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Conserved domains on  [gi|446638663|ref|WP_000716009|]
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MULTISPECIES: omptin family outer membrane protease PgtE [Salmonella]

Protein Classification

omptin family outer membrane protease( domain architecture ID 10013698)

omptin family outer membrane protease similar to Escherichia coli protease VII that can cleave T7 RNA polymerase, ferric enterobactin receptor protein (FEP), antimicrobial peptide protamine and other proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10993 PRK10993
omptin family outer membrane protease;
1-312 2.10e-180

omptin family outer membrane protease;


:

Pssm-ID: 236813  Cd Length: 314  Bit Score: 500.32  E-value: 2.10e-180
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663   1 MKKHAIAVMMIAVFSESVYAESTLFIPDVSPDSVTTSLSVGVLNGKSRELVYDTDTGRKISQLDWKIKNVATLQGDLSWE 80
Cdd:PRK10993   1 MKKKLLAIALIAPLAISAFASTATASFDVTPDNVSVSISLGTLSGKSKELVYDEEGGRKLSQLDWKIKNAAIIKGDINWD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  81 PYSFMTLDARGWTSLASGSGHMVDHDWMSSEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRFS 160
Cdd:PRK10993  81 LLPRLSLGASGWTTLASGGGHMVDYDWLDSSQPGWTDRSHHPDTDLNYANEFDLNLKGWLLQNPNYRLGVMAGYQETRFS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663 161 WTARGGSYIYDNG---RYIGNFPHGVRGIGYSQRFEMPYIGLAGDYRINDFECNVLFKYSDWVNAHDNDEHYMRKLTFRE 237
Cdd:PRK10993 161 WTAYGGSYIYSNGgfrDDIGTFPDGERGIGYKQRFKMPYIGLTGSYRYDDFEFGGLLKYSGWVSASDNDEHYLRNLTFRD 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446638663 238 KTENSRYYGASIDAGYYITSNAKIFAEFAYSKYEEGKGGTQIIDKTSGDTAYFgGDAAGIANNNYTVTAGLQYRF 312
Cdd:PRK10993 241 KFKNSPYYSASINAGYYVTPNAKLYVEGAYNRYFEGKGDTQIYDHATGTSSYF-KDAAGIENQNYTVTAGLKYRF 314
 
Name Accession Description Interval E-value
PRK10993 PRK10993
omptin family outer membrane protease;
1-312 2.10e-180

omptin family outer membrane protease;


Pssm-ID: 236813  Cd Length: 314  Bit Score: 500.32  E-value: 2.10e-180
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663   1 MKKHAIAVMMIAVFSESVYAESTLFIPDVSPDSVTTSLSVGVLNGKSRELVYDTDTGRKISQLDWKIKNVATLQGDLSWE 80
Cdd:PRK10993   1 MKKKLLAIALIAPLAISAFASTATASFDVTPDNVSVSISLGTLSGKSKELVYDEEGGRKLSQLDWKIKNAAIIKGDINWD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  81 PYSFMTLDARGWTSLASGSGHMVDHDWMSSEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRFS 160
Cdd:PRK10993  81 LLPRLSLGASGWTTLASGGGHMVDYDWLDSSQPGWTDRSHHPDTDLNYANEFDLNLKGWLLQNPNYRLGVMAGYQETRFS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663 161 WTARGGSYIYDNG---RYIGNFPHGVRGIGYSQRFEMPYIGLAGDYRINDFECNVLFKYSDWVNAHDNDEHYMRKLTFRE 237
Cdd:PRK10993 161 WTAYGGSYIYSNGgfrDDIGTFPDGERGIGYKQRFKMPYIGLTGSYRYDDFEFGGLLKYSGWVSASDNDEHYLRNLTFRD 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446638663 238 KTENSRYYGASIDAGYYITSNAKIFAEFAYSKYEEGKGGTQIIDKTSGDTAYFgGDAAGIANNNYTVTAGLQYRF 312
Cdd:PRK10993 241 KFKNSPYYSASINAGYYVTPNAKLYVEGAYNRYFEGKGDTQIYDHATGTSSYF-KDAAGIENQNYTVTAGLKYRF 314
Omptin pfam01278
Omptin family; The omptin family is a family of serine proteases.
 30-312 2.06e-164

Omptin family; The omptin family is a family of serine proteases.


Pssm-ID: 426174  Cd Length: 282  Bit Score: 458.36  E-value: 2.06e-164
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663   30 SPDSVTTSLSVGVLNGKSRELVYDTDTGRKISQLDWKIKNVATLQGDLSWEPYSFMTLDARGWTSLASGSGHMVDHDWMS 109
Cdd:pfam01278   1 TPDNFSLSTSLGVLSGKAKEYVYDPETGRKLSQLDWKIKNAAIIKGEIEWDITPRLTLSASGWTTLASGSGVMDDYDWLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  110 SEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRFSWTARGGSYIYDNGRYIGNFPHGVRGIGYS 189
Cdd:pfam01278  81 PNQPTWTDWSHHPDTQLNYANEADLNAKGWLLQQNNYRLGALAGYQETRFSWTARGGSYSYNNGTDIGSFPDGVRGIGYK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  190 QRFEMPYIGLAGDYRINDFECNVLFKYSDWVNAHDNDEHYMRKLTFREKTENSRYYGASIDAGYYITSNAKIFAEFAYSK 269
Cdd:pfam01278 161 QRFKMPYIGLAGSYRINNFEFNALLKYSPWVRARDNDNHYLRSLTFKDKSKNSNYYSLSINAGYYVTPNAKLFLEAAWNR 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 446638663  270 YEEGKGGTQIIDKTSGDTAYFgGDAAGIANNNYTVTAGLQYRF 312
Cdd:pfam01278 241 YSNGKGDTTILDNRTGTSSVG-ENSAGIENQNYTLTVGLQYRF 282
OmpT COG4571
Outer membrane protease [Cell wall/membrane/envelope biogenesis];
1-312 5.54e-159

Outer membrane protease [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443628  Cd Length: 315  Bit Score: 445.97  E-value: 5.54e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663   1 MKKHAIAV-MMIAVFSESVYAESTLFIPDVSPDSVTTSLSVGVLNGKSRELVYDTDTGRKISQLDWKIKNVATLQGDLSW 79
Cdd:COG4571    1 MKKKLLVAlFLLAPLALPALANAATVEPEFTPDSVSFSLSLGVLSGESKEYVYDPDGGRKLSQLDWKIDNAPIIKGGLSW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  80 EPYSFMTLDARGWTSLASGSGHMVDHDWMSSEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRF 159
Cdd:COG4571   81 DPLPWLSLGASGWTTLGSGSGYMDDYDWLNPGQTDWTDWSSHPKTRLNYANEFDLNAKGWLLKENNYSLGVLAGYQEDRF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663 160 SWTARGGSYIYDNG---RYIGNFPHGVRGIGYSQRFEMPYIGLAGDYRINDFECNVLFKYSDWVNAHDNDEHYMRKLTFR 236
Cdd:COG4571  161 SWTARGGSYIYSDNgfrDDVGTFPDGEKGISYKQRFKVPYIGLTGSYRYGNWEFGGLLKYSPWVRARDNDHHYLRDLTFK 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446638663 237 EKTENSRYYGASIDAGYYITSNAKIFAEFAYSKYEEGKGGTQIIDKTSGDTAYfGGDAAGIANNNYTVTAGLQYRF 312
Cdd:COG4571  241 DKFKNSNYYSLSLNAGYYVTPNLKFFVEASYSRYTEAKGDTTIYDLTTGTSSY-GGDAAGIDNYSYTVSLGLKYRF 315
 
Name Accession Description Interval E-value
PRK10993 PRK10993
omptin family outer membrane protease;
1-312 2.10e-180

omptin family outer membrane protease;


Pssm-ID: 236813  Cd Length: 314  Bit Score: 500.32  E-value: 2.10e-180
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663   1 MKKHAIAVMMIAVFSESVYAESTLFIPDVSPDSVTTSLSVGVLNGKSRELVYDTDTGRKISQLDWKIKNVATLQGDLSWE 80
Cdd:PRK10993   1 MKKKLLAIALIAPLAISAFASTATASFDVTPDNVSVSISLGTLSGKSKELVYDEEGGRKLSQLDWKIKNAAIIKGDINWD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  81 PYSFMTLDARGWTSLASGSGHMVDHDWMSSEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRFS 160
Cdd:PRK10993  81 LLPRLSLGASGWTTLASGGGHMVDYDWLDSSQPGWTDRSHHPDTDLNYANEFDLNLKGWLLQNPNYRLGVMAGYQETRFS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663 161 WTARGGSYIYDNG---RYIGNFPHGVRGIGYSQRFEMPYIGLAGDYRINDFECNVLFKYSDWVNAHDNDEHYMRKLTFRE 237
Cdd:PRK10993 161 WTAYGGSYIYSNGgfrDDIGTFPDGERGIGYKQRFKMPYIGLTGSYRYDDFEFGGLLKYSGWVSASDNDEHYLRNLTFRD 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446638663 238 KTENSRYYGASIDAGYYITSNAKIFAEFAYSKYEEGKGGTQIIDKTSGDTAYFgGDAAGIANNNYTVTAGLQYRF 312
Cdd:PRK10993 241 KFKNSPYYSASINAGYYVTPNAKLYVEGAYNRYFEGKGDTQIYDHATGTSSYF-KDAAGIENQNYTVTAGLKYRF 314
PRK12580 PRK12580
omptin family plasminogen activator Pla;
1-312 4.54e-165

omptin family plasminogen activator Pla;


Pssm-ID: 79055  Cd Length: 312  Bit Score: 461.52  E-value: 4.54e-165
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663   1 MKKHAIAVMMIAVFSESVYAESTLFIPDVSPDSVTTSLSVGVLNGKSRELVYDTDTGRKISQLDWKIKNVATLQGDLSWE 80
Cdd:PRK12580   1 MKKSSIVATIITILSGSANAASSQLIPNISPDSFTVAASTGMLSGKSHEMLYDAETGRKISQLDWKIKNVAILKGDISWD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  81 PYSFMTLDARGWTSLASGSGHMVDHDWMSSEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRFS 160
Cdd:PRK12580  81 PYSFLTLNARGWTSLASGSGNMDDYDWMNENQSEWTDHSSHPATNVNHANEYDLNVKGWLLQDENYKAGITAGYQETRFS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663 161 WTARGGSYIYDNGRYIGNFPHGVRGIGYSQRFEMPYIGLAGDYRINDFECNVLFKYSDWVNAHDNDEHYMRKLTFREKTE 240
Cdd:PRK12580 161 WTATGGSYSYNNGAYTGNFPKGVRVIGYNQRFSMPYIGLAGQYRINDFELNALFKFSDWVRAHDNDEHYMRDLTFREKTS 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446638663 241 NSRYYGASIDAGYYITSNAKIFAEFAYSKYEEGKGGTQIIDKTSGDTAYFGGDAAGIANNNYTVTAGLQYRF 312
Cdd:PRK12580 241 GSRYYGTVINAGYYVTPNAKVFAEFTYSKYDEGKGGTQTIDKNSGDSVSIGGDAAGISNKNYTVTAGLQYRF 312
Omptin pfam01278
Omptin family; The omptin family is a family of serine proteases.
 30-312 2.06e-164

Omptin family; The omptin family is a family of serine proteases.


Pssm-ID: 426174  Cd Length: 282  Bit Score: 458.36  E-value: 2.06e-164
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663   30 SPDSVTTSLSVGVLNGKSRELVYDTDTGRKISQLDWKIKNVATLQGDLSWEPYSFMTLDARGWTSLASGSGHMVDHDWMS 109
Cdd:pfam01278   1 TPDNFSLSTSLGVLSGKAKEYVYDPETGRKLSQLDWKIKNAAIIKGEIEWDITPRLTLSASGWTTLASGSGVMDDYDWLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  110 SEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRFSWTARGGSYIYDNGRYIGNFPHGVRGIGYS 189
Cdd:pfam01278  81 PNQPTWTDWSHHPDTQLNYANEADLNAKGWLLQQNNYRLGALAGYQETRFSWTARGGSYSYNNGTDIGSFPDGVRGIGYK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  190 QRFEMPYIGLAGDYRINDFECNVLFKYSDWVNAHDNDEHYMRKLTFREKTENSRYYGASIDAGYYITSNAKIFAEFAYSK 269
Cdd:pfam01278 161 QRFKMPYIGLAGSYRINNFEFNALLKYSPWVRARDNDNHYLRSLTFKDKSKNSNYYSLSINAGYYVTPNAKLFLEAAWNR 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 446638663  270 YEEGKGGTQIIDKTSGDTAYFgGDAAGIANNNYTVTAGLQYRF 312
Cdd:pfam01278 241 YSNGKGDTTILDNRTGTSSVG-ENSAGIENQNYTLTVGLQYRF 282
OmpT COG4571
Outer membrane protease [Cell wall/membrane/envelope biogenesis];
1-312 5.54e-159

Outer membrane protease [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443628  Cd Length: 315  Bit Score: 445.97  E-value: 5.54e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663   1 MKKHAIAV-MMIAVFSESVYAESTLFIPDVSPDSVTTSLSVGVLNGKSRELVYDTDTGRKISQLDWKIKNVATLQGDLSW 79
Cdd:COG4571    1 MKKKLLVAlFLLAPLALPALANAATVEPEFTPDSVSFSLSLGVLSGESKEYVYDPDGGRKLSQLDWKIDNAPIIKGGLSW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663  80 EPYSFMTLDARGWTSLASGSGHMVDHDWMSSEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRF 159
Cdd:COG4571   81 DPLPWLSLGASGWTTLGSGSGYMDDYDWLNPGQTDWTDWSSHPKTRLNYANEFDLNAKGWLLKENNYSLGVLAGYQEDRF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446638663 160 SWTARGGSYIYDNG---RYIGNFPHGVRGIGYSQRFEMPYIGLAGDYRINDFECNVLFKYSDWVNAHDNDEHYMRKLTFR 236
Cdd:COG4571  161 SWTARGGSYIYSDNgfrDDVGTFPDGEKGISYKQRFKVPYIGLTGSYRYGNWEFGGLLKYSPWVRARDNDHHYLRDLTFK 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446638663 237 EKTENSRYYGASIDAGYYITSNAKIFAEFAYSKYEEGKGGTQIIDKTSGDTAYfGGDAAGIANNNYTVTAGLQYRF 312
Cdd:COG4571  241 DKFKNSNYYSLSLNAGYYVTPNLKFFVEASYSRYTEAKGDTTIYDLTTGTSSY-GGDAAGIDNYSYTVSLGLKYRF 315
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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