|
Name |
Accession |
Description |
Interval |
E-value |
| TraC-F-type |
TIGR02746 |
type-IV secretion system protein TraC; The protein family described here is common among the F, ... |
25-811 |
0e+00 |
|
type-IV secretion system protein TraC; The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.
Pssm-ID: 274279 [Multi-domain] Cd Length: 797 Bit Score: 611.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 25 PVLAYDEDDHVFlMDDHSAGFGFMCEPLCGADEKVQERMNGFLNQEFPSKTTLQFVLFRSPDINQEMYRMMGLRDGfRHE 104
Cdd:TIGR02746 3 PYRAYDEESGIF-MNRHSMGFGLELTPLSGADESLVESLSSLLRTDLPEGTDIQVLLWGSPQIGPFLDRNEEQFSQ-NGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 105 LLTSVIKERINFLQHhTTERIFAKTNkgiydNGLIQDLKLFVTCKVPIKNNNptESELQQLAQLRTKVESSLQTVGLRPR 184
Cdd:TIGR02746 81 ILEKLARNRVKYYLN-AAQKGFFKNS-----GVTLRDFRLFLSVSIPFKSPN--EDVIQELRSLRERIESTLRSAGFGCR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 185 TMTAVNYIRIMSTILNWGPDaSWRHDSVDWEMDKPICEQIFDYGTDVEVSKNGI--RLGDYHA------KVMSAKKLPD- 255
Cdd:TIGR02746 153 RVDAEDLLSLVREMLNPDPD-SIHPWPISYDPNQLLRDQIVDPDTDLEVHEGGLevDHEDNQGevktriRVFSIKRFPEe 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 256 --VFYFGDALtyaGDLSGGNSSIKENYMVVTNVFFPEAESTKNTLERKRQFTVNQAYGPMLKFVPVLADKKESFDTLYES 333
Cdd:TIGR02746 232 ftLWQTGNLI---GDLLNPSLQITCPFLLSFTVRVEDQVKKKAKATAKAKDLNKQAKSSMAKWVPSLEKKLKEIKYLREA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 334 -MKEGAKPVKITYSVVLFApTKERVEAAAMAARNIWRESRFELMEDKFVALPMFLNCLPFCTDRDAVRDL---FRYKTMT 409
Cdd:TIGR02746 309 iASGGDSLVSMYYNVLLFT-NPDNLRRDVEAAKSSFRKNGFDLAEDKRIQLQAFLAALPFNPTEGLFEDLkkaGRVRTLS 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 410 TEQAAVVLPVFGEWKGTGTYHAALISRNGQLMSLSLHDSN-TNKNLVIAAESGSGKSFLTNELIFSYLSEGAQVWVIDAG 488
Cdd:TIGR02746 388 SANAVNLLPLIADWKGTKGSGLLLPTRRGQLSAFDPFDSDsTNYNIAVVGGSGAGKSFFMQELIVDNLSRGGKVWVIDVG 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 489 KSYQKLSEMLNGDFVHFEEGTHVCLNPF--ELIQNYEDEEDAIVSLVCAMASAKGLLDEWQISALKQVLSRLWEEKGKEM 566
Cdd:TIGR02746 468 RSYKKLCEMLGGTYIEFSPESNICLNPFtgNNVTEIDDEIDQITALIALMASPEGGLSDEQRSTLEEAILAAWKEYGNEA 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 567 KVDDIAERCLE---EENDQRLKDIGQQLYAFTSKGSYGKYFSRKNNVSFQNQFTVLELDELQGRKHLRQVVLLQLIYQIQ 643
Cdd:TIGR02746 548 TITDVQDALQQledDENDPRIKDLGKMLNPYTSHGVYGRYFNGPNNLDFSNRFVVLELEELEDRPDLQAVVLFSLMVRIT 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 644 QEVFLGERNRKKVVIVDEAWDLL--KEGEVSVFMEHAYRKFRKYGGSVVIATQSINDLYENAVGRAIAENSASMYLLGQT 721
Cdd:TIGR02746 628 GEMYLTPRKRRKICIIDEAWSLLdgANPQAADFIETGYRRARKYGGAFITITQGIEDFYSSPEARAAYANSDWKIILRQS 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 722 EETVESVKRSGRLTLSEGGFHTLKTVHTIQGVYSEIFIKSKSGMGVGRLIVGDFQKLLYSTDPVDVNAIDQFVKQGMSIP 801
Cdd:TIGR02746 708 AESIAKLKAENPFTFSPFEKRLIKSLRTAKGAFSELLIRSGEGSSVHRLFVDPFSRVLFSTDGPEFEEVEELREQGLSLE 787
|
810
....*....|
gi 446560040 802 EAIKAVMRSR 811
Cdd:TIGR02746 788 EAIEQLAQKH 797
|
|
| VirB4 |
COG3451 |
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ... |
238-797 |
3.85e-118 |
|
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442674 [Multi-domain] Cd Length: 546 Bit Score: 368.12 E-value: 3.85e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 238 IRLGDYHAKVMSAKKLPDVFYFG--DALTyagdlsggnsSIKENYMVVTNVFFPEAESTKNTLERKRQFTVNQAYGPMLK 315
Cdd:COG3451 3 LEIGDRYGRVLSIKGYPSETSPGllDPLL----------QLPCEFIVTQSFTPLDKDEALKKLKRKRRRLESKRKSEQAL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 316 FVPVLADKKESFDTLYESMKEG-AKPVKITYSVVLFAPTKERVEAAAMAARNIWRESRFELMEDKFVALPMFLNCLPFCT 394
Cdd:COG3451 73 VDDDAESQAEDAEEALDELQSGgERLGEVHLTLTVFADDLEELEEAVREVESALQSAGFTLVRETLNQEEAFLSSLPGNF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 395 DRDavrdlFRYKTMTTEQAAVVLPVFGEWKGTGTYHAALISRNGQLMSLSLHDSNTNKNLVIAAESGSGKSFLTNELIFS 474
Cdd:COG3451 153 DYR-----LRRRLLTTSNLAALFPFHSFELGDPWGIYLLNTRSGTPVFFDFHDGLDNGNTLILGPSGSGKSFLLKLLLLQ 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 475 YLSEGAQVWVIDAGKSYQKLSEMLNGDFVHFEEGTHVCLNPFELIqNYEDEEDAIVSLVCAMASA-KGLLDEWQISALKQ 553
Cdd:COG3451 228 LLRYGARIVIFDPGGSYEILVRALGGTYIDLSPGSPTGLNPFDLE-DTEEKRDFLLELLELLLGReGEPLTPEERAAIDR 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 554 VLSRLWEEKGKEMK--VDDIAERCleeENDQRLKDIGQQLYAFTSKGSYGKYFSRKNNVSFQ-NQFTVLELDELQGRKHL 630
Cdd:COG3451 307 AVRALYRRADPEERttLSDLYELL---KEQPEAKDLAARLEPYTKGGSYGWLFDGPTNLDLSdARFVVFDLTELLDNPEL 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 631 RQVVLLQLIYQIQQEVFLGERNRKKVVIVDEAWDLLKEGEVSVFMEHAYRKFRKYGGSVVIATQSINDLYENAVGRAIAE 710
Cdd:COG3451 384 RPPVLLYLLHRIWNRLRKNNDGRPTLIVIDEAWLLLDNPAFAEFLEEWLKTLRKYNGAVIFATQSVEDFLSSPIAEAIIE 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 711 NSASMYLLGQTEETVESVKRsgRLTLSEGGFHTLKTVHTIQGVYseiFIKSKSGMGVGRLIVGDFQKLLYSTDPVDVNAI 790
Cdd:COG3451 464 NSATKILLPQPKADIEDYAE--LLGLSERELELIRSAGRGKRDF---LIKQGNGSVVFRLDLSPEELALLSTKPEEVAIL 538
|
....*..
gi 446560040 791 DQFVKQG 797
Cdd:COG3451 539 DELRAEH 545
|
|
| PRK13721 |
PRK13721 |
conjugal transfer ATP-binding protein TraC; Provisional |
9-804 |
2.15e-74 |
|
conjugal transfer ATP-binding protein TraC; Provisional
Pssm-ID: 237480 [Multi-domain] Cd Length: 844 Bit Score: 259.27 E-value: 2.15e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 9 LEETLIPEHLRaagIIPVLAYDEDDHVFlMDDHSAGFGFMCEPLCGADEKVQERMNGFLNQEFPSKTTLQFVLFRSPDIN 88
Cdd:PRK13721 2 LGEMSFPQFSR---LLPYRDYDQESGLF-MNDTTMGFMLEAIPLNGANESIVEALDHMLRTKLPRGIPLCIHLMSSKLVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 89 QEMYRmmGLRD----GFRHELLTSVIKErinfLQHHTTERIFAKTNKGIYDNGLiQDLKLFVTCKVPIKNNnpTESELQQ 164
Cdd:PRK13721 78 DRIEY--GLREfswsGEQAERFNAITRA----YYMRAALTQFPLPEGMNLPLTL-RHYRVFISYCSPSKKK--SRADILE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 165 LAQLRTKVESSLQTVGLRPRTMTAVNYIRIMSTILNWGPDASWRHDSvDWEMDKPICEQIFDYGTDVEVSKNGIRLG--- 241
Cdd:PRK13721 149 MENLVKIIRASLQGASITTQTVDAQAFISIVREMINHRPDSLYPKRR-QLDPYSDLNYQCVEDSFDLKVRADYLTLGlre 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 242 ---DYHAKVMS--AKKLPDVFYfgdaLTYAGDlsggnssikeNYmvvTNVFFPE---------------AESTKNTLERK 301
Cdd:PRK13721 228 ngrNSTARILNfhLAKNPEIAF----LWQMAD----------NY---SNLLNPElsiscpfiltltlevEDQVKTQSEAN 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 302 RQFT-----VNQAYGpmlKFVPVLADKKESFDTLYESMKEGAKP-VKITYSVVLFAP-TKERVEAAAMAARNIWRESRFE 374
Cdd:PRK13721 291 LKYMdlekkSKTSYA---KWFPSVEKEAKEWGELRQRLGSNQSSlVSYFLNITAFCPdNNETALEVEQDILNSFRKNGFE 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 375 LMEDKFVALPMFLNCLPFCTDRDAVRDLfryKTM------TTEQAAVVLPVFGEWKGTGTYHAALISRNgQLMSLSLHD- 447
Cdd:PRK13721 368 LISPRFNHMRNFLTCLPFMAGEGLFKDL---KEAgvvqraESFNVANLMPLVADNPLTPAGLLAPTYRN-QLAFIDIFFr 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 448 --SNTNKNLVIAAESGSGKSFLTNELIFSYLSEGAQVWVIDAGKSYQKLSEMLNGDFVhfeEGTHVCLNPFELIQNYEDE 525
Cdd:PRK13721 444 gmNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGGFAVVFDMGDGYKSLCENMGGVYL---DGETLRFNPFANITDIDQS 520
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 526 EDAIVSLVCAMASAKGLLDEWQISALKQVLSRLWEEKGKEMKVDDIA-----ERCLEEENDQ-----RLKDIGQQLYAFT 595
Cdd:PRK13721 521 AERIRDQLSVMASPNGNLDEVHEGLLLQAVRASWLAKKNRARIDDVVdflknARDSEQYADSptirsRLDEMIVLLDQYT 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 596 SKGSYGKYF-SRKNNVSFQNQFTVLELDELQGRKHLRQVVLLQLIYQIQQEVFLGERNRKKVVIVDEAWDLL--KEGEVS 672
Cdd:PRK13721 601 ANGTYGEYFnSDEPSLRDDARMVVLELGGLEDRPSLLVAVMFSLIIYIENRMYRTPRNLKKLNVIDEGWRLLdfKNHKVG 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 673 VFMEHAYRKFRKYGGSVVIATQSINDL---YENAVGRAIAENSASMYLLGQTEETVESVKRSGRLTLSE------GGFHT 743
Cdd:PRK13721 681 EFIEKGYRTARRHTGAYITITQNIVDFdsdKASSAARAAWGNSSYKIILKQSAKEFAKYNQLYPDQFSPlerdmiGGFGA 760
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446560040 744 LKTVHtiqgvYSEIFIKSKSGMGVGRLIVGDFQKLLYSTDPVDVNAIDQFVKQGMSIPEAI 804
Cdd:PRK13721 761 AKDQW-----FSSFLLQVENHSSWHRLFVDPLSRAMYSSDGPDFEFVQQKRKEGLSIHEAV 816
|
|
| TraC_F_IV |
pfam11130 |
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a ... |
19-255 |
2.33e-73 |
|
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a cytoplasmic, peripheral membrane protein and is one of the proteins encoded by the F transfer region of the conjugative plasmid that is required for the assembly of F pilin into the mature F pilus structure. F pili are filamentous appendages that help establish the physical contact between donor and recipient cells involved in the conjugation process.
Pssm-ID: 431669 [Multi-domain] Cd Length: 232 Bit Score: 239.11 E-value: 2.33e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 19 RAAGIIPVLAYDEDDHVFLMDDHSAGFGFMCEPLCGADEKVQERMNGFLNQEFPSKTTLQFVLFRSPDINQEMYRMMGLR 98
Cdd:pfam11130 2 SFSDLLPYVAYDPETGLFLNEDGSVGFVFELSPLGGADESVRDTLESLLSDDLPDGTPVQFLLFASPDIGPYLDRLRDYR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 99 DGFRHELLTSVIKERINFLQHHTTERIFAktnkgiYDNGLIQDLKLFVTCKVPIKNNNPTesELQQLAQLRTKVESSLQT 178
Cdd:pfam11130 82 LGEQGGHLRAIARPRGLFLDSGVTGSLSA------DWRGQLRRFRLVLSRKVPGKADLPT--PIEALNELRDRLEASLRS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 179 VGLRPRTMTAVNYIRIMSTILNWGPDASWRHDSvDWEMDKPICEQIFDYGTDVEVSKNGIRLGD---YHAKVMSAKKLPD 255
Cdd:pfam11130 154 AGLAARRLDPDDLIAWLRRWLNPDPSASWDPPA-DYDPDKDIAEQILDSDPRLDVEAGRLYFDGephRAVRVLSLRRFPE 232
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
630-720 |
1.27e-08 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 54.53 E-value: 1.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 630 LRQVVLLQLIYQIQQEVFL--GERNRKKVVIVDEAWDLLKegevSVFMEHAYRKFRKYGGSVVIATQSINDLYENAV--- 704
Cdd:cd01127 53 LRALFFNQLFRALTELASLspGRLPRRVWFILDEFANLGR----IPNLPNLLATGRKRGISVVLILQSLAQLEAVYGkdg 128
|
90
....*....|....*.
gi 446560040 705 GRAIAENSASMYLLGQ 720
Cdd:cd01127 129 AQTILGNCNTKLYLGT 144
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| TraC-F-type |
TIGR02746 |
type-IV secretion system protein TraC; The protein family described here is common among the F, ... |
25-811 |
0e+00 |
|
type-IV secretion system protein TraC; The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.
Pssm-ID: 274279 [Multi-domain] Cd Length: 797 Bit Score: 611.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 25 PVLAYDEDDHVFlMDDHSAGFGFMCEPLCGADEKVQERMNGFLNQEFPSKTTLQFVLFRSPDINQEMYRMMGLRDGfRHE 104
Cdd:TIGR02746 3 PYRAYDEESGIF-MNRHSMGFGLELTPLSGADESLVESLSSLLRTDLPEGTDIQVLLWGSPQIGPFLDRNEEQFSQ-NGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 105 LLTSVIKERINFLQHhTTERIFAKTNkgiydNGLIQDLKLFVTCKVPIKNNNptESELQQLAQLRTKVESSLQTVGLRPR 184
Cdd:TIGR02746 81 ILEKLARNRVKYYLN-AAQKGFFKNS-----GVTLRDFRLFLSVSIPFKSPN--EDVIQELRSLRERIESTLRSAGFGCR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 185 TMTAVNYIRIMSTILNWGPDaSWRHDSVDWEMDKPICEQIFDYGTDVEVSKNGI--RLGDYHA------KVMSAKKLPD- 255
Cdd:TIGR02746 153 RVDAEDLLSLVREMLNPDPD-SIHPWPISYDPNQLLRDQIVDPDTDLEVHEGGLevDHEDNQGevktriRVFSIKRFPEe 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 256 --VFYFGDALtyaGDLSGGNSSIKENYMVVTNVFFPEAESTKNTLERKRQFTVNQAYGPMLKFVPVLADKKESFDTLYES 333
Cdd:TIGR02746 232 ftLWQTGNLI---GDLLNPSLQITCPFLLSFTVRVEDQVKKKAKATAKAKDLNKQAKSSMAKWVPSLEKKLKEIKYLREA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 334 -MKEGAKPVKITYSVVLFApTKERVEAAAMAARNIWRESRFELMEDKFVALPMFLNCLPFCTDRDAVRDL---FRYKTMT 409
Cdd:TIGR02746 309 iASGGDSLVSMYYNVLLFT-NPDNLRRDVEAAKSSFRKNGFDLAEDKRIQLQAFLAALPFNPTEGLFEDLkkaGRVRTLS 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 410 TEQAAVVLPVFGEWKGTGTYHAALISRNGQLMSLSLHDSN-TNKNLVIAAESGSGKSFLTNELIFSYLSEGAQVWVIDAG 488
Cdd:TIGR02746 388 SANAVNLLPLIADWKGTKGSGLLLPTRRGQLSAFDPFDSDsTNYNIAVVGGSGAGKSFFMQELIVDNLSRGGKVWVIDVG 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 489 KSYQKLSEMLNGDFVHFEEGTHVCLNPF--ELIQNYEDEEDAIVSLVCAMASAKGLLDEWQISALKQVLSRLWEEKGKEM 566
Cdd:TIGR02746 468 RSYKKLCEMLGGTYIEFSPESNICLNPFtgNNVTEIDDEIDQITALIALMASPEGGLSDEQRSTLEEAILAAWKEYGNEA 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 567 KVDDIAERCLE---EENDQRLKDIGQQLYAFTSKGSYGKYFSRKNNVSFQNQFTVLELDELQGRKHLRQVVLLQLIYQIQ 643
Cdd:TIGR02746 548 TITDVQDALQQledDENDPRIKDLGKMLNPYTSHGVYGRYFNGPNNLDFSNRFVVLELEELEDRPDLQAVVLFSLMVRIT 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 644 QEVFLGERNRKKVVIVDEAWDLL--KEGEVSVFMEHAYRKFRKYGGSVVIATQSINDLYENAVGRAIAENSASMYLLGQT 721
Cdd:TIGR02746 628 GEMYLTPRKRRKICIIDEAWSLLdgANPQAADFIETGYRRARKYGGAFITITQGIEDFYSSPEARAAYANSDWKIILRQS 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 722 EETVESVKRSGRLTLSEGGFHTLKTVHTIQGVYSEIFIKSKSGMGVGRLIVGDFQKLLYSTDPVDVNAIDQFVKQGMSIP 801
Cdd:TIGR02746 708 AESIAKLKAENPFTFSPFEKRLIKSLRTAKGAFSELLIRSGEGSSVHRLFVDPFSRVLFSTDGPEFEEVEELREQGLSLE 787
|
810
....*....|
gi 446560040 802 EAIKAVMRSR 811
Cdd:TIGR02746 788 EAIEQLAQKH 797
|
|
| VirB4 |
COG3451 |
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ... |
238-797 |
3.85e-118 |
|
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442674 [Multi-domain] Cd Length: 546 Bit Score: 368.12 E-value: 3.85e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 238 IRLGDYHAKVMSAKKLPDVFYFG--DALTyagdlsggnsSIKENYMVVTNVFFPEAESTKNTLERKRQFTVNQAYGPMLK 315
Cdd:COG3451 3 LEIGDRYGRVLSIKGYPSETSPGllDPLL----------QLPCEFIVTQSFTPLDKDEALKKLKRKRRRLESKRKSEQAL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 316 FVPVLADKKESFDTLYESMKEG-AKPVKITYSVVLFAPTKERVEAAAMAARNIWRESRFELMEDKFVALPMFLNCLPFCT 394
Cdd:COG3451 73 VDDDAESQAEDAEEALDELQSGgERLGEVHLTLTVFADDLEELEEAVREVESALQSAGFTLVRETLNQEEAFLSSLPGNF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 395 DRDavrdlFRYKTMTTEQAAVVLPVFGEWKGTGTYHAALISRNGQLMSLSLHDSNTNKNLVIAAESGSGKSFLTNELIFS 474
Cdd:COG3451 153 DYR-----LRRRLLTTSNLAALFPFHSFELGDPWGIYLLNTRSGTPVFFDFHDGLDNGNTLILGPSGSGKSFLLKLLLLQ 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 475 YLSEGAQVWVIDAGKSYQKLSEMLNGDFVHFEEGTHVCLNPFELIqNYEDEEDAIVSLVCAMASA-KGLLDEWQISALKQ 553
Cdd:COG3451 228 LLRYGARIVIFDPGGSYEILVRALGGTYIDLSPGSPTGLNPFDLE-DTEEKRDFLLELLELLLGReGEPLTPEERAAIDR 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 554 VLSRLWEEKGKEMK--VDDIAERCleeENDQRLKDIGQQLYAFTSKGSYGKYFSRKNNVSFQ-NQFTVLELDELQGRKHL 630
Cdd:COG3451 307 AVRALYRRADPEERttLSDLYELL---KEQPEAKDLAARLEPYTKGGSYGWLFDGPTNLDLSdARFVVFDLTELLDNPEL 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 631 RQVVLLQLIYQIQQEVFLGERNRKKVVIVDEAWDLLKEGEVSVFMEHAYRKFRKYGGSVVIATQSINDLYENAVGRAIAE 710
Cdd:COG3451 384 RPPVLLYLLHRIWNRLRKNNDGRPTLIVIDEAWLLLDNPAFAEFLEEWLKTLRKYNGAVIFATQSVEDFLSSPIAEAIIE 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 711 NSASMYLLGQTEETVESVKRsgRLTLSEGGFHTLKTVHTIQGVYseiFIKSKSGMGVGRLIVGDFQKLLYSTDPVDVNAI 790
Cdd:COG3451 464 NSATKILLPQPKADIEDYAE--LLGLSERELELIRSAGRGKRDF---LIKQGNGSVVFRLDLSPEELALLSTKPEEVAIL 538
|
....*..
gi 446560040 791 DQFVKQG 797
Cdd:COG3451 539 DELRAEH 545
|
|
| PRK13721 |
PRK13721 |
conjugal transfer ATP-binding protein TraC; Provisional |
9-804 |
2.15e-74 |
|
conjugal transfer ATP-binding protein TraC; Provisional
Pssm-ID: 237480 [Multi-domain] Cd Length: 844 Bit Score: 259.27 E-value: 2.15e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 9 LEETLIPEHLRaagIIPVLAYDEDDHVFlMDDHSAGFGFMCEPLCGADEKVQERMNGFLNQEFPSKTTLQFVLFRSPDIN 88
Cdd:PRK13721 2 LGEMSFPQFSR---LLPYRDYDQESGLF-MNDTTMGFMLEAIPLNGANESIVEALDHMLRTKLPRGIPLCIHLMSSKLVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 89 QEMYRmmGLRD----GFRHELLTSVIKErinfLQHHTTERIFAKTNKGIYDNGLiQDLKLFVTCKVPIKNNnpTESELQQ 164
Cdd:PRK13721 78 DRIEY--GLREfswsGEQAERFNAITRA----YYMRAALTQFPLPEGMNLPLTL-RHYRVFISYCSPSKKK--SRADILE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 165 LAQLRTKVESSLQTVGLRPRTMTAVNYIRIMSTILNWGPDASWRHDSvDWEMDKPICEQIFDYGTDVEVSKNGIRLG--- 241
Cdd:PRK13721 149 MENLVKIIRASLQGASITTQTVDAQAFISIVREMINHRPDSLYPKRR-QLDPYSDLNYQCVEDSFDLKVRADYLTLGlre 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 242 ---DYHAKVMS--AKKLPDVFYfgdaLTYAGDlsggnssikeNYmvvTNVFFPE---------------AESTKNTLERK 301
Cdd:PRK13721 228 ngrNSTARILNfhLAKNPEIAF----LWQMAD----------NY---SNLLNPElsiscpfiltltlevEDQVKTQSEAN 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 302 RQFT-----VNQAYGpmlKFVPVLADKKESFDTLYESMKEGAKP-VKITYSVVLFAP-TKERVEAAAMAARNIWRESRFE 374
Cdd:PRK13721 291 LKYMdlekkSKTSYA---KWFPSVEKEAKEWGELRQRLGSNQSSlVSYFLNITAFCPdNNETALEVEQDILNSFRKNGFE 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 375 LMEDKFVALPMFLNCLPFCTDRDAVRDLfryKTM------TTEQAAVVLPVFGEWKGTGTYHAALISRNgQLMSLSLHD- 447
Cdd:PRK13721 368 LISPRFNHMRNFLTCLPFMAGEGLFKDL---KEAgvvqraESFNVANLMPLVADNPLTPAGLLAPTYRN-QLAFIDIFFr 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 448 --SNTNKNLVIAAESGSGKSFLTNELIFSYLSEGAQVWVIDAGKSYQKLSEMLNGDFVhfeEGTHVCLNPFELIQNYEDE 525
Cdd:PRK13721 444 gmNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGGFAVVFDMGDGYKSLCENMGGVYL---DGETLRFNPFANITDIDQS 520
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 526 EDAIVSLVCAMASAKGLLDEWQISALKQVLSRLWEEKGKEMKVDDIA-----ERCLEEENDQ-----RLKDIGQQLYAFT 595
Cdd:PRK13721 521 AERIRDQLSVMASPNGNLDEVHEGLLLQAVRASWLAKKNRARIDDVVdflknARDSEQYADSptirsRLDEMIVLLDQYT 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 596 SKGSYGKYF-SRKNNVSFQNQFTVLELDELQGRKHLRQVVLLQLIYQIQQEVFLGERNRKKVVIVDEAWDLL--KEGEVS 672
Cdd:PRK13721 601 ANGTYGEYFnSDEPSLRDDARMVVLELGGLEDRPSLLVAVMFSLIIYIENRMYRTPRNLKKLNVIDEGWRLLdfKNHKVG 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 673 VFMEHAYRKFRKYGGSVVIATQSINDL---YENAVGRAIAENSASMYLLGQTEETVESVKRSGRLTLSE------GGFHT 743
Cdd:PRK13721 681 EFIEKGYRTARRHTGAYITITQNIVDFdsdKASSAARAAWGNSSYKIILKQSAKEFAKYNQLYPDQFSPlerdmiGGFGA 760
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446560040 744 LKTVHtiqgvYSEIFIKSKSGMGVGRLIVGDFQKLLYSTDPVDVNAIDQFVKQGMSIPEAI 804
Cdd:PRK13721 761 AKDQW-----FSSFLLQVENHSSWHRLFVDPLSRAMYSSDGPDFEFVQQKRKEGLSIHEAV 816
|
|
| TraC_F_IV |
pfam11130 |
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a ... |
19-255 |
2.33e-73 |
|
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a cytoplasmic, peripheral membrane protein and is one of the proteins encoded by the F transfer region of the conjugative plasmid that is required for the assembly of F pilin into the mature F pilus structure. F pili are filamentous appendages that help establish the physical contact between donor and recipient cells involved in the conjugation process.
Pssm-ID: 431669 [Multi-domain] Cd Length: 232 Bit Score: 239.11 E-value: 2.33e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 19 RAAGIIPVLAYDEDDHVFLMDDHSAGFGFMCEPLCGADEKVQERMNGFLNQEFPSKTTLQFVLFRSPDINQEMYRMMGLR 98
Cdd:pfam11130 2 SFSDLLPYVAYDPETGLFLNEDGSVGFVFELSPLGGADESVRDTLESLLSDDLPDGTPVQFLLFASPDIGPYLDRLRDYR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 99 DGFRHELLTSVIKERINFLQHHTTERIFAktnkgiYDNGLIQDLKLFVTCKVPIKNNNPTesELQQLAQLRTKVESSLQT 178
Cdd:pfam11130 82 LGEQGGHLRAIARPRGLFLDSGVTGSLSA------DWRGQLRRFRLVLSRKVPGKADLPT--PIEALNELRDRLEASLRS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 179 VGLRPRTMTAVNYIRIMSTILNWGPDASWRHDSvDWEMDKPICEQIFDYGTDVEVSKNGIRLGD---YHAKVMSAKKLPD 255
Cdd:pfam11130 154 AGLAARRLDPDDLIAWLRRWLNPDPSASWDPPA-DYDPDKDIAEQILDSDPRLDVEAGRLYFDGephRAVRVLSLRRFPE 232
|
|
| VirB4_CagE |
TIGR00929 |
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ... |
279-795 |
1.39e-29 |
|
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).
Pssm-ID: 273346 [Multi-domain] Cd Length: 785 Bit Score: 125.89 E-value: 1.39e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 279 NYMVVTNVFFPEAESTKNTLERKRQFTVNQAYGPMLkFVPVLADKKESFDTLYESMKEGAKpvkitySVVLFAPTKERVE 358
Cdd:TIGR00929 266 EFILTHSFSFLSKEAALSKLGRKRKRLISKGDRAKS-QIAELDEALDELTSGDFVMGEHHL------SLVVYAEDLEKLD 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 359 AAAMAARNIWRESRFELMEDKFVALPMFLNCLPfctdrDAVRDLFRYKTMTTEQAAVVLPVFGEWKGT------GTYHAA 432
Cdd:TIGR00929 339 AALREARSLLNACGIVAVIETLGLEAAFWSQLP-----GNFSWNPRKSLITSRNFASLIPFHNFNLGKlrgnpwGPALTL 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 433 LISRNGQLMSLSLH--DSNTNKNLVIAAESGSGKSFLTNELIFSYL-SEGAQVWVIDAGKSYQKLSEMLNGDFVHFEEGT 509
Cdd:TIGR00929 414 LKTQSGTPFYFNFHvrDAKVLGHTLIFGPTGSGKTTLLNFLLAQMQkYGGMTIFAFDKDRGMEIFIRAFGGAYLEIKDGE 493
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 510 HVCLNPFELIQNyEDEEDAIVSLVCAMASAKG--LLDEWQISALKQVLSRLWEEKgkeMKVDDIAErcLEEENDQRLKDI 587
Cdd:TIGR00929 494 PFGFNPFQLEDT-ERNRAFLKEWLAMLVTLDGstDISAEDRNALSSAIDTVYREG---PLIRSLSD--LLNFLPKDYIDL 567
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 588 GQQLYAFTSKGSYGKYF-SRKNNVSFqNQFTVLELDELQGRKHLRQVVLLQLIYQIQQEVflgeRNRKKVVIVDEAWDLL 666
Cdd:TIGR00929 568 ADRLEPWLKGGDYGWLFdNPTDDLDL-SKITGFDLTELLDNPKVATPVLMYLFHRINEAL----DGRPFLIIIDEAWQYL 642
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 667 KEGEVSVFMEHAYRKFRKYGGSVVIATQSINDLYENAVGRAIAENSASMYLLGQTEETVESVKRSGRLTLSEggFHTLKT 746
Cdd:TIGR00929 643 GNPVFAAKIRDWLKTLRKANGIVVLATQSINDALGSRIADSILEQCATKIFLPNPEADREDYAEGFKLTERE--FELLKS 720
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 446560040 747 VhtiqGVYSEIF-IKSKSGMGVGRLIVGDFQKLL--YSTDPVDVNAIDQFVK 795
Cdd:TIGR00929 721 T----PEESRKFlIKQGQSSVVAELNLGGMDNYLrvLSSDTENVEIIDALIK 768
|
|
| Bac_Flav_CT_G |
TIGR03783 |
Bacteroides conjugation system ATPase, TraG family; Members of this family include the ... |
450-720 |
8.02e-22 |
|
Bacteroides conjugation system ATPase, TraG family; Members of this family include the predicted ATPase, TraG, encoded by transfer region genes of conjugative transposons of Bacteroides, such as CTnDOT, found on the main chromosome. Members also include TraG homologs borne on plasmids in Bacteroides. The protein family is related to the conjugative transfer system ATPase VirB4. [Cellular processes, DNA transformation]
Pssm-ID: 163495 [Multi-domain] Cd Length: 829 Bit Score: 101.45 E-value: 8.02e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 450 TNKNLVIAAESGSGKSFLTNELIFSYLSEGAQVWVIDAGKSYQKLSEMLN-------GDFVHFEEGTHVCLNPFELIQNY 522
Cdd:TIGR03783 437 TNRNKFILGPSGSGKSFFTNHLVRQYYEQGTHILLVDTGNSYQGLCELIHrktrgedGIYFTYTEENPIAFNPFYTDDGV 516
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 523 EDEE--DAIVSLVCAM---------ASAKGLLDewqiSALKQVLSRLWEEKGKEMKVDDIAE------RCLEEENDQRLK 585
Cdd:TIGR03783 517 FDVEkrESIKTLILTLwkredepptRSEEVALS----NAVSAYIRLISEDRGIAPSFNTFYEyvkddyRAELEEKKVREK 592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 586 DIG-----QQLYAFTSKGSYGKYFSRKNNVSFQNQ-FTVLELDELQGRKHLRQVVLLqliyqIQQEVFLGERNR----KK 655
Cdd:TIGR03783 593 DFDidnflNVLEPYYKGGEYDFLLNSDKQLDLLHKrFIVFEIDAIKDNKILFPVVTI-----IIMEAFINKMRRlkgvRK 667
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446560040 656 VVIVDEAWDLLKEGEVSVFMEHAYRKFRKYGGSVVIATQSINDLYENA-VGRAIAENSASMYLLGQ 720
Cdd:TIGR03783 668 MILIEEAWKAIASANMAEYIKYLYKTVRKYFGEAIVVTQEVDDIISSPiVKESIINNSDCKILLDQ 733
|
|
| P-loop_TraG |
pfam19044 |
TraG P-loop domain; This entry represents the P-loop domain found in the TraG conjugation ... |
450-807 |
5.56e-20 |
|
TraG P-loop domain; This entry represents the P-loop domain found in the TraG conjugation protein.
Pssm-ID: 436917 [Multi-domain] Cd Length: 413 Bit Score: 93.35 E-value: 5.56e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 450 TNKNLVIAAESGSGKSFLTNELIFSYLSEGAQVWVIDAGKSYQKLSEMLNGDFVHFEEGTHVCLNPFeliqnYEDEEDai 529
Cdd:pfam19044 28 TNRNKFILGPSGSGKSFFTNHMVRSYYEQGAHVVLVDVGHSYKGLCELVGGYYFTYSEENPIRFNPF-----YIGDGD-- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 530 vslvcamasakgLLDEWQISALKQVLSRLWEEKG-------------------KEMKVDDIAERC-------LEEENDQR 583
Cdd:pfam19044 101 ------------VLDTEKKESIKTLLLALWKKDDesftrseyvalsnaltlyyEHLEKDPDIFPCfntfyefLRDEYLKV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 584 LK---------DIGQQLYA---FTSKGSYGkYF--SRKNNVSFQNQFTVLELDELQGRKHLRQVVLLqliyqIQQEVFLG 649
Cdd:pfam19044 169 LEedkvkekdfDIDNFLYVlrpYYKGGEFD-YLlnATENLDLLNERFIVFELDNIKDHPILFPVVTI-----IIMEVFIS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 650 eRNRK-----KVVIVDEAWD-LLKEGeVSVFMEHAYRKFRKYGGSVVIATQSINDLYENA-VGRAIAENSASMYLLGQTE 722
Cdd:pfam19044 243 -KMRKlkgirKMILIEEAWKaIAKEG-MAEYIKYLFKTVRKFFGEAIVVTQEVDDIISSPiVKDAIINNSDCKILLDQRK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 723 -----ETVESVkrsgrLTLSEggfhtlKTVHTIQGV---------YSEIFIkSKSG--MGVGRLIVGDFQKLLYSTDPVD 786
Cdd:pfam19044 321 yqnkfDQIQEL-----LGLTD------KEKALILSInkandpgrkYKEVFI-SLGGqlSKVYRTEVSLEEYLAYTTEETE 388
|
410 420
....*....|....*....|.
gi 446560040 787 VNAIDQFVKQGMSIPEAIKAV 807
Cdd:pfam19044 389 KLKVQEYAAKYGGIEKGIAAL 409
|
|
| DUF5934 |
pfam19357 |
Family of unknown function (DUF5934); This presumed domain found in type IV secretion system ... |
288-434 |
1.60e-13 |
|
Family of unknown function (DUF5934); This presumed domain found in type IV secretion system proteins is functionally uncharacterized. This domain family is found in proteobacteria, and is approximately 170 amino acids in length. The family is found in association with pfam11130. There are two conserved sequence motifs: GWDL and QGEY.
Pssm-ID: 437189 [Multi-domain] Cd Length: 172 Bit Score: 69.35 E-value: 1.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 288 FPEAESTKNTLERKRQFTVNQAYGPMLKFVPVLADKKESFDTLYESMKEGAKPVKITYSVVLFAPtKERVEAAAMAARNI 367
Cdd:pfam19357 23 YPDQEAASSKAGYKFMRTTSLADSKSARFLPQLKEQSAEWQHVQDELRQGRKLVRAFYSVTAFSP-KGKGDAHERTLKSV 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446560040 368 WRESRFELMEDKFVALPMFLNCLPFCT----DRDAVRdLFRYKTMTTEQAAVVLPVFGEWKGTGTYHAALI 434
Cdd:pfam19357 102 YKAAGWDLIDERYLQIMGLLAAMPLTLadglASDLER-MKRFRTMLTTTAANIAPLQGEYLGGPIPHLLLI 171
|
|
| HerA |
COG0433 |
Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase ... |
450-705 |
3.32e-13 |
|
Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains [Replication, recombination and repair];
Pssm-ID: 440202 [Multi-domain] Cd Length: 388 Bit Score: 72.33 E-value: 3.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 450 TNKNLVIAAESGSGKSFLTNELIFSYLSEGAQVWVIDAGKSYQKLSEM--LNGDFVHFE--EGTHVCLNPFELIQNYEDe 525
Cdd:COG0433 46 LNRHILILGATGSGKSNTLQVLLEELSRAGVPVLVFDPHGEYSGLAEPgaERADVGVFDpgAGRPLPINPWDLFATASE- 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 526 edaivslVCAMASAKGLLDEWQISALKQVLSRLWEEKGKEMKVDDIAERCLEEENDQR---------LKDIGQQLYAFTS 596
Cdd:COG0433 125 -------LGPLLLSRLDLNDTQRGVLREALRLADDKGLLLLDLKDLIALLEEGEELGEeygnvsaasAGALLRRLESLES 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 597 KGSY--GKYFSRKNNVSFQNQFTVLELDELQGRkhLRQVVLLQL---IYQIQQEVFLGERNRKKVVIV-DEAWDLLKEGE 670
Cdd:COG0433 198 ADGLfgEPGLDLEDLLRTDGRVTVIDLSGLPEE--LQSTFVLWLlreLFEARPEVGDADDRKLPLVLViDEAHLLAPAAP 275
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 446560040 671 vsvfmEHAYRKF-------RKYGGSVVIATQSINDLYENAVG 705
Cdd:COG0433 276 -----SALLEILeriaregRKFGVGLILATQRPSDIDEDVLS 312
|
|
| AAA_10 |
pfam12846 |
AAA-like domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
450-699 |
2.09e-10 |
|
AAA-like domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins, including VirB4 components of the Type IV secretory pathway and conjugal transfer protein TrbE. This entry includes the arcaheal Vir4/HerA homolog CedB, a membrane-bound protein that is highly induced upon UV treatment and essential for DNA transfer between Sulfolobus cells.
Pssm-ID: 315512 [Multi-domain] Cd Length: 362 Bit Score: 63.18 E-value: 2.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 450 TNKNLVIAAESGSGKSFlTNELIFSYLS-EGAQVWVIDAGKSYQKLSEML-----NGDFVHFEEGT--HVCLNPFELiqn 521
Cdd:pfam12846 20 NAPHSAIIGDLGGGKSV-LNKTLFYYIVlLGGKALYIDPKKERGQWKETLpeiahEINFVTLDSETenHGLLDPIVL--- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 522 YEDEEDAIvsLVCAMASAKGLLDEWQISALKQVLSRLWEE--KGKEMKVDDIAERcLEEENDQRLKDIGQQLYAFTsKGS 599
Cdd:pfam12846 96 LPREKEAE--STAIDILTNLTGDSSRDDEKFPALRKAVEAvtEGKQRGLLAVIEE-LRKEDPKAARNIADHLESVV-DGS 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 600 YGKY-FSR---KNNVSFQNQFTVLELDELQGRKH-----------LRQVVLLQLIYQIQQEVFLGERNRKKVVIVDEAWD 664
Cdd:pfam12846 172 LAHLlFSDgrvENAISFEKQVTILEVEDLDLPDKaerferltteqLLSVSMMFVIGTFAREFGSSDRKEFKVVFFDEAWI 251
|
250 260 270
....*....|....*....|....*....|....*
gi 446560040 665 LLKEGEVSVFMEHAYRKFRKYGGSVVIATQSINDL 699
Cdd:pfam12846 252 FTSSAQGKTLLKELVRIGRSYNAAVYLVTQSADDV 286
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
630-720 |
1.27e-08 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 54.53 E-value: 1.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 630 LRQVVLLQLIYQIQQEVFL--GERNRKKVVIVDEAWDLLKegevSVFMEHAYRKFRKYGGSVVIATQSINDLYENAV--- 704
Cdd:cd01127 53 LRALFFNQLFRALTELASLspGRLPRRVWFILDEFANLGR----IPNLPNLLATGRKRGISVVLILQSLAQLEAVYGkdg 128
|
90
....*....|....*.
gi 446560040 705 GRAIAENSASMYLLGQ 720
Cdd:cd01127 129 AQTILGNCNTKLYLGT 144
|
|
| VirD4 |
COG3505 |
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ... |
454-738 |
6.27e-07 |
|
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain] Cd Length: 402 Bit Score: 52.68 E-value: 6.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 454 LVIAAeSGSGKSFLTNELIFSYLSEGAQVWVIDA-GKSYQKLSEML--NGDFVH----FEEGTHVCLNPFELIQNYEDEE 526
Cdd:COG3505 3 LVIGP-TGSGKTVGLVIPNLTQLARGESVVVTDPkGDLAELTAGFRrrAGYDVYvfdpFDPERSHRWNPLDEIRDPADAQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 527 DAIVSLVCAMASAKGLLDEWQISA---LKQVLSRLWEEKGKEMkvDDIAERCLEEEND--QRLKDIGQQLYAFTsKGSYG 601
Cdd:COG3505 82 ELAEALIPALGGGGGGDPFWREAAralLAALILALAEEGRRTL--ADVYRLLSEPEEElrELLEALPESPHPPV-ADTLA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 602 KYFSRKNNV------SFQNQFTVLELDELQ---GRKH--LRQVV--------------------LLQLIY-QIQQEVF-- 647
Cdd:COG3505 159 AFLNAAEKTrssvlsTLASALELLSDPEVAaltSGSDfdLRDLIrekgtlylvlppddlstlapLLRLLLsQLIRALLrr 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 648 ---LGERNRKKVVIVDEA-----WDllkegevsvFMEHAYRKFRKYGGSVVIATQSINDL---YENAVGRAIAENSASM- 715
Cdd:COG3505 239 aerSGRLPRPVLLLLDEFanlgrLP---------SLETLLATGRGYGIRLVLILQSLAQLeaiYGEEGAETILGNCGTKi 309
|
330 340 350
....*....|....*....|....*....|....*...
gi 446560040 716 -----------YL---LGQTEETVESVKRS-GRLTLSE 738
Cdd:COG3505 310 flgvndpetaeYLselLGKRTVERRSESRSrGSRSRSR 347
|
|
| DUF87 |
pfam01935 |
Helicase HerA, central domain; This entry represents the central domain found in archaeal ... |
456-649 |
9.23e-06 |
|
Helicase HerA, central domain; This entry represents the central domain found in archaeal proteins such as DNA double-strand break repair helicase HerA (EC:3.6.4.12). HerA is a helicase which is able to utilize either 3' or 5' single-stranded DNA extensions for loading and subsequent DNA duplex unwinding. It forms a complex with NurA nuclease, this complex has the 5'-3' DNA end resection activity and is essential for cell viability in the crenarchaeon Sulfolobus islandicus. This domain includes the the central RecA-like catalytic core and a flanking four-helix bundle. The function of this prokaryotic domain is unknown. It contains several conserved aspartates and histidines that could be metal ligands.
Pssm-ID: 376671 [Multi-domain] Cd Length: 220 Bit Score: 47.75 E-value: 9.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 456 IAAESGSGKSFLTNELIFS-YLSEGAQVWVIDAGKSYQKLSEML-NGDFVHFEEGTHVCLNPFELiqNYEDEEDAIVSLV 533
Cdd:pfam01935 28 ILGSTGSGKSNTVAVLLEElLEKKGATVLIFDPHGEYGTLFRDLgAENVNVITPDPELKINPWLL--SPEDLADLLEELN 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 534 CAMASAkglldewQISALKQVLSRLWEEKGKEMKVDDIAERCLEEENDQRL---KDIGQQLYAFTSKGSygKYFSRKNNV 610
Cdd:pfam01935 106 LPNAEV-------QRSILEEALDQLKSEELGKLSIDELIEKILEELLTEAAelnKLSNDAIRRVLDKLE--RLLRSGGLI 176
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446560040 611 SFQNQFTVLELDELQgrkHLRQVVLLQL--IYQIQQEVFLG 649
Cdd:pfam01935 177 LTSTDIIKLILDILS---KGGKVNIIDLsgVDELLQDLVVS 214
|
|
| PRK13873 |
PRK13873 |
conjugal transfer ATPase TrbE; Provisional |
443-718 |
2.70e-04 |
|
conjugal transfer ATPase TrbE; Provisional
Pssm-ID: 237536 [Multi-domain] Cd Length: 811 Bit Score: 44.52 E-value: 2.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 443 LSLHDSNTNKNLVIAAeSGSGKSFLTNELIFSYLS-EGAQVWVIDAGKSYQKLSEMLNGDFVHF--EEGTHVCLNPFELI 519
Cdd:PRK13873 434 LSLHVGDVGHTLVVGP-TGAGKSVLLALMALQFRRyPGAQVFAFDFGGSIRAATLAMGGDWHDLggGADGSVALQPLARI 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 520 qnyeDEEDAivslvCAMASakglldEWqisalkqVLSRLWEEK---GKEMKVD-----------DIAERCLE------EE 579
Cdd:PRK13873 513 ----DDEAE-----RAWAA------EW-------IAGILAREGvavTPEVKEHiwsaltslasaPVEERTLTglsvllQS 570
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 580 NDqrLKdigQQLYAFTSKGSYGKYFSRKNNVSFQNQFTVLELDELQGRKHLRQVVLLQLIYQIQQEvFLGernRKKVVIV 659
Cdd:PRK13873 571 NA--LK---QALAPYCLGGPHGRLLDADAERLGSADVQAFEMEGLMGTKAAAPAVLSYLFHRIEDR-FDG---RPTLLIL 641
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446560040 660 DEAWDLLKEGevsVFMEHA---YRKFRKYGGSVVIATQSINDLYENAVGRAIAENSASMYLL 718
Cdd:PRK13873 642 DEAWLFLDDP---VFAAQLrewLKTLRKKNVSVIFATQSLADIDGSAIAPAIIESCPTRIFL 700
|
|
| TraG-D_C |
pfam12696 |
TraM recognition site of TraD and TraG; This family includes both TraG and TraD as well as ... |
675-743 |
5.58e-03 |
|
TraM recognition site of TraD and TraG; This family includes both TraG and TraD as well as VirD4 proteins. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. This domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore.
Pssm-ID: 432726 [Multi-domain] Cd Length: 125 Bit Score: 37.63 E-value: 5.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446560040 675 MEHAYRKFRKYGGSVVIATQSINDL---YENAVGRAIAENSAS-MYL--------------LGQTEETVESVKRSGRLTL 736
Cdd:pfam12696 18 LEKLISTGRSRGISLMLILQSIAQLeelYGKDGAETILGNCNTkVFLgggdeetakylsklLGKYTVVSTTTSSSSSGSG 97
|
....*..
gi 446560040 737 SEGGFHT 743
Cdd:pfam12696 98 GSGSSSS 104
|
|
|