|
Name |
Accession |
Description |
Interval |
E-value |
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-850 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 1927.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 1 MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQVYSADGELIAQYGEKRRIPVTLDQIPPEMIN 80
Cdd:PRK11636 1 MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 81 AFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEIL 160
Cdd:PRK11636 81 AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNVVLSRMLSEGYITQAQY 240
Cdd:PRK11636 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 241 DQARSEPIDANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA 320
Cdd:PRK11636 241 DQARSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 321 NVLWKVGETAWDSKKITDTLKALPTYGPLLPAVVTSANPQEATAALADGTSVSLHMEGMRWARPYRSDTQQGPTPRKVTD 400
Cdd:PRK11636 321 NVLWKVGESAWDNKKITDTLKALPTYGPLLPAVVTSANPQEATAMLADGSSVALPMEGVRWARPYRSDTQQGPTPRKVTD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 401 VVQTGQQIWVRQVDNDWWLAQVPEVNSALVSLNPQTGAVLALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL 480
Cdd:PRK11636 401 VVQTGQQIWVRQVDDAWWLAQVPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 481 TLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES 560
Cdd:PRK11636 481 TLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 561 LALGSASFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKIACPECDIPVIYGNTQKSDVLENTNVEEVAV 640
Cdd:PRK11636 561 LALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKVACPECDIPVIYGDTQKSNVLENDDVENVAT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 641 SQEQQNSAVPMPELEQANQALVAQNGTQEYAPHVINTPLAFLIKSALNTNIFGEPGWMGTGWRAARDLKRRDIGGKTGTT 720
Cdd:PRK11636 641 SQEQQNSSVPMPQLEQANQALVAQNGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWMGTGWRAGRDLKRRDIGGKTGTT 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 721 NSSKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPGIV 800
Cdd:PRK11636 721 NSSKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTASGAIKDQISGYEGGAKSAQPAWDDYMKAALEGVPEQPLTPPPGIV 800
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 446596466 801 TVNIDRSTGQLASGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGETHELF 850
Cdd:PRK11636 801 TVNIDRSTGKLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGETHELF 850
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-850 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 1235.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 1 MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQVYSADGELIAQYGEKRRIPVTLDQIPPEMIN 80
Cdd:COG5009 1 MRLLKILLILLLLLLLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLIN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 81 AFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEIL 160
Cdd:COG5009 81 AFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNVVLSRMLSEGYITQAQY 240
Cdd:COG5009 161 ELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 241 DQARSEPIDANYHAPEIAFSAPYLSEMVRQEMYNRYGE-SAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGP 319
Cdd:COG5009 241 EAAKAEPLTARYHGASAEVDAPYFAEMVRRELVERYGEdALYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDRRHGYRGP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 320 ANVLWkVGETAWDskkitDTLKALPTYGPLLPAVVTSANPQEATAALADGTSVSLHMEGMRWARPYRSDTQQGPTPRKVT 399
Cdd:COG5009 321 EAHLD-LAEEDWD-----EALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGTLPLEGLKWARPYINDNRRGPAPKSAS 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 400 DVVQTGQQIWVRQV-DNDWWLAQVPEVNSALVSLNPQTGAVLALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDK 478
Cdd:COG5009 395 DVLKPGDVIRVRPVaDGGWRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFVYAAALDN 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 479 GLTLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQnIVHT 558
Cdd:COG5009 475 GYTPATIINDAPIVFDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYSK-LPPN 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 559 ESLALGSASFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKIACPECDipviygntqksdvlentnveev 638
Cdd:COG5009 554 LSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARACEDCD---------------------- 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 639 avsqeQQNSAVPMPELeqanqalvaqngtQEYAPHVINTPLAFLIKSALNTNIfgepgWMGTGWRAaRDLKRrDIGGKTG 718
Cdd:COG5009 612 -----AAEWDGAEPRL-------------PDPAEQVIDPRTAYQMTSMLRGVV-----QRGTGRRA-RALGR-DIAGKTG 666
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 719 TTNSSKDAWFSGYGPGVVTSVWIGFDDHRRdLGRttasgaikdqisgYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG 798
Cdd:COG5009 667 TTNDSKDAWFVGFTPDLVAGVWVGFDDPRS-LGR-------------GETGGRAALPIWIDFMKAALKDKPEKPFPVPEG 732
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 446596466 799 IVTVNIDRSTGQLASGG--NSREEYFIEGTQPTQQAVHEVGTTiIDNGETHELF 850
Cdd:COG5009 733 IVTVRIDPKTGLLASPGdpDAIFEAFKPGTEPTESASEDLGPD-ASEGTGEGLF 785
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
65-787 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 581.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 65 RRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEA 144
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 145 FLAIRIEQLLNKNEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNV 224
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 225 VLSRMLSEGYITQAQYDQARSEPIDANYHAP-EIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAV 303
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKkSEQYKAPYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAAEKVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 304 RNNVLDYDMRHGYrgpanvlwkvgetawdskkitdtlkalptygpllpavvtsanpqeataaladgtsvslhmegmrwar 383
Cdd:TIGR02074 241 NTGLRVAGRRDGD------------------------------------------------------------------- 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 384 pyrsdtqqgptprkvtdvvqtgqqiwvrqvdndwwlaqvpEVNSALVSLNPQTGAVLALVGGFDFNQSKFNRATQALRQV 463
Cdd:TIGR02074 254 ----------------------------------------DLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQP 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 464 GSNIKPFLYTAAMDKGLTLASMLNDVPISrwdAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAE 543
Cdd:TIGR02074 294 GSTFKPFVYAAALEKGLTPATIVNDEPIT---YNGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVA 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 544 YLQRFGFPAqNIVHTESLALGSASFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKiacpecdipviygn 623
Cdd:TIGR02074 371 LAKRFGITS-PLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPK-------------- 435
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 624 tqksdvlentnvEEVAVSQEQQNSAVPMpeleqanqalvaqngtqeyaphvintplaflIKSALNtnifgepgwMGTGWR 703
Cdd:TIGR02074 436 ------------TTQVISPATAYIMTDM-------------------------------LKGVVE---------SGTGRS 463
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 704 AArdLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDhRRDLGRTTasgaikdqisgyeGGAKSAQPAWDAYMKA 783
Cdd:TIGR02074 464 AR--LPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDD-KKTLGKSG-------------TGGGLAAPIWRDFMAE 527
|
....
gi 446596466 784 VLEG 787
Cdd:TIGR02074 528 ALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
54-230 |
2.41e-91 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 285.18 E-value: 2.41e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 54 DGELIAQYGEKRRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSP 133
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 134 ERTLMRKIKEAFLAIRIEQLLNKNEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLY 213
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 446596466 214 SMDRAIARRNVVLSRML 230
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-850 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 1927.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 1 MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQVYSADGELIAQYGEKRRIPVTLDQIPPEMIN 80
Cdd:PRK11636 1 MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 81 AFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEIL 160
Cdd:PRK11636 81 AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNVVLSRMLSEGYITQAQY 240
Cdd:PRK11636 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 241 DQARSEPIDANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA 320
Cdd:PRK11636 241 DQARSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 321 NVLWKVGETAWDSKKITDTLKALPTYGPLLPAVVTSANPQEATAALADGTSVSLHMEGMRWARPYRSDTQQGPTPRKVTD 400
Cdd:PRK11636 321 NVLWKVGESAWDNKKITDTLKALPTYGPLLPAVVTSANPQEATAMLADGSSVALPMEGVRWARPYRSDTQQGPTPRKVTD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 401 VVQTGQQIWVRQVDNDWWLAQVPEVNSALVSLNPQTGAVLALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL 480
Cdd:PRK11636 401 VVQTGQQIWVRQVDDAWWLAQVPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 481 TLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES 560
Cdd:PRK11636 481 TLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 561 LALGSASFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKIACPECDIPVIYGNTQKSDVLENTNVEEVAV 640
Cdd:PRK11636 561 LALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKVACPECDIPVIYGDTQKSNVLENDDVENVAT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 641 SQEQQNSAVPMPELEQANQALVAQNGTQEYAPHVINTPLAFLIKSALNTNIFGEPGWMGTGWRAARDLKRRDIGGKTGTT 720
Cdd:PRK11636 641 SQEQQNSSVPMPQLEQANQALVAQNGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWMGTGWRAGRDLKRRDIGGKTGTT 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 721 NSSKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPGIV 800
Cdd:PRK11636 721 NSSKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTASGAIKDQISGYEGGAKSAQPAWDDYMKAALEGVPEQPLTPPPGIV 800
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 446596466 801 TVNIDRSTGQLASGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGETHELF 850
Cdd:PRK11636 801 TVNIDRSTGKLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGETHELF 850
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-850 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 1235.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 1 MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQVYSADGELIAQYGEKRRIPVTLDQIPPEMIN 80
Cdd:COG5009 1 MRLLKILLILLLLLLLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLIN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 81 AFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEIL 160
Cdd:COG5009 81 AFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNVVLSRMLSEGYITQAQY 240
Cdd:COG5009 161 ELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 241 DQARSEPIDANYHAPEIAFSAPYLSEMVRQEMYNRYGE-SAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGP 319
Cdd:COG5009 241 EAAKAEPLTARYHGASAEVDAPYFAEMVRRELVERYGEdALYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDRRHGYRGP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 320 ANVLWkVGETAWDskkitDTLKALPTYGPLLPAVVTSANPQEATAALADGTSVSLHMEGMRWARPYRSDTQQGPTPRKVT 399
Cdd:COG5009 321 EAHLD-LAEEDWD-----EALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGTLPLEGLKWARPYINDNRRGPAPKSAS 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 400 DVVQTGQQIWVRQV-DNDWWLAQVPEVNSALVSLNPQTGAVLALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDK 478
Cdd:COG5009 395 DVLKPGDVIRVRPVaDGGWRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFVYAAALDN 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 479 GLTLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQnIVHT 558
Cdd:COG5009 475 GYTPATIINDAPIVFDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYSK-LPPN 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 559 ESLALGSASFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKIACPECDipviygntqksdvlentnveev 638
Cdd:COG5009 554 LSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARACEDCD---------------------- 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 639 avsqeQQNSAVPMPELeqanqalvaqngtQEYAPHVINTPLAFLIKSALNTNIfgepgWMGTGWRAaRDLKRrDIGGKTG 718
Cdd:COG5009 612 -----AAEWDGAEPRL-------------PDPAEQVIDPRTAYQMTSMLRGVV-----QRGTGRRA-RALGR-DIAGKTG 666
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 719 TTNSSKDAWFSGYGPGVVTSVWIGFDDHRRdLGRttasgaikdqisgYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG 798
Cdd:COG5009 667 TTNDSKDAWFVGFTPDLVAGVWVGFDDPRS-LGR-------------GETGGRAALPIWIDFMKAALKDKPEKPFPVPEG 732
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 446596466 799 IVTVNIDRSTGQLASGG--NSREEYFIEGTQPTQQAVHEVGTTiIDNGETHELF 850
Cdd:COG5009 733 IVTVRIDPKTGLLASPGdpDAIFEAFKPGTEPTESASEDLGPD-ASEGTGEGLF 785
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-832 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 647.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 1 MKFVKYLLILAVCCILLGAGSIYGLYRYIEpqLPDVATLKDVRLQIPMQVYSADGELIAQYGEKRRIPVTLDQIPPEMIN 80
Cdd:COG0744 11 LRRLLGLLLLLLAVLVLAALAGLVALYVAD--LPDPEELEDLALPQTSTIYDRDGTLIATLGDENREWVPLDQIPPHLKD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 81 AFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEIL 160
Cdd:COG0744 89 AVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEIL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 161 ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNVVLSRMLSEGYITQAQY 240
Cdd:COG0744 169 ELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 241 DQARSEPID-ANYHAPEIAFSAPYLSEMVRQEMYNRYGESA-YEDGYRIYTTITRKVQQAAQQAVRNNVldydmrhgyrg 318
Cdd:COG0744 249 DAAKAEPLTlVPPPNGAAAGKYPYFVDYVRRELEELLGEDDlYRGGLKIYTTLDPKLQKAAEKAVKNVL----------- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 319 panvlwkvgetawdskkitdtlkalptygpllpavvtsanpqeataaladgtsvslhmegmrwarpyrsdtqqgptPRKV 398
Cdd:COG0744 318 ----------------------------------------------------------------------------PEGK 321
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 399 TDVVQTgqqiwvrqvdndwwlaqvpevnsALVSLNPQTGAVLALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDK 478
Cdd:COG0744 322 PGGLQA-----------------------ALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEQ 378
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 479 GLTLASMLNDVPISrwdaGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPaQNIVHT 558
Cdd:COG0744 379 GYTPATTVDDEPVT----FPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPN 453
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 559 ESLALGSASFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKiacpecdipviygntqksdvlentnveev 638
Cdd:COG0744 454 PSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPK----------------------------- 504
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 639 avsqeqqnsavpmpeleqanqalvaqnGTQEYAPHVintplAFLIKSALNTNIFGepgwmGTGWRAArdLKRRDIGGKTG 718
Cdd:COG0744 505 ---------------------------CEQVISPEV-----AYLMTDMLQDVVTS-----GTGRAAR--LPGRPVAGKTG 545
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 719 TTNSSKDAWFSGYGPGVVTSVWIGFDDhrrdlGRTTasgaikdqisGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG 798
Cdd:COG0744 546 TTNDNRDAWFVGYTPQLVTAVWVGNDD-----NSPM----------GYVTGGSLPAPIWRDFMEAALEGLPVEDFPKPSG 610
|
810 820 830
....*....|....*....|....*....|....
gi 446596466 799 IVTVNIDRSTGQlasggnsreeyfieGTQPTQQA 832
Cdd:COG0744 611 VVRIDEPSPTPS--------------GTEPTETS 630
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
65-787 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 581.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 65 RRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEA 144
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 145 FLAIRIEQLLNKNEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNV 224
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 225 VLSRMLSEGYITQAQYDQARSEPIDANYHAP-EIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAV 303
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKkSEQYKAPYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAAEKVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 304 RNNVLDYDMRHGYrgpanvlwkvgetawdskkitdtlkalptygpllpavvtsanpqeataaladgtsvslhmegmrwar 383
Cdd:TIGR02074 241 NTGLRVAGRRDGD------------------------------------------------------------------- 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 384 pyrsdtqqgptprkvtdvvqtgqqiwvrqvdndwwlaqvpEVNSALVSLNPQTGAVLALVGGFDFNQSKFNRATQALRQV 463
Cdd:TIGR02074 254 ----------------------------------------DLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQP 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 464 GSNIKPFLYTAAMDKGLTLASMLNDVPISrwdAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAE 543
Cdd:TIGR02074 294 GSTFKPFVYAAALEKGLTPATIVNDEPIT---YNGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVA 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 544 YLQRFGFPAqNIVHTESLALGSASFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKiacpecdipviygn 623
Cdd:TIGR02074 371 LAKRFGITS-PLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPK-------------- 435
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 624 tqksdvlentnvEEVAVSQEQQNSAVPMpeleqanqalvaqngtqeyaphvintplaflIKSALNtnifgepgwMGTGWR 703
Cdd:TIGR02074 436 ------------TTQVISPATAYIMTDM-------------------------------LKGVVE---------SGTGRS 463
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 704 AArdLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDhRRDLGRTTasgaikdqisgyeGGAKSAQPAWDAYMKA 783
Cdd:TIGR02074 464 AR--LPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDD-KKTLGKSG-------------TGGGLAAPIWRDFMAE 527
|
....
gi 446596466 784 VLEG 787
Cdd:TIGR02074 528 ALKN 531
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
36-830 |
6.69e-112 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 358.65 E-value: 6.69e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 36 VATLKDVRLQIPMQVYSADGELIA----QYGEKRRIpVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALFS 111
Cdd:TIGR02071 114 LSKIENLDNNKEFGFFRLDPKLIAmlysPNGEQRLF-VPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTA 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 112 GHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEILELYLNKIYLGYRA----YGVGAAAQVYFGKT 187
Cdd:TIGR02071 193 GRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKDRILELYLNEVYLGQSGddaiHGFPLASQYYFGRP 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 188 VDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNVVLSRMLSEGYITQAQYDQARSEPIDANyHAPEIAFSAPYLSEM 267
Cdd:TIGR02071 273 LGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQKIIDDEEYDMLSARPLGVQ-KKGGIISRQPAFLQL 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 268 VRQEMYNRYGESAYED-GYRIYTTITRKVQQAAQQAVRnnvldydmrhgyrgpanvlwkvgetawdskkitDTLKALpty 346
Cdd:TIGR02071 352 VRRELRQKLGDKVKDLsGLRIFTTLDPVSQSAAEQAVQ---------------------------------ETIPAL--- 395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 347 gpllpavvtsanpqeataaladgtsvslhmegmrwarpyrsdtqqgptpRKVTdvvqtgqqiwvrqvdndwwlaQVPEVN 426
Cdd:TIGR02071 396 -------------------------------------------------KKKK---------------------KLPDLE 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 427 SALVSLNPQTGAVLALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMD--KGLTLASMLNDVPISRWDAGaGSDWRP 504
Cdd:TIGR02071 406 AAMVVTDRFTGEVRAMVGGSDPQFAGFNRALQARRQIGSLVKPAVYLTALSqpDKYRLNTWIEDQPLSIKLSN-GQVWSP 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 505 KNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGG 584
Cdd:TIGR02071 485 QNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINKDEIPPVPSMLLGAINLTPYEVAQLYQTIASGG 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 585 FLIDPYFISKIENDQGGVLFEAKPkiacpecdipviygntqksdvlentnveevavsqeqqnSAVPMPELEQANQALVA- 663
Cdd:TIGR02071 565 NRAPLSAVRSVLDEDGKVLYQSDP--------------------------------------QAEQAVPSQAAYLTLYAm 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 664 QNGTQEyaphvintplafliksalntnifgepgwmGTGWRAARDLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGF 743
Cdd:TIGR02071 607 QQVVQR-----------------------------GTARSLGADFPSLSLAGKTGTTNDNRDSWFAGIDGKEVTIIWLGR 657
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 744 DDHRRDlGRTTASGAIkdQIsgyeggaksaqpaWDAYMKavlEGVPEQ-PLTPPPGIVTVNIDRSTGQL--ASGGNSREE 820
Cdd:TIGR02071 658 DDNGPT-KLTGASGAL--QV-------------YARYLS---YQTPEPlLLVPPEGIDWFGVDPQGNGGckANCPGARRL 718
|
810
....*....|
gi 446596466 821 YFIEGTQPTQ 830
Cdd:TIGR02071 719 PIWTGNPQAL 728
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
5-830 |
1.98e-105 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 342.58 E-value: 1.98e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 5 KYLLILAVCCILLGAGsIYGLYRYIEPQL---PDVATLkdvrlqipmqVYSADGELIAQY---GEKRRIPVTLDQIPPEM 78
Cdd:COG4953 9 RRLLALLLALLLLALA-LWALDRLFPLPLlfaVPYSTV----------VLDRDGTLLRAFlaaDGQWRLPVPLDEVSPRY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 79 INAFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARnffLS--PERTLMRKIKEAFLAIRIEQLLNK 156
Cdd:COG4953 78 LQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVAR---LLepRPRTLSGKLRQILRALQLERRYSK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 157 NEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNVVLSRMLSEGYIT 236
Cdd:COG4953 155 DEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVID 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 237 QAQYDQARSEPIDANYHAPeiAFSAPYLSEMVRQEmynrygesaYEDGYRIYTTITRKVQQAAQQAVRNnvldydmrhgy 316
Cdd:COG4953 235 AEEAALALLEPVPARRRPL--PQLAPHLARRLLRQ---------LPGGTRIRTTLDAGLQRRLERLVRR----------- 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 317 rgpanvlwkvgetawdskkitdtlkalptygpllpavvtsanpqeataaladgtsvslhmegmrwarpyrsdtqqgptpr 396
Cdd:COG4953 --------------------------------------------------------------------------------
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 397 kvtdvvqtgqqiWVRQvdndwwLAQVPEVNSALVSLNPQTGAVLALVGGFDFN---QSKFNRATQALRQVGSNIKPFLYT 473
Cdd:COG4953 293 ------------YVRR------LKQNGIHNAAVLVVDNRTGEVLAYVGSADFFdasRQGQVDMVRALRSPGSTLKPFLYG 354
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 474 AAMDKGLTL-ASMLNDVPISRwdagagSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPA 552
Cdd:COG4953 355 LALDQGLIHpETLLADVPTSF------GGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRL 428
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 553 QNIVHTE---SLALGSASFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAkpkiacpecdiPVIYgntQKSDV 629
Cdd:COG4953 429 LLPPAEHyglSLILGGAEVTLEELVGLYAALARGGEARPLRLLAGEPASPGRRLLSP-----------GAAW---LVRDI 494
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 630 LentnveevavsqeqqnSAVPMPELEQANQALVAQNgtqeyaphvintPLAFliksalntnifgepgwmgtgwraardlk 709
Cdd:COG4953 495 L----------------SDVPRPDGAFGWRALDSPP------------PIAW---------------------------- 518
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 710 rrdiggKTGTTNSSKDAWFSGYGPGVVTSVWIG-FDdhrrdlGrTTASGAIkdqisgyegGAKSAQPAWDAYMKAVLEGV 788
Cdd:COG4953 519 ------KTGTSYGFRDAWAVGFTGRYTVGVWVGnPD------G-TPVPGLT---------GAEAAAPLLFDIFDLLPASR 576
|
810 820 830 840
....*....|....*....|....*....|....*....|....
gi 446596466 789 PEQPLTPPPGIVTVNIDRSTGQLASG--GNSREEYFIEGTQPTQ 830
Cdd:COG4953 577 WPLPFPPPAGLLRVEVCAPSGLLAGPncPQRVTEWFIPGTSPPT 620
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
54-230 |
2.41e-91 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 285.18 E-value: 2.41e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 54 DGELIAQYGEKRRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSP 133
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 134 ERTLMRKIKEAFLAIRIEQLLNKNEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLY 213
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 446596466 214 SMDRAIARRNVVLSRML 230
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
50-843 |
6.69e-77 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 264.67 E-value: 6.69e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 50 VYSADGELIAQY---GEKRRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLA 126
Cdd:TIGR02073 14 VLDRHGTLLRALlanDGQWRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRRVSGGSTLTMQLA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 127 RNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAP 206
Cdd:TIGR02073 94 RLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALPQAP 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 207 STFNPLYSMDRAIARRNVVLSRMLSEGYITQAQYDQARSEPI-DANYHAPEIafsAPYLSEMVRQEmynrygesAYEDGY 285
Cdd:TIGR02073 174 SARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLpALPEPLPQL---APHFALKLLRA--------RPEIAS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 286 RIYTTITRKVQQAAQQAVRNNvldydmrhgyrgpanvlwkvgetawdskkitdtLKALPtygpllpavvtsanpqeataa 365
Cdd:TIGR02073 243 VIVSTLDADLQRRLEELARRY---------------------------------LSALR--------------------- 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 366 ladgtsvslhmegmrwarpyrsdtqqgptPRKVtdvvqtgqqiwvrqvdndwwlaqvpeVNSALVSLNPQTGAVLALVGG 445
Cdd:TIGR02073 269 -----------------------------PRGI--------------------------SNLAILVVDNRSGAVLAYVGS 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 446 FDFNQ-SKFNR--ATQALRQVGSNIKPFLYTAAMDKGLTLA-SMLNDVPiSRWdagagSDWRPKNSPPQYAGPIRLRQGL 521
Cdd:TIGR02073 294 ADFFDdSNSGQvdGVRAPRSPGSTLKPFLYALALDDGLLHPdSLLKDVP-LRF-----GDYAPENFDKTFHGPVPAREAL 367
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 522 GQSKNVVMVRAMRAMGVDYAAEYLQRFGFP---AQNIVHTESLALGSASFTPMQVARGYAVMANGGFLIDPYFiskiend 598
Cdd:TIGR02073 368 ARSLNIPAVRLLERVGPPRFADFLRQAGLNllkPKSDYYGLSLALGGAEITLQDLANLYAMLANQGLSGPLRF------- 440
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 599 qggVLFEAKPKIACPECDIPVIYgntQKSDVLENTnveevavsqeqqnsavPMPELEQANQALvaqngtqeyaphvintp 678
Cdd:TIGR02073 441 ---LQTDAKRPERERLLSPGAAW---IVLDILKDR----------------PRPDDTLPLSAL----------------- 481
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 679 lafliksalntnifgePGWMGTGWraardlkrrdiggKTGTTNSSKDAWFSGYGPGVVTSVWIGfddhrrdlgrtTASGA 758
Cdd:TIGR02073 482 ----------------PTRLPLAW-------------KTGTSYGFRDAWAAGVSGRYTIGVWVG-----------NFDGK 521
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 759 IKDQISgyegGAKSAQPAWdaymKAVLEGVPE-QPLTPPPGIVTVNIDRSTGQLASGG--NSREEYFIEGTQPTQQAVHE 835
Cdd:TIGR02073 522 PNPGFF----GAAAAAPLL----FDILDALQAsEASTLPRPLKEVPGCLVLGNLPILPcpEQISTWFLPGGSPPTLSEPH 593
|
....*...
gi 446596466 836 VGTTIIDN 843
Cdd:TIGR02073 594 KPVVILIN 601
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
41-817 |
3.08e-72 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 253.92 E-value: 3.08e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 41 DVRLqIPMqVYSADGEliaqygekRRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGAST 120
Cdd:PRK09506 196 DPRL-ITM-LQSPNGE--------QRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGST 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 121 ITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEILELYLNKIYLGY----RAYGVGAAAQVYFGKTVDQLSLSEM 196
Cdd:PRK09506 266 LTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRILELYLNEVYLGQsgddQIRGFPLASLYYFGRPVEELSLDQQ 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 197 AVIAGLPKAPSTFNPLYSMDRAIARRNVVLSRMLSEGYITQAQYDQARSEPIDANYHApEIAFSAPYLSEMVRQEMYNRY 276
Cdd:PRK09506 346 ALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQPKG-GVISPQPAFMQMVRQELQAKL 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 277 GESAYE-DGYRIYTTITRKVQQAAQQAVrnnvldydmrhgyrgpanvlwkvgetawdskkitdtlkalptygpllpavvt 355
Cdd:PRK09506 425 GDKVKDlSGVKIFTTLDPVSQDAAEKAV---------------------------------------------------- 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 356 sanpQEATAALADGtsvslhmegmrwarpyrsdtqqgptpRKVTDvvqtgqqiwvrqvdndwwlaqvpeVNSALVSLNPQ 435
Cdd:PRK09506 453 ----EEGIPALKKQ--------------------------RKLSD------------------------LETAMVVVDRF 478
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 436 TGAVLALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLT--LASMLNDVPISRWDAGaGSDWRPKNSPPQYAG 513
Cdd:PRK09506 479 SGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPDKyrLNTWIADAPISLRQPN-GQVWSPQNDDRRFSG 557
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 514 PIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLIDPYFIS 593
Cdd:PRK09506 558 RVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALR 637
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 594 KIENDQGGVLFEAKPkiacpecdipviygntqksdvlentnveevavsqeQQNSAVPmpeleqANQALVAQNGTQEYAPH 673
Cdd:PRK09506 638 SVIAEDGKVLYQSFP-----------------------------------QAERAVP------AQAAYLTLYTMQQVVQR 676
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 674 vintplafliksalntnifgepgwmGTGWRAARDLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHrrdlGRT 753
Cdd:PRK09506 677 -------------------------GTGRQLGAKYPNLHLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRDNN----QPT 727
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446596466 754 TASGAikdqiSGyeggaksaqpAWDAYMKaVLEGVPEQPL--TPPPGIVTVNIDrSTGQLASGGNS 817
Cdd:PRK09506 728 KLYGA-----SG----------AMTIYQR-YLENQTPTPLnlTPPEDIVDMGVD-YDGNFVCGSGG 776
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
23-823 |
2.33e-66 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 236.28 E-value: 2.33e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 23 YGLYRyIEPQLpdvatlkdvrlqIPMQvYSADGEliaqygekRRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIF 102
Cdd:PRK14850 136 FSFLR-LDPKL------------IAML-YSPEGK--------KRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIG 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 103 RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEILELYLNKIYLGY----RAYGVGA 178
Cdd:PRK14850 194 RAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRFYSKDRILELYLNEVYLGQdgneQIRGFPL 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 179 AAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNVVLSRMLSEGYITQAQYDQARSEPIDANYHApEIA 258
Cdd:PRK14850 274 ASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNVQSKG-NII 352
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 259 FSAPYLSEMVRQEMYNRYGESAYE-DGYRIYTTITRKVQQAAQQAvrnnvldydMRHGYRgpanvlwkvgetawdskkit 337
Cdd:PRK14850 353 SSHPAFIQLVCEEFHKKIHYPFKNfSGTKIFTTLDYISQNAAEQA---------VKIGIP-------------------- 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 338 dtlkalptygpllpavvtsanpqeataaladgtsvslhmegmRWARPYRsdtqqgptprkvtdvvqtgqqiwvrqvdndw 417
Cdd:PRK14850 404 ------------------------------------------ILKRKKR------------------------------- 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 418 wlaqVPEVNSALVSLNPQTGAVLALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDK--GLTLASMLNDVPISrWD 495
Cdd:PRK14850 411 ----LKDLEVAMVIIDRFSGEVRALIGSSKPEFNGYNRALKARRSIGSLSKPITYLTALSQpeKYHLNTWISDTPIS-IK 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 496 AGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSASFTPMQVAR 575
Cdd:PRK14850 486 LDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSNYITPLPSISLGAINLTPMEVAQ 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 576 GYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKIAcpecdipviygntqksdvlentnveevavsqeqqnsavpmpele 655
Cdd:PRK14850 566 VFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSK-------------------------------------------- 601
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 656 qanqalvaqngtqeyapHVINTPLAFLIKSALNTNIFGepgwmGTGWRAARDLKRRDIGGKTGTTNSSKDAWFSGYGPGV 735
Cdd:PRK14850 602 -----------------HVESSQASYLTLYAMQQVVKS-----GTAKSLGTIFKEFSLAGKTGTTNNLVDSWFVGIDGKQ 659
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 736 VTSVWIGfddhrRDLGRTT----ASGAIKdqisgyeggaksaqpAWDAYMKavLEGVPEQPLTPPPGIVTVNIDRSTGQL 811
Cdd:PRK14850 660 VVITWIG-----RDNNHTTklygSSGAMK---------------IYKRYLQ--YQNPVPLVLKAPNNINMFYINNLGELF 717
|
810
....*....|..
gi 446596466 812 ASGGNSREEYFI 823
Cdd:PRK14850 718 CKKGNNQYNRML 729
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
66-584 |
6.01e-46 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 176.81 E-value: 6.01e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 66 RIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARnfFLSPE-RTLMRKIKEA 144
Cdd:PRK11240 62 RYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVAR--LLDPHpRTFGGKIRQL 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 145 FLAIRIEQLLNKNEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRAIARRNV 224
Cdd:PRK11240 140 WRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNK 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 225 VLSRMLSEGYITQAQYDQARSEPIdanyhapeiaFSAPylsemvRQEmynrygesayedgyriyttitrkvqqaaqqavr 304
Cdd:PRK11240 220 VLERMAEQGVWSAEQVKESREEPV----------WLAP------RQM--------------------------------- 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 305 nnvldydmrhgyrgpanvlwkvgetawdskkitdtlkalPTYGPLLPAVVTSANPQEataaladgtsvslhmegmrwarp 384
Cdd:PRK11240 251 ---------------------------------------PQLAPLFARMMLGKSKSD----------------------- 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 385 yrsdtqqgptprKVTDVVQTGQQiwvRQVDN--DWWLAQVPEVNS-ALVSLNPQTGAVLALVGGFDFN-QSKFNRA--TQ 458
Cdd:PRK11240 269 ------------KIVTTLDAGLQ---RRLEDlaLNWKGRLPPRSSlAMIVVDHTDMAVRGWVGSVDLNdDSRFGHVdmVN 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 459 ALRQVGSNIKPFLYTAAMDKGLT-LASMLNDVPiSRWDagagsDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMG 537
Cdd:PRK11240 334 AIRSPGSVLKPFVYGLALDDGLIhPASLLQDVP-RRTG-----DYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYG 407
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 446596466 538 VDYAAEYLQRFGFPAQNIVHTE---SLALGSASFTPMQVARGYAVMANGG 584
Cdd:PRK11240 408 PKRFAAKLRNVGLPLYLPAGAEpnlSLILGGAGARLEDMVAAYSAFARHG 457
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
63-246 |
2.23e-43 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 157.27 E-value: 2.23e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 63 EKRRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALfSGHASQGASTITQQLARNFFLSPERTLMRKIK 142
Cdd:PRK13481 42 ENKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTI-SDRDVQGGSTITQQVVKNYFYDNERSFTRKVK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 143 EAFLAIRIEQLLNKNEILELYLNKIYLGYRAYGVGAAAQVYFGKTVD-------QLSLSEMAVIAGLPKAPSTFNPLYSM 215
Cdd:PRK13481 121 ELFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNknsttmsHITVLQSAILASKVNAPSVYNINDMS 200
|
170 180 190
....*....|....*....|....*....|.
gi 446596466 216 DRAIARRNVVLSRMLSEGYITQAQYDQARSE 246
Cdd:PRK13481 201 ENFTQRVSTNLEKMKQQNYINETQYQQAMSQ 231
|
|
| PCB_OB |
pfam17092 |
Penicillin-binding protein OB-like domain; |
316-425 |
1.22e-39 |
|
Penicillin-binding protein OB-like domain;
Pssm-ID: 465343 [Multi-domain] Cd Length: 111 Bit Score: 142.00 E-value: 1.22e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 316 YRGPANVLWKVGETAWDSKKITDTLKALPTYGPLLPAVVTSANPQEATAALADGTSVSLHMEGMRWARPYRSDTQQGPTP 395
Cdd:pfam17092 1 YRGPEAHLDLPADWAERLAAIDEALADLPDVGGLRPAVVLSVSPKSARVGLRDGETGTIPGEGLRWARPYLSDKRQGPAP 80
|
90 100 110
....*....|....*....|....*....|.
gi 446596466 396 RKVTDVVQTGQQIWVRQVDND-WWLAQVPEV 425
Cdd:pfam17092 81 KSASDVLKPGDVIRVRPNGDGgWRLRQVPEV 111
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
69-213 |
7.96e-35 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 132.59 E-value: 7.96e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 69 VTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAI 148
Cdd:TIGR02070 58 RPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATW 137
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446596466 149 RIEQLLNKNEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAG-LPkapstfNPLY 213
Cdd:TIGR02070 138 MLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAvLP------NPKY 197
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
428-610 |
2.30e-23 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 105.29 E-value: 2.30e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 428 ALVSLNPQTGAVLALVGGFDFNQSKF---------NRATQALRQVGSNIKPFLYTAAMDKGL-TLASMLNDVPisRWDAG 497
Cdd:COG0768 250 AVVVMDPKTGEILAMASYPSFDPNLFvggpdeplrNRAVQGTYEPGSTFKPFTAAAALEEGViTPDTTFDCPG--YYRVG 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 498 agsDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGF--------P--AQNIVHTES----LAL 563
Cdd:COG0768 328 ---GRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLgqktgidlPgeASGLLPSPKrwypGET 404
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446596466 564 GSASF------TPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKI 610
Cdd:COG0768 405 ATMSIgqglsvTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGEVVKEEPEVL 457
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
428-599 |
2.71e-22 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 98.26 E-value: 2.71e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 428 ALVSLNPQTGAVLALVGGFDFNQSKF-----NRATQALRQVGSNIKPFLYTAAMDKG-LTLASMLNDVPISRWDAGAGSD 501
Cdd:pfam00905 2 SAVVLDPKTGEVLAMVGKPSYDPNGFigplrNRAVTSRYEPGSTFKPFTALAALDNGvLKPDETIFDWPGKQQGGKSIGD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 502 WRPKNsppqyAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGF--------PAQN--IVHTESLALGSASF--- 568
Cdd:pfam00905 82 WNQDQ-----VGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgnktgiglPGENagYLTPYWLEGATASFgig 156
|
170 180 190
....*....|....*....|....*....|....
gi 446596466 569 ---TPMQVARGYAVMANGGFLIDPYFISKIENDQ 599
Cdd:pfam00905 157 ltiTPLQQAQAYAAIANGGKLVPPHLVKSIEDKV 190
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
428-733 |
6.02e-16 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 82.19 E-value: 6.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 428 ALVSLNPQTGAVLALVG--GFDFNQ------SK-------------FNRATQALRQVGSNIKPFLYTAAMDKGLTLASMl 486
Cdd:TIGR03423 250 AVVVMDPRTGEILAMVStpSFDPNLfvdgisSKdykallndpdrplLNRAIQGVYPPGSTFKPVVALAALEEGVITPET- 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 487 ndvpiSRWDAGAGS-------DWRPKNSppqyaGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGF--------P 551
Cdd:TIGR03423 329 -----RIYCPGYFQlggrrfrCWKRGGH-----GRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKRFGFgqktgidlP 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 552 AQN--IVHTE-----------------SLALGSA--SFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVLFEAKPKI 610
Cdd:TIGR03423 399 GEKsgLVPSRewkrkrfgqpwypgdtlNVSIGQGyvLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEPEV 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 611 acpecdipviygntqksdvlentnVEEVAVSQEQqnsavpmpeLEQANQALVAqngtqeyaphVINTPLafliksalntn 690
Cdd:TIGR03423 479 ------------------------LRPLPISPEN---------LDVVREGMRD----------VVNGPG----------- 504
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446596466 691 ifgepgwmGTGWRAARDLKRRdIGGKTGT-------TNSSKD-----------AWFSGYGP 733
Cdd:TIGR03423 505 --------GTARRARLGLPYK-MAGKTGTaqvvslkQGEKYDaeqiperlrdhALFVAFAP 556
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
427-550 |
1.34e-03 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 42.45 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446596466 427 SALVSLNPQTGAVLALVGGFDFNQSKF---------------------NRATQALRQVGSNIKPFLYTAAMDKG-LTLAS 484
Cdd:PRK10795 272 AAVVVTDPRTGGILALVSTPSYDPNLFvdgisskdysgllndpnrpliNRATQGVYPPASTVKPYVAVSALSAGvITRNT 351
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446596466 485 MLNDvpiSRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGF 550
Cdd:PRK10795 352 SLFD---PGWWQLPGSEKRYRDWKKWGHGRLNVTKSLEESADTFFYQVAYDMGIDRLSEWMGKFGY 414
|
|
| |
