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Conserved domains on  [gi|446618337|ref|WP_000695683|]
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MULTISPECIES: DUF305 domain-containing protein [Enterobacteriaceae]

Protein Classification

DUF305 domain-containing protein( domain architecture ID 10007543)

DUF305 domain-containing protein similar to Synechocystis sp. CopM, a protein that binds copper and contributes to copper resistance in Synechocystis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3544 COG3544
Uncharacterized conserved protein, DUF305 family [Function unknown];
43-113 9.38e-24

Uncharacterized conserved protein, DUF305 family [Function unknown];


:

Pssm-ID: 442765  Cd Length: 75  Bit Score: 86.50  E-value: 9.38e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446618337  43 MNEMHEKMMAAVKEPDPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAEDIIKAQKGEIDQMNKWLD 113
Cdd:COG3544    1 MIPHHQQAVEMASGADFDRLFLQLMIAHHQGAIDMAQAELEHGKDPEVRELAQDIIAAQTAEIAQMRALLA 71
 
Name Accession Description Interval E-value
COG3544 COG3544
Uncharacterized conserved protein, DUF305 family [Function unknown];
43-113 9.38e-24

Uncharacterized conserved protein, DUF305 family [Function unknown];


Pssm-ID: 442765  Cd Length: 75  Bit Score: 86.50  E-value: 9.38e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446618337  43 MNEMHEKMMAAVKEPDPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAEDIIKAQKGEIDQMNKWLD 113
Cdd:COG3544    1 MIPHHQQAVEMASGADFDRLFLQLMIAHHQGAIDMAQAELEHGKDPEVRELAQDIIAAQTAEIAQMRALLA 71
DUF305 pfam03713
Domain of unknown function (DUF305); Domain found in small family of bacterial secreted ...
 16-112 1.82e-21

Domain of unknown function (DUF305); Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.


Pssm-ID: 427457 [Multi-domain]  Cd Length: 151  Bit Score: 83.13  E-value: 1.82e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446618337   16 PAISAEHSDMKMGDMGSSAssqayMSGM-NEMHEKMMAAVKEPDPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLA 94
Cdd:pfam03713  59 PPSSAGGHAHGGGGAEGAG-----MPGMaSPADLAALRAATGADFDRLFLELMIPHHQGAVEMAQDELDRGTDPEVRALA 133

                          90
                  ....*....|....*...
gi 446618337   95 EDIIKAQKGEIDQMNKWL 112
Cdd:pfam03713 134 QDIIESQQAEIAQMRQLL 151
 
Name Accession Description Interval E-value
COG3544 COG3544
Uncharacterized conserved protein, DUF305 family [Function unknown];
43-113 9.38e-24

Uncharacterized conserved protein, DUF305 family [Function unknown];


Pssm-ID: 442765  Cd Length: 75  Bit Score: 86.50  E-value: 9.38e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446618337  43 MNEMHEKMMAAVKEPDPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAEDIIKAQKGEIDQMNKWLD 113
Cdd:COG3544    1 MIPHHQQAVEMASGADFDRLFLQLMIAHHQGAIDMAQAELEHGKDPEVRELAQDIIAAQTAEIAQMRALLA 71
DUF305 pfam03713
Domain of unknown function (DUF305); Domain found in small family of bacterial secreted ...
 16-112 1.82e-21

Domain of unknown function (DUF305); Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.


Pssm-ID: 427457 [Multi-domain]  Cd Length: 151  Bit Score: 83.13  E-value: 1.82e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446618337   16 PAISAEHSDMKMGDMGSSAssqayMSGM-NEMHEKMMAAVKEPDPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLA 94
Cdd:pfam03713  59 PPSSAGGHAHGGGGAEGAG-----MPGMaSPADLAALRAATGADFDRLFLELMIPHHQGAVEMAQDELDRGTDPEVRALA 133

                          90
                  ....*....|....*...
gi 446618337   95 EDIIKAQKGEIDQMNKWL 112
Cdd:pfam03713 134 QDIIESQQAEIAQMRQLL 151
DUF305 pfam03713
Domain of unknown function (DUF305); Domain found in small family of bacterial secreted ...
 60-113 2.30e-16

Domain of unknown function (DUF305); Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.


Pssm-ID: 427457 [Multi-domain]  Cd Length: 151  Bit Score: 70.04  E-value: 2.30e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 446618337   60 DKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAEDIIKAQKGEIDQMNKWLD 113
Cdd:pfam03713   1 DVGFAQDMIPHHQQAVEMAELALERAQDPEVRALAQDIIAAQQPEIGQMRGWLE 54
COG3652 COG3652
Predicted outer membrane protein, contains DUF4142 domain [Function unknown];
43-100 1.47e-03

Predicted outer membrane protein, contains DUF4142 domain [Function unknown];


Pssm-ID: 442869  Cd Length: 176  Bit Score: 36.07  E-value: 1.47e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446618337  43 MNEMHEKMMA---AVKEPDPDKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAEDIIKA 100
Cdd:COG3652   99 LSADQQAKLDklsKLSGAAFDKAYVDQQVAAHEKAVALFEKYAAPGKDAELKAFAQKTLPT 159
DUF4142 pfam13628
Domain of unknown function (DUF4142); This is a bacterial family of unknown function.
 43-96 2.13e-03

Domain of unknown function (DUF4142); This is a bacterial family of unknown function.


Pssm-ID: 433361  Cd Length: 138  Bit Score: 35.29  E-value: 2.13e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 446618337   43 MNEMHEKMMAAVKEPDP---DKAFAKGMIAHHEGAIAMAETELKYGKDPEMRKLAED 96
Cdd:pfam13628  67 LDADQQAKLDKLSALSGaafDKAYLDQQVAAHQKAVELFEKYAASGDDPELKAFAAK 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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