NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|446625751|ref|WP_000703097|]
View 

MULTISPECIES: phosphoglycerate mutase [Bacillus]

Protein Classification

histidine phosphatase family protein( domain architecture ID 1903463)

histidine phosphatase family protein is a probable phosphatase that may catalyze the dephosphorylation of a phosphorylated substrate involving a conserved catalytic histidine residue which becomes phosphorylated during the reaction

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PhoE super family cl43133
Broad specificity phosphatase PhoE [Carbohydrate transport and metabolism];
55-188 4.57e-04

Broad specificity phosphatase PhoE [Carbohydrate transport and metabolism];


The actual alignment was detected with superfamily member COG0406:

Pssm-ID: 440175 [Multi-domain]  Cd Length: 195  Bit Score: 39.54  E-value: 4.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446625751  55 VLTSDQRRAVQSAAELTD--SLSFMQNSLFRE-----------AEVPSCFfaPKWLKctikvwmfigrtLWILGYHK--- 118
Cdd:COG0406   51 VYSSPLQRARQTAEALAEalGLPVEVDPRLREidfgdwegltfAELEARY--PEALA------------AWLADPAEfrp 116

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446625751 119 -DVESYKEVRERVRQA-AYLLHRYAlvHGSIALVGHNYVNVMIGAELRAMGWSGSPILHREPWGCTTYTFHE 188
Cdd:COG0406  117 pGGESLADVQARVRAAlEELLARHP--GGTVLVVTHGGVIRALLAHLLGLPLEAFWRLRIDNASVTVLEFDD 186
 
Name Accession Description Interval E-value
PhoE COG0406
Broad specificity phosphatase PhoE [Carbohydrate transport and metabolism];
55-188 4.57e-04

Broad specificity phosphatase PhoE [Carbohydrate transport and metabolism];


Pssm-ID: 440175 [Multi-domain]  Cd Length: 195  Bit Score: 39.54  E-value: 4.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446625751  55 VLTSDQRRAVQSAAELTD--SLSFMQNSLFRE-----------AEVPSCFfaPKWLKctikvwmfigrtLWILGYHK--- 118
Cdd:COG0406   51 VYSSPLQRARQTAEALAEalGLPVEVDPRLREidfgdwegltfAELEARY--PEALA------------AWLADPAEfrp 116

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446625751 119 -DVESYKEVRERVRQA-AYLLHRYAlvHGSIALVGHNYVNVMIGAELRAMGWSGSPILHREPWGCTTYTFHE 188
Cdd:COG0406  117 pGGESLADVQARVRAAlEELLARHP--GGTVLVVTHGGVIRALLAHLLGLPLEAFWRLRIDNASVTVLEFDD 186
 
Name Accession Description Interval E-value
PhoE COG0406
Broad specificity phosphatase PhoE [Carbohydrate transport and metabolism];
55-188 4.57e-04

Broad specificity phosphatase PhoE [Carbohydrate transport and metabolism];


Pssm-ID: 440175 [Multi-domain]  Cd Length: 195  Bit Score: 39.54  E-value: 4.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446625751  55 VLTSDQRRAVQSAAELTD--SLSFMQNSLFRE-----------AEVPSCFfaPKWLKctikvwmfigrtLWILGYHK--- 118
Cdd:COG0406   51 VYSSPLQRARQTAEALAEalGLPVEVDPRLREidfgdwegltfAELEARY--PEALA------------AWLADPAEfrp 116

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446625751 119 -DVESYKEVRERVRQA-AYLLHRYAlvHGSIALVGHNYVNVMIGAELRAMGWSGSPILHREPWGCTTYTFHE 188
Cdd:COG0406  117 pGGESLADVQARVRAAlEELLARHP--GGTVLVVTHGGVIRALLAHLLGLPLEAFWRLRIDNASVTVLEFDD 186
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH