NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|446635905|ref|WP_000713251|]
View 

MULTISPECIES: transglycosylase SLT domain-containing protein [Bacillus cereus group]

Protein Classification

lysozyme family protein( domain architecture ID 63)

lysozyme family protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Lyz-like super family cl00222
lysozyme-like domains; This family contains several members, including soluble lytic ...
 47-122 1.06e-06

lysozyme-like domains; This family contains several members, including soluble lytic transglycosylases (SLT), goose egg-white lysozymes (GEWL), hen egg-white lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, chitosanases, and pesticin. Typical members are involved in the hydrolysis of beta-1,4- linked polysaccharides.


The actual alignment was detected with superfamily member pfam01464:

Pssm-ID: 469668 [Multi-domain]  Cd Length: 114  Bit Score: 45.38  E-value: 1.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446635905   47 IIEEAKKVNLPEWIPLTIAEHESRLNPRSVGDNGtSFGLFQL--HRGGGLAPE-HLTDDELKDPRTNAQIA---MPHLMK 120
Cdd:pfam01464   1 IIKAAQKYGVDPSLLLAIAQQESGFNPKAVSKSG-AVGLMQImpSTAKRLGLRvNPGVDDLFDPEKNIKAGtkyLKELYK 79


                  ..
gi 446635905  121 GY 122
Cdd:pfam01464  80 QY 81
 
Name Accession Description Interval E-value
SLT pfam01464
Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found ...
 47-122 1.06e-06

Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.


Pssm-ID: 396169 [Multi-domain]  Cd Length: 114  Bit Score: 45.38  E-value: 1.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446635905   47 IIEEAKKVNLPEWIPLTIAEHESRLNPRSVGDNGtSFGLFQL--HRGGGLAPE-HLTDDELKDPRTNAQIA---MPHLMK 120
Cdd:pfam01464   1 IIKAAQKYGVDPSLLLAIAQQESGFNPKAVSKSG-AVGLMQImpSTAKRLGLRvNPGVDDLFDPEKNIKAGtkyLKELYK 79


                  ..
gi 446635905  121 GY 122
Cdd:pfam01464  80 QY 81
MltE COG0741
Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin ...
 44-140 5.08e-04

Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440504 [Multi-domain]  Cd Length: 244  Bit Score: 39.21  E-value: 5.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446635905  44 KQIIIEEAKKVNL-PEWIpLTIAEHESRLNPRSVGDNGTSfGLFQL--------HRGGGLAPehlTDDELKDPRTNAQIA 114
Cdd:COG0741  104 LPLIEEAAKKYGVdPALV-LALIRQESAFNPNAVSPAGAR-GLMQLmpatarrlGLKLGLGP---SPDDLFDPETNIRAG 178

                         90       100
                 ....*....|....*....|....*.
gi 446635905 115 MPHLMKGYKRgvQKGLTDFALLKYIA 140
Cdd:COG0741  179 AAYLRELLDR--FDGDLVLALAAYNA 202
GEWL cd01021
Goose egg-white lysozyme; Eukaryotic goose-type or G-type lysozyme (goose egg-white lysozyme; ...
 36-90 4.42e-03

Goose egg-white lysozyme; Eukaryotic goose-type or G-type lysozyme (goose egg-white lysozyme; GEWL) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc). Mammals have two lysozymes. This family corresponds to human and mouse lysozyme G-like protein 2.


Pssm-ID: 381601 [Multi-domain]  Cd Length: 174  Bit Score: 36.04  E-value: 4.42e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446635905  36 DSEEAKQMKQIIIEEAKKVNLPEWIPLTIAEHESR----LNPRSVGDNGTSFGLFQLHR 90
Cdd:cd01021   30 DLNRLNKYKDCIKQVGKKLCIDPALIAAIISRESRagaaLDKNGWGDHGNGFGLMQVDK 88
 
Name Accession Description Interval E-value
SLT pfam01464
Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found ...
 47-122 1.06e-06

Transglycosylase SLT domain; This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.


Pssm-ID: 396169 [Multi-domain]  Cd Length: 114  Bit Score: 45.38  E-value: 1.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446635905   47 IIEEAKKVNLPEWIPLTIAEHESRLNPRSVGDNGtSFGLFQL--HRGGGLAPE-HLTDDELKDPRTNAQIA---MPHLMK 120
Cdd:pfam01464   1 IIKAAQKYGVDPSLLLAIAQQESGFNPKAVSKSG-AVGLMQImpSTAKRLGLRvNPGVDDLFDPEKNIKAGtkyLKELYK 79


                  ..
gi 446635905  121 GY 122
Cdd:pfam01464  80 QY 81
MltE COG0741
Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin ...
 44-140 5.08e-04

Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440504 [Multi-domain]  Cd Length: 244  Bit Score: 39.21  E-value: 5.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446635905  44 KQIIIEEAKKVNL-PEWIpLTIAEHESRLNPRSVGDNGTSfGLFQL--------HRGGGLAPehlTDDELKDPRTNAQIA 114
Cdd:COG0741  104 LPLIEEAAKKYGVdPALV-LALIRQESAFNPNAVSPAGAR-GLMQLmpatarrlGLKLGLGP---SPDDLFDPETNIRAG 178

                         90       100
                 ....*....|....*....|....*.
gi 446635905 115 MPHLMKGYKRgvQKGLTDFALLKYIA 140
Cdd:COG0741  179 AAYLRELLDR--FDGDLVLALAAYNA 202
GEWL cd01021
Goose egg-white lysozyme; Eukaryotic goose-type or G-type lysozyme (goose egg-white lysozyme; ...
 36-90 4.42e-03

Goose egg-white lysozyme; Eukaryotic goose-type or G-type lysozyme (goose egg-white lysozyme; GEWL) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc). Mammals have two lysozymes. This family corresponds to human and mouse lysozyme G-like protein 2.


Pssm-ID: 381601 [Multi-domain]  Cd Length: 174  Bit Score: 36.04  E-value: 4.42e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446635905  36 DSEEAKQMKQIIIEEAKKVNLPEWIPLTIAEHESR----LNPRSVGDNGTSFGLFQLHR 90
Cdd:cd01021   30 DLNRLNKYKDCIKQVGKKLCIDPALIAAIISRESRagaaLDKNGWGDHGNGFGLMQVDK 88
LYZ_C cd16897
C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). ...
 38-88 4.65e-03

C-type lysozyme; C-type lysozyme (chicken or conventional type; 1, 4-beta-N-acetylmuramidase). In humans, lysozyme is found in a wide variety of tissue types and body fluids. It has bacteriolytic properties through the hydolysis of beta-1,4, glyocosidic linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan, as well as between N-acetyl-D-glucosamine residues in chitodextrins. This family also includes digestive stomach lysozyme, which allow ruminants to digest bacteria in the foregut. The mammalian enzyme is related to lysozyme found hen egg-whites and related species.


Pssm-ID: 340383  Cd Length: 126  Bit Score: 35.32  E-value: 4.65e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446635905  38 EEAKQMKQIIIEEAKKVNLPEWIPLtiAEHESRLNPRSVGDN---GTSFGLFQL 88
Cdd:cd16897    7 ELARILKRGGLDGYRGYSLANWVCL--AYYESGFNTRATNENpdgSTDYGIFQI 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH