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Conserved domains on  [gi|446609386|ref|WP_000686732|]
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ferredoxin-type protein NapF [Escherichia coli]

Protein Classification

similar to ferredoxin-type protein NapF( domain architecture ID 11484607)

protein similar to ferredoxin-type protein NapF

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10194 PRK10194
ferredoxin-type protein NapF;
2-164 4.02e-110

ferredoxin-type protein NapF;


:

Pssm-ID: 182296 [Multi-domain]  Cd Length: 163  Bit Score: 310.03  E-value: 4.02e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386   2 KIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPE 81
Cdd:PRK10194   1 KIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  82 SLFSPRHTRAWDWQFTIGDACLAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEYL 161
Cdd:PRK10194  81 SLFSPRHTRAWDLQFTIGDACLAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEYL 160


                 ...
gi 446609386 162 HAH 164
Cdd:PRK10194 161 HAH 163
 
Name Accession Description Interval E-value
PRK10194 PRK10194
ferredoxin-type protein NapF;
2-164 4.02e-110

ferredoxin-type protein NapF;


Pssm-ID: 182296 [Multi-domain]  Cd Length: 163  Bit Score: 310.03  E-value: 4.02e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386   2 KIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPE 81
Cdd:PRK10194   1 KIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  82 SLFSPRHTRAWDWQFTIGDACLAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEYL 161
Cdd:PRK10194  81 SLFSPRHTRAWDLQFTIGDACLAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEYL 160


                 ...
gi 446609386 162 HAH 164
Cdd:PRK10194 161 HAH 163
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 23-157 1.02e-68

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 204.40  E-value: 1.02e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  23 RPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPESLFSPRHTRAWDWQFTIGDAC 102
Cdd:cd10564    1 RPPWAVDEALFLDLCTRCGDCVEACPEGIIVRGDGGFPELDFSRGECTFCGACAEACPEGALDPAREAPWPLRAEIGDSC 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446609386 103 LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:cd10564   81 LALQGVECRSCQDACPTQAIRFRPRLGGIALPELDADACTGCGACVSVCPVGAIT 135
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 7-102 2.10e-49

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 154.33  E-value: 2.10e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386    7 RRGILTGRWRKASNG-----IRPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPE 81
Cdd:TIGR00402   1 RRGLLRGVFPATSSTiektqIRPPWSARESLFSAVCTRCGECASACENNILQLGQQGQPTVEFDNAECDFCGKCAEACPT 80

                          90       100
                  ....*....|....*....|.
gi 446609386   82 SLFSPRHTRAWDWQFTIGDAC 102
Cdd:TIGR00402  81 NAFHPRFPGDWLLRPQISSAC 101
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 108-157 5.77e-08

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 47.42  E-value: 5.77e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 446609386 108 VECRRCQDSCEPMAIifrpTLSGIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG1149   14 IGCGLCVEVCPEGAI----KLDDGGAPVVDPDLCTGCGACVGVCPTGAIT 59
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 37-80 6.79e-04

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 35.97  E-value: 6.79e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 446609386   37 CTRCDACINACENNILQR----GAGGYPSVNFKNNECSFCYACAQACP 80
Cdd:pfam12838   1 CIGCGACVAACPVGAITLdevgEKKGTKTVVIDPERCVGCGACVAVCP 48
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 36-80 2.70e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 36.76  E-value: 2.70e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 446609386  36 HCTRCDACINAC-ENNIlqRGAGGYPSvnFKNNeCSFCYACAQACP 80
Cdd:NF038196 186 KCIGCGICAKVCpVNNI--EMEDGKPV--WGHN-CTHCLACIHRCP 226
 
Name Accession Description Interval E-value
PRK10194 PRK10194
ferredoxin-type protein NapF;
2-164 4.02e-110

ferredoxin-type protein NapF;


Pssm-ID: 182296 [Multi-domain]  Cd Length: 163  Bit Score: 310.03  E-value: 4.02e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386   2 KIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPE 81
Cdd:PRK10194   1 KIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  82 SLFSPRHTRAWDWQFTIGDACLAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEYL 161
Cdd:PRK10194  81 SLFSPRHTRAWDLQFTIGDACLAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEYL 160


                 ...
gi 446609386 162 HAH 164
Cdd:PRK10194 161 HAH 163
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 23-157 1.02e-68

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 204.40  E-value: 1.02e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  23 RPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPESLFSPRHTRAWDWQFTIGDAC 102
Cdd:cd10564    1 RPPWAVDEALFLDLCTRCGDCVEACPEGIIVRGDGGFPELDFSRGECTFCGACAEACPEGALDPAREAPWPLRAEIGDSC 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446609386 103 LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:cd10564   81 LALQGVECRSCQDACPTQAIRFRPRLGGIALPELDADACTGCGACVSVCPVGAIT 135
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 7-102 2.10e-49

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 154.33  E-value: 2.10e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386    7 RRGILTGRWRKASNG-----IRPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPE 81
Cdd:TIGR00402   1 RRGLLRGVFPATSSTiektqIRPPWSARESLFSAVCTRCGECASACENNILQLGQQGQPTVEFDNAECDFCGKCAEACPT 80

                          90       100
                  ....*....|....*....|.
gi 446609386   82 SLFSPRHTRAWDWQFTIGDAC 102
Cdd:TIGR00402  81 NAFHPRFPGDWLLRPQISSAC 101
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 22-158 2.64e-23

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 89.62  E-value: 2.64e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  22 IRPPWSGDESHFLTHCTRCDACINACENNILQRG-------AGGYPSVNFKNNECSFCY-ACAQACPESLFSPRHTRAWD 93
Cdd:cd16373    1 LRPPGALDEEEFLALCIRCGLCVEACPTGVIQPAgledgleGGRTPYLDPREGPCDLCCdACVEVCPTGALRPLDLEEQK 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446609386  94 WQftIG------DACLAYQS-VECRRCQDSCEPMAIIFRPtLSGIYQPQLNSQLCNGCGACAASCPVSAITA 158
Cdd:cd16373   81 VK--MGvavidkDRCLAWQGgTDCGVCVEACPTEAIAIVL-EDDVLRPVVDEDKCVGCGLCEYVCPVEPPKA 149
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 37-156 1.42e-10

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 55.87  E-value: 1.42e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  37 CTRCDACINACENNILQRGAGGYPSVNFKNNE--CSFCYACAQACPESL--FSPRHTRAWDW--QFTIGDACLayqsVEC 110
Cdd:cd10549    8 CIGCGICVKACPTDAIELGPNGAIARGPEIDEdkCVFCGACVEVCPTGAieLTPEGKEYVPKekEAEIDEEKC----IGC 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 446609386 111 RRCQDSCEPMAIifrpTLSGIYQPQLNSQLCNGCGACAASCPVSAI 156
Cdd:cd10549   84 GLCVKVCPVDAI----TLEDELEIVIDKEKCIGCGICAEVCPVNAI 125
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 108-157 5.77e-08

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 47.42  E-value: 5.77e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 446609386 108 VECRRCQDSCEPMAIifrpTLSGIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG1149   14 IGCGLCVEVCPEGAI----KLDDGGAPVVDPDLCTGCGACVGVCPTGAIT 59
napG PRK09476
quinol dehydrogenase periplasmic component; Provisional
 22-151 8.15e-08

quinol dehydrogenase periplasmic component; Provisional


Pssm-ID: 236534 [Multi-domain]  Cd Length: 254  Bit Score: 50.01  E-value: 8.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  22 IRPPWSGDESHFLTHCTRCDACINACENNILQRG------AGGYPSVNFKNNECSFC--YACAQACPeslfsprhTRAWD 93
Cdd:PRK09476  46 LRPPGALNENDFLSACIRCGLCVQACPYDTLKLAtlasglSAGTPYFVARDIPCEMCedIPCVKACP--------SGALD 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  94 WQFT-IGDA------------CLAYQSVECRRCQDSCePM---AIIF---RPTLSGIYQ---PQLNSQLCNGCGACAASC 151
Cdd:PRK09476 118 RELVdIDDArmglavlvdqenCLNFQGLRCDVCYRVC-PLidkAITLeleRNERTGKHAfflPTVHSDACTGCGKCEKAC 196
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
110-157 1.05e-06

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 47.16  E-value: 1.05e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 446609386 110 CRRCQDSCEPMAIIFRPtlsgIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG1148  501 CGRCVEVCPYGAISIDE----KGVAEVNPALCKGCGTCAAACPSGAIS 544
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 37-81 1.11e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 43.93  E-value: 1.11e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 446609386  37 CTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACPE 81
Cdd:COG1146   10 CIGCGACVEVCPVDVLELDEEGKKALVINPEECIGCGACELVCPV 54
NapF COG1145
Ferredoxin [Energy production and conversion];
37-81 1.34e-05

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 43.56  E-value: 1.34e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 446609386  37 CTRCDACINACENNILQRGAGGyPSVNFKNNECSFCYACAQACPE 81
Cdd:COG1145  184 CIGCGLCVKVCPTGAIRLKDGK-PQIVVDPDKCIGCGACVKVCPV 227
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 68-156 1.35e-05

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 44.25  E-value: 1.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  68 ECSFCYACAQACPESlfspRHTRAWDWQFT-------IGDACLAYQSVECRRCQD-----SCEPMAIIFRPTlsgiyQPQ 135
Cdd:PRK12809  11 ECIGCHACEIACAVA----HNQENWPLSHSdfrprihVVGKGQAANPVACHHCNNapcvtACPVNALTFQSD-----SVQ 81

                         90       100
                 ....*....|....*....|.
gi 446609386 136 LNSQLCNGCGACAASCPVSAI 156
Cdd:PRK12809  82 LDEQKCIGCKRCAIACPFGVV 102
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
69-157 2.98e-05

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 41.57  E-value: 2.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  69 CSFCYACAQACPESLFSPRHTRAWDWQFTIGDAcLAYQSVECRRCQD-----SCEPMAIIFRPTlsgiyQPQLNSQLCNG 143
Cdd:COG1142   12 CIGCRTCEAACAVAHEGEEGEPFLPRIRVVRKA-GVSAPVQCRHCEDapcaeVCPVGAITRDDG-----AVVVDEEKCIG 85

                         90
                 ....*....|....
gi 446609386 144 CGACAASCPVSAIT 157
Cdd:COG1142   86 CGLCVLACPFGAIT 99
NapF COG1145
Ferredoxin [Energy production and conversion];
110-157 3.48e-05

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 42.40  E-value: 3.48e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 446609386 110 CRRCQDSCEPMAIIFRPtlsGIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG1145  187 CGLCVKVCPTGAIRLKD---GKPQIVVDPDKCIGCGACVKVCPVGAIS 231
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 110-159 3.74e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 40.03  E-value: 3.74e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 446609386 110 CRRCQDSCEPMAIIFRPTLSGIyqpqlNSQLCNGCGACAASCPVSAITAE 159
Cdd:COG4231   27 CGACVKVCPADAIEEGDGKAVI-----DPDLCIGCGSCVQVCPVDAIKLE 71
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 37-81 8.74e-05

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 38.94  E-value: 8.74e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 446609386  37 CTRCDACINACENNILQRGAGGYPSVNfkNNECSFCYACAQACPE 81
Cdd:COG1149   13 CIGCGLCVEVCPEGAIKLDDGGAPVVD--PDLCTGCGACVGVCPT 55
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 108-157 1.14e-04

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 38.88  E-value: 1.14e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 446609386 108 VECRRCQDSCEPMAIIFRPtlsgIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG1144   33 IGCGLCWIVCPDGAIRVDD----GKYYGIDYDYCKGCGICAEVCPVKAIE 78
FDH-O_like cd10560
beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes ...
 100-164 1.70e-04

beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.


Pssm-ID: 319882 [Multi-domain]  Cd Length: 225  Bit Score: 40.45  E-value: 1.70e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446609386 100 DACLayqsvECRR--CQDSCePMAIIFRPTLSGIYqpqLNSQLCNGCGACAASCP--VSAITAEYLHAH 164
Cdd:cd10560   76 DVCK-----HCTDagCLEAC-PTGAIFRTEFGTVY---IQPDICNGCGYCVAACPfgVIDRNEETGRAH 135
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 133-160 1.94e-04

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 40.02  E-value: 1.94e-04
                         10        20
                 ....*....|....*....|....*...
gi 446609386 133 QPQLNSQLCNGCGACAASCPVSAITAEY 160
Cdd:PRK12387  32 KPEYNPQQCIGCAACVNACPSNALTVET 59
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
36-157 3.15e-04

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 40.01  E-value: 3.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  36 HCTRCDACINACENNILQRGAGGYpsvnfknneCSFCYACAQACPESLFSPRHTRAwdwqFTIGDAClayqsVECRRCQD 115
Cdd:COG4624   40 EHVDDDSACSCCPRCCLCCCCCCR---------CCVAISCIQVRGIIIIDKRGPSI----IRDKEKC-----KNCYPCVR 101

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446609386 116 SCEPMAIIFRPTlsgiyQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG4624  102 ACPVKAIKVDDG-----KAEIDEEKCISCGQCVAVCPFGAIT 138
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 109-157 3.87e-04

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 39.29  E-value: 3.87e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 446609386 109 ECRRCQDSCEPMAIIFRPTLSGIyqpqlNSQLCNGCGACAASCPVSAIT 157
Cdd:cd03110   68 RCGNCERVCKFGAILEFFQKLIV-----DESLCEGCGACVIICPRGAIY 111
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 108-159 5.48e-04

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 36.57  E-value: 5.48e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446609386 108 VECRRCQDSCEPMAIifrpTLSGiYQPQLNSQLCNGCGACAASCPVSAITAE 159
Cdd:COG2221   18 IGCGLCVAVCPTGAI----SLDD-GKLVIDEEKCIGCGACIRVCPTGAIKGE 64
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 37-80 6.79e-04

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 35.97  E-value: 6.79e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 446609386   37 CTRCDACINACENNILQR----GAGGYPSVNFKNNECSFCYACAQACP 80
Cdd:pfam12838   1 CIGCGACVAACPVGAITLdevgEKKGTKTVVIDPERCVGCGACVAVCP 48
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 32-157 7.05e-04

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 37.75  E-value: 7.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  32 HFLTHCTRCDACINACENNILQRGAGGYPSV----------NFKNNECSFCY--ACAQACPESLFSPRHTRA--WDWQFT 97
Cdd:cd04410    3 VDLDRCIGCGTCEVACKQEHGLRPGPDWSRIkvieggglerAFLPVSCMHCEdpPCVKACPTGAIYKDEDGIvlIDEDKC 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446609386  98 IGdaclayqsveCRRCQDSCePMAIIFRPTLSGIyqpqlnSQLCNGCG---------ACAASCPVSAIT 157
Cdd:cd04410   83 IG----------CGSCVEAC-PYGAIVFDPEPGK------AVKCDLCGdrldeglepACVKACPTGALT 134
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 110-157 7.18e-04

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 36.26  E-value: 7.18e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 446609386 110 CRRCQDSCePMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG1143    7 CGLCVRVC-PVDAITIEDGEPGKVYVIDPDKCIGCGLCVEVCPTGAIS 53
PRK13795 PRK13795
hypothetical protein; Provisional
 37-80 7.18e-04

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 38.82  E-value: 7.18e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 446609386  37 CTRCDACINACENNILQRGAGGyPSVNFKNNECSFCYACAQACP 80
Cdd:PRK13795 583 CVGCGVCVGACPTGAIRIEEGK-RKISVDEEKCIHCGKCTEVCP 625
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 130-157 8.86e-04

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 36.18  E-value: 8.86e-04
                         10        20
                 ....*....|....*....|....*...
gi 446609386 130 GIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG2221    6 GTWPPKIDEEKCIGCGLCVAVCPTGAIS 33
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 32-81 1.06e-03

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 37.94  E-value: 1.06e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446609386  32 HFLTHCTRCDACINACENNILQRGAGgypSVNFKNNE-CSFCYACAQACPE 81
Cdd:PRK00783 166 EVSEDCDECEKCVEACPRGVLELKEG---KLVVTDLLnCSLCKLCERACPG 213
Fer4_9 pfam13187
4Fe-4S dicluster domain;
37-80 1.40e-03

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 35.22  E-value: 1.40e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 446609386   37 CTRCDACINACENNILQRGAGGYP-SVNFKNNECSFCYACAQACP 80
Cdd:pfam13187   2 CTGCGACVAACPAGAIVPDLVGQTiRGDIAGLACIGCGACVDACP 46
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 66-156 1.44e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 36.87  E-value: 1.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  66 NNECSFCYACAQACpeslfsprhTRAWDWQFTIGDACLAYQS----------VECRRCQD-----SCEPMAIIFRPTlsg 130
Cdd:cd16370    8 MERCIGCYSCMLAC---------SRRVHKSASLSKSAIRVRTrggleggftvVVCRACEDppcaeACPTGALEPRKG--- 75

                         90       100
                 ....*....|....*....|....*.
gi 446609386 131 iYQPQLNSQLCNGCGACAASCPVSAI 156
Cdd:cd16370   76 -GGVVLDKEKCIGCGNCVKACIVGAI 100
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 110-159 1.86e-03

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 35.07  E-value: 1.86e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 446609386 110 CRRCQDSCEpmAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAE 159
Cdd:COG1146   13 CGACVEVCP--VDVLELDEEGKKALVINPEECIGCGACELVCPVGAITVE 60
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
108-157 2.32e-03

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 36.96  E-value: 2.32e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 446609386 108 VECRRCQDSCePMAIIfrptlsgIYQPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG0348  213 IDCGLCVKVC-PMGID-------IRKGEINQSECINCGRCIDACPKDAIR 254
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 36-80 2.70e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 36.76  E-value: 2.70e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 446609386  36 HCTRCDACINAC-ENNIlqRGAGGYPSvnFKNNeCSFCYACAQACP 80
Cdd:NF038196 186 KCIGCGICAKVCpVNNI--EMEDGKPV--WGHN-CTHCLACIHRCP 226
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
37-81 6.02e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 36.38  E-value: 6.02e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 446609386  37 CTRCDACINACENNILQRGAGGYPSVNfkNNECSFCYACAQACPE 81
Cdd:COG1148  498 CTGCGRCVEVCPYGAISIDEKGVAEVN--PALCKGCGTCAAACPS 540
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 108-155 7.12e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 33.27  E-value: 7.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 446609386  108 VECRRCQDSCEPMAIIFRPTL--SGIYQPQLNSQLCNGCGACAASCPVSA 155
Cdd:pfam12838   2 IGCGACVAACPVGAITLDEVGekKGTKTVVIDPERCVGCGACVAVCPTGA 51
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
127-157 7.13e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 35.99  E-value: 7.13e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 446609386 127 TLSGIYqPQLNSQLCNGCGACAASCPVSAIT 157
Cdd:COG1148  485 GVEPSV-AEVDPEKCTGCGRCVEVCPYGAIS 514
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 36-157 7.32e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 35.74  E-value: 7.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446609386  36 HCTRCDACINACENNILQRGAGGYPSVNfkNNECSFCYACAQACPESLFS------PRHTRAWDWQFTigdaclAYQSVE 109
Cdd:COG2878  138 GCIGCGDCIKACPFDAIVGAAKGMHTVD--EDKCTGCGLCVEACPVDCIEmvpvspTVVVSSWDKGKA------VRKVVG 209

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 446609386 110 C-RRCQDSCEPMAIIFRPTLSGIYQPqlnsQLCNGCGACAASCPVSAIT 157
Cdd:COG2878  210 CiGLCCKKCCPAAAITVNNLAAIIDY----KKCTCCGCCEKCCPTAIIA 254
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
108-159 7.51e-03

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 33.55  E-value: 7.51e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446609386 108 VECRRCQDSCEPMAIIFRptlSGIYQpqLNSQLCNGCGACAASCPVSAITAE 159
Cdd:COG2768   14 IGCGACVKVCPVGAISIE---DGKAV--IDPEKCIGCGACIEVCPVGAIKIE 60
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 37-81 7.78e-03

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 33.87  E-value: 7.78e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 446609386  37 CTRCDACINACENNILQRGAGGYPSVNFknNECSFCYACAQACPE 81
Cdd:COG1144   32 CIGCGLCWIVCPDGAIRVDDGKYYGIDY--DYCKGCGICAEVCPV 74
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 130-159 9.12e-03

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 33.16  E-value: 9.12e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 446609386 130 GIYQPQLNSQLCNGCGACAASCPVSAITAE 159
Cdd:COG1149    2 KRKIPVIDEEKCIGCGLCVEVCPEGAIKLD 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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