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Conserved domains on  [gi|446587372|ref|WP_000664718|]
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MULTISPECIES: transglycosylase domain-containing protein [Bacillus]

Protein Classification

transglycosylase domain-containing protein( domain architecture ID 11432910)

transglycosylase domain-containing protein catalyzes the polymerization of murein glycan chains; such as biosynthetic peptidoglycan transglycosylase and bifunctional penicillin-binding proteins

CAZY:  GT51
EC:  2.4.-.-
PubMed:  8830253
SCOP:  4002510

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MrcB COG0744
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
42-239 3.78e-98

Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440507 [Multi-domain]  Cd Length: 630  Bit Score: 299.53  E-value: 3.78e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  42 GNVMIEQSDISKLHVPAKlEVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTN 121
Cdd:COG0744   63 GTLIATLGDENREWVPLD-QIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSN 141
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 122 ERTFSRKWKEIFYTKKIERTFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQ 201
Cdd:COG0744  142 ERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYR 221
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446587372 202 NYDKAVERRNVVLRLMEKEGYISHDEYVQAVSEKLVIR 239
Cdd:COG0744  222 NPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLV 259
 
Name Accession Description Interval E-value
MrcB COG0744
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
42-239 3.78e-98

Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440507 [Multi-domain]  Cd Length: 630  Bit Score: 299.53  E-value: 3.78e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  42 GNVMIEQSDISKLHVPAKlEVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTN 121
Cdd:COG0744   63 GTLIATLGDENREWVPLD-QIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSN 141
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 122 ERTFSRKWKEIFYTKKIERTFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQ 201
Cdd:COG0744  142 ERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYR 221
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446587372 202 NYDKAVERRNVVLRLMEKEGYISHDEYVQAVSEKLVIR 239
Cdd:COG0744  222 NPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLV 259
PBP_1a_fam TIGR02074
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ...
61-237 1.88e-84

penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 273955 [Multi-domain]  Cd Length: 531  Bit Score: 261.43  E-value: 1.88e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372   61 EVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTNERTFSRKWKEIFYTKKIER 140
Cdd:TIGR02074   9 DIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEALLALKLEQ 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  141 TFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRNVVLRLMEKE 220
Cdd:TIGR02074  89 KLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNLVLSNMVEN 168
                         170
                  ....*....|....*..
gi 446587372  221 GYISHDEYVQAVSEKLV 237
Cdd:TIGR02074 169 GYITAEEAEEAINEPIQ 185
Transgly pfam00912
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ...
42-218 1.26e-83

Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.


Pssm-ID: 459993 [Multi-domain]  Cd Length: 177  Bit Score: 247.44  E-value: 1.26e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372   42 GNVMIEQSDISKLHVPAKlEVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTN 121
Cdd:pfam00912   2 GTLLAELGEENREYVPLD-DIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  122 ERTFSRKWKEIFYTKKIERTFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQ 201
Cdd:pfam00912  81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
                         170
                  ....*....|....*..
gi 446587372  202 NYDKAVERRNVVLRLME 218
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
mrcA PRK11636
penicillin-binding protein 1a; Provisional
53-240 6.91e-68

penicillin-binding protein 1a; Provisional


Pssm-ID: 183248 [Multi-domain]  Cd Length: 850  Bit Score: 224.62  E-value: 6.91e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  53 KLHVPAKL-EVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTNERTFSRKWKE 131
Cdd:PRK11636  64 KRRIPLTLdQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKE 143
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 132 IFYTKKIERTFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRN 211
Cdd:PRK11636 144 AFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRN 223
                        170       180
                 ....*....|....*....|....*....
gi 446587372 212 VVLRLMEKEGYISHDEYVQAVSEKLVIRH 240
Cdd:PRK11636 224 VVLSRMLDEGYITQAQYDQARSEPIVANY 252
 
Name Accession Description Interval E-value
MrcB COG0744
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
42-239 3.78e-98

Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440507 [Multi-domain]  Cd Length: 630  Bit Score: 299.53  E-value: 3.78e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  42 GNVMIEQSDISKLHVPAKlEVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTN 121
Cdd:COG0744   63 GTLIATLGDENREWVPLD-QIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSN 141
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 122 ERTFSRKWKEIFYTKKIERTFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQ 201
Cdd:COG0744  142 ERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYR 221
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446587372 202 NYDKAVERRNVVLRLMEKEGYISHDEYVQAVSEKLVIR 239
Cdd:COG0744  222 NPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLV 259
MrcA COG5009
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
61-245 3.82e-93

Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 444033 [Multi-domain]  Cd Length: 785  Bit Score: 290.52  E-value: 3.82e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  61 EVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTNERTFSRKWKEIFYTKKIER 140
Cdd:COG5009   73 EIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQ 152
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 141 TFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRNVVLRLMEKE 220
Cdd:COG5009  153 ELSKDEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLEL 232
                        170       180
                 ....*....|....*....|....*.
gi 446587372 221 GYISHDEYVQAVSEKLVIR-HDIKIE 245
Cdd:COG5009  233 GYITQAEYEAAKAEPLTARyHGASAE 258
PBP_1a_fam TIGR02074
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ...
61-237 1.88e-84

penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 273955 [Multi-domain]  Cd Length: 531  Bit Score: 261.43  E-value: 1.88e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372   61 EVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTNERTFSRKWKEIFYTKKIER 140
Cdd:TIGR02074   9 DIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEALLALKLEQ 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  141 TFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRNVVLRLMEKE 220
Cdd:TIGR02074  89 KLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNLVLSNMVEN 168
                         170
                  ....*....|....*..
gi 446587372  221 GYISHDEYVQAVSEKLV 237
Cdd:TIGR02074 169 GYITAEEAEEAINEPIQ 185
Transgly pfam00912
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ...
42-218 1.26e-83

Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.


Pssm-ID: 459993 [Multi-domain]  Cd Length: 177  Bit Score: 247.44  E-value: 1.26e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372   42 GNVMIEQSDISKLHVPAKlEVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTN 121
Cdd:pfam00912   2 GTLLAELGEENREYVPLD-DIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  122 ERTFSRKWKEIFYTKKIERTFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQ 201
Cdd:pfam00912  81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
                         170
                  ....*....|....*..
gi 446587372  202 NYDKAVERRNVVLRLME 218
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
mrcA PRK11636
penicillin-binding protein 1a; Provisional
53-240 6.91e-68

penicillin-binding protein 1a; Provisional


Pssm-ID: 183248 [Multi-domain]  Cd Length: 850  Bit Score: 224.62  E-value: 6.91e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  53 KLHVPAKL-EVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTNERTFSRKWKE 131
Cdd:PRK11636  64 KRRIPLTLdQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKE 143
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 132 IFYTKKIERTFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRN 211
Cdd:PRK11636 144 AFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRN 223
                        170       180
                 ....*....|....*....|....*....
gi 446587372 212 VVLRLMEKEGYISHDEYVQAVSEKLVIRH 240
Cdd:PRK11636 224 VVLSRMLDEGYITQAQYDQARSEPIVANY 252
PBP_1b TIGR02071
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ...
61-236 1.18e-57

penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 273952 [Multi-domain]  Cd Length: 730  Bit Score: 195.32  E-value: 1.18e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372   61 EVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTNERTFSRKWKEIFYTKKIER 140
Cdd:TIGR02071 154 QFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDA 233
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  141 TFTKDEILKLYVSNIYYG----EGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRNVVLRL 216
Cdd:TIGR02071 234 RYSKDRILELYLNEVYLGqsgdDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRL 313
                         170       180
                  ....*....|....*....|
gi 446587372  217 MEKEGYISHDEYVQAVSEKL 236
Cdd:TIGR02071 314 LQEQKIIDDEEYDMLSARPL 333
PbpC COG4953
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ...
61-239 7.60e-54

Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443980 [Multi-domain]  Cd Length: 773  Bit Score: 185.42  E-value: 7.60e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  61 EVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLsknAFLT--NERTFSRKWKEIFYTKKI 138
Cdd:COG4953   72 EVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQV---ARLLepRPRTLSGKLRQILRALQL 148
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 139 ERTFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRNVVLRLME 218
Cdd:COG4953  149 ERRYSKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLA 228
                        170       180
                 ....*....|....*....|.
gi 446587372 219 KEGYISHDEYVQAVSEKLVIR 239
Cdd:COG4953  229 EAGVIDAEEAALALLEPVPAR 249
mrcB PRK09506
bifunctional glycosyl transferase/transpeptidase; Reviewed
63-228 7.48e-47

bifunctional glycosyl transferase/transpeptidase; Reviewed


Pssm-ID: 236544 [Multi-domain]  Cd Length: 830  Bit Score: 166.48  E-value: 7.48e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  63 PESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTNERTFSRKWKEIFYTKKIERTF 142
Cdd:PRK09506 220 PDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARY 299
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 143 TKDEILKLYVSNIYYGEGA----WGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRNVVLRLME 218
Cdd:PRK09506 300 SKDRILELYLNEVYLGQSGddqiRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQ 379
                        170
                 ....*....|
gi 446587372 219 KEGYISHDEY 228
Cdd:PRK09506 380 QQQIIDQELY 389
PRK13481 PRK13481
glycosyltransferase; Provisional
62-234 1.66e-46

glycosyltransferase; Provisional


Pssm-ID: 184078 [Multi-domain]  Cd Length: 232  Bit Score: 154.96  E-value: 1.66e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  62 VPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVvQGGSTITQQLSKNAFLTNERTFSRKWKEIFYTKKIERT 141
Cdd:PRK13481  53 MPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDV-QGGSTITQQVVKNYFYDNERSFTRKVKELFVAHRVEKQ 131
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 142 FTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVN-------QLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRNVVL 214
Cdd:PRK13481 132 YSKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNknsttmsHITVLQSAILASKVNAPSVYNINDMSENFTQRVSTNL 211
                        170       180
                 ....*....|....*....|
gi 446587372 215 RLMEKEGYISHDEYVQAVSE 234
Cdd:PRK13481 212 EKMKQQNYINETQYQQAMSQ 231
mono_pep_trsgly TIGR02070
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ...
61-217 4.87e-41

monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]


Pssm-ID: 273951 [Multi-domain]  Cd Length: 224  Bit Score: 140.67  E-value: 4.87e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372   61 EVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTNERTFSRKWKEIFYTKKIER 140
Cdd:TIGR02070  62 QISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWMLET 141
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446587372  141 TFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRNVVLRLM 217
Cdd:TIGR02070 142 WWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWILKQM 218
PRK14850 PRK14850
penicillin-binding protein 1b; Provisional
53-239 1.29e-40

penicillin-binding protein 1b; Provisional


Pssm-ID: 237835 [Multi-domain]  Cd Length: 764  Bit Score: 148.45  E-value: 1.29e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  53 KLHVPAKlEVPESLTHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLSKNAFLTNERTFSRKWKEI 132
Cdd:PRK14850 157 RLFIPRN-QYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKINEI 235
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 133 FYTKKIERTFTKDEILKLYVSNIYYG----EGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVE 208
Cdd:PRK14850 236 YMALILDRFYSKDRILELYLNEVYLGqdgnEQIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTLK 315
                        170       180       190
                 ....*....|....*....|....*....|.
gi 446587372 209 RRNVVLRLMEKEGYISHDEYVQAVSEKLVIR 239
Cdd:PRK14850 316 RRNLVLFLLYKQKVITRKLYKDLCSRPLNVQ 346
PRK11240 PRK11240
penicillin-binding protein 1C; Provisional
63-221 1.90e-25

penicillin-binding protein 1C; Provisional


Pssm-ID: 183049 [Multi-domain]  Cd Length: 772  Bit Score: 104.78  E-value: 1.90e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372  63 PESLtHAFIATEDKRFYHHNGLDYIAIIRASVENIKAGGVVQGGSTITQQLsknAFLTN--ERTFSRKWKEIFYTKKIER 140
Cdd:PRK11240  72 PRYL-EALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQV---ARLLDphPRTFGGKIRQLWRALQLEW 147
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446587372 141 TFTKDEILKLYVSNIYYGEGAWGIEKAANLYFGKKVNQLTLAESAMMAAVVKAPAYYSPAQNYDKAVERRNVVLRLMEKE 220
Cdd:PRK11240 148 HLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLERMAEQ 227

                 .
gi 446587372 221 G 221
Cdd:PRK11240 228 G 228
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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