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MULTISPECIES: aldehyde oxidoreductase molybdenum-binding subunit PaoC [Escherichia]
Protein Classification
xanthine dehydrogenase family protein molybdopterin-binding subunit ( domain architecture ID 11445946 )
xanthine dehydrogenase family protein molybdopterin-binding subunit is part of an oxidase/dehydrogenase complex acting on one or more of a variety of substrates
List of domain hits
Name
Accession
Description
Interval
E-value
peri_hyde_PaoC
NF041671 aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the ...
1-732
0e+00
aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the molybdopterin-cytosine-dinucleotide cofactor-binding subunit of the periplasmic aldehyde oxidoreductase PaoABC. The enzyme is known formally as carboxylate reductase (EC 1.2.99.6).
Pssm-ID: 469553 [Multi-domain]
Cd Length: 735
Bit Score: 1502.84
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 1 MKFD K PAG E NPIDQLKVVG R P H DRIDGPLKTTGTA R YAYE WYEE APNAAYGYIVG S AIAKG CL T AL D TD AA QK APGVLAV 80
Cdd:NF041671 1 MKFD T PAG T NPIDQLKVVG K P T DRIDGPLKTTGTA P YAYE RHDV APNAAYGYIVG A AIAKG RI T SI D LA AA RA APGVLAV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 81 I TA S NAG A LGKG DK NTA R LL A GP T IEHYHQA I A L VVAETFEQARAAA S LV QAH Y R R NK GA YS LA DE K QAVSQ PP E D T --- 157
Cdd:NF041671 81 V TA L NAG K LGKG KF NTA K LL G GP E IEHYHQA V A V VVAETFEQARAAA A LV RVD Y A R EP GA FD LA AA K DSAPL PP G D P ggp 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 158 PD KN VGDF D GAF TS A A VK I DATYTTPDQSH MA MEPHAS M A V W D G N KLTLWTSNQMI D W C R T DLAKTL KV P V ENVR I ISPY 237
Cdd:NF041671 161 PD TR VGDF E GAF AA A P VK L DATYTTPDQSH AM MEPHAS I A A W E G D KLTLWTSNQMI N W G R G DLAKTL GI P K ENVR L ISPY 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 238 IGGGFGGKLFLR S DA L LAAL A ARA VK RPVKV M LPRP T I P NNTTHRPAT L Q HL RIGA DQS GKITAI S HESWSGNLPGG T PE 317
Cdd:NF041671 241 IGGGFGGKLFLR A DA V LAAL G ARA AG RPVKV A LPRP L I F NNTTHRPAT I Q RI RIGA TRD GKITAI A HESWSGNLPGG R PE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 318 TAVQQ SE LLYAGANR H T GL RLA T LDLPEGNAMRAPGEAPGLMALEIA I DE L AEK A G I DPVEFRILNDTQVDP AD P T R R FS 397
Cdd:NF041671 321 TAVQQ TR LLYAGANR M T AM RLA V LDLPEGNAMRAPGEAPGLMALEIA M DE M AEK L G M DPVEFRILNDTQVDP EK P E R P FS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 398 R RQL I ECLRTGA DK FGW KQ RNA T PGQVR D G E WL V G H GVAA G FRNNLL E KSGARV H L EQN G T VTVETDMTDIGTGSYTI L A 477
Cdd:NF041671 401 Q RQL V ECLRTGA ER FGW SR RNA K PGQVR E G R WL I G M GVAA A FRNNLL M KSGARV R L DRD G R VTVETDMTDIGTGSYTI I A 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 478 QTAAEM L GVPL EQ V A V H LGDSSFPVSAGSGGQWGAN T ST S GVYAACVKLRE MI A SAV GF DPGQSQ FADG KITN G T RS AT L 557
Cdd:NF041671 481 QTAAEM M GVPL DR V V V R LGDSSFPVSAGSGGQWGAN S ST A GVYAACVKLRE AV A QRL GF NSADAE FADG QVRA G N RS VP L 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 558 HE A T AGG R L T AE ES IEFG T L S K E YQQSTF AG HFVEVGV HS ATGE V RVRRMLAVCAA V RILNPKTARSQVIGAMTMG M GAA 637
Cdd:NF041671 561 AD A A AGG E L V AE DT IEFG D L A K K YQQSTF GA HFVEVGV DA ATGE T RVRRMLAVCAA G RILNPKTARSQVIGAMTMG V GAA 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 638 LMEELAVD D R L G Y FVNHD M AGYEVPVHADIP K QEVIFLD D TDP I SSPMKAKGVGELGLCGV S AAIANAVYNATG I RVRDY 717
Cdd:NF041671 641 LMEELAVD K R R G F FVNHD L AGYEVPVHADIP H QEVIFLD E TDP V SSPMKAKGVGELGLCGV A AAIANAVYNATG V RVRDY 720
730
....*....|....*
gi 446589706 718 PITLDKLLD K LP D V V 732
Cdd:NF041671 721 PITLDKLLD R LP E V A 735
Name
Accession
Description
Interval
E-value
peri_hyde_PaoC
NF041671 aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the ...
1-732
0e+00
aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the molybdopterin-cytosine-dinucleotide cofactor-binding subunit of the periplasmic aldehyde oxidoreductase PaoABC. The enzyme is known formally as carboxylate reductase (EC 1.2.99.6).
Pssm-ID: 469553 [Multi-domain]
Cd Length: 735
Bit Score: 1502.84
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 1 MKFD K PAG E NPIDQLKVVG R P H DRIDGPLKTTGTA R YAYE WYEE APNAAYGYIVG S AIAKG CL T AL D TD AA QK APGVLAV 80
Cdd:NF041671 1 MKFD T PAG T NPIDQLKVVG K P T DRIDGPLKTTGTA P YAYE RHDV APNAAYGYIVG A AIAKG RI T SI D LA AA RA APGVLAV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 81 I TA S NAG A LGKG DK NTA R LL A GP T IEHYHQA I A L VVAETFEQARAAA S LV QAH Y R R NK GA YS LA DE K QAVSQ PP E D T --- 157
Cdd:NF041671 81 V TA L NAG K LGKG KF NTA K LL G GP E IEHYHQA V A V VVAETFEQARAAA A LV RVD Y A R EP GA FD LA AA K DSAPL PP G D P ggp 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 158 PD KN VGDF D GAF TS A A VK I DATYTTPDQSH MA MEPHAS M A V W D G N KLTLWTSNQMI D W C R T DLAKTL KV P V ENVR I ISPY 237
Cdd:NF041671 161 PD TR VGDF E GAF AA A P VK L DATYTTPDQSH AM MEPHAS I A A W E G D KLTLWTSNQMI N W G R G DLAKTL GI P K ENVR L ISPY 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 238 IGGGFGGKLFLR S DA L LAAL A ARA VK RPVKV M LPRP T I P NNTTHRPAT L Q HL RIGA DQS GKITAI S HESWSGNLPGG T PE 317
Cdd:NF041671 241 IGGGFGGKLFLR A DA V LAAL G ARA AG RPVKV A LPRP L I F NNTTHRPAT I Q RI RIGA TRD GKITAI A HESWSGNLPGG R PE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 318 TAVQQ SE LLYAGANR H T GL RLA T LDLPEGNAMRAPGEAPGLMALEIA I DE L AEK A G I DPVEFRILNDTQVDP AD P T R R FS 397
Cdd:NF041671 321 TAVQQ TR LLYAGANR M T AM RLA V LDLPEGNAMRAPGEAPGLMALEIA M DE M AEK L G M DPVEFRILNDTQVDP EK P E R P FS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 398 R RQL I ECLRTGA DK FGW KQ RNA T PGQVR D G E WL V G H GVAA G FRNNLL E KSGARV H L EQN G T VTVETDMTDIGTGSYTI L A 477
Cdd:NF041671 401 Q RQL V ECLRTGA ER FGW SR RNA K PGQVR E G R WL I G M GVAA A FRNNLL M KSGARV R L DRD G R VTVETDMTDIGTGSYTI I A 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 478 QTAAEM L GVPL EQ V A V H LGDSSFPVSAGSGGQWGAN T ST S GVYAACVKLRE MI A SAV GF DPGQSQ FADG KITN G T RS AT L 557
Cdd:NF041671 481 QTAAEM M GVPL DR V V V R LGDSSFPVSAGSGGQWGAN S ST A GVYAACVKLRE AV A QRL GF NSADAE FADG QVRA G N RS VP L 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 558 HE A T AGG R L T AE ES IEFG T L S K E YQQSTF AG HFVEVGV HS ATGE V RVRRMLAVCAA V RILNPKTARSQVIGAMTMG M GAA 637
Cdd:NF041671 561 AD A A AGG E L V AE DT IEFG D L A K K YQQSTF GA HFVEVGV DA ATGE T RVRRMLAVCAA G RILNPKTARSQVIGAMTMG V GAA 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 638 LMEELAVD D R L G Y FVNHD M AGYEVPVHADIP K QEVIFLD D TDP I SSPMKAKGVGELGLCGV S AAIANAVYNATG I RVRDY 717
Cdd:NF041671 641 LMEELAVD K R R G F FVNHD L AGYEVPVHADIP H QEVIFLD E TDP V SSPMKAKGVGELGLCGV A AAIANAVYNATG V RVRDY 720
730
....*....|....*
gi 446589706 718 PITLDKLLD K LP D V V 732
Cdd:NF041671 721 PITLDKLLD R LP E V A 735
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
10-730
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 685.04
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 10 NPIDQLKVV G R P HD R I DGP L K T TG T ARY AYEW ye EA P NAA Y GYI V G S AI A KGCLTAL DT D AA QKA PGV L AV I T ASNAGA L 89
Cdd:COG1529 2 SDPADFRII G K P VP R V DGP A K V TG R ARY TDDI -- RL P GML Y AAV V R S PH A HARIKSI DT S AA LAL PGV V AV L T GEDLPG L 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 90 GK G DKNTA --- RL LA GPTIEHYHQAI A L VVAET F E Q AR A AA S L VQAH Y RRNKGAYSLADEKQAVSQPPEDTPDK NV ---- 162
Cdd:COG1529 80 KF G LPGPD pdq PP LA DDKVRYVGEPV A A VVAET R E A AR D AA E L IKVE Y EPLPAVVDPEAALAPGAPLVHEELPG NV aaew 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 163 ---- GD F D G AF TS A A V KID ATYTTP DQS H MA MEP H A SM A V WDG N - K LT L W T S N Q MIDWC R TD LA KT L KV P V E N VR I I S P Y 237
Cdd:COG1529 160 rger GD V D A AF AE A D V VVE ATYTTP RLA H AP MEP R A AV A E WDG D g R LT V W A S T Q GPHLV R RA LA RA L GL P P E K VR V I A P D 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 238 I GGGFGGKL FLRSDAL LAALAAR AVK RPVK VM L P R PTIPNNT THR P AT L Q HL R I GAD QS GKITA IS H ESWS ----- GNLP 312
Cdd:COG1529 240 V GGGFGGKL DVYPEEV LAALAAR KLG RPVK LV L T R EEDFLAD THR H AT V Q RV R L GAD KD GKITA LR H DVVA dtgay ASFG 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 313 GGTPETAVQQSELL YA GA N RHTGL R LATLDL P EGN A M R A PG EAPGLM ALE I A I DELAE KA G I DPVE F R IL N DTQVDPAD P 392
Cdd:COG1529 320 EAVLPLGATMATGP YA IP N VRVEA R AVYTNT P PTG A Y R G PG RPQAAF ALE S A M DELAE EL G M DPVE L R LR N LIRPGDFP P 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 393 T - RRFSRRQ L I ECL RTG A DK FGW KQ R N A T P GQV R D G e W L V G H GVAA GFRNN -- LLEKSG ARV H L EQN G T VTV E T DM TDIG 469
Cdd:COG1529 400 T g QPYDSGR L A ECL EKA A EA FGW GE R R A R P AEA R A G - K L R G I GVAA YIEGS gg GGDPES ARV R L NPD G S VTV Y T GA TDIG 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 470 T G SY T I LAQ T AAE M LGVP L E Q V A V H LGD SSF - P VSA G S GG QWGANTST S G V YA A CV KLRE MI ---- A SAV G F DP GQSQ F A 544
Cdd:COG1529 479 Q G HE T V LAQ I AAE E LGVP P E D V R V V LGD TDL t P YGG G T GG SRSTAVGG S A V RK A AE KLRE KL lela A HLL G A DP EDLE F E 558
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 545 DG KITNGT RS AT L H E --- A TAG G R L T A EESIEFG T lske Y QQST F AG H FV EV G V HSA TGEVRV R R ML AV CAAV R IL NP KT 621
Cdd:COG1529 559 DG RVRVPG RS VS L A E laa A AYY G G L E A TGTYDPP T ---- Y PTYS F GA H VA EV E V DPE TGEVRV L R VV AV HDCG R VI NP LL 634
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 622 ARS QV I G AMTM G M G A AL M EEL AV D DR l G YFV N HDM A G Y E VP VH AD I P KQ EVIF LDDT DP i SS P MK AKGVGE L G LC GV SA A 701
Cdd:COG1529 635 VEG QV E G GVVQ G I G Q AL Y EEL VY D ED - G QLL N ANF A D Y L VP RA AD V P EI EVIF VETP DP - TN P LG AKGVGE P G TI GV AP A 712
730 740
....*....|....*....|....*....
gi 446589706 702 IANAVY N ATG I R V RD Y PIT LD K L L DK L PD 730
Cdd:COG1529 713 IANAVY D ATG V R I RD L PIT PE K V L AA L RE 741
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
16-728
5.60e-87
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 290.06
E-value: 5.60e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 16 KVV G RPHD R I D GPL K T TG T A R Y AYEWYE ea PNAA Y GYI V G S A IA K G CLTAL DT DA A QKA PGV L AV I T ----------- A S 84
Cdd:PRK09970 1 MAI G KSIM R V D AIA K V TG R A K Y TDDYVM -- AGML Y AKY V R S P IA H G KVKSI DT EE A RSL PGV E AV F T wedvpdipfpt A G 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 85 NAGA L GKGDKNT A - R L L AGPTIE H YHQ A I A L VVA ETFEQ A RA A AS L VQAH Y RRNKGAYSLADEKQAVSQ P PEDTPDK --- 160
Cdd:PRK09970 79 HPWS L DPNHRDI A d R A L LTRHVR H HGD A V A A VVA RDELT A EK A LK L IKVE Y EELPVITDPEAALAEGAP P IHNGRGN llk 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 161 ---- NV G DFDGAFTS A AVKIDAT Y T TP DQS H MA ME PHA S M A VWDGN - KL T LWT S N Q MIDWC R TDLAKT L KV P VEN VR I I S 235
Cdd:PRK09970 159 qstm ST G NVQQTIKA A DYQVQGH Y E TP IVQ H CH ME NVT S Y A YMEDD g RI T IVS S T Q IPHIV R RVVGQA L GI P WGK VR V I K 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 236 PY I GGGFG G K LFLRSDA L L A A L AARAVK RPVKV M L P R PTIPNN T TH R P A TLQHLRI G ADQS G KITAI S HESW S GN lp G GT 315
Cdd:PRK09970 239 PY V GGGFG N K QDVLEEP L A A F L TSKVGG RPVKV S L S R EECFLA T RT R H A FTIDIKM G VNRD G TLKGY S LDVL S NT -- G AY 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 316 pet A VQQSELLY AG A N RHTG L -------- RLA T L -- D LP EGN AMR AP G e AP GLM - A L E IAI D EL A EKA GIDPVEFR IL N D 384
Cdd:PRK09970 317 --- A SHGHSIAS AG G N KVAY L yprcayky SSK T V yt N LP SAG AMR GY G - AP QVV f A V E SML D DA A TAL GIDPVEFR LR N A 392
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 385 TQVDP A D P T -- R R FSRRQ L I ECL RT G ADK F G W KQ R N A ---- TP G QV R D G ewl VG HGVAAGFRNNL --- LE KS GAR VHLE Q 455
Cdd:PRK09970 393 AREGD A N P L sg K R IYSAG L P ECL EK G RKI F E W DK R R A eckn QQ G NL R R G --- VG VACFSYTSGTW pvg LE IA GAR LLMN Q 469
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 456 N GTV T V ETDM T D IG T GS Y T ILA Q TA AE ML G V P LEQ V A V hlg D S S ----- F P VSA G SGGQWGANTSTSGVYA A CVK L R E M I 530
Cdd:PRK09970 470 D GTV Q V QSGA T E IG Q GS D T VFS Q MV AE TV G I P VSD V R V --- I S T qdtdv T P FDP G AYASRQSYVAGPAIRK A ALE L K E K I 546
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 531 ASAV ---- GFDPGQSQFA DG K I --- TN G TRSAT L H E A -------- TA GG RL TAE E SI EFG T LS keyqq ST F AGH FV E V G V 595
Cdd:PRK09970 547 LAHA avml HQSAMNLDII DG H I vvk RP G EPLMS L E E L amdayyhp ER GG QI TAE S SI KTT T NP ----- PA F GCT FV D V E V 621
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 596 HS A TGE V RVR R M L A V CAAVR ILNP KT A RS QV I G A M T MG M G A AL M EE LAV D DRL G YFV N HDMAG Y EV P VHA D I P KQ E VI F L 675
Cdd:PRK09970 622 DI A LCK V TIN R I L N V HDSGH ILNP LL A EG QV H G G M G MG I G W AL F EE MII D EKT G VVR N PNLLD Y KL P TMM D L P QL E SA F V 701
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 446589706 676 DDTD P i S S PMKA K GV GE LGLCGVSA AI A NAV YN ATG IRVRDY P I T LDK L LDKL 728
Cdd:PRK09970 702 EIYE P - Q S AYGH K SL GE PPIISPAP AI R NAV LM ATG VAINTL P M T PQR L FEEF 753
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
407-668
5.23e-66
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 219.72
E-value: 5.23e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 407 TGADKFGWKQ R N A TPGQVRD G EWLV G H G V A ----- A G FRNNL L EKS GA R V H L EQN G T VTV E T DM T DI G T G SY T I LAQ T AA 481
Cdd:pfam20256 1 KALELSDYDE R R A EQAEFNR G NRKR G I G I A pyveg S G LGPGA L NQA GA L V R L NPD G S VTV Y T GG T EM G Q G LE T K LAQ I AA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 482 E M LG V P L E Q V A V HL GD SSF - P VSA G S G GQWGANTSTSG V YA A CV KLRE MI ---- A SAVGFD P GQSQ F A DGK IT -- NGT RS 554
Cdd:pfam20256 81 E A LG I P P E D V R V VE GD TDT v P NGG G T G ASRSTDVGGNA V LL A AE KLRE RL lkia A HLLEAS P EDLE F E DGK VY vk GDP RS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 555 A T LH E AT A ----- G GR L T A EES ---- IEFGTLSKEYQQSTFAG H FV EV G V HSA TGEVRV R R ML AV CAAV R IL NP KTARS Q 625
Cdd:pfam20256 161 V T FA E LA A aayge G VG L S A TGF ytpp DDETGQGPPFAYYPYGA H AA EV E V DPE TGEVRV L R YV AV HDCG R VI NP AIVEG Q 240
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 446589706 626 VI G AMTM G M G A ALMEEL AV D DR l G YFVNHDMAG Y EV P VH ADIP 668
Cdd:pfam20256 241 IE G GFVQ G I G L ALMEEL VY D ED - G QLLTASLMD Y KI P TA ADIP 282
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
18-725
3.28e-31
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 131.29
E-value: 3.28e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 18 V G R P HDRID G PLKT TG T A R Y A yewy EEA P --- NAAYGYI V G S AI A KGCLTAL D TDA A QKA PGV LAV ITA SN aga L GKGDK 94
Cdd:TIGR02969 576 I G H P IMHLS G VKHA TG E A I Y C ---- DDM P avd QELFLTF V T S SR A HAKIVSI D LSE A LSL PGV VDI ITA EH --- L QDANT 648
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 95 - N T AR LLA GPTIEHYH Q AIAL V V A ETFE QA RA AA SL V QAH YR RNKGAYSLAD E kq A VSQPPEDT P DKNV -- G DF D G AF TS 171
Cdd:TIGR02969 649 f G T EK LLA TDKVHCVG Q LVCA V I A DSEV QA KQ AA KH V KIV YR DLEPLILTIE E -- A IQHKSFFE P ERKL ey G NV D E AF KV 726
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 172 AAVKIDATYTTPD Q S H MA ME PHASMA V WD G -- NKLTLWT S N Q MIDWCRTDL A K TLK V PV EN V RIISPYI GG G FGGK LFLR 249
Cdd:TIGR02969 727 VDQILEGEIHMGG Q E H FY ME TQSMLV V PK G ed QEMDVYV S T Q FPKYIQDIV A A TLK L PV NK V MCHVRRV GG A FGGK VGKT 806
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 250 S DALLAALA A RAVK - R P V KVM L P R PTIPNN T TH R PAT L QHLRI G ADQS G K I T A ISH E SW S G nlp GG TP -------- E TAV 320
Cdd:TIGR02969 807 S IMAAITAF A ANKH g R A V RCT L E R GEDMLI T GG R HPY L GKYKA G FMND G R I V A LDV E HY S N --- GG SS ldeslwvi E MGL 883
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 321 QQSELL Y AGA N - R HT G LRLA T l D LP EGN A M R AP G EAPGLMAL E IA I D E L A E K A G ID P VEF R IL N - DTQV D PADPTRRFSR 398
Cdd:TIGR02969 884 LKMDNA Y KFP N l R CR G WACR T - N LP SNT A F R GF G FPQAGLIT E AC I T E V A A K C G LS P EKV R TI N m YKEI D QTPYKQEINA 962
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 399 RQ L IE C L R TGAD K FGWKQ R NATPGQVRDGEWLVGH G V A ------- A G FRNNLLEKSG A R VH LEQN G T V T V ETDMTDI G T G 471
Cdd:TIGR02969 963 KN L FQ C W R ECMA K SSYSE R KVAVEKFNAENYWKKR G L A viplkfp V G LGSVAMGQAA A L VH IYLD G S V L V THGGIEM G Q G 1042
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 472 SY T ILA Q TAAEM L GV P LEQ va VHL GDS S --- F P VSAG SGG QWG A NTSTSG V YA AC VK L REMIASAVGFD P g Q SQFA D GKI 548
Cdd:TIGR02969 1043 VH T KMI Q VVSRE L KM P MSN -- VHL RGT S tet V P NTNA SGG SVV A DLNGLA V KD AC QT L LKRLEPIISKN P - Q GTWK D WAQ 1119
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 549 T NGTR S AT L hea T A G G RLTAE ES --- I E F G T l SKEYQQSTFAGHFV EV GVHSA TG EVRVR R MLA V CAAVRIL NP KTARS Q 625
Cdd:TIGR02969 1120 T AFDQ S IS L --- S A V G YFRGY ES nin W E K G E - GHPFEYFVYGAACS EV EIDCL TG DHKNI R TDI V MDVGHSI NP ALDIG Q 1195
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 626 V I GA MTM GMG AALM EEL AVDDR l G YFVNHDMAG Y EV P VHA DIP KQ - EVI FL DDTDPISSPMKA KG V GE L G L --- C G V SA A 701
Cdd:TIGR02969 1196 V E GA FIQ GMG LYTI EEL SYSPQ - G ILYSRGPNQ Y KI P AIC DIP TE l HIS FL PPSEHSNTLYSS KG L GE S G V flg C S V FF A 1274
730 740
....*....|....*....|....
gi 446589706 702 I AN AV YN A TGI R VRDY P IT L DKL L 725
Cdd:TIGR02969 1275 I HD AV RA A RQE R GLSG P WK L TSP L 1298
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
32-134
2.75e-23
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 94.89
E-value: 2.75e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 32 TG T ARY AYEW ye EA P NAAYGYI V G S AI A KGCLTAL DT D AA QKA PGV L AV I TA SNAGA L GKGD -- KNTARL LA GPTIEHYH 109
Cdd:smart01008 1 TG E ARY GDDI -- RL P GMLHAAV V R S PV A HARIKSI DT S AA RAM PGV V AV L TA KDVPG L NDFG pl GPDEPV LA DDKVRYVG 78
90 100
....*....|....*....|....*
gi 446589706 110 Q AI A L VVAET F E Q AR A AA SL V QAH Y 134
Cdd:smart01008 79 Q PV A A VVAET E E A AR D AA EA V KVE Y 103
Name
Accession
Description
Interval
E-value
peri_hyde_PaoC
NF041671 aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the ...
1-732
0e+00
aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the molybdopterin-cytosine-dinucleotide cofactor-binding subunit of the periplasmic aldehyde oxidoreductase PaoABC. The enzyme is known formally as carboxylate reductase (EC 1.2.99.6).
Pssm-ID: 469553 [Multi-domain]
Cd Length: 735
Bit Score: 1502.84
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 1 MKFD K PAG E NPIDQLKVVG R P H DRIDGPLKTTGTA R YAYE WYEE APNAAYGYIVG S AIAKG CL T AL D TD AA QK APGVLAV 80
Cdd:NF041671 1 MKFD T PAG T NPIDQLKVVG K P T DRIDGPLKTTGTA P YAYE RHDV APNAAYGYIVG A AIAKG RI T SI D LA AA RA APGVLAV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 81 I TA S NAG A LGKG DK NTA R LL A GP T IEHYHQA I A L VVAETFEQARAAA S LV QAH Y R R NK GA YS LA DE K QAVSQ PP E D T --- 157
Cdd:NF041671 81 V TA L NAG K LGKG KF NTA K LL G GP E IEHYHQA V A V VVAETFEQARAAA A LV RVD Y A R EP GA FD LA AA K DSAPL PP G D P ggp 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 158 PD KN VGDF D GAF TS A A VK I DATYTTPDQSH MA MEPHAS M A V W D G N KLTLWTSNQMI D W C R T DLAKTL KV P V ENVR I ISPY 237
Cdd:NF041671 161 PD TR VGDF E GAF AA A P VK L DATYTTPDQSH AM MEPHAS I A A W E G D KLTLWTSNQMI N W G R G DLAKTL GI P K ENVR L ISPY 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 238 IGGGFGGKLFLR S DA L LAAL A ARA VK RPVKV M LPRP T I P NNTTHRPAT L Q HL RIGA DQS GKITAI S HESWSGNLPGG T PE 317
Cdd:NF041671 241 IGGGFGGKLFLR A DA V LAAL G ARA AG RPVKV A LPRP L I F NNTTHRPAT I Q RI RIGA TRD GKITAI A HESWSGNLPGG R PE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 318 TAVQQ SE LLYAGANR H T GL RLA T LDLPEGNAMRAPGEAPGLMALEIA I DE L AEK A G I DPVEFRILNDTQVDP AD P T R R FS 397
Cdd:NF041671 321 TAVQQ TR LLYAGANR M T AM RLA V LDLPEGNAMRAPGEAPGLMALEIA M DE M AEK L G M DPVEFRILNDTQVDP EK P E R P FS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 398 R RQL I ECLRTGA DK FGW KQ RNA T PGQVR D G E WL V G H GVAA G FRNNLL E KSGARV H L EQN G T VTVETDMTDIGTGSYTI L A 477
Cdd:NF041671 401 Q RQL V ECLRTGA ER FGW SR RNA K PGQVR E G R WL I G M GVAA A FRNNLL M KSGARV R L DRD G R VTVETDMTDIGTGSYTI I A 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 478 QTAAEM L GVPL EQ V A V H LGDSSFPVSAGSGGQWGAN T ST S GVYAACVKLRE MI A SAV GF DPGQSQ FADG KITN G T RS AT L 557
Cdd:NF041671 481 QTAAEM M GVPL DR V V V R LGDSSFPVSAGSGGQWGAN S ST A GVYAACVKLRE AV A QRL GF NSADAE FADG QVRA G N RS VP L 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 558 HE A T AGG R L T AE ES IEFG T L S K E YQQSTF AG HFVEVGV HS ATGE V RVRRMLAVCAA V RILNPKTARSQVIGAMTMG M GAA 637
Cdd:NF041671 561 AD A A AGG E L V AE DT IEFG D L A K K YQQSTF GA HFVEVGV DA ATGE T RVRRMLAVCAA G RILNPKTARSQVIGAMTMG V GAA 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 638 LMEELAVD D R L G Y FVNHD M AGYEVPVHADIP K QEVIFLD D TDP I SSPMKAKGVGELGLCGV S AAIANAVYNATG I RVRDY 717
Cdd:NF041671 641 LMEELAVD K R R G F FVNHD L AGYEVPVHADIP H QEVIFLD E TDP V SSPMKAKGVGELGLCGV A AAIANAVYNATG V RVRDY 720
730
....*....|....*
gi 446589706 718 PITLDKLLD K LP D V V 732
Cdd:NF041671 721 PITLDKLLD R LP E V A 735
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
10-730
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 685.04
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 10 NPIDQLKVV G R P HD R I DGP L K T TG T ARY AYEW ye EA P NAA Y GYI V G S AI A KGCLTAL DT D AA QKA PGV L AV I T ASNAGA L 89
Cdd:COG1529 2 SDPADFRII G K P VP R V DGP A K V TG R ARY TDDI -- RL P GML Y AAV V R S PH A HARIKSI DT S AA LAL PGV V AV L T GEDLPG L 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 90 GK G DKNTA --- RL LA GPTIEHYHQAI A L VVAET F E Q AR A AA S L VQAH Y RRNKGAYSLADEKQAVSQPPEDTPDK NV ---- 162
Cdd:COG1529 80 KF G LPGPD pdq PP LA DDKVRYVGEPV A A VVAET R E A AR D AA E L IKVE Y EPLPAVVDPEAALAPGAPLVHEELPG NV aaew 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 163 ---- GD F D G AF TS A A V KID ATYTTP DQS H MA MEP H A SM A V WDG N - K LT L W T S N Q MIDWC R TD LA KT L KV P V E N VR I I S P Y 237
Cdd:COG1529 160 rger GD V D A AF AE A D V VVE ATYTTP RLA H AP MEP R A AV A E WDG D g R LT V W A S T Q GPHLV R RA LA RA L GL P P E K VR V I A P D 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 238 I GGGFGGKL FLRSDAL LAALAAR AVK RPVK VM L P R PTIPNNT THR P AT L Q HL R I GAD QS GKITA IS H ESWS ----- GNLP 312
Cdd:COG1529 240 V GGGFGGKL DVYPEEV LAALAAR KLG RPVK LV L T R EEDFLAD THR H AT V Q RV R L GAD KD GKITA LR H DVVA dtgay ASFG 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 313 GGTPETAVQQSELL YA GA N RHTGL R LATLDL P EGN A M R A PG EAPGLM ALE I A I DELAE KA G I DPVE F R IL N DTQVDPAD P 392
Cdd:COG1529 320 EAVLPLGATMATGP YA IP N VRVEA R AVYTNT P PTG A Y R G PG RPQAAF ALE S A M DELAE EL G M DPVE L R LR N LIRPGDFP P 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 393 T - RRFSRRQ L I ECL RTG A DK FGW KQ R N A T P GQV R D G e W L V G H GVAA GFRNN -- LLEKSG ARV H L EQN G T VTV E T DM TDIG 469
Cdd:COG1529 400 T g QPYDSGR L A ECL EKA A EA FGW GE R R A R P AEA R A G - K L R G I GVAA YIEGS gg GGDPES ARV R L NPD G S VTV Y T GA TDIG 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 470 T G SY T I LAQ T AAE M LGVP L E Q V A V H LGD SSF - P VSA G S GG QWGANTST S G V YA A CV KLRE MI ---- A SAV G F DP GQSQ F A 544
Cdd:COG1529 479 Q G HE T V LAQ I AAE E LGVP P E D V R V V LGD TDL t P YGG G T GG SRSTAVGG S A V RK A AE KLRE KL lela A HLL G A DP EDLE F E 558
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 545 DG KITNGT RS AT L H E --- A TAG G R L T A EESIEFG T lske Y QQST F AG H FV EV G V HSA TGEVRV R R ML AV CAAV R IL NP KT 621
Cdd:COG1529 559 DG RVRVPG RS VS L A E laa A AYY G G L E A TGTYDPP T ---- Y PTYS F GA H VA EV E V DPE TGEVRV L R VV AV HDCG R VI NP LL 634
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 622 ARS QV I G AMTM G M G A AL M EEL AV D DR l G YFV N HDM A G Y E VP VH AD I P KQ EVIF LDDT DP i SS P MK AKGVGE L G LC GV SA A 701
Cdd:COG1529 635 VEG QV E G GVVQ G I G Q AL Y EEL VY D ED - G QLL N ANF A D Y L VP RA AD V P EI EVIF VETP DP - TN P LG AKGVGE P G TI GV AP A 712
730 740
....*....|....*....|....*....
gi 446589706 702 IANAVY N ATG I R V RD Y PIT LD K L L DK L PD 730
Cdd:COG1529 713 IANAVY D ATG V R I RD L PIT PE K V L AA L RE 741
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
16-728
5.60e-87
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 290.06
E-value: 5.60e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 16 KVV G RPHD R I D GPL K T TG T A R Y AYEWYE ea PNAA Y GYI V G S A IA K G CLTAL DT DA A QKA PGV L AV I T ----------- A S 84
Cdd:PRK09970 1 MAI G KSIM R V D AIA K V TG R A K Y TDDYVM -- AGML Y AKY V R S P IA H G KVKSI DT EE A RSL PGV E AV F T wedvpdipfpt A G 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 85 NAGA L GKGDKNT A - R L L AGPTIE H YHQ A I A L VVA ETFEQ A RA A AS L VQAH Y RRNKGAYSLADEKQAVSQ P PEDTPDK --- 160
Cdd:PRK09970 79 HPWS L DPNHRDI A d R A L LTRHVR H HGD A V A A VVA RDELT A EK A LK L IKVE Y EELPVITDPEAALAEGAP P IHNGRGN llk 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 161 ---- NV G DFDGAFTS A AVKIDAT Y T TP DQS H MA ME PHA S M A VWDGN - KL T LWT S N Q MIDWC R TDLAKT L KV P VEN VR I I S 235
Cdd:PRK09970 159 qstm ST G NVQQTIKA A DYQVQGH Y E TP IVQ H CH ME NVT S Y A YMEDD g RI T IVS S T Q IPHIV R RVVGQA L GI P WGK VR V I K 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 236 PY I GGGFG G K LFLRSDA L L A A L AARAVK RPVKV M L P R PTIPNN T TH R P A TLQHLRI G ADQS G KITAI S HESW S GN lp G GT 315
Cdd:PRK09970 239 PY V GGGFG N K QDVLEEP L A A F L TSKVGG RPVKV S L S R EECFLA T RT R H A FTIDIKM G VNRD G TLKGY S LDVL S NT -- G AY 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 316 pet A VQQSELLY AG A N RHTG L -------- RLA T L -- D LP EGN AMR AP G e AP GLM - A L E IAI D EL A EKA GIDPVEFR IL N D 384
Cdd:PRK09970 317 --- A SHGHSIAS AG G N KVAY L yprcayky SSK T V yt N LP SAG AMR GY G - AP QVV f A V E SML D DA A TAL GIDPVEFR LR N A 392
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 385 TQVDP A D P T -- R R FSRRQ L I ECL RT G ADK F G W KQ R N A ---- TP G QV R D G ewl VG HGVAAGFRNNL --- LE KS GAR VHLE Q 455
Cdd:PRK09970 393 AREGD A N P L sg K R IYSAG L P ECL EK G RKI F E W DK R R A eckn QQ G NL R R G --- VG VACFSYTSGTW pvg LE IA GAR LLMN Q 469
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 456 N GTV T V ETDM T D IG T GS Y T ILA Q TA AE ML G V P LEQ V A V hlg D S S ----- F P VSA G SGGQWGANTSTSGVYA A CVK L R E M I 530
Cdd:PRK09970 470 D GTV Q V QSGA T E IG Q GS D T VFS Q MV AE TV G I P VSD V R V --- I S T qdtdv T P FDP G AYASRQSYVAGPAIRK A ALE L K E K I 546
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 531 ASAV ---- GFDPGQSQFA DG K I --- TN G TRSAT L H E A -------- TA GG RL TAE E SI EFG T LS keyqq ST F AGH FV E V G V 595
Cdd:PRK09970 547 LAHA avml HQSAMNLDII DG H I vvk RP G EPLMS L E E L amdayyhp ER GG QI TAE S SI KTT T NP ----- PA F GCT FV D V E V 621
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 596 HS A TGE V RVR R M L A V CAAVR ILNP KT A RS QV I G A M T MG M G A AL M EE LAV D DRL G YFV N HDMAG Y EV P VHA D I P KQ E VI F L 675
Cdd:PRK09970 622 DI A LCK V TIN R I L N V HDSGH ILNP LL A EG QV H G G M G MG I G W AL F EE MII D EKT G VVR N PNLLD Y KL P TMM D L P QL E SA F V 701
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 446589706 676 DDTD P i S S PMKA K GV GE LGLCGVSA AI A NAV YN ATG IRVRDY P I T LDK L LDKL 728
Cdd:PRK09970 702 EIYE P - Q S AYGH K SL GE PPIISPAP AI R NAV LM ATG VAINTL P M T PQR L FEEF 753
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
407-668
5.23e-66
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 219.72
E-value: 5.23e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 407 TGADKFGWKQ R N A TPGQVRD G EWLV G H G V A ----- A G FRNNL L EKS GA R V H L EQN G T VTV E T DM T DI G T G SY T I LAQ T AA 481
Cdd:pfam20256 1 KALELSDYDE R R A EQAEFNR G NRKR G I G I A pyveg S G LGPGA L NQA GA L V R L NPD G S VTV Y T GG T EM G Q G LE T K LAQ I AA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 482 E M LG V P L E Q V A V HL GD SSF - P VSA G S G GQWGANTSTSG V YA A CV KLRE MI ---- A SAVGFD P GQSQ F A DGK IT -- NGT RS 554
Cdd:pfam20256 81 E A LG I P P E D V R V VE GD TDT v P NGG G T G ASRSTDVGGNA V LL A AE KLRE RL lkia A HLLEAS P EDLE F E DGK VY vk GDP RS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 555 A T LH E AT A ----- G GR L T A EES ---- IEFGTLSKEYQQSTFAG H FV EV G V HSA TGEVRV R R ML AV CAAV R IL NP KTARS Q 625
Cdd:pfam20256 161 V T FA E LA A aayge G VG L S A TGF ytpp DDETGQGPPFAYYPYGA H AA EV E V DPE TGEVRV L R YV AV HDCG R VI NP AIVEG Q 240
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 446589706 626 VI G AMTM G M G A ALMEEL AV D DR l G YFVNHDMAG Y EV P VH ADIP 668
Cdd:pfam20256 241 IE G GFVQ G I G L ALMEEL VY D ED - G QLLTASLMD Y KI P TA ADIP 282
MoCoBD_1
pfam02738 Molybdopterin cofactor-binding domain;
155-383
1.20e-55
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain]
Cd Length: 244
Bit Score: 190.74
E-value: 1.20e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 155 E DT P DKNV ----- GD FDG AF TS A AVKIDAT Y T T PD Q S H MA ME PH A SM AV W D -- GNK LT LWT S N Q MIDWC R TDL A KT L KV P 227
Cdd:pfam02738 3 E EP P NNVA fhrek GD VEA AF AE A DHVVEGE Y R T GR Q E H FY ME TR A AL AV P D de DGR LT VYS S T Q GPHLV R RLV A RV L GI P 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 228 VEN VR I I S P YI GGGFGGK LFLRSDAL LAALAAR AVK RPVK VM L P R PTIPNN T T HR PAT L QHLRI GAD QS GKI T A ISHES - 306
Cdd:pfam02738 83 ENK VR V I V P RV GGGFGGK TQSYPEEA LAALAAR KTG RPVK WV L D R EEDMLA T G HR HPF L IKYKV GAD KD GKI L A LDVDL y 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 307 ---- WSGN L PGGT PE T A VQQSELL Y AGA N RHTGL R LATLDL P EGN A M R AP G EAP G LM ALE IAI DELAE KA G I DP V E F R IL 382
Cdd:pfam02738 163 adgg AYAD L SPAV PE R A LSHLDGP Y KIP N VRVDG R AVYTNT P PNG A F R GF G RPQ G MF ALE RLM DELAE EL G M DP L E L R RR 242
.
gi 446589706 383 N 383
Cdd:pfam02738 243 N 243
PRK09800
PRK09800 putative hypoxanthine oxidase; Provisional
13-728
1.30e-53
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain]
Cd Length: 956
Bit Score: 199.67
E-value: 1.30e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 13 D Q L K V V G RPHDRI D GPLKTTGTAR Y AYEWYEE ap N A AYGYIVG S AI A KGCL T A LD TDA A QKA PGV LA VIT AS N ------- 85
Cdd:PRK09800 167 D D L E V I G KHYPKT D AAKMVQAKPC Y VEDRVTA -- D A CVIKMLR S PH A HALI T H LD VSK A EAL PGV VH VIT HL N cpdiyyt 244
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 86 - A G ALGKGDKNTA R LLA G PTIE H YHQAI A L VVAE TF E Q A RA A AS L VQAH Y RRN K GAY S L a DE KQ A VSQ P ----------- 153
Cdd:PRK09800 245 p G G QSAPEPSPLD R RMF G KKMR H VGDRV A A VVAE SE E I A LE A LK L IDVE Y EVL K PVM S I - DE AM A EDA P vvhdepvvyva 323
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 154 -- P EDTP D K N ------------------------------- V GD F D GA F TS A A V K I DA TY TTPDQSHMAM E P H ASMAVW D 200
Cdd:PRK09800 324 ga P DTLE D D N shaaqrgehmiinfpigsrprkniaasihgh I GD M D KG F AD A D V I I ER TY NSTQAQQCPT E T H ICFTRM D 403
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 201 G NK L TLWT S N Q MIDWC R TDL A KTLKVPVEN V RI I SPYI GGGFG G K -- LF L RS dal LA A L A ARAVK RPV KVMLP R PT - IPN 277
Cdd:PRK09800 404 G DR L VIHA S T Q VPWHL R RQV A RLVGMKQHK V HV I KERV GGGFG S K qd IL L EE --- VC A W A TCVTG RPV LFRYT R EE e FIA 480
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 278 NT THRP A TLQ h LRI GA DQS G KI TA ISHESWSGNL P G G T ----- P ETAVQQ S EL LY AGA N RHTGLRLATLDLPEGN A MRAP 352
Cdd:PRK09800 481 NT SRHV A KVT - VKL GA KKD G RL TA VKMDFRANTG P Y G N hsltv P CNGPAL S LP LY PCD N VDFQVTTYYSNICPNG A YQGY 559
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 353 G EAP G LM A LEI A ID ELAE KAG ID PV E F ---- R ILNDTQVD ---------- P ADPTRRF S R r Q L I E C LR T G ADKFG W KQ rn 418
Cdd:PRK09800 560 G APK G NF A ITM A LA ELAE QLQ ID QL E I iern R VHEGQELK ilgaigegka P TSVPSAA S C - A L E E I LR Q G REMIQ W SS -- 636
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 419 atp GQVRD G E W LV G H GVA A gfrnn LLE KSG -------- ARVH LE QN GT VT V ETDMT DIGTG SY T ILAQT AAE M L GV P LEQ 490
Cdd:PRK09800 637 --- PKPQN G D W HI G R GVA I ----- IMQ KSG ipdidqan CMIK LE SD GT FI V HSGGA DIGTG LD T VVTKL AAE V L HC P PQD 708
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 491 V A V HL GD SSF - PVSA G SGGQW G ANT S TSGVYA A CVK LRE -------- M IASA V G ---- FD PG QSQFAD G KITN G TRS atl 557
Cdd:PRK09800 709 V H V IS GD TDH a LFDK G AYASS G TCF S GNAARL A AEN LRE kilfhgaq M LGEP V A dvql AT PG VVRGKK G EVSF G DIA --- 785
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 558 H EATA G grltaees IE FG T L -- SKE Y QQST FA ---- GH F V EV G V HSA TGE V R VRRML A VCAAVRIL NP KT A RS Q VI GA MT 631
Cdd:PRK09800 786 H KGET G -------- TG FG S L vg TGS Y ITPD FA fpyg AN F A EV A V NTR TGE I R LDKFY A LLDCGTPV NP EL A LG Q IY GA TL 857
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 632 MGM G AALM EE LAV D DR l G YFVNH D MAG Y EV P VHA DIP KQEVIF L DDT D PISS P MK AK GVG E L G LC G VSA AIA N A VYN A T G 711
Cdd:PRK09800 858 RAI G HSMS EE IIY D AE - G HPLTR D LRS Y GA P KIG DIP RDFRAV L VPS D DKVG P FG AK SIS E I G VN G AAP AIA T A IHD A C G 936
810
....*....|....*..
gi 446589706 712 I RV R DYPI T LD K L L DK L 728
Cdd:PRK09800 937 I WL R EWHF T PE K I L TA L 953
PLN02906
PLN02906 xanthine dehydrogenase
12-709
1.08e-33
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain]
Cd Length: 1319
Bit Score: 139.06
E-value: 1.08e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 12 ID Q LKV VG R P HDRIDGP L KT TG T A R YA YE w YEEA PN AAYGYI V G S AIAKGCLTAL D TDA A QKA PG VLAVIT A SNAG algk 91
Cdd:PLN02906 559 VK Q GTA VG Q P EVHLSAE L QV TG E A E YA DD - IPMP PN TLHAAL V L S TKPHARILSI D DSE A KSS PG FAGIFL A KDVP ---- 633
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 92 GD KNTA ------ R L L A GPTIEHYH Q A I AL VVA E T F E Q A R AAA SL V QAH Y RRNKGAY S LADEKQ A V S QP P EDTPDKNV GD F 165
Cdd:PLN02906 634 GD NMIG pvvhde E L F A TDVVTCVG Q V I GV VVA D T Q E N A K AAA RK V KVE Y EELPAIL S IEEAIE A G S FH P NTERRLEK GD V 713
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 166 DGA F T S AAV -- K I DATYTTPD Q S H MAM EP HA S M a VW --- D GN KLTLWT S N Q MIDWCRTDL A KT L KV P VEN V ----- RI -- 233
Cdd:PLN02906 714 ELC F A S GQC dr I I EGEVQMGG Q E H FYL EP NS S L - VW tsd S GN EVHMIS S T Q APQKHQKYV A HV L GL P MSK V vcktk RI gg 792
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 234 ------- I S PY I GGGFGGKLF L rsdallaalaara VK RPVK VM L P R PTIPNN T TH R P A T L QHLRI G ADQS GKI T A ISH E S 306
Cdd:PLN02906 793 gfggket R S AF I AAAAAVPAY L ------------- LN RPVK LT L D R DVDMMI T GQ R H A F L GKYKV G FTNE GKI L A LDL E I 859
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 307 WS -- GN --- L P G GTP E T A VQQ S ELL Y AGA N RHTGLRLATLDL P EGN A M R AP G EAP G LMAL E IA I DEL A EKAGID P V E F R I 381
Cdd:PLN02906 860 YN ng GN sld L S G AVL E R A MFH S DNV Y EIP N VRIVGNVCFTNF P SNT A F R GF G GPQ G MLIT E NW I QRI A VELNKS P E E I R E 939
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 382 L N ----------------------- D TQVDPA D PTR R fsrrqliecl R TGA D K F G ---- WK Q R N -- AT P gqvrdgewl VG 432
Cdd:PLN02906 940 M N fqgegsvthygqvlqhctlpqlw D ELKVSC D FLK R ---------- R EEV D E F N aknr WK K R G va MV P --------- TK 1000
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 433 H G VA ag F RNNLLEKS GA R VH LEQN GTV T V ETDMTDI G T G SY T IL AQ T AA EMLGV PL EQ V AV hl GDS S --- F P VSAGSGGQ 509
Cdd:PLN02906 1001 F G IS -- F TTKFMNQA GA L VH VYTD GTV L V THGGVEM G Q G LH T KV AQ V AA SAFNI PL SS V FI -- SET S tdk V P NASPTAAS 1076
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 510 WGANTSTSG V YA AC VKLREMIA savgfd P GQ S QFADGKITNGTRSATLH -- EAT A G G RLTAEE s I E F --- GTLSKEYQQS 584
Cdd:PLN02906 1077 ASSDMYGAA V LD AC EQIKARME ------ P VA S KLNFSSFAELVTACYFQ ri DLS A H G FYITPD - I G F dwk TGKGNPFNYF 1149
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 585 T FAGH F V EV GVHSA TG EVRV RR MLA V CAAVRIL NP KTARS Q VI GA MTM G M G AALM EEL AVD D ------ R L G YFVNHDMAG 658
Cdd:PLN02906 1150 T YGAA F A EV EIDTL TG DFHT RR VDI V MDLGYSI NP AIDIG Q IE GA FVQ G L G WVAL EEL KWG D aahkwi R P G SLFTCGPGT 1229
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 446589706 659 Y EV P VHA DIP - K QE V IF L DDTDPISSPMKA K G VGE ---- L G l CG V SA AI AN A VYN A 709
Cdd:PLN02906 1230 Y KI P SVN DIP f K FN V SL L KGAPNPKAIHSS K A VGE ppff L A - AS V FF AI KD A IKA A 1284
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
18-725
3.28e-31
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 131.29
E-value: 3.28e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 18 V G R P HDRID G PLKT TG T A R Y A yewy EEA P --- NAAYGYI V G S AI A KGCLTAL D TDA A QKA PGV LAV ITA SN aga L GKGDK 94
Cdd:TIGR02969 576 I G H P IMHLS G VKHA TG E A I Y C ---- DDM P avd QELFLTF V T S SR A HAKIVSI D LSE A LSL PGV VDI ITA EH --- L QDANT 648
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 95 - N T AR LLA GPTIEHYH Q AIAL V V A ETFE QA RA AA SL V QAH YR RNKGAYSLAD E kq A VSQPPEDT P DKNV -- G DF D G AF TS 171
Cdd:TIGR02969 649 f G T EK LLA TDKVHCVG Q LVCA V I A DSEV QA KQ AA KH V KIV YR DLEPLILTIE E -- A IQHKSFFE P ERKL ey G NV D E AF KV 726
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 172 AAVKIDATYTTPD Q S H MA ME PHASMA V WD G -- NKLTLWT S N Q MIDWCRTDL A K TLK V PV EN V RIISPYI GG G FGGK LFLR 249
Cdd:TIGR02969 727 VDQILEGEIHMGG Q E H FY ME TQSMLV V PK G ed QEMDVYV S T Q FPKYIQDIV A A TLK L PV NK V MCHVRRV GG A FGGK VGKT 806
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 250 S DALLAALA A RAVK - R P V KVM L P R PTIPNN T TH R PAT L QHLRI G ADQS G K I T A ISH E SW S G nlp GG TP -------- E TAV 320
Cdd:TIGR02969 807 S IMAAITAF A ANKH g R A V RCT L E R GEDMLI T GG R HPY L GKYKA G FMND G R I V A LDV E HY S N --- GG SS ldeslwvi E MGL 883
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 321 QQSELL Y AGA N - R HT G LRLA T l D LP EGN A M R AP G EAPGLMAL E IA I D E L A E K A G ID P VEF R IL N - DTQV D PADPTRRFSR 398
Cdd:TIGR02969 884 LKMDNA Y KFP N l R CR G WACR T - N LP SNT A F R GF G FPQAGLIT E AC I T E V A A K C G LS P EKV R TI N m YKEI D QTPYKQEINA 962
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 399 RQ L IE C L R TGAD K FGWKQ R NATPGQVRDGEWLVGH G V A ------- A G FRNNLLEKSG A R VH LEQN G T V T V ETDMTDI G T G 471
Cdd:TIGR02969 963 KN L FQ C W R ECMA K SSYSE R KVAVEKFNAENYWKKR G L A viplkfp V G LGSVAMGQAA A L VH IYLD G S V L V THGGIEM G Q G 1042
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 472 SY T ILA Q TAAEM L GV P LEQ va VHL GDS S --- F P VSAG SGG QWG A NTSTSG V YA AC VK L REMIASAVGFD P g Q SQFA D GKI 548
Cdd:TIGR02969 1043 VH T KMI Q VVSRE L KM P MSN -- VHL RGT S tet V P NTNA SGG SVV A DLNGLA V KD AC QT L LKRLEPIISKN P - Q GTWK D WAQ 1119
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 549 T NGTR S AT L hea T A G G RLTAE ES --- I E F G T l SKEYQQSTFAGHFV EV GVHSA TG EVRVR R MLA V CAAVRIL NP KTARS Q 625
Cdd:TIGR02969 1120 T AFDQ S IS L --- S A V G YFRGY ES nin W E K G E - GHPFEYFVYGAACS EV EIDCL TG DHKNI R TDI V MDVGHSI NP ALDIG Q 1195
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 626 V I GA MTM GMG AALM EEL AVDDR l G YFVNHDMAG Y EV P VHA DIP KQ - EVI FL DDTDPISSPMKA KG V GE L G L --- C G V SA A 701
Cdd:TIGR02969 1196 V E GA FIQ GMG LYTI EEL SYSPQ - G ILYSRGPNQ Y KI P AIC DIP TE l HIS FL PPSEHSNTLYSS KG L GE S G V flg C S V FF A 1274
730 740
....*....|....*....|....
gi 446589706 702 I AN AV YN A TGI R VRDY P IT L DKL L 725
Cdd:TIGR02969 1275 I HD AV RA A RQE R GLSG P WK L TSP L 1298
Ald_Xan_dh_C
pfam01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
34-138
3.03e-30
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain]
Cd Length: 107
Bit Score: 115.02
E-value: 3.03e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 34 T ARYA Y EWYEE AP NAA YG YI V G S A IA KGCLTAL DT D AA QKA PGV L AVITA SNAGALGKGDKNTA -- R L L A GPTIE H YH Q A 111
Cdd:pfam01315 1 T GEAV Y VDDIP AP GNL YG AF V R S T IA HAKIVSI DT S AA LAL PGV V AVITA KDLPGGNYNIGPIP ld P L F A TDKVR H VG Q P 80
90 100
....*....|....*....|....*..
gi 446589706 112 IA L VVA ETF E Q AR A AA S LV QAH Y RRNK 138
Cdd:pfam01315 81 IA A VVA DDE E T AR R AA K LV KVE Y EELP 107
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
32-134
2.75e-23
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 94.89
E-value: 2.75e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 32 TG T ARY AYEW ye EA P NAAYGYI V G S AI A KGCLTAL DT D AA QKA PGV L AV I TA SNAGA L GKGD -- KNTARL LA GPTIEHYH 109
Cdd:smart01008 1 TG E ARY GDDI -- RL P GMLHAAV V R S PV A HARIKSI DT S AA RAM PGV V AV L TA KDVPG L NDFG pl GPDEPV LA DDKVRYVG 78
90 100
....*....|....*....|....*
gi 446589706 110 Q AI A L VVAET F E Q AR A AA SL V QAH Y 134
Cdd:smart01008 79 Q PV A A VVAET E E A AR D AA EA V KVE Y 103
PLN00192
PLN00192 aldehyde oxidase
76-670
6.25e-18
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain]
Cd Length: 1344
Bit Score: 89.00
E-value: 6.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 76 GVLAVIT ASN aga LG KG DK N -------- TAR L L A GPTIEHYH Q A IALVVA E T FEQ A RA AA S L VQAH Y R - R N KGAYS L AD E 146
Cdd:PLN00192 636 GVLAVIT FKD --- IP KG GQ N igsktifg PEP L F A DEVTRCAG Q R IALVVA D T QKH A DM AA N L AVVE Y D t E N LEPPI L TV E 712
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 147 k Q AV SQ ------ PP EDT P d K N VGD FDGAFTS A AV KI - D A TYTTPD Q SHMA ME PHASM A VW D - G N KLTLWT S N Q MIDWCRT 218
Cdd:PLN00192 713 - D AV KR sslfev PP FLY P - K P VGD ISKGMAE A DH KI l S A EIKLGS Q YYFY ME TQTAL A LP D e D N CIVVYS S T Q CPEYVHS 790
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 219 DL A KT L KV P VE NVR I I SPYI GGGFGGK L f LR S DALLA A L A AR A V K -- RPV KVM L P R P T -- I PNNTT H r P ATLQH l RI G AD 294
Cdd:PLN00192 791 VI A RC L GI P EH NVR V I TRRV GGGFGGK A - VK S MPVAT A C A LA A F K lq RPV RMY L N R K T dm I MAGGR H - P MKITY - SV G FK 867
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 295 QS GKITA I --------- SHESW S GNL P ggtpe TAVQQSELL Y AGANRHTGLRLATLD L PEGN AMRAPGE AP G LMAL E IA I 365
Cdd:PLN00192 868 SD GKITA L hldilinag ISPDI S PIM P ----- RNIIGALKK Y DWGALSFDIKVCKTN L SSRS AMRAPGE VQ G SYIA E AI I 942
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 366 DEL A EKAGI D PVEF R IL N dtq VDPADPTRR F SRRQLI E C ---- L RTGA DK F ---- GW KQR NATPGQV - R DGE W L ------ 430
Cdd:PLN00192 943 EHV A STLSM D VDSV R KI N --- LHTYESLKL F YGDSAG E P seyt L PSIW DK L asss EF KQR TEMVKEF n R SNK W K krgisr 1019
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 431 -- VG H G V aagfrnn L L EKSGAR V HLEQN G TVT VE TDMTD IG T G SY T ILA Q T AA EM LG -------- VP L EQVA V HLG D SSF 500
Cdd:PLN00192 1020 vp IV H E V ------- M L RPTPGK V SILSD G SIA VE VGGIE IG Q G LW T KVK Q M AA FG LG mikcdgge DL L DKIR V IQS D TLS 1092
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 501 PVSA G - SG G QWGANT S TSG V YAA CV K L R E MIA savgfd P GQSQF a DGKITNG T RSATLHE A TAGG - R L T A EESIEFGTL S 578
Cdd:PLN00192 1093 MIQG G f TA G STTSES S CEA V RLC CV I L V E RLK ------ P IKERL - QEQMGSV T WDMLISQ A YMQS v N L S A SSYYTPDPS S 1165
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589706 579 K EY QQSTF A GHF VEV GV hs A TGE VRVR R MLAVCAAVRI LNP KTARS Q VI GA MTM G M G AALM EE LAVDDR l G YF V NHDMAG 658
Cdd:PLN00192 1166 M EY LNYGA A VSE VEV DL -- L TGE TTIL R SDIIYDCGQS LNP AVDLG Q IE GA FVQ G I G FFML EE YTTNSD - G LV V TDGTWT 1242
650
....*....|..
gi 446589706 659 Y EV P VHAD IPKQ 670
Cdd:PLN00192 1243 Y KI P TVDT IPKQ 1254
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
