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Conserved domains on  [gi|446554052|ref|WP_000631398|]
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MULTISPECIES: GNAT family N-acetyltransferase [Bacillus]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10456837)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  15581578|10940244|9175471|27367672|26818562
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 32-143 2.49e-16

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


:

Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 70.24  E-value: 2.49e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052   32 NWSEDEAVNLSKIEFDQLLPKGEKTEYNYLYSIFHDQNLVGMIWIAQKSPTSNEeGFIYDFIIFEQYQGLGYGKKAMKEI 111
Cdd:pfam00583   6 ELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDDEPPV-GEIEGLAVAPEYRGKGIGTALLQAL 84

                          90       100       110
                  ....*....|....*....|....*....|..
gi 446554052  112 EVIAKELGMKKIGLHVFGHNKVARGLYEKLGY 143
Cdd:pfam00583  85 LEWARERGCERIFLEVAADNLAAIALYEKLGF 116
 
Name Accession Description Interval E-value
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 32-143 2.49e-16

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 70.24  E-value: 2.49e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052   32 NWSEDEAVNLSKIEFDQLLPKGEKTEYNYLYSIFHDQNLVGMIWIAQKSPTSNEeGFIYDFIIFEQYQGLGYGKKAMKEI 111
Cdd:pfam00583   6 ELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDDEPPV-GEIEGLAVAPEYRGKGIGTALLQAL 84

                          90       100       110
                  ....*....|....*....|....*....|..
gi 446554052  112 EVIAKELGMKKIGLHVFGHNKVARGLYEKLGY 143
Cdd:pfam00583  85 LEWARERGCERIFLEVAADNLAAIALYEKLGF 116
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 72-146 3.23e-15

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 66.60  E-value: 3.23e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554052  72 GMIWIAQksPTSNEEGFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHNKVARGLYEKLGYEIT 146
Cdd:COG0456    1 GFALLGL--VDGGDEAEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGFEEV 73
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 61-126 9.78e-10

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 51.51  E-value: 9.78e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446554052  61 LYSIFHDQNLVGMIWIAqKSPTSNEEGFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLH 126
Cdd:cd04301    1 FLVAEDDGEIVGFASLS-PDGSGGDTAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
PRK03624 PRK03624
putative acetyltransferase; Provisional
 87-144 3.57e-06

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 43.76  E-value: 3.57e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446554052  87 GFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHNKVARGLYEKLGYE 144
Cdd:PRK03624  69 GWAYYLAVHPDFRGRGIGRALVARLEKKLIARGCPKINLQVREDNDAVLGFYEALGYE 126
 
Name Accession Description Interval E-value
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 32-143 2.49e-16

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 70.24  E-value: 2.49e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052   32 NWSEDEAVNLSKIEFDQLLPKGEKTEYNYLYSIFHDQNLVGMIWIAQKSPTSNEeGFIYDFIIFEQYQGLGYGKKAMKEI 111
Cdd:pfam00583   6 ELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDDEPPV-GEIEGLAVAPEYRGKGIGTALLQAL 84

                          90       100       110
                  ....*....|....*....|....*....|..
gi 446554052  112 EVIAKELGMKKIGLHVFGHNKVARGLYEKLGY 143
Cdd:pfam00583  85 LEWARERGCERIFLEVAADNLAAIALYEKLGF 116
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 72-146 3.23e-15

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 66.60  E-value: 3.23e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554052  72 GMIWIAQksPTSNEEGFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHNKVARGLYEKLGYEIT 146
Cdd:COG0456    1 GFALLGL--VDGGDEAEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGFEEV 73
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 1-146 5.88e-12

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 60.01  E-value: 5.88e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052   1 MITLKPMAEEEFQRYYENEIEDYAKEKVAAGNWSEDEAVNLskieFDQLLPKGEKTEYnYLYSIFH--DQNLVGMIWIAQ 78
Cdd:COG1670    7 RLRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAW----LERLLADWADGGA-LPFAIEDkeDGELIGVVGLYD 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554052  79 KSPTsNEEGFIyDFIIFEQYQGLGYGKKAMKE-IEVIAKELGMKKIGLHVFGHNKVARGLYEKLGYEIT 146
Cdd:COG1670   82 IDRA-NRSAEI-GYWLAPAYWGKGYATEALRAlLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLE 148
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
70-144 3.10e-10

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 53.37  E-value: 3.10e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554052  70 LVGMIWIAQKSPTSNEEGFIYdfiIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHNKVARGLYEKLGYE 144
Cdd:COG3393    2 LVAMAGVRAESPGVAEISGVY---THPEYRGRGLASALVAALAREALARGARTPFLYVDADNPAARRLYERLGFR 73
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 34-146 6.80e-10

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 53.90  E-value: 6.80e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052  34 SEDEAVNLSKIEFDQLLPKGEKTEYNYLYSIFHDQN-LVGMIWIaqkSPTSNEEGFIYDFIIFEQYQGLGYGKKAMKEIE 112
Cdd:COG0454    8 PEDINFILLIEALDAELKAMEGSLAGAEFIAVDDKGePIGFAGL---RRLDDKVLELKRLYVLPEYRGKGIGKALLEALL 84

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446554052 113 VIAKELGMKKIGLHVFGHNKVARGLYEKLGYEIT 146
Cdd:COG0454   85 EWARERGCTALELDTLDGNPAAIRFYERLGFKEI 118
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
67-146 8.30e-10

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 54.23  E-value: 8.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052  67 DQNLVGMIWIaqkSPTSNEEGF--IYDFIIF--EQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHNKVARGLYEKLG 142
Cdd:COG1247   60 DGEVVGFASL---GPFRPRPAYrgTAEESIYvdPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLG 136


                 ....
gi 446554052 143 YEIT 146
Cdd:COG1247  137 FEEV 140
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 61-126 9.78e-10

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 51.51  E-value: 9.78e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446554052  61 LYSIFHDQNLVGMIWIAqKSPTSNEEGFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLH 126
Cdd:cd04301    1 FLVAEDDGEIVGFASLS-PDGSGGDTAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 57-145 1.19e-08

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 49.38  E-value: 1.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052   57 EYNYLYSIFHDQNLVGMIWIAQKSPTsnEEGFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHnkvARG 136
Cdd:pfam13508   1 PGGRFFVAEDDGKIVGFAALLPLDDE--GALAELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNR---AAA 75


                  ....*....
gi 446554052  137 LYEKLGYEI 145
Cdd:pfam13508  76 FYEKLGFEE 84
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 66-146 1.76e-08

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 49.99  E-value: 1.76e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052  66 HDQNLVGMIWIAqksPTSNEEGFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHnkvARGLYEKLGYEI 145
Cdd:COG1246   35 EDGEIVGCAALH---PLDEDLAELRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLTTSA---AIHFYEKLGFEE 108


                 .
gi 446554052 146 T 146
Cdd:COG1246  109 I 109
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
66-144 1.20e-07

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 48.16  E-value: 1.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052  66 HDQNLVGMIWIAQKSPTSNEE-GFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVfghNKVARGLYEKLGYE 144
Cdd:COG3153   46 DDGEIVGHVALSPVDIDGEGPaLLLGPLAVDPEYRGQGIGRALMRAALEAARERGARAVVLLG---DPSLLPFYERFGFR 122
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
96-154 3.16e-06

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 44.02  E-value: 3.16e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554052  96 EQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHnkvARGLYEKLGYEITN----------IDMMKSI 154
Cdd:COG2153   68 PEYRGQGLGRALMEAAIEEARERGARRIVLSAQAH---AVGFYEKLGFVPVGeefleagiphIDMRKPL 133
PRK03624 PRK03624
putative acetyltransferase; Provisional
 87-144 3.57e-06

putative acetyltransferase; Provisional


Pssm-ID: 235142 [Multi-domain]  Cd Length: 140  Bit Score: 43.76  E-value: 3.57e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446554052  87 GFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHNKVARGLYEKLGYE 144
Cdd:PRK03624  69 GWAYYLAVHPDFRGRGIGRALVARLEKKLIARGCPKINLQVREDNDAVLGFYEALGYE 126
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 19-144 9.49e-06

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 42.64  E-value: 9.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052   19 EIEDYAKEKVAagNWSEDeavnLSKIEFDQLLPKGEkteyNYLYSIFHDQNLVGMIWIAQksptsneEGFIYDFIIFEQY 98
Cdd:pfam13673   1 EAPDYSEEGIE--TFYEF----ISPEALRERIDQGE----YFFFVAFEGGQIVGVIALRD-------RGHISLLFVDPDY 63

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 446554052   99 QGLGYGKKAMKEIEVIAKELGMKKIGLHVFGHNkVARGLYEKLGYE 144
Cdd:pfam13673  64 QGQGIGKALLEAVEDYAEKDGIKLSELTVNASP-YAVPFYEKLGFR 108
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 2-144 1.26e-04

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 39.64  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052    2 ITLKPMAEEEFQRYYENeiedYAKEKVAAGNWSEDEAVNLSKIEFDQLLpKGEKTEYNYLYSIFH-DQNLVGMIWIAQKS 80
Cdd:pfam13302   2 LLLRPLTEEDAEALFEL----LSDPEVMRYGVPWPLTLEEAREWLARIW-AADEAERGYGWAIELkDTGFIGSIGLYDID 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554052   81 PtSNEEGFIyDFIIFEQYQGLGYGKKAMKE-IEVIAKELGMKKIGLHVFGHNKVARGLYEKLGYE 144
Cdd:pfam13302  77 G-EPERAEL-GYWLGPDYWGKGYATEAVRAlLEYAFEELGLPRLVARIDPENTASRRVLEKLGFK 139
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 49-143 6.63e-03

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 34.90  E-value: 6.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554052  49 LLPKGEKTEYN-----YL-YSIFHDQNLVGMIwIAQkspTSNEEGFIYDFIIFEQYQGLGYGKKAMKEIEVIAKELGMKK 122
Cdd:PRK09491  24 AFPWSEKTFASnqgerYLnLKLTVNGQMAAFA-ITQ---VVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVAT 99

                         90       100
                 ....*....|....*....|.
gi 446554052 123 IGLHVFGHNKVARGLYEKLGY 143
Cdd:PRK09491 100 LWLEVRASNAAAIALYESLGF 120
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
 87-144 9.06e-03

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 33.46  E-value: 9.06e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446554052   87 GFIYDFIIFEQYQGLGYGKKAMKEI-EVIAKElgmkkiGLHVFGH----NKVARGLYEKLGYE 144
Cdd:pfam08445  22 GELGALQTLPEHRRRGLGSRLVAALaRGIAER------GITPFAVvvagNTPSRRLYEKLGFR 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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