|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10437 |
PRK10437 |
carbonic anhydrase; Provisional |
1-220 |
9.39e-180 |
|
carbonic anhydrase; Provisional
Pssm-ID: 182460 Cd Length: 220 Bit Score: 490.98 E-value: 9.39e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 1 MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSV 80
Cdd:PRK10437 1 MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 81 VQYAVDVLEVEHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPPERRLDTLCELNVMEQVYNLGH 160
Cdd:PRK10437 81 VQYAVDVLEVEHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 161 STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHINHK 220
Cdd:PRK10437 161 STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHANHK 220
|
|
| beta_CA_cladeA |
cd00883 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
11-191 |
1.52e-112 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238448 Cd Length: 182 Bit Score: 319.51 E-value: 1.52e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 11 NALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEV 90
Cdd:cd00883 1 NRAWAEEKKAKDPDFFPRLAKGQTPEYLWIGCSDSRVPENTILGLLPGEVFVHRNIANLVSPTDLNCLSVLQYAVDVLKV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 91 EHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEM-PPERRLDTLCELNVMEQVYNLGHSTIMQSAWK 169
Cdd:cd00883 81 KHIIVCGHYGCGGVKAALTGKRLGLLDNWLRPIRDVYRLHAAELDALeDEEERVDRLVELNVVEQVKNLCKTPIVQDAWK 160
|
170 180
....*....|....*....|..
gi 446574250 170 RGQKVTIHGWAYGIHDGLLRDL 191
Cdd:cd00883 161 RGQELEVHGWVYDLGDGLLRDL 182
|
|
| CynT |
COG0288 |
Carbonic anhydrase [Inorganic ion transport and metabolism]; |
1-202 |
1.46e-96 |
|
Carbonic anhydrase [Inorganic ion transport and metabolism];
Pssm-ID: 440057 Cd Length: 204 Bit Score: 279.74 E-value: 1.46e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 1 MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSV 80
Cdd:COG0288 1 MEALKRLLEGNRRFVAGKFPQDPERFEELAKGQHPFALVIGCSDSRVPPELIFDQGPGDLFVVRNAGNVVPPYDPGVLAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 81 VQYAVDVLEVEHIIICGHYGCGGVQAAVEN---PELGLINNWLLHIRDIWFKHSSLLGEMPPERRLDTLCELNVMEQVYN 157
Cdd:COG0288 81 IEYAVEVLGVKLIVVLGHSGCGAVKAALDGlelEELGLIGNWLRHIRPAVERVRAELPAADGEERLDRLVELNVREQVEN 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446574250 158 LGHSTIMQSAWKRGQkVTIHGWAYGIHDGLLRDLDVTATNRETLE 202
Cdd:COG0288 161 LRTSPIVREAVAAGK-LKVHGWVYDLATGRVEFLDPEGGGFEPLP 204
|
|
| Pro_CA |
pfam00484 |
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of ... |
38-188 |
4.08e-76 |
|
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of non-functional homologs related to YbcF.
Pssm-ID: 459828 Cd Length: 156 Bit Score: 226.24 E-value: 4.08e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 38 LWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCGGVQAAVENP----EL 113
Cdd:pfam00484 2 LIIGCSDSRVPPELIFDTGPGDLFVVRNAGNLVPPYDLNVLASIEYAVEVLKVKHIVVCGHSGCGAVKAALDAAgpaeLP 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446574250 114 GLINNWLLHIRDIWFKHSSLLGEM-PPERRLDTLCELNVMEQVYNLGHSTIMQSAWKRGQkVTIHGWAYGIHDGLL 188
Cdd:pfam00484 82 GFIDNWLRHIRPAVERVAEELESLdDPEERDDALEELNVREQVENLRTFPIVREAVAKGK-LKIHGWVYDLETGEV 156
|
|
| Pro_CA |
smart00947 |
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the ... |
30-191 |
2.93e-70 |
|
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (gene cynS). By this action, it prevents the depletion of cellular bicarbonate. In photosynthetic bacteria and plant chloroplast, CA is essential to inorganic carbon fixation. Prokaryotic and plant chloroplast CA are structurally and evolutionary related and form a family distinct from the one which groups the many different forms of eukaryotic CA's.
Pssm-ID: 214929 [Multi-domain] Cd Length: 154 Bit Score: 211.21 E-value: 2.93e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 30 AQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCGGVQAAVE 109
Cdd:smart00947 1 AKGQHPKALIIGCSDSRVPPELIFGLGPGDLFVIRNAGNIVPPYDDGVLASLEYAVEVLGVKEIVVCGHTDCGAVKAALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 110 nPELGLINNWLLHIRDIWFKHSSLLGEMpperrlDTLCELNVMEQVYNLGHSTIMQSAWKRGqKVTIHGWAYGIHDGLLR 189
Cdd:smart00947 81 -DEPGLIDNWLERIRPARERALEELGDV------DALEELNVRDQVENLRTSPAIREAVAKG-KLKVHGWVYDIETGKLE 152
|
..
gi 446574250 190 DL 191
Cdd:smart00947 153 VL 154
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10437 |
PRK10437 |
carbonic anhydrase; Provisional |
1-220 |
9.39e-180 |
|
carbonic anhydrase; Provisional
Pssm-ID: 182460 Cd Length: 220 Bit Score: 490.98 E-value: 9.39e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 1 MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSV 80
Cdd:PRK10437 1 MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 81 VQYAVDVLEVEHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPPERRLDTLCELNVMEQVYNLGH 160
Cdd:PRK10437 81 VQYAVDVLEVEHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 161 STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHINHK 220
Cdd:PRK10437 161 STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHANHK 220
|
|
| beta_CA_cladeA |
cd00883 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
11-191 |
1.52e-112 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238448 Cd Length: 182 Bit Score: 319.51 E-value: 1.52e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 11 NALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEV 90
Cdd:cd00883 1 NRAWAEEKKAKDPDFFPRLAKGQTPEYLWIGCSDSRVPENTILGLLPGEVFVHRNIANLVSPTDLNCLSVLQYAVDVLKV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 91 EHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEM-PPERRLDTLCELNVMEQVYNLGHSTIMQSAWK 169
Cdd:cd00883 81 KHIIVCGHYGCGGVKAALTGKRLGLLDNWLRPIRDVYRLHAAELDALeDEEERVDRLVELNVVEQVKNLCKTPIVQDAWK 160
|
170 180
....*....|....*....|..
gi 446574250 170 RGQKVTIHGWAYGIHDGLLRDL 191
Cdd:cd00883 161 RGQELEVHGWVYDLGDGLLRDL 182
|
|
| CynT |
COG0288 |
Carbonic anhydrase [Inorganic ion transport and metabolism]; |
1-202 |
1.46e-96 |
|
Carbonic anhydrase [Inorganic ion transport and metabolism];
Pssm-ID: 440057 Cd Length: 204 Bit Score: 279.74 E-value: 1.46e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 1 MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSV 80
Cdd:COG0288 1 MEALKRLLEGNRRFVAGKFPQDPERFEELAKGQHPFALVIGCSDSRVPPELIFDQGPGDLFVVRNAGNVVPPYDPGVLAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 81 VQYAVDVLEVEHIIICGHYGCGGVQAAVEN---PELGLINNWLLHIRDIWFKHSSLLGEMPPERRLDTLCELNVMEQVYN 157
Cdd:COG0288 81 IEYAVEVLGVKLIVVLGHSGCGAVKAALDGlelEELGLIGNWLRHIRPAVERVRAELPAADGEERLDRLVELNVREQVEN 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446574250 158 LGHSTIMQSAWKRGQkVTIHGWAYGIHDGLLRDLDVTATNRETLE 202
Cdd:COG0288 161 LRTSPIVREAVAAGK-LKVHGWVYDLATGRVEFLDPEGGGFEPLP 204
|
|
| Pro_CA |
pfam00484 |
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of ... |
38-188 |
4.08e-76 |
|
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of non-functional homologs related to YbcF.
Pssm-ID: 459828 Cd Length: 156 Bit Score: 226.24 E-value: 4.08e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 38 LWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCGGVQAAVENP----EL 113
Cdd:pfam00484 2 LIIGCSDSRVPPELIFDTGPGDLFVVRNAGNLVPPYDLNVLASIEYAVEVLKVKHIVVCGHSGCGAVKAALDAAgpaeLP 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446574250 114 GLINNWLLHIRDIWFKHSSLLGEM-PPERRLDTLCELNVMEQVYNLGHSTIMQSAWKRGQkVTIHGWAYGIHDGLL 188
Cdd:pfam00484 82 GFIDNWLRHIRPAVERVAEELESLdDPEERDDALEELNVREQVENLRTFPIVREAVAKGK-LKIHGWVYDLETGEV 156
|
|
| Pro_CA |
smart00947 |
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the ... |
30-191 |
2.93e-70 |
|
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (gene cynS). By this action, it prevents the depletion of cellular bicarbonate. In photosynthetic bacteria and plant chloroplast, CA is essential to inorganic carbon fixation. Prokaryotic and plant chloroplast CA are structurally and evolutionary related and form a family distinct from the one which groups the many different forms of eukaryotic CA's.
Pssm-ID: 214929 [Multi-domain] Cd Length: 154 Bit Score: 211.21 E-value: 2.93e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 30 AQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCGGVQAAVE 109
Cdd:smart00947 1 AKGQHPKALIIGCSDSRVPPELIFGLGPGDLFVIRNAGNIVPPYDDGVLASLEYAVEVLGVKEIVVCGHTDCGAVKAALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 110 nPELGLINNWLLHIRDIWFKHSSLLGEMpperrlDTLCELNVMEQVYNLGHSTIMQSAWKRGqKVTIHGWAYGIHDGLLR 189
Cdd:smart00947 81 -DEPGLIDNWLERIRPARERALEELGDV------DALEELNVRDQVENLRTSPAIREAVAKG-KLKVHGWVYDIETGKLE 152
|
..
gi 446574250 190 DL 191
Cdd:smart00947 153 VL 154
|
|
| beta_CA |
cd00382 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
33-191 |
2.74e-53 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238224 [Multi-domain] Cd Length: 119 Bit Score: 166.91 E-value: 2.74e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 33 QKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCGGVQAavenpe 112
Cdd:cd00382 1 QKPKALIIGCSDSRVPPELIFGLGPGDLFVVRNAGNLVPPYDLDVLASLEYAVEVLGVKHIIVCGHTDCGAVKA------ 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446574250 113 lglinnwllhirdiwfkhssllgempperrldtLCELNVMEQVYNLGHSTIMQsAWKRGQKVTIHGWAYGIHDGLLRDL 191
Cdd:cd00382 75 ---------------------------------LVEENVREQVENLRSHPLIQ-EAVAPGELKVHGWVYDIETGKLEVL 119
|
|
| beta_CA_cladeB |
cd00884 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
20-188 |
3.86e-45 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238449 Cd Length: 190 Bit Score: 148.46 E-value: 3.86e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 20 EEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLV--IHTDLNCLSV---VQYAVDVLEVEHII 94
Cdd:cd00884 11 PEERELFEKLAKGQSPKALFIACSDSRVVPALITQTQPGELFVVRNVGNLVppYEPDGGFHGTsaaIEYAVAVLKVEHIV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 95 ICGHYGCGGVQAAVE----NPELGLINNWLLHIRDIWFKHSSLLGEMPPERRLDTLCELNVMEQVYNL-GHSTImQSAWK 169
Cdd:cd00884 91 VCGHSDCGGIRALLSpedlLDKLPFIGKWLRIAEPAKEVVLAELSHADFDDQLRALEKENVLLSLENLlTYPFV-RERLE 169
|
170
....*....|....*....
gi 446574250 170 RGqKVTIHGWAYGIHDGLL 188
Cdd:cd00884 170 AG-TLSLHGWYYDIETGEL 187
|
|
| PLN00416 |
PLN00416 |
carbonate dehydratase |
20-120 |
1.47e-20 |
|
carbonate dehydratase
Pssm-ID: 177809 Cd Length: 258 Bit Score: 86.63 E-value: 1.47e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 20 EEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDL----NCLSVVQYAVDVLEVEHIII 95
Cdd:PLN00416 65 LKNSTLFNHLAKTQTPKFLVFACSDSRVCPSHILNFQPGEAFVVRNIANMVPPFDQkrhsGVGAAVEYAVVHLKVENILV 144
|
90 100 110
....*....|....*....|....*....|.
gi 446574250 96 CGHYGCGGVQA--AVEN----PELGLINNWL 120
Cdd:PLN00416 145 IGHSCCGGIKGlmSIEDdaapTQSDFIENWV 175
|
|
| PLN02154 |
PLN02154 |
carbonic anhydrase |
26-185 |
4.39e-19 |
|
carbonic anhydrase
Pssm-ID: 215111 Cd Length: 290 Bit Score: 83.26 E-value: 4.39e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 26 FEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVI-----HTDLNclSVVQYAVDVLEVEHIIICGHYG 100
Cdd:PLN02154 98 FKALAIAQSPKVMVIGCADSRVCPSYVLGFQPGEAFTIRNVANLVTpvqngPTETN--SALEFAVTTLQVENIIVMGHSN 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 101 CGGVQAAV-----ENPELGLINNWLLHIRDIWFKHSSLLGEMPPERRLDTLCELNVMEQVYNLGHSTIMQSAWKRGQkVT 175
Cdd:PLN02154 176 CGGIAALMshqnhQGQHSSLVERWVMNGKAAKLRTQLASSHLSFDEQCRNCEKESIKDSVMNLITYSWIRDRVKRGE-VK 254
|
170
....*....|
gi 446574250 176 IHGWAYGIHD 185
Cdd:PLN02154 255 IHGCYYNLSD 264
|
|
| PLN03006 |
PLN03006 |
carbonate dehydratase |
14-121 |
5.73e-18 |
|
carbonate dehydratase
Pssm-ID: 178583 Cd Length: 301 Bit Score: 80.56 E-value: 5.73e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 14 WSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTD---LNCLSVVQYAVDVLEV 90
Cdd:PLN03006 92 FKKLKYMDDFEHYKNLADAQAPKFLVIACADSRVCPSAVLGFQPGDAFTVRNIANLVPPYEsgpTETKAALEFSVNTLNV 171
|
90 100 110
....*....|....*....|....*....|....*
gi 446574250 91 EHIIICGHYGCGGVQAAVENPELG----LINNWLL 121
Cdd:PLN03006 172 ENILVIGHSRCGGIQALMKMEDEGdsrsFIHNWVV 206
|
|
| beta_CA_cladeC |
cd03378 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
27-109 |
5.78e-17 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 239473 [Multi-domain] Cd Length: 154 Bit Score: 74.48 E-value: 5.78e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 27 EKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVihtDLNCLSVVQYAVDVLEVEHIIICGHYGCGGVQA 106
Cdd:cd03378 31 RELAKGQKPFAVILSCSDSRVPPEIIFDQGLGDLFVVRVAGNIV---DDDVLGSLEYAVEVLGVPLVVVLGHESCGAVAA 107
|
...
gi 446574250 107 AVE 109
Cdd:cd03378 108 AAV 110
|
|
| PLN03014 |
PLN03014 |
carbonic anhydrase |
20-129 |
1.06e-16 |
|
carbonic anhydrase
Pssm-ID: 178588 [Multi-domain] Cd Length: 347 Bit Score: 77.47 E-value: 1.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 20 EEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDL----NCLSVVQYAVDVLEVEHIII 95
Cdd:PLN03014 145 ETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKvkygGVGAAIEYAVLHLKVENIVV 224
|
90 100 110
....*....|....*....|....*....|....
gi 446574250 96 CGHYGCGGVQAAVENPELGliNNWLLHIRDiWFK 129
Cdd:PLN03014 225 IGHSACGGIKGLMSFPLDG--NNSTDFIED-WVK 255
|
|
| PLN03019 |
PLN03019 |
carbonic anhydrase |
20-129 |
7.04e-16 |
|
carbonic anhydrase
Pssm-ID: 166660 Cd Length: 330 Bit Score: 74.80 E-value: 7.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 20 EEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTD----LNCLSVVQYAVDVLEVEHIII 95
Cdd:PLN03019 140 ETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFHPGDAFVVRNIANMVPPFDkvkyAGVGAAIEYAVLHLKVENIVV 219
|
90 100 110
....*....|....*....|....*....|....
gi 446574250 96 CGHYGCGGVQAAVENPELGliNNWLLHIRDiWFK 129
Cdd:PLN03019 220 IGHSACGGIKGLMSFPLDG--NNSTDFIED-WVK 250
|
|
| PRK15219 |
PRK15219 |
carbonic anhydrase; Provisional |
30-186 |
4.66e-09 |
|
carbonic anhydrase; Provisional
Pssm-ID: 237927 [Multi-domain] Cd Length: 245 Bit Score: 54.84 E-value: 4.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 30 AQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRnVANLVIHTDLncLSVVQYAVDVLEVEHIIICGHYGCGGVQAAVE 109
Cdd:PRK15219 85 AAGQYPAAVILSCIDSRAPAEIILDTGIGETFNSR-VAGNISNDDL--LGSMEFACAVAGAKVVLVMGHTACGAVKGAID 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 110 NPELGLINNWLLHIrdiwfKHSSLLGEMPPERR------LDTLCELNVMEQVYNL-GHSTIMQSAWKRGqKVTIHGWAYG 182
Cdd:PRK15219 162 NVELGNLTGLLDRI-----KPAIEVTEFDGERSsknykfVDAVARKNVELTIENIrKNSPILRKLEQEG-KIKIVGSMYN 235
|
....
gi 446574250 183 IHDG 186
Cdd:PRK15219 236 LNGG 239
|
|
| beta_CA_cladeD |
cd03379 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
34-189 |
1.05e-05 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 239474 Cd Length: 142 Bit Score: 43.78 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446574250 34 KPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAvdvLEVEHIIICGHYGCGgvQAAVENPEL 113
Cdd:cd03379 2 ARKLAIVTCMDARLDPEKALGLKLGDAKVIRNAGGRVTDDAIRSLVVSVYL---LGTREIIVIHHTDCG--MLTFTDEEL 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446574250 114 --GLINNWLLHIRDIWFKHSSLLGempperrLDTLCElNVMEQVYNLGHSTIMQSawkrgqKVTIHGWAYGIHDGLLR 189
Cdd:cd03379 77 keKMKERGIAEAYGGIDKEFWFLG-------FDDLEE-SVREDVERIRNHPLIPD------DVPVHGYVYDVKTGKLT 140
|
|
|