|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08638 |
PRK08638 |
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB; |
1-330 |
0e+00 |
|
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB;
Pssm-ID: 236317 [Multi-domain] Cd Length: 333 Bit Score: 528.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 1 MITKKLPLHIADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIAC 80
Cdd:PRK08638 2 HITYDLPVAIDDIIEAKQRLAGRIRKTPLPRSNYLSERCKGEIFLKLENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVAC 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 81 SAGNHAQGIALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAG 160
Cdd:PRK08638 82 SAGNHAQGVALSCALLGIDGKVVMPKGAPKSKVAATCGYGAEVVLHGDNFNDTIAKVEEIVEEEGRTFIPPYDDPKVIAG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 161 QGTIGLDILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVK 240
Cdd:PRK08638 162 QGTIGLEILEDLWDVDTVIVPIGGGGLIAGIAVALKSINPTIHIIGVQSENVHGMAASFYAGEITTHRTTGTLADGCDVS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 241 IPGDLTFEVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDPYIKGKKVVAVISGGNVDLQRIS 320
Cdd:PRK08638 242 RPGNLTYEIVRELVDDIVLVSEDEIRNAMKDLIQRNKVVTEGAGALATAALLSGKLDQYIQNKKVVAIISGGNVDLSRVS 321
|
330
....*....|
gi 446551549 321 SVCEQFFVAN 330
Cdd:PRK08638 322 QITGHVVAAD 331
|
|
| Thr-dehyd |
cd01562 |
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. ... |
10-315 |
5.90e-141 |
|
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.
Pssm-ID: 107205 [Multi-domain] Cd Length: 304 Bit Score: 400.71 E-value: 5.90e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 10 IADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGI 89
Cdd:cd01562 1 LEDILAAAARIKPVVRRTPLLTSPTLSELLGAEVYLKCENLQKTGSFKIRGAYNKLLSLSEEERAKGVVAASAGNHAQGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 90 ALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDIL 169
Cdd:cd01562 81 AYAAKLLGIPATIVMPETAPAAKVDATRAYGAEVVLYGEDFDEAEAKARELAEEEGLTFIHPFDDPDVIAGQGTIGLEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 170 DDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIPGDLTFEV 249
Cdd:cd01562 161 EQVPDLDAVFVPVGGGGLIAGIATAVKALSPNTKVIGVEPEGAPAMAQSLAAGKPVTLPEVDTIADGLAVKRPGELTFEI 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446551549 250 VNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDpyIKGKKVVAVISGGNVD 315
Cdd:cd01562 241 IRKLVDDVVTVSEDEIAAAMLLLFEREKLVAEPAGALALAALLSGKLD--LKGKKVVVVLSGGNID 304
|
|
| IlvA |
COG1171 |
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the ... |
4-329 |
7.80e-131 |
|
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440784 [Multi-domain] Cd Length: 327 Bit Score: 375.91 E-value: 7.80e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 4 KKLPLHIADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAG 83
Cdd:COG1171 2 TALMPTLADIEAAAARIAGVVRRTPLLRSPTLSERLGAEVYLKLENLQPTGSFKLRGAYNALASLSEEERARGVVAASAG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 84 NHAQGIALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGT 163
Cdd:COG1171 82 NHAQGVAYAARLLGIPATIVMPETAPAVKVAATRAYGAEVVLHGDTYDDAEAAAAELAEEEGATFVHPFDDPDVIAGQGT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 164 IGLDILDDMWDVDTVivpiggggiisgiAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIPG 243
Cdd:COG1171 162 IALEILEQLPDLDAVfvpvggggliagvAAALKALSPDIRVIGVEPEGAAAMYRSLAAGEPVTLPGVDTIADGLAVGRPG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 244 DLTFEVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDpyIKGKKVVAVISGGNVDLQRISSVC 323
Cdd:COG1171 242 ELTFEILRDLVDDIVTVSEDEIAAAMRLLLERTKIVVEPAGAAALAALLAGKER--LKGKRVVVVLSGGNIDPDRLAEIL 319
|
....*.
gi 446551549 324 EQFFVA 329
Cdd:COG1171 320 ERGLVG 325
|
|
| ilvA_1Cterm |
TIGR01127 |
threonine ammonia-lyase, medium form; A form of threonine dehydratase with two copies of the ... |
27-322 |
2.50e-110 |
|
threonine ammonia-lyase, medium form; A form of threonine dehydratase with two copies of the C-terminal domain pfam00585 is described by TIGR01124. This model describes a phylogenetically distinct form with a single copy of pfam00585. This form branches with the catabolic threonine dehydratase of E. coli; many members are designated as catabolic for this reason. However, the catabolic form lacks any pfam00585 domain. Many members of this model are found in species with other Ile biosynthetic enzymes. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130197 [Multi-domain] Cd Length: 380 Bit Score: 325.93 E-value: 2.50e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 27 TPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGIALSAHLLGIKSKIVMPI 106
Cdd:TIGR01127 1 TPLIYSTTLSDITGSEVYLKLENLQKTGSFKIRGALNKIANLSEDQRQRGVVAASAGNHAQGVAYAAKKFGIKAVIVMPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 107 SAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDILDDMWDVDTVIVPIGGGG 186
Cdd:TIGR01127 81 SAPPSKVKATKSYGAEVILHGDDYDEAYAFATSLAEEEGRVFVHPFDDEFVMAGQGTIGLEIMEDIPDVDTVIVPVGGGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 187 IISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIPGDLTFEVVNELVDDIVTVSEGELE 266
Cdd:TIGR01127 161 LISGVASAAKQINPNVKVIGVEAEGAPSMYESLREGKIKAVESVRTIADGIAVKKPGDLTFNIIKEYVDDVVTVDEEEIA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 446551549 267 VAMKDLLQRGKAVVEGAGALATAALLAGKVDPyiKGKKVVAVISGGNVDLQRISSV 322
Cdd:TIGR01127 241 NAIYLLLERHKILAEGAGAAGVAALLEQKVDV--KGKKIAVVLSGGNIDLNLLNKI 294
|
|
| PRK07334 |
PRK07334 |
threonine dehydratase; Provisional |
6-324 |
1.84e-95 |
|
threonine dehydratase; Provisional
Pssm-ID: 235994 [Multi-domain] Cd Length: 403 Bit Score: 288.72 E-value: 1.84e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 6 LPLHIADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNH 85
Cdd:PRK07334 3 LMVTLADIRAAAARLAGQVLRTPCVHSRTLSQITGAEVWLKFENLQFTASFKERGALNKLLLLTEEERARGVIAMSAGNH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 86 AQGIALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIG 165
Cdd:PRK07334 83 AQGVAYHAQRLGIPATIVMPRFTPTVKVERTRGFGAEVVLHGETLDEARAHARELAEEEGLTFVHPYDDPAVIAGQGTVA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 166 LDILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKAsYDKGTIVeHYEAPTIADGCAVKIPGDL 245
Cdd:PRK07334 163 LEMLEDAPDLDTLVVPIGGGGLISGMATAAKALKPDIEIIGVQTELYPSMYA-AIKGVAL-PCGGSTIAEGIAVKQPGQL 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446551549 246 TFEVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKvdPYIKGKKVVAVISGGNVDLQRISSVCE 324
Cdd:PRK07334 241 TLEIVRRLVDDILLVSEADIEQAVSLLLEIEKTVVEGAGAAGLAALLAYP--ERFRGRKVGLVLSGGNIDTRLLANVLL 317
|
|
| PRK07048 |
PRK07048 |
threo-3-hydroxy-L-aspartate ammonia-lyase; |
6-321 |
3.97e-88 |
|
threo-3-hydroxy-L-aspartate ammonia-lyase;
Pssm-ID: 235918 [Multi-domain] Cd Length: 321 Bit Score: 267.27 E-value: 3.97e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 6 LPLHIADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNH 85
Cdd:PRK07048 4 LLPTYDDVAAAAARLAGVAHRTPVLTSRTADARTGAQVFFKCENFQRMGAFKFRGAYNALSQFSPEQRRAGVVTFSSGNH 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 86 AQGIALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIG 165
Cdd:PRK07048 84 AQAIALSARLLGIPATIVMPQDAPAAKVAATRGYGGEVVTYDRYTEDREEIGRRLAEERGLTLIPPYDHPHVIAGQGTAA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 166 LDILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVeHYEAP-TIADGCAVKIPGD 244
Cdd:PRK07048 164 KELFEEVGPLDALFVCLGGGGLLSGCALAARALSPGCKVYGVEPEAGNDGQQSFRSGEIV-HIDTPrTIADGAQTQHLGN 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446551549 245 LTFEVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDpyIKGKKVVAVISGGNVDLQRISS 321
Cdd:PRK07048 243 YTFPIIRRLVDDIVTVSDAELVDAMRFFAERMKIVVEPTGCLGAAAALRGKVP--LKGKRVGVIISGGNVDLARFAA 317
|
|
| PRK09224 |
PRK09224 |
threonine ammonia-lyase IlvA; |
24-324 |
1.14e-87 |
|
threonine ammonia-lyase IlvA;
Pssm-ID: 236417 [Multi-domain] Cd Length: 504 Bit Score: 272.01 E-value: 1.14e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 24 ARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGIALSAHLLGIKSKIV 103
Cdd:PRK09224 18 AQETPLEKAPKLSARLGNQVLLKREDLQPVFSFKLRGAYNKMAQLTEEQLARGVITASAGNHAQGVALSAARLGIKAVIV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 104 MPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDILDDMWD-VDTVIVPI 182
Cdd:PRK09224 98 MPVTTPDIKVDAVRAFGGEVVLHGDSFDEAYAHAIELAEEEGLTFIHPFDDPDVIAGQGTIAMEILQQHPHpLDAVFVPV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 183 GGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIPGDLTFEVVNELVDDIVTVSE 262
Cdd:PRK09224 178 GGGGLIAGVAAYIKQLRPEIKVIGVEPEDSACLKAALEAGERVDLPQVGLFADGVAVKRIGEETFRLCQEYVDDVITVDT 257
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446551549 263 GELEVAMKDLLQRGKAVVEgagalataallagkvdP-----------Y-----IKGKKVVAVISGGNVDLQRISSVCE 324
Cdd:PRK09224 258 DEICAAIKDVFEDTRSIAE----------------PagalalaglkkYvaqhgIEGETLVAILSGANMNFDRLRYVAE 319
|
|
| ilvA_2Cterm |
TIGR01124 |
threonine ammonia-lyase, biosynthetic, long form; This model describes a form of threonine ... |
24-325 |
2.79e-85 |
|
threonine ammonia-lyase, biosynthetic, long form; This model describes a form of threonine ammonia-lyase, a pyridoxal-phosphate dependent enzyme, with two copies of the threonine dehydratase C-terminal domain (pfam00585). Members with known function participate in isoleucine biosynthesis and are inhibited by isoleucine. Alternate name: threonine deaminase, threonine dehydratase. Forms scoring between the trusted and noise cutoff tend to branch with this subgroup of threonine ammonia-lyase phylogenetically but have only a single copy of the C-terminal domain. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130194 [Multi-domain] Cd Length: 499 Bit Score: 265.83 E-value: 2.79e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 24 ARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGIALSAHLLGIKSKIV 103
Cdd:TIGR01124 15 AQETPLQKAAKLSERLGNRILIKREDLQPVFSFKLRGAYNKMAQLSPEQKARGVIAASAGNHAQGVAFSAARLGLKALIV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 104 MPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDIL-DDMWDVDTVIVPI 182
Cdd:TIGR01124 95 MPETTPDIKVDAVRGFGGEVVLHGANFDDAKAKAIELSQEKGLTFIHPFDDPLVIAGQGTLALEILrQVANPLDAVFVPV 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 183 GGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIPGDLTFEVVNELVDDIVTVSE 262
Cdd:TIGR01124 175 GGGGLAAGVAALIKQLMPEIKVIGVEPTDSDCMKQALDAGEPVDLDQVGLFADGVAVKRVGDETFRLCQQYLDDIVTVDT 254
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446551549 263 GELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDPYIKGKKVVAVISGGNVDLQRISSVCEQ 325
Cdd:TIGR01124 255 DEVCAAIKDLFEDTRAVAEPAGALALAGLKKYVALHGIRGQTLVAILSGANMNFHRLRYVSER 317
|
|
| PRK06815 |
PRK06815 |
threonine/serine dehydratase; |
13-323 |
2.30e-84 |
|
threonine/serine dehydratase;
Pssm-ID: 180709 [Multi-domain] Cd Length: 317 Bit Score: 257.31 E-value: 2.30e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 13 IKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGIALS 92
Cdd:PRK06815 7 ILEAHQRLRPQVRVTPLEHSPLLSQHTGCEVYLKCEHLQHTGSFKFRGASNKLRLLNEAQRQQGVITASSGNHGQGVALA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 93 AHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDILDDM 172
Cdd:PRK06815 87 AKLAGIPVTVYAPEQASAIKLDAIRALGAEVRLYGGDALNAELAARRAAEQQGKVYISPYNDPQVIAGQGTIGMELVEQQ 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 173 WDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKI-PGDLTFEVVN 251
Cdd:PRK06815 167 PDLDAVFVAVGGGGLISGIATYLKTLSPKTEIIGCWPANSPSLYTSLEAGEIVEVAEQPTLSDGTAGGVePGAITFPLCQ 246
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446551549 252 ELVDDIVTVSEGELEVAMKDLLQRGKAVVEgaGALATAALLAGKVDPYIKGKKVVAVISGGNVDLQRISSVC 323
Cdd:PRK06815 247 QLIDQKVLVSEEEIKEAMRLIAETDRWLIE--GAAGVALAAALKLAPRYQGKKVAVVLCGKNIVLEKYLEAV 316
|
|
| PRK08639 |
PRK08639 |
threonine dehydratase; Validated |
3-324 |
2.58e-83 |
|
threonine dehydratase; Validated
Pssm-ID: 236318 [Multi-domain] Cd Length: 420 Bit Score: 258.20 E-value: 2.58e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 3 TKKLPLHIADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSA 82
Cdd:PRK08639 2 TVKMTVSAKDIDKAAKRLKDVVPETPLQRNDYLSEKYGANVYLKREDLQPVRSYKLRGAYNAISQLSDEELAAGVVCASA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 83 GNHAQGIALSAHLLGIKSKIVMPISAPLAKVEATRGYGS---EVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMA 159
Cdd:PRK08639 82 GNHAQGVAYACRHLGIPGVIFMPVTTPQQKIDQVRFFGGefvEIVLVGDTFDDSAAAAQEYAEETGATFIPPFDDPDVIA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 160 GQGTIGLDILDDM---WDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADG 236
Cdd:PRK08639 162 GQGTVAVEILEQLekeGSPDYVFVPVGGGGLISGVTTYLKERSPKTKIIGVEPAGAASMKAALEAGKPVTLEKIDKFVDG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 237 CAVKIPGDLTFEVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDpyIKGKKVVAVISGGNVDL 316
Cdd:PRK08639 242 AAVARVGDLTFEILKDVVDDVVLVPEGAVCTTILELYNKEGIVAEPAGALSIAALELYKDE--IKGKTVVCVISGGNNDI 319
|
....*...
gi 446551549 317 QRISSVCE 324
Cdd:PRK08639 320 ERMPEIKE 327
|
|
| PLN02970 |
PLN02970 |
serine racemase |
1-319 |
1.44e-78 |
|
serine racemase
Pssm-ID: 215524 [Multi-domain] Cd Length: 328 Bit Score: 243.05 E-value: 1.44e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 1 MITKKLPLHIADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIAC 80
Cdd:PLN02970 2 AASEKYAADLSSIREARKRIAPFIHRTPVLTSSSLDALAGRSLFFKCECFQKGGAFKFRGACNAIFSLSDDQAEKGVVTH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 81 SAGNHAQGIALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAG 160
Cdd:PLN02970 82 SSGNHAAALALAAKLRGIPAYIVVPKNAPACKVDAVIRYGGIITWCEPTVESREAVAARVQQETGAVLIHPYNDGRVISG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 161 QGTIGLDILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVK 240
Cdd:PLN02970 162 QGTIALEFLEQVPELDVIIVPISGGGLISGIALAAKAIKPSIKIIAAEPKGADDAAQSKAAGEIITLPVTNTIADGLRAS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 241 IpGDLTFEVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGAL--ATAALLAGKVDPYIKG-KKVVAVISGGNVDLQ 317
Cdd:PLN02970 242 L-GDLTWPVVRDLVDDVITVDDKEIIEAMKLCYERLKVVVEPSGAIglAAALSDSFRSNPAWKGcKNVGIVLSGGNVDLG 320
|
..
gi 446551549 318 RI 319
Cdd:PLN02970 321 VL 322
|
|
| eutB |
PRK07476 |
threonine dehydratase; Provisional |
10-316 |
1.35e-75 |
|
threonine dehydratase; Provisional
Pssm-ID: 236025 [Multi-domain] Cd Length: 322 Bit Score: 235.25 E-value: 1.35e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 10 IADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGI 89
Cdd:PRK07476 3 LADIYRARRRIAGRVRRTPLVASASLSARAGVPVWLKLETLQPTGSFKLRGATNALLSLSAQERARGVVTASTGNHGRAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 90 ALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDIL 169
Cdd:PRK07476 83 AYAARALGIRATICMSRLVPANKVDAIRALGAEVRIVGRSQDDAQAEVERLVREEGLTMVPPFDDPRIIAGQGTIGLEIL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 170 DDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIAD--GCAVKIPGDLTF 247
Cdd:PRK07476 163 EALPDVATVLVPLSGGGLASGVAAAVKAIRPAIRVIGVSMERGAAMHASLAAGRPVQVEEVPTLADslGGGIGLDNRYTF 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446551549 248 EVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDPyiKGKKVVAVISGGNVDL 316
Cdd:PRK07476 243 AMCRALLDDVVLLDEAEIAAGIRHAYREERLVVEGAGAVGIAALLAGKIAA--RDGPIVVVVSGANIDM 309
|
|
| PRK12483 |
PRK12483 |
threonine dehydratase; Reviewed |
24-325 |
2.56e-75 |
|
threonine dehydratase; Reviewed
Pssm-ID: 237111 [Multi-domain] Cd Length: 521 Bit Score: 240.47 E-value: 2.56e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 24 ARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGIALSAHLLGIKSKIV 103
Cdd:PRK12483 35 ARETPLQRAPNLSARLGNQVLLKREDLQPVFSFKIRGAYNKMARLPAEQLARGVITASAGNHAQGVALAAARLGVKAVIV 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 104 MPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDIL-DDMWDVDTVIVPI 182
Cdd:PRK12483 115 MPRTTPQLKVDGVRAHGGEVVLHGESFPDALAHALKLAEEEGLTFVPPFDDPDVIAGQGTVAMEILrQHPGPLDAIFVPV 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 183 GGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIPGDLTFEVVNELVDDIVTVSE 262
Cdd:PRK12483 195 GGGGLIAGIAAYVKYVRPEIKVIGVEPDDSNCLQAALAAGERVVLGQVGLFADGVAVAQIGEHTFELCRHYVDEVVTVST 274
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446551549 263 GELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDPYIKGKKVVAVISGGNVDLQRISSVCEQ 325
Cdd:PRK12483 275 DELCAAIKDIYDDTRSITEPAGALAVAGIKKYAEREGIEGQTLVAIDSGANVNFDRLRHVAER 337
|
|
| PALP |
pfam00291 |
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate ... |
25-281 |
4.39e-66 |
|
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Pssm-ID: 459749 [Multi-domain] Cd Length: 295 Bit Score: 209.86 E-value: 4.39e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 25 RKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGIALSAHLLGIKSKIVM 104
Cdd:pfam00291 6 GPTPLVRLPRLSKELGVDVYLKLESLNPTGSFKDRGALNLLLRLKEGEGGKTVVEASSGNHGRALAAAAARLGLKVTIVV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 105 PISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGE-TYLHPYDDVEVMAGQGTIGLDILDDMW-DVDTVIVPI 182
Cdd:pfam00291 86 PEDAPPGKLLLMRALGAEVVLVGGDYDEAVAAARELAAEGPGaYYINQYDNPLNIEGYGTIGLEILEQLGgDPDAVVVPV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 183 GGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKI-PGDLTFEVVNELVDDIVTVS 261
Cdd:pfam00291 166 GGGGLIAGIARGLKELGPDVRVIGVEPEGAPALARSLAAGRPVPVPVADTIADGLGVGDePGALALDLLDEYVGEVVTVS 245
|
250 260
....*....|....*....|
gi 446551549 262 EGELEVAMKDLLQRGKAVVE 281
Cdd:pfam00291 246 DEEALEAMRLLARREGIVVE 265
|
|
| ectoine_eutB |
TIGR02991 |
ectoine utilization protein EutB; Members of this protein family are EutB, a predicted ... |
10-316 |
7.13e-62 |
|
ectoine utilization protein EutB; Members of this protein family are EutB, a predicted arylmalonate decarboxylase found in a conserved ectoine utilization operon of species that include Sinorhizobium meliloti 1021 (where it is known to be induced by ectoine), Mesorhizobium loti, Silicibacter pomeroyi, Agrobacterium tumefaciens, and Pseudomonas putida. Members of this family resemble threonine dehydratases.
Pssm-ID: 132036 [Multi-domain] Cd Length: 317 Bit Score: 199.69 E-value: 7.13e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 10 IADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGI 89
Cdd:TIGR02991 3 LQDIERAAARISGRVEETPLVESPSLSELCGVPVHLKLEHRQTTGSFKLRGATNAVLSLSDTQRAAGVVAASTGNHGRAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 90 ALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDIL 169
Cdd:TIGR02991 83 AYAAAEEGVRATICMSELVPQNKVDEIRRLGAEVRIVGRSQDDAQEEVERLVADRGLTMLPPFDHPDIVAGQGTLGLEVV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 170 DDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIAD--GCAVKIPGDLTF 247
Cdd:TIGR02991 163 EQMPDLATVLVPLSGGGLASGVAMAVKAARPDTRVIGVSMERGAAMKASLQAGRPVLVAELPTLADslGGGIGLDNRVTF 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446551549 248 EVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDpyIKGKKVVaVISGGNVDL 316
Cdd:TIGR02991 243 AMCKALLDEIVLVSEAEIAAGIRHAYAEEREIVEGAGAVGIAALLAGKIK--NPGPCAV-IVSGRNIDM 308
|
|
| PLN02550 |
PLN02550 |
threonine dehydratase |
18-324 |
1.54e-55 |
|
threonine dehydratase
Pssm-ID: 178165 [Multi-domain] Cd Length: 591 Bit Score: 190.13 E-value: 1.54e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 18 NILDRN----ARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGIALSA 93
Cdd:PLN02550 97 NILSAKvydvAIESPLQLAKKLSERLGVKVLLKREDLQPVFSFKLRGAYNMMAKLPKEQLDKGVICSSAGNHAQGVALSA 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 94 HLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDILDDMW 173
Cdd:PLN02550 177 QRLGCDAVIAMPVTTPEIKWQSVERLGATVVLVGDSYDEAQAYAKQRALEEGRTFIPPFDHPDVIAGQGTVGMEIVRQHQ 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 174 D-VDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIPGDLTFEVVNE 252
Cdd:PLN02550 257 GpLHAIFVPVGGGGLIAGIAAYVKRVRPEVKIIGVEPSDANAMALSLHHGERVMLDQVGGFADGVAVKEVGEETFRLCRE 336
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446551549 253 LVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDPYIKGKKVVAVISGGNVDLQRISSVCE 324
Cdd:PLN02550 337 LVDGVVLVSRDAICASIKDMFEEKRSILEPAGALALAGAEAYCKYYGLKDENVVAITSGANMNFDRLRIVTE 408
|
|
| PRK08813 |
PRK08813 |
threonine dehydratase; Provisional |
10-315 |
3.31e-54 |
|
threonine dehydratase; Provisional
Pssm-ID: 236339 [Multi-domain] Cd Length: 349 Bit Score: 180.98 E-value: 3.31e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 10 IADIKKAQNILDRNARKTPLvksfYLTSKTGgeIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIACSAGNHAQGI 89
Cdd:PRK08813 23 VADVLAAQARLRRYLSPTPL----HYAERFG--VWLKLENLQRTGSYKVRGALNALLAGLERGDERPVICASAGNHAQGV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 90 ALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDIL 169
Cdd:PRK08813 97 AWSAYRLGVQAITVMPHGAPQTKIAGVAHWGATVRQHGNSYDEAYAFARELADQNGYRFLSAFDDPDVIAGQGTVGIELA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 170 DDMWDVdtVIVPIGGGGIISGIAVALKSfnPSINIIGVQAENVHGMkASYDKGTIVEHYEAPTIADGCAVKIPGDLTFEV 249
Cdd:PRK08813 177 AHAPDV--VIVPIGGGGLASGVALALKS--QGVRVVGAQVEGVDSM-ARAIRGDLREIAPVATLADGVKVKIPGFLTRRL 251
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446551549 250 VNELVDDIVTVSEGELEVAMKDLlqrgkaVVEGAGALATAALLAGKVDPYIKGKKVVAVISGGNVD 315
Cdd:PRK08813 252 CSSLLDDVVIVREAELRETLVRL------ALEEHVIAEGAGALALAAGRRVSGKRKCAVVSGGNID 311
|
|
| PRK08246 |
PRK08246 |
serine/threonine dehydratase; |
11-315 |
4.10e-51 |
|
serine/threonine dehydratase;
Pssm-ID: 181319 [Multi-domain] Cd Length: 310 Bit Score: 171.68 E-value: 4.10e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 11 ADIKKAQNILDRNARKTPLVKSfYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMsqLTDQEKDRGVIACSAGNHAQGIA 90
Cdd:PRK08246 8 SDVRAAAQRIAPHIRRTPVLEA-DGAGFGPAPVWLKLEHLQHTGSFKARGAFNRL--LAAPVPAAGVVAASGGNAGLAVA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 91 LSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDILD 170
Cdd:PRK08246 85 YAAAALGVPATVFVPETAPPAKVARLRALGAEVVVVGAEYADALEAAQAFAAETGALLCHAYDQPEVLAGAGTLGLEIEE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 171 DMWDVDTVivpiggggiisGIAV--------ALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIP 242
Cdd:PRK08246 165 QAPGVDTV-----------LVAVggggliagIAAWFEGRARVVAVEPEGAPTLHAALAAGEPVDVPVSGIAADSLGARRV 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446551549 243 GDLTFEVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDPyIKGKKVVAVISGGNVD 315
Cdd:PRK08246 234 GEIAFALARAHVVTSVLVSDEAIIAARRALWEELRLAVEPGAATALAALLSGAYVP-APGERVAVVLCGANTD 305
|
|
| Trp-synth-beta_II |
cd00640 |
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP) ... |
27-312 |
3.50e-50 |
|
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan synthase beta chain (Trp-synth_B), cystathionine beta-synthase (CBS), O-acetylserine sulfhydrylase (CS), serine dehydratase (Ser-dehyd), threonine dehydratase (Thr-dehyd), diaminopropionate ammonia lyase (DAL), and threonine synthase (Thr-synth). ACCD catalyzes the conversion of 1-aminocyclopropane-1-carboxylate to alpha-ketobutyrate and ammonia. Tryptophan synthase folds into a tetramer, where the beta chain is the catalytic PLP-binding subunit and catalyzes the formation of L-tryptophan from indole and L-serine. CBS is a tetrameric hemeprotein that catalyzes condensation of serine and homocysteine to cystathionine. CS is a homodimer that catalyzes the formation of L-cysteine from O-acetyl-L-serine. Ser-dehyd catalyzes the conversion of L- or D-serine to pyruvate and ammonia. Thr-dehyd is active as a homodimer and catalyzes the conversion of L-threonine to 2-oxobutanoate and ammonia. DAL is also a homodimer and catalyzes the alpha, beta-elimination reaction of both L- and D-alpha, beta-diaminopropionate to form pyruvate and ammonia. Thr-synth catalyzes the formation of threonine and inorganic phosphate from O-phosphohomoserine.
Pssm-ID: 107202 [Multi-domain] Cd Length: 244 Bit Score: 167.31 E-value: 3.50e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 27 TPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRG--VIACSAGNHAQGIALSAHLLGIKSKIVM 104
Cdd:cd00640 1 TPLVRLKRLSKLGGANIYLKLEFLNPTGSFKDRGALNLILLAEEEGKLPKgvIIESTGGNTGIALAAAAARLGLKCTIVM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 105 PISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGE-TYLHPYDDVEVMAGQGTIGLDILDDMWD--VDTVivp 181
Cdd:cd00640 81 PEGASPEKVAQMRALGAEVVLVPGDFDDAIALAKELAEEDPGaYYVNQFDNPANIAGQGTIGLEILEQLGGqkPDAV--- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 182 iggggiisGIAV-----------ALKSFNPSINIIGVQAEnvhgmkasydkgtivehyeaptiadgcavkipgdltfevv 250
Cdd:cd00640 158 --------VVPVggggniagiarALKELLPNVKVIGVEPE---------------------------------------- 189
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446551549 251 nelvddIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDPyIKGKKVVAVISGG 312
Cdd:cd00640 190 ------VVTVSDEEALEAIRLLAREEGILVEPSSAAALAAALKLAKKL-GKGKTVVVILTGG 244
|
|
| PRK06608 |
PRK06608 |
serine/threonine dehydratase; |
6-331 |
1.62e-46 |
|
serine/threonine dehydratase;
Pssm-ID: 235842 [Multi-domain] Cd Length: 338 Bit Score: 160.71 E-value: 1.62e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 6 LPLHIADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEK--DRgVIACSAG 83
Cdd:PRK06608 3 LLQNPQNIAAAHNRIKQYLHLTPIVHSESLNEMLGHEIFFKVESLQKTGAFKVRGVLNHLLELKEQGKlpDK-IVAYSTG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 84 NHAQGIALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYgETFDDAKAKCEEiIRETGETYLHPYDDVEVMAGQGT 163
Cdd:PRK06608 82 NHGQAVAYASKLFGIKTRIYLPLNTSKVKQQAALYYGGEVILT-NTRQEAEEKAKE-DEEQGFYYIHPSDSDSTIAGAGT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 164 IGLDILDDM-WDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAP-TIADGCAVKI 241
Cdd:PRK06608 160 LCYEALQQLgFSPDAIFASCGGGGLISGTYLAKELISPTSLLIGSEPLNANDAYLSLKNNKIYRLNYSPnTIADGLKTLS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 242 PGDLTFEVVNELvDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAAllagkVDPYIKG----KKVVAVISGGNVDLQ 317
Cdd:PRK06608 240 VSARTFEYLKKL-DDFYLVEEYEIYYWTAWLTHLLKVICEPSSAINMVA-----VVNWLKTqskpQKLLVILSGGNIDPI 313
|
330
....*....|....
gi 446551549 318 RISSVCEQFFVANE 331
Cdd:PRK06608 314 LYNELWKEDYLTIP 327
|
|
| PRK06110 |
PRK06110 |
threonine dehydratase; |
11-322 |
5.09e-36 |
|
threonine dehydratase;
Pssm-ID: 235699 Cd Length: 322 Bit Score: 132.43 E-value: 5.09e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 11 ADIKKAQNILDRNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKD-RGVIACSAGNHAQGI 89
Cdd:PRK06110 6 AELEAAAAVVYAAMPPTPQYRWPLLAERLGCEVWVKHENHTPTGAFKVRGGLVYFDRLARRGPRvRGVISATRGNHGQSV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 90 ALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKakcEEIIRETGETYLH--PYDDVEVMAGQGTIGLD 167
Cdd:PRK06110 86 AFAARRHGLAATIVVPHGNSVEKNAAMRALGAELIEHGEDFQAAR---EEAARLAAERGLHmvPSFHPDLVRGVATYALE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 168 ILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIPGDLTF 247
Cdd:PRK06110 163 LFRAVPDLDVVYVPIGMGSGICGAIAARDALGLKTRIVGVVSAHAPAYALSFEAGRVVTTPVATTLADGMACRTPDPEAL 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446551549 248 EVVNELVDDIVTVSEGELEVAMKDLLQRGKAVVEGAGALATAALLAGKvdPYIKGKKVVAVISGGNVDLQRISSV 322
Cdd:PRK06110 243 EVIRAGADRIVRVTDDEVAAAMRAYFTDTHNVAEGAGAAALAAALQER--ERLAGKRVGLVLSGGNIDRAVFARV 315
|
|
| L-Ser-dehyd |
cd06448 |
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the ... |
26-261 |
5.73e-25 |
|
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- , D-serine, or L-threonine to pyruvate/ketobutyrate and ammonia.
Pssm-ID: 107209 Cd Length: 316 Bit Score: 102.38 E-value: 5.73e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 26 KTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQ--EKDRGVIACSAGNHAQGIALSAHLLGIKSKIV 103
Cdd:cd06448 1 KTPLIESTALSKTAGCNVFLKLENLQPSGSFKIRGIGHLCQKSAKQglNECVHVVCSSGGNAGLAAAYAARKLGVPCTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 104 MPISAPLAKVEATRGYGSEVVLYGET-FDDAKAKCEEII-RETGETYLHPYDDVEVMAGQGTIGLDILDDMWDVDTVivp 181
Cdd:cd06448 81 VPESTKPRVVEKLRDEGATVVVHGKVwWEADNYLREELAeNDPGPVYVHPFDDPLIWEGHSSMVDEIAQQLQSQEKV--- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 182 iggggiisgIAVAL----------------KSFNPSINIIGVQAENVHGMKASYDKGTIVEHYEAPTIADGCAVKIPGDL 245
Cdd:cd06448 158 ---------DAIVCsvggggllngivqgleRNGWGDIPVVAVETEGAHSLNASLKAGKLVTLPKITSVATSLGAKTVSSQ 228
|
250 260
....*....|....*....|..
gi 446551549 246 TFE------VVNELVDDIVTVS 261
Cdd:cd06448 229 ALEyaqehnIKSEVVSDRDAVQ 250
|
|
| Thr-synth_1 |
cd01563 |
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last ... |
27-272 |
3.45e-19 |
|
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants, OPH is an intermediate between the methionine and threonine/isoleucine pathways. Thus threonine synthase competes for OPH with cystathionine-gamma-synthase, the first enzyme in the methionine pathway. These enzymes are in general dimers. Members of this CD, Thr-synth_1, are widely distributed in bacteria, archaea and higher plants.
Pssm-ID: 107206 [Multi-domain] Cd Length: 324 Bit Score: 86.49 E-value: 3.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 27 TPLVKSFYLTSKTGG-EIHLKLENMQLTGSFKFRGAFNKMSQLTdQEKDRGVIACSAGNHAQGIALSAHLLGIKSKIVMP 105
Cdd:cd01563 23 TPLVRAPRLGERLGGkNLYVKDEGLNPTGSFKDRGMTVAVSKAK-ELGVKAVACASTGNTSASLAAYAARAGIKCVVFLP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 106 ISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETG---ETYLHPYdDVEvmaGQGTIGLDILDDM-WDV-DTVIV 180
Cdd:cd01563 102 AGKALGKLAQALAYGATVLAVEGNFDDALRLVRELAEENWiylSNSLNPY-RLE---GQKTIAFEIAEQLgWEVpDYVVV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 181 PIGGGGIISGIAVALKSF--------NPSinIIGVQAEN----VHGMKASYDKGTIVEHyeAPTIADGCAVKIP--GDLT 246
Cdd:cd01563 178 PVGNGGNITAIWKGFKELkelglidrLPR--MVGVQAEGaapiVRAFKEGKDDIEPVEN--PETIATAIRIGNPasGPKA 253
|
250 260
....*....|....*....|....*.
gi 446551549 247 FEVVNELVDDIVTVSEGELEVAMKDL 272
Cdd:cd01563 254 LRAVRESGGTAVAVSDEEILEAQKLL 279
|
|
| CBS_like |
cd01561 |
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS ... |
26-275 |
7.56e-18 |
|
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.
Pssm-ID: 107204 [Multi-domain] Cd Length: 291 Bit Score: 82.18 E-value: 7.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 26 KTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNkMsqLTDQEKdRG-------VIACSAGNHAQGIALSAHLLGI 98
Cdd:cd01561 2 NTPLVRLNRLSPGTGAEIYAKLEFFNPGGSVKDRIALY-M--IEDAEK-RGllkpgttIIEPTSGNTGIGLAMVAAAKGY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 99 KSKIVMPISAPLAKVEATRGYGSEVVLY-GETFDDAK---AKCEEIIRETGETY-LHPYD-DVEVMAGQGTIGLDILDDM 172
Cdd:cd01561 78 RFIIVMPETMSEEKRKLLRALGAEVILTpEAEADGMKgaiAKARELAAETPNAFwLNQFEnPANPEAHYETTAPEIWEQL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 173 -WDVDTVivpiggggiisgiaVA--------------LKSFNPSINIIGVQAENvhgmKASYDKGTIVEHyeaptiadgc 237
Cdd:cd01561 158 dGKVDAF--------------VAgvgtggtitgvaryLKEKNPNVRIVGVDPVG----SVLFSGGPPGPH---------- 209
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 446551549 238 avKIPG---DLTFEVVN-ELVDDIVTVSEGELEVAMKDLLQR 275
Cdd:cd01561 210 --KIEGigaGFIPENLDrSLIDEVVRVSDEEAFAMARRLARE 249
|
|
| CysK |
COG0031 |
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the ... |
14-275 |
2.15e-15 |
|
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the Pathway/BioSystem: Cysteine biosynthesis
Pssm-ID: 439802 [Multi-domain] Cd Length: 301 Bit Score: 75.47 E-value: 2.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 14 KKAQNILDRNARkTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNkMsqLTDQEKdRG-------VIACSAGNha 86
Cdd:COG0031 2 RIYDSILELIGN-TPLVRLNRLSPGPGAEIYAKLESFNPGGSVKDRIALS-M--IEDAEK-RGllkpggtIVEATSGN-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 87 QGIALS--AHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLY--GETFDDAKAKCEEIIRETGETYlhpyddvevMAGQ- 161
Cdd:COG0031 75 TGIGLAmvAAAKGYRLILVMPETMSKERRALLRAYGAEVVLTpgAEGMKGAIDKAEELAAETPGAF---------WPNQf 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 162 ----------GTIGLDILDDMW-DVDTVivpiggggiisgiaVA--------------LKSFNPSINIIGVQAENvhgmK 216
Cdd:COG0031 146 enpanpeahyETTGPEIWEQTDgKVDAF--------------VAgvgtggtitgvgryLKERNPDIKIVAVEPEG----S 207
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446551549 217 ASYDKGTIVEHyeaptiadgcavKIPG---DLTFEVVN-ELVDDIVTVSEGELEVAMKDLLQR 275
Cdd:COG0031 208 PLLSGGEPGPH------------KIEGigaGFVPKILDpSLIDEVITVSDEEAFAMARRLARE 258
|
|
| ThrC |
COG0498 |
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the ... |
27-275 |
1.55e-13 |
|
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 440264 [Multi-domain] Cd Length: 394 Bit Score: 70.61 E-value: 1.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 27 TPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLtdQEKDRGVIAC-SAGNHAQGIALSAHLLGIKSKIVMP 105
Cdd:COG0498 67 TPLVKAPRLADELGKNLYVKEEGHNPTGSFKDRAMQVAVSLA--LERGAKTIVCaSSGNGSAALAAYAARAGIEVFVFVP 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 106 IS-APLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGeTYL----HPYddveVMAGQGTIGLDILDDMWDV-DTVI 179
Cdd:COG0498 145 EGkVSPGQLAQMLTYGAHVIAVDGNFDDAQRLVKELAADEG-LYAvnsiNPA----RLEGQKTYAFEIAEQLGRVpDWVV 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 180 VPiggggiisgiaV--------ALKSFN-----------PSinIIGVQAENVHGMKASYDKGTivEHYE---APTIADGC 237
Cdd:COG0498 220 VP-----------TgnggnilaGYKAFKelkelglidrlPR--LIAVQATGCNPILTAFETGR--DEYEperPETIAPSM 284
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 446551549 238 AVKIPGDLtFEVVNELVD---DIVTVSEGELEVAMKDLLQR 275
Cdd:COG0498 285 DIGNPSNG-ERALFALREsggTAVAVSDEEILEAIRLLARR 324
|
|
| PRK05638 |
PRK05638 |
threonine synthase; Validated |
27-311 |
4.56e-11 |
|
threonine synthase; Validated
Pssm-ID: 235539 [Multi-domain] Cd Length: 442 Bit Score: 63.29 E-value: 4.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 27 TPLVKSfYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIAcSAGNHAQGIALSAHLLGIKSKIVMPI 106
Cdd:PRK05638 67 TPLIRA-RISEKLGENVYIKDETRNPTGSFRDRLATVAVSYGLPYAANGFIVA-SDGNAAASVAAYSARAGKEAFVVVPR 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 107 SAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETYLHPYDDVEVMAGQGTIGLDILDDMWDVDTVIVPIGGGG 186
Cdd:PRK05638 145 KVDKGKLIQMIAFGAKIIRYGESVDEAIEYAEELARLNGLYNVTPEYNIIGLEGQKTIAFELWEEINPTHVIVPTGSGSY 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 187 IISGiavaLKSFNPSINI---------IGVQAEN-------VHGMKASYDkgtivehyeaPTIADGCAVKIPgdLTFEVV 250
Cdd:PRK05638 225 LYSI----YKGFKELLEIgvieeipklIAVQTERcnpiaseILGNKTKCN----------ETKALGLYVKNP--VMKEYV 288
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446551549 251 NELVDD----IVTVSEGELEVAMKDLLQRGkAVVEGAGALATAALLAGKVDPYI-KGKKVVAVISG 311
Cdd:PRK05638 289 SEAIKEsggtAVVVNEEEIMAGEKLLAKEG-IFAELSSAVVMPALLKLGEEGYIeKGDKVVLVVTG 353
|
|
| PRK08197 |
PRK08197 |
threonine synthase; Validated |
27-175 |
4.66e-09 |
|
threonine synthase; Validated
Pssm-ID: 181283 [Multi-domain] Cd Length: 394 Bit Score: 56.93 E-value: 4.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 27 TPLVKSFYLTSKTG-GEIHLKLENMQLTGSFKFRGAFNKMSQltdqEKDRGV--IAC-SAGNHAQGIALSAHLLGIKSKI 102
Cdd:PRK08197 80 TPLLPLPRLGKALGiGRLWVKDEGLNPTGSFKARGLAVGVSR----AKELGVkhLAMpTNGNAGAAWAAYAARAGIRATI 155
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446551549 103 VMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETG----ETYLHPYdDVEvmaGQGTIGLDILDDM-WDV 175
Cdd:PRK08197 156 FMPADAPEITRLECALAGAELYLVDGLISDAGKIVAEAVAEYGwfdvSTLKEPY-RIE---GKKTMGLELAEQLgWRL 229
|
|
| PRK06381 |
PRK06381 |
threonine synthase; Validated |
21-175 |
4.88e-09 |
|
threonine synthase; Validated
Pssm-ID: 235789 Cd Length: 319 Bit Score: 56.64 E-value: 4.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 21 DRNARKTPLVKSFYLTSKTG-GEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDrGVIACSAGNHAQGIALSAHLLGIK 99
Cdd:PRK06381 10 EKPPGGTPLLRARKLEEELGlRKIYLKFEGANPTGTQKDRIAEAHVRRAMRLGYS-GITVGTCGNYGASIAYFARLYGLK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 100 SKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGeTY------LHPYDDVEvmaGQGTIGLDILDDMW 173
Cdd:PRK06381 89 AVIFIPRSYSNSRVKEMEKYGAEIIYVDGKYEEAVERSRKFAKENG-IYdanpgsVNSVVDIE---AYSAIAYEIYEALG 164
|
..
gi 446551549 174 DV 175
Cdd:PRK06381 165 DV 166
|
|
| cysM |
PRK11761 |
cysteine synthase CysM; |
26-125 |
1.07e-08 |
|
cysteine synthase CysM;
Pssm-ID: 236972 Cd Length: 296 Bit Score: 55.65 E-value: 1.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 26 KTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNkMSQltdQEKDRGVI--------ACSaGNhaQGIALS--AHL 95
Cdd:PRK11761 12 NTPLVKLQRLPPDRGNTILAKLEGNNPAGSVKDRPALS-MIV---QAEKRGEIkpgdtlieATS-GN--TGIALAmiAAI 84
|
90 100 110
....*....|....*....|....*....|
gi 446551549 96 LGIKSKIVMPISAPLAKVEATRGYGSEVVL 125
Cdd:PRK11761 85 KGYRMKLIMPENMSQERRAAMRAYGAELIL 114
|
|
| PRK06450 |
PRK06450 |
threonine synthase; Validated |
27-139 |
5.39e-08 |
|
threonine synthase; Validated
Pssm-ID: 180565 [Multi-domain] Cd Length: 338 Bit Score: 53.59 E-value: 5.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 27 TPLVKsfyltsktGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQeKDRGVIACSAGNHAQGIALSAHLLGIKSKIVMPI 106
Cdd:PRK06450 59 TPLIK--------KGNIWFKLDFLNPTGSYKDRGSVTLISYLAEK-GIKQISEDSSGNAGASIAAYGAAAGIEVKIFVPE 129
|
90 100 110
....*....|....*....|....*....|...
gi 446551549 107 SAPLAKVEATRGYGSEVVLYGETFDDAKAKCEE 139
Cdd:PRK06450 130 TASGGKLKQIESYGAEVVRVRGSREDVAKAAEN 162
|
|
| PRK08206 |
PRK08206 |
diaminopropionate ammonia-lyase; Provisional |
8-172 |
2.22e-07 |
|
diaminopropionate ammonia-lyase; Provisional
Pssm-ID: 236186 Cd Length: 399 Bit Score: 51.80 E-value: 2.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 8 LHIADIKKAQNILDR--NARKTPLVKSFYLTSKTG-GEIHLKLENMQL-TGSFKFRGA-----------FNK------MS 66
Cdd:PRK08206 24 LSQEEAKKARAFHQSfpGYAPTPLVALPDLAAELGvGSILVKDESYRFgLNAFKALGGayavarllaekLGLdiselsFE 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 67 QLTDQEK-----DRGVIACSAGNHAQGIALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEII 141
Cdd:PRK08206 104 ELTSGEVreklgDITFATATDGNHGRGVAWAAQQLGQKAVIYMPKGSSEERVDAIRALGAECIITDGNYDDSVRLAAQEA 183
|
170 180 190
....*....|....*....|....*....|....*...
gi 446551549 142 RETG-----ETYLHPYDDV--EVMAGQGTIGLDILDDM 172
Cdd:PRK08206 184 QENGwvvvqDTAWEGYEEIptWIMQGYGTMADEAVEQL 221
|
|
| PRK10717 |
PRK10717 |
cysteine synthase A; Provisional |
27-125 |
1.27e-06 |
|
cysteine synthase A; Provisional
Pssm-ID: 182672 [Multi-domain] Cd Length: 330 Bit Score: 49.47 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 27 TPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNkMSQltDQEKdRG-------VIACSAGNHAQGIALSAHLLGIK 99
Cdd:PRK10717 14 TPLIRLNRASEATGCEILGKAEFLNPGGSVKDRAALN-IIW--DAEK-RGllkpggtIVEGTAGNTGIGLALVAAARGYK 89
|
90 100
....*....|....*....|....*.
gi 446551549 100 SKIVMPISAPLAKVEATRGYGSEVVL 125
Cdd:PRK10717 90 TVIVMPETQSQEKKDLLRALGAELVL 115
|
|
| PLN03013 |
PLN03013 |
cysteine synthase |
18-208 |
6.19e-06 |
|
cysteine synthase
Pssm-ID: 178587 [Multi-domain] Cd Length: 429 Bit Score: 47.46 E-value: 6.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 18 NILDRNAR---KTPLVksfYLTSKTGG---EIHLKLENMQLTGSFKFRGAFnkmSQLTDQEKdRGVIAC--------SAG 83
Cdd:PLN03013 112 NIADNVSQligKTPMV---YLNSIAKGcvaNIAAKLEIMEPCCSVKDRIGY---SMVTDAEQ-KGFISPgksvlvepTSG 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 84 NHAQGIALSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLY--GETFDDAKAKCEEIIRETGETY-LHPYDD-VEVMA 159
Cdd:PLN03013 185 NTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTdpAKGMTGAVQKAEEILKNTPDAYmLQQFDNpANPKI 264
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446551549 160 GQGTIGLDILDDM-WDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQ 208
Cdd:PLN03013 265 HYETTGPEIWDDTkGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVE 314
|
|
| PLN02556 |
PLN02556 |
cysteine synthase/L-3-cyanoalanine synthase |
26-208 |
7.61e-06 |
|
cysteine synthase/L-3-cyanoalanine synthase
Pssm-ID: 178171 [Multi-domain] Cd Length: 368 Bit Score: 47.26 E-value: 7.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 26 KTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFnkmSQLTDQEKDR-------GVIACSAGNHAQGIALSAHLLGI 98
Cdd:PLN02556 59 KTPLVYLNKVTEGCGAYIAAKQEMFQPTSSIKDRPAL---AMIEDAEKKNlitpgktTLIEPTSGNMGISLAFMAAMKGY 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 99 KSKIVMPISAPLAKVEATRGYGSEVVLYGET--FDDAKAKCEEIIRETGETY-LHPYDD-VEVMAGQGTIGLDILDD-MW 173
Cdd:PLN02556 136 KMILTMPSYTSLERRVTMRAFGAELVLTDPTkgMGGTVKKAYELLESTPDAFmLQQFSNpANTQVHFETTGPEIWEDtLG 215
|
170 180 190
....*....|....*....|....*....|....*
gi 446551549 174 DVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQ 208
Cdd:PLN02556 216 QVDIFVMGIGSGGTVSGVGKYLKSKNPNVKIYGVE 250
|
|
| PRK08329 |
PRK08329 |
threonine synthase; Validated |
12-178 |
9.44e-06 |
|
threonine synthase; Validated
Pssm-ID: 236244 [Multi-domain] Cd Length: 347 Bit Score: 46.74 E-value: 9.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 12 DIKKAQNILDRNARKTP-LVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKMSQLTDQEKDRGVIAcSAGNHAQGIA 90
Cdd:PRK08329 42 DMRRYIDYLPVDEEFLPhLTPPITPTVKRSIKVYFKLDYLQPTGSFKDRGTYVTVAKLKEEGINEVVID-SSGNAALSLA 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 91 LSAHLLGIKSKIVMPISAPLAKVEATRGYGSEVVLYGETFDDAKAKCEEIIRETGETY----LHPYddveVMAGQGTIGL 166
Cdd:PRK08329 121 LYSLSEGIKVHVFVSYNASKEKISLLSRLGAELHFVEGDRMEVHEEAVKFSKRNNIPYvshwLNPY----FLEGTKTIAY 196
|
170
....*....|..
gi 446551549 167 DILDDMWDVDTV 178
Cdd:PRK08329 197 EIYEQIGVPDYA 208
|
|
| PLN02565 |
PLN02565 |
cysteine synthase |
26-208 |
5.63e-05 |
|
cysteine synthase
Pssm-ID: 166206 Cd Length: 322 Bit Score: 44.14 E-value: 5.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 26 KTPLVksfYLTSKTGG---EIHLKLENMQLTGSFKFRGAFnkmSQLTDQEKdRGVIAC--------SAGNHAQGIALSAH 94
Cdd:PLN02565 15 KTPLV---YLNNVVDGcvaRIAAKLEMMEPCSSVKDRIGY---SMITDAEE-KGLIKPgesvliepTSGNTGIGLAFMAA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 95 LLGIKSKIVMPISAPLAKVEATRGYGSEVVLY--GETFDDAKAKCEEIIRETGETYL--------HP---YDDVEVMAGQ 161
Cdd:PLN02565 88 AKGYKLIITMPASMSLERRIILLAFGAELVLTdpAKGMKGAVQKAEEILAKTPNSYIlqqfenpaNPkihYETTGPEIWK 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446551549 162 GTIGldilddmwDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQ 208
Cdd:PLN02565 168 GTGG--------KVDAFVSGIGTGGTITGAGKYLKEQNPDIKLYGVE 206
|
|
| PRK13803 |
PRK13803 |
bifunctional phosphoribosylanthranilate isomerase/tryptophan synthase subunit beta; Provisional |
13-104 |
4.23e-03 |
|
bifunctional phosphoribosylanthranilate isomerase/tryptophan synthase subunit beta; Provisional
Pssm-ID: 237513 [Multi-domain] Cd Length: 610 Bit Score: 39.02 E-value: 4.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446551549 13 IKKAQNILDRNA-RKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRgafNKMSQ--LTDQEKDRGVIA-CSAGNHAQG 88
Cdd:PRK13803 257 QKTFKRLLQNYAgRPTPLTEAKRLSDIYGARIYLKREDLNHTGSHKIN---NALGQalLAKRMGKTRIIAeTGAGQHGVA 333
|
90
....*....|....*.
gi 446551549 89 IALSAHLLGIKSKIVM 104
Cdd:PRK13803 334 TATACALFGLKCTIFM 349
|
|
| |
