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Conserved domains on  [gi|446632696|ref|WP_000710042|]
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MULTISPECIES: peptidylprolyl isomerase PrsA [Bacillus]

Protein Classification

peptidylprolyl isomerase( domain architecture ID 11479878)

peptidylprolyl isomerase (PPIase) accelerates the folding of proteins; it catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

CATH:  3.10.50.40
EC:  5.2.1.8
Gene Ontology:  GO:0003755|GO:0006457
PubMed:  12871165
SCOP:  3000622

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
prsA PRK03095
peptidylprolyl isomerase PrsA;
1-288 9.48e-146

peptidylprolyl isomerase PrsA;


:

Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 410.54  E-value: 9.48e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696   1 MKKAMLALAATSVIALSACGTgSSSDKIVTSKAGDITKDEFYNQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKFDE 80
Cdd:PRK03095   1 MKKAMLALAATSVIALSACGT-SSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKYDE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  81 MKKQYGDQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEKTITDKELKDNYKPEVKASHILVKDEATAKKVKEELGQGKSF 160
Cdd:PRK03095  80 MKKQYGDQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEKTITDKELKDNYKPEIKASHILVKDEATAKKVKEELGQGKSF 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 161 EELAKQYSEDTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKKDEVSEPVKTQFGYHIIKVTDIKEPEKSFEQSKADIKKEV 240
Cdd:PRK03095 160 EELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVTDIKEPEKSFEQSKADIKKEL 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 446632696 241 VQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKTDAKKEDKK 288
Cdd:PRK03095 240 VQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADAKKEEKK 287
 
Name Accession Description Interval E-value
prsA PRK03095
peptidylprolyl isomerase PrsA;
1-288 9.48e-146

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 410.54  E-value: 9.48e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696   1 MKKAMLALAATSVIALSACGTgSSSDKIVTSKAGDITKDEFYNQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKFDE 80
Cdd:PRK03095   1 MKKAMLALAATSVIALSACGT-SSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKYDE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  81 MKKQYGDQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEKTITDKELKDNYKPEVKASHILVKDEATAKKVKEELGQGKSF 160
Cdd:PRK03095  80 MKKQYGDQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEKTITDKELKDNYKPEIKASHILVKDEATAKKVKEELGQGKSF 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 161 EELAKQYSEDTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKKDEVSEPVKTQFGYHIIKVTDIKEPEKSFEQSKADIKKEV 240
Cdd:PRK03095 160 EELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVTDIKEPEKSFEQSKADIKKEL 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 446632696 241 VQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKTDAKKEDKK 288
Cdd:PRK03095 240 VQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADAKKEEKK 287
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 131-247 8.34e-43

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 143.56  E-value: 8.34e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 131 KPEVKASHILV---------KDEATAKKVKEELGQGKSFEELAKQYSEDTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKK 201
Cdd:COG0760    6 PEEVRASHILVkvppsedraKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALKP 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 446632696 202 DEVSEPVKTQFGYHIIKVTDIKEPE-KSFEQSKADIKKEVVQKKAQD 247
Cdd:COG0760   86 GEISGPVKTQFGYHIIKVEDRRPAEtPPFEEVKQQIRQELFQQALEA 132
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 138-221 3.17e-28

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 104.30  E-value: 3.17e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  138 HILVK-DEAT----------AKKVKEELGQGK-SFEELAKQYSEDTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKKDEVS 205
Cdd:pfam00639   1 HILIKtPEASerdraeakakAEEILEQLKSGEdSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKPGEIS 80

                          90
                  ....*....|....*.
gi 446632696  206 EPVKTQFGYHIIKVTD 221
Cdd:pfam00639  81 GPVETRFGFHIIKLTD 96
 
Name Accession Description Interval E-value
prsA PRK03095
peptidylprolyl isomerase PrsA;
1-288 9.48e-146

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 410.54  E-value: 9.48e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696   1 MKKAMLALAATSVIALSACGTgSSSDKIVTSKAGDITKDEFYNQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKFDE 80
Cdd:PRK03095   1 MKKAMLALAATSVIALSACGT-SSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKYDE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  81 MKKQYGDQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEKTITDKELKDNYKPEVKASHILVKDEATAKKVKEELGQGKSF 160
Cdd:PRK03095  80 MKKQYGDQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEKTITDKELKDNYKPEIKASHILVKDEATAKKVKEELGQGKSF 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 161 EELAKQYSEDTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKKDEVSEPVKTQFGYHIIKVTDIKEPEKSFEQSKADIKKEV 240
Cdd:PRK03095 160 EELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVTDIKEPEKSFEQSKADIKKEL 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 446632696 241 VQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKTDAKKEDKK 288
Cdd:PRK03095 240 VQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADAKKEEKK 287
prsA PRK03002
peptidylprolyl isomerase PrsA;
2-275 7.77e-74

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 227.90  E-value: 7.77e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696   2 KKAMLALAATSVIALSACGTGSSSDKIVTSKAGDITKDEFYNQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKFDEM 81
Cdd:PRK03002   4 KHIFIITALISILMLSACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEVQKA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  82 KKQYGDQFDTLLKQQGIK-EETLKTGVRAQLAQEKAIEKTITDKELKDNYKPEVKASHILVKDEATAKKVKEELGQGKSF 160
Cdd:PRK03002  84 KSQYGDQFKNVLKNNGLKdEADFKNQIKFKLAMNEAIKKSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAGASF 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 161 EELAKQYSEDTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKKDEVSEPVKTQFGYHIIKVTDIKEpEKSFEQSKADIKKEV 240
Cdd:PRK03002 164 EELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKD-LKPYDEVKDSIRKNL 242

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 446632696 241 VQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLF 275
Cdd:PRK03002 243 EEERTADPIFGKKLLQSELKKANIKINDSELEDTF 277
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 13-277 3.59e-73

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 226.01  E-value: 3.59e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  13 VIALSACGtgsSSDKIVTSKAGDITKDEFYNQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKFDEMKKQYGDQFDTL 92
Cdd:PRK02998  16 VLALSACG---SSDNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKYKVSDEEAKKQVEEAKDKMGDNFKST 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  93 LKQQGIK-EETLKTGVRAQLAQEKAIEKTITDKELKDNYKPEVKASHILVKDEATAKKVKEELGQGKSFEELAKQYSEDT 171
Cdd:PRK02998  93 LEQVGLKnEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNNGEDFAALAKQYSEDT 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 172 GSKEKGGDLGFFEHGKMVKEFEDAAYKLKKDEVSEPVKTQFGYHIIKVTDIKEpEKSFEQSKADIKKEVVQKKAQD--GE 249
Cdd:PRK02998 173 GSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKE-LKPFDEVKDSIRKDLEQQRLQDttGK 251

                        250       260
                 ....*....|....*....|....*...
gi 446632696 250 FMNDLMMKEIKKADVKVDDKDLKDLFEE 277
Cdd:PRK02998 252 WKQQVVNDLLKDADIKVNDKEFKDTFKF 279
prsA PRK04405
peptidylprolyl isomerase; Provisional
 1-284 3.68e-64

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 203.48  E-value: 3.68e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696   1 MKKAMLALAATSVIALSACGTGSSSDKIVTSKAGDITKDEFYNQMK-TQAGKQVLNNMVMEKVLIKNY--KVEDKEVDKK 77
Cdd:PRK04405   4 KMKKWALAAASAGLALSLAGCSSNQATVATYSGGKITQSQYYKEMKqSSAGKTVLANMIIYRALEKQYgkKVSTKKVDKQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  78 FDEMKKQYGDQFDTLLKQQGIKEETLKTGVRAQLAQEKAIE--KTITDKELKD---NYKPEVKASHILVKDEATAKKVKE 152
Cdd:PRK04405  84 YNSYKKQYGSSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKklKKVTNSQLKKawkSYQPKVTVQHILVSKKSTAETVIK 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 153 ELGQGKSFEELAKQYSEDTGSKEKGGDLGFFE--HGKMVKEFEDAAYKLKKDEV-SEPVKTQFGYHIIKVtdIKEPEK-S 228
Cdd:PRK04405 164 KLKDGKDFAKLAKKYSTDTATKNKGGKLSAFDstDTTLDSTFKTAAFKLKNGEYtTTPVKTTYGYEVIKM--IKHPAKgT 241

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446632696 229 FEQSKADIKKEVVQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKTDAKK 284
Cdd:PRK04405 242 FSDHKKALTKQIYAKWASDSSVMQRVISKVLKKANVSIKDKDLKDALSSYLSSSSS 297
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 131-247 8.34e-43

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 143.56  E-value: 8.34e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 131 KPEVKASHILV---------KDEATAKKVKEELGQGKSFEELAKQYSEDTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKK 201
Cdd:COG0760    6 PEEVRASHILVkvppsedraKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALKP 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 446632696 202 DEVSEPVKTQFGYHIIKVTDIKEPE-KSFEQSKADIKKEVVQKKAQD 247
Cdd:COG0760   86 GEISGPVKTQFGYHIIKVEDRRPAEtPPFEEVKQQIRQELFQQALEA 132
prsA PRK00059
peptidylprolyl isomerase; Provisional
 48-271 1.98e-38

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 137.92  E-value: 1.98e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  48 QAGKQVLNNMVMEKVLIKNYKVE---------DKEVDKKFDEMKKQY---GDQFDTLLKQQGIKEETLKTGVRAQLAQEK 115
Cdd:PRK00059  84 QQKEQILDSLITEKVLLQKAKELklipseeelNKEVDKKINEIKKQFnndEEQFEEALKATGFTEETFKEYLKNQIIIEK 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 116 AIEKT-----ITDKELKDNY----------KPEVKASHILVKDEATAKKVKEELGQGKSFEELAKQYSEDTGSKEKGGDL 180
Cdd:PRK00059 164 VINEVvkdvkVTDKDAQKYYnenkskftekPNTMHLAHILVKTEDEAKKVKKRLDKGEDFAKVAKEVSQDPGSKDKGGDL 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 181 GF--FEHGKMVKEFEDAAYKLKKDEVSEPVKTQFGYHIIKVTDIKE-PEKSFEQSKADIKKEVVQKKaqDGEFMNDLMMK 257
Cdd:PRK00059 244 GDvpYSDSGYDKEFMDGAKALKEGEISAPVKTQFGYHIIKAIKKKEyPVKPFDSVKEDIKKQLLQEK--QSEVFKKKIEE 321

                        250
                 ....*....|....
gi 446632696 258 EIKKADVKVDDKDL 271
Cdd:PRK00059 322 WKKALKVKKYEKNL 335
prsA PRK01326
foldase protein PrsA; Reviewed
 1-275 7.34e-38

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 135.71  E-value: 7.34e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696   1 MKKAMLALAAT--SVIALSACGTGSSSDKIVTSKAGDITKDEFYNQMK-TQAGKQVLNNMVMEKVLIKNY--KVEDKEVD 75
Cdd:PRK01326   1 MKKKLIAGAVTllSVATLAACSKTNENTKVISMKGDTITVSDFYNQVKnNPSAQQAMLNLTISRVFEKQYgdKVSDKEVE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  76 KKFDEMKKQYGDQFDTLLKQQGIKEETLKTGVRA----QLAQEKAIEKTITDKELK---DNYKPEVKASHILVKDEATAK 148
Cdd:PRK01326  81 KAYAKTAKQYGASFSRALAQAGLTPETYKAQIRTsklvEYAVKEAAKKELTDEAYKkayEEYTPEVTAQIIRLDNEDKAK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 149 KVKEEL-GQGKSFEELAKqysEDTGSKEKGGDLGFFEHGKMV-KEFEDAAYKLKKDEVSEPVKT------QFGYHIIKVT 220
Cdd:PRK01326 161 SVLEEAkAEGADFAQIAK---ENTTTKEKKGEYKFDSGSTNVpEQVKKAAFALDEDGVSDVISVldptayQSKYYIVKVT 237

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446632696 221 DIKEPEKSFEQSKADIKKEVVQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLF 275
Cdd:PRK01326 238 KKTEKKSDWKDYKKRLKAIILAQKQNDSNFQNKVIAKALDKANVKIKDKAFANIL 292
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 138-221 3.17e-28

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 104.30  E-value: 3.17e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  138 HILVK-DEAT----------AKKVKEELGQGK-SFEELAKQYSEDTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKKDEVS 205
Cdd:pfam00639   1 HILIKtPEASerdraeakakAEEILEQLKSGEdSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKPGEIS 80

                          90
                  ....*....|....*.
gi 446632696  206 EPVKTQFGYHIIKVTD 221
Cdd:pfam00639  81 GPVETRFGFHIIKLTD 96
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 116-223 6.92e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 101.29  E-value: 6.92e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  116 AIEKTITDKELKDNykpeVKASHILVKDEATAKKVKEELGQ-----------GKSFEELAKQYSEDTGSKEKGGDLGFFE 184
Cdd:pfam13616   2 SLSKLVDKKSAPDS----VKASHILISYSQAVSRTEEEAKAkadsllaalknGADFAALAKTYSDDPASKNNGGDLGWFT 77

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 446632696  185 HGKMVKEFEDAAYKLKKDEVSEPVKTQFGYHIIKVTDIK 223
Cdd:pfam13616  78 KGQMVKEFEDAVFSLKVGEISGVVKTQFGFHIIKVTDKK 116
PRK12450 PRK12450
foldase protein PrsA; Reviewed
 12-288 2.92e-26

foldase protein PrsA; Reviewed


Pssm-ID: 138982 [Multi-domain]  Cd Length: 309  Bit Score: 104.79  E-value: 2.92e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  12 SVIALSACGTGSSSDKIVTSKAGDITKDEFYNQMK-TQAGKQVLNNMVMEKVLIKNY--KVEDKEVDKKFDEMKKQYGDQ 88
Cdd:PRK12450  16 TVVTLSACQSSHNNTKLVSMKGDTITVSDFYNETKnTELAQKAMLSLVISRVFETQYanKVSDKEVEKAYKQTADQYGTS 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  89 FDTLLKQQGIKEETLKTGVRAQL-----AQEKAIEKTITDKELK---DNYKPEVKASHILVKDEATAKKVKEEL-GQGKS 159
Cdd:PRK12450  96 FKTVLAQSGLTPETYKKQIRLTKlveyaVKEQAKNETISKKDYRqayDAYTPTMTAEIMQFEKEEDAKAALEAVkAEGAD 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 160 FEELAKqysEDTGSKEKGGDLGFFE-HGKMVKEFEDAAYKLKKDEVSE------PVKTQFGYHIIKVTDIKEPEKSFEQS 232
Cdd:PRK12450 176 FAAIAK---EKTIAADKKTTYTFDSgETTLPAEVVRAASGLKEGNRSEiitaldPATSKRTYHIIKVTKKATKKADWKAY 252

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446632696 233 KADIKKEVVQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKTDAKKEDKK 288
Cdd:PRK12450 253 QKRLKDIIVTGKLKDPDFQNKVIAKALDKANVKIKDKAFANILAQFAKPNQKQPAQ 308
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 134-218 1.50e-20

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 84.69  E-value: 1.50e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 134 VKASHILVK--------------------DEATA--KKVKEELGQG-KSFEELAKQYSeDTGSKEKGGDLGFFEHGKMVK 190
Cdd:PTZ00356   6 VRAAHLLIKhtgsrnpvsrrtgkpvtrskEEAIKelAKWREQIVSGeKTFEEIARQRS-DCGSAAKGGDLGFFGRGQMQK 84

                         90       100
                 ....*....|....*....|....*...
gi 446632696 191 EFEDAAYKLKKDEVSEPVKTQFGYHIIK 218
Cdd:PTZ00356  85 PFEDAAFALKVGEISDIVHTDSGVHIIL 112
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 133-228 8.32e-17

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 79.78  E-value: 8.32e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 133 EVKASHILVK-------DEATAK--KVKEELGQGK-SFEELAKQYSEDTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKKD 202
Cdd:PRK10770 266 EVHARHILLKpspimtdEQARAKleQIAADIKSGKtTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALMRLNKG 345

                         90       100
                 ....*....|....*....|....*.
gi 446632696 203 EVSEPVKTQFGYHIIKVTDIKEPEKS 228
Cdd:PRK10770 346 QISAPVHSSFGWHLIELLDTRQVDKT 371
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 136-219 1.00e-16

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 73.90  E-value: 1.00e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 136 ASHILVKDEATAKKVKEELGQGKSFEELAKQYSEdTGSKEKGGDLGFFEHGKMVKEFEDAAYKLKKDEVSEPVKTQFGYH 215
Cdd:PRK15441   7 ALHILVKEEKLALDLLEQIKNGADFGKLAKKHSI-CPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYH 85


                 ....
gi 446632696 216 IIKV 219
Cdd:PRK15441  86 IIKV 89
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 120-248 2.33e-16

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 78.90  E-value: 2.33e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 120 TITDKELKDNYK--------PE-VKASHILVKDEATAKKVKEELGQGKSFEELAKQYSEDTGSKEKGGDLGFFEHGKMVK 190
Cdd:PRK10788 248 TVSDADIQAYYDqhqdqftqPErKRYSIIQTKTEAEAKAVLDELKKGADFATLAKEKSTDIISARNGGDLGWLEPATTPD 327

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 191 EFEDAAYKlKKDEVSEPVKTQFGYHIIKVTDIKePE--KSFEQSKADIKKEVVQKKAQDG 248
Cdd:PRK10788 328 ELKNAGLK-EKGQLSGVIKSSVGFLIVRLDDIQ-PAkvKPLSEVRDDIAAKVKQEKALDA 385
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
121-233 1.98e-10

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 57.45  E-value: 1.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  121 ITDKELKDNY--------KPEVKASHILVKDEATAKKVKEELGQGKSFEELAKQYSedtGSKEKGGDLGFFE-HGKMVKE 191
Cdd:pfam13145   1 VTEEELKAYYeenkdefsTPEGRLLEILVFKDQVAADAALALLKAGALEDFAALAK---GEGIKAATLDIVEsAELLPEE 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 446632696  192 FEDAAYKLKKDEVSEPVKTQFGYHIIKVTDIKEPE-KSFEQSK 233
Cdd:pfam13145  78 LAKAAFALKPGEVSGPIKTGNGYYVVRVTEIKPAQpLPFEEAK 120
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 52-223 1.80e-09

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 57.83  E-value: 1.80e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696  52 QVLNNMVMEKVLIK-----NYKVEDKEVDK-----------KFDEMKKQY---GDQFDTLLKQqgIKEETLKTGVRAQ-- 110
Cdd:PRK10770  51 QILERLIMDNIILQmaqkmGVKISDEQLDQaianiaaqnnmTLDQMRSRLaydGLNYNTYRNQ--IRKEMIISEVRNNev 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696 111 ------LAQE-KAIEKTITDKelkDNYKPEVKASHILV------------KDEATAKKVKEELGQGKSFEELAKQYSEDT 171
Cdd:PRK10770 129 rrritiLPQEvDSLAKQIGNQ---NDASTELNLSHILIplpenptqdqvdEAESQARSIVDQARNGADFGKLAIAYSADQ 205

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446632696 172 GSKeKGGDLGFFEHGKMVKEFEDAAYKLKKDEVSEPVKTQFGYHIIKVTDIK 223
Cdd:PRK10770 206 QAL-KGGQMGWGRIQELPGLFAQALSTAKKGDIVGPIRSGVGFHILKVNDLR 256
SurA_N_3 pfam13624
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 3-115 2.85e-05

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 433358 [Multi-domain]  Cd Length: 162  Bit Score: 43.33  E-value: 2.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446632696    3 KAMLALAATSVIALSACGTGSSSDKIVtSKAGD--ITKDEF-------YNQMKTQAG--------------KQVLNNMVM 59
Cdd:pfam13624  15 KIILGLIILSFVFWGVGSYFSGGGGAV-AKVNGekISRAEFqrayrrqLDQLRQQFGpnldaelldelglrQQVLDQLID 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446632696   60 EKVLIKNYK-----VEDKEVDK------------KFDEmkkqygDQFDTLLKQQGIKEETLKTGVRAQLAQEK 115
Cdd:pfam13624  94 RALLLQEAKklglaVSDEEVRQaiasipafqedgKFDK------ERYRQLLRANGLTPAEFEASLRQDLLLQQ 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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