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Conserved domains on  [gi|446633057|ref|WP_000710403|]
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MULTISPECIES: acetyl-CoA carboxylase carboxyltransferase subunit alpha [Acinetobacter]

Protein Classification

acetyl-CoA carboxylase carboxyltransferase subunit alpha( domain architecture ID 10002787)

acetyl-CoA carboxylase carboxyltransferase subunit alpha (AccA) is a component of the acetyl coenzyme A carboxylase (ACC) complex that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA

CATH:  3.90.226.10
EC:  2.1.3.15
Gene Ontology:  GO:0003989|GO:0005524|GO:0016743|GO:0006633|GO:0005524|GO:0009317
PubMed:  1355089
SCOP:  4000456

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AccA COG0825
Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase ...
 9-266 3.94e-157

Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase alpha subunit is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440587 [Multi-domain]  Cd Length: 315  Bit Score: 439.47  E-value: 3.94e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057   9 AWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEG 88
Cdd:COG0825   54 PWQKVQLARHPQRPYTLDYIEAIFTDFIELHGDRAFGDDPAIVGGLARFDGRPVMVIGHQKGRDTKERIKRNFGMPHPEG 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  89 YRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATV-----------LGeggsgga 157
Cdd:COG0825  134 YRKALRLMKLAEKFGLPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLKVPIISVVigeggsggalaIG------- 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 158 lgigVADRVIMLSHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEGE-GAHLDPERVMQNLKV 236
Cdd:COG0825  207 ----VGDRVLMLEHSIYSVISPEGCASILWKDASKAPEAAEALKITAQDLKELGIIDEIIPEPLgGAHRDPEAAAENLKE 282

                        250       260       270
                 ....*....|....*....|....*....|
gi 446633057 237 VLKQALDELLPMDANERCEARYQRLMKFGS 266
Cdd:COG0825  283 ALLKALKELKGLSPEELLEQRYEKFRAIGR 312
 
Name Accession Description Interval E-value
AccA COG0825
Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase ...
 9-266 3.94e-157

Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase alpha subunit is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440587 [Multi-domain]  Cd Length: 315  Bit Score: 439.47  E-value: 3.94e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057   9 AWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEG 88
Cdd:COG0825   54 PWQKVQLARHPQRPYTLDYIEAIFTDFIELHGDRAFGDDPAIVGGLARFDGRPVMVIGHQKGRDTKERIKRNFGMPHPEG 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  89 YRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATV-----------LGeggsgga 157
Cdd:COG0825  134 YRKALRLMKLAEKFGLPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLKVPIISVVigeggsggalaIG------- 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 158 lgigVADRVIMLSHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEGE-GAHLDPERVMQNLKV 236
Cdd:COG0825  207 ----VGDRVLMLEHSIYSVISPEGCASILWKDASKAPEAAEALKITAQDLKELGIIDEIIPEPLgGAHRDPEAAAENLKE 282

                        250       260       270
                 ....*....|....*....|....*....|
gi 446633057 237 VLKQALDELLPMDANERCEARYQRLMKFGS 266
Cdd:COG0825  283 ALLKALKELKGLSPEELLEQRYEKFRAIGR 312
PRK05724 PRK05724
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated
 8-266 6.93e-150

acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated


Pssm-ID: 235580 [Multi-domain]  Cd Length: 319  Bit Score: 421.47  E-value: 6.93e-150
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057   8 KAWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPE 87
Cdd:PRK05724  56 TPWQKVQLARHPQRPYTLDYIELLFTDFTELHGDRAFADDKAIVGGLARLNGRPVMVIGHQKGRDTKEKIRRNFGMPRPE 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  88 GYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVI 167
Cdd:PRK05724 136 GYRKALRLMKMAEKFGLPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLKVPIICTVIGEGGSGGALAIGVGDRVL 215

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 168 MLSHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDE--GeGAHLDPERVMQNLKVVLKQALDEL 245
Cdd:PRK05724 216 MLEYSTYSVISPEGCASILWKDASKAPEAAEAMKITAQDLKELGIIDEIIPEplG-GAHRDPEAAAAALKEALLEALAEL 294

                        250       260
                 ....*....|....*....|.
gi 446633057 246 LPMDANERCEARYQRLMKFGS 266
Cdd:PRK05724 295 KGLSPEELLERRYEKFMSIGR 315
AccA_sub NF041504
carboxyltransferase subunit alpha;
10-265 3.44e-134

carboxyltransferase subunit alpha;


Pssm-ID: 469391 [Multi-domain]  Cd Length: 257  Bit Score: 379.49  E-value: 3.44e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  10 WTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEGY 89
Cdd:NF041504   1 WQKVQVARHPDRPHALDYIAALFTDFTELHGDRLFGDDPAIVGGLGRFRGRPVTVIGQEKGSDTEERLRHNFGMARPEGY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  90 RKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVIML 169
Cdd:NF041504  81 RKALRLMELAEKFGRPVITLIDTPGAYPGVGAEERGQAEAIARSIEAMLQLTVPNIAVIIGEGGSGGALALANANRVLML 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 170 SHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEGE-GAHLDPERVMQNLKVVLKQALDELLPM 248
Cdd:NF041504 161 EHAIYSVISPEGCASILWRDASRAQEAAEALKLTAQDLLKLGLIDQIIPEPLgGAHRDPAALIAALGDAIEEALAELAGL 240

                        250
                 ....*....|....*..
gi 446633057 249 DANERCEARYQRLMKFG 265
Cdd:NF041504 241 SADELIAQRREKFLAMG 257
accA TIGR00513
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; The enzyme acetyl-CoA carboxylase ...
 8-266 5.42e-115

acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; The enzyme acetyl-CoA carboxylase contains a biotin carboxyl carrier protein or domain, a biotin carboxylase, and a carboxyl transferase. This model represents the alpha chain of the carboxyl transferase for cases in which the architecture of the protein is as in E. coli, in which the carboxyltransferase portion consists of two non-identical subnits, alpha and beta. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 273113 [Multi-domain]  Cd Length: 316  Bit Score: 332.93  E-value: 5.42e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057    8 KAWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPE 87
Cdd:TIGR00513  56 GAWQRLQLARHPDRPYTLDYIELIFDDFFELAGDRAYADDKAIVGGIARLDGRPVVVIGHQKGRDTKEKLRRNFGMPAPE 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057   88 GYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVI 167
Cdd:TIGR00513 136 GYRKALRLMKMAERFKMPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLGVPVICTVIGEGGSGGALAIGVGDKVN 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  168 MLSHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEGE-GAHLDPERVMQNLKVVLKQALDELL 246
Cdd:TIGR00513 216 MLEYSTYSVISPEGCAAILWKDASKAPKAAEAMKITAPDLKELGLIDSIIPEPLgGAHRNPLAAAASLKEQLLADLATLD 295

                         250       260
                  ....*....|....*....|
gi 446633057  247 PMDANERCEARYQRLMKFGS 266
Cdd:TIGR00513 296 QLSTEELKNRRYQKLMSLGY 315
ACCA pfam03255
Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Acetyl co-enzyme A ...
 9-100 3.73e-60

Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Acetyl co-enzyme A carboxylase carboxyltransferase is composed of an alpha and beta subunit.


Pssm-ID: 427221 [Multi-domain]  Cd Length: 144  Bit Score: 187.23  E-value: 3.73e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057    9 AWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEG 88
Cdd:pfam03255  53 PWQKVQLARHPERPYTLDYIEALFDDFIELHGDRLFGDDPAIVGGLARFDGQPVMVIGHQKGRDTKENIKRNFGMPHPEG 132

                          90
                  ....*....|..
gi 446633057   89 YRKSQRLLDMAE 100
Cdd:pfam03255 133 YRKALRLMKLAE 144
 
Name Accession Description Interval E-value
AccA COG0825
Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase ...
 9-266 3.94e-157

Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase alpha subunit is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440587 [Multi-domain]  Cd Length: 315  Bit Score: 439.47  E-value: 3.94e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057   9 AWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEG 88
Cdd:COG0825   54 PWQKVQLARHPQRPYTLDYIEAIFTDFIELHGDRAFGDDPAIVGGLARFDGRPVMVIGHQKGRDTKERIKRNFGMPHPEG 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  89 YRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATV-----------LGeggsgga 157
Cdd:COG0825  134 YRKALRLMKLAEKFGLPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLKVPIISVVigeggsggalaIG------- 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 158 lgigVADRVIMLSHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEGE-GAHLDPERVMQNLKV 236
Cdd:COG0825  207 ----VGDRVLMLEHSIYSVISPEGCASILWKDASKAPEAAEALKITAQDLKELGIIDEIIPEPLgGAHRDPEAAAENLKE 282

                        250       260       270
                 ....*....|....*....|....*....|
gi 446633057 237 VLKQALDELLPMDANERCEARYQRLMKFGS 266
Cdd:COG0825  283 ALLKALKELKGLSPEELLEQRYEKFRAIGR 312
PRK05724 PRK05724
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated
 8-266 6.93e-150

acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated


Pssm-ID: 235580 [Multi-domain]  Cd Length: 319  Bit Score: 421.47  E-value: 6.93e-150
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057   8 KAWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPE 87
Cdd:PRK05724  56 TPWQKVQLARHPQRPYTLDYIELLFTDFTELHGDRAFADDKAIVGGLARLNGRPVMVIGHQKGRDTKEKIRRNFGMPRPE 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  88 GYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVI 167
Cdd:PRK05724 136 GYRKALRLMKMAEKFGLPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLKVPIICTVIGEGGSGGALAIGVGDRVL 215

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 168 MLSHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDE--GeGAHLDPERVMQNLKVVLKQALDEL 245
Cdd:PRK05724 216 MLEYSTYSVISPEGCASILWKDASKAPEAAEAMKITAQDLKELGIIDEIIPEplG-GAHRDPEAAAAALKEALLEALAEL 294

                        250       260
                 ....*....|....*....|.
gi 446633057 246 LPMDANERCEARYQRLMKFGS 266
Cdd:PRK05724 295 KGLSPEELLERRYEKFMSIGR 315
AccA_sub NF041504
carboxyltransferase subunit alpha;
10-265 3.44e-134

carboxyltransferase subunit alpha;


Pssm-ID: 469391 [Multi-domain]  Cd Length: 257  Bit Score: 379.49  E-value: 3.44e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  10 WTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEGY 89
Cdd:NF041504   1 WQKVQVARHPDRPHALDYIAALFTDFTELHGDRLFGDDPAIVGGLGRFRGRPVTVIGQEKGSDTEERLRHNFGMARPEGY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  90 RKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVIML 169
Cdd:NF041504  81 RKALRLMELAEKFGRPVITLIDTPGAYPGVGAEERGQAEAIARSIEAMLQLTVPNIAVIIGEGGSGGALALANANRVLML 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 170 SHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEGE-GAHLDPERVMQNLKVVLKQALDELLPM 248
Cdd:NF041504 161 EHAIYSVISPEGCASILWRDASRAQEAAEALKLTAQDLLKLGLIDQIIPEPLgGAHRDPAALIAALGDAIEEALAELAGL 240

                        250
                 ....*....|....*..
gi 446633057 249 DANERCEARYQRLMKFG 265
Cdd:NF041504 241 SADELIAQRREKFLAMG 257
accA TIGR00513
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; The enzyme acetyl-CoA carboxylase ...
 8-266 5.42e-115

acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; The enzyme acetyl-CoA carboxylase contains a biotin carboxyl carrier protein or domain, a biotin carboxylase, and a carboxyl transferase. This model represents the alpha chain of the carboxyl transferase for cases in which the architecture of the protein is as in E. coli, in which the carboxyltransferase portion consists of two non-identical subnits, alpha and beta. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 273113 [Multi-domain]  Cd Length: 316  Bit Score: 332.93  E-value: 5.42e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057    8 KAWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPE 87
Cdd:TIGR00513  56 GAWQRLQLARHPDRPYTLDYIELIFDDFFELAGDRAYADDKAIVGGIARLDGRPVVVIGHQKGRDTKEKLRRNFGMPAPE 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057   88 GYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVI 167
Cdd:TIGR00513 136 GYRKALRLMKMAERFKMPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLGVPVICTVIGEGGSGGALAIGVGDKVN 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  168 MLSHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEGE-GAHLDPERVMQNLKVVLKQALDELL 246
Cdd:TIGR00513 216 MLEYSTYSVISPEGCAAILWKDASKAPKAAEAMKITAPDLKELGLIDSIIPEPLgGAHRNPLAAAASLKEQLLADLATLD 295

                         250       260
                  ....*....|....*....|
gi 446633057  247 PMDANERCEARYQRLMKFGS 266
Cdd:TIGR00513 296 QLSTEELKNRRYQKLMSLGY 315
PRK12319 PRK12319
acetyl-CoA carboxylase subunit alpha; Provisional
 13-264 2.06e-85

acetyl-CoA carboxylase subunit alpha; Provisional


Pssm-ID: 183435 [Multi-domain]  Cd Length: 256  Bit Score: 255.86  E-value: 2.06e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  13 VQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEGYRKS 92
Cdd:PRK12319   8 LKEARDQGRLTTLDYATLIFDDFMELHGDRHFRDDGAVVGGIGYLAGQPVTVVGIQKGKNLQDNLKRNFGQPHPEGYRKA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  93 QRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVIMLSHS 172
Cdd:PRK12319  88 LRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENT 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 173 IYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEgegAHLDPERVMQNLKVVLKQALDELLPMDANE 252
Cdd:PRK12319 168 MYAVLSPEGFASILWKDGSRATEAAELMKITAGELLEMGVVDKVIPE---HGYFSSEIIDMIKKNLIEELAQLSQKPLEQ 244

                        250
                 ....*....|..
gi 446633057 253 RCEARYQRLMKF 264
Cdd:PRK12319 245 LLEERYQRFRKY 256
accA CHL00198
acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional
 13-265 7.69e-83

acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional


Pssm-ID: 214393 [Multi-domain]  Cd Length: 322  Bit Score: 251.27  E-value: 7.69e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  13 VQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEGYRKS 92
Cdd:CHL00198  64 LHLVRQSERPTTLDYIPYILDEWIELHGDRGGSDDPALVGGIGKINGRTIVFLGHQRGRNTKENVLRNFGMPSPGGYRKA 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  93 QRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVIMLSHS 172
Cdd:CHL00198 144 LRLMKHANKFGLPILTFIDTPGAWAGVKAEKLGQGEAIAVNLREMFSFEVPIICTIIGEGGSGGALGIGIGDSIMMLEYA 223

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 173 IYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEGEG-AHLDPERVMQNLKVVLKQALDELLPMDAN 251
Cdd:CHL00198 224 VYTVATPEACAAILWKDSKKSLDAAEALKITSEDLKVLGIIDEIIPEPIGgAQADPASASKILKKKLIRQLDFLKILSPS 303

                        250
                 ....*....|....
gi 446633057 252 ERCEARYQRLMKFG 265
Cdd:CHL00198 304 ELKAHRYEKFRKLG 317
PLN03230 PLN03230
acetyl-coenzyme A carboxylase carboxyl transferase; Provisional
 13-265 2.19e-78

acetyl-coenzyme A carboxylase carboxyl transferase; Provisional


Pssm-ID: 178769 [Multi-domain]  Cd Length: 431  Bit Score: 243.70  E-value: 2.19e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  13 VQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEGYRKS 92
Cdd:PLN03230 131 LSVARHPNRPTFLDHVLNMTDKWVELHGDRAGFDDPAIVCGIGSMEGMSFMFIGHQKGRNTKENIYRNFAMPQPNGYRKA 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  93 QRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVIMLSHS 172
Cdd:PLN03230 211 LRFMRHAEKFGFPILTFVDTPGAYAGIKAEELGQGEAIAFNLREMFGLRVPIIATVIGEGGSGGALAIGCGNRMLMMENA 290

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 173 IYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEG-EGAHLDPERVMQNLKVVLKQALDELLPMDAN 251
Cdd:PLN03230 291 VYYVASPEACAAILWKSAAAAPKAAEALRITAAELVKLGVVDEIVPEPlGGAHSDPLQASKNIKEVILRHMKELMKMDPE 370

                        250
                 ....*....|....
gi 446633057 252 ERCEARYQRLMKFG 265
Cdd:PLN03230 371 ELLQDRAAKFRKIG 384
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 13-265 3.80e-66

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 219.34  E-value: 3.80e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  13 VQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEGYRKS 92
Cdd:PLN03229 152 VNIARHPNRPTFLDHIFNITDKFVELHGDRAGYDDPAIVTGIGTIDGKRYMFIGHQKGRNTKENIMRNFGMPTPHGYRKA 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  93 QRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVIMLSHS 172
Cdd:PLN03229 232 LRMMYYADHHGFPIVTFIDTPGAYADLKSEELGQGEAIAHNLRTMFGLKVPIVSIVIGEGGSGGALAIGCANKLLMLENA 311

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057 173 IYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEG-EGAHLDPERVMQNLKVVLKQALDELLPMDAN 251
Cdd:PLN03229 312 VFYVASPEACAAILWKSAKAAPKAAEKLRITAQELCRLQIADGIIPEPlGGAHADPSWTSQQIKIAINENMDELGKMDTE 391

                        250
                 ....*....|....
gi 446633057 252 ERCEARYQRLMKFG 265
Cdd:PLN03229 392 ELLKHRMLKFRKIG 405
ACCA pfam03255
Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Acetyl co-enzyme A ...
 9-100 3.73e-60

Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Acetyl co-enzyme A carboxylase carboxyltransferase is composed of an alpha and beta subunit.


Pssm-ID: 427221 [Multi-domain]  Cd Length: 144  Bit Score: 187.23  E-value: 3.73e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057    9 AWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEG 88
Cdd:pfam03255  53 PWQKVQLARHPERPYTLDYIEALFDDFIELHGDRLFGDDPAIVGGLARFDGQPVMVIGHQKGRDTKENIKRNFGMPHPEG 132

                          90
                  ....*....|..
gi 446633057   89 YRKSQRLLDMAE 100
Cdd:pfam03255 133 YRKALRLMKLAE 144
Carboxyl_trans pfam01039
Carboxyl transferase domain; All of the members in this family are biotin dependent ...
 50-194 9.39e-11

Carboxyl transferase domain; All of the members in this family are biotin dependent carboxylases. The carboxyl transferase domain carries out the following reaction; transcarboxylation from biotin to an acceptor molecule. There are two recognized types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxoacid as the acceptor molecule of carbon dioxide. All of the members in this family utilize acyl-CoA as the acceptor molecule.


Pssm-ID: 426008 [Multi-domain]  Cd Length: 491  Bit Score: 61.51  E-value: 9.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057   50 MVGGLARFDGQPVMVIGQHRgrstreklKHNFGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEA 129
Cdd:pfam01039 282 VVTGFARLGGIPVGVVANQP--------RVGAGVLFPDSADKAARFIRDCDAFNLPLVILADVPGFLPGQRQEYGGILKH 353

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  130 IATSLAQLSSLKVPVIaTVLGEGG-----SGGALGIGVADRVIMLSHSIYSVISPEGCASILWKTAEKAA 194
Cdd:pfam01039 354 GAKLLYALAEATVPKI-TVIPRKAyggayVVMDSKINGADINFAWPTARIAVMGPEGAVEIKFRKEKAAA 422
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
32-149 6.97e-08

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 53.11  E-value: 6.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  32 FTEFDALHGDRLFGDD-----GAMVGGLARFDGQPVMVIGQhrgrstreklkhNF----GMCNPEGYRKSQRLLDMAERF 102
Cdd:COG4799   49 FLELGALAGHRMYDDDdrvpgDGVVTGIGTVDGRPVVVVAN------------DFtvkgGSLGPMTAKKILRAQDIALEN 116

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 446633057 103 NLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQlSSLKVPVIATVL 149
Cdd:COG4799  117 GLPVIYLVDSGGARLQEGVESFAGYGRIFYRNAR-SSGGIPQISVIM 162
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
34-149 4.22e-05

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 44.63  E-value: 4.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  34 EFDALHgdRLFGDdgAMVGGLARFDGQPVMVIGQHRgrstreklKHNFGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTM 113
Cdd:COG4799  292 SFFEFK--PLYGP--NIVTGFARIDGRPVGIVANQP--------MVLAGVLDIDAADKAARFIRLCDAFNIPLVFLVDVP 359

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446633057 114 GAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVL 149
Cdd:COG4799  360 GFMVGTEQERGGIIRHGAKLLYAVAEATVPKITVIL 395
PLN02820 PLN02820
3-methylcrotonyl-CoA carboxylase, beta chain
 15-149 8.73e-04

3-methylcrotonyl-CoA carboxylase, beta chain


Pssm-ID: 178415 [Multi-domain]  Cd Length: 569  Bit Score: 40.56  E-value: 8.73e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446633057  15 IARHPERPQFL-----DYV---GEIFTEFDALHGDRLFGDD---GAMVGGLARFDGQPVMVIGQH---RGrstreklkhn 80
Cdd:PLN02820  73 VKRHRSRNKLLpreriDRLldpGSPFLELSQLAGHELYGEDlpsGGIVTGIGPVHGRLCMFVANDptvKG---------- 142

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446633057  81 fGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAE---ERGQAEAIATSLAQLSSLKVPVIATVL 149
Cdd:PLN02820 143 -GTYYPITVKKHLRAQEIAAQCRLPCIYLVDSGGANLPRQAEvfpDRDHFGRIFYNQARMSSAGIPQIALVL 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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