|
Name |
Accession |
Description |
Interval |
E-value |
| murF |
PRK10773 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed |
1-452 |
0e+00 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed
Pssm-ID: 182718 [Multi-domain] Cd Length: 453 Bit Score: 888.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 1 MISVTLSKIADVLGAEHRGADLTLDTVITDTRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSRPLDIDLPQVIV 80
Cdd:PRK10773 1 MISVTLSQLADILNGELQGADITIDAVTTDTRKVTPGCLFVALKGERFDAHDFADDAKAAGAGALLVSRPLDIDLPQLVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 81 KDTRQAFGQLAAWVRMQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNFNNDIGVPITLLRLNHDYDYAVIELG 160
Cdd:PRK10773 81 KDTRLAFGQLAAWVRQQVPARVVALTGSSGKTSVKEMTAAILRQCGNTLYTAGNLNNDIGVPLTLLRLTPEHDYAVIELG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 161 ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRQVWRFS 240
Cdd:PRK10773 161 ANHQGEIAYTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADSNDWLNWQSVIGSKTVWRFS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 241 PNAANS-DFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVPGRLFP 319
Cdd:PRK10773 241 PNAANSvDFTATNIHVTSHGTEFTLHTPTGSVDVLLPLPGRHNIANALAAAALAMSVGATLDAVKAGLANLKAVPGRLFP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 320 IQLSENQLVLDDAYNANVGSMTAAVQVLSEMPGYRVLVVGDMAELGAESEACHIQVGEAAKAAGIDRVLSTGKLSQAISH 399
Cdd:PRK10773 321 IQLAEGQLLLDDSYNANVGSMTAAAQVLAEMPGYRVMVVGDMAELGAESEACHRQVGEAAKAAGIDKVLSVGKLSHAISE 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 446549293 400 ASGVGEHFADKAALIARLHALLQEQPMMTILVKGSRSAAMEDVVHALQEKGSC 452
Cdd:PRK10773 401 ASGVGEHFADKTALIARLKALLAEHQVITILVKGSRSAAMEEVVRALQENGTC 453
|
|
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
2-451 |
0e+00 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 571.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 2 ISVTLSKIADVLGAEHRGA-DLTLDTVITDTRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSRPLDIDLPQVIV 80
Cdd:COG0770 1 ILLTLAEIAEATGGRLIGDpDLVVTGVSTDSRKIKPGDLFVALKGERFDGHDFVAQALAKGAAAALVSRPLPADLPLIVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 81 KDTRQAFGQLAAWVRMQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNFNNDIGVPITLLRLNHDYDYAVIELG 160
Cdd:COG0770 81 DDTLKALQQLAAAHRARFNIPVIAITGSNGKTTTKEMLAAVLSTKGKVLATPGNFNNEIGVPLTLLRLPEDHEFAVLEMG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 161 ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRqVWRFS 240
Cdd:COG0770 161 MNHPGEIAYLARIARPDIAVITNIGPAHLEGFGSLEGIARAKGEIFEGLPPGGVAVLNADDPLLAALAERAKAR-VLTFG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 241 PNaANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVPGRLFPI 320
Cdd:COG0770 240 LS-EDADVRAEDIELDEDGTRFTLHTPGGELEVTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKGRLEVI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 321 QLSENQLVLDDAYNANVGSMTAAVQVLSEMP--GYRVLVVGDMAELGAESEACHIQVGEAAKAAGIDRVLSTGKLSQAIS 398
Cdd:COG0770 319 EGAGGVTLIDDSYNANPDSMKAALDVLAQLPggGRRIAVLGDMLELGEESEELHREVGELAAELGIDRLFTVGELARAIA 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 446549293 399 HASGV--GEHFADKAALIARLHALLQEQpmMTILVKGSRSAAMEDVVHALQEKGS 451
Cdd:COG0770 399 EAAGGerAEHFEDKEELLAALKALLRPG--DVVLVKGSRGMGLERVVEALKEGAA 451
|
|
| murF |
TIGR01143 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the ... |
29-446 |
1.06e-160 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273468 [Multi-domain] Cd Length: 417 Bit Score: 460.19 E-value: 1.06e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 29 TDTRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSRPLDID--LPQVIVKDTRQAFGQLAAWVRMQVPARVVALT 106
Cdd:TIGR01143 1 TDSRAIKPGDLFIALKGERFDGHDFVEQALAAGAVAVVVDREVGPDngLPQILVDDTLEALQALARAKRAKFSGKVIGIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 107 GSSGKTSVKEMTAAILSQCGNTLYTAGNFNNDIGVPITLLRLNHDYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAA 186
Cdd:TIGR01143 81 GSSGKTTTKEMLAAILSHKYKVFATPGNFNNEIGLPLTLLRAPGDHDYAVLEMGASHPGEIAYLAEIAKPDIAVITNIGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 187 AHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRQVWRFSPNaaNSDFTAANIHVTSHG-TEFTLQ 265
Cdd:TIGR01143 161 AHLEGFGSLEGIAEAKGEILQGLKENGIAVINADDPAFADLAKRLPNRNILSFGFE--GGDFVAKDISYSALGsTSFTLV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 266 TPMGSIDVLLPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVPGRLFpIQLSENQLVLDDAYNANVGSMTAAVQ 345
Cdd:TIGR01143 239 APGGEFEVSLPLLGRHNVMNALAAAALALELGIPLEEIAEGLAELKLVKGRFE-VQTKNGLTLIDDTYNANPDSMRAALD 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 346 VLSEMPGYRVLVVGDMAELGAESEACHIQVGEAAKAAGIDRVLSTGKLSQAISHASGV-GEHFADKAALIARLHALLQEQ 424
Cdd:TIGR01143 318 ALARFPGKKILVLGDMAELGEYSEELHAEVGRYANSLGIDLVFLVGEEAAVIYDSFGKqGKHFADKDELLAFLKTLVRKG 397
|
410 420
....*....|....*....|..
gi 446549293 425 PmmTILVKGSRSAAMEDVVHAL 446
Cdd:TIGR01143 398 D--VVLVKGSRSVKLEKVVEAL 417
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
27-447 |
1.46e-131 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 402.93 E-value: 1.46e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 27 VITDTRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSRPL-DIDLPQVIVKDTRQAFGQLAAWVRMQVPARVVAL 105
Cdd:PRK11929 529 VSTDSRSVGRGELFVALRGENFDGHDYLPQAFAAGACAAVVERQVaDVDLPQIVVDDTRAALGRLATAWRARFSLPVVAI 608
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 106 TGSSGKTSVKEMTAAILSQ---CGNTLYTAGNFNNDIGVPITLLRLNHDYDYAVIELGANHQGEIAWTVSLTRPEAALVN 182
Cdd:PRK11929 609 TGSNGKTTTKEMIAAILAAwqgEDRVLATEGNFNNEIGVPLTLLRLRAQHRAAVFELGMNHPGEIAYLAAIAAPTVALVT 688
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 183 NLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRQVWRF----SPNAANSDFTAANIHVTSH 258
Cdd:PRK11929 689 NAQREHQEFMHSVEAVARAKGEIIAALPEDGVAVVNGDDPYTAIWAKLAGARRVLRFglqpGADVYAEKIAKDISVGEAG 768
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 259 GTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVPGRLFPIQLSENQLVLDDAYNANVG 338
Cdd:PRK11929 769 GTRCQVVTPAGSAEVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQPVAGRMQRRRLSCGTRIIDDTYNANPD 848
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 339 SMTAAVQVLSEMP-GYRVLVVGDMAELGAESEACHIQVGEAAKAAGIDRVLSTGKLSQAISHASGVG--EHFADKAALIA 415
Cdd:PRK11929 849 SMRAAIDVLAELPnGPRALVLGDMLELGDNGPAMHREVGKYARQLGIDALITLGEAARDAAAAFGAGarGVCASVDEIIA 928
|
410 420 430
....*....|....*....|....*....|..
gi 446549293 416 RLHALLQEQPmmTILVKGSRSAAMEDVVHALQ 447
Cdd:PRK11929 929 ALRGALPEGD--SVLIKGSRFMRLERVVDALS 958
|
|
| PRK14093 |
PRK14093 |
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; ... |
5-449 |
2.53e-68 |
|
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional
Pssm-ID: 184501 [Multi-domain] Cd Length: 479 Bit Score: 225.42 E-value: 2.53e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 5 TLSKIADVLGAEHRGADLTLDTVIT-DTRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSRP----LDIDLPQVI 79
Cdd:PRK14093 8 TSDAMAEAMGATRSGALPRDVTGISiDSRTLAPGDAYFAIKGDVHDGHAFVAAALKAGAALAVVERAqrdkFAADAPLLV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 80 VKDTRQAFGQLAAWVRMQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNFNNDIGVPITLLRLNHDYDYAVIEL 159
Cdd:PRK14093 88 VDDVLAALRDLGRAARARLEAKVIAVTGSVGKTSTKEALRGVLGAQGETHASVASFNNHWGVPLSLARCPADARFAVFEI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 160 GANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRQVWRF 239
Cdd:PRK14093 168 GMNHAGEIEPLVKMVRPHVAIITTVEPVHLEFFSGIEAIADAKAEIFTGLEPGGAAVLNRDNPQFDRLAASARAAGIARI 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 240 SPNAANSDFTAANIHVTSHGTEFTLQTPMGSIDVL--LPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVPGRL 317
Cdd:PRK14093 248 VSFGADEKADARLLDVALHADCSAVHADILGHDVTykLGMPGRHIAMNSLAVLAAAELAGADLALAALALSQVQPAAGRG 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 318 FPIQLSENQ---LVLDDAYNANVGSMTAAVQVLSEMP----GYRVLVVGDMAELGAESEACHIQVGEAAKAAGIDRVLST 390
Cdd:PRK14093 328 VRHTLEVGGgeaTLIDESYNANPASMAAALGVLGRAPvgpqGRRIAVLGDMLELGPRGPELHRGLAEAIRANAIDLVFCC 407
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446549293 391 GKLSQAISHA--SGV-GEHFADKAALIARLHALLQEQPmmTILVKGSRSAAMEDVVHALQEK 449
Cdd:PRK14093 408 GPLMRNLWDAlsSGKrGGYAEDAAALESQVVAAIRAGD--VIMVKGSLGSRMKTIVTALEKR 467
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
27-358 |
2.82e-48 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 171.42 E-value: 2.82e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 27 VITDTRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSRPLDI---DLPQVIVKDTRQAFGQLAAWV--RMQVPAR 101
Cdd:COG0769 2 ITYDSRKVKPGDLFVALPGARVDGHDFIAQAIARGAVAVVTEAPGALlaaGVPVIVVPDPRAALALLAAAFygHPSQKLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 102 VVALTGSSGKTSVKEMTAAILSQCGntlYTAGNF---NNDIGV-----------PITLLRL-----NHDYDYAVIE---- 158
Cdd:COG0769 82 LIGVTGTNGKTTTTYLLAQILRALG---KKTGLIgtvGNGIGGelipsslttpeALDLQRLlaemvDAGVTHVVMEvssh 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 159 -LganHQGEIA--------WTvSLTRPeaalvnnlaaaHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQS 229
Cdd:COG0769 159 aL---DQGRVDgvrfdvavFT-NLTRD-----------HLDYHGTMEAYFAAKARLFDQLGPGGAAVINADDPYGRRLAA 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 230 IIGDRqVWRFSPNaANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATLTAVKAGLAA 309
Cdd:COG0769 224 AAPAR-VITYGLK-ADADLRATDIELSADGTRFTLVTPGGEVEVRLPLIGRFNVYNALAAIAAALALGIDLEEILAALEK 301
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 446549293 310 LKAVPGRLFPIQLSENQLVLDDaYNANVGSMTAAVQVLSEMPGYRVLVV 358
Cdd:COG0769 302 LKGVPGRMERVDGGQGPTVIVD-YAHTPDALENVLEALRPHTKGRLIVV 349
|
|
| PRK11930 |
PRK11930 |
putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine ... |
2-449 |
3.99e-45 |
|
putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional
Pssm-ID: 237026 [Multi-domain] Cd Length: 822 Bit Score: 167.83 E-value: 3.99e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 2 ISVTLSKIADVLGAEHRG-ADLTLDTVITDTRKVT--PGCLFVALKGERFDAHDFADKAKANGAGALLVSRPLDID--LP 76
Cdd:PRK11930 1 MSYTLESISGILGAEGLGdKDAIIDQILTDSRSLSfpENTLFFALKGERNDGHRYIQELYEKGVRNFVVSEEKHPEesYP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 77 QV---IVKDTRQAFGQLAAWVRMQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNFNNDIGVPITLLRLNHDYD 153
Cdd:PRK11930 81 DAnflKVKDPLKALQELAAYHRSQFDIPVIGITGSNGKTIVKEWLYQLLSPDYNIVRSPRSYNSQIGVPLSVWQLNEEHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 154 YAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGS--------LAGVAKAKGEIYTGLPEngiAIMNADNNDWL 225
Cdd:PRK11930 161 LGIFEAGISQPGEMEALQKIIKPTIGILTNIGGAHQENFRSikqkimekLKLFKDCDVIIYNGDNE---LISSCITKSNL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 226 NWQSIIGDR---QVWRFSPNAANSDFtAANIHVTSHGTEFTLQTP---MGSIDVLLplpgrhNIanalaaAALSMAVGAT 299
Cdd:PRK11930 238 TLKLISWSRkdpEAPLYIPFVEKKED-HTVISYTYKGEDFHFEIPfidDASIENLI------HC------IAVLLYLGYS 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 300 LTAVKAGLAALKAVPGRLFPIQLSENQLVLDDAYNANVGSMTAAVQVLS--EMPGYRVLVVGDMAELGAESEACHIQVGE 377
Cdd:PRK11930 305 ADQIQERMARLEPVAMRLEVKEGINNCTLINDSYNSDLQSLDIALDFLNrrSQSKKKTLILSDILQSGQSPEELYRKVAQ 384
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446549293 378 AAKAAGIDRVLSTGK--LSQAISHASGVGEHFADKAALIARLHALLQEQPmmTILVKGSRSAAMEDVVHALQEK 449
Cdd:PRK11930 385 LISKRGIDRLIGIGEeiSSEASKFEGTEKEFFKTTEAFLKSFAFLKFRNE--LILVKGARKFEFEQITELLEQK 456
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
106-283 |
1.16e-42 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 149.38 E-value: 1.16e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 106 TGSSGKTSVKEMTAAILSQCGNTLYTAG--------NFNNDIGVPITLLRL-NHDYDYAVIELGANHQGEiAWTVSLTRP 176
Cdd:pfam08245 2 TGTNGKTTTTELIAAILSLAGGVIGTIGtyigksgnTTNNAIGLPLTLAEMvEAGAEYAVLEVSSHGLGE-GRLSGLLKP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 177 EAALVNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDR--QVWRFSPNaANSDFTAANIH 254
Cdd:pfam08245 81 DIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIAKLKKAgvRVITYGIE-GEADLRAANIE 159
|
170 180 190
....*....|....*....|....*....|
gi 446549293 255 VTSHGTEFTL-QTPMGSIDVLLPLPGRHNI 283
Cdd:pfam08245 160 LSSDGTSFDLfTVPGGELEIEIPLLGRHNV 189
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
20-317 |
3.72e-32 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 127.56 E-value: 3.72e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 20 ADLTLDTVITDTRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSRPLDI--DLPQVIVKDTRQAFGQLAAWV--R 95
Cdd:PRK00139 11 APVEITGLTYDSRKVKPGDLFVALPGHKVDGRDFIAQAIANGAAAVVAEADGEAgtGVPVIIVPDLRKALALLAAAFygH 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 96 MQVPARVVALTGSSGKTSVKEMTAAILSQCGNT---LYTAGNFNNDIGVP--------ITLLRLNHDY-----DYAVIE- 158
Cdd:PRK00139 91 PSDKLKLIGVTGTNGKTTTAYLLAQILRLLGEKtalIGTLGNGIGGELIPsglttpdaLDLQRLLAELvdagvTYAAMEv 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 159 ----LganHQGEIAWTV-------SLTRpeaalvnnlaaAHLEGFGSLAGVAKAKGEIYTGLpeNGIAIMNADNNdwlNW 227
Cdd:PRK00139 171 sshaL---DQGRVDGLKfdvavftNLSR-----------DHLDYHGTMEDYLAAKARLFSEL--GLAAVINADDE---VG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 228 QSIIGDRQVWRFSPNAAnsDFTAANIHVTSHGTEFTLQTpmgsiDVLLPLPGRHNIANALAAAALSMAVGATLTAVKAGL 307
Cdd:PRK00139 232 RRLLALPDAYAVSMAGA--DLRATDVEYTDSGQTFTLVT-----EVESPLIGRFNVSNLLAALAALLALGVPLEDALAAL 304
|
330
....*....|
gi 446549293 308 AALKAVPGRL 317
Cdd:PRK00139 305 AKLQGVPGRM 314
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
21-358 |
2.58e-31 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 125.12 E-value: 2.58e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 21 DLTLDTVITDTRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSRPLDIDL---PQVIVKDTRQAFGQLAAWVrMQ 97
Cdd:TIGR01085 1 DLEVTGLTLDSREVKPGDLFVAIKGTHVDGHDFIHDAIANGAVAVVVERDVDFYVapvPVIIVPDLRHALSSLAAAF-YG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 98 VPAR---VVALTGSSGKTSVKEMTAAILSQCG------NTLYTAGNFNNDIGVP--------ITLLRLNHDY-----DYA 155
Cdd:TIGR01085 80 HPSKklkVIGVTGTNGKTTTTSLIAQLLRLLGkktgliGTIGYRLGGNDLIKNPaalttpeaLTLQSTLAEMveagaQYA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 156 VIELgANH---QGEIA--------WTvSLTRpeaalvnnlaaAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNAD---N 221
Cdd:TIGR01085 160 VMEV-SSHalaQGRVRgvrfdaavFT-NLSR-----------DHLDFHGTMENYFAAKASLFTELGLKRFAVINLDdeyG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 222 NDWLN------WQSIIGDRQVWRfspnaaNSDFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIanalAAAALSMA 295
Cdd:TIGR01085 227 AQFVKrlpkdiTVSAITQPADGR------AQDIKITDSGYSFEGQQFTFETPAGEGHLHTPLIGRFNV----YNLLAALA 296
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446549293 296 VGATLTAVK-----AGLAALKAVPGRLFPIQLSENQLVLDDaYNANVGSMTAAVQVLSEMPGYRVLVV 358
Cdd:TIGR01085 297 TLLHLGGIDledivAALEKFRGVPGRMELVDGGQKFLVIVD-YAHTPDALEKALRTLRKHKDGRLIVV 363
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
9-331 |
4.06e-27 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 114.80 E-value: 4.06e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 9 IADVLGAEHRGADLTLDTvitdtRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSR-PLDIDLP----QVIVKDT 83
Cdd:PRK11929 19 LAWLRGCVAATADLRLDS-----REVQPGDLFVACRGAASDGRAFIDQALARGAAAVLVEAeGEDQVAAadalVLPVADL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 84 RQAFGQLAA--WVRMQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNFNNDIGV-----------PITLLRLNH 150
Cdd:PRK11929 94 RKALGELAArwYGRPSEQLSLVAVTGTNGKTSCAQLLAQLLTRLGKPCGSIGTLGARLDGrlipgslttpdAIILHRILA 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 151 DY-----DYAVIElgANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWL 225
Cdd:PRK11929 174 RMraagaDAVAME--ASSHGLEQGRLDGLRIAVAGFTNLTRDHLDYHGTMQDYEEAKAALFSKLPGLGAAVINADDPAAA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 226 NWQSII--GDRQVWrfSPNAANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATLTAV 303
Cdd:PRK11929 252 RLLAALprGLKVGY--SPQNAGADVQARDLRATAHGQVFTLATPDGSYQLVTRLLGRFNVSNLLLVAAALKKLGLPLAQI 329
|
330 340 350
....*....|....*....|....*....|.
gi 446549293 304 KAGLAALKAVPGRL---FPIQLSENQLVLDD 331
Cdd:PRK11929 330 ARALAAVSPVPGRMervGPTAGAQGPLVVVD 360
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
90-317 |
1.69e-14 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 75.12 E-value: 1.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 90 LAAWVrmqVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNfnndIGVP-ITLLRLNHDYDYAVIELGAnHQgeIA 168
Cdd:COG0771 98 LAYRL---SPAPIIAITGTNGKTTTTTLIGHILKAAGLRVAVGGN----IGTPlLDLLLEPEPPDVYVLELSS-FQ--LE 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 169 WTVSLT---------RPEaalvnnlaaaHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRQVWrF 239
Cdd:COG0771 168 TTPSLRpdvavilniTPD----------HLDRHGSMEAYAAAKARIFANQTPDDYAVLNADDPLTRALAEEAKARVVP-F 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 240 SPN-AANSDFTAAN--IHVTSHGTEftlqtpmgSIDV-LLPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVPG 315
Cdd:COG0771 237 SLKePLEGGAGLEDgkLVDRASGEE--------LLPVdDLRLPGRHNLENALAALAAARALGVPPEAIREALRSFKGLPH 308
|
..
gi 446549293 316 RL 317
Cdd:COG0771 309 RL 310
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
89-359 |
1.90e-14 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 75.07 E-value: 1.90e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 89 QLAAWVrmqVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNfnndIGVPITLLRLNHDYDYAVIELgANHQgeIA 168
Cdd:TIGR01087 94 ELFLRL---VPLPVVAITGTNGKTTTTSLLYHLLKAAGLKAFLGGN----IGTPALEVLDQEGAELYVLEL-SSFQ--LE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 169 WTVSLtRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRQVWRFSPNAANSDF 248
Cdd:TIGR01087 164 TTESL-RPEIALILNISEDHLDWHGSFEDYVAAKLKIFARQTEGDVAVLNADDPRFARLAQKSKAQVIWFSVEKDAERGL 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 249 TAANIHVTSHGTeftlqtpmgsiDVLLPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVPGRLFPIQLSENQLV 328
Cdd:TIGR01087 243 CIRDGGLYLKPN-----------DLEGSLLGLHNAENILAAIALAKSLGLNLEAILEALRSFKGLPHRLEYVGQKNGVHF 311
|
250 260 270
....*....|....*....|....*....|.
gi 446549293 329 LDDAYNANVGsmtAAVQVLSEMPGYRVLVVG 359
Cdd:TIGR01087 312 YNDSKATNVH---ATLAALSAFDNPVILIVG 339
|
|
| PRK14022 |
PRK14022 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase; |
21-134 |
1.81e-12 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase;
Pssm-ID: 237588 [Multi-domain] Cd Length: 481 Bit Score: 68.91 E-value: 1.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 21 DLTLDTVITDTRKVTPGCLFVAlKGERFdAHDFADKAKANGAGALLVSRPLDIDLPQVIVKDTRQAFgQLAAWVRMQVPA 100
Cdd:PRK14022 31 GVQFDDISYDSRTADEGTLFFA-KGAYF-KHKFLQNAITQGLKLYVSEKDYEVGIPQVIVPDIKKAM-SLIAMEFYDNPQ 107
|
90 100 110
....*....|....*....|....*....|....*...
gi 446549293 101 ---RVVALTGSSGKTSVKEMTAAILSQCG-NTLYTAGN 134
Cdd:PRK14022 108 hklKLLAFTGTKGKTTAAYFAYHILKQLHkPAMLSTMN 145
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
313-392 |
7.25e-12 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 61.21 E-value: 7.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 313 VPGRLFPIQLSENQLVLDDaYNANVGSMTAAVQVLSEM-PGYRVLVVGDMAELGAEseaCHIQVGEAAKAAGiDRVLSTG 391
Cdd:pfam02875 1 VPGRLEVVGENNGVLVIDD-YAHNPDAMEAALRALRNLfPGRLILVFGGMGDRDAE---FHALLGRLAAALA-DVVILTG 75
|
.
gi 446549293 392 K 392
Cdd:pfam02875 76 D 76
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
29-92 |
7.98e-11 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 58.01 E-value: 7.98e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446549293 29 TDTRKVTPGCLFVALKGERFDAHDFADKAKANGAGALLVSRPLD-----------IDLPQVIVKDTRQAFGQLAA 92
Cdd:pfam01225 7 IDGRGMSPGALFLALKGYRVDGSDFIESLIALGAAAVVGHDAANnispdnpeleaAKVPGIPVIDRREALAELAA 81
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
101-333 |
1.05e-07 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 53.85 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 101 RVVALTGSSGKTSVKEMTAAILSQCG-NTLYTAGNFNNDIGvpiTLLRLNHDyDYAVIELG------ANHQGEIAwTVSL 173
Cdd:TIGR01082 100 HSIAVAGTHGKTTTTAMIAVILKEAGlDPTVVVGGLVKEAG---TNARLGSG-EYLVAEADesdasfLHLQPNVA-IVTN 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 174 TRPEaalvnnlaaaHLEGFG-SLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGdRQVWRFSPNAANSDFTAAN 252
Cdd:TIGR01082 175 IEPD----------HLDTYGsSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELVPKAT-EQVITYGGSGEDADYRAEN 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 253 IHVTSHGTEFTLQTPM-GSIDVLLPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVpGRLFPIQLSENQLVLDD 331
Cdd:TIGR01082 244 IQQSGAEGKFSVRGKGkLYLEFTLNLPGRHNVLNALAAIAVALELGIDFEAILRALANFQGV-KRRFEILGEFGGVLLID 322
|
..
gi 446549293 332 AY 333
Cdd:TIGR01082 323 DY 324
|
|
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
188-331 |
1.99e-07 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 53.15 E-value: 1.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 188 HLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNdwlNWQSIIG--DRQVWRFSPNAaNSDFTAANIHVTSHGTEFTLQ 265
Cdd:COG0773 184 HLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDP---GLRELLPrcGRPVITYGFSE-DADYRAENIRIDGGGSTFDVL 259
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446549293 266 TPMGSI-DVLLPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVPGRLFPIQLSENQLVLDD 331
Cdd:COG0773 260 RRGEELgEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRRFELKGEVGGVTVIDD 326
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
99-317 |
1.43e-05 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 47.27 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 99 PARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNfnndIGVPI--TLLRLNHDyDYAVIELgANHQGEiawTVSLTRP 176
Cdd:PRK14106 107 KAPIVAITGTNGKTTTTTLLGEIFKNAGRKTLVAGN----IGYPLidAVEEYGED-DIIVAEV-SSFQLE---TIKEFKP 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 177 EAALVNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNdwlNWQSIIG--DRQVWRFSPNA--ANSDFTAAN 252
Cdd:PRK14106 178 KVGCILNITPDHLDRHKTMENYIKAKARIFENQRPSDYTVLNYDDP---RTRSLAKkaKARVIFFSRKSllEEGVFVKNG 254
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446549293 253 -IHVTSHGTEftlqTPMGSIDVLlPLPGRHNIANALAAAALSMAVGATLTAVKAGLAALKAVPGRL 317
Cdd:PRK14106 255 kIVISLGGKE----EEVIDIDEI-FIPGEHNLENALAATAAAYLLGISPDVIANTLKTFKGVEHRI 315
|
|
| LpxD |
COG1044 |
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [Cell wall/membrane/envelope ... |
3-93 |
1.69e-03 |
|
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [Cell wall/membrane/envelope biogenesis]; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase is part of the Pathway/BioSystem: Lipid A biosynthesis
Pssm-ID: 440666 [Multi-domain] Cd Length: 335 Bit Score: 40.39 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446549293 3 SVTLSKIADVLGAEHRGADltlDTVITDTRKV---TPGCL-FVAlkGERfdahdFADKAKANGAGALLVSRPLDIDLPQ- 77
Cdd:COG1044 1 SFTLAELAELLGGELVGDG---DLEITGVAPLeeaGPGDLsFLA--NPK-----YAKQLATTKASAVIVPPDFAAALPGl 70
|
90
....*....|....*...
gi 446549293 78 --VIVKDTRQAFGQLAAW 93
Cdd:COG1044 71 alIVVDNPYLAFAKLLQL 88
|
|
| |
