 80
Cdd:PRK10562   1 MIREYQPSDLPAILQLWLESTIWAHPFIKEQYWRESAPLVRDVYLPAAQTWVWEEDGKLLGFVSVLEGRFVGALFVAPKA 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446540130  81 VRRGIGKALMQYVQQRYPHLMLEVYQKNQLAIDFYRAQGFHIVDCAWQDETQLPTWIMSWPVVQT 145
Cdd:PRK10562  81 VRRGIGKALMQHVQQRYPHLSLEVYQKNQRAVNFYHAQGFRIVDSAWQEETQHPTWIMSWQADQT 145
 
Name Accession Description Interval E-value
PRK10562 PRK10562
putative acetyltransferase; Provisional
 1-145 6.42e-94

putative acetyltransferase; Provisional


Pssm-ID: 236715 [Multi-domain]  Cd Length: 145  Bit Score: 267.70  E-value: 6.42e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   1 MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAYLANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKA 80
Cdd:PRK10562   1 MIREYQPSDLPAILQLWLESTIWAHPFIKEQYWRESAPLVRDVYLPAAQTWVWEEDGKLLGFVSVLEGRFVGALFVAPKA 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446540130  81 VRRGIGKALMQYVQQRYPHLMLEVYQKNQLAIDFYRAQGFHIVDCAWQDETQLPTWIMSWPVVQT 145
Cdd:PRK10562  81 VRRGIGKALMQHVQQRYPHLSLEVYQKNQRAVNFYHAQGFRIVDSAWQEETQHPTWIMSWQADQT 145
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 1-124 1.02e-16

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 71.18  E-value: 1.02e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   1 MIREAQRSELPAILELWLESttwghpfikanywrdciplvrDAYLANAQNWVWEEDGKLLGFVSI--MEGRF--LAAMFV 76
Cdd:COG1246    2 TIRPATPDDVPAILELIRPY---------------------ALEEEIGEFWVAEEDGEIVGCAALhpLDEDLaeLRSLAV 60

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446540130  77 APKAVRRGIGKALMQYV-----QQRYPHLMLEVYQKnqlAIDFYRAQGFHIVD 124
Cdd:COG1246   61 HPDYRGRGIGRRLLEALlaearELGLKRLFLLTTSA---AIHFYEKLGFEEID 110
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 10-120 2.90e-14

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 64.46  E-value: 2.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   10 LPAILELWLESTTWGHPFIKANYWRDCIPLVRDAYlanaqnWVWEEDGKLLGFVSIMEGR------FLAAMFVAPKAVRR 83
Cdd:pfam00583   1 LEALYELLSEEFPEPWPDEPLDLLEDWDEDASEGF------FVAEEDGELVGFASLSIIDdeppvgEIEGLAVAPEYRGK 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 446540130   84 GIGKALMQYV-----QQRYPHLMLEVYQKNQLAIDFYRAQGF 120
Cdd:pfam00583  75 GIGTALLQALlewarERGCERIFLEVAADNLAAIALYEKLGF 116
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 51-103 4.41e-07

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 44.57  E-value: 4.41e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446540130  51 WVWEEDGKLLGFVSIMEGR------FLAAMFVAPKAVRRGIGKALMQYV-----QQRYPHLMLE 103
Cdd:cd04301    2 LVAEDDGEIVGFASLSPDGsggdtaYIGDLAVLPEYRGKGIGSALLEAAeeearERGAKRLRLE 65
 
Name Accession Description Interval E-value
PRK10562 PRK10562
putative acetyltransferase; Provisional
 1-145 6.42e-94

putative acetyltransferase; Provisional


Pssm-ID: 236715 [Multi-domain]  Cd Length: 145  Bit Score: 267.70  E-value: 6.42e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   1 MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAYLANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKA 80
Cdd:PRK10562   1 MIREYQPSDLPAILQLWLESTIWAHPFIKEQYWRESAPLVRDVYLPAAQTWVWEEDGKLLGFVSVLEGRFVGALFVAPKA 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446540130  81 VRRGIGKALMQYVQQRYPHLMLEVYQKNQLAIDFYRAQGFHIVDCAWQDETQLPTWIMSWPVVQT 145
Cdd:PRK10562  81 VRRGIGKALMQHVQQRYPHLSLEVYQKNQRAVNFYHAQGFRIVDSAWQEETQHPTWIMSWQADQT 145
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 1-124 1.02e-16

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 71.18  E-value: 1.02e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   1 MIREAQRSELPAILELWLESttwghpfikanywrdciplvrDAYLANAQNWVWEEDGKLLGFVSI--MEGRF--LAAMFV 76
Cdd:COG1246    2 TIRPATPDDVPAILELIRPY---------------------ALEEEIGEFWVAEEDGEIVGCAALhpLDEDLaeLRSLAV 60

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446540130  77 APKAVRRGIGKALMQYV-----QQRYPHLMLEVYQKnqlAIDFYRAQGFHIVD 124
Cdd:COG1246   61 HPDYRGRGIGRRLLEALlaearELGLKRLFLLTTSA---AIHFYEKLGFEEID 110
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-124 2.35e-16

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 71.18  E-value: 2.35e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   1 MIREAQRSELPAILELWLESTTWGHpfikANYWRDCIPL-VRDAYLANAQN-----WVWEEDGKLLGFVSIMEGR----- 69
Cdd:COG1247    3 TIRPATPEDAPAIAAIYNEAIAEGT----ATFETEPPSEeEREAWFAAILApgrpvLVAEEDGEVVGFASLGPFRprpay 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446540130  70 ---FLAAMFVAPKAVRRGIGKALMQYVQQR-----YPHLMLEVYQKNQLAIDFYRAQGFHIVD 124
Cdd:COG1247   79 rgtAEESIYVDPDARGRGIGRALLEALIERarargYRRLVAVVLADNEASIALYEKLGFEEVG 141
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 10-120 2.90e-14

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 64.46  E-value: 2.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   10 LPAILELWLESTTWGHPFIKANYWRDCIPLVRDAYlanaqnWVWEEDGKLLGFVSIMEGR------FLAAMFVAPKAVRR 83
Cdd:pfam00583   1 LEALYELLSEEFPEPWPDEPLDLLEDWDEDASEGF------FVAEEDGELVGFASLSIIDdeppvgEIEGLAVAPEYRGK 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 446540130   84 GIGKALMQYV-----QQRYPHLMLEVYQKNQLAIDFYRAQGF 120
Cdd:pfam00583  75 GIGTALLQALlewarERGCERIFLEVAADNLAAIALYEKLGF 116
PRK10514 PRK10514
putative acetyltransferase; Provisional
 2-120 6.49e-14

putative acetyltransferase; Provisional


Pssm-ID: 182510 [Multi-domain]  Cd Length: 145  Bit Score: 64.25  E-value: 6.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   2 IREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRdAYLANAQNWVW--EEDgKLLGFVSIMEGRfLAAMFVAPK 79
Cdd:PRK10514   4 IRRSRHEEGERLVAIWRRSVDATHDFLSAEDRAEIEELVR-SFLPEAPLWVAvdERD-QPVGFMLLSGGH-MEALFVDPD 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 446540130  80 AVRRGIGKALMQYVQQRYPHLMLEVYQKNQLAIDFYRAQGF 120
Cdd:PRK10514  81 VRGCGVGRMLVEHALSLHPELTTDVNEQNEQAVGFYKKMGF 121
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 47-124 1.50e-13

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 63.06  E-value: 1.50e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   47 NAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRY----PHLM-LEVYQKNQlAIDFYRAQGFH 121
Cdd:pfam13673  30 EYFFFVAFEGGQIVGVIALRDRGHISLLFVDPDYQGQGIGKALLEAVEDYAekdgIKLSeLTVNASPY-AVPFYEKLGFR 108


                  ...
gi 446540130  122 IVD 124
Cdd:pfam13673 109 ATG 111
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
2-124 3.84e-13

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 62.41  E-value: 3.84e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   2 IREAQRSELPAILELWLESttWGHPfikanYWRDCIPLVRDAyLANAQNWVWEEDGKLLGFVSIMEGR--------FLAA 73
Cdd:COG3153    1 IRPATPEDAEAIAALLRAA--FGPG-----REAELVDRLRED-PAAGLSLVAEDDGEIVGHVALSPVDidgegpalLLGP 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446540130  74 MFVAPKAVRRGIGKALMQYV-----QQRYPHLMLEVyqkNQLAIDFYRAQGFHIVD 124
Cdd:COG3153   73 LAVDPEYRGQGIGRALMRAAleaarERGARAVVLLG---DPSLLPFYERFGFRPAG 125
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 61-124 6.06e-13

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 60.44  E-value: 6.06e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446540130  61 GFVSIMEGR-----FLAAMFVAPKAVRRGIGKALMQYVQQR-----YPHLMLEVYQKNQLAIDFYRAQGFHIVD 124
Cdd:COG0456    1 GFALLGLVDggdeaEIEDLAVDPEYRGRGIGRALLEAALERarergARRLRLEVREDNEAAIALYEKLGFEEVG 74
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 51-122 1.35e-11

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 56.69  E-value: 1.35e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446540130   51 WVWEEDGKLLGFVSIM-----EGRFLAAMFVAPKAVRRGIGKALMQYVQQ--RYPHLMLEVYQKNQLAIDFYRAQGFHI 122
Cdd:pfam13508   6 FVAEDDGKIVGFAALLplddeGALAELRLAVHPEYRGQGIGRALLEAAEAaaKEGGIKLLELETTNRAAAFYEKLGFEE 84
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 54-124 8.55e-10

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 53.52  E-value: 8.55e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130  54 EEDGKLLGFVSIM----EGRFLAAMFVAPKAVRRGIGKALMQYV-----QQRYPHLMLEVYQKNQLAIDFYRAQGFHIVD 124
Cdd:COG0454   40 DDKGEPIGFAGLRrlddKVLELKRLYVLPEYRGKGIGKALLEALlewarERGCTALELDTLDGNPAAIRFYERLGFKEIE 119
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 51-103 4.41e-07

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 44.57  E-value: 4.41e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446540130  51 WVWEEDGKLLGFVSIMEGR------FLAAMFVAPKAVRRGIGKALMQYV-----QQRYPHLMLE 103
Cdd:cd04301    2 LVAEDDGEIVGFASLSPDGsggdtaYIGDLAVLPEYRGKGIGSALLEAAeeearERGAKRLRLE 65
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
41-123 3.30e-05

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 40.94  E-value: 3.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130  41 RDAYLANAQNWVWEEDGKLLGFVSIME--------GRflaaMFVAPKAVRRGIGKALMQYV-----QQRYPHLMLEVyqk 107
Cdd:COG2153   27 LDGKDEDARHLLAYDDGELVATARLLPpgdgeakiGR----VAVLPEYRGQGLGRALMEAAieearERGARRIVLSA--- 99

                         90
                 ....*....|....*..
gi 446540130 108 nQL-AIDFYRAQGFHIV 123
Cdd:COG2153  100 -QAhAVGFYEKLGFVPV 115
PRK03624 PRK03624
putative acetyltransferase; Provisional
 2-125 5.06e-05

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 40.68  E-value: 5.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   2 IREAQRSELPAILELWlESTTWGHPfikanyWRDciPLVRDAYLANAQN---WVWEEDGKLLGfvSIMEG----R----F 70
Cdd:PRK03624   5 IRVFRQADFEAVIALW-ERCDLTRP------WND--PEMDIERKLNHDPslfLVAEVGGEVVG--TVMGGydghRgwayY 73

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130  71 LAamfVAPKAVRRGIGKALMQYVQQRY-----PHLMLEVYQKNQLAIDFYRAQGFHIVDC 125
Cdd:PRK03624  74 LA---VHPDFRGRGIGRALVARLEKKLiargcPKINLQVREDNDAVLGFYEALGYEEQDR 130
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
71-120 1.05e-04

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 38.74  E-value: 1.05e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446540130  71 LAAMFVAPKAVRRGIGKALMQYV-----QQRYPHLMLEVYQKNQLAIDFYRAQGF 120
Cdd:COG3393   18 ISGVYTHPEYRGRGLASALVAALarealARGARTPFLYVDADNPAARRLYERLGF 72
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 2-140 5.77e-04

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 38.06  E-value: 5.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130   2 IREAQRSELPAILELWLESTTW----GHPFIKANYWRDCIPLVRDAYLANAQNWV--WEEDGKLLGFVSIME-----GRF 70
Cdd:COG1670   10 LRPLRPEDAEALAELLNDPEVArylpGPPYSLEEARAWLERLLADWADGGALPFAieDKEDGELIGVVGLYDidranRSA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130  71 LAAMFVAPKAVRRGIGKALMQYV------QQRYPHLMLEVYQKNQLAIDFYRAQGFHIV----DCAWQDETQLPTWIMSW 140
Cdd:COG1670   90 EIGYWLAPAYWGKGYATEALRALldyafeELGLHRVEAEVDPDNTASIRVLEKLGFRLEgtlrDALVIDGRYRDHVLYSL 169
PRK09831 PRK09831
GNAT family N-acetyltransferase;
45-123 7.26e-04

GNAT family N-acetyltransferase;


Pssm-ID: 182099  Cd Length: 147  Bit Score: 37.63  E-value: 7.26e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446540130  45 LANAQNWVWEEDGKLLGFVSIMeGRFLAAMFVAPKAVRRGIGKALMQYVQQRYPHLMLEVyqkNQLAIDFYRAQGFHIV 123
Cdd:PRK09831  50 LAKSQVRVAVINAQPVGFITCI-EHYIDMLFVDPEYTRRGVASALLKPLIKSESELTVDA---SITAKPFFERYGFQTV 124
Acetyltransf_9 pfam13527
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 2-120 9.17e-04

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 404421 [Multi-domain]  Cd Length: 124  Bit Score: 36.78  E-value: 9.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446540130    2 IREAQRSELPAILELWLESTTWGHPFIKANYWRDciplvrdaYLANAQNWVWEEDGKLLGF-------VSIMEGRFLAAM 74
Cdd:pfam13527   1 IRPLTEDEFDEVLRLLEYAFQDEDSPELREYFRP--------LLEEGRVLGAFDDGELVSTlalypfeLNVPGKTLPAAG 72

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 446540130   75 F----VAPKAVRRGIGKALMQyvqqrypHLMLEVYQKNQL-------AIDFYRAQGF 120
Cdd:pfam13527  73 ItgvaTYPEYRGRGVMSRLLR-------RSLEEMRERGVPlsflypsSYPIYRRFGY 122
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 76-124 4.24e-03

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 35.29  E-value: 4.24e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446540130  76 VAPKAVRRGIGKALMQYVQQRYPH-----LMLEVYQKNQLAIDFYRAQGFHIVD 124
Cdd:PRK09491  71 VDPDYQRQGLGRALLEHLIDELEKrgvatLWLEVRASNAAAIALYESLGFNEVT 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH