|
Name |
Accession |
Description |
Interval |
E-value |
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
9-659 |
0e+00 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 666.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 9 LRQLSISNSLRGAFLTGALLTLIVSMVSLYSWHEQSSQVRYSLDEYFPRIHSAFLIEGNLNLAVDQLNEFLLAPNTTVRL 88
Cdd:COG4192 5 LKRLGIGARLLLAFALSALLTLVASLVALFSWNSLSNQIRYILDDSLPKLQASLKLEENSNELVAALPEFAAATNTTERS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 89 QLRTQIIQHLDKIERLSQGLQLAERRQLAV--ILQDSRTLLAELDNALYNMFLVREKVSELSARIDWLHDDFTTELNSLV 166
Cdd:COG4192 85 QLRNQLNTQLADIEELLAELEQLTQDAGDLraAVADLRNLLQQLDSLLTQRIALRRRLQELLEQINWLHQDFNSELTPLL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 167 QDFTWQQGTLLDQIEANQgdaaqylqRSREVQNEQQQVYTLARIENQIVDDLRDRLnelksGNNDGMLVETHIRYLENLK 246
Cdd:COG4192 165 QEASWQQTRLLDSVETTE--------SLRNLQNELQLLLRLLAIENQIVSLLREVA-----AARDQADVDNLFDRLQYLK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 247 KTADENIRALDDWPSTITLRQTIDELLEIGMVKNKMPDTMRDYVAAQKALLDASRAREATLGRFRTLLEAQLGSSHQQMQ 326
Cdd:COG4192 232 DELDRNLQALKNYPSTITLRQLIDELLAIGSGEGGLPSLRRDELAAQATLEALAEENNSILEQLRTQISGLVGNSREQLV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 327 TFNQRLEQIVRVSGGLILVATLLALLLAWGLNHYFIRSRLVKRFTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRH 406
Cdd:COG4192 312 ALNQETAQLVQQSGILLLAIALLSLLLAVLINYFYVRRRLVKRLNALSDAMAAIAAGDLDVPIPVDGNDEIGRIARLLRV 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 407 TLGQLNMQRRQLEQEVAERKEIEADLRAMQDELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQAR 486
Cdd:COG4192 392 FRDQAIEKTQELETEIEERKRIEKNLRQTQDELIQAAKMAVVGQTMTSLAHELNQPLNAMSMYLFSAKKALEQENYAQLP 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 487 NTLTKAEGLINRIDAIIRSLRQFTRRAelETPLYPVDLRQTFVAAWELLAMRHQSRQGALSLPTDtVWVSGDEVRIQQVL 566
Cdd:COG4192 472 TSLDKIEGLIERMDKIIKSLRQFSRKS--DTPLQPVDLRQVIEQAWELVESRAKPQQITLHIPDD-LMVQGDQVLLEQVL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 567 VNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVAllPSLLKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLA 646
Cdd:COG4192 549 VNLLVNALDAVATQPQISVDLLSNAENLRVAISDNGNGWPLV--DKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYLA 626
|
650
....*....|...
gi 446601147 647 STLTRNACVVLQF 659
Cdd:COG4192 627 STLERGAMVILEF 639
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
361-659 |
1.97e-53 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 187.70 E-value: 1.97e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 361 FIRSRLVKRFTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRHTLGQLNMQRRQLEQEVAERKEIEADLRAMQDELI 440
Cdd:COG4191 55 LLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRELQEQLV 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 441 QTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQ-GQSGQARNTLTKAEGLINRIDAIIRSLRQFTRRAELEtpL 519
Cdd:COG4191 135 QSEKLAALGELAAGIAHEINNPLAAILGNAELLRRRLEDePDPEELREALERILEGAERAAEIVRSLRAFSRRDEEE--R 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 520 YPVDLRQTFVAAWELLamRHQSRQGA----LSLPTDTVWVSGDEVRIQQVLVNVLANALDACSHDAA--IAVTWQTQGEA 593
Cdd:COG4191 213 EPVDLNELIDEALELL--RPRLKARGieveLDLPPDLPPVLGDPGQLEQVLLNLLINAIDAMEEGEGgrITISTRREGDY 290
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446601147 594 LEVYIADNGPGWPVALLPSLLKPFTTSKAV--GLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQF 659
Cdd:COG4191 291 VVISVRDNGPGIPPEVLERIFEPFFTTKPVgkGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITL 358
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
360-663 |
1.99e-33 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 133.16 E-value: 1.99e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 360 YFIRSRLVKRFTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRHTLGQLNMQRRQLEQ------------------- 420
Cdd:COG5000 27 LLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQREELEErrryletilenlpagvivl 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 421 ----------------------------------------------EVAERKEIEADLRAMQD----------------- 437
Cdd:COG5000 107 dadgritlanpaaerllgipleeligkpleellpeldlaellrealERGWQEEIELTRDGRRTllvrasplrddgyvivf 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 438 ----ELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQARNTLTKAEGLINRIDA---IIRSLRQFT 510
Cdd:COG5000 187 dditELLRAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRKLADKLEEDREDLERALDTIIRQVDRlkrIVDEFLDFA 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 511 RRAELEtpLYPVDLRQTFVAAWELLAMRHQSRQGAL--SLPTDTVWVSGDEVRIQQVLVNVLANALDACSHDAAIAVTWQ 588
Cdd:COG5000 267 RLPEPQ--LEPVDLNELLREVLALYEPALKEKDIRLelDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTR 344
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446601147 589 TQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQFSVTD 663
Cdd:COG5000 345 REDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPLAE 419
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
360-659 |
3.12e-32 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 127.33 E-value: 3.12e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 360 YFIRSRLVKRFTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRHTLGQLNMQRRQLEQEVAERKEIEADLRAMQDEL 439
Cdd:COG0642 23 LLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 440 IQTAKLAVvGQTMTTLAHEINQPLNALSMYLftagRAIEQGQSGQARNTLTKAEGLINRIDAIIRSLRQFTR--RAELET 517
Cdd:COG0642 103 LEEANEAK-SRFLANVSHELRTPLTAIRGYL----ELLLEELDEEQREYLETILRSADRLLRLINDLLDLSRleAGKLEL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 518 PLYPVDLRQTFVAAWELLAMRHQSRQGALSL--PTDTVWVSGDEVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALE 595
Cdd:COG0642 178 EPEPVDLAELLEEVVELFRPLAEEKGIELELdlPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREGDRVR 257
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446601147 596 VYIADNGPGWPVALLPSLLKPFTTSKAV----GLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQF 659
Cdd:COG0642 258 ISVEDTGPGIPPEDLERIFEPFFRTDPSrrggGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTL 325
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
417-659 |
1.56e-29 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 117.32 E-value: 1.56e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 417 QLEQEVAERKEIEAdlraMQDELIqtaklavvgqtmTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQARnTLTKAEGLI 496
Cdd:COG2205 1 ELEEALEELEELER----LKSEFL------------ANVSHELRTPLTSILGAAELLLDEEDLSPEERRE-LLEIIRESA 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 497 NRIDAIIRSLRQFTR--RAELETPLYPVDLRQTFVAAWELLAMRHQSRQGALSL--PTDTVWVSGDEVRIQQVLVNVLAN 572
Cdd:COG2205 64 ERLLRLIEDLLDLSRleSGKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELdlPPELPLVYADPELLEQVLANLLDN 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 573 ALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPF----TTSKAVGLGIGLSISVSLMAQMKGDLRLAST 648
Cdd:COG2205 144 AIKYSPPGGTITISARREGDGVRISVSDNGPGIPEEELERIFERFyrgdNSRGEGGTGLGLAIVKRIVEAHGGTIWVESE 223
|
250
....*....|.
gi 446601147 649 LTRNACVVLQF 659
Cdd:COG2205 224 PGGGTTFTVTL 234
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
420-659 |
2.07e-23 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 102.23 E-value: 2.07e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 420 QEVAERKEIEAdlramqdELIQTAKLAVVGQTMTTLAHEINQPLNALSMYlftAGRAIEQGQSGQARNTLTKAEGLINRI 499
Cdd:COG3852 114 RDITERKRLER-------ELRRAEKLAAVGELAAGLAHEIRNPLTGIRGA---AQLLERELPDDELREYTQLIIEEADRL 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 500 DAIIRSLRQFTRRAELEtpLYPVDLRqtfvaawELLA-----MRHQSRQGA---LSLPTDTVWVSGDEVRIQQVLVNVLA 571
Cdd:COG3852 184 NNLVDRLLSFSRPRPPE--REPVNLH-------EVLErvlelLRAEAPKNIrivRDYDPSLPEVLGDPDQLIQVLLNLVR 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 572 NALDACSHDAAIAVT----------WQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLSISVSLMAQMKG 641
Cdd:COG3852 255 NAAEAMPEGGTITIRtrverqvtlgGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKEKGTGLGLAIVQKIVEQHGG 334
|
250
....*....|....*...
gi 446601147 642 DLRLASTLTRNACVVLQF 659
Cdd:COG3852 335 TIEVESEPGKGTTFRIYL 352
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
420-657 |
5.43e-23 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 103.89 E-value: 5.43e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 420 QEVAERKEieadlraMQDELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQARNTLTKAeglINRI 499
Cdd:PRK11360 369 SDLTERKR-------LQRRVARQERLAALGELVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQEYLSVVLRE---VDRL 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 500 DAIIRSLRQFTRRAELEtpLYPVDLRQTFVAAWELLAMRHQSRQGALSLPTD----TVWVSGDEVRiqQVLVNVLANALD 575
Cdd:PRK11360 439 NKVIDQLLEFSRPRESQ--WQPVSLNALVEEVLQLFQTAGVQARVDFETELDnelpPIWADPELLK--QVLLNILINAVQ 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 576 ACSHDAAIAV-TWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNAC 654
Cdd:PRK11360 515 AISARGKIRIrTWQYSDGQVAVSIEDNGCGIDPELLKKIFDPFFTTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTT 594
|
...
gi 446601147 655 VVL 657
Cdd:PRK11360 595 FTL 597
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
290-659 |
5.76e-23 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 101.55 E-value: 5.76e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 290 VAAQKALLDASRAREATLGRFRTLLEAQLGSSHQQMQTFNQRLEQIVRVSGGLILVATLLALLLAWGLNHYFIRSRLVKR 369
Cdd:COG5002 23 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 370 FTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRHTLGQLNMQRRQLEQEVAERKEIEAdlraMQDELIQTAklavvg 449
Cdd:COG5002 103 ILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQ----MRREFVANV------ 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 450 qtmttlAHEINQPLNALSMYLftagRAIEQGQSG---QARNTLTKAEGLINRIDAIIRSLRQFTR--RAELETPLYPVDL 524
Cdd:COG5002 173 ------SHELRTPLTSIRGYL----ELLLDGAADdpeERREYLEIILEEAERLSRLVNDLLDLSRleSGELKLEKEPVDL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 525 RQTFVAAWELLAMRHQSRQGALSL--PTDTVWVSGDEVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVYIADNG 602
Cdd:COG5002 243 AELLEEVVEELRPLAEEKGIELELdlPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQVRISVRDTG 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446601147 603 PGWPVALLPSLLKPFTTSKAV------GLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQF 659
Cdd:COG5002 323 IGIPEEDLPRIFERFYRVDKSrsretgGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITL 385
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
557-659 |
1.44e-21 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 90.02 E-value: 1.44e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 557 GDEVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAV-----GLGIGLSI 631
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRsrkigGTGLGLSI 80
|
90 100
....*....|....*....|....*...
gi 446601147 632 SVSLMAQMKGDLRLASTLTRNACVVLQF 659
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITL 108
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
562-659 |
6.68e-20 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 84.96 E-value: 6.68e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAV----GLGIGLSISVSLMA 637
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSreggGTGLGLAIVRRIVE 80
|
90 100
....*....|....*....|..
gi 446601147 638 QMKGDLRLASTLTRNACVVLQF 659
Cdd:cd00075 81 AHGGRITVESEPGGGTTFTVTL 102
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
176-662 |
7.32e-20 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 93.31 E-value: 7.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 176 LLDQIEANQGDAAQYLQRSREVQNEQQQVYTLARIENQIVDDLRDRLNELKSGNNDGMLVETHIRYLENLKKTADENIRA 255
Cdd:COG4251 19 LLLLLLLLVLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLELALVLLALLL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 256 LDDWPSTITLRQTIDELLEIGMVKNKMPDTMRDYVAAQKALLDASRAREATLGRFRTLLEAQLGSSHQQMQTFNQRLEQI 335
Cdd:COG4251 99 VLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAEL 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 336 VRVSGGLILVATLLALLLAWGLNHYFIRSRLVKRFTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRHTLGQLNMQR 415
Cdd:COG4251 179 ELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELR 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 416 RQLEQEVAERKEIEADLRAMQDELIQTAKLAvvgqtmttlAHEINQPLNALSMYLFTAGRAIEQGQSGQARNTLTKAEGL 495
Cdd:COG4251 259 LELEELEEELEERTAELERSNEELEQFAYVA---------SHDLREPLRKISGFSQLLEEDYGDKLDEEGREYLERIRDA 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 496 INRIDAIIRSLRQFTRRAELETPLYPVDLRQTFVAAWELLAMRHQSRQGALS---LPTdtvwVSGDEVRIQQVLVNVLAN 572
Cdd:COG4251 330 AERMQALIDDLLAYSRVGRQELEFEPVDLNELLEEVLEDLEPRIEERGAEIEvgpLPT----VRGDPTLLRQVFQNLISN 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 573 ALDACSHDAA--IAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPF----TTSKAVGLGIGLSISVSLMAQMKGDLRLA 646
Cdd:COG4251 406 AIKYSRPGEPprIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFqrlhSRDEYEGTGIGLAIVKKIVERHGGRIWVE 485
|
490
....*....|....*.
gi 446601147 647 STLTRNACvvlqFSVT 662
Cdd:COG4251 486 SEPGEGAT----FYFT 497
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
557-659 |
1.68e-18 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 81.26 E-value: 1.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 557 GDEVRIQQVLVNVLANALDACSHDAAIAVTwQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAV---GLGIGLSISV 633
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVT-LSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRgggGTGLGLSIVR 79
|
90 100
....*....|....*....|....*.
gi 446601147 634 SLMAQMKGDLRLASTLTRNACVVLQF 659
Cdd:pfam02518 80 KLVELLGGTITVESEPGGGTTVTLTL 105
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
389-663 |
5.21e-18 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 88.55 E-value: 5.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 389 IPVYGRDELGRIARLLRHTLGQLNMQRRQLEQEVAERKeieadlRAMqDELIQTAKLAVVGQT--MTTLAHEINQPLN-- 464
Cdd:PRK15347 344 LPENRLDELGSIAKAYNQLLDTLNEQYDTLENKVAERT------QAL-AEAKQRAEQANKRKSehLTTISHEIRTPLNgv 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 465 --ALSMYLFTagrAIEQGQSGQARNTLTKAEGLInridAIIRSLRQFTR----RAEL---ETPLYPVdLRQTfvaaweLL 535
Cdd:PRK15347 417 lgALELLQNT---PLTAEQMDLADTARQCTLSLL----AIINNLLDFSRiesgQMTLsleETALLPL-LDQA------ML 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 536 AMRHQSRQGALSLPTdtvWVSG--------DEVRIQQVLVNVLANALDACSHdAAIAVTWQTQGEALEVYIADNGPGWPV 607
Cdd:PRK15347 483 TIQGPAQSKSLTLRT---FVGAhvplylhlDSLRLRQILVNLLGNAVKFTET-GGIRLRVKRHEQQLCFTVEDTGCGIDI 558
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 446601147 608 ALLPSLLKPF--TTSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQFSVTD 663
Cdd:PRK15347 559 QQQQQIFTPFyqADTHSQGTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLPLNE 616
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
415-657 |
6.76e-18 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 86.76 E-value: 6.76e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 415 RRQLEQEVAeRKEieadlramqdeliqtaKLAVVGQTMTTLAHEINQPLNALSMYL-FTAGRAIEQGQSGQARNTLTKAE 493
Cdd:PRK10364 221 RQLLQDEMK-RKE----------------KLVALGHLAAGVAHEIRNPLSSIKGLAkYFAERAPAGGEAHQLAQVMAKEA 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 494 GLINRIdaiIRSLRQFTRRAELEtpLYPVDLRQTFVAAWELLAMRHQSRQGALSL-PTDTV-WVSGDEVRIQQVLVNVLA 571
Cdd:PRK10364 284 DRLNRV---VSELLELVKPTHLA--LQAVDLNDLINHSLQLVSQDANSREIQLRFtANDTLpEIQADPDRLTQVLLNLYL 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 572 NALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLASTLTR 651
Cdd:PRK10364 359 NAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGK 438
|
....*.
gi 446601147 652 NACVVL 657
Cdd:PRK10364 439 GATFTL 444
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
562-647 |
2.75e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 77.50 E-value: 2.75e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACS--HDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAV--GLGIGLSISVSLMA 637
Cdd:cd16976 1 IQQVLMNLLQNALDAMGkvENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPVgkGTGLGLSISYGIVE 80
|
90
....*....|
gi 446601147 638 QMKGDLRLAS 647
Cdd:cd16976 81 EHGGRLSVAN 90
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
424-659 |
1.77e-15 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 79.63 E-value: 1.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 424 ERKEIEADLRamqdeliQTAKLAVVGQTMTTLAHEINQPLNALSMYL-FTAGRAIEQGQsgQARNTLTKAeglINRIDAI 502
Cdd:COG5809 253 ERKKLEELLR-------KSEKLSVVGELAAGIAHEIRNPLTSLKGFIqLLKDTIDEEQK--TYLDIMLSE---LDRIESI 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 503 IRSLRQFTRRAEL---ETPLYPVdLRQTFvaawELL---AMRHqSRQGALSLPTDTVWVSGDEVRIQQVLVNVLANALDA 576
Cdd:COG5809 321 ISEFLVLAKPQAIkyePKDLNTL-IEEVI----PLLqpqALLK-NVQIELELEDDIPDILGDENQLKQVFINLLKNAIEA 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 577 CSHDAAIAV-TWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNACV 655
Cdd:COG5809 395 MPEGGNITIeTKAEDDDKVVISVTDEGCGIPEERLKKLGEPFYTTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTF 474
|
....
gi 446601147 656 VLQF 659
Cdd:COG5809 475 SITL 478
|
|
| PEP_his_kin |
TIGR02916 |
putative PEP-CTERM system histidine kinase; Members of this protein family have a novel ... |
430-657 |
6.34e-15 |
|
putative PEP-CTERM system histidine kinase; Members of this protein family have a novel N-terminal domain, a single predicted membrane-spanning helix, and a predicted cystosolic histidine kinase domain. We designate this protein PrsK, and its companion DNA-binding response regulator protein (TIGR02915) PrsR. These predicted signal-transducing proteins appear to enable enhancer-dependent transcriptional activation. The prsK gene is often associated with exopolysaccharide biosynthesis genes. [Protein fate, Protein and peptide secretion and trafficking, Signal transduction, Two-component systems]
Pssm-ID: 274349 [Multi-domain] Cd Length: 679 Bit Score: 78.22 E-value: 6.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 430 ADLRAMQdELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQarNTLTKAEGLINRIDAIIRSLRQF 509
Cdd:TIGR02916 458 AQMEASE-ALAEARQFEAFNRMSAFVVHDLKNLVAQLSLLLRNAERHKDNPEFQD--DMLETVENAVNRMKKLLAQLRSK 534
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 510 TRRAELETpLYPVDLRQTFVAAwellaMRHQSRQGALSLPTDtVWVSGDEVRIQQVLVNVLANALDACSHDAAIAVTWQT 589
Cdd:TIGR02916 535 GLEEEKLC-VDLVDLLRRAIAS-----KRAQGPRPEVSIDTD-LSVRADRERLERVLGHLVQNALEATPGEGRVAIRVER 607
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446601147 590 QGEALEVYIADNGPGWPVALLPS-LLKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNACVVL 657
Cdd:TIGR02916 608 ECGAARIEIEDSGCGMSPAFIRErLFKPFDTTKGAGMGIGVYECRQYVEEIGGRIEVESTPGQGTIFTL 676
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
420-647 |
1.12e-14 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 77.08 E-value: 1.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 420 QEVAERKEIEAdlramqdELIQTAKLAVVGQTMTTLAHEINQPLNALSMY--LFTAGRaIEQGQSGQarntLTKAEglIN 497
Cdd:COG5805 266 RDITEKKEAEE-------LMARSEKLSIAGQLAAGIAHEIRNPLTSIKGFlqLLQPGI-EDKEEYFD----IMLSE--LD 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 498 RIDAIIRSLRQFTRRAELETPlyPVDLRQTFVAAWELL---AMRHQsRQGALSLPTDTVWVSGDEVRIQQVLVNVLANAL 574
Cdd:COG5805 332 RIESIISEFLALAKPQAVNKE--KENINELIQDVVTLLeteAILHN-IQIRLELLDEDPFIYCDENQIKQVFINLIKNAI 408
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446601147 575 DACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLAS 647
Cdd:COG5805 409 EAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFTTKEKGTGLGLMVSYKIIENHNGTIDIDS 481
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
562-662 |
6.84e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 68.19 E-value: 6.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACSH------DAAIAVTWQTQGeALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLSISVSL 635
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEggcerrELTIRTSPADDR-AVTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRSI 79
|
90 100
....*....|....*....|....*..
gi 446601147 636 MAQMKGDLRLASTLTRNACvvlqFSVT 662
Cdd:cd16920 80 IEAHGGRLSVESPAGGGAT----FQFT 102
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
562-653 |
5.53e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 65.52 E-value: 5.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACSHDAAIAV-TWQTQGEALeVYIADNGPGWPVALLPSLLKPFTTSKAV--GLGIGLSISVSLMAQ 638
Cdd:cd16943 4 LNQVLLNLLVNAAQAMEGRGRITIrTWAHVDQVL-IEVEDTGSGIDPEILGRIFDPFFTTKPVgeGTGLGLSLSYRIIQK 82
|
90
....*....|....*
gi 446601147 639 MKGDLRLASTLTRNA 653
Cdd:cd16943 83 HGGTIRVASVPGGGT 97
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
390-657 |
1.47e-12 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 70.26 E-value: 1.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 390 PVYGRDELGRIARLLRHtlgqlnMqRRQLEQevaeRKEIEadlramqdeliqtaklavvgQTMTTLAHEINQPLNALSmy 469
Cdd:PRK11100 229 PKLGSSELRELAQALES------M-RVKLEG----KAYVE--------------------QYVQTLTHELKSPLAAIR-- 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 470 lfTAGRAIEQGQSGQAR-----NTLTKAEglinRIDAIIRSLRQFTR---RAELETPLyPVDLRQTFVAAWELLAMRHQS 541
Cdd:PRK11100 276 --GAAELLQEDPPPEDRarftgNILTQSA----RLQQLIDRLLELARleqRQELEVLE-PVALAALLEELVEAREAQAAA 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 542 RQGALSLPTDTVWVSGDEVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLP-------SLL 614
Cdd:PRK11100 349 KGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPDYALPriferfySLP 428
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 446601147 615 KPFTTSKAVGLgiGLSISVSLMAQMKGDLRLASTLTRNACVVL 657
Cdd:PRK11100 429 RPANGRKSTGL--GLAFVREVARLHGGEVTLRNRPEGGVLATL 469
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
375-661 |
2.16e-12 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 70.32 E-value: 2.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 375 QAVVQIGLGRTDSTIP----VYGRDELGRIARLLRHTLGQLNMQRRQLEQEVAERKeieADLRAMQDELIQT---AKLAV 447
Cdd:PRK11466 365 QALQRLLDGDIDSPFPetagVRELDTIGRLMDAFRSNVHALNRHREQLAAQVKART---AELQELVIEHRQAraeAEKAS 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 448 VGQT--MTTLAHEINQPLNALsmyLFTAGRAIEQGQSGQARNTLTKAEGLINRIDAIIRSLRQF-------TRRAELETP 518
Cdd:PRK11466 442 QAKSafLAAMSHEIRTPLYGI---LGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYsaieaggKNVSVSDEP 518
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 519 LYPvdlRQTFVAAWELLAMRHQSRQGALS------LPTdtvWVSGDEVRIQQVLVNVLANALDAcSHDAAIAVTWQTQGE 592
Cdd:PRK11466 519 FEP---RPLLESTLQLMSGRVKGRPIRLAtdiaddLPT---ALMGDPRRIRQVITNLLSNALRF-TDEGSIVLRSRTDGE 591
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446601147 593 ALEVYIADNGPGWPVALLPSLLKPFT--TSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQFSV 661
Cdd:PRK11466 592 QWLVEVEDSGCGIDPAKLAEIFQPFVqvSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPL 662
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
381-662 |
8.03e-11 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 65.47 E-value: 8.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 381 GLGRTDSTIPVYgRDELGriarLLRHTLGQLN--MQRRQLEQEvaeRKEIEADLRAMQdeliqtaKLAVVGQTMTTLAHE 458
Cdd:PRK13837 396 GLGRQRYGLRPP-AGELQ----LLELALDCLAhaIERRRLETE---RDALERRLEHAR-------RLEAVGTLASGIAHN 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 459 INQPLNALSMYLFTAGRAIEQGQSgqARNTLTKAEGLINRIDAIIRSLRQFTRRAELetPLYPVDLRQTFVAAWELLAMR 538
Cdd:PRK13837 461 FNNILGAILGYAEMALNKLARHSR--AARYIDEIISAGARARLIIDQILAFGRKGER--NTKPFDLSELVTEIAPLLRVS 536
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 539 HQSR-QGALSLPTDTVWVSGDEVRIQQVLVNVLANALDACSHDAAIAVTWQTQ---------------GEALEVYIADNG 602
Cdd:PRK13837 537 LPPGvELDFDQDQEPAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRAklrapkvlshgvlppGRYVLLRVSDTG 616
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 603 PGWPVALLPSLLKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQFSVT 662
Cdd:PRK13837 617 AGIDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDVYLPPS 676
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
558-659 |
3.32e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 57.55 E-value: 3.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 558 DEVRIQQVLVNVLANALDACS--HDAAIAVTWQT---QGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLSIS 632
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEgrPSDVGEVRIRVeadQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGLAIV 80
|
90 100
....*....|....*....|....*..
gi 446601147 633 VSLMAQMKGDLRLASTLTRNACVVLQF 659
Cdd:cd16944 81 KKIMEEHGGRISLSNREAGGACIRIIL 107
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
562-641 |
1.25e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 55.87 E-value: 1.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACSH-DAAIAVTWQTQGE----------ALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLS 630
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGsGGEIILRTRTQRQvtlghprhrlALRVSVIDNGPGIPPDLQDTIFYPMVSGRENGTGLGLA 80
|
90
....*....|.
gi 446601147 631 ISVSLMAQMKG 641
Cdd:cd16918 81 IAQNIVSQHGG 91
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
489-661 |
1.54e-08 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 57.31 E-value: 1.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 489 LTKAEGL-INR----IDAIIRSLRQFTR--RAELETPLYPVDLR---QTFVAAWELLamrHQSRQGALSLPTDTVWVSGD 558
Cdd:PRK10604 240 LSAAESQaLNRdigqLEALIEELLTYARldRPQNELHLSEPDLPawlSTHLADIQAV---TPEKTVRLDTPHQGDYGALD 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 559 EVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVyiADNGPGWPVALLPSLLKPFT------TSKAVGLGIGLSIS 632
Cdd:PRK10604 317 MRLMERVLDNLLNNALRYAHSRVRVSLLLDGNQACLIV--EDDGPGIPPEERERVFEPFVrldpsrDRATGGCGLGLAIV 394
|
170 180
....*....|....*....|....*....
gi 446601147 633 VSLMAQMKGDLRLASTLTRNACVVLQFSV 661
Cdd:PRK10604 395 HSIALAMGGSVNCDESELGGARFSFSWPV 423
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
545-631 |
3.39e-08 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 56.97 E-value: 3.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 545 ALSLPTDTVWVSGDEVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFT----TS 620
Cdd:PRK10490 762 NLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFArgnkES 841
|
90
....*....|.
gi 446601147 621 KAVGLGIGLSI 631
Cdd:PRK10490 842 AIPGVGLGLAI 852
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
433-663 |
3.72e-08 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 56.60 E-value: 3.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 433 RAMQDELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQAR--NTLTKAEGLINRIDAIIRSLRQFT 510
Cdd:PRK13557 148 RDAEDALRQAQKMEALGQLTGGIAHDFNNLLQVMSGYLDVIQAALSHPDADRGRmaRSVENIRAAAERAATLTQQLLAFA 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 511 RRAELETplYPVDLrQTFVAAWELLAMRhqSRQGALSLPTD---TVWVSG-DEVRIQQVLVNVLANALDACSHdaAIAVT 586
Cdd:PRK13557 228 RKQRLEG--RVLNL-NGLVSGMGELAER--TLGDAVTIETDlapDLWNCRiDPTQAEVALLNVLINARDAMPE--GGRVT 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 587 WQTQGEALE-----------------VYIADNGPGWPVALLPSLLKPFTTSK--AVGLGIGLSISVSLMAQMKGDLRLAS 647
Cdd:PRK13557 301 IRTRNVEIEdedlamyhglppgryvsIAVTDTGSGMPPEILARVMDPFFTTKeeGKGTGLGLSMVYGFAKQSGGAVRIYS 380
|
250
....*....|....*.
gi 446601147 648 TLTRNACVVLQFSVTD 663
Cdd:PRK13557 381 EVGEGTTVRLYFPASD 396
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
562-646 |
3.77e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 51.68 E-value: 3.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACShdAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKA----VGLGIGLSISVSLMA 637
Cdd:cd16950 1 LKRVLSNLVDNALRYGG--GWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNargtSGTGLGLAIVQRISD 78
|
....*....
gi 446601147 638 QMKGDLRLA 646
Cdd:cd16950 79 AHGGSLTLA 87
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
562-649 |
1.29e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 50.18 E-value: 1.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACSHDAAIAVTW----QTQGEALEVYIADNGPGWPVALLPSLLKPF------TTSKAVGLGIGLSI 631
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEGEVTLRVSleeeEEDGVQLRFSVEDTGIGIPEEQQARLFEPFsqadssTTRKYGGTGLGLAI 80
|
90
....*....|....*...
gi 446601147 632 SVSLMAQMKGDLRLASTL 649
Cdd:cd16922 81 SKKLVELMGGDISVESEP 98
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
558-647 |
5.52e-07 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 52.01 E-value: 5.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 558 DEVRIQQVLVNVLANALDACSH-DAAIAVTWQT------QGE----ALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLG 626
Cdd:PRK11073 234 DPDQIEQVLLNIVRNALQALGPeGGTITLRTRTafqltlHGEryrlAARIDIEDNGPGIPPHLQDTLFYPMVSGREGGTG 313
|
90 100
....*....|....*....|.
gi 446601147 627 IGLSISVSLMAQMKGDLRLAS 647
Cdd:PRK11073 314 LGLSIARNLIDQHSGKIEFTS 334
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
410-606 |
6.39e-07 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 52.26 E-value: 6.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 410 QLNMQRRQLEQEVAERKEIEadlraMQDELIQ--------TAKLAVVGQTMTTLAHEINQPLNALSMylftagrAIEQGQ 481
Cdd:PRK09303 110 GENLQPSEIDSGRYSQELLQ-----LSDELFVlrqenetlLEQLKFKDRVLAMLAHDLRTPLTAASL-------ALETLE 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 482 SGQARNTLTKAEGLINR-----------IDAIIRSLRQFTRRAELETPLYP--VDLRQTFVAAWELLAMRHQSRQGAL-- 546
Cdd:PRK09303 178 LGQIDEDTELKPALIEQlqdqarrqleeIERLITDLLEVGRTRWEALRFNPqkLDLGSLCQEVILELEKRWLAKSLEIqt 257
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446601147 547 SLPTDTVWVSGDEVRIQQVLVNVLANALDACSHDAAIAVTW---QTQgeALEVYIADNGPGWP 606
Cdd:PRK09303 258 DIPSDLPSVYADQERIRQVLLNLLDNAIKYTPEGGTITLSMlhrTTQ--KVQVSICDTGPGIP 318
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
558-659 |
1.28e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 47.46 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 558 DEVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVG-----LGIGLSIS 632
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRrsgghYGMGLYIA 80
|
90 100
....*....|....*....|....*..
gi 446601147 633 VSLMAQMKGDLRLASTLTRNACVVLQF 659
Cdd:cd16975 81 KNLVEKHGGSLIIENSQKGGAEVTVKI 107
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
495-657 |
2.66e-06 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 49.97 E-value: 2.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 495 LINRIDAIIRSLRQFTRRA----ELETPLY-PVDLRQTFVAAW-----ELLAMRHQSRQgaLSLPTDTVWVSGDEVRIQQ 564
Cdd:PRK10755 173 LIARLDQMMHTVEQLLQLAragqSFSSGHYqTVKLLEDVILPSqdelsEMLEQRQQTLL--LPESAADITVQGDATLLRL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 565 VLVNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFT--TSKAVGLGIGLSIsVSLMAQM-KG 641
Cdd:PRK10755 251 LLRNLVENAHRYSPEGSTITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVrmDSRYGGIGLGLSI-VSRITQLhHG 329
|
170
....*....|....*....
gi 446601147 642 DLRLASTLTR---NACVVL 657
Cdd:PRK10755 330 QFFLQNRQERsgtRAWVWL 348
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
521-649 |
5.04e-06 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 49.39 E-value: 5.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 521 PVDLRQTFVAAWELLAMRHQSRQGALSLPTDTVWVSGDEVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVYIAD 600
Cdd:PRK09835 335 MLDLADEVGKVFDFFEAWAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVEN 414
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 446601147 601 NGPGWPVALLPSL------LKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLASTL 649
Cdd:PRK09835 415 PGTPIAPEHLPRLfdrfyrVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSDA 469
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
562-644 |
5.57e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 45.39 E-value: 5.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACshDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPF------TTSKAVGLGIGLSISVSL 635
Cdd:cd16949 1 LARALENVLRNALRYS--PSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFyrvdsaRDRESGGTGLGLAIAERA 78
|
....*....
gi 446601147 636 MAQMKGDLR 644
Cdd:cd16949 79 IEQHGGKIK 87
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
553-647 |
9.03e-06 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 49.20 E-value: 9.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 553 VWVSGDEVRIQQVLVNVLANALDAcSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPF------TTSKAVGLG 626
Cdd:PRK10841 554 VALNGDPMRLQQVISNLLSNAIKF-TDTGCIVLHVRVDGDYLSFRVRDTGVGIPAKEVVRLFDPFfqvgtgVQRNFQGTG 632
|
90 100
....*....|....*....|.
gi 446601147 627 IGLSISVSLMAQMKGDLRLAS 647
Cdd:PRK10841 633 LGLAICEKLINMMDGDISVDS 653
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
565-659 |
2.00e-05 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 47.54 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 565 VLVNVLANALDACSHDAA----IAVTWQTQGEALEVYIADNGPGWPVALLPSLLKP-FTTSKAVGLGIGLSISVSLMAQM 639
Cdd:COG3290 285 ILGNLLDNAIEAVEKLPEeerrVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERgFSTKLGEGRGLGLALVKQIVEKY 364
|
90 100
....*....|....*....|
gi 446601147 640 KGDLRLASTLTRNACVVLQF 659
Cdd:COG3290 365 GGTIEVESEEGEGTVFTVRL 384
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
564-636 |
2.55e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 43.72 E-value: 2.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 564 QVLVNVLANALDACSHDAA-IAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVGL------GIGLSISVSLM 636
Cdd:cd16953 3 QVLRNLIGNAISFSPPDTGrITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEafgqhsGLGLSISRQII 82
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
562-657 |
6.96e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 42.42 E-value: 6.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACSHDAAIAVTwqTQGEALEVYIADNGPGWPVALLPSLLKPFT------TSKAVGLGIGLSISVSL 635
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVRIALL--VSGGRLTLIVEDDGPGIPAAARERVFEPFVrldpsrDRATGGFGLGLAIVHRV 78
|
90 100
....*....|....*....|..
gi 446601147 636 MAQMKGDLRLASTLTRNACVVL 657
Cdd:cd16939 79 ALWHGGHVECDDSELGGACFRL 100
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
562-655 |
8.85e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 41.93 E-value: 8.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 562 IQQVLVNVLANALDACSHD--AAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPF----TTSKAVGLGIGLSISVSL 635
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRrpPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFqrlhSREEYEGTGVGLAIVRKI 80
|
90 100
....*....|....*....|
gi 446601147 636 MAQMKGDLRLASTLTRNACV 655
Cdd:cd16921 81 IERHGGRIWLESEPGEGTTF 100
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
558-646 |
1.16e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 41.68 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 558 DEVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLP-------SLLKPFTTSKAVGLgiGLS 630
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNrvferfySLPRPHSGQKSTGL--GLA 78
|
90
....*....|....*.
gi 446601147 631 ISVSLMAQMKGDLRLA 646
Cdd:cd16945 79 FVQEVAQLHGGRITLR 94
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
492-631 |
1.16e-04 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 44.90 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 492 AEGLINRI---DAIIRslrQFTR--RAELETPLYPVDLRQtfVAAWELLAMRHQSRQGALSLPTDTVWVSGDEVRIQQVL 566
Cdd:PRK09467 262 AESINKDIeecNAIIE---QFIDylRTGQEMPMEMADLNA--LLGEVIAAESGYEREIETALQPGPIEVPMNPIAIKRAL 336
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446601147 567 VNVLANALDACSHDaaIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTT-SKA---VGLGIGLSI 631
Cdd:PRK09467 337 ANLVVNAARYGNGW--IKVSSGTEGKRAWFQVEDDGPGIPPEQLKHLFQPFTRgDSArgsSGTGLGLAI 403
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
563-647 |
1.18e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 41.98 E-value: 1.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 563 QQVLVNVLANALDACSHDAAIAVTWQTQ---------------GEALEVYIADNGPGWPVALLPSLLKPFTTSKAV--GL 625
Cdd:cd16919 2 ELAILNLAVNARDAMPEGGRLTIETSNQrvdadyalnyrdlipGNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKEVgkGT 81
|
90 100
....*....|....*....|..
gi 446601147 626 GIGLSISVSLMAQMKGDLRLAS 647
Cdd:cd16919 82 GLGLSMVYGFVKQSGGHLRIYS 103
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
558-643 |
1.20e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 41.68 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 558 DEVRIQQVLVNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPF------TTSKAVGLGIGLSI 631
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFyrvessRNRASGGSGLGLAI 80
|
90
....*....|..
gi 446601147 632 SVSLMAQMKGDL 643
Cdd:cd16946 81 CHNIALAHGGTI 92
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
568-656 |
1.25e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 41.80 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 568 NVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPF------TTSKAVGLGIGLSISVSLMAQMKG 641
Cdd:cd16952 7 NLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFyrvdieRCRNTGGTGLGLAIVKHVMSRHDA 86
|
90
....*....|....*...
gi 446601147 642 DLRLASTL---TRNACVV 656
Cdd:cd16952 87 RLLIASELgkgSRFTCLF 104
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
365-416 |
1.56e-04 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 39.92 E-value: 1.56e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 446601147 365 RLVKRFTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRHTLGQLNMQRR 416
Cdd:smart00304 2 RLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| HAMP |
pfam00672 |
HAMP domain; |
361-412 |
1.73e-04 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 39.53 E-value: 1.73e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 446601147 361 FIRSRLVKRFTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRHTLGQLN 412
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLR 52
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
454-668 |
1.78e-04 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 44.93 E-value: 1.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 454 TLAHEINQPLNA---LS-MYLFTAgraIEQGQSGQARNTLTKAEGLINRIDAIIrSLRQFTRRaELETPLYPVDLRQtFV 529
Cdd:PRK11091 289 TISHELRTPLNGivgLSrILLDTE---LTAEQRKYLKTIHVSAITLGNIFNDII-DMDKMERR-KLQLDNQPIDFTD-FL 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 530 AAWELLAmRHQSRQGALSLPTDTV-----WVSGDEVRIQQVLVNVLANALDAcSHDAAIAVT-WQTQGEALEVYIADNGP 603
Cdd:PRK11091 363 ADLENLS-GLQAEQKGLRFDLEPLlplphKVITDGTRLRQILWNLISNAVKF-TQQGGVTVRvRYEEGDMLTFEVEDSGI 440
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446601147 604 GWPVAllpSLLKPFT----------TSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQFSVTDVDDVE 668
Cdd:PRK11091 441 GIPED---ELDKIFAmyyqvkdshgGKPATGTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIHAPAVAEEV 512
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
420-647 |
3.57e-04 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 43.95 E-value: 3.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 420 QEVAERKEIEADLRAMQDELIQTAklAVVGQTMTTLAHEINQPLNALSMYL-FTAGRAIEQGQSGQARN-TLTKAEGLIN 497
Cdd:PRK09959 686 QDITETRDLIHALEVERNKAINAT--VAKSQFLATMSHEIRTPISSIMGFLeLLSGSGLSKEQRVEAISlAYATGQSLLG 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 498 RIDAIIRSLRQFTRRAELEtPLY---PVDLRQTFVAAWELLAMRHQSRQGALSLPtDTVWVSGDEVRIQQVLVNVLANAL 574
Cdd:PRK09959 764 LIGEILDVDKIESGNYQLQ-PQWvdiPTLVQNTCHSFGAIAASKSIALSCSSTFP-DHYLVKIDPQAFKQVLSNLLSNAL 841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 575 DACSHDAAIAVTWQTQGE----ALEVYIADNGPGWPVALLPSLLKPFTTSKA----VGLGIGLSISVSLMAQMKGDLRLA 646
Cdd:PRK09959 842 KFTTEGAVKITTSLGHIDdnhaVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAgrqqTGSGLGLMICKELIKNMQGDLSLE 921
|
.
gi 446601147 647 S 647
Cdd:PRK09959 922 S 922
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
399-648 |
5.23e-04 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 42.30 E-value: 5.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 399 RIARLLRHTLGQLNMQRRQLEQEVAERKEIEADLramQDELIQTaklavvgqtmttlaheinqpLNALSMYLFTAGRAIE 478
Cdd:COG4585 28 RARRAERAAELERELAARAEEAREEERRRIAREL---HDGVGQS--------------------LSAIKLQLEAARRLLD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 479 QgQSGQARNTLTKAEGLInriDAIIRSLRQFTRRaeletpLYPVDL-RQTFVAAWELLAMRHQSRQGalsLPTdTVWVSG 557
Cdd:COG4585 85 A-DPEAAREELEEIRELA---REALAELRRLVRG------LRPPALdDLGLAAALEELAERLLRAAG---IRV-ELDVDG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 558 DEVR------------IQQVLVNVL--ANAldacshdAAIAVTWQTQGEALEVYIADNGPGwpvallpsllkpFTTSKAV 623
Cdd:COG4585 151 DPDRlppevelalyriVQEALTNALkhAGA-------TRVTVTLEVDDGELTLTVRDDGVG------------FDPEAAP 211
|
250 260
....*....|....*....|....*
gi 446601147 624 GLGIGLSISVSLMAQMKGDLRLAST 648
Cdd:COG4585 212 GGGLGLRGMRERAEALGGTLTIGSA 236
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
538-659 |
7.80e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 39.92 E-value: 7.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 538 RHQSRQGALSLPTDTVWVsGDEVRIQQVLVNVLANALDACshDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPF 617
Cdd:cd16954 15 QRKGVSISLDISPELRFP-GERNDLMELLGNLLDNACKWC--LEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQRG 91
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 446601147 618 T--TSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQF 659
Cdd:cd16954 92 QrlDEQRPGQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
568-658 |
1.39e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 38.81 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 568 NVLANALDACSH----DAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLL-KPFTTSKAVGLGIGLSISVSLMAQMKGD 642
Cdd:cd16915 7 NLIDNALDALAAtgapNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFeRGVSTKGQGERGIGLALVRQSVERLGGS 86
|
90
....*....|....*.
gi 446601147 643 LRLASTLTRNACVVLQ 658
Cdd:cd16915 87 ITVESEPGGGTTFSIR 102
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
445-511 |
1.86e-03 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 37.19 E-value: 1.86e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446601147 445 LAVVGQTMTTLAHEINQPLNALSMYLFTAGRaiEQGQSGQARNTLTKAEGLINRIDAIIRSLRQFTR 511
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEE--ELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
449-511 |
1.91e-03 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 37.19 E-value: 1.91e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446601147 449 GQTMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQARNTLTKAeglINRIDAIIRSLRQFTR 511
Cdd:pfam00512 3 SEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQREYLETILRS---AERLLRLINDLLDLSR 62
|
|
| HATPase_Phy-like |
cd16932 |
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana ... |
557-644 |
2.55e-03 |
|
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana Phytochrome A, B, C, D and E; This family includes the histidine kinase-like ATPase (HATPase) domains of plant red/far-red photoreceptors, the phytochromes, and includes the Arabidopsis thaliana phytochrome family phyA-phyE. Following red light absorption, biologically inactive forms of phytochromes convert to active forms, which rapidly convert back to inactive forms upon far-red light irradiation. Phytochromes can be considered as having an N-terminal photosensory region to which a bilin chromophore is bound, and a C-terminal output region, which includes the HATPase domain represented here, and is involved in dimerization and presumably contributes to relaying the light signal to downstream signaling events.
Pssm-ID: 340409 [Multi-domain] Cd Length: 113 Bit Score: 38.02 E-value: 2.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 557 GDEVRIQQVLVNVLANALD-ACSHDAAIAVTWQTQGEA---------LEVYIADNGPGWPVALLPSLlkpFTTSKAVGL- 625
Cdd:cd16932 2 GDQIRLQQVLADFLLNAVRfTPSPGGWVEIKVSPTKKQigdgvhvihLEFRITHPGQGLPEELVQEM---FEENQWTTQe 78
|
90
....*....|....*....
gi 446601147 626 GIGLSISVSLMAQMKGDLR 644
Cdd:cd16932 79 GLGLSISRKLVKLMNGDVR 97
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
173-514 |
3.52e-03 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 40.39 E-value: 3.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 173 QGTLLDQIEANQGDAAQYLQRSREVQNEQQQVYTLARIENQIVDDLRDRLNELKSGNNDGMLVETHIRYLENLKKTADEN 252
Cdd:COG0840 13 ALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 253 IRALDDWPSTITLRQTIDELLEIGMVKNKMPDTMRDYVAAQKALLDASRAREATLGRFRTLLEAQLGSSHQQMQTFNQRL 332
Cdd:COG0840 93 LALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAAL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 333 EQIVRVSGGLILVATLLALLLAWGLNHYFIRSRLVKRFTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRHTLGQLN 412
Cdd:COG0840 173 ALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENLR 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 413 MQRRQLEQEVAERKEIEADLRAMQDEL-----IQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQ--A 485
Cdd:COG0840 253 ELVGQVRESAEQVASASEELAASAEELaagaeEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEGGevV 332
|
330 340
....*....|....*....|....*....
gi 446601147 486 RNTLTKAEGLINRIDAIIRSLRQFTRRAE 514
Cdd:COG0840 333 EEAVEGIEEIRESVEETAETIEELGESSQ 361
|
|
| HATPase_YpdA-YehU-LytS-like |
cd16924 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
564-629 |
3.63e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli YpdA, YehU, Bacillus subtilis LytS, and some hybrid sensor histidine kinases; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. It also includes the HATPase domains of Escherichia coli YpdA and YehU, HKs of YpdA-YpdB and YehU-YehTCSs, which are involved together in a nutrient sensing regulatory network. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), some having accessory sensor domain(s) such as Cache, HAMP or GAF; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340401 [Multi-domain] Cd Length: 103 Bit Score: 37.43 E-value: 3.63e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446601147 564 QVLV-NVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKpfttSKAVGLGIGL 629
Cdd:cd16924 7 QPLVeNAIQHGLSPLTDKGVVTISALKEDNHVMIEVEDNGRGIDPKVLNILGK----KPKEGNGIGL 69
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
449-511 |
3.80e-03 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 36.39 E-value: 3.80e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446601147 449 GQTMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQARNTLTKAeglINRIDAIIRSLRQFTR 511
Cdd:smart00388 3 REFLANLSHELRTPLTAIRGYLELLLDTELSEEQREYLETILRE---AERLLRLINDLLDLSR 62
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
561-629 |
4.44e-03 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 37.59 E-value: 4.44e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446601147 561 RIQQVLVNVLANALD-ACSHDAA--IAVTWQTQGEALEVYIADNGPGWPVALLPsllKPFTTSKAVGLGIGL 629
Cdd:COG2172 34 DLVLAVSEAVTNAVRhAYGGDPDgpVEVELELDPDGLEIEVRDEGPGFDPEDLP---DPYSTLAEGGRGLFL 102
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
555-651 |
7.23e-03 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 39.45 E-value: 7.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446601147 555 VSGDEVRIQQVLVNVLANAL---DACSHDAAIAVTWQTQGEA-LEVYIADNGPGWPVALLPSLLKPFTTSKAV------G 624
Cdd:PRK11107 402 VIGDPLRLQQIITNLVGNAIkftESGNIDILVELRALSNTKVqLEVQIRDTGIGISERQQSQLFQAFRQADASisrrhgG 481
|
90 100
....*....|....*....|....*..
gi 446601147 625 LGIGLSISVSLMAQMKGDLRLASTLTR 651
Cdd:PRK11107 482 TGLGLVITQKLVNEMGGDISFHSQPNR 508
|
|
| |
