|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10436 |
PRK10436 |
hypothetical protein; Provisional |
1-459 |
0e+00 |
|
hypothetical protein; Provisional
Pssm-ID: 236694 Cd Length: 462 Bit Score: 838.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 1 MKDAQLNTLCQRHQAVLINSASNSITVAVVDAPSHALLDALHFATQKQIDIVCWTRQQMENHRHKPDQAPSANAAKGGET 80
Cdd:PRK10436 4 MNIDQLHALCQRYQAVLLDSDEETLHVAVVDAPSHELLDALRFATGKRIEIECWPRAQMEQHLQRTQQTLPVADQEKDTP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 81 AAQLLNQTLRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIAEHRLPQDGQFTVDL 160
Cdd:PRK10436 84 VAQLINQTLQSALQKRASDIHFEPAQNHYRIRLRIDGVLHPLPDPSPELGAALTARLKVLGNLDIAERRLPQDGQFTVEL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 161 AGDSISFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQGLVLVTGPTGSGKTVTLYSALQTRN 240
Cdd:PRK10436 164 AGNAYSFRIATLPCRGGEKVVLRLLQQVQQALDLETLGMTPAQLAQFRQALQQPQGLILVTGPTGSGKTVTLYSALQTLN 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 241 TPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNS 320
Cdd:PRK10436 244 TAQINICSVEDPVEIPLAGINQTQIHPKAGLTFQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAAQTGHLVLSTLHTNS 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 321 TSETLIRLQQMGVARWMISSALTLVVAQRLVRKLCPHCKQRLSDPVVLSPNLWPSALPRWQANGCQHCYHGFYGRTALFE 400
Cdd:PRK10436 324 TSETLVRLQQMGIARWMLASALKLVIAQRLVRKLCPHCRQQASEPIHLPPNIWPGPLPHWQAVGCEHCYHGYYGRTALFE 403
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 446573249 401 VLTVTPALRQLIASGASAQALEAHLQQTGTGTLFENGCRAVEQGMTSFEEILRVLGMPH 459
Cdd:PRK10436 404 VLPITPVLQQAIASNASPEELETHARQQGMTTLFENGLLAVEQGLTTLEELYRVLGMPH 462
|
|
| PulE |
COG2804 |
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ... |
9-457 |
0e+00 |
|
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 442055 [Multi-domain] Cd Length: 561 Bit Score: 621.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 9 LCQRHQAVLINSASNSITVAVVDAPSHALLDALHFATQKQIDIVCWTRQQMENHRHK--------------------PDQ 68
Cdd:COG2804 85 LARRHRVLPLRLEGGTLTVAMADPLDLEALDELRRLTGRPVEPVVATESDIERALDRlygsessieelleelaedltSEE 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 69 APSANAAKGGETAA--QLLNQTLRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIA 146
Cdd:COG2804 165 EDLEDLLEEADDAPvvRLVNAILEDAIKEGASDIHIEPYEKRLRVRFRIDGVLREVLRLPKSLAPALVSRIKIMANLDIA 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 147 EHRLPQDGQFTVDLAGDSISFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQGLVLVTGPTGS 226
Cdd:COG2804 245 ERRLPQDGRIKLRLGGREIDLRVSTLPTVYGEKVVLRILDKSAALLDLEQLGFSPDQLERLRRLIRRPHGIILVTGPTGS 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 227 GKTVTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAA 306
Cdd:COG2804 325 GKTTTLYAALNELNTPERNIITVEDPVEYQLPGINQVQVNPKIGLTFASALRSILRQDPDVIMVGEIRDLETAEIAVQAA 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 307 QTGHLVLSTLHTNSTSETLIRLQQMGVARWMISSALTLVVAQRLVRKLCPHCKQrlsdPVVLSPNLW---------PSAL 377
Cdd:COG2804 405 LTGHLVLSTLHTNDAPSAITRLLDMGVEPFLLASSLLGVLAQRLVRRLCPHCKE----PYEPDPEELerlglppeeLAPL 480
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 378 PRWQANGCQHCYH-GFYGRTALFEVLTVTPALRQLIASGASAQALEAHLQQTGTGTLFENGCRAVEQGMTSFEEILRVLG 456
Cdd:COG2804 481 TFYRGVGCEHCNGtGYKGRTGIYELLVIDDELRELIAEGASAAELREAARKEGMRTLREDGLEKVLQGITTLEEVLRVTG 560
|
.
gi 446573249 457 M 457
Cdd:COG2804 561 E 561
|
|
| type_IV_pilB |
TIGR02538 |
type IV-A pilus assembly ATPase PilB; This model describes a protein of type IV pilus ... |
9-454 |
6.15e-162 |
|
type IV-A pilus assembly ATPase PilB; This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274186 [Multi-domain] Cd Length: 564 Bit Score: 469.11 E-value: 6.15e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 9 LCQRHQAVLINSASNSITVAVVDAPSHALLDALHFATQKQIDIVCWTRQQMENHRHKP-DQAPSANAAKGGETAAQL--- 84
Cdd:TIGR02538 78 LIQKHQALPLFKRGNTLFVAVSDPTNISALDDIRFATGLNVEVVIVEEDKLSALIEKYyGGSDSLAKELGDEDIGDLeel 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 85 ---------------------------LNQTLRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARL 137
Cdd:TIGR02538 158 dvdaiddegpddieqdavdddapivkfVNKILLDAIRKGASDIHFEPYEKSYRVRFRIDGILHEVAQPPLALANRIAARI 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 138 KVLGNLDIAEHRLPQDGQFTVDLA-GDSISFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQG 216
Cdd:TIGR02538 238 KVMSRLDIAEKRIPQDGRIKLKLSkSKAIDFRVSTLPTLFGEKVVLRILDSSAAQLDIDKLGFEPDQKALFLEAIHKPQG 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 217 LVLVTGPTGSGKTVTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDG 296
Cdd:TIGR02538 318 MVLVTGPTGSGKTVSLYTALNILNTEEVNISTAEDPVEINLPGINQVNVNPKIGLTFAAALRSFLRQDPDIIMVGEIRDL 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 297 DTAEIAIKAAQTGHLVLSTLHTNSTSETLIRLQQMGVARWMISSALTLVVAQRLVRKLCPHCKQ--RLSDPVVLSPNLWP 374
Cdd:TIGR02538 398 ETAEIAIKAAQTGHLVLSTLHTNDAPETLARLVNMGIAPFNIASSVNLIMAQRLARRLCSHCKApeEVPAEALLELGFTQ 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 375 SALPRWQ---ANGCQHC-YHGFYGRTALFEVLTVTPALRQLIASGASAQALEAHLQQTGTGTLFENGCRAVEQGMTSFEE 450
Cdd:TIGR02538 478 EDLADLKlygPVGCDECsNTGYKGRVGIYEVMPMSEEIAELILKGGNALQIAELAQKEGMRTLRRSGLLKVKQGVTSLEE 557
|
....
gi 446573249 451 ILRV 454
Cdd:TIGR02538 558 VLRV 561
|
|
| T2SSE |
pfam00437 |
Type II/IV secretion system protein; This family contains components of both the Type II ... |
86-354 |
4.04e-126 |
|
Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.
Pssm-ID: 425681 [Multi-domain] Cd Length: 269 Bit Score: 366.99 E-value: 4.04e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 86 NQTLRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIAEHRLPQDGQFTVDLAGDSI 165
Cdd:pfam00437 1 NLIPLEALDEGASDIHVEPPERIVWIRFRVDGVLREIPFPDADALARLISRIKVMARLDISERRPPQDGRLPLRIGGKGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 166 SFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQGLVLVTGPTGSGKTVTLYSALQTRNTPGIN 245
Cdd:pfam00437 81 RVRVSTLPTAGGEKLVIRLLDPSNVALSLDELGMTGAQDEALLEFLRQPRGNILVTGPTGSGKTTTLYAALGELNTRDEN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 246 LCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETL 325
Cdd:pfam00437 161 IVTVEDPVEIQLEGINQVQLNARAGVTFADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHTNSAAGAL 240
|
250 260
....*....|....*....|....*....
gi 446573249 326 IRLQQMGVARWMISSALTLVVAQRLVRKL 354
Cdd:pfam00437 241 TRLQDMGVPPFELASSLLLVIAQRLVRKL 269
|
|
| ATPase_ComGA |
NF041000 |
competence type IV pilus ATPase ComGA; |
89-351 |
2.18e-94 |
|
competence type IV pilus ATPase ComGA;
Pssm-ID: 468930 [Multi-domain] Cd Length: 265 Bit Score: 285.88 E-value: 2.18e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 89 LRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIAEHRLPQDGQFTVDLAGDSISFR 168
Cdd:NF041000 4 IEEAIELRASDIHFLPREDGYQIKFRIGGGLIPYRELSLEEGQRLISYFKFLAGMDIGEKRRPQSGAFTYELNEQQISLR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 169 IATLPCKEG-EKVVLRLLHQVEQTLDLDtlgMYGAQLTAFRQALQQPQGLVLVTGPTGSGKTVTLYSALQtRNTPGINLC 247
Cdd:NF041000 84 LSTVGDFLGrESLVIRLLYQLEQIKPQL---FFPEQFQLLKQLLQRRSGLILFSGPTGSGKTTTMYSLAR-KLALNKQVI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 248 SVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIR 327
Cdd:NF041000 160 TIEDPVEIKEPNFLQLQVNEKAGMTYDTLLKAALRHRPDILIIGEIRDAETAKAAIRAALTGHLVLSTVHAKSAAGVIYR 239
|
250 260
....*....|....*....|....
gi 446573249 328 LQQMGVARWMISSALTLVVAQRLV 351
Cdd:NF041000 240 LLELGISKEELEQTLIGISYQRLI 263
|
|
| PulE-GspE-like |
cd01129 |
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ... |
207-353 |
5.33e-82 |
|
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.
Pssm-ID: 410873 [Multi-domain] Cd Length: 159 Bit Score: 250.10 E-value: 5.33e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 207 FRQALQQPQGLVLVTGPTGSGKTVTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPD 286
Cdd:cd01129 3 LRRLIKRPHGLILVTGPTGSGKTTTLYAMLRELNGPERNIITIEDPVEYQIPGINQSQVNEKIGLTFADALRAILRQDPD 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446573249 287 IIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIRLQQMGVARWMISSALTLVVAQRLVRK 353
Cdd:cd01129 83 IIMVGEIRDAETAEIAIRAALTGHLVLSTLHTNDALGAITRLLDMGIEPFLLASALRGVIAQRLVGR 149
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
214-293 |
2.07e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.51 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 214 PQGLVLVTGPTGSGKTVTLYSALQ--TRNTPGINLCSVEDPIEIPLDGINQTQIHPRA-----GLTFQNVLRALLRQDPD 286
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARelGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKasgsgELRLRLALALARKLKPD 80
|
....*..
gi 446573249 287 IIMVGEI 293
Cdd:smart00382 81 VLILDEI 87
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10436 |
PRK10436 |
hypothetical protein; Provisional |
1-459 |
0e+00 |
|
hypothetical protein; Provisional
Pssm-ID: 236694 Cd Length: 462 Bit Score: 838.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 1 MKDAQLNTLCQRHQAVLINSASNSITVAVVDAPSHALLDALHFATQKQIDIVCWTRQQMENHRHKPDQAPSANAAKGGET 80
Cdd:PRK10436 4 MNIDQLHALCQRYQAVLLDSDEETLHVAVVDAPSHELLDALRFATGKRIEIECWPRAQMEQHLQRTQQTLPVADQEKDTP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 81 AAQLLNQTLRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIAEHRLPQDGQFTVDL 160
Cdd:PRK10436 84 VAQLINQTLQSALQKRASDIHFEPAQNHYRIRLRIDGVLHPLPDPSPELGAALTARLKVLGNLDIAERRLPQDGQFTVEL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 161 AGDSISFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQGLVLVTGPTGSGKTVTLYSALQTRN 240
Cdd:PRK10436 164 AGNAYSFRIATLPCRGGEKVVLRLLQQVQQALDLETLGMTPAQLAQFRQALQQPQGLILVTGPTGSGKTVTLYSALQTLN 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 241 TPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNS 320
Cdd:PRK10436 244 TAQINICSVEDPVEIPLAGINQTQIHPKAGLTFQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAAQTGHLVLSTLHTNS 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 321 TSETLIRLQQMGVARWMISSALTLVVAQRLVRKLCPHCKQRLSDPVVLSPNLWPSALPRWQANGCQHCYHGFYGRTALFE 400
Cdd:PRK10436 324 TSETLVRLQQMGIARWMLASALKLVIAQRLVRKLCPHCRQQASEPIHLPPNIWPGPLPHWQAVGCEHCYHGYYGRTALFE 403
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 446573249 401 VLTVTPALRQLIASGASAQALEAHLQQTGTGTLFENGCRAVEQGMTSFEEILRVLGMPH 459
Cdd:PRK10436 404 VLPITPVLQQAIASNASPEELETHARQQGMTTLFENGLLAVEQGLTTLEELYRVLGMPH 462
|
|
| PulE |
COG2804 |
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ... |
9-457 |
0e+00 |
|
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 442055 [Multi-domain] Cd Length: 561 Bit Score: 621.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 9 LCQRHQAVLINSASNSITVAVVDAPSHALLDALHFATQKQIDIVCWTRQQMENHRHK--------------------PDQ 68
Cdd:COG2804 85 LARRHRVLPLRLEGGTLTVAMADPLDLEALDELRRLTGRPVEPVVATESDIERALDRlygsessieelleelaedltSEE 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 69 APSANAAKGGETAA--QLLNQTLRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIA 146
Cdd:COG2804 165 EDLEDLLEEADDAPvvRLVNAILEDAIKEGASDIHIEPYEKRLRVRFRIDGVLREVLRLPKSLAPALVSRIKIMANLDIA 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 147 EHRLPQDGQFTVDLAGDSISFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQGLVLVTGPTGS 226
Cdd:COG2804 245 ERRLPQDGRIKLRLGGREIDLRVSTLPTVYGEKVVLRILDKSAALLDLEQLGFSPDQLERLRRLIRRPHGIILVTGPTGS 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 227 GKTVTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAA 306
Cdd:COG2804 325 GKTTTLYAALNELNTPERNIITVEDPVEYQLPGINQVQVNPKIGLTFASALRSILRQDPDVIMVGEIRDLETAEIAVQAA 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 307 QTGHLVLSTLHTNSTSETLIRLQQMGVARWMISSALTLVVAQRLVRKLCPHCKQrlsdPVVLSPNLW---------PSAL 377
Cdd:COG2804 405 LTGHLVLSTLHTNDAPSAITRLLDMGVEPFLLASSLLGVLAQRLVRRLCPHCKE----PYEPDPEELerlglppeeLAPL 480
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 378 PRWQANGCQHCYH-GFYGRTALFEVLTVTPALRQLIASGASAQALEAHLQQTGTGTLFENGCRAVEQGMTSFEEILRVLG 456
Cdd:COG2804 481 TFYRGVGCEHCNGtGYKGRTGIYELLVIDDELRELIAEGASAAELREAARKEGMRTLREDGLEKVLQGITTLEEVLRVTG 560
|
.
gi 446573249 457 M 457
Cdd:COG2804 561 E 561
|
|
| type_IV_pilB |
TIGR02538 |
type IV-A pilus assembly ATPase PilB; This model describes a protein of type IV pilus ... |
9-454 |
6.15e-162 |
|
type IV-A pilus assembly ATPase PilB; This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274186 [Multi-domain] Cd Length: 564 Bit Score: 469.11 E-value: 6.15e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 9 LCQRHQAVLINSASNSITVAVVDAPSHALLDALHFATQKQIDIVCWTRQQMENHRHKP-DQAPSANAAKGGETAAQL--- 84
Cdd:TIGR02538 78 LIQKHQALPLFKRGNTLFVAVSDPTNISALDDIRFATGLNVEVVIVEEDKLSALIEKYyGGSDSLAKELGDEDIGDLeel 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 85 ---------------------------LNQTLRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARL 137
Cdd:TIGR02538 158 dvdaiddegpddieqdavdddapivkfVNKILLDAIRKGASDIHFEPYEKSYRVRFRIDGILHEVAQPPLALANRIAARI 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 138 KVLGNLDIAEHRLPQDGQFTVDLA-GDSISFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQG 216
Cdd:TIGR02538 238 KVMSRLDIAEKRIPQDGRIKLKLSkSKAIDFRVSTLPTLFGEKVVLRILDSSAAQLDIDKLGFEPDQKALFLEAIHKPQG 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 217 LVLVTGPTGSGKTVTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDG 296
Cdd:TIGR02538 318 MVLVTGPTGSGKTVSLYTALNILNTEEVNISTAEDPVEINLPGINQVNVNPKIGLTFAAALRSFLRQDPDIIMVGEIRDL 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 297 DTAEIAIKAAQTGHLVLSTLHTNSTSETLIRLQQMGVARWMISSALTLVVAQRLVRKLCPHCKQ--RLSDPVVLSPNLWP 374
Cdd:TIGR02538 398 ETAEIAIKAAQTGHLVLSTLHTNDAPETLARLVNMGIAPFNIASSVNLIMAQRLARRLCSHCKApeEVPAEALLELGFTQ 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 375 SALPRWQ---ANGCQHC-YHGFYGRTALFEVLTVTPALRQLIASGASAQALEAHLQQTGTGTLFENGCRAVEQGMTSFEE 450
Cdd:TIGR02538 478 EDLADLKlygPVGCDECsNTGYKGRVGIYEVMPMSEEIAELILKGGNALQIAELAQKEGMRTLRRSGLLKVKQGVTSLEE 557
|
....
gi 446573249 451 ILRV 454
Cdd:TIGR02538 558 VLRV 561
|
|
| type_II_gspE |
TIGR02533 |
type II secretion system protein E; This family describes GspE, the E protein of the type II ... |
84-454 |
2.04e-144 |
|
type II secretion system protein E; This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 131585 [Multi-domain] Cd Length: 486 Bit Score: 421.79 E-value: 2.04e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 84 LLNQTLRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIAEHRLPQDGQFTVDLAGD 163
Cdd:TIGR02533 111 LVNSLLSRAVKERASDIHIEPFEKALVVRFRVDGVLRDVLSPPKKLHAALVSRVKIMAKLNIAEKRLPQDGRISLRVGGR 190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 164 SISFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQGLVLVTGPTGSGKTVTLYSALQTRNTPG 243
Cdd:TIGR02533 191 DIDIRVSTVPTSHGERVVMRLLDKTAVRLDLETLGMSPELLSRFERLIRRPHGIILVTGPTGSGKTTTLYAALSRLNTPE 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 244 INLCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSE 323
Cdd:TIGR02533 271 RNILTVEDPVEYQIEGIGQIQVNPKIGLTFAAGLRAILRQDPDIIMVGEIRDLETAQIAIQASLTGHLVLSTLHTNDAAG 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 324 TLIRLQQMGVARWMISSALTLVVAQRLVRKLCPHCK-QRLSDPVVLSPNLWPSALPR--WQANGCQHCYH-GFYGRTALF 399
Cdd:TIGR02533 351 AVTRLIDMGVEPFLLASSLLGVLAQRLVRRLCPHCKePYEATPEEIALFGISPEGPInlYRPVGCPHCNHtGYLGRTGIY 430
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 446573249 400 EVLTVTPALRQLIASGASAQALEAHLQQTGTGTLFENGCRAVEQGMTSFEEILRV 454
Cdd:TIGR02533 431 ELLIVDDDLRSLIHSRADEGEIKEIARAAGMRTLRDDGLRKVLAGITTIEEVLRV 485
|
|
| T2SSE |
pfam00437 |
Type II/IV secretion system protein; This family contains components of both the Type II ... |
86-354 |
4.04e-126 |
|
Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.
Pssm-ID: 425681 [Multi-domain] Cd Length: 269 Bit Score: 366.99 E-value: 4.04e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 86 NQTLRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIAEHRLPQDGQFTVDLAGDSI 165
Cdd:pfam00437 1 NLIPLEALDEGASDIHVEPPERIVWIRFRVDGVLREIPFPDADALARLISRIKVMARLDISERRPPQDGRLPLRIGGKGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 166 SFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQGLVLVTGPTGSGKTVTLYSALQTRNTPGIN 245
Cdd:pfam00437 81 RVRVSTLPTAGGEKLVIRLLDPSNVALSLDELGMTGAQDEALLEFLRQPRGNILVTGPTGSGKTTTLYAALGELNTRDEN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 246 LCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETL 325
Cdd:pfam00437 161 IVTVEDPVEIQLEGINQVQLNARAGVTFADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHTNSAAGAL 240
|
250 260
....*....|....*....|....*....
gi 446573249 326 IRLQQMGVARWMISSALTLVVAQRLVRKL 354
Cdd:pfam00437 241 TRLQDMGVPPFELASSLLLVIAQRLVRKL 269
|
|
| ATPase_ComGA |
NF041000 |
competence type IV pilus ATPase ComGA; |
89-351 |
2.18e-94 |
|
competence type IV pilus ATPase ComGA;
Pssm-ID: 468930 [Multi-domain] Cd Length: 265 Bit Score: 285.88 E-value: 2.18e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 89 LRSAMAKRASDIHLEPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIAEHRLPQDGQFTVDLAGDSISFR 168
Cdd:NF041000 4 IEEAIELRASDIHFLPREDGYQIKFRIGGGLIPYRELSLEEGQRLISYFKFLAGMDIGEKRRPQSGAFTYELNEQQISLR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 169 IATLPCKEG-EKVVLRLLHQVEQTLDLDtlgMYGAQLTAFRQALQQPQGLVLVTGPTGSGKTVTLYSALQtRNTPGINLC 247
Cdd:NF041000 84 LSTVGDFLGrESLVIRLLYQLEQIKPQL---FFPEQFQLLKQLLQRRSGLILFSGPTGSGKTTTMYSLAR-KLALNKQVI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 248 SVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIR 327
Cdd:NF041000 160 TIEDPVEIKEPNFLQLQVNEKAGMTYDTLLKAALRHRPDILIIGEIRDAETAKAAIRAALTGHLVLSTVHAKSAAGVIYR 239
|
250 260
....*....|....*....|....
gi 446573249 328 LQQMGVARWMISSALTLVVAQRLV 351
Cdd:NF041000 240 LLELGISKEELEQTLIGISYQRLI 263
|
|
| PulE-GspE-like |
cd01129 |
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ... |
207-353 |
5.33e-82 |
|
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.
Pssm-ID: 410873 [Multi-domain] Cd Length: 159 Bit Score: 250.10 E-value: 5.33e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 207 FRQALQQPQGLVLVTGPTGSGKTVTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNVLRALLRQDPD 286
Cdd:cd01129 3 LRRLIKRPHGLILVTGPTGSGKTTTLYAMLRELNGPERNIITIEDPVEYQIPGINQSQVNEKIGLTFADALRAILRQDPD 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446573249 287 IIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIRLQQMGVARWMISSALTLVVAQRLVRK 353
Cdd:cd01129 83 IIMVGEIRDAETAEIAIRAALTGHLVLSTLHTNDALGAITRLLDMGIEPFLLASALRGVIAQRLVGR 149
|
|
| PilT |
COG2805 |
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular ... |
85-453 |
2.21e-66 |
|
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular structures];
Pssm-ID: 442056 Cd Length: 342 Bit Score: 216.11 E-value: 2.21e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 85 LNQTLRSAMAKRASDIHLEPGAsryRIRLRIDGVLHILQD----------IAKE-TGLALTARLKVLGNLDIAehrlpqd 153
Cdd:COG2805 5 LDELLKLAVEQGASDLHLTVGS---PPMLRIDGELVPLDDppltpedleaLLKEiLTEEQRERLEEEGELDFS------- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 154 gqFTVDlagDSISFRIATLPCKEGEKVVLRLLHqvEQTLDLDTLGMygaqLTAFRQALQQPQGLVLVTGPTGSGKTVTLY 233
Cdd:COG2805 75 --YSLP---GLGRFRVNIFRQRGGVAAVLRLIP--SEIPTLEELGL----PPVLKELAELPRGLVLVTGPTGSGKSTTLA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 234 SALQTRN-TPGINLCSVEDPIEIPLDG----INQTQIHPRAgLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQT 308
Cdd:COG2805 144 AMIDYINeTRAKHIITIEDPIEFVHKHkkslINQREVGRDT-PSFANALRAALREDPDVILVGEMRDLETIEAALTAAET 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 309 GHLVLSTLHTNSTSETLIRL-------QQMGVaRWMISSALTLVVAQRLVRKlcphckqrlsdpvvlspnlwpsalprwq 381
Cdd:COG2805 223 GHLVFATLHTNSAAQTIDRIidvfppeEQAQI-RSQLAESLRGVISQRLLPR---------------------------- 273
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446573249 382 ANGcqhcyhgfYGRTALFEVLTVTPALRQLIASGASAQaLEAHLQ---QTGTGTLFENGCRAVEQGMTSFEEILR 453
Cdd:COG2805 274 ADG--------GGRVAAREILVNTPAVRNLIREGKTHQ-IPSLIQtgkKLGMQTMDQSLAELVKEGLITEETALA 339
|
|
| pilT_fam |
TIGR01420 |
pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to ... |
85-460 |
4.20e-55 |
|
pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to GspE, a protein involved in type II secretion (also called the General Secretion Pathway). PilT is an apparent cytosolic ATPase associated with type IV pilus systems. It is not required for pilin biogenesis, but is required for twitching motility and social gliding behaviors, shown in some species, powered by pilus retraction. Members of this family may be found in some species that type IV pili but have related structures for DNA uptake and natural transformation. [Cell envelope, Surface structures, Cellular processes, Chemotaxis and motility]
Pssm-ID: 273613 Cd Length: 343 Bit Score: 186.76 E-value: 4.20e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 85 LNQTLRSAMAKRASDIHLEPGASRYrirLRIDGVLhILQDIAKETGLALTARLKVLGNLDIAEhRLPQDGQftVDLA--- 161
Cdd:TIGR01420 2 LEEILREAVKLGASDIHLTAGAPPA---MRIDGDL-VRIEFEPLTPEDTQKLAREILSEKQRE-EFEENGE--LDFSfsl 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 162 GDSISFRIATLPCKEGEKVVLRLLHqvEQTLDLDTLGMygaqLTAFRQALQQPQGLVLVTGPTGSGKTVTLYSALQTRN- 240
Cdd:TIGR01420 75 PGVGRFRVNAFYQRGGVALVLRLIP--SKIPTFEELGL----PPVLRELAERPRGLILVTGPTGSGKSTTLASMIDYINk 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 241 TPGINLCSVEDPIEIPLDG----INQTQIHpRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTL 316
Cdd:TIGR01420 149 NKAYHIITIEDPIEYVHTNkrslINQREVG-EDTLSFANALRAALREDPDVILIGEMRDLETVELALTAAETGHLVFGTL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 317 HTNSTSETLIRL------QQMGVARWMISSALTLVVAQRLVRKlcphckqrlsdpvvlspnlwpsalprwqANGcqhcyh 390
Cdd:TIGR01420 228 HTNSAAQTIERIidvfpaEEQEQIRTQLAESLVAIISQRLLPK----------------------------ADG------ 273
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446573249 391 gfYGRTALFEVLTVTPALRQLIASGASAQALEAHL--QQTGTGTLFENGCRAVEQGMTSFEEILRVLGMPHE 460
Cdd:TIGR01420 274 --GGRVLAVEILINTPAVRNLIREGKTHQIKSLIQtgQQLGMQTFDQHLAQLYKKGLITLEDALEAAPSPHE 343
|
|
| PilT |
cd01131 |
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein ... |
192-452 |
3.60e-51 |
|
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility.
Pssm-ID: 410875 [Multi-domain] Cd Length: 223 Bit Score: 172.72 E-value: 3.60e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 192 LDLDTLGMYgaqlTAFRQALQQPQGLVLVTGPTGSGKTVTLYSALQTRN-TPGINLCSVEDPIE--------IpldgINQ 262
Cdd:cd01131 2 PTFEELGLP----PVLKDLALKPRGLVLVTGPTGSGKSTTLAAMIDYINeTRSKHIITIEDPIEfvhkhkksL----INQ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 263 TQIHpRAGLTFQNVLRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIRL------QQMGVARW 336
Cdd:cd01131 74 REVG-RDTESFAAALRAALREDPDVILVGEMRDLETIELALTAAETGHLVFSTLHTNSAAQTIDRIidvfppEQQEQVRI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 337 MISSALTLVVAQRLVRKlcphckqrlsdpvvlspnlwpsalprwqangcqhcyHGFYGRTALFEVLTVTPALRQLIASGA 416
Cdd:cd01131 153 QLASSLRGVISQRLLPK------------------------------------KDGGGRVAAFEILINTPAIRNLIREGK 196
|
250 260 270
....*....|....*....|....*....|....*.
gi 446573249 417 SAQaLEAHLqQTGTgtlfengcravEQGMTSFEEIL 452
Cdd:cd01131 197 THQ-IPSLI-QTGA-----------RDGMQTMDQSL 219
|
|
| DotB_TraJ |
cd19516 |
dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of ... |
216-353 |
1.29e-36 |
|
dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of the type IVb secretion (T4bS) system, also known as the dot/icm system, and is the main energy supplier of the secretion system. It is an ATPase, similar to the VirB11 component of the T4aS systems. This family also includes Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ encoded on the tra (transfer) operon.
Pssm-ID: 410924 [Multi-domain] Cd Length: 179 Bit Score: 132.89 E-value: 1.29e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 216 GLVLVTGPTGSGKTVTL---YSALQTRNTPGINLCSVEDPIEIPLDGIN-------QTQIhPRAGLTFQNVLRALLRQDP 285
Cdd:cd19516 12 GLVYVAGATGSGKSTLLaaiYRYILENDPPDRKIITYEDPIEFVYDGIKskhsiivQSQI-PRHFKSFAKAVREALRRKP 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446573249 286 DIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIRL-------QQMGVArWMISSALTLVVAQRLVRK 353
Cdd:cd19516 91 SLIGVGELRDQETISAAVEASLTGHPVYSTVHTKSVAETIRRLislfppeERDAAA-YDLLSTLRFIIVQRLVRT 164
|
|
| type_II_IV_secretion_ATPases |
cd19477 |
type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP ... |
205-354 |
3.51e-35 |
|
type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410885 [Multi-domain] Cd Length: 168 Bit Score: 128.67 E-value: 3.51e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 205 TAFRQALQQPqGLVLVTGPTGSGKTVTLYSALQTRNTPGiNLCSVEDPIEIPL---DGINQTQIHPRagLTFQNVLRALL 281
Cdd:cd19477 1 SAIKDGIAIG-KNVIVCGGTGSGKTTYIKSILEFIPKEE-RIISIEDTEEIVFkhhKNYTQLFFGGN--ITSADCLKSCL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 282 RQDPDIIMVGEIRDgDTAEIAIKAAQTGH-LVLSTLHTNSTSETLIRLQQMGVAR------------WMISSALTLVVAQ 348
Cdd:cd19477 77 RQRPDRIILGELRS-SEAYDFYNVLCSGHkGTLTTLHAGSSEEAFIRLAN*SSSNsaarnikfesliEGFKDLIDGIVHI 155
|
....*.
gi 446573249 349 RLVRKL 354
Cdd:cd19477 156 NHHKQC 161
|
|
| PilU |
COG5008 |
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures]; |
216-453 |
3.86e-32 |
|
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];
Pssm-ID: 444032 Cd Length: 370 Bit Score: 125.98 E-value: 3.86e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 216 GLVLVTGPTGSGKTVTLYSALQTRNTpgiNLC----SVEDPIE--------IpldgINQTQIhpraGL---TFQNVLRAL 280
Cdd:COG5008 124 GLVLFVGATGSGKSTTLAAMIDHRNE---NSSghilTIEDPIEfvhkhkksI----VTQREV----GVdteSYEVALKNA 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 281 LRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIRL---------QQMgvarWM-ISSALTLVVAQRL 350
Cdd:COG5008 193 LRQAPDVILIGEIRDRETMEHAIAFAETGHLCLATLHANNANQALDRIinffpeerrPQL----LMdLSLNLRAIVSQRL 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 351 VRKlcphckqrlsdpvvlspnlwpsalprwqANGcqhcyhgfyGRTALFEVLTVTPALRQLIASG-------ASAQALEA 423
Cdd:COG5008 269 VPT----------------------------KDG---------GRVAAVEVLLNTPLIADLIRKGeiheikeAMEKSREL 311
|
250 260 270
....*....|....*....|....*....|
gi 446573249 424 HLqQTGTGTLFengcRAVEQGMTSFEEILR 453
Cdd:COG5008 312 GM-QTFDQALF----RLYEAGKISYEEALR 336
|
|
| plasmid_TraJ |
TIGR02525 |
plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated ... |
209-352 |
5.73e-23 |
|
plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated with plasmid transfer loci in bacteria. This family is most similar to the DotB ATPase of a type-IV secretion-like system of obligate intracellular pathogens Legionella pneumophila and Coxiella burnetii (TIGR02524). [Mobile and extrachromosomal element functions, Plasmid functions]
Pssm-ID: 131577 [Multi-domain] Cd Length: 372 Bit Score: 99.88 E-value: 5.73e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 209 QALQQPQGLVLVTGPTGSGKTVTLYSALQ--TRNTPGINLCSVEDPIEIPLDGIN------QTQIHpRAGLTFQNVLRAL 280
Cdd:TIGR02525 143 NSLLPAAGLGLICGETGSGKSTLAASIYQhcGETYPDRKIVTYEDPIEYILGSPDdllppaQSQIG-RDVDSFANGIRLA 221
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446573249 281 LRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIRLQQM------GVARWMISSALTLVVAQRLVR 352
Cdd:TIGR02525 222 LRRAPKIIGVGEIRDLETFQAAVLAGQSGHFCLGTLHVKSPGEAISRCLQMyppemrEAAAFDLLSILQYIIVQRLLR 299
|
|
| VirB11 |
COG0630 |
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell ... |
218-352 |
9.51e-20 |
|
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440395 [Multi-domain] Cd Length: 462 Bit Score: 91.30 E-value: 9.51e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 218 VLVTGPTGSGKTvTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQIHPR--AGLTFQNV-----LRALLRQDPDIIMV 290
Cdd:COG0630 293 VLVAGGTASGKT-TLLNALLSFIPPDAKIVTIEDTRELNLPHENWISLVTResFGGEEGDVtmfdlLKAALRQRPDYIVV 371
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446573249 291 GEIRdGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIRLQQ--MGVARWMIsSALTLVVAQRLVR 352
Cdd:COG0630 372 GEVR-GEEAYTLFQAMATGHGVLSTFHADSVESAINRLTSppINVPRTLL-QALDLVVFQKRVR 433
|
|
| VirB11-like_ATPase |
cd01130 |
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ... |
203-346 |
1.60e-19 |
|
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.
Pssm-ID: 410874 [Multi-domain] Cd Length: 177 Bit Score: 85.67 E-value: 1.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 203 QLTAFRQALQQPQGlVLVTGPTGSGKTvTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQI------HPRAGLTFQNV 276
Cdd:cd01130 1 MAAFLRLAVRARKN-ILISGGTGSGKT-TLLNALLSFIPPDERIVTIEDTRELQLPHPNVVHLltrpggGEKGEVTMADL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 277 LRALLRQDPDIIMVGEIRdGDTAEIAIKAAQTGHL-VLSTLHTNSTSETLIRLQQMG----------VARWMISSALTLV 345
Cdd:cd01130 79 LKAALRMRPDRIIVGEVR-GGEAYDMLQAMNTGHPgSITTIHANSAEDAIDRLATLVleagvnldeeALRRLIASAIDVI 157
|
.
gi 446573249 346 V 346
Cdd:cd01130 158 V 158
|
|
| PRK13894 |
PRK13894 |
conjugal transfer ATPase TrbB; Provisional |
199-328 |
4.36e-12 |
|
conjugal transfer ATPase TrbB; Provisional
Pssm-ID: 184377 Cd Length: 319 Bit Score: 66.69 E-value: 4.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 199 MYGAQLTAFRQALQQPQGlVLVTGPTGSGKTvTLYSAL---QTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQN 275
Cdd:PRK13894 133 MTAAQREAIIAAVRAHRN-ILVIGGTGSGKT-TLVNAIineMVIQDPTERVFIIEDTGEIQCAAENYVQYHTSIDVNMTA 210
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 446573249 276 VLRALLRQDPDIIMVGEIRdGDTAEIAIKAAQTGHL-VLSTLHTNSTSETLIRL 328
Cdd:PRK13894 211 LLKTTLRMRPDRILVGEVR-GPEALDLLMAWNTGHEgGAATLHANNAKAGLDRL 263
|
|
| VirB11 |
TIGR02788 |
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of ... |
207-331 |
6.97e-12 |
|
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.
Pssm-ID: 274301 Cd Length: 308 Bit Score: 66.22 E-value: 6.97e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 207 FRQALQQPQGLVlVTGPTGSGKTvTLYSALqTRNTPGIN-LCSVEDPIEIPLDGINQTQI------HPRAGLTFQNVLRA 279
Cdd:TIGR02788 137 LRLAIASRKNII-ISGGTGSGKT-TFLKSL-VDEIPKDErIITIEDTREIFLPHPNYVHLfyskggQGLAKVTPKDLLQS 213
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 446573249 280 LLRQDPDIIMVGEIRdGDTAEIAIKAAQTGHL-VLSTLHTNSTSETLIRLQQM 331
Cdd:TIGR02788 214 CLRMRPDRIILGELR-GDEAFDFIRAVNTGHPgSITTLHAGSPEEAFEQLALM 265
|
|
| PRK13833 |
PRK13833 |
conjugal transfer protein TrbB; Provisional |
199-331 |
1.86e-11 |
|
conjugal transfer protein TrbB; Provisional
Pssm-ID: 172360 [Multi-domain] Cd Length: 323 Bit Score: 64.82 E-value: 1.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 199 MYGAQLTAFRQALQQPQGLVlVTGPTGSGKTvTLYSAL---QTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQN 275
Cdd:PRK13833 129 MTEAQASVIRSAIDSRLNIV-ISGGTGSGKT-TLANAViaeIVASAPEDRLVILEDTAEIQCAAENAVALHTSDTVDMAR 206
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 446573249 276 VLRALLRQDPDIIMVGEIRDGdTAEIAIKAAQTGHL-VLSTLHTNSTSETLIRLQQM 331
Cdd:PRK13833 207 LLKSTMRLRPDRIIVGEVRDG-AALTLLKAWNTGHPgGVTTIHSNTAMSALRRLEQL 262
|
|
| PRK13900 |
PRK13900 |
type IV secretion system ATPase VirB11; Provisional |
218-331 |
8.14e-08 |
|
type IV secretion system ATPase VirB11; Provisional
Pssm-ID: 184381 Cd Length: 332 Bit Score: 53.99 E-value: 8.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 218 VLVTGPTGSGKTVTLYSALqtRNTPGIN-LCSVEDPIEIPLDGinqtqiHP-------------RAGLTFQNVLRALLRQ 283
Cdd:PRK13900 163 IIISGGTSTGKTTFTNAAL--REIPAIErLITVEDAREIVLSN------HPnrvhllaskggqgRAKVTTQDLIEACLRL 234
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 446573249 284 DPDIIMVGEIRdGDTAEIAIKAAQTGHL-VLSTLHTNSTSETLIRLQQM 331
Cdd:PRK13900 235 RPDRIIVGELR-GAEAFSFLRAINTGHPgSISTLHADSPAMAIEQLKLM 282
|
|
| PRK13851 |
PRK13851 |
type IV secretion system protein VirB11; Provisional |
204-317 |
6.59e-07 |
|
type IV secretion system protein VirB11; Provisional
Pssm-ID: 172375 Cd Length: 344 Bit Score: 51.05 E-value: 6.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 204 LTAFRQALQQPQGLVLVTGPTGSGKTV---TLYSALqtrnTPGINLCSVEDPIEIPLDGINQTQI------HPRAGLTFQ 274
Cdd:PRK13851 151 LEAFLHACVVGRLTMLLCGPTGSGKTTmskTLISAI----PPQERLITIEDTLELVIPHENHVRLlyskngAGLGAVTAE 226
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 446573249 275 NVLRALLRQDPDIIMVGEIRDgDTAEIAIKAAQTGHL-VLSTLH 317
Cdd:PRK13851 227 HLLQASLRMRPDRILLGEMRD-DAAWAYLSEVVSGHPgSISTIH 269
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
214-293 |
2.07e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.51 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446573249 214 PQGLVLVTGPTGSGKTVTLYSALQ--TRNTPGINLCSVEDPIEIPLDGINQTQIHPRA-----GLTFQNVLRALLRQDPD 286
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARelGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKasgsgELRLRLALALARKLKPD 80
|
....*..
gi 446573249 287 IIMVGEI 293
Cdd:smart00382 81 VLILDEI 87
|
|
| T2SSE_N |
pfam05157 |
Type II secretion system (T2SS), protein E, N-terminal domain; This domain is found at the ... |
9-52 |
2.27e-03 |
|
Type II secretion system (T2SS), protein E, N-terminal domain; This domain is found at the N-terminus of members of the Type II secretion system protein E. Proteins in this subfamily are typically involved in Type 4 pilus biogenesis, though some are involved in other processes; for instance aggregation in Myxococcus xanthus. The structure of this domain is now known.
Pssm-ID: 428339 [Multi-domain] Cd Length: 108 Bit Score: 37.70 E-value: 2.27e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 446573249 9 LCQRHQAVLINSASNSITVAVVDAPSHALLDALHFATQKQIDIV 52
Cdd:pfam05157 44 FARRHRVLPLREDGGTLVVAVADPLDLALLDELRFLTGKRVEPV 87
|
|
| DEXXQc_UPF1 |
cd18039 |
DEXXQ-box helicase domain of UPF1; UPF1 (also called RNA Helicase And ATPase, Regulator Of ... |
203-231 |
8.27e-03 |
|
DEXXQ-box helicase domain of UPF1; UPF1 (also called RNA Helicase And ATPase, Regulator Of Nonsense Transcripts, or ATP-Dependent Helicase RENT1) is an RNA-dependent helicase and ATPase required for nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. It is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. It is recruited by release factors to stalled ribosomes together with the SMG1C protein kinase complex to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex. In EJC-dependent NMD, the SURF complex associates with the exon junction complex (EJC) located downstream from the termination codon through UPF2 and allows the formation of an UPF1-UPF2-UPF3 surveillance complex which is believed to activate NMD. Diseases associated with UPF1 include juvenile amyotrophic lateral sclerosis and epidermolysis bullosa, junctional, non-Herlitz type. UPF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350797 [Multi-domain] Cd Length: 234 Bit Score: 37.61 E-value: 8.27e-03
10 20
....*....|....*....|....*....
gi 446573249 203 QLTAFRQALQQPqgLVLVTGPTGSGKTVT 231
Cdd:cd18039 6 QVDAVKTALQRP--LSLIQGPPGTGKTVT 32
|
|
| |
