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Conserved domains on  [gi|446546139|ref|WP_000623485|]
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MULTISPECIES: CrcB family protein [Staphylococcus]

Protein Classification

fluoride efflux transporter FluC( domain architecture ID 10000802)

fluoride efflux transporter FluC is fluoride-specific ion channel which Important for reducing fluoride concentration in the cell to reduce its toxicity

Gene Ontology:  GO:0022857|GO:0016020|GO:0055085
PubMed:  33492991|25156118
TCDB:  1.A.43

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 1-117 3.16e-25

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


:

Pssm-ID: 440009  Cd Length: 125  Bit Score: 91.70  E-value: 3.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP----AFFVTGFLGGLTTF 76
Cdd:COG0239    1 MKTLLLVALGGALGALLRYLLSLLLPRLFGSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSpelrLLLGTGFLGGFTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 446546139  77 STLAKElTLMMMPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:COG0239   81 STFSLE-TVRLLERGRYLLALLYVLLSVVLGLLAAALGLAL 120
 
Name Accession Description Interval E-value
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 1-117 3.16e-25

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 91.70  E-value: 3.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP----AFFVTGFLGGLTTF 76
Cdd:COG0239    1 MKTLLLVALGGALGALLRYLLSLLLPRLFGSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSpelrLLLGTGFLGGFTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 446546139  77 STLAKElTLMMMPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:COG0239   81 STFSLE-TVRLLERGRYLLALLYVLLSVVLGLLAAALGLAL 120
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 6-113 4.92e-18

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 72.89  E-value: 4.92e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139    6 LVMIGGGLGAIARSAVTdYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFSTLAKE 82
Cdd:pfam02537   1 LVALGGALGALLRYLLS-LLNPRLAGGFPLGTLAVNVLGSFLLGLLAGLLLERGHSPElrlLLGTGFCGGLTTFSTFSLE 79

                          90       100       110
                  ....*....|....*....|....*....|.
gi 446546139   83 lTLMMMPKFNINLFLNYSLLQFIIGFIACYI 113
Cdd:pfam02537  80 -TLTLLRAGQYLLALLYVLLSVVLGLAAVVL 109
PRK14216 PRK14216
fluoride efflux transporter CrcB;
7-114 9.80e-14

fluoride efflux transporter CrcB;


Pssm-ID: 184572  Cd Length: 132  Bit Score: 62.55  E-value: 9.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   7 VMIGGGLGAIARSAVTDYFNHKfTSKLPIATLIVNLVGSFLIGLTIG-----LSISiSWFPAFFVTGFLGGLTTFSTLAK 81
Cdd:PRK14216  12 VFAGGALGTLARAALSELAAPD-PARWPWPTFTVNVVGAFLLGYFTTrllerLPLS-SYRRPLLGTGLCGGLTTFSTMQV 89

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446546139  82 ElTLMMMPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14216  90 E-TIRMIEHGHWGLAAGYTAASIAAGLLAVHLA 121
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 5-117 9.46e-08

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 46.61  E-value: 9.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139    5 ILVMIGGGLGAIARSAVTDYFNHK-FTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFSTLA 80
Cdd:TIGR00494   1 LAIFLGGGPGALLRYLLGIFISAGlFGNSLPLGTLTVNIIGCFGIGFVTLFTQPAVISPDlklLIGTGFLGGFTTFSTFS 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 446546139   81 KELTLMMMPKFNINLFLnYSLLQFIIGFIACYIGYHI 117
Cdd:TIGR00494  81 LETTSLLQEGQLGEAVL-YILGTLGGGLIGVALGWLL 116
 
Name Accession Description Interval E-value
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 1-117 3.16e-25

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 91.70  E-value: 3.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP----AFFVTGFLGGLTTF 76
Cdd:COG0239    1 MKTLLLVALGGALGALLRYLLSLLLPRLFGSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSpelrLLLGTGFLGGFTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 446546139  77 STLAKElTLMMMPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:COG0239   81 STFSLE-TVRLLERGRYLLALLYVLLSVVLGLLAAALGLAL 120
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 6-113 4.92e-18

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 72.89  E-value: 4.92e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139    6 LVMIGGGLGAIARSAVTdYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFSTLAKE 82
Cdd:pfam02537   1 LVALGGALGALLRYLLS-LLNPRLAGGFPLGTLAVNVLGSFLLGLLAGLLLERGHSPElrlLLGTGFCGGLTTFSTFSLE 79

                          90       100       110
                  ....*....|....*....|....*....|.
gi 446546139   83 lTLMMMPKFNINLFLNYSLLQFIIGFIACYI 113
Cdd:pfam02537  80 -TLTLLRAGQYLLALLYVLLSVVLGLAAVVL 109
PRK14216 PRK14216
fluoride efflux transporter CrcB;
7-114 9.80e-14

fluoride efflux transporter CrcB;


Pssm-ID: 184572  Cd Length: 132  Bit Score: 62.55  E-value: 9.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   7 VMIGGGLGAIARSAVTDYFNHKfTSKLPIATLIVNLVGSFLIGLTIG-----LSISiSWFPAFFVTGFLGGLTTFSTLAK 81
Cdd:PRK14216  12 VFAGGALGTLARAALSELAAPD-PARWPWPTFTVNVVGAFLLGYFTTrllerLPLS-SYRRPLLGTGLCGGLTTFSTMQV 89

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446546139  82 ElTLMMMPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14216  90 E-TIRMIEHGHWGLAAGYTAASIAAGLLAVHLA 121
PRK14205 PRK14205
fluoride efflux transporter CrcB;
1-114 1.45e-13

fluoride efflux transporter CrcB;


Pssm-ID: 172693  Cd Length: 118  Bit Score: 61.74  E-value: 1.45e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWfPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14205   1 MIEALLVATGGFFGAITRFAISNWFKKRNKTSFPIATFLINITGAFLLGYIIGNGVTTGW-QLLLGTGFMGAFTTFSTFK 79

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446546139  81 KElTLMMMPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14205  80 LE-SVQLLNRKNFSTFLLYLSATYIVGILFAFLG 112
PRK14220 PRK14220
fluoride efflux transporter CrcB;
2-117 7.41e-13

fluoride efflux transporter CrcB;


Pssm-ID: 237641  Cd Length: 120  Bit Score: 60.17  E-value: 7.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   2 ISIILVMIGGGLGAIARSAVTDYFNHKFT--SKLPIATLIVNLVGSFLIGLTIGLSISISWFpAFFVTGFLGGLTTFSTL 79
Cdd:PRK14220   1 MTILLAGFGASIGAMLRYAITNYGKKHWEqfSNLPTPTLLINLTGAFILGLIFGRKFNPFIY-ALLGTGVLGGYTTFSTL 79

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 446546139  80 AKELTLMMMPKfNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14220  80 NTELVSLYKSK-NYRVLKLYALLSYLGGLILVFCGYYL 116
PRK14195 PRK14195
fluoride efflux transporter CrcB;
1-117 8.01e-13

fluoride efflux transporter CrcB;


Pssm-ID: 184563  Cd Length: 125  Bit Score: 60.05  E-value: 8.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLsISISWFPA-----FFVTGFLGGLTT 75
Cdd:PRK14195   1 MINILLVAAGGALGSVARYLVGVGALRLMGPAFPWGTLAVNVTGSFLIGVLAGL-LAHRWNASqewrlFLIVGVLGGFTT 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446546139  76 FSTLAKElTLMMMPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14195  80 FSAFSLD-AALLIERGAYGAAAAYIAASVVLSVAALFAGLAI 120
PRK14196 PRK14196
fluoride efflux transporter CrcB;
1-88 2.19e-12

fluoride efflux transporter CrcB;


Pssm-ID: 184564  Cd Length: 127  Bit Score: 59.08  E-value: 2.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSkLPIATLIVNLVGSFLIGLTIGL-----SISISWfPAFFVTGFLGGLTT 75
Cdd:PRK14196   2 LQSLLAVFIGAGLGALLRWLLGLRLNPLFPA-LPLGTLAANLIGGYIIGVAVAWfarmpGLDPEW-RLLIITGFCGGLTT 79

                         90
                 ....*....|...
gi 446546139  76 FSTLAKELTLMMM 88
Cdd:PRK14196  80 FSTFSAEVVTLLQ 92
PRK14212 PRK14212
fluoride efflux transporter CrcB;
1-82 2.87e-11

fluoride efflux transporter CrcB;


Pssm-ID: 184569  Cd Length: 128  Bit Score: 56.36  E-value: 2.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14212   1 MGEILLLAAGGALGAVSRYGLNNLTVKLLGDSFPYGTLIVNCLGCFVLGFLMQWGFSSDSHNThlklMLTAGFLGAFTTF 80


                 ....*.
gi 446546139  77 STLAKE 82
Cdd:PRK14212  81 STFSYE 86
PRK14214 PRK14214
fluoride efflux transporter CrcB;
1-114 1.16e-10

fluoride efflux transporter CrcB;


Pssm-ID: 184571  Cd Length: 118  Bit Score: 54.49  E-value: 1.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWfPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14214   2 LVNFLLVGFGAALGAMLRYGISVLVKSKWKTNFPYATFFINITGSFLLGFLVSSALGPVW-QLFLGTGFMGGYTTFSTFK 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446546139  81 KElTLMMMPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14214  81 VE-SMELKWKTNYRVLFSYLGCTYVFGLIAAFLG 113
PRK14211 PRK14211
fluoride efflux transporter CrcB;
2-117 2.07e-10

fluoride efflux transporter CrcB;


Pssm-ID: 172699  Cd Length: 114  Bit Score: 53.78  E-value: 2.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   2 ISIILVMIGGGLGAIARSAVTDYFNHkfTSKLPIATLIVNLVGSFLIGLTIGLSISISWFpAFFVTGFLGGLTTFSTLAK 81
Cdd:PRK14211   1 MTVLLVALGGALGATTRYLTGRYVDS--YRSFPVATFLVNVAGCLILGLLSGASLSTQTF-ALLGTGFCGGLTTYSTFAV 77

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446546139  82 ElTLMMMPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14211  78 E-SVGLLRIRQALLSVVYIVASVAAGLAAAWLGFRL 112
PRK14208 PRK14208
fluoride efflux transporter CrcB;
1-101 4.75e-10

fluoride efflux transporter CrcB;


Pssm-ID: 172696  Cd Length: 126  Bit Score: 53.04  E-value: 4.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14208   1 MARLLLVCLGGALGSGARYLTSAWALRAFGPDFPRGTLLVNVSGSFLLAGIMTASLQSEAVPPdlrlFLAAGVMGGFTTY 80

                         90       100
                 ....*....|....*....|....*
gi 446546139  77 STLAKElTLMMMPKFNINLFLNYSL 101
Cdd:PRK14208  81 SSFNYE-TLALLEQGRLAAAAAYLL 104
PRK14202 PRK14202
fluoride efflux transporter CrcB;
1-78 7.80e-10

fluoride efflux transporter CrcB;


Pssm-ID: 172690  Cd Length: 128  Bit Score: 52.41  E-value: 7.80e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHkFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14202   5 FSAVLLVGAGGFLGSVARYLVALALSF-IGTGFPFATFTVNLLGSFLIGFISELALSTTLVSPearlLLVTGFCGGFTTF 83


                 ..
gi 446546139  77 ST 78
Cdd:PRK14202  84 SS 85
PRK14201 PRK14201
fluoride efflux transporter CrcB;
7-114 3.91e-09

fluoride efflux transporter CrcB;


Pssm-ID: 184566  Cd Length: 121  Bit Score: 50.47  E-value: 3.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   7 VMIGGGLGAIARSAVTdYFNHKFTskLPIATLIVNLVGSFLIGLTIGLSISI----SWFPAFFVTGFLGGLTTFSTLAKE 82
Cdd:PRK14201   6 IFIGGALGALLRYLLS-FLNTDGG--FPIGTLIANLTGAFLMGLLTALTIAFfsnhPTLKKAITTGFLGALTTFSTFQFE 82

                         90       100       110
                 ....*....|....*....|....*....|..
gi 446546139  83 LtLMMMPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14201  83 L-IHMFDHQQFITLLLYAVTSYIFGILLCYVG 113
PRK14228 PRK14228
fluoride efflux transporter CrcB;
7-78 1.01e-08

fluoride efflux transporter CrcB;


Pssm-ID: 237643  Cd Length: 122  Bit Score: 49.36  E-value: 1.01e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446546139   7 VMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISwfPAFFV-TGFLGGLTTFST 78
Cdd:PRK14228  10 VMLIGGIGSVLRFLVDRTVARRLARTFPYGTLAVNVSGAALLGFLAGLALPKD--AALLAgTAFVGAYTTFST 80
PRK14197 PRK14197
fluoride efflux transporter CrcB;
1-106 1.34e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172685  Cd Length: 124  Bit Score: 48.98  E-value: 1.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP---AFFVTGFLGGLTTFS 77
Cdd:PRK14197   1 MNNVLFVALGGSIGAVLRYLISIFMIQVFGSSFPFGTLLVNVLGSFLMGVIYALGQMSHVSPelkALIGVGLLGALTTFS 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446546139  78 TLAKELTLMMMP----KFNINLFLNYSLLQFII 106
Cdd:PRK14197  81 TFSNETLLLMQEgawlKAALNVVLNLSLCLFMV 113
PRK14199 PRK14199
fluoride efflux transporter CrcB;
1-115 3.63e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172687  Cd Length: 128  Bit Score: 48.23  E-value: 3.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14199   4 LILAIIVGLGGFIGASLRYLISIFAAKMFNGNFPYGTLIVNIVGALLIGFIMEFSMDTALISSnmklFLTTGIMGGLTTF 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 446546139  77 STLAKELTLMM------MPKFNINLFLNYSLLQFIIGFIACYIGY 115
Cdd:PRK14199  84 STFSYETINLItngnilLGIENIILNLGLSLLGVVIGQKLARILF 128
PRK14207 PRK14207
fluoride efflux transporter CrcB;
4-82 6.54e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172695  Cd Length: 123  Bit Score: 47.43  E-value: 6.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   4 IILVMIGGGLGAIARSAVTDYFnhKFTSKLPIATLIVNLVGSFLIG-----LTIGLSISISWfPAFFVTGFLGGLTTFST 78
Cdd:PRK14207   6 ALAVAIGGGLGALARYYISGLL--PVYKDFPVGTLLVNSIASFILGylyglLFWGFDVSPEW-RAFLGTGFCGGLSTFST 82


                 ....
gi 446546139  79 LAKE 82
Cdd:PRK14207  83 FSYE 86
PRK14229 PRK14229
fluoride efflux transporter CrcB;
4-117 7.77e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172717  Cd Length: 108  Bit Score: 46.75  E-value: 7.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   4 IILVMIGGGLGAIARSAVTDYFNHkftSKLPIATLIVNLVGSFLIGLTIGlSISISWFPAFFVTGFLGGLTTFSTLAKEL 83
Cdd:PRK14229   2 IVYLAIACGLGALVRYFFSRYNQA---SKLPLGTLIANLLGCFLIGVFYN-HVESKEVYAILATGFCGGLTTFSTLNDEL 77

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446546139  84 TLMMMPKfniNLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14229  78 QRLLSDK---KVFYSYLTLTYIGGLVAIFLGILL 108
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 5-117 9.46e-08

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 46.61  E-value: 9.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139    5 ILVMIGGGLGAIARSAVTDYFNHK-FTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFSTLA 80
Cdd:TIGR00494   1 LAIFLGGGPGALLRYLLGIFISAGlFGNSLPLGTLTVNIIGCFGIGFVTLFTQPAVISPDlklLIGTGFLGGFTTFSTFS 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 446546139   81 KELTLMMMPKFNINLFLnYSLLQFIIGFIACYIGYHI 117
Cdd:TIGR00494  81 LETTSLLQEGQLGEAVL-YILGTLGGGLIGVALGWLL 116
PRK14222 PRK14222
fluoride efflux transporter CrcB;
1-82 9.54e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172710  Cd Length: 124  Bit Score: 47.01  E-value: 9.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPAFF----VTGFLGGLTTF 76
Cdd:PRK14222   1 METLVYIALFGALGCLARYYLSGWVYALFGRAFPYGTLAVNVIGAFLIGLIMEFSLRSTLIPPTLriglTIGFLGGLTTF 80


                 ....*.
gi 446546139  77 STLAKE 82
Cdd:PRK14222  81 STFSYE 86
PRK14232 PRK14232
fluoride efflux transporter CrcB;
5-117 9.61e-08

fluoride efflux transporter CrcB;


Pssm-ID: 237644  Cd Length: 120  Bit Score: 46.70  E-value: 9.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   5 ILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISwFPAFFVTGFLGGLTTFSTLAKELT 84
Cdd:PRK14232   4 VFVGIGGAFGSLARYQLGKVISKKSKSTFPVGTFIINITGAILLGIVSSSNISKN-MYLLLGDGFLGAYTTFSTFMYEGF 82

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446546139  85 LMMMPKFNINLFLnYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14232  83 NLFQEKEKLNAFI-YILGSLIIGIIGYILGFWI 114
PRK14227 PRK14227
fluoride efflux transporter CrcB;
1-114 9.93e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172715  Cd Length: 124  Bit Score: 46.75  E-value: 9.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSIS-ISWFPA---FFVTGFLGGLTTF 76
Cdd:PRK14227   1 MMKYIVVAIGGSIGAILRYFTGVYSAKNLGLDFPYGTLIVNSVGSFILSFFMILFLEkLSLDPLwrlFVAVGFCGSFTTF 80

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 446546139  77 STLAKELTLMMMPKFNINLFLNYsLLQFIIGFIACYIG 114
Cdd:PRK14227  81 SSFTYETIALFQDGDYTKAMLNI-ILNNVLSITSAFSG 117
PRK14223 PRK14223
fluoride efflux transporter CrcB;
1-98 1.08e-07

fluoride efflux transporter CrcB;


Pssm-ID: 184576  Cd Length: 122  Bit Score: 46.60  E-value: 1.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFtsKLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFS 77
Cdd:PRK14223   1 MRELLLIGIGGFFGAILRYLISGIIPVKF--GIPTGTLIVNLIGSFILGFLLYSSLFGSISPEyrlFIITGFCGALTTFS 78

                         90       100
                 ....*....|....*....|.
gi 446546139  78 TLAKELTLMMMPKFNINLFLN 98
Cdd:PRK14223  79 TFSYETFSLLEEGLYIKALLN 99
PRK14234 PRK14234
fluoride efflux transporter CrcB;
1-114 1.08e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172722  Cd Length: 124  Bit Score: 46.69  E-value: 1.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIIL-VMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP----AFFVTGFLGGLTT 75
Cdd:PRK14234   1 MIRLILaVSAGGIAGTLLRFATGNWVSANWPRHFYAATLAVNIVGCLLIGLLYGLFLLRPEVPielrAGLIVGFLGGLTT 80

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 446546139  76 FSTLAKElTLMMMPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14234  81 FSSFSLD-TLRLLESGQVPLALGYAGISVFGGLLATWAG 118
PRK14209 PRK14209
fluoride efflux transporter CrcB;
3-80 1.53e-07

fluoride efflux transporter CrcB;


Pssm-ID: 237640  Cd Length: 124  Bit Score: 46.47  E-value: 1.53e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446546139   3 SIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIG-LTIGLSISISWFPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14209   4 SLLQVALGGALGASARYLTNVGSMRLFGPAFPVGTMIVNVVGSFLMGvLVVVLAHKGNRYAPFLMTGMLGGFTTFSAFS 82
PRK14206 PRK14206
fluoride efflux transporter CrcB;
5-86 1.58e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172694  Cd Length: 127  Bit Score: 46.34  E-value: 1.58e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   5 ILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLS-------ISISWfPAFFVTGFLGGLTTFS 77
Cdd:PRK14206   4 LWIALGSALGGTLRFWLSGLVAEATGGTFPWGTLVINVSGSFLIGFFATLTgpegrvfVGESW-RLFVMVGVCGGFTTFS 82

                         90
                 ....*....|
gi 446546139  78 TLA-KELTLM 86
Cdd:PRK14206  83 SFSlQTLNLA 92
PRK14233 PRK14233
fluoride efflux transporter CrcB;
5-88 5.57e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172721  Cd Length: 133  Bit Score: 44.87  E-value: 5.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   5 ILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLS------ISISWFPAFFVTGFLGGLTTFST 78
Cdd:PRK14233   7 ILVLVGGFIGGVMRFFLSGYVGRRIGETFPWGTFVVNVSGAFVIGTAAGLGarlggiFSTTIFHEFIMVGLLGGYTTVSS 86

                         90
                 ....*....|
gi 446546139  79 LAKELTLMMM 88
Cdd:PRK14233  87 FCLQSVNLML 96
ccrB PRK00134
fluoride efflux transporter family protein;
1-80 6.09e-07

fluoride efflux transporter family protein;


Pssm-ID: 234656  Cd Length: 104  Bit Score: 44.40  E-value: 6.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFnhkftSKLPIATLIVNLVGSFLIGltiglsisisWF--PAFFVTGFLGGLTTFST 78
Cdd:PRK00134   4 LPQGLLVGAGAALGACVRLALTSQL-----GDAPWPILLINVLGAFLMG----------WLrpNAFWGTGFLGGFTSFSA 68


                 ..
gi 446546139  79 LA 80
Cdd:PRK00134  69 FA 70
PRK14200 PRK14200
fluoride efflux transporter CrcB;
7-117 6.90e-07

fluoride efflux transporter CrcB;


Pssm-ID: 237638  Cd Length: 127  Bit Score: 44.79  E-value: 6.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   7 VMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTI-----GLSISISWFPAFFVtGFLGGLTTFSTLAK 81
Cdd:PRK14200  10 IALGGAFGACSRYLVSELCVVLLGRGFPYGTLTVNVVGSFIMGLLIaafenELLATEPWRQIIGL-GFLGALTTFSTFSM 88

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446546139  82 ELTLMMMPKFNINLFLNYsLLQFIIGFIACYIGYHI 117
Cdd:PRK14200  89 DNVLLMQQGAFFKMGLNV-LLNVVLSISAAWIGFQL 123
PRK14215 PRK14215
fluoride efflux transporter CrcB;
1-114 7.25e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172703  Cd Length: 126  Bit Score: 44.43  E-value: 7.25e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14215   1 MNNILAIAVGAAIGANLRYGIGLWAAQRWGTSWPYGTFIINLLGCLLIGLLLTLATTRLTLSEparlMLVTGLLGGFTTF 80

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 446546139  77 STLAKElTLMMMPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14215  81 STFGYE-SYSLLSSGNWLAAGGYVVGSVGGGLIAVIIG 117
PRK14198 PRK14198
fluoride efflux transporter CrcB;
5-87 1.00e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172686  Cd Length: 124  Bit Score: 44.35  E-value: 1.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   5 ILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGL-----SISISWfPAFFVTGFLGGLTTFSTL 79
Cdd:PRK14198   4 LLVFVGGGLGASLRHAVNMASARLLGTSFPYGTFIINVSGSLVMGLIAGYlafkgGAPQHW-RLFLMTGILGGYTTFSAF 82


                 ....*...
gi 446546139  80 AKELTLMM 87
Cdd:PRK14198  83 SLDAALLY 90
PRK14213 PRK14213
camphor resistance protein CrcB; Provisional
 2-90 1.78e-06

camphor resistance protein CrcB; Provisional


Pssm-ID: 184570  Cd Length: 118  Bit Score: 43.27  E-value: 1.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   2 ISIILVMIGGGLGAIARSAVTDYFNHKFTS-KLPIATLIVNLVGSFLIGLTIGLSISISWFPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14213   1 MTLAGIFIAGGIGAVLRFWLGNVITAKTKGlSLPIGIMTVNILGSFGLGIFTGLGVDNASVSIIIGTGFFGAFTTFSTFS 80

                         90
                 ....*....|
gi 446546139  81 KELTLMMMPK 90
Cdd:PRK14213  81 VEAVQLLMAK 90
PRK14217 PRK14217
fluoride efflux transporter CrcB;
5-98 1.82e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172705  Cd Length: 134  Bit Score: 43.84  E-value: 1.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   5 ILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIG----LTIGLSISISWFPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14217   7 LAVAIGGSLGAMSRYLVTIMAQNAWGIKFPYGTLLVNTLGSFLAGffliVLVGRFSAEESFRLFLFTGFLGAFTTFSSFA 86

                         90
                 ....*....|....*...
gi 446546139  81 KELTLMMMPKFNINLFLN 98
Cdd:PRK14217  87 AESLFMFEQGYWFKLITN 104
PRK14226 PRK14226
fluoride efflux transporter CrcB;
4-117 2.30e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172714  Cd Length: 130  Bit Score: 43.33  E-value: 2.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   4 IILVMIGGGLGAIARSAVTDYfNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP--------AFFVTGFLGGLTT 75
Cdd:PRK14226   5 LLLVGIGGGFGAMARFALTQA-TASISKQIPLGILLCNIIGSLIIGMMAAFLIETKLFNedvstyvrFLLVTGFLGGFTT 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446546139  76 FSTLAKELtLMMMPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14226  84 FSSFSLDI-LNLLQRGEIFIAIGYIMVSVLASLIAVILGFYI 124
PRK14218 PRK14218
fluoride efflux transporter CrcB;
3-82 5.49e-06

fluoride efflux transporter CrcB;


Pssm-ID: 184573  Cd Length: 133  Bit Score: 42.57  E-value: 5.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   3 SIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLT---IGLSISISW-FPAFFVTGFLGGLTTFST 78
Cdd:PRK14218   9 SLLLVMLGGAFGSGLRFVIGSCLLQRFGAGFPWGTLAVNLIGSFVAGFLliwLDKRGSAGWpWRMLLIVGLIGGLTTFSS 88


                 ....
gi 446546139  79 LAKE 82
Cdd:PRK14218  89 LMME 92
PRK14224 PRK14224
fluoride efflux transporter CrcB;
1-80 4.58e-05

fluoride efflux transporter CrcB;


Pssm-ID: 237642  Cd Length: 126  Bit Score: 39.76  E-value: 4.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   1 MISIILVMIGGGLGAIARSAVTDyfnhkfTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14224   8 IDKLFLIGAGGFLGAICRFLICE------LIEGQLGTLSVNVLGSFMLGMIMYDTEYIGFIGPkgrlAFGTGFLGAFTTF 81


                 ....
gi 446546139  77 STLA 80
Cdd:PRK14224  82 STFA 85
PRK14203 PRK14203
fluoride efflux transporter CrcB;
4-80 1.55e-04

fluoride efflux transporter CrcB;


Pssm-ID: 237639  Cd Length: 132  Bit Score: 38.64  E-value: 1.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   4 IILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISI-SWFPA-----FFVTGFLGGLTTFS 77
Cdd:PRK14203   8 LIWVALGSVLGGPARFFLSGLVARRIGETFPWGTLTVNVSGAFAIGIFGALAASGhGLFALpapwlFAVTGFLGCYTTVS 87


                 ...
gi 446546139  78 TLA 80
Cdd:PRK14203  88 SFS 90
PRK14204 PRK14204
fluoride efflux transporter CrcB;
9-117 2.67e-04

fluoride efflux transporter CrcB;


Pssm-ID: 172692  Cd Length: 127  Bit Score: 37.98  E-value: 2.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   9 IGGGLGAIARSAVTDYFNHKFT--SKLPIATLIVNLVGSFLIGLTIGLSISISW---FPAFFVTGFLGGLTTFSTLAKEl 83
Cdd:PRK14204  10 LGGAIGSSLRYFVGKMMPSKFLmfESFPLGTFSVNIIGCFVIGFMGHLAAKKVFgddFGIFFVTGVLGGFTTFSSYGLD- 88

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446546139  84 TLMMMPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14204  89 TLKLLQKSQYIEAISYVLGTNLLGLIGVAIGWFL 122
PRK14219 PRK14219
fluoride efflux transporter CrcB;
5-115 1.37e-03

fluoride efflux transporter CrcB;


Pssm-ID: 172707  Cd Length: 132  Bit Score: 35.98  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139   5 ILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPAFFV----TGFLGGLTTFSTLA 80
Cdd:PRK14219   4 IIVGIAGILGALSRYYLGLTIHEFWHHTFPLATLLINLAGCFLLAWLTTYIAKLNILPSDVItgigTGFIGSFTTFSTFS 83

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 446546139  81 KElTLMMMPKFNINLFLNYSLLQFIIGFIACYIGY 115
Cdd:PRK14219  84 VE-TIQLINHSEWSIAFLYVSCSILGGLIMSGLGY 117
ccrB PRK01636
fluoride efflux transporter CrcB;
34-114 4.28e-03

fluoride efflux transporter CrcB;


Pssm-ID: 179312  Cd Length: 118  Bit Score: 34.35  E-value: 4.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546139  34 PIATLIVNLVGSFLIGLTIGL--SISISWFPAFFV-TGFLGGLTTFSTLAKELTLMMMPKFNINLFLNYSLLQFIIGFIA 110
Cdd:PRK01636  18 PLDIFVANVVAAFLLGLTTSLhkRDKISQYVHLMIgTGIMGGLSTFSSFVYGAVEMAKSPGEVLVSICYLVASLIVGYIA 97


                 ....
gi 446546139 111 CYIG 114
Cdd:PRK01636  98 VELG 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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