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Conserved domains on  [gi|446563586|ref|WP_000640932|]
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iron-enterobactin ABC transporter permease [Escherichia coli]

Protein Classification

iron-enterobactin ABC transporter permease( domain architecture ID 10793391)

iron-enterobactin ABC transporter permease is part of the binding-protein-dependent transport system for ferric enterobactin

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-330 0e+00

iron-enterobactin ABC transporter permease;


:

Pssm-ID: 182463  Cd Length: 330  Bit Score: 526.59  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   1 MIYVSRRLIITCLLLLIACVMAGVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF 80
Cdd:PRK10440   1 MIYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA 160
Cdd:PRK10440  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML 240
Cdd:PRK10440 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLML 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 241 VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320
Cdd:PRK10440 241 VAVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320

                        330
                 ....*....|
gi 446563586 321 VLLIQESRKK 330
Cdd:PRK10440 321 VLLIQESRKK 330
 
Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-330 0e+00

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 526.59  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   1 MIYVSRRLIITCLLLLIACVMAGVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF 80
Cdd:PRK10440   1 MIYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA 160
Cdd:PRK10440  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML 240
Cdd:PRK10440 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLML 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 241 VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320
Cdd:PRK10440 241 VAVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320

                        330
                 ....*....|
gi 446563586 321 VLLIQESRKK 330
Cdd:PRK10440 321 VLLIQESRKK 330
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 4-329 7.67e-112

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 328.23  E-value: 7.67e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   4 VSRRLIITCLLLLIACVMAGVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSL 83
Cdd:COG4779   18 LRRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  84 MRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNT 163
Cdd:COG4779   98 TRNPLASPDIIGITAGASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNS 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 164 WLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAV 243
Cdd:COG4779  178 YLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAV 257

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 244 VLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLL 323
Cdd:COG4779  258 ALAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLL 337


                 ....*.
gi 446563586 324 IQESRK 329
Cdd:COG4779  338 IRENRR 343
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 22-325 2.36e-64

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 205.84  E-value: 2.36e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   22 AGVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAW 101
Cdd:pfam01032   5 LILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  102 SGVLVAMVLFG-QDLTAIALAAMAGGIVTSLLVWLLA-WRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGL 179
Cdd:pfam01032  85 LGAVLAILLGGsLSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQSILF 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  180 WNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFI 259
Cdd:pfam01032 165 WLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFV 244

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446563586  260 ALVAPHIARRISGTA-RWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQ 325
Cdd:pfam01032 245 GLIVPHIARLLVGANhRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 63-323 3.66e-42

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 146.93  E-value: 3.66e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  63 VLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQ-DLTAIALAAMAGGIVTSLLVWLLAWRNG 141
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGlSNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 142 IDTFRLIIIGIGVRAMLVAFNTWLLLKASlETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGD 221
Cdd:cd06550   81 LSPSKLILIGIVLSAFFSAGVILISLLSD-DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 222 DTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFM 301
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|..
gi 446563586 302 PYQLPVGVVTVSLGGIYLIVLL 323
Cdd:cd06550  240 PSELPVGPVTALLGAPYFLYLL 261
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 54-328 2.91e-22

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 95.31  E-value: 2.91e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   54 VVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQdlTAIALAAMAGGIVTSLLV 133
Cdd:TIGR03869  48 IVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVA--VLLPVAAFAGALLALAAT 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  134 WLLAWRNGIDT-FRLIIIGIGVRAMLVAFNTWLLL-KASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLV 211
Cdd:TIGR03869 126 LGLARTLGTLTpTRTILAGLAVSQLCAAVTSFVIFwSATGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASG 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  212 RRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTA-RWGLTQAALCGALLLL 290
Cdd:TIGR03869 206 RVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRhRLLLPVSALAGAVFLV 285

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 446563586  291 AADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 328
Cdd:TIGR03869 286 WADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
 
Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-330 0e+00

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 526.59  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   1 MIYVSRRLIITCLLLLIACVMAGVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF 80
Cdd:PRK10440   1 MIYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA 160
Cdd:PRK10440  81 QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML 240
Cdd:PRK10440 161 FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLML 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 241 VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320
Cdd:PRK10440 241 VAVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI 320

                        330
                 ....*....|
gi 446563586 321 VLLIQESRKK 330
Cdd:PRK10440 321 VLLIQESRKK 330
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 4-329 7.67e-112

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 328.23  E-value: 7.67e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   4 VSRRLIITCLLLLIACVMAGVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSL 83
Cdd:COG4779   18 LRRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  84 MRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNT 163
Cdd:COG4779   98 TRNPLASPDIIGITAGASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNS 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 164 WLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAV 243
Cdd:COG4779  178 YLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAV 257

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 244 VLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLL 323
Cdd:COG4779  258 ALAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLL 337


                 ....*.
gi 446563586 324 IQESRK 329
Cdd:COG4779  338 IRENRR 343
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 22-325 2.36e-64

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 205.84  E-value: 2.36e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   22 AGVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAW 101
Cdd:pfam01032   5 LILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  102 SGVLVAMVLFG-QDLTAIALAAMAGGIVTSLLVWLLA-WRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGL 179
Cdd:pfam01032  85 LGAVLAILLGGsLSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQSILF 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  180 WNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFI 259
Cdd:pfam01032 165 WLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFV 244

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446563586  260 ALVAPHIARRISGTA-RWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQ 325
Cdd:pfam01032 245 GLIVPHIARLLVGANhRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 26-324 5.09e-60

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 194.52  E-value: 5.09e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  26 GLRSGAVTLETSQVFAALMGDAPRSMT-MVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGV 104
Cdd:COG0609    1 SLSLGAVPISLSDVLRALLGPDGDPTAdLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 105 LVAMVLFGQ-DLTAIALAAMAGGIVTSLLVWLLAWRN-GIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLWNA 182
Cdd:COG0609   81 VLAIVLGGGlSALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWLM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 183 GSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALV 262
Cdd:COG0609  161 GSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLV 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446563586 263 APHIARRISGT-ARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLI 324
Cdd:COG0609  241 VPHIARLLVGPdHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLR 303
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
55-329 1.96e-45

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 163.86  E-value: 1.96e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  55 VTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQD-LTAIALAAMAGGIVTSLLV 133
Cdd:PRK10577 393 LLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAgFGWLLAAALLGALAALALI 472

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 134 WLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETAlTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRR 213
Cdd:PRK10577 473 LLLARRGGFAPERLLLTGIALSALFTALIQLLLASGDPRAA-QLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRW 551

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 214 MRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISG-TARWGLTQAALCGALLLLAA 292
Cdd:PRK10577 552 LDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGrRARPQLVLAALLGALLMVLA 631

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 446563586 293 DLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRK 329
Cdd:PRK10577 632 DWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSRRR 668
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 63-323 3.66e-42

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 146.93  E-value: 3.66e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  63 VLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQ-DLTAIALAAMAGGIVTSLLVWLLAWRNG 141
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGlSNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 142 IDTFRLIIIGIGVRAMLVAFNTWLLLKASlETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGD 221
Cdd:cd06550   81 LSPSKLILIGIVLSAFFSAGVILISLLSD-DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 222 DTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFM 301
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                        250       260
                 ....*....|....*....|..
gi 446563586 302 PYQLPVGVVTVSLGGIYLIVLL 323
Cdd:cd06550  240 PSELPVGPVTALLGAPYFLYLL 261
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
5-268 1.05e-41

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 153.46  E-value: 1.05e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   5 SRRLIITCLLLLIACVMAGVWGLRSGAVTLETSQVFAALMGDAPRSM-TMVVTEWRLPRVLMALLIGAALGVSGAIFQSL 83
Cdd:PRK10577   7 RRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLeQLLLHYSRLPRLAIALLVGAALGLAGALLQQV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  84 MRNPLGSPDVMGFNTGAWSGVLVAMvLFGQDLTAIA--LAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAF 161
Cdd:PRK10577  87 LRNPLASPTTLGVAAGAQLALVLAT-LFAPALLALAsqLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYLGAL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 162 NTWLLLkASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLV 241
Cdd:PRK10577 166 TTLLLL-FNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALAL 244

                        250       260
                 ....*....|....*....|....*..
gi 446563586 242 AVVLTAAATALAGPISFIALVAPHIAR 268
Cdd:PRK10577 245 AVLLSAAVVSAVGPIGFIGLAAPNLAR 271
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
27-325 2.62e-38

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 138.26  E-value: 2.62e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  27 LRSGAVTLETSQVFAALMGDapRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLV 106
Cdd:PRK09777  21 LRMGVIPLPWRALLTDWQAG--DEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHAASLASVG 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 107 AMVLF-GQDLTAIALAAMAGGIVTSLLVWLLAWRNgiDTFRLIIIGIGVRAMLVAFNTWLLLKASLETAlTAGLWNAGSL 185
Cdd:PRK09777  99 ALLLFpSLPVMWLPLLAFIGGMAGLILLKMLAGTH--QPMKLALTGVALSALWASLTDYLMLSRPQDIN-NALLWLTGSL 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 186 NGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPH 265
Cdd:PRK09777 176 WGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGPISFIGLVVPH 255

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446563586 266 IARRI-SGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQ 325
Cdd:PRK09777 256 LMRSLvGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLLVR 316
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
41-315 3.51e-29

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 114.02  E-value: 3.51e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  41 AALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLT--AI 118
Cdd:PRK11228  33 ALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSALSPTPFAgySL 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 119 ALAAMAGGIVTSLLVWLL--AWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASlETALTAGLWNAGSLNGLTWAKTSPS 196
Cdd:PRK11228 113 AFIAACGGGLSWLLVMTAggGWRHTHDRNRLILAGIALSALCMALTRITLLLAE-DHAYGIFYWLAGGVSHARWQEVWQL 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 197 APIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISG-TAR 275
Cdd:PRK11228 192 LPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGyDQR 271

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 446563586 276 WGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLG 315
Cdd:PRK11228 272 NVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIG 311
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
20-328 5.18e-29

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 114.03  E-value: 5.18e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  20 VMAGVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTG 99
Cdd:PRK10441  21 IIATALSLLIGAKSLPASVVLEALSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAG 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 100 AWSGVLVAMVLFG-QDLTAIALAAMAGGIVTSLLVWLLAWRNG--IDTFRLIIIGIGVRAMLVAFNTWL-LLKASLETAL 175
Cdd:PRK10441 101 ASFAIVLGAALFGySSAQEQLAMAFAGALVASLIVAFTGSQGGgqLSPVRLTLAGVALAAVLEGLTSGIaLLNPDVYDQL 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 176 TagLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGP 255
Cdd:PRK10441 181 R--FWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGP 258

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446563586 256 ISFIALVAPHIARRISGT-ARWGLTqAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 328
Cdd:PRK10441 259 IAFIGLMMPHMARWLVGAdHRWSLP-VTLLATPALLLFADIIGRLLVPGELRVSVVSAFIGAPVLIFLVRRKTR 331
btuC PRK09535
cobalamin ABC transporter permease BtuC;
31-323 7.10e-29

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 114.08  E-value: 7.10e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  31 AVTLETSQVFAAlmgDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVL 110
Cdd:PRK09535  70 APDLEYASPFSF---AVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVL 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 111 FGQDLTAIALAAMAGGIVTSLLVWLLAWRNG-IDTFRLIIIGIGVRAMLVAFNTWLLLKA--SLETALtagLWNAGSLNG 187
Cdd:PRK09535 147 PLAVPFGLQAAAFAGALVAAFGVYAIATENGrTPVATLLLAGVAVQTFLGAVISYLLLHSgeSLRRAV---YWLMGHLHG 223

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 188 LTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIA 267
Cdd:PRK09535 224 STWSDVEVALPVVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVM 303

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446563586 268 RRISGTARWGLTQAALCGALLLLAADLCAQQLfMPYQLPVGVVTVSLGGIYLIVLL 323
Cdd:PRK09535 304 RLLVGPDHRILLPTSALAGASFLVATDTVARS-GPAEVPVGIVTAALGAPFFLYLL 358
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 53-324 6.05e-28

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 110.71  E-value: 6.05e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  53 MVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLT--AIALAAMAGGIVTS 130
Cdd:COG4139   49 LFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLLGGGLLPpwLLSLAAIAGALLVT 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 131 LLVWLLAwRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIaAALL 210
Cdd:COG4139  129 LLLLAFA-RRRLSNARLLLIGVALGIICSAIMTWAVYFSSSLDLRQLMYWMMGSFGGVDWRQLWLLLALLPVLLW-LCLQ 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 211 VRRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGT-ARWGLTQAALCGALLL 289
Cdd:COG4139  207 GKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTdHRFLLPACALAGAALL 286

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 446563586 290 LAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLI 324
Cdd:COG4139  287 LLADIIARLALSSAELPIGVVTATLGAPVFIWLLL 321
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 54-328 7.75e-23

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 96.95  E-value: 7.75e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  54 VVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLT--AIALAAMAGGIVTSL 131
Cdd:PRK03784  53 FVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPpwALSLCAIAGALLITL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 132 LVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILmLIAAALLV 211
Cdd:PRK03784 133 ILLRFARRHRLSTSRLLLAGVALGIICSALMTWAVYFSTSLDLRQLMYWMMGGFGGVDWRQSWLMLALLPV-LIWLCCQG 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 212 RRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGT-ARWGLTQAALCGALLLL 290
Cdd:PRK03784 212 RPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTdHRVLLPGCALAGASLLL 291

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 446563586 291 AADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 328
Cdd:PRK03784 292 LADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHR 329
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 54-328 2.91e-22

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 95.31  E-value: 2.91e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586   54 VVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQdlTAIALAAMAGGIVTSLLV 133
Cdd:TIGR03869  48 IVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVA--VLLPVAAFAGALLALAAT 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  134 WLLAWRNGIDT-FRLIIIGIGVRAMLVAFNTWLLL-KASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLV 211
Cdd:TIGR03869 126 LGLARTLGTLTpTRTILAGLAVSQLCAAVTSFVIFwSATGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASG 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  212 RRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTA-RWGLTQAALCGALLLL 290
Cdd:TIGR03869 206 RVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRhRLLLPVSALAGAVFLV 285

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 446563586  291 AADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 328
Cdd:TIGR03869 286 WADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
CeuC COG4605
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 59-329 1.17e-07

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443655  Cd Length: 317  Bit Score: 52.42  E-value: 1.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586  59 RLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNT--GAWSGVLVAM-------VLFGQDLTAIALAAMAgGIVT 129
Cdd:COG4605   39 RGTKLAAMLLVAIAIAVSTVLFQTITNNRILTPSIMGFDSlyVLIQTLLVFFlgsaglaALNPLLNFLLEVALMV-GFSL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 130 SLLVWLLAwRNGIDTFRLIIIGIGVRAMLVAFNTWLLLK------ASLETALTAGLWNAGSlnGLTWaktsPSAPIIILM 203
Cdd:COG4605  118 LLYRWLFR-GGRRNLHLLLLVGVVLGTLFRSLSSFLQRLidpnefDVLQDRLFASFNNVNT--DLLL----IAAVIVLLA 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446563586 204 LIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTAR--WGLTQA 281
Cdd:COG4605  191 LLLLWRLRRRLDVLALGRDQAINLGVDYRRVVRRLLILVAVLVAVSTALVGPITFLGLLVANLAYQLFGTYRhrYLLPAA 270

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 446563586 282 ALCGALLLLAADLCAQQLFMpYQLPVGVVTVSLGGIYLIVLLIQESRK 329
Cdd:COG4605  271 ALIGVIALVGGQFVVEHVFN-FSTTLSVIIEFVGGIYFLYLLLRKRRL 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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