|
Name |
Accession |
Description |
Interval |
E-value |
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-228 |
1.91e-105 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 304.66 E-value: 1.91e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSMdGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEA 80
Cdd:COG1136 1 MSPLLELRNLTKSYGT-GEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLRLTEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRA 160
Cdd:COG1136 80 LARLRRRHIGFVFQFFNLLPELTALENVALPLLLAG-VSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 161 LINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAKTERILFMADGEIVSEIQ 228
Cdd:COG1136 159 LVNRPKLILADEPTGNLDSKTGEEVLELLRELNReLGTTIVMVTHDPELAARADRVIRLRDGRIVSDER 227
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
5-223 |
3.05e-95 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 278.22 E-value: 3.05e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMdGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:cd03255 1 IELKNLSKTYGG-GGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03255 80 RRRHIGFVFQSFNLLPDLTALENVELPLLLAG-VPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALAND 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAKTERILFMADGEI 223
Cdd:cd03255 159 PKIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDPELAEYADRIIELRDGKI 218
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
4-226 |
9.39e-68 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 209.21 E-value: 9.39e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:COG4181 8 IIELRGLTKTVG-TGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARAR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRLTEIGFIFQQSNLLRNLNLFDNIILSAYLAkceSKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALIN 163
Cdd:COG4181 87 LRARHVGFVFQSFQLLPTLTALENVMLPLELA---GRRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFAT 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:COG4181 164 EPAILFADEPTGNLDAATGEQIIDLLFELNRErGTTLVLVTHDPALAARCDRVLRLRAGRLVED 227
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
4-230 |
3.68e-64 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 199.51 E-value: 3.68e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgnTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:COG2884 1 MIRFENVSKRYP----GGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRLTeIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALIN 163
Cdd:COG2884 77 LRRR-IGVVFQDFRLLPDRTVYENVALPLRVTG-KSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVN 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIVSEIQLG 230
Cdd:COG2884 155 RPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLElVDRMPKRVLELEDGRLVRDEARG 222
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
4-226 |
4.81e-64 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 199.73 E-value: 4.81e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:cd03258 1 MIELKNVSKVFG-DTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALIN 163
Cdd:cd03258 80 AR-RRIGMIFQHFNLLSSRTVFENVALPLEIAG-VPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALAN 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:cd03258 158 NPKVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRiCDRVAVMEKGEVVEE 222
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
4-224 |
1.21e-63 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 198.68 E-value: 1.21e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScMKEEALAK 83
Cdd:COG1126 1 MIEIENLHKSF---GDL--EVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLT-DSKKDINK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALIN 163
Cdd:COG1126 75 LR-RKVGMVFQQFNLFPHLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAM 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV----KVAaktERILFMADGEIV 224
Cdd:COG1126 154 EPKVMLFDEPTSALDPELVGEVLDVMRDLAKEGMTMVVVTHEMgfarEVA---DRVVFMDGGRIV 215
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
5-223 |
3.71e-62 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 193.90 E-value: 3.71e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScMKEEALAKL 84
Cdd:cd03262 1 IEIKNLHKSFG-----DFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLT-DDKKNINEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03262 75 R-QKVGMVFQQFNLFPHLTVLENITLAPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMN 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEI 223
Cdd:cd03262 154 PKVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREvADRVIFMDDGRI 213
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
3-224 |
1.11e-60 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 191.42 E-value: 1.11e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 3 KILEVKQVNKTYsmDGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALA 82
Cdd:COG3638 1 PMLELRNLSKRY--PGGT--PALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KLRlTEIGFIFQQSNLLRNLNLFDNIILSA--------YLAKCESKKIVNkRALELMENMGISDIASHYITEASGGQLQR 154
Cdd:COG3638 77 RLR-RRIGMIFQQFNLVPRLSVLTNVLAGRlgrtstwrSLLGLFPPEDRE-RALEALERVGLADKAYQRADQLSGGQQQR 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 155 VSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:COG3638 155 VAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAReDGITVVVNLHQVDLARRyADRIIGLRDGRVV 226
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
4-224 |
9.04e-60 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 192.21 E-value: 9.04e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:COG1135 1 MIELENLSKTFPTKGGP-VTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRLtEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVSICRALIN 163
Cdd:COG1135 80 ARR-KIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEI-RKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALAN 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAKT-ERILFMADGEIV 224
Cdd:COG1135 158 NPKVLLCDEATSALDPETTRSILDLLKDINRElGLTIVLITHEMDVVRRIcDRVAVLENGRIV 220
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
4-224 |
1.43e-59 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 188.66 E-value: 1.43e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:TIGR02315 1 MLEVENLSKVY----PNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVN-------KRALELMENMGISDIASHYITEASGGQLQRVS 156
Cdd:TIGR02315 77 LR-RRIGMIFQHYNLIERLTVLENVLHGRLGYKPTWRSLLGrfseedkERALSALERVGLADKAYQRADQLSGGQQQRVA 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:TIGR02315 156 IARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEdGITVIINLHQVDLAKKyADRIVGLKAGEIV 225
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-242 |
4.54e-58 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 185.29 E-value: 4.54e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSMDGNTnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCmkeea 80
Cdd:COG1116 4 AAPALELRGVSKRFPTGGGG-VTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTG----- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 laklRLTEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRA 160
Cdd:COG1116 78 ----PGPDRGVVFQEPALLPWLTVLDNVALGLELRG-VPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 161 LINNPNIIFADEPTGAL-NLksTEEVMQ-ILLNI-NRGGTTIMLVTHDVkvaakTE------RILFMAD--GEIVSEIQ- 228
Cdd:COG1116 153 LANDPEVLLMDEPFGALdAL--TRERLQdELLRLwQETGKTVLFVTHDV-----DEavfladRVVVLSArpGRIVEEIDv 225
|
250
....*....|....*
gi 446644341 229 -LGKLRNDDLKAREE 242
Cdd:COG1116 226 dLPRPRDRELRTSPE 240
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-225 |
7.63e-58 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 194.56 E-value: 7.63e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLyNISG-MDQMSSGSVKIDSKELSCMKEE 79
Cdd:PRK10535 1 MTALLELKDIRRSYP-SGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLM-NILGcLDKPTSGTYRVAGQDVATLDAD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 ALAKLRLTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKiVNKRALELMENMGISDIASHYITEASGGQLQRVSICR 159
Cdd:PRK10535 79 ALAQLRREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQ-RLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIAR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 160 ALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIVS 225
Cdd:PRK10535 158 ALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVR 223
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
5-224 |
2.46e-57 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 182.77 E-value: 2.46e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:cd03256 1 IEVENLSKTY----PNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNLLRNLNLFDNIiLSAYLAKCES--------KKIVNKRALELMENMGISDIASHYITEASGGQLQRVS 156
Cdd:cd03256 77 R-RQIGMIFQQFNLIERLSVLENV-LSGRLGRRSTwrslfglfPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:cd03256 155 IARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREeGITVIVSLHQVDLAREyADRIVGLKDGRIV 224
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
5-227 |
6.02e-57 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 181.13 E-value: 6.02e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCmkeealakl 84
Cdd:cd03293 1 LEVRNVSKTYG-GGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTG--------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIGFIFQQSNLLRNLNLFDNIILsAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03293 71 PGPDRGYVFQQDALLPWLTVLDNVAL-GLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVD 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAakteriLFMAD---------GEIVSEI 227
Cdd:cd03293 150 PDVLLLDEPFSALDALTREQLQEELLDIwRETGKTVLLVTHDIDEA------VFLADrvvvlsarpGRIVAEV 216
|
|
| ABC_ATP_DarD |
NF038007 |
darobactin export ABC transporter ATP-binding protein; |
24-223 |
1.45e-55 |
|
darobactin export ABC transporter ATP-binding protein;
Pssm-ID: 411600 [Multi-domain] Cd Length: 218 Bit Score: 177.60 E-value: 1.45e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLyNISGM-DQMSSGSVKIDSKELSCMKEEALAKLRLTEIGFIFQQSNLLRNL 102
Cdd:NF038007 20 VLNHLNFSVEKGDFVSIMGPSGSGKSTLL-NIIGMfDSLDSGSLTLAGKEVTNLSYSQKIILRRELIGYIFQSFNLIPHL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 103 NLFDNIILS-AY--LAKCESKKIVNkralELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNL 179
Cdd:NF038007 99 SIFDNVALPlKYrgVAKKERIERVN----QVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSNPALLLADEPTGNLDS 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446644341 180 KSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEI 223
Cdd:NF038007 175 KNARAVLQQLKYINQKGTTIIMVTHSDEASTYGNRIINMKDGKL 218
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
4-222 |
4.08e-55 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 176.28 E-value: 4.08e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:TIGR02673 1 MIEFHNVSKAY----PGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLPL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVSICRALIN 163
Cdd:TIGR02673 77 LR-RRIGVVFQDFRLLPDRTVYENVALPLEVRGKKEREI-QRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVN 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGE 222
Cdd:TIGR02673 155 SPPLLLADEPTGNLDPDLSERILDLLKRLNKRGTTVIVATHDLSLVDRVaHRVIILDDGR 214
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
4-224 |
1.25e-54 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 175.39 E-value: 1.25e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTNyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEaLAK 83
Cdd:cd03257 1 LLEVKNLSVSFPTGGGSV-KALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRR-LRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRLTEIGFIFQ--QSNLLRNLNLFDNIILSAYLAKCESKK-IVNKRALELMENMGIS-DIASHYITEASGGQLQRVSICR 159
Cdd:cd03257 79 IRRKEIQMVFQdpMSSLNPRMTIGEQIAEPLRIHGKLSKKeARKEAVLLLLVGVGLPeEVLNRYPHELSGGQRQRVAIAR 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 160 ALINNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:cd03257 159 ALALNPKLLIADEPTSALDVSVQAQILDLLKKLqEELGLTLLFITHDLGVVAKiADRVAVMYAGKIV 225
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
4-224 |
9.06e-54 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 180.87 E-value: 9.06e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:COG1123 260 LLEVRNLSKRYPVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRE 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlTEIGFIFQ--QSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGIS-DIASHYITEASGGQLQRVSICRA 160
Cdd:COG1123 340 LR-RRVQMVFQdpYSSLNPRMTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPpDLADRYPHELSGGQRQRVAIARA 418
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 161 LINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:COG1123 419 LALEPKLLILDEPTSALDVSVQAQILNLLRDLQReLGLTYLFISHDLAVVRYiADRVAVMYDGRIV 484
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
5-226 |
2.81e-53 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 171.75 E-value: 2.81e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscmKEEALAKL 84
Cdd:COG1122 1 IELENLSFSY----PGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDI---TKKNLREL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNL--------------LRNLNLfdniilsaylakceSKKIVNKRALELMENMGISDIASHYITEASGG 150
Cdd:COG1122 74 R-RKVGLVFQNPDDqlfaptveedvafgPENLGL--------------PREEIRERVEEALELVGLEHLADRPPHELSGG 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 151 QLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:COG1122 139 QKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAElADRVIVLDDGRIVAD 215
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
5-224 |
1.11e-52 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 170.01 E-value: 1.11e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEalakl 84
Cdd:cd03259 1 LELKGLSKTY---GSV--RALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPE----- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rLTEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03259 71 -RRNIGMVFQDYALFPHLTVAENIAFGLKLRG-VPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALARE 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:cd03259 149 PSLLLLDEPLSALDAKLREELREELKELqRELGITTIYVTHDQEEALAlADRIAVMNEGRIV 210
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
2-229 |
1.30e-52 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 170.38 E-value: 1.30e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNKTYSmDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAL 81
Cdd:PRK11629 3 KILLQCDNLCKRYQ-EGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKLRLTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVSICRAL 161
Cdd:PRK11629 82 AELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEI-NSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEVMQILLNIN-RGGTTIMLVTHDVKVAAKTERILFMADGEIVSEIQL 229
Cdd:PRK11629 161 VNNPRLVLADEPTGNLDARNADSIFQLLGELNrLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAELSL 229
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
5-223 |
1.42e-52 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 169.90 E-value: 1.42e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgnTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:cd03292 1 IEFINVTKTYP----NGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03292 77 R-RKIGVVFQDFRLLPDRNVYENVAFALEVTG-VPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNS 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTE-RILFMADGEI 223
Cdd:cd03292 155 PTILIADEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRhRVIALERGKL 214
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-224 |
2.97e-52 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 169.77 E-value: 2.97e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEA 80
Cdd:COG1127 2 SEPMIEVRNLTKSF---GDR--VVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLRLtEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRA 160
Cdd:COG1127 77 LYELRR-RIGMLFQGGALFDSLTVFENVAFPLREHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 161 LINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAKT-ERILFMADGEIV 224
Cdd:COG1127 156 LALDPEILLYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIaDRVAVLADGKII 221
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
5-236 |
1.08e-51 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 168.06 E-value: 1.08e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:cd03261 1 IELRGLTKSF---GGR--TVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNLLRNLNLFDNII--LSAYLAKCESkkIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALI 162
Cdd:cd03261 76 R-RRMGMLFQSGALFDSLTVFENVAfpLREHTRLSEE--EIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 163 NNPNIIFADEPTGALNLKSTEEVMQILLNINR--GGTTIMlVTHDVKVAAKT-ERILFMADGEIVSEIQLGKLRNDD 236
Cdd:cd03261 153 LDPELLLYDEPTAGLDPIASGVIDDLIRSLKKelGLTSIM-VTHDLDTAFAIaDRIAVLYDGKIVAEGTPEELRASD 228
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
6-222 |
2.46e-51 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 166.49 E-value: 2.46e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 6 EVKQVNKTYsmdGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlr 85
Cdd:cd03225 1 ELKNLSFSY---PDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRR-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 86 ltEIGFIFQQSNL-LRNLNLFDNIILSAyLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03225 76 --KVGLVFQNPDDqFFGPTVEEEVAFGL-ENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMD 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGE 222
Cdd:cd03225 153 PDILLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDlLLELADRVIVLEDGK 211
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
2-226 |
6.49e-51 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 166.11 E-value: 6.49e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNKTYSmDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAL 81
Cdd:PRK10584 4 ENIVEVHHLKKSVG-QGEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEAR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKLRLTEIGFIFQQSNLLRNLNLFDNIILSAYLaKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRAL 161
Cdd:PRK10584 83 AKLRAKHVGFVFQSFMLIPTLNALENVELPALL-RGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAF 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:PRK10584 162 NGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREhGTTLILVTHDLQLAARCDRRLRLVNGQLQEE 227
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
5-237 |
7.21e-51 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 166.01 E-value: 7.21e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKl 84
Cdd:COG1131 1 IEVRGLTKRY---GDK--TALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRR- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNLLRNLNLFDNIILSAYLAKCeSKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:COG1131 75 ----IGYVPQEPALYPDLTVRENLRFFARLYGL-PRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHD 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGEIVSEIQLGKLRNDDL 237
Cdd:COG1131 150 PELLILDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLcDRVAIIDKGRIVADGTPDELKARLL 223
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
5-222 |
8.81e-49 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 158.89 E-value: 8.81e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscMKEEALAKL 84
Cdd:cd03229 1 LELKNVSKRYG-----QKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDL--TDLEDELPP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIGFIFQQSNLLRNLNLFDNIILsaylakceskkivnkrALelmenmgisdiashyiteaSGGQLQRVSICRALINN 164
Cdd:cd03229 74 LRRRIGMVFQDFALFPHLTVLENIAL----------------GL-------------------SGGQQQRVALARALAMD 118
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNIN-RGGTTIMLVTHDVKVAAK-TERILFMADGE 222
Cdd:cd03229 119 PDVLLLDEPTSALDPITRREVRALLKSLQaQLGITVVLVTHDLDEAARlADRVVVLRDGK 178
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
6-224 |
1.25e-48 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 163.43 E-value: 1.25e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 6 EVKQVNKTYSMDGNTnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLR 85
Cdd:PRK11153 3 ELKNISKVFPQGGRT-IHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 86 LtEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNP 165
Cdd:PRK11153 82 R-QIGMIFQHFNLLSSRTVFDNVALPLELAG-TPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNP 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 166 NIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTH--DVkVAAKTERILFMADGEIV 224
Cdd:PRK11153 160 KVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHemDV-VKRICDRVAVIDAGRLV 220
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
7-218 |
1.35e-48 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 159.32 E-value: 1.35e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 7 VKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRL 86
Cdd:TIGR03608 1 LKNISKKFG-----DKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 87 TEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPN 166
Cdd:TIGR03608 76 EKLGYLFQNFALIENETVEENLDLGLKYKK-LSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPP 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446644341 167 IIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFM 218
Cdd:TIGR03608 155 LILADEPTGSLDPKNRDEVLDLLLELNDEGKTIIIVTHDPEVAKQADRVIEL 206
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-224 |
8.33e-48 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 165.08 E-value: 8.33e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSMDGNtnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGM---DQMSSGSVKIDSKELSCMK 77
Cdd:COG1123 1 MTPLLEVRDLSVRYPGGDV---PAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLlphGGRISGEVLLDGRDLLELS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 78 EealaKLRLTEIGFIFQQ-SNLLRNLNLFDNIILsAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVS 156
Cdd:COG1123 78 E----ALRGRRIGMVFQDpMTQLNPVTVGDQIAE-ALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:COG1123 153 IAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQReRGTTVLLITHDLGVVAEiADRVVVMDDGRIV 222
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
4-226 |
2.98e-47 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 157.13 E-value: 2.98e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsmDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:COG1120 1 MLEAENLSVGY--GGRP---VLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LrlteIGFIFQQSNLLRNLNLFDNIILSAY--------LAKcESKKIVNkRALELmenMGISDIASHYITEASGGQLQRV 155
Cdd:COG1120 76 R----IAYVPQEPPAPFGLTVRELVALGRYphlglfgrPSA-EDREAVE-EALER---TGLEHLADRPVDELSGGERQRV 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 156 SICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAKT-ERILFMADGEIVSE 226
Cdd:COG1120 147 LIARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARErGRTVVMVLHDLNLAARYaDRLVLLKDGRIVAQ 219
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-230 |
6.13e-47 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 159.11 E-value: 6.13e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEA 80
Cdd:COG3842 2 AMPALELENVSKRY---GDV--TALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 laklRltEIGFIFQQSNLLRNLNLFDNIilsAY-L-AKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSIC 158
Cdd:COG3842 77 ----R--NVGMVFQDYALFPHLTVAENV---AFgLrMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 159 RALINNPNIIFADEPTGALNLKSTEEvMQILL-NINR--GGTTIMlVTHDvkvaaKTE------RILFMADGEIVseiQL 229
Cdd:COG3842 148 RALAPEPRVLLLDEPLSALDAKLREE-MREELrRLQRelGITFIY-VTHD-----QEEalaladRIAVMNDGRIE---QV 217
|
.
gi 446644341 230 G 230
Cdd:COG3842 218 G 218
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
4-223 |
1.21e-46 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 155.25 E-value: 1.21e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsmdGNTNyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSkeLSCMKEEALAK 83
Cdd:PRK09493 1 MIEFKNVSKHF---GPTQ--VLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDG--LKVNDPKVDER 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRLTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALIN 163
Cdd:PRK09493 74 LIRQEAGMVFQQFYLFPHLTALENVMFGPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAV 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGEI 223
Cdd:PRK09493 154 KPKLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVaSRLIFIDKGRI 214
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-223 |
4.25e-46 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 154.09 E-value: 4.25e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVnkTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscmkeea 80
Cdd:COG1121 3 MMPAIELENL--TVSYGGRP---VLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPP------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 laKLRLTEIGFIFQQSNLLRNLNL--FDnIILSAYLAKCESKKIVNK----RALELMENMGISDIASHYITEASGGQLQR 154
Cdd:COG1121 71 --RRARRRIGYVPQRAEVDWDFPItvRD-VVLMGRYGRRGLFRRPSRadreAVDEALERVGLEDLADRPIGELSGGQQQR 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 155 VSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEI 223
Cdd:COG1121 148 VLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLgAVREYFDRVLLLNRGLV 217
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
25-231 |
5.33e-46 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 154.72 E-value: 5.33e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRLTEIGFIFQQSNLLRNLNL 104
Cdd:cd03294 40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRKKISMVFQSFALLPHRTV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 105 FDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALN-LKSTE 183
Cdd:cd03294 120 LENVAFGLEVQG-VPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDpLIRRE 198
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446644341 184 evMQ-ILLNINRG-GTTIMLVTHDVKVAAKT-ERILFMADGEIVseiQLGK 231
Cdd:cd03294 199 --MQdELLRLQAElQKTIVFITHDLDEALRLgDRIAIMKDGRLV---QVGT 244
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
5-235 |
6.78e-46 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 153.42 E-value: 6.78e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMdGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkeEALAKL 84
Cdd:COG1124 2 LEVRNLSVSYGQ-GGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVT----RRRRKA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIGFIFQQSnlLRNLNLFDNI--ILSAYLaKCESKKIVNKRALELMENMGI-SDIASHYITEASGGQLQRVSICRAL 161
Cdd:COG1124 77 FRRRVQMVFQDP--YASLHPRHTVdrILAEPL-RIHGLPDREERIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARAL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAK-TERILFMADGEIVSEIQLGKLRND 235
Cdd:COG1124 154 ILEPELLLLDEPTSALDVSVQAEILNLLKDLREeRGLTYLFVSHDLAVVAHlCDRVAVMQNGRIVEELTVADLLAG 229
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
4-224 |
1.65e-44 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 152.13 E-value: 1.65e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQ---MSSGSVKIDSKELSCMKEEA 80
Cdd:COG0444 1 LLEVRNLKVYFPTRRGV-VKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEILFDGEDLLKLSEKE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLRLTEIGFIFQ---QSnllrnLN----LFDNIILSAYLAKCESKKIVNKRALELMENMGISD---IASHYITEASGG 150
Cdd:COG0444 80 LRKIRGREIQMIFQdpmTS-----LNpvmtVGDQIAEPLRIHGGLSKAEARERAIELLERVGLPDperRLDRYPHELSGG 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 151 QLQRVSICRALINNPNIIFADEPTGALNLkSTE-EVMQILLNINRG-GTTIMLVTHDVKVAAKT-ERILFMADGEIV 224
Cdd:COG0444 155 MRQRVMIARALALEPKLLIADEPTTALDV-TIQaQILNLLKDLQRElGLAILFITHDLGVVAEIaDRVAVMYAGRIV 230
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
5-230 |
8.30e-44 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 147.77 E-value: 8.30e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscmkeealAKL 84
Cdd:cd03300 1 IELENVSKFYG-----GFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI--------TNL 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTE--IGFIFQQSNLLRNLNLFDNIILSAYLAKCeSKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALI 162
Cdd:cd03300 68 PPHKrpVNTVFQNYALFPHLTVFENIAFGLRLKKL-PKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALV 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 163 NNPNIIFADEPTGALNLKSTEEvMQI-LLNINRG-GTTIMLVTHDVKVA-AKTERILFMADGEIVseiQLG 230
Cdd:cd03300 147 NEPKVLLLDEPLGALDLKLRKD-MQLeLKRLQKElGITFVFVTHDQEEAlTMSDRIAVMNKGKIQ---QIG 213
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
5-230 |
1.23e-43 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 147.45 E-value: 1.23e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkEEALAKL 84
Cdd:cd03295 1 IEFENVTKRY----GGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIR---EQDPVEL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELME--NMGISDIASHYITEASGGQLQRVSICRALI 162
Cdd:cd03295 74 R-RKIGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKI-RERADELLAlvGLDPAEFADRYPHELSGGQQQRVGVARALA 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 163 NNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIVseiQLG 230
Cdd:cd03295 152 ADPPLLLMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRlADRIAIMKNGEIV---QVG 218
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
5-223 |
1.35e-43 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 146.50 E-value: 1.35e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAlakL 84
Cdd:COG4619 1 LELEGLSFRVG-----GKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPE---W 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNLLRNlNLFDNIILSAYLAKcesKKIVNKRALELMENMGIS-DIASHYITEASGGQLQRVSICRALIN 163
Cdd:COG4619 73 R-RQVAYVPQEPALWGG-TVRDNLPFPFQLRE---RKFDRERALELLERLGLPpDILDKPVERLSGGERQRLALIRALLL 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLN-INRGGTTIMLVTHDVKVAAK-TERILFMADGEI 223
Cdd:COG4619 148 QPDVLLLDEPTSALDPENTRRVEELLREyLAEEGRAVLWVSHDPEQIERvADRVLTLEAGRL 209
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
5-224 |
7.14e-43 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 145.54 E-value: 7.14e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSC---MKEEAL 81
Cdd:COG4161 3 IQLKNINCFYG-----SHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDFsqkPSEKAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKLRlTEIGFIFQQSNLLRNLNLFDNIILsaylAKCE----SKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSI 157
Cdd:COG4161 78 RLLR-QKVGMVFQQYNLWPHLTVMENLIE----APCKvlglSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAI 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 158 CRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGEIV 224
Cdd:COG4161 153 ARALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFARKVaSQVVYMEKGRII 220
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
6-224 |
1.41e-42 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 143.83 E-value: 1.41e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 6 EVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEalaklr 85
Cdd:cd03235 1 EVEDLTVSYG-----GHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKR------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 86 lteIGFIFQQSNLLRNLNL--FDnIILSAYLAKCESKKIVNK----RALELMENMGISDIASHYITEASGGQLQRVSICR 159
Cdd:cd03235 70 ---IGYVPQRRSIDRDFPIsvRD-VVLMGLYGHKGLFRRLSKadkaKVDEALERVGLSELADRQIGELSGGQQQRVLLAR 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 160 ALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMaDGEIV 224
Cdd:cd03235 146 ALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLgLVLEYFDRVLLL-NRTVV 210
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
5-226 |
2.38e-42 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 144.12 E-value: 2.38e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmDGntnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:cd03219 1 LEVRGLTKRF--GG---LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlteIGFIFQQSNLLRNLNLFDNIILSAYLAK---------CESKKIVNKRALELMENMGISDIASHYITEASGGQLQRV 155
Cdd:cd03219 76 G---IGRTFQIPRLFPELTVLENVMVAAQARTgsglllaraRREEREARERAEELLERVGLADLADRPAGELSYGQQRRL 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 156 SICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIVSE 226
Cdd:cd03219 153 EIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDvVMSLADRVTVLDQGRVIAE 224
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
5-224 |
4.29e-42 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 143.09 E-value: 4.29e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdgnTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQM-----SSGSVKIDSKELSCMKEE 79
Cdd:cd03260 1 IELRDLNVYY-----GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDIYDLDVD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 ALAkLRlTEIGFIFQQSNLLRnLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASH--YITEASGGQLQRVSI 157
Cdd:cd03260 76 VLE-LR-RRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKDrlHALGLSGGQQQRLCL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 158 CRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRgGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:cd03260 153 ARALANEPEVLLLDEPTSALDPISTAKIEELIAELKK-EYTIVIVTHNMQQAARvADRTAFLLNGRLV 219
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
25-174 |
1.25e-41 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 139.32 E-value: 1.25e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrltEIGFIFQQSNLLRNLNL 104
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRK----EIGYVFQDPQLFPRLTV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 105 FDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEA----SGGQLQRVSICRALINNPNIIFADEPT 174
Cdd:pfam00005 77 RENLRLGLLLKG-LSKREKDARAEEALEKLGLGDLADRPVGERpgtlSGGQRQRVAIARALLTKPKLLLLDEPT 149
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
5-223 |
1.96e-41 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 139.84 E-value: 1.96e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmKEEALAKL 84
Cdd:cd03230 1 IEVRNLSKRYG-----KKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIK--KEPEEVKR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlteIGFIFQQSNLLRNLNLFDNIILsaylakceskkivnkralelmenmgisdiashyiteaSGGQLQRVSICRALINN 164
Cdd:cd03230 74 R---IGYLPEEPSLYENLTVRENLKL-------------------------------------SGGMKQRLALAQALLHD 113
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGEI 223
Cdd:cd03230 114 PELLILDEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLcDRVAILNNGRI 173
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
5-224 |
2.28e-41 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 144.52 E-value: 2.28e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDskelscmKEEALAKL 84
Cdd:COG1118 3 IEVRNISKRFG-----SFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLN-------GRDLFTNL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTE--IGFIFQQSNLLRNLNLFDNIilsAY-L-AKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRA 160
Cdd:COG1118 71 PPRErrVGFVFQHYALFPHMTVAENI---AFgLrVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARA 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 161 LINNPNIIFADEPTGALNLKSTEEVMQILLNI--NRGGTTImLVTHDV----KVAaktERILFMADGEIV 224
Cdd:COG1118 148 LAVEPEVLLLDEPFGALDAKVRKELRRWLRRLhdELGGTTV-FVTHDQeealELA---DRVVVMNQGRIE 213
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
6-226 |
2.35e-41 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 139.88 E-value: 2.35e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 6 EVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLr 85
Cdd:cd03214 1 EVENLSVGYG-----GRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARK- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 86 lteIGFIFQqsnllrnlnlfdniilsaylakceskkivnkraleLMENMGISDIASHYITEASGGQLQRVSICRALINNP 165
Cdd:cd03214 75 ---IAYVPQ-----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEP 116
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 166 NIIFADEPTGALNLKSTEEVMQIL--LNINRGGTTIMlVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:cd03214 117 PILLLDEPTSHLDIAHQIELLELLrrLARERGKTVVM-VLHDLNLAARyADRVILLKDGRIVAQ 179
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
5-224 |
3.80e-40 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 138.61 E-value: 3.80e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKEL---SCMKEEAL 81
Cdd:PRK11124 3 IQLNGINCFYG-----AHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdfsKTPSDKAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKLRlTEIGFIFQQSNLLRNLNLFDNIILsaylAKCE----SKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSI 157
Cdd:PRK11124 78 RELR-RNVGMVFQQYNLWPHLTVQQNLIE----APCRvlglSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAI 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 158 CRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGEIV 224
Cdd:PRK11124 153 ARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTaSRVVYMENGHIV 220
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
5-219 |
8.79e-40 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 138.07 E-value: 8.79e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmKEEAlakl 84
Cdd:COG4525 4 LTVRHVSVRYP-GGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVT--GPGA---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rltEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:COG4525 77 ---DRGVVFQKDALLPWLNVLDNVAFGLRLRG-VPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAAD 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVkvaaktERILFMA 219
Cdd:COG4525 153 PRFLLMDEPFGALDALTREQMQELLLDVwQRTGKGVFLITHSV------EEALFLA 202
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
5-230 |
8.87e-40 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 136.62 E-value: 8.87e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkeEALAKL 84
Cdd:cd03301 1 VELENVTKRFG-----NVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVT----DLPPKD 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RltEIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03301 72 R--DIAMVFQNYALYPHMTVYDNIAFGLKLRK-VPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVRE 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVA-AKTERILFMADGEIVseiQLG 230
Cdd:cd03301 149 PKVFLMDEPLSNLDAKLRVQMRAELKRLQQRlGTTTIYVTHDQVEAmTMADRIAVMNDGQIQ---QIG 213
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
5-226 |
1.08e-39 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 137.57 E-value: 1.08e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVK-----ID-SKELScmKE 78
Cdd:PRK11264 4 IEVKNLVKKFH--GQT---VLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRvgditIDtARSLS--QQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 79 EALAKLRLTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSIC 158
Cdd:PRK11264 77 KGLIRQLRQHVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 159 RALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK11264 157 RALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDvADRAIFMDQGRIVEQ 225
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
24-248 |
2.53e-38 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 133.62 E-value: 2.53e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAlaklrlTEIGFIFQQSNLLRNLN 103
Cdd:cd03299 14 KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEK------RDISYVPQNYALFPHMT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIilsAY--LAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKS 181
Cdd:cd03299 88 VYKNI---AYglKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRT 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 182 TEEVMQILLNINR-GGTTIMLVTHD-VKVAAKTERILFMADGEIvseIQLGKLRNDDLKAREEKLLNWL 248
Cdd:cd03299 165 KEKLREELKKIRKeFGVTVLHVTHDfEEAWALADKVAIMLNGKL---IQVGKPEEVFKKPKNEFVAEFL 230
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
5-222 |
3.18e-38 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 131.35 E-value: 3.18e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:cd03228 1 IEFKNVSFSY---PGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNLLrNLNLFDNIIlsaylakceskkivnkralelmenmgisdiashyiteaSGGQLQRVSICRALINN 164
Cdd:cd03228 78 ----IAYVPQDPFLF-SGTIRENIL--------------------------------------SGGQRQRIAIARALLRD 114
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGE 222
Cdd:cd03228 115 PPILILDEATSALDPETEALILEALRALAKGKTVIV-IAHRLSTIRDADRIIVLDDGR 171
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
5-230 |
4.58e-38 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 135.97 E-value: 4.58e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkeEALAKL 84
Cdd:COG3839 4 LELENVSKSY---GGV--EALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVT----DLPPKD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RltEIGFIFQQSNLLRNLNLFDNIilsAY---LAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRAL 161
Cdd:COG3839 75 R--NIAMVFQSYALYPHMTVYENI---AFplkLRK-VPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRAL 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 162 INNPNIIFADEPTGAL--NLKST--EEVMQILlniNRGGTTIMLVTHDvkvaaKTE------RILFMADGEIVseiQLG 230
Cdd:COG3839 149 VREPKVFLLDEPLSNLdaKLRVEmrAEIKRLH---RRLGTTTIYVTHD-----QVEamtladRIAVMNDGRIQ---QVG 216
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
5-230 |
9.68e-38 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 132.46 E-value: 9.68e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMkeealaKL 84
Cdd:cd03296 3 IEVRNVSKRFG-----DFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDV------PV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIGFIFQQSNLLRNLNLFDNIILSAYL---AKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRAL 161
Cdd:cd03296 72 QERNVGFVFQHYALFRHMTVFDNVAFGLRVkprSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARAL 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAK-TERILFMADGEIvseIQLG 230
Cdd:cd03296 152 AVEPKVLLLDEPFGALDAKVRKELRRWLRRLhDELHVTTVFVTHDQEEALEvADRVVVMNKGRI---EQVG 219
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
5-224 |
3.43e-37 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 131.80 E-value: 3.43e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:TIGR04521 1 IKLKNVSYIYQPGTPFEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQ--QSNL------------LRNLNLfdniilsaylakceSKKIVNKRALELMENMGIS-DIASHYITEASG 149
Cdd:TIGR04521 81 R-KKVGLVFQfpEHQLfeetvykdiafgPKNLGL--------------SEEEAEERVKEALELVGLDeEYLERSPFELSG 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 150 GQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:TIGR04521 146 GQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKeKGLTVILVTHSMEdVAEYADRVIVMHKGKIV 222
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
5-224 |
5.21e-37 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 137.66 E-value: 5.21e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNtnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscmKEEALAKL 84
Cdd:COG2274 474 IELENVSFRYPGDSP---PVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDL---RQIDPASL 547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNLLrNLNLFDNIILSAYLAkcESKKIVnkRALELMenmGISD-IASH------YITEA----SGGQLQ 153
Cdd:COG2274 548 R-RQIGVVLQDVFLF-SGTIRENITLGDPDA--TDEEII--EAARLA---GLHDfIEALpmgydtVVGEGgsnlSGGQRQ 618
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIV 224
Cdd:COG2274 619 RLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVII-IAHRLSTIRLADRIIVLDKGRIV 688
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
5-223 |
5.26e-37 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 133.29 E-value: 5.26e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTNyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKeealAKL 84
Cdd:PRK10851 3 IEIANIKKSF---GRTQ--VLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLH----ARD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RltEIGFIFQQSNLLRNLNLFDNIILS-AYLAKCE--SKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRAL 161
Cdd:PRK10851 74 R--KVGFVFQHYALFRHMTVFDNIAFGlTVLPRRErpNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARAL 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEI 223
Cdd:PRK10851 152 AVEPQILLLDEPFGALDAQVRKELRRWLRQLHEElKFTSVFVTHDQEEAMEvADRVVVMSQGNI 215
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
4-226 |
5.31e-37 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 130.93 E-value: 5.31e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsmDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLyN-ISGMDQMSSGSVKIDSKELSCMKEEALA 82
Cdd:COG0411 4 LLEVRGLTKRF--GGLV---AVDDVSLEVERGEIVGLIGPNGAGKTTLF-NlITGFYRPTSGRILFDGRDITGLPPHRIA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KLRL--TeigfiFQQSNLLRNLNLFDNIILSAYLAKCES--------------KKIVNKRALELMENMGISDIASHYITE 146
Cdd:COG0411 78 RLGIarT-----FQNPRLFPELTVLENVLVAAHARLGRGllaallrlprarreEREARERAEELLERVGLADRADEPAGN 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 147 ASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:COG0411 153 LSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDErGITILLIEHDMDLVMGlADRIVVLDFGRVI 232
|
..
gi 446644341 225 SE 226
Cdd:COG0411 233 AE 234
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
5-245 |
6.21e-37 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 130.36 E-value: 6.21e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKl 84
Cdd:COG4555 2 IEVENLSKKYG-----KVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARRQ- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:COG4555 76 ----IGVLPDERGLYDRLTVRENIRYFAELYG-LFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGEIVSEIQLGKLRNDDLKAREEK 243
Cdd:COG4555 151 PKVLLLDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALcDRVVILHKGKVVAQGSLDELREEIGEENLED 230
|
..
gi 446644341 244 LL 245
Cdd:COG4555 231 AF 232
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
5-235 |
1.98e-36 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 128.32 E-value: 1.98e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMdgntnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:cd03224 1 LEVENLNAGYGK-----SQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rltEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGisDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03224 76 ---GIGYVPEGRRIFPELTVEENLLLGAYARRRAKRKARLERVYELFPRLK--ERRKQLAGTLSGGEQQMLAIARALMSR 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSEIQLGKLRND 235
Cdd:cd03224 151 PKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEiADRAYVLERGRVVLEGTAAELLAD 222
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-223 |
2.26e-36 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 129.36 E-value: 2.26e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGM---DQMSSGSVKIDSKELSCMK 77
Cdd:PRK09984 1 MQTIIRVEKLAKTFN-----QHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgDKSAGSHIELLGRTVQREG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 78 EEA--LAKLRlTEIGFIFQQSNLLRNLNLFDNIILSA-----YLAKCES--KKIVNKRALELMENMGISDIASHYITEAS 148
Cdd:PRK09984 76 RLArdIRKSR-ANTGYIFQQFNLVNRLSVLENVLIGAlgstpFWRTCFSwfTREQKQRALQALTRVGMVHFAHQRVSTLS 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 149 GGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEI 223
Cdd:PRK09984 155 GGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRyCERIVALRQGHV 231
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
4-224 |
3.25e-36 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 128.07 E-value: 3.25e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsMDGNtnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:PRK10908 1 MIRFEHVSKAY-LGGR---QALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPF 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVSICRALIN 163
Cdd:PRK10908 77 LR-RQIGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDI-RRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVN 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:PRK10908 155 KPAVLLADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGlISRRSYRMLTLSDGHLH 216
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
5-223 |
4.54e-36 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 128.64 E-value: 4.54e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEalakL 84
Cdd:PRK11247 13 LLLNAVSKRYG-----ERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEARED----T 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLteigfIFQQSNLLRNLNLFDNIILSAylakcesKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:PRK11247 84 RL-----MFQDARLLPWKKVIDNVGLGL-------KGQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHR 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVA-AKTERILFMADGEI 223
Cdd:PRK11247 152 PGLLLLDEPLGALDALTRIEMQDLIESLwQQHGFTVLLVTHDVSEAvAMADRVLLIEEGKI 212
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-223 |
6.28e-36 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 130.84 E-value: 6.28e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNKTYsmDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAl 81
Cdd:PRK09452 12 SPLVELRGISKSF--DGKE---VISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAEN- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 aklrlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVSICRAL 161
Cdd:PRK09452 86 -----RHVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEI-TPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEvMQI-LLNINRG-GTTIMLVTHDVKVA-AKTERILFMADGEI 223
Cdd:PRK09452 160 VNKPKVLLLDESLSALDYKLRKQ-MQNeLKALQRKlGITFVFVTHDQEEAlTMSDRIVVMRDGRI 223
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
25-221 |
6.32e-36 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 127.20 E-value: 6.32e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKElscmkeealaklrLTEIG----FIFQQSNLLR 100
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQ-------------ITEPGpdrmVVFQNYSLLP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 NLNLFDNIILS-----AYLAKCESKKIVNkralELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTG 175
Cdd:TIGR01184 68 WLTVRENIALAvdrvlPDLSKSERRAIVE----EHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFG 143
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446644341 176 ALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAA-KTERILFMADG 221
Cdd:TIGR01184 144 ALDALTRGNLQEELMQIwEEHRVTVLMVTHDVDEALlLSDRVVMLTNG 191
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
6-222 |
9.99e-36 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 124.66 E-value: 9.99e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 6 EVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlr 85
Cdd:cd00267 1 EIENLSFRYG-----GRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRR-- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 86 ltEIGFIFQQSnllrnlnlfdniilsaylakceskkivnkralelmenmgisdiashyiteasGGQLQRVSICRALINNP 165
Cdd:cd00267 74 --RIGYVPQLS----------------------------------------------------GGQRQRVALARALLLNP 99
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 166 NIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGE 222
Cdd:cd00267 100 DLLLLDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELaADRVIVLKDGK 157
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
5-224 |
1.06e-35 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 126.47 E-value: 1.06e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAkl 84
Cdd:cd03263 1 LQIRNLTKTY---KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQ-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rltEIGFIFQQSNLLRNLNLFDNIILSAYLaKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03263 76 ---SLGYCPQFDALFDELTVREHLRFYARL-KGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGG 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNInRGGTTIMLVTHDVKVA-AKTERILFMADGEIV 224
Cdd:cd03263 152 PSVLLLDEPTSGLDPASRRAIWDLILEV-RKGRSIILTTHSMDEAeALCDRIAIMSDGKLR 211
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
5-226 |
9.11e-35 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 125.24 E-value: 9.11e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSkeLSCMKEEALAKL 84
Cdd:TIGR04520 1 IEVENVSFSYP---ESEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDG--LDTLDEENLWEI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSnllrnlnlfDNIILSAY-------------LAKCESKKIVNKrALELMenmGISDIASHYITEASGGQ 151
Cdd:TIGR04520 76 R-KKVGMVFQNP---------DNQFVGATveddvafglenlgVPREEMRKRVDE-ALKLV---GMEDFRDREPHLLSGGQ 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 152 LQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:TIGR04520 142 KQRVAIAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKeEGITVISITHDMEEAVLADRVIVMNKGKIVAE 217
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
5-223 |
2.11e-33 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 121.45 E-value: 2.11e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScMKEEA---- 80
Cdd:COG4598 9 LEVRDLHKSFG-----DLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIR-LKPDRdgel 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 -------LAKLRlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQ 153
Cdd:COG4598 83 vpadrrqLQRIR-TRLGMVFQSFNLWSHMTVLENVIEAPVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQ 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEI 223
Cdd:COG4598 162 RAAIARALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEEGRTMLVVTHEMGFARDvSSHVVFLHQGRI 232
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
15-224 |
3.54e-33 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 119.28 E-value: 3.54e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 15 SMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkeealAKLRLTEIGFIFQ 94
Cdd:cd03226 6 SFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIK-------AKERRKSIGYVMQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 95 QSNllRNL---NLFDNIILSAYLAkceSKKivNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFAD 171
Cdd:cd03226 79 DVD--YQLftdSVREELLLGLKEL---DAG--NEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFD 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446644341 172 EPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGEIV 224
Cdd:cd03226 152 EPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVcDRVLLLANGAIV 205
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
5-224 |
3.85e-33 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 126.03 E-value: 3.85e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNtnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:COG4988 337 IELEDVSFSYPGGRP----ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRRQ 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNLLrNLNLFDNIILSAYLAkceSKKIVnKRALELMenmGISD-IAS------HYITEA----SGGQLQ 153
Cdd:COG4988 413 ----IAWVPQNPYLF-AGTIRENLRLGRPDA---SDEEL-EAALEAA---GLDEfVAAlpdgldTPLGEGgrglSGGQAQ 480
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIV 224
Cdd:COG4988 481 RLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVIL-ITHRLALLAQADRILVLDDGRIV 550
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
4-232 |
2.30e-32 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 119.14 E-value: 2.30e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTNYH----VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEE 79
Cdd:TIGR02769 2 LLEVRDVTHTYRTGGLFGAKqrapVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 ALAKLRlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNK--RALELMENMGI-SDIASHYITEASGGQLQRVS 156
Cdd:TIGR02769 82 QRRAFR-RDVQLVFQDSPSAVNPRMTVRQIIGEPLRHLTSLDESEQkaRIAELLDMVGLrSEDADKLPRQLSGGQLQRIN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNIN-RGGTTIMLVTHDVKVAAK-TERILFMADGEIVSEIQLGKL 232
Cdd:TIGR02769 161 IARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQqAFGTAYLFITHDLRLVQSfCQRVAVMDKGQIVEECDVAQL 238
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
4-224 |
2.79e-32 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 118.26 E-value: 2.79e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVnkTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISG-MDQMSSGSVKIDSKELScmkEEALA 82
Cdd:COG1119 3 LLELRNV--TVRRGGKT---ILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGdLPPTYGNDVRLFGERRG---GEDVW 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KLRlTEIGFI--FQQSNLLRNLNLFDnIILSAYLA------KCESKKIvnKRALELMENMGISDIASHYITEASGGQLQR 154
Cdd:COG1119 75 ELR-KRIGLVspALQLRFPRDETVLD-VVLSGFFDsiglyrEPTDEQR--ERARELLELLGLAHLADRPFGTLSQGEQRR 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 155 VSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:COG1119 151 VLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAeGAPTLVLVTHHVEeIPPGITHVLLLKDGRVV 222
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
24-229 |
6.16e-32 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 117.49 E-value: 6.16e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAlaklrlteiGFIFQQSNLLRNLN 103
Cdd:PRK11248 16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER---------GVVFQNEGLLPWRN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCeSKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTE 183
Cdd:PRK11248 87 VQDNVAFGLQLAGV-EKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTRE 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446644341 184 EVMQILLNI-NRGGTTIMLVTHDVKVAA--KTERILFMAD-GEIVSEIQL 229
Cdd:PRK11248 166 QMQTLLLKLwQETGKQVLLITHDIEEAVfmATELVLLSPGpGRVVERLPL 215
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
27-225 |
7.41e-32 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 116.24 E-value: 7.41e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 27 NIDLEIyEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKEL--SCMKEEALAKLRltEIGFIFQQSNLLRNLNL 104
Cdd:cd03297 16 KIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLfdSRKKINLPPQQR--KIGLVFQQYALFPHLNV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 105 FDNIilsAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEE 184
Cdd:cd03297 93 RENL---AFGLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQ 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446644341 185 VMQIL------LNInrggtTIMLVTHDVKVAAK-TERILFMADGEIVS 225
Cdd:cd03297 170 LLPELkqikknLNI-----PVIFVTHDLSEAEYlADRIVVMEDGRLQY 212
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
5-232 |
1.57e-31 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 116.01 E-value: 1.57e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdgntnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkEEALAKl 84
Cdd:COG3840 2 LRLDDLTYRY-------GDFPLRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLT---ALPPAE- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIgfIFQQSNLLRNLNLFDNIIL----SAYLAKCESKKIVnkralELMENMGISDIASHYITEASGGQLQRVSICRA 160
Cdd:COG3840 71 RPVSM--LFQENNLFPHLTVAQNIGLglrpGLKLTAEQRAQVE-----QALERVGLAGLLDRLPGQLSGGQRQRVALARC 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 161 LINNPNIIFADEPTGAL--NLKstEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIVSEIQLGKL 232
Cdd:COG3840 144 LVRKRPILLLDEPFSALdpALR--QEMLDLVDELCRErGLTVLMVTHDPEDAARiADRVLLVADGRIAADGPTAAL 217
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
40-224 |
1.78e-31 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 117.98 E-value: 1.78e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 40 VMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkeEALAKLRltEIGFIFQQSNLLRNLNLFDNIILSAYLAKcES 119
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVT----NVPPHLR--HINMVFQSYALFPHMTVEENVAFGLKMRK-VP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 120 KKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTT 198
Cdd:TIGR01187 74 RAEIKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQlGIT 153
|
170 180
....*....|....*....|....*..
gi 446644341 199 IMLVTHDVKVA-AKTERILFMADGEIV 224
Cdd:TIGR01187 154 FVFVTHDQEEAmTMSDRIAIMRKGKIA 180
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
4-226 |
5.36e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 115.56 E-value: 5.36e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmDGntnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScMKEEALAK 83
Cdd:PRK13639 1 ILETRDLKYSYP-DG---TEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIK-YDKKSLLE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRLTeIGFIFQQSnllrNLNLFDNII--------LSAYLAKCESKKIVnKRALELMENMGISDIASHYIteaSGGQLQRV 155
Cdd:PRK13639 76 VRKT-VGIVFQNP----DDQLFAPTVeedvafgpLNLGLSKEEVEKRV-KEALKAVGMEGFENKPPHHL---SGGQKKRV 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 156 SICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK13639 147 AIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVyADKVYVMSDGKIIKE 218
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
5-226 |
7.44e-31 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 115.07 E-value: 7.44e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKE------ 78
Cdd:PRK10619 6 LNVIDLHKRYG-----EHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDkdgqlk 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 79 ----EALAKLRlTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIA-SHYITEASGGQLQ 153
Cdd:PRK10619 81 vadkNQLRLLR-TRLTMVFQHFNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAqGKYPVHLSGGQQQ 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK10619 160 RVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHvSSHVIFLHQGKIEEE 233
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
8-231 |
8.59e-31 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 117.05 E-value: 8.59e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 8 KQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKElscMKEEALAKlrlT 87
Cdd:PRK11000 7 RNVTKAY---GDV--VISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKR---MNDVPPAE---R 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 88 EIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNI 167
Cdd:PRK11000 76 GVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEI-NQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSV 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 168 IFADEPTGalNLKSTEEVmQILLNIN----RGGTTIMLVTHDvKVAAKT--ERILFMADGEIVseiQLGK 231
Cdd:PRK11000 155 FLLDEPLS--NLDAALRV-QMRIEISrlhkRLGRTMIYVTHD-QVEAMTlaDKIVVLDAGRVA---QVGK 217
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
5-223 |
4.35e-30 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 110.38 E-value: 4.35e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVnkTYSMDGNTNYhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:cd03246 1 LEVENV--SFRYPGAEPP-VLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNLLRNlNLFDNIIlsaylakceskkivnkralelmenmgisdiashyiteaSGGQLQRVSICRALINN 164
Cdd:cd03246 78 ----VGYLPQDDELFSG-SIAENIL--------------------------------------SGGQRQRLGLARALYGN 114
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEI 223
Cdd:cd03246 115 PRILVLDEPNSHLDVEGERALNQAIAALKAAGATRIVIAHRPETLASADRILVLEDGRV 173
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
5-224 |
5.14e-30 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 111.53 E-value: 5.14e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKeeaLAKL 84
Cdd:cd03245 3 IEFRNVSFSYP---NQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLD---PADL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNLLrNLNLFDNIILSAYLAKCEskkivnkRALELMENMGISD-IASH------YITEA----SGGQLQ 153
Cdd:cd03245 77 R-RNIGYVPQDVTLF-YGTLRDNITLGAPLADDE-------RILRAAELAGVTDfVNKHpngldlQIGERgrglSGGQRQ 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNInRGGTTIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:cd03245 148 AVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQL-LGDKTLIIITHRPSLLDLVDRIIVMDSGRIV 217
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
4-236 |
5.65e-30 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 112.00 E-value: 5.65e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:COG0410 3 MLEVENLHAGY---GGI--HVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIAR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlteIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKivnKRALELM-----------ENMGisdiashyiTEASGGQL 152
Cdd:COG0410 78 LG---IGYVPEGRRIFPSLTVEENLLLGAYARRDRAEV---RADLERVyelfprlkerrRQRA---------GTLSGGEQ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 153 QRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSEIQLGK 231
Cdd:COG0410 143 QMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNREGVTILLVEQNARFALEiADRAYVLERGRIVLEGTAAE 222
|
....*
gi 446644341 232 LRNDD 236
Cdd:COG0410 223 LLADP 227
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-226 |
1.13e-29 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 112.42 E-value: 1.13e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkEEA 80
Cdd:PRK13635 2 KEEIIRVEHISFRYP---DAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLS---EET 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLRlTEIGFIFQQSNllrnlNLF------DNIILSAYLAKCESKKIVnKRALELMENMGISDIASHYITEASGGQLQR 154
Cdd:PRK13635 76 VWDVR-RQVGMVFQNPD-----NQFvgatvqDDVAFGLENIGVPREEMV-ERVDQALRQVGMEDFLNREPHRLSGGQKQR 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 155 VSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:PRK13635 149 VAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEqKGITVLSITHDLDEAAQADRVIVMNKGEILEE 221
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-224 |
1.45e-29 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 115.94 E-value: 1.45e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSMDGNTNyHVLKNIDLEIYEGEFVSVMGPSGSGKS-T------LL-YNISgmdqMSSGSVKIDSKE 72
Cdd:COG4172 3 SMPLLSVEDLSVAFGQGGGTV-EAVKGVSFDIAAGETLALVGESGSGKSvTalsilrLLpDPAA----HPSGSILFDGQD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 73 LSCMKEEALAKLRLTEIGFIFQQ---SnllrnLN-LF---DNIILSAYLAKCESKKIVNKRALELMENMGISDIASH--- 142
Cdd:COG4172 78 LLGLSERELRRIRGNRIAMIFQEpmtS-----LNpLHtigKQIAEVLRLHRGLSGAAARARALELLERVGIPDPERRlda 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 143 YITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAK-TERILFMAD 220
Cdd:COG4172 153 YPHQLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQReLGMALLLITHDLGVVRRfADRVAVMRQ 232
|
....
gi 446644341 221 GEIV 224
Cdd:COG4172 233 GEIV 236
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
8-247 |
1.97e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 111.80 E-value: 1.97e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 8 KQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKEL-SCMKEEALAKLRl 86
Cdd:PRK13646 6 DNVSYTYQKGTPYEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITItHKTKDKYIRPVR- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 87 TEIGFIFQ--QSNLLRNlNLFDNIILSAYLAKCESKKiVNKRALELMENMGIS-DIASHYITEASGGQLQRVSICRALIN 163
Cdd:PRK13646 85 KRIGMVFQfpESQLFED-TVEREIIFGPKNFKMNLDE-VKNYAHRLLMDLGFSrDVMSQSPFQMSGGQMRKIAIVSILAM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNIN-RGGTTIMLVTHDV-KVAAKTERILFMADGEIVSEIQLGKLRNDDlkare 241
Cdd:PRK13646 163 NPDIIVLDEPTAGLDPQSKRQVMRLLKSLQtDENKTIILVSHDMnEVARYADEVIVMKEGSIVSQTSPKELFKDK----- 237
|
....*.
gi 446644341 242 EKLLNW 247
Cdd:PRK13646 238 KKLADW 243
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
5-224 |
2.60e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 111.46 E-value: 2.60e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSC-MKEEALAK 83
Cdd:PRK13641 3 IKFENVDYIYSPGTPMEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPeTGNKNLKK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlTEIGFIFQ--QSNLLRNLNLFDniILSAYLAKCESKKIVNKRALELMENMGIS-DIASHYITEASGGQLQRVSICRA 160
Cdd:PRK13641 83 LR-KKVSLVFQfpEAQLFENTVLKD--VEFGPKNFGFSEDEAKEKALKWLKKVGLSeDLISKSPFELSGGQMRRVAIAGV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 161 LINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIV 224
Cdd:PRK13641 160 MAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMdDVAEYADDVLVLEHGKLI 224
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
11-224 |
2.79e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 111.24 E-value: 2.79e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 11 NKTYSMDGNTNYhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkEEALAKLRlTEIG 90
Cdd:PRK13632 12 NVSFSYPNSENN-ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITIS---KENLKEIR-KKIG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 91 FIFQQSNllrnlNLFDNIILSAYLA-----KCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNP 165
Cdd:PRK13632 87 IIFQNPD-----NQFIGATVEDDIAfglenKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNP 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 166 NIIFADEPTGALNLKSTEEVMQILLNINRGGT-TIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:PRK13632 162 EIIIFDESTSMLDPKGKREIKKIMVDLRKTRKkTLISITHDMDEAILADKVIVFSEGKLI 221
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
5-224 |
3.08e-29 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 109.20 E-value: 3.08e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVsVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKl 84
Cdd:cd03264 1 LQLENLTKRYG-----KKRALDGVSLTLGPGMYG-LLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRR- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKiVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03264 74 ----IGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKE-VKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGD 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQIL--LNINRggtTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:cd03264 149 PSILIVDEPTAGLDPEERIRFRNLLseLGEDR---IVILSTHIVEdVESLCNQVAVLNKGKLV 208
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
5-226 |
5.88e-29 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 107.78 E-value: 5.88e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMkEEALAKL 84
Cdd:cd03247 1 LSINNVSFSY---PEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDL-EKALSSL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQsnllrnLNLFDNIIlsaylakceskkivnkralelMENMGisdiashyiTEASGGQLQRVSICRALINN 164
Cdd:cd03247 77 ----ISVLNQR------PYLFDTTL---------------------RNNLG---------RRFSGGERQRLALARILLQD 116
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:cd03247 117 APIVLLDEPTVGLDPITERQLLSLIFEVLKDKTLIW-ITHHLTGIEHMDKILFLENGKIIMQ 177
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
24-224 |
8.19e-29 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 108.51 E-value: 8.19e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQ---MSSGSVKIDSKELScmkeealAKLRLTEIGFIFQQSNLLR 100
Cdd:cd03234 22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEgggTTSGQILFNGQPRK-------PDQFQKCVAYVRQDDILLP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 NLNLFDNIILSAYLA--KCESKKIVNKR-ALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGAL 177
Cdd:cd03234 95 GLTVRETLTYTAILRlpRKSSDAIRKKRvEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGL 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446644341 178 NLKSTEEVMQILLNINRGGTTIMLVTHDVK--VAAKTERILFMADGEIV 224
Cdd:cd03234 175 DSFTALNLVSTLSQLARRNRIVILTIHQPRsdLFRLFDRILLLSSGEIV 223
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
5-233 |
8.91e-29 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 108.61 E-value: 8.91e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKl 84
Cdd:cd03265 1 IEVENLVKKY--GDFE---AVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREVRRR- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03265 75 ----IGIVFQDLSVDDELTGWENLYIHARLYGVPGAER-RERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHR 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAK-TERILFMADGEIVSEIQLGKLR 233
Cdd:cd03265 150 PEVLFLDEPTIGLDPQTRAHVWEYIEKLKEeFGMTILLTTHYMEEAEQlCDRVAIIDHGRIIAEGTPEELK 220
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
5-226 |
1.66e-28 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 108.01 E-value: 1.66e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSC--MKEEAla 82
Cdd:cd03218 1 LRAENLSKRYG-----KRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKlpMHKRA-- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 klRLTeIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALI 162
Cdd:cd03218 74 --RLG-IGYLPQEASIFRKLTVEENILAVLEIRG-LSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALA 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 163 NNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIVSE 226
Cdd:cd03218 150 TNPKFLLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVReTLSITDRAYIIYEGKVLAE 214
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
1-237 |
2.07e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 108.67 E-value: 2.07e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmDGNtnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEA 80
Cdd:PRK13647 1 MDNIIEVEDLHFRYK-DGT---KALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKW 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKlrltEIGFIFQQ-SNLLRNLNLFDNII---LSAYLAKCESKKIVNKrALELMENMGISDIASHYIteaSGGQLQRVS 156
Cdd:PRK13647 77 VRS----KVGLVFQDpDDQVFSSTVWDDVAfgpVNMGLDKDEVERRVEE-ALKAVRMWDFRDKPPYHL---SYGQKKRVA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSEIQLGKLRND 235
Cdd:PRK13647 149 IAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEwADQVIVLKEGRVLAEGDKSLLTDE 228
|
..
gi 446644341 236 DL 237
Cdd:PRK13647 229 DI 230
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
24-209 |
2.64e-28 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 106.35 E-value: 2.64e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEeALAKLRlTEIGFIFQQ-------- 95
Cdd:TIGR01166 7 VLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLDYSRK-GLLERR-QRVGLVFQDpddqlfaa 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 96 ------SNLLRNLNLfdniilsaylakceSKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIF 169
Cdd:TIGR01166 85 dvdqdvAFGPLNLGL--------------SEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLL 150
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446644341 170 ADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVA 209
Cdd:TIGR01166 151 LDEPTAGLDPAGREQMLAILRRLRAEGMTVVISTHDVDLA 190
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-224 |
3.33e-28 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 107.82 E-value: 3.33e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQM-----SSGSVKIDSKELSC 75
Cdd:COG1117 8 LEPKIEVRNLNVYYG-----DKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLipgarVEGEILLDGEDIYD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 76 MKEEaLAKLRlTEIGFIFQQSNLLrNLNLFDNIILSAYLAKCESKK----IV-----------------NKRALELmenm 134
Cdd:COG1117 83 PDVD-VVELR-RRVGMVFQKPNPF-PKSIYDNVAYGLRLHGIKSKSeldeIVeeslrkaalwdevkdrlKKSALGL---- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 135 gisdiashyiteaSGGQLQRVSICRALINNPNIIFADEPTGALNLKST---EEVMQILlninRGGTTIMLVTHDVKVAAk 211
Cdd:COG1117 156 -------------SGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTakiEELILEL----KKDYTIVIVTHNMQQAA- 217
|
250
....*....|....*..
gi 446644341 212 teRI----LFMADGEIV 224
Cdd:COG1117 218 --RVsdytAFFYLGELV 232
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
5-245 |
3.60e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 109.02 E-value: 3.60e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKI-----DSKELSCMKEE 79
Cdd:PRK13651 3 IKVKNIVKIFNKKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWifkdeKNKKKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 ALAKLRLT---------------EIGFIFQqsnlLRNLNLFDNII--------LSAYLAKCESKKivnkRALELMENMGI 136
Cdd:PRK13651 83 VLEKLVIQktrfkkikkikeirrRVGVVFQ----FAEYQLFEQTIekdiifgpVSMGVSKEEAKK----RAAKYIELVGL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 137 SDiasHYIT----EASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAK 211
Cdd:PRK13651 155 DE---SYLQrspfELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLdNVLEW 231
|
250 260 270
....*....|....*....|....*....|....
gi 446644341 212 TERILFMADGEIVSEIQLGKLRNDDLKAREEKLL 245
Cdd:PRK13651 232 TKRTIFFKDGKIIKDGDTYDILSDNKFLIENNME 265
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-246 |
5.44e-28 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 107.48 E-value: 5.44e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:COG1101 1 MLELKNLSKTFNPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LrlteIGFIFQqsNLLR----NLNLFDNIILsAY-------LAKCESKKivnKRAL--ELME--NMGISDIASHYITEAS 148
Cdd:COG1101 81 Y----IGRVFQ--DPMMgtapSMTIEENLAL-AYrrgkrrgLRRGLTKK---RRELfrELLAtlGLGLENRLDTKVGLLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 149 GGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAKT-ERILFMADGEIVSE 226
Cdd:COG1101 151 GGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIvEENNLTTLMVTHNMEQALDYgNRLIMMHEGRIILD 230
|
250 260
....*....|....*....|....*...
gi 446644341 227 I---QLGKLRNDDL-----KAREEKLLN 246
Cdd:COG1101 231 VsgeEKKKLTVEDLlelfeEIRGEELAD 258
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
5-224 |
6.92e-28 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 107.12 E-value: 6.92e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVnkTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:COG4559 2 LEAENL--SVRLGGRT---LLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 R--LTeigfifQQSNLLRNLNLFDNIILSAYlAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALI 162
Cdd:COG4559 77 RavLP------QHSSLAFPFTVEEVVALGRA-PHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLA 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 163 -------NNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:COG4559 150 qlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLNLAAQyADRILLLHQGRLV 219
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
9-224 |
8.99e-28 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 105.65 E-value: 8.99e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 9 QVNKTYSMDGNTNYHvlknIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAlaklrlTE 88
Cdd:cd03298 2 RLDKIRFSYGEQPMH----FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPAD------RP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 89 IGFIFQQSNLLRNLNLFDNIIL----SAYLAKCESKKIvnKRALelmENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03298 72 VSMLFQENNLFAHLTVEQNVGLglspGLKLTAEDRQAI--EVAL---ARVGLAGLEKRLPGELSGGERQRVALARVLVRD 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:cd03298 147 KPVLLLDEPFAALDPALRAEMLDLVLDLHAeTKMTVLMVTHQPEDAKRlAQRVVFLDNGRIA 208
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
4-231 |
9.66e-28 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 109.15 E-value: 9.66e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKqvNKTYSMDGNtnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEealak 83
Cdd:PRK11607 19 LLEIR--NLTKSFDGQ---HAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPP----- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 lRLTEIGFIFQQSNLLRNLNLFDNIILSA---YLAKCEskkiVNKRALELMENMGISDIASHYITEASGGQLQRVSICRA 160
Cdd:PRK11607 89 -YQRPINMMFQSYALFPHMTVEQNIAFGLkqdKLPKAE----IASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARS 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 161 LINNPNIIFADEPTGALNLKSTE----EVMQILlniNRGGTTIMLVTHDVKVAAKTE-RILFMADGEIVseiQLGK 231
Cdd:PRK11607 164 LAKRPKLLLLDEPMGALDKKLRDrmqlEVVDIL---ERVGVTCVMVTHDQEEAMTMAgRIAIMNRGKFV---QIGE 233
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-224 |
1.28e-27 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 106.40 E-value: 1.28e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMS-----SGSVKIDSKELSC 75
Cdd:PRK14239 2 TEPILQVSDLSVYYN-----KKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNpevtiTGSIVYNGHNIYS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 76 MKEEALaKLRlTEIGFIFQQSNLLrNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEA----SGGQ 151
Cdd:PRK14239 77 PRTDTV-DLR-KEIGMVFQQPNPF-PMSIYENVVYGLRLKGIKDKQVLDEAVEKSLKGASIWDEVKDRLHDSalglSGGQ 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 152 LQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNInRGGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK14239 154 QQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGL-KDDYTMLLVTRSMQQASRiSDRTGFFLDGDLI 226
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
24-224 |
1.33e-27 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 105.65 E-value: 1.33e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrltEIGFIFQqSNLLRNLN 103
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRR----QVGVVLQ-ENVLFNRS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVNKRA------LELMEnmGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGAL 177
Cdd:cd03252 92 IRDNIALADPGMSMERVIEAAKLAgahdfiSELPE--GYDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATSAL 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446644341 178 NLKSTEEVMQILLNINRGGTTImLVTHDVKVAAKTERILFMADGEIV 224
Cdd:cd03252 170 DYESEHAIMRNMHDICAGRTVI-IIAHRLSTVKNADRIIVMEKGRIV 215
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
5-224 |
1.46e-27 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 110.24 E-value: 1.46e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:COG4987 334 LELEDVSFRYPGAGRP---VLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRR 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNL----LRNlNLfdniilsaylakceskKIVNKRA-----LELMENMGISDIASHY-------ITEA- 147
Cdd:COG4987 411 ----IAVVPQRPHLfdttLRE-NL----------------RLARPDAtdeelWAALERVGLGDWLAALpdgldtwLGEGg 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 148 ---SGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIV 224
Cdd:COG4987 470 rrlSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLL-ITHRLAGLERMDRILVLEDGRIV 548
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
5-224 |
2.43e-27 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 105.01 E-value: 2.43e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscmKEEALAKL 84
Cdd:cd03251 1 VEFKNVTFRYPGDGPP---VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDV---RDYTLASL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIfQQSNLLRNLNLFDNIilsAYLAKCESKKIVNK-----RALELMENM--GISDIASHYITEASGGQLQRVSI 157
Cdd:cd03251 75 R-RQIGLV-SQDVFLFNDTVAENI---AYGRPGATREEVEEaaraaNAHEFIMELpeGYDTVIGERGVKLSGGQRQRIAI 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 158 CRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTImLVTHDVKVAAKTERILFMADGEIV 224
Cdd:cd03251 150 ARALLKDPPILILDEATSALDTESERLVQAALERLMKNRTTF-VIAHRLSTIENADRIVVLEDGKIV 215
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
24-225 |
3.07e-27 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 104.98 E-value: 3.07e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrlTEIGFIFQQSNLLRNLN 103
Cdd:PRK10895 18 VVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARAR---RGIGYLPQEASIFRRLS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTE 183
Cdd:PRK10895 95 VYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVI 174
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446644341 184 EVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIVS 225
Cdd:PRK10895 175 DIKRIIEHLRDSGLGVLITDHNVReTLAVCERAYIVSQGHLIA 217
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
11-224 |
3.23e-27 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 103.40 E-value: 3.23e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 11 NKTYSMDGNTNYH---VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISG--MDQMSSGSVKIDSKELScmkEEALAKLr 85
Cdd:cd03213 8 NLTVTVKSSPSKSgkqLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLD---KRSFRKI- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 86 lteIGFIFQQSNLLRNLNLFDNIILSAYLakceskkivnkRALelmenmgisdiashyiteaSGGQLQRVSICRALINNP 165
Cdd:cd03213 84 ---IGYVPQDDILHPTLTVRETLMFAAKL-----------RGL-------------------SGGERKRVSIALELVSNP 130
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 166 NIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV--KVAAKTERILFMADGEIV 224
Cdd:cd03213 131 SLLFLDEPTSGLDSSSALQVMSLLRRLADTGRTIICSIHQPssEIFELFDKLLLLSQGRVI 191
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
6-224 |
3.63e-27 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 104.78 E-value: 3.63e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 6 EVKQVNKTYsmdGNTNyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlR 85
Cdd:COG4604 3 EIKNVSKRY---GGKV--VLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAK-R 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 86 LTeigfIFQQSNLL------RNLNLFDNI-----ILSAylakcESKKIVNkRALELMEnmgISDIASHYITEASGGQLQR 154
Cdd:COG4604 77 LA----ILRQENHInsrltvRELVAFGRFpyskgRLTA-----EDREIID-EAIAYLD---LEDLADRYLDELSGGQRQR 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 155 VSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:COG4604 144 AFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADElGKTVVIVLHDINFASCyADHIVAMKDGRVV 215
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
6-226 |
3.92e-27 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 104.23 E-value: 3.92e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 6 EVKQVNKTYsmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLr 85
Cdd:cd03254 4 EFENVNFSY----DEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSM- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 86 lteIGFIFQQSNLLRNlNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEA----SGGQLQRVSICRAL 161
Cdd:cd03254 79 ---IGVVLQDTFLFSG-TIMENIRLGRPNATDEEVIEAAKEAGAHDFIMKLPNGYDTVLGENggnlSQGERQLLAIARAM 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:cd03254 155 LRDPKILILDEATSNIDTETEKLIQEALEKLMKGRTSII-IAHRLSTIKNADKILVLDDGKIIEE 218
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-221 |
4.92e-27 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 104.05 E-value: 4.92e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSMD--GNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKE-----L 73
Cdd:COG4778 1 MTTLLEVENLSKTFTLHlqGGKRLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGgwvdlA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 74 SCMKEEALAkLRLTEIGFIFQqsnllrnlnlFDNII--LSAY-------LAKCESKKIVNKRALELMENMGI-SDIASHY 143
Cdd:COG4778 81 QASPREILA-LRRRTIGYVSQ----------FLRVIprVSALdvvaeplLERGVDREEARARARELLARLNLpERLWDLP 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 144 ITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKV-AAKTERILFMADG 221
Cdd:COG4778 150 PATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEEVrEAVADRVVDVTPF 228
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
2-224 |
8.23e-27 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 105.96 E-value: 8.23e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNKTYSmdGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkEEAL 81
Cdd:PRK11432 4 KNFVVLKNITKRFG--SNT---VIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVT---HRSI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKlrlTEIGFIFQQSNLLRNLNLFDNIilsAY------LAKCESKKIVnKRALELMENMGISDiasHYITEASGGQLQRV 155
Cdd:PRK11432 76 QQ---RDICMVFQSYALFPHMSLGENV---GYglkmlgVPKEERKQRV-KEALELVDLAGFED---RYVDQISGGQQQRV 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 156 SICRALINNPNIIFADEPTGAL--NLKST--EEV--MQILLNInrggtTIMLVTHDVKVA-AKTERILFMADGEIV 224
Cdd:PRK11432 146 ALARALILKPKVLLFDEPLSNLdaNLRRSmrEKIreLQQQFNI-----TSLYVTHDQSEAfAVSDTVIVMNKGKIM 216
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
4-225 |
8.33e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 104.82 E-value: 8.33e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKI-DSKELSCMKEEALA 82
Cdd:PRK13643 1 MIKFEKVNYTYQPNSPFASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVgDIVVSSTSKQKEIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KLRlTEIGFIFQqsnlLRNLNLFDNIILSAY--------LAKCESKKIvnkrALELMENMGIS-DIASHYITEASGGQLQ 153
Cdd:PRK13643 81 PVR-KKVGVVFQ----FPESQLFEETVLKDVafgpqnfgIPKEKAEKI----AAEKLEMVGLAdEFWEKSPFELSGGQMR 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVS 225
Cdd:PRK13643 152 RVAIAGILAMEPEVLVLDEPTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMdDVADYADYVYLLEKGHIIS 224
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
4-237 |
8.86e-27 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 107.80 E-value: 8.86e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdGNtnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMK-EEALA 82
Cdd:COG1129 4 LLEMRGISKSFG--GV---KALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSpRDAQA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KlrltEIGFIFQQSNLLRNLNLFDNIILSAYLAKcesKKIVNKRAL-----ELMENMGIS----DIASHYiteaSGGQLQ 153
Cdd:COG1129 79 A----GIAIIHQELNLVPNLSVAENIFLGREPRR---GGLIDWRAMrrrarELLARLGLDidpdTPVGDL----SVAQQQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIVSEIQLGKL 232
Cdd:COG1129 148 LVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQGVAIIYISHRLDeVFEIADRVTVLRDGRLVGTGPVAEL 227
|
....*
gi 446644341 233 RNDDL 237
Cdd:COG1129 228 TEDEL 232
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
4-230 |
2.06e-26 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 103.23 E-value: 2.06e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTNYH----VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEE 79
Cdd:PRK10419 3 LLNVSGLSHHYAHGGLSGKHqhqtVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 ALAKLRLTeIGFIFQQS---------------NLLRNLNLFDniilsaylakcESKKIVnkRALELMENMGISD-IASHY 143
Cdd:PRK10419 83 QRKAFRRD-IQMVFQDSisavnprktvreiirEPLRHLLSLD-----------KAERLA--RASEMLRAVDLDDsVLDKR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 144 ITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAK-TERILFMADG 221
Cdd:PRK10419 149 PPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLqQQFGTACLFITHDLRLVERfCQRVMVMDNG 228
|
....*....
gi 446644341 222 EIVSEIQLG 230
Cdd:PRK10419 229 QIVETQPVG 237
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
8-224 |
3.08e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 103.56 E-value: 3.08e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 8 KQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSC-MKEEALAKLRl 86
Cdd:PRK13634 6 QKVEHRYQYKTPFERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAgKKNKKLKPLR- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 87 TEIGFIFQ--QSNLLRNLNLFD------NIILSAYLAKceskkivnKRALELMENMGIS-DIASHYITEASGGQLQRVSI 157
Cdd:PRK13634 85 KKVGIVFQfpEHQLFEETVEKDicfgpmNFGVSEEDAK--------QKAREMIELVGLPeELLARSPFELSGGQMRRVAI 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 158 CRALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:PRK13634 157 AGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKeKGLTTVLVTHSMEdAARYADQIVVMHKGTVF 225
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
24-224 |
4.00e-26 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 102.03 E-value: 4.00e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrlteIGFIF-QQSNLLRNL 102
Cdd:cd03267 36 ALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKFLRR-----IGVVFgQKTQLWWDL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 103 NLFDNIILSAYLAKCESKKIVNKRAlELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKST 182
Cdd:cd03267 111 PVIDSFYLLAAIYDLPPARFKKRLD-ELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQ 189
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446644341 183 EEVMQILLNINRG-GTTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:cd03267 190 ENIRNFLKEYNRErGTTVLLTSHYMKdIEALARRVLVIDKGRLL 233
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
5-226 |
4.40e-26 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 102.16 E-value: 4.40e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVnkTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:PRK13548 3 LEARNL--SVRLGGRT---LLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlteiGFIFQQSNL----------------LRNLNLFDNIILSAYLAKCeskkivnkralelmenmGISDIASHYITEAS 148
Cdd:PRK13548 78 R----AVLPQHSSLsfpftveevvamgrapHGLSRAEDDALVAAALAQV-----------------DLAHLAGRDYPQLS 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 149 GGQLQRVSICRALI------NNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAK-TERILFMAD 220
Cdd:PRK13548 137 GGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLaHERGLAVIVVLHDLNLAARyADRIVLLHQ 216
|
....*.
gi 446644341 221 GEIVSE 226
Cdd:PRK13548 217 GRLVAD 222
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
2-224 |
6.02e-26 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 103.63 E-value: 6.02e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNKTYSMDGNTNY-----HVLKNID---LEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKEL 73
Cdd:PRK15079 6 KVLLEVADLKVHFDIKDGKQWfwqppKTLKAVDgvtLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 74 SCMKEEALAKLRlTEIGFIFQQSnlLRNLN---LFDNII---LSAYLAKCeSKKIVNKRALELMENMGI-SDIASHYITE 146
Cdd:PRK15079 86 LGMKDDEWRAVR-SDIQMIFQDP--LASLNprmTIGEIIaepLRTYHPKL-SRQEVKDRVKAMMLKVGLlPNLINRYPHE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 147 ASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK15079 162 FSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREmGLSLIFIAHDLAVVKHiSDRVLVMYLGHAV 241
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-226 |
6.69e-26 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 102.47 E-value: 6.69e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSMDGNTNYH-VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSkeLSCMKEE 79
Cdd:PRK13633 1 MNEMIKCKNVSYKYESNEESTEKlALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDG--LDTSDEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 ALAKLRlTEIGFIFQQSnllrnlnlfDNIILSAYLAK----------CESKKIvNKRALELMENMGISDIASHYITEASG 149
Cdd:PRK13633 79 NLWDIR-NKAGMVFQNP---------DNQIVATIVEEdvafgpenlgIPPEEI-RERVDESLKKVGMYEYRRHAPHLLSG 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 150 GQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:PRK13633 148 GQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKyGITIILITHYMEEAVEADRIIVMDSGKVVME 225
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
21-226 |
7.76e-26 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 101.53 E-value: 7.76e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 21 NYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMS-----SGSVKIDSKELSCMKeeaLAKLRlTEIGFIFQQ 95
Cdd:PRK14247 15 QVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELYpearvSGEVYLDGQDIFKMD---VIELR-RRVQMVFQI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 96 SNLLRNLNLFDNIILSAYLAK-CESKKIVNKRALELMENMGISDIASHYIT----EASGGQLQRVSICRALINNPNIIFA 170
Cdd:PRK14247 91 PNPIPNLSIFENVALGLKLNRlVKSKKELQERVRWALEKAQLWDEVKDRLDapagKLSGGQQQRLCIARALAFQPEVLLA 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 171 DEPTGALNLKSTEEVMQILLNINRgGTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK14247 171 DEPTANLDPENTAKIESLFLELKK-DMTIVLVTHFPQQAARiSDYVAFLYKGQIVEW 226
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
5-227 |
8.01e-26 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 100.37 E-value: 8.01e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEalakl 84
Cdd:cd03268 1 LKTNDLTKTYG-----KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEA----- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rLTEIGFIFQQSNLLRNLNLFDNIILSAYLakcesKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:cd03268 71 -LRRIGALIEAPGFYPNLTARENLRLLARL-----LGIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGN 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGEIVSEI 227
Cdd:cd03268 145 PDLLILDEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVaDRIGIINKGKLIEEG 208
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
5-224 |
1.14e-25 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 100.05 E-value: 1.14e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAlakl 84
Cdd:cd03269 1 LEVENVTKRFG-----RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNR---- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNLLRNLNLFDNIIlsaYLA--KCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALI 162
Cdd:cd03269 72 ----IGYLPEERGLYPKMKVIDQLV---YLAqlKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVI 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 163 NNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIV 224
Cdd:cd03269 145 HDPELLILDEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMeLVEELCDRVLLLNKGRAV 207
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
4-226 |
1.17e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 101.85 E-value: 1.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmDGNtnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScMKEEALAK 83
Cdd:PRK13636 5 ILKVEELNYNYS-DGT---HALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPID-YSRKGLMK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlTEIGFIFQQ-SNLLRNLNLFDNIILSAYLAKCESKKiVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALI 162
Cdd:PRK13636 80 LR-ESVGMVFQDpDNQLFSASVYQDVSFGAVNLKLPEDE-VRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLV 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 163 NNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVK-VAAKTERILFMADGEIVSE 226
Cdd:PRK13636 158 MEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDiVPLYCDNVFVMKEGRVILQ 223
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
5-224 |
1.52e-25 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 104.95 E-value: 1.52e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNtnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKElscMKEEALAKL 84
Cdd:TIGR03375 464 IEFRNVSFAYPGQET---PALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVD---IRQIDPADL 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIfQQSNLLRNLNLFDNIILSAYLAkcESKKIVnkRALELMenmGISDIASHY-------ITEA----SGGQLQ 153
Cdd:TIGR03375 538 R-RNIGYV-PQDPRLFYGTLRDNIALGAPYA--DDEEIL--RAAELA---GVTEFVRRHpdgldmqIGERgrslSGGQRQ 608
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNInRGGTTIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:TIGR03375 609 AVALARALLRDPPILLLDEPTSAMDNRSEERFKDRLKRW-LAGKTLVLVTHRTSLLDLVDRIIVMDNGRIV 678
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
4-226 |
1.80e-25 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 99.75 E-value: 1.80e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmKEEALAK 83
Cdd:cd03266 1 MITADALTKRFR-DVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVV--KEPAEAR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlteIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVSICRALIN 163
Cdd:cd03266 78 RR---LGFVSDSTGLYDRLTARENLEYFAGLYGLKGDEL-TARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVH 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVSE 226
Cdd:cd03266 154 DPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMqEVERLCDRVVVLHRGRVVYE 217
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-225 |
2.04e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 100.96 E-value: 2.04e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVnkTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkEEA 80
Cdd:PRK13650 1 MSNIIEVKNL--TFKYKEDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLT---EEN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLRlTEIGFIFQQSnllrnlnlfDNIILSAYLAK-----CESKKI----VNKRALELMENMGISDIASHYITEASGGQ 151
Cdd:PRK13650 76 VWDIR-HKIGMVFQNP---------DNQFVGATVEDdvafgLENKGIpheeMKERVNEALELVGMQDFKEREPARLSGGQ 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 152 LQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAKTERILFMADGEIVS 225
Cdd:PRK13650 146 KQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIrDDYQMTVISITHDLDEVALSDRVLVMKNGQVES 220
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
24-216 |
3.75e-25 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 98.07 E-value: 3.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKE---LSCMKEEALAKLRLT-----EIGFiFQQ 95
Cdd:NF040873 7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGArvaYVPQRSEVPDSLPLTvrdlvAMGR-WAR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 96 SNLLRNLNLFDNIILSaylakceskkivnkralELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTG 175
Cdd:NF040873 86 RGLWRRLTRDDRAAVD-----------------DALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTT 148
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446644341 176 ALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERIL 216
Cdd:NF040873 149 GLDAESRERIIALLAEEHARGATVVVVTHDLELVRRADPCV 189
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
24-224 |
3.91e-25 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 103.32 E-value: 3.91e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLrlteIGFIFQQSNLLrNLN 103
Cdd:COG1132 355 VLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQ----IGVVPQDTFLF-SGT 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIIL---SAYLAKCEskkivnkRALELmenMGISD-IAS------HYITEA----SGGQLQRVSICRALINNPNIIF 169
Cdd:COG1132 430 IRENIRYgrpDATDEEVE-------EAAKA---AQAHEfIEAlpdgydTVVGERgvnlSGGQRQRIAIARALLKDPPILI 499
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 170 ADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIV 224
Cdd:COG1132 500 LDEATSALDTETEALIQEALERLMKGRTTIV-IAHRLSTIRNADRILVLDDGRIV 553
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
7-223 |
5.38e-25 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 98.70 E-value: 5.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 7 VKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrl 86
Cdd:cd03248 12 VKFQNVTFAYPTRPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHS--- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 87 tEIGFIFQQSNLLRNlNLFDNIilsAY-LAKCESKKIVnkrALELMENMG--ISDIASHYITEA-------SGGQLQRVS 156
Cdd:cd03248 89 -KVSLVGQEPVLFAR-SLQDNI---AYgLQSCSFECVK---EAAQKAHAHsfISELASGYDTEVgekgsqlSGGQKQRVA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRgGTTIMLVTHDVKVAAKTERILFMADGEI 223
Cdd:cd03248 161 IARALIRNPQVLILDEATSALDAESEQQVQQALYDWPE-RRTVLVIAHRLSTVERADQILVLDGGRI 226
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
25-220 |
6.62e-25 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 97.94 E-value: 6.62e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGM---DQMSSGSVKIDSKELSCMKEEAlaklRltEIGFIFQQSNLLRN 101
Cdd:COG4136 17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTlspAFSASGEVLLNGRRLTALPAEQ----R--RIGILFQDDLLFPH 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 102 LNLFDNII--LSAYLAKCESKkivnKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNL 179
Cdd:COG4136 91 LSVGENLAfaLPPTIGRAQRR----ARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDA 166
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446644341 180 KSTEEVMQILLN--INRGGTTIMlVTHDVKVAAKTERILFMAD 220
Cdd:COG4136 167 ALRAQFREFVFEqiRQRGIPALL-VTHDEEDAPAAGRVLDLGN 208
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
19-226 |
6.89e-25 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 98.46 E-value: 6.89e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 19 NTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrltEIGFIFQQSNL 98
Cdd:cd03253 11 DPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRR----AIGVVPQDTVL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 99 LrNLNLFDNI-----------ILSAYLAKCESKKIVN----------KRALELmenmgisdiashyiteaSGGQLQRVSI 157
Cdd:cd03253 87 F-NDTIGYNIrygrpdatdeeVIEAAKAAQIHDKIMRfpdgydtivgERGLKL-----------------SGGEKQRVAI 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 158 CRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:cd03253 149 ARAILKNPPILLLDEATSALDTHTEREIQAALRDVSKGRTTIV-IAHRLSTIVNADKIIVLKDGRIVER 216
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
23-224 |
1.30e-24 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 102.05 E-value: 1.30e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLL-----YNISGMDQmsSGSVKIDSK--ELSCMKEEAlaklrlteiGFIFQQ 95
Cdd:TIGR00955 39 HLLKNVSGVAKPGELLAVMGSSGAGKTTLMnalafRSPKGVKG--SGSVLLNGMpiDAKEMRAIS---------AYVQQD 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 96 SNLLRNLNLFDNIILSAYL--AKCESKKIVNKRALELMENMGISDIASHYITEA------SGGQLQRVSICRALINNPNI 167
Cdd:TIGR00955 108 DLFIPTLTVREHLMFQAHLrmPRRVTKKEKRERVDEVLQALGLRKCANTRIGVPgrvkglSGGERKRLAFASELLTDPPL 187
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 168 IFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHD--VKVAAKTERILFMADGEIV 224
Cdd:TIGR00955 188 LFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQpsSELFELFDKIILMAEGRVA 246
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
24-224 |
1.31e-24 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 98.58 E-value: 1.31e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKE----EALaKLRlTEIGFIFQQSNLL 99
Cdd:PRK14246 25 ILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKDifqiDAI-KLR-KEVGMVFQQPNPF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 100 RNLNLFDNIILSAYLAKCESKKIVNKRALELMENMG----ISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTG 175
Cdd:PRK14246 103 PHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGlwkeVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTS 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446644341 176 ALNLKSTEEVMQILLNInRGGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK14246 183 MIDIVNSQAIEKLITEL-KNEIAIVIVSHNPQQVARvADYVAFLYNGELV 231
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
5-226 |
2.76e-24 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 94.80 E-value: 2.76e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkeealakl 84
Cdd:cd03216 1 LELRGITKRF---GGV--KALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVS---------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteigfifqqsnllrnlnlFDNIilsaylakceskkivnKRALELmenmGISdiashYITEASGGQLQRVSICRALINN 164
Cdd:cd03216 66 --------------------FASP----------------RDARRA----GIA-----MVYQLSVGERQMVEIARALARN 100
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIVSE 226
Cdd:cd03216 101 ARLLILDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDeVFEIADRVTVLRDGRVVGT 163
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
21-223 |
3.23e-24 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 96.47 E-value: 3.23e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 21 NYHVLK-NIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkeeALAKLRlTEIGFIFQQSNLL 99
Cdd:TIGR01277 9 EYEHLPmEFDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHT-----GLAPYQ-RPVSMLFQENNLF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 100 RNLNLFDNIIL----SAYLAKCESKKIVnkralELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTG 175
Cdd:TIGR01277 83 AHLTVRQNIGLglhpGLKLNAEQQEKVV-----DAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFS 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446644341 176 ALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAKT-ERILFMADGEI 223
Cdd:TIGR01277 158 ALDPLLREEMLALVKQLcSERQRTLLMVTHHLSDARAIaSQIAVVSQGKI 207
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
5-215 |
4.63e-24 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 95.62 E-value: 4.63e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAkl 84
Cdd:COG4133 3 LEAENLSCRR--GERL---LFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRR-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rltEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIvnkRALELMENMGISDIASHYITEASGGQLQRVSICRALINN 164
Cdd:COG4133 76 ---RLAYLGHADGLKPELTVRENLRFWAALYGLRADRE---AIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSP 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERI 215
Cdd:COG4133 150 APLWLLDEPFTALDAAGVALLAELIAAHLARGGAVLLTTHQPLELAAARVL 200
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-223 |
6.29e-24 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 94.42 E-value: 6.29e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVnktysmdgnTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAL 81
Cdd:cd03215 2 EPVLEVRGL---------SVKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKLRlteIGFI---FQQSNLLRNLNLFDNIILSAYLakceskkivnkralelmenmgisdiashyiteaSGGQLQRVSIC 158
Cdd:cd03215 73 IRAG---IAYVpedRKREGLVLDLSVAENIALSSLL---------------------------------SGGNQQKVVLA 116
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 159 RALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEI 223
Cdd:cd03215 117 RWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAGKAVLLISSELdELLGLCDRILVMYEGRI 182
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
25-224 |
1.44e-23 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 98.18 E-value: 1.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRLTEIGFIFQQSNLLRNLNL 104
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMPHMTV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 105 FDNIILSAYLAKCESKKiVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEE 184
Cdd:PRK10070 124 LDNTAFGMELAGINAEE-RREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTE 202
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446644341 185 VMQILLNIN-RGGTTIMLVTHDVKVAAKT-ERILFMADGEIV 224
Cdd:PRK10070 203 MQDELVKLQaKHQRTIVFISHDLDEAMRIgDRIAIMQNGEVV 244
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
4-224 |
1.45e-23 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 98.99 E-value: 1.45e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGN----TNYHV--LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQmSSGSVKIDSKELSCMK 77
Cdd:COG4172 275 LLEARDLKVWFPIKRGlfrrTVGHVkaVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGLS 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 78 EEALAKLRlTEIGFIFQQ--SNLLRNLNLFDnII---LSAyLAKCESKKIVNKRALELMENMGIS-DIASHYITEASGGQ 151
Cdd:COG4172 354 RRALRPLR-RRMQVVFQDpfGSLSPRMTVGQ-IIaegLRV-HGPGLSAAERRARVAEALEEVGLDpAARHRYPHEFSGGQ 430
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 152 LQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNIN-RGGTTIMLVTHDVKV-AAKTERILFMADGEIV 224
Cdd:COG4172 431 RQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQrEHGLAYLFISHDLAVvRALAHRVMVMKDGKVV 505
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
4-226 |
1.58e-23 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 96.73 E-value: 1.58e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGM----DQMSSGSVKIDSKELSCMKEE 79
Cdd:PRK11022 3 LLNVDKLSVHFG-DESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLidypGRVMAEKLEFNGQDLQRISEK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 ALAKLRLTEIGFIFQQSnlLRNLN----LFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASH---YITEASGGQL 152
Cdd:PRK11022 82 ERRNLVGAEVAMIFQDP--MTSLNpcytVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRldvYPHQLSGGMS 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 153 QRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVK-VAAKTERILFMADGEIVSE 226
Cdd:PRK11022 160 QRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKeNMALVLITHDLAlVAEAAHKIIVMYAGQVVET 235
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
28-249 |
1.67e-23 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 97.10 E-value: 1.67e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 28 IDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscmkEEALAKLRLT----EIGFIFQQSNLLRNLN 103
Cdd:TIGR02142 16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTL----FDSRKGIFLPpekrRIGYVFQEARLFPHLS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVNKRALELMenmGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTE 183
Cdd:TIGR02142 92 VRGNLRYGMKRARPSERRISFERVIELL---GIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKY 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 184 EVMQILLNINRG-GTTIMLVTHDV-KVAAKTERILFMADGEIVSEiqlGKLrnDDLKAReeKLLNWLA 249
Cdd:TIGR02142 169 EILPYLERLHAEfGIPILYVSHSLqEVLRLADRVVVLEDGRVAAA---GPI--AEVWAS--PDLPWLA 229
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1-226 |
1.88e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 95.93 E-value: 1.88e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSMDGNTNYhvLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCmkeEA 80
Cdd:PRK13642 1 MNKILEVENLVFKYEKESDVNQ--LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTA---EN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLRlTEIGFIFQQ-SNLLRNLNLFDNIILSAYLAKCESKKIVnKRALELMENMGISDIASHYITEASGGQLQRVSICR 159
Cdd:PRK13642 76 VWNLR-RKIGMVFQNpDNQFVGATVEDDVAFGMENQGIPREEMI-KRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAG 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 160 ALINNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:PRK13642 154 IIALRPEIIILDESTSMLDPTGRQEIMRVIHEIkEKYQLTVLSITHDLDEAASSDRILVMKAGEIIKE 221
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-233 |
1.99e-23 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 95.29 E-value: 1.99e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMS-----SGSVKIDSKELSC 75
Cdd:PRK14267 1 MKFAIETVNLRVYYG-----SNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNIYS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 76 MKEEALAKLRltEIGFIFQQSNLLRNLNLFDNIILSAYLAK-CESKKIVNKRALELMENMG----ISDIASHYITEASGG 150
Cdd:PRK14267 76 PDVDPIEVRR--EVGMVFQYPNPFPHLTIYDNVAIGVKLNGlVKSKKELDERVEWALKKAAlwdeVKDRLNDYPSNLSGG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 151 QLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNInRGGTTIMLVTHDVKVAAK-TERILFMADGEIvseIQL 229
Cdd:PRK14267 154 QRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFEL-KKEYTIVLVTHSPAQAARvSDYVAFLYLGKL---IEV 229
|
....
gi 446644341 230 GKLR 233
Cdd:PRK14267 230 GPTR 233
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
5-224 |
2.74e-23 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 94.10 E-value: 2.74e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMkeeALAKL 84
Cdd:cd03244 3 IEFKNVSLRYRPNLPP---VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKI---GLHDL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNL----LR-NLNLF----DNIILSAyLAKCESKKIVNKRA--LELMENMGISDIashyiteaSGGQLQ 153
Cdd:cd03244 77 R-SRISIIPQDPVLfsgtIRsNLDPFgeysDEELWQA-LERVGLKEFVESLPggLDTVVEEGGENL--------SVGQRQ 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNlKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:cd03244 147 LLCLARALLRKSKILVLDEATASVD-PETDALIQKTIREAFKDCTVLTIAHRLDTIIDSDRILVLDKGRVV 216
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
4-227 |
3.23e-23 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 95.95 E-value: 3.23e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYS-----MDGNTNY-HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMK 77
Cdd:COG4608 7 LLEVRDLKKHFPvrgglFGRTVGVvKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 78 EEALAKLRLtEIGFIFQ--QSNLLRNLNLFDniILSAYLA--KCESKKIVNKRALELMENMGIS-DIASHYITEASGGQL 152
Cdd:COG4608 87 GRELRPLRR-RMQMVFQdpYASLNPRMTVGD--IIAEPLRihGLASKAERRERVAELLELVGLRpEHADRYPHEFSGGQR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 153 QRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHD---VK-VAaktERILFMADGEIVsEI 227
Cdd:COG4608 164 QRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLqDELGLTYLFISHDlsvVRhIS---DRVAVMYLGKIV-EI 239
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
5-226 |
4.11e-23 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 97.57 E-value: 4.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAL--- 81
Cdd:TIGR03269 1 IEVKNLTKKFD-----GKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYEPTSGRIIYHVALCEKCGYVerp 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 -----------AKLRLTEIGFI-----------------FQQS-NLLRNLNLFDNIILSAYLAKCESKKIVnKRALELME 132
Cdd:TIGR03269 76 skvgepcpvcgGTLEPEEVDFWnlsdklrrrirkriaimLQRTfALYGDDTVLDNVLEALEEIGYEGKEAV-GRAVDLIE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 133 NMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLN-INRGGTTIMLVTHDVKVAAK 211
Cdd:TIGR03269 155 MVQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEaVKASGISMVLTSHWPEVIED 234
|
250
....*....|....*.
gi 446644341 212 -TERILFMADGEIVSE 226
Cdd:TIGR03269 235 lSDKAIWLENGEIKEE 250
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
5-218 |
4.14e-23 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 97.36 E-value: 4.14e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdGNTNyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkeEALAKL 84
Cdd:TIGR02857 322 LEFSGVSVAYP--GRRP--ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLA----DADADS 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIGFIFQQSNLLrNLNLFDNIILsaylAKCESKKIVNKRALELMENMG-ISDIASHYITEA-------SGGQLQRVS 156
Cdd:TIGR02857 394 WRDQIAWVPQHPFLF-AGTIAENIRL----ARPDASDAEIREALERAGLDEfVAALPQGLDTPIgeggaglSGGQAQRLA 468
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTImLVTHDVKVAAKTERILFM 218
Cdd:TIGR02857 469 LARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGRTVL-LVTHRLALAALADRIVVL 529
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
27-221 |
5.59e-23 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 93.90 E-value: 5.59e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 27 NIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRLTEigfIFQQSNLLRNLNLFD 106
Cdd:PRK11300 23 NVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARMGVVR---TFQHVRLFREMTVIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 107 NI-----------ILSAYLA-----KCESKKIvnKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFA 170
Cdd:PRK11300 100 NLlvaqhqqlktgLFSGLLKtpafrRAESEAL--DRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILML 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446644341 171 DEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVK-VAAKTERILFMADG 221
Cdd:PRK11300 178 DEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKlVMGISDRIYVVNQG 230
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
25-224 |
6.19e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 94.34 E-value: 6.19e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScMKEEALAKLRlTEIGFIFQQSnllrNLNL 104
Cdd:PRK13637 23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDIT-DKKVKLSDIR-KKVGLVFQYP----EYQL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 105 FDNIILS--AYLAK--CESKKIVNKRALELMENMGIS--DIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALN 178
Cdd:PRK13637 97 FEETIEKdiAFGPInlGLSEEEIENRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLD 176
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446644341 179 LKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK13637 177 PKGRDEILNKIKELHKEyNMTIILVSHSMEDVAKlADRIIVMNKGKCE 224
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
4-173 |
6.74e-23 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 93.17 E-value: 6.74e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSC--MKEEAl 81
Cdd:COG1137 3 TLEAENLVKSYG-----KRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHlpMHKRA- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 aklRLTeIGFIFQQSNLLRNLNLFDNIILSAYLAKcESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRAL 161
Cdd:COG1137 77 ---RLG-IGYLPQEASIFRKLTVEDNILAVLELRK-LSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARAL 151
|
170
....*....|..
gi 446644341 162 INNPNIIFADEP 173
Cdd:COG1137 152 ATNPKFILLDEP 163
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
5-239 |
7.96e-23 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 92.97 E-value: 7.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:TIGR03410 1 LEVSNLNVYY---GQS--HILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERARA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rltEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVnKRALEL------MENMGISDIashyiteaSGGQLQRVSIC 158
Cdd:TIGR03410 76 ---GIAYVPQGREIFPRLTVEENLLTGLAALPRRSRKIP-DEIYELfpvlkeMLGRRGGDL--------SGGQQQQLAIA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 159 RALINNPNIIFADEPTGALNLKSTEEVMQILLNIN-RGGTTIMLVTHDVKVA-AKTERILFMADGEIVSEIQLGKLRNDD 236
Cdd:TIGR03410 144 RALVTRPKLLLLDEPTEGIQPSIIKDIGRVIRRLRaEGGMAILLVEQYLDFArELADRYYVMERGRVVASGAGDELDEDK 223
|
...
gi 446644341 237 LKA 239
Cdd:TIGR03410 224 VRR 226
|
|
| anch_rpt_ABC |
TIGR03771 |
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ... |
30-234 |
1.41e-22 |
|
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 92.22 E-value: 1.41e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 30 LEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKElscmkeealAKLRLTEIGFIFQQSNLLRNLNL-FDNI 108
Cdd:TIGR03771 1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGAS---------PGKGWRHIGYVPQRHEFAWDFPIsVAHT 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 109 ILSA---YLAKCESKKIVNKRAL-ELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEE 184
Cdd:TIGR03771 72 VMSGrtgHIGWLRRPCVADFAAVrDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQEL 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446644341 185 VMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIVSEIQLGKLRN 234
Cdd:TIGR03771 152 LTELFIELAGAGTAILMTTHDLAQAMATCDRVVLLNGRVIADGTPQQLQD 201
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
5-204 |
2.08e-22 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 92.89 E-value: 2.08e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:PRK13649 3 INLQNVSYTYQAGTPFEGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIGFIFQqsnlLRNLNLFDNIILSAYLAKCE----SKKIVNKRALELMENMGIS-DIASHYITEASGGQLQRVSICR 159
Cdd:PRK13649 83 IRKKVGLVFQ----FPESQLFEETVLKDVAFGPQnfgvSQEEAEALAREKLALVGISeSLFEKNPFELSGGQMRRVAIAG 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446644341 160 ALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTH 204
Cdd:PRK13649 159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTH 203
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
22-224 |
2.23e-22 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 91.95 E-value: 2.23e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 22 YHVLK-NIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMkeeALAKlrlTEIGFIFQQSNLLR 100
Cdd:PRK10771 11 YHHLPmRFDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTT---PPSR---RPVSMLFQENNLFS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 NLNLFDNIILSAYLA-KCESKKivnKRALELM-ENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALN 178
Cdd:PRK10771 85 HLTVAQNIGLGLNPGlKLNAAQ---REKLHAIaRQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALD 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446644341 179 LKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK10771 162 PALRQEMLTLVSQVcQERQLTLLMVSHSLEDAARiAPRSLVVADGRIA 209
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-237 |
2.52e-22 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 95.24 E-value: 2.52e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEA 80
Cdd:PRK09700 2 ATPYISMAGIGKSFG-----PVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLrltEIGFIFQQSNLLRNLNLFDNIilsaYLAKCESKKI----------VNKRALELMENMGISDIASHYITEASGG 150
Cdd:PRK09700 77 AAQL---GIGIIYQELSVIDELTVLENL----YIGRHLTKKVcgvniidwreMRVRAAMMLLRVGLKVDLDEKVANLSIS 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 151 QLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIVSEIQL 229
Cdd:PRK09700 150 HKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAeIRRICDRYTVMKDGSSVCSGMV 229
|
....*...
gi 446644341 230 GKLRNDDL 237
Cdd:PRK09700 230 SDVSNDDI 237
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
1-221 |
2.57e-22 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 93.64 E-value: 2.57e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSM-DGNTNyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGM---DQMSSGSVKIDSKELSCM 76
Cdd:PRK09473 9 ADALLDVKDLRVTFSTpDGDVT--AVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLlaaNGRIGGSATFNGREILNL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 77 KEEALAKLRLTEIGFIFQQSnlLRNLN--------LFDNIILSAYLAKC----ESKKIVNKRAL-ELMENMGIsdiashY 143
Cdd:PRK09473 87 PEKELNKLRAEQISMIFQDP--MTSLNpymrvgeqLMEVLMLHKGMSKAeafeESVRMLDAVKMpEARKRMKM------Y 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 144 ITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAKT-ERILFMADG 221
Cdd:PRK09473 159 PHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGIcDKVLVMYAG 238
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
14-224 |
2.81e-22 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 95.30 E-value: 2.81e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 14 YSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMdqMS-SGSVKIDSKELScmkEEALAKLRlTEIGFI 92
Cdd:PRK11174 358 LSPDGKT---LAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGF--LPyQGSLKINGIELR---ELDPESWR-KHLSWV 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 93 FQQSNLLRNlNLFDNIILSAYLAKCEskkivnkRALELMENMGISDIAS-------HYITEA----SGGQLQRVSICRAL 161
Cdd:PRK11174 429 GQNPQLPHG-TLRDNVLLGNPDASDE-------QLQQALENAWVSEFLPllpqgldTPIGDQaaglSVGQAQRLALARAL 500
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIV 224
Cdd:PRK11174 501 LQPCQLLLLDEPTASLDAHSEQLVMQALNAASRRQTTLM-VTHQLEDLAQWDQIWVMQDGQIV 562
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-226 |
5.62e-22 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 94.32 E-value: 5.62e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLyNI-SGMDQMSSGSVKIDSKELScMKE- 78
Cdd:COG3845 2 MPPALELRGITKRF---GGV--VANDDVSLTVRPGEIHALLGENGAGKSTLM-KIlYGLYQPDSGEILIDGKPVR-IRSp 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 79 -EALAKlrltEIGFIFQQSNLLRNLNLFDNIILSAYLAKCE--SKKIVNKRALELMENMG--------ISDIashyitea 147
Cdd:COG3845 75 rDAIAL----GIGMVHQHFMLVPNLTVAENIVLGLEPTKGGrlDRKAARARIRELSERYGldvdpdakVEDL-------- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 148 SGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIVSE 226
Cdd:COG3845 143 SVGEQQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITHKLReVMAIADRVTVLRRGKVVGT 222
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
5-223 |
6.92e-22 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 92.60 E-value: 6.92e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmDGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKeealAKL 84
Cdd:PRK11650 4 LKLQAVRKSY--DGKT--QVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELE----PAD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RltEIGFIFQQSNLLRNLNLFDNIilsAY------LAKCESKKIVNK--RALELMEnmgisdiashYIT----EASGGQL 152
Cdd:PRK11650 76 R--DIAMVFQNYALYPHMSVRENM---AYglkirgMPKAEIEERVAEaaRILELEP----------LLDrkprELSGGQR 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 153 QRVSICRALINNPNIIFADEPtgaL-NLKSTEEVmQILLNIN----RGGTTIMLVTHDvKVAAKT--ERILFMADGEI 223
Cdd:PRK11650 141 QRVAMGRAIVREPAVFLFDEP---LsNLDAKLRV-QMRLEIQrlhrRLKTTSLYVTHD-QVEAMTlaDRVVVMNGGVA 213
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
8-221 |
8.00e-22 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 90.08 E-value: 8.00e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 8 KQVNKTYSMDGnTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRLT 87
Cdd:cd03290 1 VQVTNGYFSWG-SGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 88 EIGFIFQQSNLLrNLNLFDNIILSAYLAKCESKKIVNKRALE----LMENMGISDIASHYITeASGGQLQRVSICRALIN 163
Cdd:cd03290 80 SVAYAAQKPWLL-NATVEENITFGSPFNKQRYKAVTDACSLQpdidLLPFGDQTEIGERGIN-LSGGQRQRICVARALYQ 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQ--ILLNINRGGTTIMLVTHDVKVAAKTERILFMADG 221
Cdd:cd03290 158 NTNIVFLDDPFSALDIHLSDHLMQegILKFLQDDKRTLVLVTHKLQYLPHADWIIAMKDG 217
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
4-226 |
8.42e-22 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 90.84 E-value: 8.42e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsmdGNTNyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAK 83
Cdd:PRK11231 2 TLRTENLTVGY---GTKR--ILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 lrltEIGFIFQQsnLL--------------RN--LNLFDNiiLSAylakcESKKIVNKRalelMENMGISDIASHYITEA 147
Cdd:PRK11231 77 ----RLALLPQH--HLtpegitvrelvaygRSpwLSLWGR--LSA-----EDNARVNQA----MEQTRINHLADRRLTDL 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 148 SGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK11231 140 SGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRyCDHLVVLANGHVMAQ 219
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
24-224 |
1.38e-21 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 89.91 E-value: 1.38e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLL------YNISgmdqmsSGSVKIDSKElscMKEEALAKLRlTEIGFIFQQSN 97
Cdd:cd03249 18 ILKGLSLTIPPGKTVALVGSSGCGKSTVVsllerfYDPT------SGEILLDGVD---IRDLNLRWLR-SQIGLVSQEPV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 98 LLrNLNLFDNIILSAYLAKCESKKIVNKRAlelmenmGISD-IAS---HYITEA-------SGGQLQRVSICRALINNPN 166
Cdd:cd03249 88 LF-DGTIAENIRYGKPDATDEEVEEAAKKA-------NIHDfIMSlpdGYDTLVgergsqlSGGQKQRIAIARALLRNPK 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 167 IIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIV 224
Cdd:cd03249 160 ILLLDEATSALDAESEKLVQEALDRAMKGRTTIV-IAHRLSTIRNADLIAVLQNGQVV 216
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-240 |
1.67e-21 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 90.94 E-value: 1.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkEEALAK 83
Cdd:COG4152 1 MLELKGLTKRFG-----DKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLD---PEDRRR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 lrlteIGFIFQQSNLLRNLNLFDNIIlsaYLA--KCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRAL 161
Cdd:COG4152 73 -----IGYLPEERGLYPKMKVGEQLV---YLArlKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAAL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSEiqlGKLrnDDLKAR 240
Cdd:COG4152 145 LHDPELLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEElCDRIVIINKGRKVLS---GSV--DEIRRQ 219
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
23-224 |
1.67e-21 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 93.00 E-value: 1.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRlTEIGFIFQQ--SNLLR 100
Cdd:PRK10261 338 HAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALR-RDIQFIFQDpyASLDP 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 NLNLFDNIILSAYLAKCESKKIVNKRALELMENMGI-SDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNL 179
Cdd:PRK10261 417 RQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDV 496
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446644341 180 KSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK10261 497 SIRGQIINLLLDLQRDfGIAYLFISHDMAVVERiSHRVAVMYLGQIV 543
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
24-223 |
2.60e-21 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 92.41 E-value: 2.60e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrltEIGFIFQQSNLL---- 99
Cdd:TIGR01842 333 TLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGK----HIGYLPQDVELFpgtv 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 100 -RNLNLFDNIIlsaylakcESKKIVNKRAL----ELMEN--MGI-SDIASHYITeASGGQLQRVSICRALINNPNIIFAD 171
Cdd:TIGR01842 409 aENIARFGENA--------DPEKIIEAAKLagvhELILRlpDGYdTVIGPGGAT-LSGGQRQRIALARALYGDPKLVVLD 479
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446644341 172 EPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEI 223
Cdd:TIGR01842 480 EPNSNLDEEGEQALANAIKALKARGITVVVITHRPSLLGCVDKILVLQDGRI 531
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
18-226 |
3.98e-21 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 89.28 E-value: 3.98e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 18 GNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrltEIGFIFQQSN 97
Cdd:PRK10253 16 GYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVAR----RIGLLAQNAT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 98 LLRNLNLFDNIILSAYLA-------KCESKKIVNKRalelMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFA 170
Cdd:PRK10253 92 TPGDITVQELVARGRYPHqplftrwRKEDEEAVTKA----MQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 171 DEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK10253 168 DEPTTWLDISHQIDLLELLSELNReKGYTLAAVLHDLNQACRyASHLIALREGKIVAQ 225
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
23-234 |
4.89e-21 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 89.76 E-value: 4.89e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKID----SKElscmkEEALAKlrltEIGFIF-QQSN 97
Cdd:COG4586 36 EAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLgyvpFKR-----RKEFAR----RIGVVFgQRSQ 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 98 LLRNLNLFDNIILSAYLAKCeSKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGAL 177
Cdd:COG4586 107 LWWDLPAIDSFRLLKAIYRI-PDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGL 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 178 NLKSTEEVMQILLNINR-GGTTIMLVTHDVK-VAAKTERILFMADGEIVSEIQLGKLRN 234
Cdd:COG4586 186 DVVSKEAIREFLKEYNReRGTTILLTSHDMDdIEALCDRVIVIDHGRIIYDGSLEELKE 244
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
5-224 |
6.10e-21 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 91.42 E-value: 6.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL 84
Cdd:PRK11160 339 LTLNNVSFTYP---DQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlteIGFIFQQSNLLrNLNLFDNIILSAYLAKCES-KKIVNKRALE-LMENMGISDIashYITEA----SGGQLQRVSIC 158
Cdd:PRK11160 416 ----ISVVSQRVHLF-SATLRDNLLLAAPNASDEAlIEVLQQVGLEkLLEDDKGLNA---WLGEGgrqlSGGEQRRLGIA 487
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 159 RALINNPNIIFADEPTGALNlKSTE-EVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIV 224
Cdd:PRK11160 488 RALLHDAPLLLLDEPTEGLD-AETErQILELLAEHAQNKTVLM-ITHRLTGLEQFDRICVMDNGQII 552
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
24-235 |
1.13e-20 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 90.55 E-value: 1.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAklrlTEIGfIFQQSNLLRNLN 103
Cdd:TIGR00958 496 VLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLH----RQVA-LVGQEPVLFSGS 570
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIilsAY-LAKCESKKIVNKRALELMENMgISDIASHYITEA-------SGGQLQRVSICRALINNPNIIFADEPTG 175
Cdd:TIGR00958 571 VRENI---AYgLTDTPDEEIMAAAKAANAHDF-IMEFPNGYDTEVgekgsqlSGGQKQRIAIARALVRKPRVLILDEATS 646
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 176 ALNLKSTEEVMQillNINRGGTTIMLVTHDVKVAAKTERILFMADGEIVSEIQLGKLRND 235
Cdd:TIGR00958 647 ALDAECEQLLQE---SRSRASRTVLLIAHRLSTVERADQILVLKKGSVVEMGTHKQLMED 703
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
24-224 |
1.40e-20 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 90.19 E-value: 1.40e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLrlteIGFIFQQSNLlrnln 103
Cdd:COG4618 347 ILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRH----IGYLPQDVEL----- 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 lFD-----NIilsAYLAKCESKKIVN--KRAlelmenmGISD-IAS------HYITEA----SGGQLQRVSICRALINNP 165
Cdd:COG4618 418 -FDgtiaeNI---ARFGDADPEKVVAaaKLA-------GVHEmILRlpdgydTRIGEGgarlSGGQRQRIGLARALYGDP 486
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 166 NIIFADEPTGalNLKSTEE--VMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:COG4618 487 RLVVLDEPNS--NLDDEGEaaLAAAIRALKARGATVVVITHRPSLLAAVDKLLVLRDGRVQ 545
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-224 |
1.72e-20 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 87.29 E-value: 1.72e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSK-----ELSC 75
Cdd:PRK11701 3 DQPLLSVRGLTKLYG-----PRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRdgqlrDLYA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 76 MKEEALAKLRLTEIGFIFQ--QSNLLRNLNLFDNII--LSAYLAKCESKkiVNKRALELMENMgisDIASHYITEA---- 147
Cdd:PRK11701 78 LSEAERRRLLRTEWGFVHQhpRDGLRMQVSAGGNIGerLMAVGARHYGD--IRATAGDWLERV---EIDAARIDDLpttf 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 148 SGGQLQRVSICRALINNPNIIFADEPTGALNLksteEVMQILLNINRG-----GTTIMLVTHDVKVAAK-TERILFMADG 221
Cdd:PRK11701 153 SGGMQQRLQIARNLVTHPRLVFMDEPTGGLDV----SVQARLLDLLRGlvrelGLAVVIVTHDLAVARLlAHRLLVMKQG 228
|
...
gi 446644341 222 EIV 224
Cdd:PRK11701 229 RVV 231
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
24-222 |
2.85e-20 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 85.60 E-value: 2.85e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKelscmkeealaklrlteIGFIFQQSnLLRNLN 103
Cdd:cd03250 20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS-----------------IAYVSQEP-WIQNGT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVNKRALEL-MENM-----------GISdiashyiteASGGQLQRVSICRALINNPNIIFAD 171
Cdd:cd03250 82 IRENILFGKPFDEERYEKVIKACALEPdLEILpdgdlteigekGIN---------LSGGQKQRISLARAVYSDADIYLLD 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446644341 172 EPTGALNLKSTEEVMQ-ILLNINRGGTTIMLVTHDVKVAAKTERILFMADGE 222
Cdd:cd03250 153 DPLSAVDAHVGRHIFEnCILGLLLNNKTRILVTHQLQLLPHADQIVVLDNGR 204
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
27-224 |
3.12e-20 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 88.23 E-value: 3.12e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 27 NIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKI------DSKELSCMKEEalaKLRlteIGFIFQQSNLLR 100
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLggevlqDSARGIFLPPH---RRR---IGYVFQEARLFP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 NLNLFDNIilsAYLAKcESKKIVNKRAL-ELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNL 179
Cdd:COG4148 91 HLSVRGNL---LYGRK-RAPRAERRISFdEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDL 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446644341 180 KSTEEVMQILLNINR-GGTTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:COG4148 167 ARKAEILPYLERLRDeLDIPILYVSHSLDeVARLADHVVLLEQGRVV 213
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
2-227 |
8.17e-20 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 87.77 E-value: 8.17e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVnktySMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAL 81
Cdd:COG3845 255 EVVLEVENL----SVRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRER 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKLRlteIGFI---FQQSNLLRNLNLFDNIILSAYLAKCESKKI------VNKRALELMENMGISdiASHYITEA---SG 149
Cdd:COG3845 331 RRLG---VAYIpedRLGRGLVPDMSVAENLILGRYRRPPFSRGGfldrkaIRAFAEELIEEFDVR--TPGPDTPArslSG 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 150 GQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHD----VKVAaktERILFMADGEIVS 225
Cdd:COG3845 406 GNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDldeiLALS---DRIAVMYEGRIVG 482
|
..
gi 446644341 226 EI 227
Cdd:COG3845 483 EV 484
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
25-204 |
6.12e-19 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 85.35 E-value: 6.12e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMK-EEALAklrlTEIGFIFQQSNLLRNLN 103
Cdd:PRK11288 20 LDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFAStTAALA----AGVAIIYQELHLVPEMT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCE--SKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKS 181
Cdd:PRK11288 96 VAENLYLGQLPHKGGivNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSARE 175
|
170 180
....*....|....*....|...
gi 446644341 182 TEEVMQILLNINRGGTTIMLVTH 204
Cdd:PRK11288 176 IEQLFRVIRELRAEGRVILYVSH 198
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
24-241 |
6.77e-19 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 83.28 E-value: 6.77e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRlTEIGFIFQQSNLLRNLN 103
Cdd:PRK11831 22 IFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVR-KRMSMLFQSGALFTDMN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIilsAYLAKCESK---KIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEP------- 173
Cdd:PRK11831 101 VFDNV---AYPLREHTQlpaPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPfvgqdpi 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 174 TGALNLKSTEEVMQILlninrgGTTIMLVTHDV-KVAAKTERILFMADGEIVSEIQLGKLR-NDDLKARE 241
Cdd:PRK11831 178 TMGVLVKLISELNSAL------GVTCVVVSHDVpEVLSIADHAYIVADKKIVAHGSAQALQaNPDPRVRQ 241
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
23-224 |
7.02e-19 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 84.19 E-value: 7.02e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGM---------DQMSsgsvkIDSKELSCMKEEALAKLRLTEIGFIF 93
Cdd:COG4170 21 KAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGItkdnwhvtaDRFR-----WNGIDLLKLSPRERRKIIGREIAMIF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 94 Q--QSNLLRNLNLFDNIILSAYLAKCESK-----KIVNKRALELMENMGISD---IASHYITEASGGQLQRVSICRALIN 163
Cdd:COG4170 96 QepSSCLDPSAKIGDQLIEAIPSWTFKGKwwqrfKWRKKRAIELLHRVGIKDhkdIMNSYPHELTEGECQKVMIAMAIAN 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDV-KVAAKTERILFMADGEIV 224
Cdd:COG4170 176 QPRLLIADEPTNAMESTTQAQIFRLLARLNQlQGTSILLISHDLeSISQWADTITVLYCGQTV 238
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
24-205 |
1.79e-18 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 83.95 E-value: 1.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLrlteIGFIFQQSNLLrNLN 103
Cdd:TIGR02868 350 VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRR----VSVCAQDAHLF-DTT 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESkkivnkrALELMENMGISDI-------ASHYITEA----SGGQLQRVSICRALINNPNIIFADE 172
Cdd:TIGR02868 425 VRENLRLARPDATDEE-------LWAALERVGLADWlralpdgLDTVLGEGgarlSGGERQRLALARALLADAPILLLDE 497
|
170 180 190
....*....|....*....|....*....|...
gi 446644341 173 PTGALNLKSTEEVMQILLNINRGGTTImLVTHD 205
Cdd:TIGR02868 498 PTEHLDAETADELLEDLLAALSGRTVV-LITHH 529
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
4-245 |
2.24e-18 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 83.53 E-value: 2.24e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVnktysmdgnTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMK-EEALA 82
Cdd:COG1129 256 VLEVEGL---------SVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSpRDAIR 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KlrlteiGFIF-----QQSNLLRNLNLFDNIILSAyLAKCESKKIVNKR-----ALELMENMGI--SDIASHyITEASGG 150
Cdd:COG1129 327 A------GIAYvpedrKGEGLVLDLSIRENITLAS-LDRLSRGGLLDRRreralAEEYIKRLRIktPSPEQP-VGNLSGG 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 151 QLQRVSICRALINNPNIIFADEPT-----GAlnlKSteEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:COG1129 399 NQQKVVLAKWLATDPKVLILDEPTrgidvGA---KA--EIYRLIRELAAEGKAVIVISSELPeLLGLSDRILVMREGRIV 473
|
250 260
....*....|....*....|.
gi 446644341 225 SEiqlgkLRNDDlkAREEKLL 245
Cdd:COG1129 474 GE-----LDREE--ATEEAIM 487
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
24-223 |
3.58e-18 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 82.97 E-value: 3.58e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKL-----RLTEIGFIFQQSNL 98
Cdd:PRK09536 18 VLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRvasvpQDTSLSFEFDVRQV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 99 LRnlnlfdnIILSAYLAKCESKKIVNKRALE-LMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGAL 177
Cdd:PRK09536 98 VE-------MGRTPHRSRFDTWTETDRAAVErAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASL 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446644341 178 NLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEI 223
Cdd:PRK09536 171 DINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARyCDELVLLADGRV 217
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
5-226 |
5.10e-18 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 79.49 E-value: 5.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKqvNKTYSMDGNtnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMD--QMSSGSVKIDSKELSCMKEEALA 82
Cdd:cd03217 1 LEIK--DLHVSVGGK---EILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITDLPPEERA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KLrltEIGFIFQQ---------SNLLRNLnlfdniilsaylakceskkivnkralelmeNMGIsdiashyiteaSGGQLQ 153
Cdd:cd03217 76 RL---GIFLAFQYppeipgvknADFLRYV------------------------------NEGF-----------SGGEKK 111
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAA--KTERILFMADGEIVSE 226
Cdd:cd03217 112 RNEILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREEGKSVLIITHYQRLLDyiKPDRVHVLYDGRIVKS 186
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-224 |
5.41e-18 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 82.54 E-value: 5.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNKTY-SMDGNTNYHVlKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGS--VKIDSKELSCMKE 78
Cdd:TIGR03269 277 EPIIKVRNVSKRYiSVDRGVVKAV-DNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEvnVRVGDEWVDMTKP 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 79 EALAKLRLTE-IGFIFQQSNLLRNLNLFDNIILSAYLAKceSKKIVNKRALELMENMGISD-----IASHYITEASGGQL 152
Cdd:TIGR03269 356 GPDGRGRAKRyIGILHQEYDLYPHRTVLDNLTEAIGLEL--PDELARMKAVITLKMVGFDEekaeeILDKYPDELSEGER 433
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 153 QRVSICRALINNPNIIFADEPTGALN----LKSTEEVMQILLNINRggtTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:TIGR03269 434 HRVALAQVLIKEPRIVILDEPTGTMDpitkVDVTHSILKAREEMEQ---TFIIVSHDMDfVLDVCDRAALMRDGKIV 507
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
5-224 |
6.80e-18 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 80.11 E-value: 6.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKqvNKTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMD--QMSSGSVKIDSKELSCMKEEALA 82
Cdd:COG0396 1 LEIK--NLHVSVEGKE---ILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPkyEVTSGSILLDGEDILELSPDERA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KLRlteIGFIFQQ---------SNLLRnlnlfdnIILSAYLAKCESKKIVNKRALELMENMGIS-DIASHYITEA-SGGQ 151
Cdd:COG0396 76 RAG---IFLAFQYpveipgvsvSNFLR-------TALNARRGEELSAREFLKLLKEKMKELGLDeDFLDRYVNEGfSGGE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 152 LQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHdvkvaakTERIL---------FMADGE 222
Cdd:COG0396 146 KKRNEILQMLLLEPKLAILDETDSGLDIDALRIVAEGVNKLRSPDRGILIITH-------YQRILdyikpdfvhVLVDGR 218
|
..
gi 446644341 223 IV 224
Cdd:COG0396 219 IV 220
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
10-226 |
6.94e-18 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 80.53 E-value: 6.94e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 10 VNKTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGM-DQMS----SGSVKIDSKELSCMKEEALAKL 84
Cdd:PRK14271 25 VNLTLGFAGKT---VLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMnDKVSgyrySGDVLLGGRSIFNYRDVLEFRR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlteIGFIFQQSNLLrNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEA----SGGQLQRVSICRA 160
Cdd:PRK14271 102 R---VGMLFQRPNPF-PMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAVKDRLSDSpfrlSGGQQQLLCLART 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 161 LINNPNIIFADEPTGALNLKSTEEVMQILLNInRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK14271 178 LAVNPEVLLLDEPTSALDPTTTEKIEEFIRSL-ADRLTVIIVTHNLAQAARiSDRAALFFDGRLVEE 243
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-237 |
1.08e-17 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 81.64 E-value: 1.08e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSK---ELSCMK 77
Cdd:PRK15439 8 APPLLCARSISKQYS-----GVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNpcaRLTPAK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 78 EEALAklrlteIGFIFQQSNLLRNLNLFDNIILSayLAKCESKKivnKRALELMENMGisdiaSHYITEASGGQL----- 152
Cdd:PRK15439 83 AHQLG------IYLVPQEPLLFPNLSVKENILFG--LPKRQASM---QKMKQLLAALG-----CQLDLDSSAGSLevadr 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 153 QRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVSEIQLGK 231
Cdd:PRK15439 147 QIVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLpEIRQLADRISVMRDGTIALSGKTAD 226
|
....*.
gi 446644341 232 LRNDDL 237
Cdd:PRK15439 227 LSTDDI 232
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
11-224 |
1.24e-17 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 81.55 E-value: 1.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 11 NKTYSMDGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrltEIG 90
Cdd:PRK13657 339 DVSFSYDNSR--QGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRR----NIA 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 91 FIFQQSNLLrNLNLFDNIILSAYLAKCESKKIVNKR--ALELMEN--MGISDIASHYITEASGGQLQRVSICRALINNPN 166
Cdd:PRK13657 413 VVFQDAGLF-NRSIEDNIRVGRPDATDEEMRAAAERaqAHDFIERkpDGYDTVVGERGRQLSGGERQRLAIARALLKDPP 491
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 167 IIFADEPTGALNLKSTEEVMQILLNINRGGTTiMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:PRK13657 492 ILILDEATSALDVETEAKVKAALDELMKGRTT-FIIAHRLSTVRNADRILVFDNGRVV 548
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-206 |
1.37e-17 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 79.70 E-value: 1.37e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNK-TYSMDgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSsGSVKIDSK-----ELS 74
Cdd:PRK14258 1 MSKLIPAIKVNNlSFYYD---TQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELE-SEVRVEGRveffnQNI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 75 CMKEEALAKLRlTEIGFIFQQSNLLrNLNLFDNII----LSAYLAKCESKKIVNK--RALELMENmgISDIASHYITEAS 148
Cdd:PRK14258 77 YERRVNLNRLR-RQVSMVHPKPNLF-PMSVYDNVAygvkIVGWRPKLEIDDIVESalKDADLWDE--IKHKIHKSALDLS 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 149 GGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNIN-RGGTTIMLVTHDV 206
Cdd:PRK14258 153 GGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRlRSELTMVIVSHNL 211
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
25-226 |
1.53e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 79.65 E-value: 1.53e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSV---KIDSKELScmKEEALAKLrlteIGFIFQQSNllrn 101
Cdd:PRK13644 18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVlvsGIDTGDFS--KLQGIRKL----VGIVFQNPE---- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 102 lNLFDNIILSAYLA-----KCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGA 176
Cdd:PRK13644 88 -TQFVGRTVEEDLAfgpenLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSM 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446644341 177 LNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:PRK13644 167 LDPDSGIAVLERIKKLHEKGKTIVYITHNLEELHDADRIIVMDRGKIVLE 216
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
5-204 |
1.97e-17 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 77.78 E-value: 1.97e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVnkTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEalakl 84
Cdd:TIGR01189 1 LAARNL--ACSRGERM---LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDE----- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIGFIFQQSNLLRNLNLFDNiiLSAYLAKCESKKIVNKRALELMENMGISDIASHYIteaSGGQLQRVSICRALINN 164
Cdd:TIGR01189 71 PHENILYLGHLPGLKPELSALEN--LHFWAAIHGGAQRTIEDALAAVGLTGFEDLPAAQL---SAGQQRRLALARLWLSR 145
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILL-NINRGGTTImLVTH 204
Cdd:TIGR01189 146 RPLWILDEPTTALDKAGVALLAGLLRaHLARGGIVL-LTTH 185
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
10-225 |
1.99e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 79.67 E-value: 1.99e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 10 VNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKI-DSKELSCMKEEALAKLRLTE 88
Cdd:PRK13645 12 VSYTYAKKTPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVgDYAIPANLKKIKEVKRLRKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 89 IGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMGI-SDIASHYITEASGGQLQRVSICRALINNPNI 167
Cdd:PRK13645 92 IGLVFQFPEYQLFQETIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNT 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 168 IFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDV-KVAAKTERILFMADGEIVS 225
Cdd:PRK13645 172 LVLDEPTGGLDPKGEEDFINLFERLNKEyKKRIIMVTHNMdQVLRIADEVIVMHEGKVIS 231
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
26-224 |
2.02e-17 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 78.97 E-value: 2.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 26 KNIDLEIYEGEFVSVMGPSGSGKS-----TLLYNISGMDQmSSGSVKIDSKELscmkeeALAKLRLTEIGFIFQQS---- 96
Cdd:PRK10418 20 HGVSLTLQRGRVLALVGGSGSGKSltcaaALGILPAGVRQ-TAGRVLLDGKPV------APCALRGRKIATIMQNPrsaf 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 97 NLLRNLNLFDNIILSAylakcESKKIVNKRALELMENMGISD---IASHYITEASGGQLQRVSICRALINNPNIIFADEP 173
Cdd:PRK10418 93 NPLHTMHTHARETCLA-----LGKPADDATLTAALEAVGLENaarVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEP 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446644341 174 TGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK10418 168 TTDLDVVAQARILDLLESIVQKrALGMLLVTHDMGVVARlADDVAVMSHGRIV 220
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
5-224 |
4.77e-17 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 80.06 E-value: 4.77e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscmKEEALAKL 84
Cdd:PRK11176 342 IEFRNVTFTYP---GKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDL---RDYTLASL 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RlTEIGFIFQQSNLLrNLNLFDNIilsAYLA--KCESKKIVN----KRALELMENM--GISDIASHYITEASGGQLQRVS 156
Cdd:PRK11176 416 R-NQVALVSQNVHLF-NDTIANNI---AYARteQYSREQIEEaarmAYAMDFINKMdnGLDTVIGENGVLLSGGQRQRIA 490
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKStEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:PRK11176 491 IARALLRDSPILILDEATSALDTES-ERAIQAALDELQKNRTSLVIAHRLSTIEKADEILVVEDGEIV 557
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
25-208 |
4.93e-17 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 78.85 E-value: 4.93e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRlTEIGFIFQqsNLLRNLN- 103
Cdd:PRK11308 31 LDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPEAQKLLR-QKIQIVFQ--NPYGSLNp 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 -------LFDNIILSAYLAKCESKKivnkRALELMENMGI-SDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTG 175
Cdd:PRK11308 108 rkkvgqiLEEPLLINTSLSAAERRE----KALAMMAKVGLrPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVS 183
|
170 180 190
....*....|....*....|....*....|....
gi 446644341 176 ALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKV 208
Cdd:PRK11308 184 ALDVSVQAQVLNLMMDLQQElGLSYVFISHDLSV 217
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
2-205 |
9.09e-17 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 76.68 E-value: 9.09e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNktYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAL 81
Cdd:PRK10247 5 SPLLQLQNVG--YLAGDAK---ILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKlrltEIGFIFQQSNLLRNlNLFDNIILSAYLAK--CESKKIVNKRA-LELMENMgisdiASHYITEASGGQLQRVSIC 158
Cdd:PRK10247 80 RQ----QVSYCAQTPTLFGD-TVYDNLIFPWQIRNqqPDPAIFLDDLErFALPDTI-----LTKNIAELSGGEKQRISLI 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446644341 159 RALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHD 205
Cdd:PRK10247 150 RNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVReQNIAVLWVTHD 197
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
4-226 |
1.02e-16 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 77.10 E-value: 1.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGntnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSkelSCMKEEALAK 83
Cdd:PRK13648 7 IIVFKNVSFQYQSDA---SFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNN---QAITDDNFEK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlTEIGFIFQQSNllrnlNLFDNIILSAYLA---------KCESKKIVNkralELMENMGISDIASHYITEASGGQLQR 154
Cdd:PRK13648 81 LR-KHIGIVFQNPD-----NQFVGSIVKYDVAfglenhavpYDEMHRRVS----EALKQVDMLERADYEPNALSGGQKQR 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 155 VSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:PRK13648 151 VAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSeHNITIISITHDLSEAMEADHVIVMNKGTVYKE 223
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
4-226 |
1.05e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 77.53 E-value: 1.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGM---DQMSSGSVKIDSKELScmkEEA 80
Cdd:PRK13640 5 IVEFKHVSFTYP---DSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLllpDDNPNSKITVDGITLT---AKT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLRlTEIGFIFQQ-SNLLRNLNLFDNIIL---SAYLAKCESKKIVNKraleLMENMGISDIASHYITEASGGQLQRVS 156
Cdd:PRK13640 79 VWDIR-EKVGIVFQNpDNQFVGATVGDDVAFgleNRAVPRPEMIKIVRD----VLADVGMLDYIDSEPANLSGGQKQRVA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:PRK13640 154 IAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLkKKNNLTVISITHDIDEANMADQVLVLDDGKLLAQ 224
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
23-224 |
1.33e-16 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 78.59 E-value: 1.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKST----LLYNISgmdqmSSGSVKIDSKELSCMKEEALAKLRlTEIGFIFQQSNL 98
Cdd:PRK15134 300 VVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLIN-----SQGEIWFDGQPLHNLNRRQLLPVR-HRIQVVFQDPNS 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 99 LRNLNLFDNIILSAYLA---KCESKKIVNKRALELMENMGISDIASH-YITEASGGQLQRVSICRALINNPNIIFADEPT 174
Cdd:PRK15134 374 SLNPRLNVLQIIEEGLRvhqPTLSAAQREQQVIAVMEEVGLDPETRHrYPAEFSGGQRQRIAIARALILKPSLIILDEPT 453
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446644341 175 GALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVA-AKTERILFMADGEIV 224
Cdd:PRK15134 454 SSLDKTVQAQILALLKSLqQKHQLAYLFISHDLHVVrALCHQVIVLRQGEVV 505
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
1-224 |
1.39e-16 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 76.75 E-value: 1.39e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKT--YSMDGNTNYHV--LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscm 76
Cdd:PRK15112 1 VETLLEVRNLSKTfrYRTGWFRRQTVeaVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPL--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 77 kEEALAKLRLTEIGFIFQQ-SNLL----RNLNLFD-NIILSAYLAKCESKKIVNkralELMENMGI-SDIASHYITEASG 149
Cdd:PRK15112 78 -HFGDYSYRSQRIRMIFQDpSTSLnprqRISQILDfPLRLNTDLEPEQREKQII----ETLRQVGLlPDHASYYPHMLAP 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 150 GQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNIN-RGGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK15112 153 GQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQeKQGISYIYVTQHLGMMKHiSDQVLVMHQGEVV 229
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
4-237 |
1.41e-16 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 78.71 E-value: 1.41e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSS--GSVKIDSKELSCmkeeal 81
Cdd:TIGR02633 1 LLEMKGIVKTFG-----GVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSPLKA------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKLRLTE---IGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVN---KRALELMENMGISDI-ASHYITEASGGQLQR 154
Cdd:TIGR02633 70 SNIRDTEragIVIIHQELTLVPELSVAENIFLGNEITLPGGRMAYNamyLRAKNLLRELQLDADnVTRPVGDYGGGQQQL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 155 VSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVSEIQLGKLR 233
Cdd:TIGR02633 150 VEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLnEVKAVCDTICVIRDGQHVATKDMSTMS 229
|
....
gi 446644341 234 NDDL 237
Cdd:TIGR02633 230 EDDI 233
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
28-224 |
1.70e-16 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 77.54 E-value: 1.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 28 IDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQ----MSSGSVKIDSKELSCMKEEALAKLRLTEIGFIFQ--QSNLLRN 101
Cdd:PRK15093 26 VSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKdnwrVTADRMRFDDIDLLRLSPRERRKLVGHNVSMIFQepQSCLDPS 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 102 LNLFDNIILS--AYLAKCESKKIVN---KRALELMENMGISD---IASHYITEASGGQLQRVSICRALINNPNIIFADEP 173
Cdd:PRK15093 106 ERVGRQLMQNipGWTYKGRWWQRFGwrkRRAIELLHRVGIKDhkdAMRSFPYELTEGECQKVMIAIALANQPRLLIADEP 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446644341 174 TGALNLKSTEEVMQILLNINR-GGTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK15093 186 TNAMEPTTQAQIFRLLTRLNQnNNTTILLISHDLQMLSQwADKINVLYCGQTV 238
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
21-204 |
1.90e-16 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 78.31 E-value: 1.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 21 NYHVL-KNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKElscmkeealaklrltEIGFIFQQSNL- 98
Cdd:COG4178 374 DGRPLlEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARPAGA---------------RVLFLPQRPYLp 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 99 ---LRNLNLFDNiilsaylakcESKKIVNKRALELMENMGISDIASHYITEA------SGGQLQRVSICRALINNPNIIF 169
Cdd:COG4178 439 lgtLREALLYPA----------TAEAFSDAELREALEAVGLGHLAERLDEEAdwdqvlSLGEQQRLAFARLLLHKPDWLF 508
|
170 180 190
....*....|....*....|....*....|....*
gi 446644341 170 ADEPTGALNLKSTEEVMQILLNiNRGGTTIMLVTH 204
Cdd:COG4178 509 LDEATSALDEENEAALYQLLRE-ELPGTTVISVGH 542
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
35-204 |
2.08e-16 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 78.38 E-value: 2.08e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 35 GEFVSVMGPSGSGKSTLLYNISGMDQMSS--GSVKIDSKELscmkeealAKLRLTEIGFIFQQSNLLRNLNLFDNIILSA 112
Cdd:PLN03211 94 GEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRKP--------TKQILKRTGFVTQDDILYPHLTVRETLVFCS 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 113 YL--AKCESKKIVNKRALELMENMGISD-----IASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEV 185
Cdd:PLN03211 166 LLrlPKSLTKQEKILVAESVISELGLTKcentiIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRL 245
|
170
....*....|....*....
gi 446644341 186 MQILLNINRGGTTIMLVTH 204
Cdd:PLN03211 246 VLTLGSLAQKGKTIVTSMH 264
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
4-212 |
2.52e-16 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 75.97 E-value: 2.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQM-----SSGSVKIDSKELSCMKE 78
Cdd:PRK14243 10 VLRTENLNVYYG-----SFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLipgfrVEGKVTFHGKNLYAPDV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 79 EALAKLRltEIGFIFQQSNLLRNlNLFDNIilsAYLAKCESKKI----VNKRAL-------ELMENMGISDIAshyiteA 147
Cdd:PRK14243 85 DPVEVRR--RIGMVFQKPNPFPK-SIYDNI---AYGARINGYKGdmdeLVERSLrqaalwdEVKDKLKQSGLS------L 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 148 SGGQLQRVSICRALINNPNIIFADEPTGALNLKST---EEVMQILlninRGGTTIMLVTHDVKVAAKT 212
Cdd:PRK14243 153 SGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTlriEELMHEL----KEQYTIIIVTHNMQQAARV 216
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
4-224 |
3.28e-16 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 77.59 E-value: 3.28e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTnYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSK----------EL 73
Cdd:PRK10261 12 VLAVENLNIAFMQEQQK-IAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMllrrrsrqviEL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 74 SCMKEEALAKLRLTEIGFIFQQSnlLRNLN-LF---DNIILSAYLAKCESKKIVNKRALELMENMGISD---IASHYITE 146
Cdd:PRK10261 91 SEQSAAQMRHVRGADMAMIFQEP--MTSLNpVFtvgEQIAESIRLHQGASREEAMVEAKRMLDQVRIPEaqtILSRYPHQ 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 147 ASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTT-IMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK10261 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMgVIFITHDMGVVAEiADRVLVMYQGEAV 248
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
4-204 |
3.37e-16 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 76.38 E-value: 3.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmKEEALAK 83
Cdd:PRK13537 7 PIDFRNVEKRYG-----DKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVP--SRARHAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRlteIGFIFQQSNLLRNLNLFDNI-ILSAYLAKceSKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALI 162
Cdd:PRK13537 80 QR---VGVVPQFDNLDPDFTVRENLlVFGRYFGL--SAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALV 154
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446644341 163 NNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTH 204
Cdd:PRK13537 155 NDPDVLVLDEPTTGLDPQARHLMWERLRSLLARGKTILLTTH 196
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
4-224 |
5.20e-16 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 76.04 E-value: 5.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKI-------------DS 70
Cdd:PRK13631 21 ILRVKNLYCVFDEKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyigdkknnheLI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 71 KELSCMKEEALAKLRLTeIGFIFQqsnlLRNLNLF-DNI---ILSAYLAKCESKKIVNKRALELMENMGI-SDIASHYIT 145
Cdd:PRK13631 101 TNPYSKKIKNFKELRRR-VSMVFQ----FPEYQLFkDTIekdIMFGPVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPF 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 146 EASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIV 224
Cdd:PRK13631 176 GLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMeHVLEVADEVIVMDKGKIL 255
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
5-205 |
9.04e-16 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 72.10 E-value: 9.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKelscmkeealakl 84
Cdd:cd03221 1 IELENLSKTYG-----GKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGST------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rlTEIGfifqqsnllrnlnlfdniilsaylakceskkivnkralelmenmgisdiashYITEASGGQLQRVSICRALINN 164
Cdd:cd03221 63 --VKIG----------------------------------------------------YFEQLSGGEKMRLALAKLLLEN 88
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILLNINRggtTIMLVTHD 205
Cdd:cd03221 89 PNLLLLDEPTNHLDLESIEALEEALKEYPG---TVILVSHD 126
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
2-224 |
1.99e-15 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 75.10 E-value: 1.99e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNKTYsmDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKelscmkeeal 81
Cdd:COG0488 313 KKVLELEGLSKSY--GDKT---LLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGET---------- 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 aklrlTEIGFIFQQSNLLR-NLNLFDNIilSAYLAKCESKKIVNkraleLMENMGIS-DIASHYITEASGGQLQRVSICR 159
Cdd:COG0488 378 -----VKIGYFDQHQEELDpDKTVLDEL--RDGAPGGTEQEVRG-----YLGRFLFSgDDAFKPVGVLSGGEKARLALAK 445
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 160 ALINNPNIIFADEPTGALNLKSTEEVMQILLNINrGgtTIMLVTHDV----KVAaktERILFMADGEIV 224
Cdd:COG0488 446 LLLSPPNVLLLDEPTNHLDIETLEALEEALDDFP-G--TVLLVSHDRyfldRVA---TRILEFEDGGVR 508
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
24-224 |
2.21e-15 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 75.24 E-value: 2.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTL------LYNISgmdqmsSGSVKIDSKELScmkEEALAKLRlTEIGfIFQQSN 97
Cdd:COG5265 373 ILKGVSFEVPAGKTVAIVGPSGAGKSTLarllfrFYDVT------SGRILIDGQDIR---DVTQASLR-AAIG-IVPQDT 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 98 LLRNLNLFDNIilsAYLAKCESKKIVNkRALELMEnmgISD-IAS---HYITEA-------SGGQLQRVSICRALINNPN 166
Cdd:COG5265 442 VLFNDTIAYNI---AYGRPDASEEEVE-AAARAAQ---IHDfIESlpdGYDTRVgerglklSGGEKQRVAIARTLLKNPP 514
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 167 IIFADEPTGALNLKSTEEVMQILLNINRGGTTIMlVTHDVKVAAKTERILFMADGEIV 224
Cdd:COG5265 515 ILIFDEATSALDSRTERAIQAALREVARGRTTLV-IAHRLSTIVDADEILVLEAGRIV 571
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
24-225 |
2.87e-15 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 74.72 E-value: 2.87e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKelscmkeealaklrlTEIGFIFQQSNLLRNLN 103
Cdd:COG0488 13 LLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKG---------------LRIGYLPQEPPLDDDLT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNII--------LSAYLAKCESK------------KIVNK-----------RALELMENMGISDiASHY--ITEASGG 150
Cdd:COG0488 78 VLDTVLdgdaelraLEAELEELEAKlaepdedlerlaELQEEfealggweaeaRAEEILSGLGFPE-EDLDrpVSELSGG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 151 QLQRVSICRALINNPNIIFADEPTGALNLKSTE--EvmQILLniNRGGtTIMLVTHDV----KVAaktERILFMADGEIV 224
Cdd:COG0488 157 WRRRVALARALLSEPDLLLLDEPTNHLDLESIEwlE--EFLK--NYPG-TVLVVSHDRyfldRVA---TRILELDRGKLT 228
|
.
gi 446644341 225 S 225
Cdd:COG0488 229 L 229
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
24-226 |
3.11e-15 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 73.32 E-value: 3.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMS--------SGSVKIDSKELSCMKEEALAKLRL-----TEIG 90
Cdd:PRK13547 16 ILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAAIDAPRLARLRAvlpqaAQPA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 91 FIFQQSNLLRnLNLFDNIILSAYLAKcESKKIVNkRALELmenMGISDIASHYITEASGGQLQRVSICRAL--------- 161
Cdd:PRK13547 96 FAFSAREIVL-LGRYPHARRAGALTH-RDGEIAW-QALAL---AGATALVGRDVTTLSGGELARVQFARVLaqlwpphda 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 162 INNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK13547 170 AQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDwNLGVLAIVHDPNLAARhADRIAMLADGAIVAH 236
|
|
| sufC |
TIGR01978 |
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ... |
23-226 |
4.85e-15 |
|
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 72.29 E-value: 4.85e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMD--QMSSGSVKIDSKELSCMKEEALAKLRL-------TEIG--- 90
Cdd:TIGR01978 14 EILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGHPsyEVTSGTILFKGQDLLELEPDERARAGLflafqypEEIPgvs 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 91 ---FIFQQSNLLRNLNLFDNIILSAYLAKCESKkivnKRALELMENMgisdiASHYITEA-SGGQLQRVSICRALINNPN 166
Cdd:TIGR01978 94 nleFLRSALNARRSARGEEPLDLLDFEKLLKEK----LALLDMDEEF-----LNRSVNEGfSGGEKKRNEILQMALLEPK 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 167 IIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKV--AAKTERILFMADGEIVSE 226
Cdd:TIGR01978 165 LAILDEIDSGLDIDALKIVAEGINRLREPDRSFLIITHYQRLlnYIKPDYVHVLLDGRIVKS 226
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
24-225 |
5.18e-15 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 71.29 E-value: 5.18e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKeeaLAKLRlTEIGFIFQQSNLL---- 99
Cdd:cd03369 23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIP---LEDLR-SSLTIIPQDPTLFsgti 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 100 -RNLNLFDNiilsaYLAKceskkivnkralELMENMGISDIASHYiteaSGGQLQRVSICRALINNPNIIFADEPTGALN 178
Cdd:cd03369 99 rSNLDPFDE-----YSDE------------EIYGALRVSEGGLNL----SQGQRQLLCLARALLKRPRVLVLDEATASID 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446644341 179 LkSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIVS 225
Cdd:cd03369 158 Y-ATDALIQKTIREEFTNSTILTIAHRLRTIIDYDKILVMDAGEVKE 203
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
31-225 |
5.94e-15 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 71.89 E-value: 5.94e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 31 EIYEGEFVSVMGPSGSGKSTLLYNISGMdQMSSGSVKIDSKELSCMKEEALAKLRlteiGFIFQQSNLLRNLNLFDNIIL 110
Cdd:PRK03695 18 EVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAELARHR----AYLSQQQTPPFAMPVFQYLTL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 111 S--AYLAKCESKKIVNkralELMENMGISDIASHYITEASGGQLQRVSICRALI-----NNPN--IIFADEPTGALNLKS 181
Cdd:PRK03695 93 HqpDKTRTEAVASALN----EVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLqvwpdINPAgqLLLLDEPMNSLDVAQ 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446644341 182 TEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVS 225
Cdd:PRK03695 169 QAALDRLLSELCQQGIAVVMSSHDLnHTLRHADRVWLLKQGKLLA 213
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-226 |
6.75e-15 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 71.83 E-value: 6.75e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkEEA 80
Cdd:PRK11614 2 EKVMLSFDKVSAHYG-----KIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDIT---DWQ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLRLTEIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRALELMENMgiSDIASHYITEASGGQLQRVSICRA 160
Cdd:PRK11614 74 TAKIMREAVAIVPEGRRVFSRMTVEENLAMGGFFAERDQFQERIKWVYELFPRL--HERRIQRAGTMSGGEQQMLAIGRA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 161 LINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK11614 152 LMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKlADRGYVLENGHVVLE 218
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
5-204 |
1.05e-14 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 72.56 E-value: 1.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSkelscMKEEALAKL 84
Cdd:PRK13536 42 IDLAGVSKSYG-----DKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLG-----VPVPARARL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 RLTEIGFIFQQSNLLRNLNLFDN-IILSAYLAkceskkiVNKRALE-----LMENMGISDIASHYITEASGGQLQRVSIC 158
Cdd:PRK13536 112 ARARIGVVPQFDNLDLEFTVRENlLVFGRYFG-------MSTREIEavipsLLEFARLESKADARVSDLSGGMKRRLTLA 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446644341 159 RALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTH 204
Cdd:PRK13536 185 RALINDPQLLILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTH 230
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
14-205 |
1.47e-14 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 72.66 E-value: 1.47e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 14 YSMDG-----NTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGsvkidskelscmkeEALAKLRLTe 88
Cdd:TIGR03719 5 YTMNRvskvvPPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNG--------------EARPQPGIK- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 89 IGFIFQQSNLLRNLNLFDNIILSaylakCESKKIVNKRALELMENMGISD------------------------------ 138
Cdd:TIGR03719 70 VGYLPQEPQLDPTKTVRENVEEG-----VAEIKDALDRFNEISAKYAEPDadfdklaaeqaelqeiidaadawdldsqle 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 139 IASHY---------ITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILlnINRGGTTIMlVTHD 205
Cdd:TIGR03719 145 IAMDAlrcppwdadVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHL--QEYPGTVVA-VTHD 217
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
23-229 |
1.59e-14 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 70.37 E-value: 1.59e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGmdqmssgsvkidskELSCMKEEALAKLRLTEIGfifqqsnllRNL 102
Cdd:COG2401 44 YVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAG--------------ALKGTPVAGCVDVPDNQFG---------REA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 103 NLFDNIilsaylakceSKKIVNKRALELMENMGISDIAShYIT---EASGGQLQRVSICRALINNPNIIFADEPTGALNL 179
Cdd:COG2401 101 SLIDAI----------GRKGDFKDAVELLNAVGLSDAVL-WLRrfkELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDR 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446644341 180 KSTEEVMQILLNINR-GGTTIMLVTH--DVKVAAKTERILFMADGEIVSEIQL 229
Cdd:COG2401 170 QTAKRVARNLQKLARrAGITLVVATHhyDVIDDLQPDLLIFVGYGGVPEEKRR 222
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
4-226 |
1.60e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 71.37 E-value: 1.60e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgnTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkEEALAK 83
Cdd:PRK13652 3 LIETRDLCYSYS----GSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPIT---KENIRE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 LRLTeIGFIFQQSnllrnlnlfDNIILSAYLAK------CE---SKKIVNKRALELMENMGISDIASHYITEASGGQLQR 154
Cdd:PRK13652 76 VRKF-VGLVFQNP---------DDQIFSPTVEQdiafgpINlglDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKR 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 155 VSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVK-VAAKTERILFMADGEIVSE 226
Cdd:PRK13652 146 VAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLpETYGMTVIFSTHQLDlVPEMADYIYVMDKGRIVAY 219
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
25-225 |
1.83e-14 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 70.64 E-value: 1.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQmSSGSVKIDSKELSCMKEEALAKLRlteiGFIFQQSNLLRNLNL 104
Cdd:COG4138 12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDWSAAELARHR----AYLSQQQSPPFAMPV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 105 FDniILSAYLAKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALI-----NNPN--IIFADEPTGAL 177
Cdd:COG4138 87 FQ--YLALHQPAGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptINPEgqLLLLDEPMNSL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 178 NLksteeVMQILLN--INR----GGTTIMlVTHDVKVAAK-TERILFMADGEIVS 225
Cdd:COG4138 165 DV-----AQQAALDrlLRElcqqGITVVM-SSHDLNHTLRhADRVWLLKQGKLVA 213
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
11-226 |
3.77e-14 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 71.93 E-value: 3.77e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 11 NKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGmdqmssgsvkidskELSCMkEEALAKLRLTeIG 90
Cdd:PLN03232 619 NGYFSWDSKTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLG--------------ELSHA-ETSSVVIRGS-VA 682
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 91 FIFQQSNLLrNLNLFDNIILSAYLAKCESKKIVNKRALE----LMENMGISDIASHYITeASGGQLQRVSICRALINNPN 166
Cdd:PLN03232 683 YVPQVSWIF-NATVRENILFGSDFESERYWRAIDVTALQhdldLLPGRDLTEIGERGVN-ISGGQKQRVSMARAVYSNSD 760
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 167 IIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:PLN03232 761 IYIFDDPLSALDAHVAHQVFDSCMKDELKGKTRVLVTNQLHFLPLMDRIILVSEGMIKEE 820
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
5-219 |
4.34e-14 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 68.67 E-value: 4.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVnkTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEAlakl 84
Cdd:cd03231 1 LEADEL--TCERDGRA---LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSI---- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rLTEIGFIFQQSNLLRNLNLFDNiiLSAYLAKCESKKIvnKRALELMENMGISDIASHYIteaSGGQLQRVSICRALINN 164
Cdd:cd03231 72 -ARGLLYLGHAPGIKTTLSVLEN--LRFWHADHSDEQV--EEALARVGLNGFEDRPVAQL---SAGQQRRVALARLLLSG 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 165 PNIIFADEPTGALNLKSTEEVMQILL-NINRGGTTIMLVTHDVKVAAKTERILFMA 219
Cdd:cd03231 144 RPLWILDEPTTALDKAGVARFAEAMAgHCARGGMVVLTTHQDLGLSEAGARELDLG 199
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
11-226 |
1.69e-13 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 69.77 E-value: 1.69e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 11 NKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISG-MDQMSSGSVKIDSKelscmkeeaLAklRLTEI 89
Cdd:PLN03130 619 NGYFSWDSKAERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGeLPPRSDASVVIRGT---------VA--YVPQV 687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 90 GFIFqqsnllrNLNLFDNIILSAYLAKCESKKIVN----KRALELMENMGISDIASHYITeASGGQLQRVSICRALINNP 165
Cdd:PLN03130 688 SWIF-------NATVRDNILFGSPFDPERYERAIDvtalQHDLDLLPGGDLTEIGERGVN-ISGGQKQRVSMARAVYSNS 759
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 166 NIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIVSE 226
Cdd:PLN03130 760 DVYIFDDPLSALDAHVGRQVFDKCIKDELRGKTRVLVTNQLHFLSQVDRIILVHEGMIKEE 820
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
18-224 |
1.94e-13 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 69.35 E-value: 1.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 18 GNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNI-----SGMDQMSSGSVKIDSKELSCMKEEALAKLRLTEIGFI 92
Cdd:PRK15134 18 QQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSIlrllpSPPVVYPSGDIRFHGESLLHASEQTLRGVRGNKIAMI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 93 FQQSnlLRNLNLFDNI------ILSayLAKCESKKIVNKRALELMENMGISDIASH---YITEASGGQLQRVSICRALIN 163
Cdd:PRK15134 98 FQEP--MVSLNPLHTLekqlyeVLS--LHRGMRREAARGEILNCLDRVGIRQAAKRltdYPHQLSGGERQRVMIAMALLT 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 164 NPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIV 224
Cdd:PRK15134 174 RPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITHNLSIVRKlADRVAVMQNGRCV 236
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-225 |
2.02e-13 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 69.19 E-value: 2.02e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSS--GSVKIDSKELscmke 78
Cdd:PRK13549 2 MEYLLEMKNITKTFG-----GVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGTyeGEIIFEGEEL----- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 79 eALAKLRLTE---IGFIFQQSNLLRNLNLFDNIILSAYLAKcesKKIVN-----KRALELMENMGIsDIASHY-ITEASG 149
Cdd:PRK13549 72 -QASNIRDTEragIAIIHQELALVKELSVLENIFLGNEITP---GGIMDydamyLRAQKLLAQLKL-DINPATpVGNLGL 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 150 GQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVS 225
Cdd:PRK13549 147 GQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLnEVKAISDTICVIRDGRHIG 223
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
24-216 |
2.40e-13 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 67.45 E-value: 2.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDskelscmkeealAKLRlteIGFIFQQSNLLRNLN 103
Cdd:PRK09544 19 VLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRN------------GKLR---IGYVPQKLYLDTTLP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LfdniilsaylakceskkiVNKRALELMENMGISDI--------ASHYI----TEASGGQLQRVSICRALINNPNIIFAD 171
Cdd:PRK09544 84 L------------------TVNRFLRLRPGTKKEDIlpalkrvqAGHLIdapmQKLSGGETQRVLLARALLNRPQLLVLD 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446644341 172 EPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVK-VAAKTERIL 216
Cdd:PRK09544 146 EPTQGVDVNGQVALYDLIDQLRRElDCAVLMVSHDLHlVMAKTDEVL 192
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
25-223 |
2.52e-13 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 69.20 E-value: 2.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISG-MDQMSsGSVKIDSkelscmkeealaklrltEIGFIFQQSnLLRNLN 103
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAeMDKVE-GHVHMKG-----------------SVAYVPQQA-WIQNDS 714
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVNKRAL----ELMENMGISDIASHYITeASGGQLQRVSICRALINNPNIIFADEPTGALNL 179
Cdd:TIGR00957 715 LRENILFGKALNEKYYQQVLEACALlpdlEILPSGDRTEIGEKGVN-LSGGQKQRVSLARAVYSNADIYLFDDPLSAVDA 793
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446644341 180 KSTEEVMQILLNIN--RGGTTIMLVTHDVKVAAKTERILFMADGEI 223
Cdd:TIGR00957 794 HVGKHIFEHVIGPEgvLKNKTRILVTHGISYLPQVDVIIVMSGGKI 839
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
24-224 |
3.70e-13 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 68.59 E-value: 3.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrlteiGF-IFQQSNLLRNL 102
Cdd:PRK10790 356 VLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQ------GVaMVQQDPVVLAD 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 103 NLFDNIILSAYLAKCESKKIVNKRAL-ELMENM--GISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGalNL 179
Cdd:PRK10790 430 TFLANVTLGRDISEEQVWQALETVQLaELARSLpdGLYTPLGEQGNNLSVGQKQLLALARVLVQTPQILILDEATA--NI 507
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446644341 180 KS-TEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:PRK10790 508 DSgTEQAIQQALAAVREHTTLVVIAHRLSTIVEADTILVLHRGQAV 553
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-71 |
4.05e-13 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 66.64 E-value: 4.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSMDGNTNY-----------------HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSS 63
Cdd:COG1134 1 MSSMIEVENVSKSYRLYHEPSRslkelllrrrrtrreefWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTS 80
|
....*...
gi 446644341 64 GSVKIDSK 71
Cdd:COG1134 81 GRVEVNGR 88
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
28-223 |
7.32e-13 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 68.12 E-value: 7.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 28 IDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscmkEEALAKLRLTeIGFIFQQSNLLRNLNLFDN 107
Cdd:TIGR01257 949 LNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDI----ETNLDAVRQS-LGMCPQHNILFHHLTVAEH 1023
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 108 IILSAYLaKCESKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQ 187
Cdd:TIGR01257 1024 ILFYAQL-KGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWD 1102
|
170 180 190
....*....|....*....|....*....|....*.
gi 446644341 188 ILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEI 223
Cdd:TIGR01257 1103 LLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRL 1138
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
19-221 |
7.50e-13 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 65.34 E-value: 7.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 19 NTNYHV---------LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMS--SGSVKIDSKELscmkEEALAKlrlt 87
Cdd:cd03232 8 NLNYTVpvkggkrqlLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGviTGEILINGRPL----DKNFQR---- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 88 EIGFIFQQSNLLRNLNLFDNIILSAYLakceskkivnkRALelmenmgisdiashyiteaSGGQLQRVSICRALINNPNI 167
Cdd:cd03232 80 STGYVEQQDVHSPNLTVREALRFSALL-----------RGL-------------------SVEQRKRLTIGVELAAKPSI 129
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 168 IFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTH--DVKVAAKTERILFMADG 221
Cdd:cd03232 130 LFLDEPTSGLDSQAAYNIVRFLKKLADSGQAILCTIHqpSASIFEKFDRLLLLKRG 185
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
22-224 |
1.35e-12 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 64.86 E-value: 1.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 22 YHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmkeealaklrLTEIGFIFQQsnllrN 101
Cdd:cd03220 35 FWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVSS-----------LLGLGGGFNP-----E 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 102 LNLFDNIILSAYLAKCeSKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKS 181
Cdd:cd03220 99 LTGRENIYLNGRLLGL-SRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAF 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446644341 182 TEEVMQILLNINRGGTTIMLVTHDVKVAAKT-ERILFMADGEIV 224
Cdd:cd03220 178 QEKCQRRLRELLKQGKTVILVSHDPSSIKRLcDRALVLEKGKIR 221
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
31-231 |
2.26e-12 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 64.74 E-value: 2.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 31 EIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRLTEIGFIFQQSNLLRNLNLFDNiil 110
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKPQYIKADYEGTVRDLLSSITKDFYTHPYFKT--- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 111 saylakceskkivnkralELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALN----LKSTEEVM 186
Cdd:cd03237 98 ------------------EIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDveqrLMASKVIR 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446644341 187 QILLNINRggtTIMLVTHDVKVAAkterilFMADGEIVSEIQLGK 231
Cdd:cd03237 160 RFAENNEK---TAFVVEHDIIMID------YLADRLIVFEGEPSV 195
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-237 |
2.77e-12 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 65.80 E-value: 2.77e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCM---- 76
Cdd:PRK10762 1 MQALLQLKGIDKAFP-----GVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNgpks 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 77 KEEAlaklrltEIGFIFQQSNLLRNLNLFDNIILS----AYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQL 152
Cdd:PRK10762 76 SQEA-------GIGIIHQELNLIPQLTIAENIFLGrefvNRFGRIDWKKM-YAEADKLLARLNLRFSSDKLVGELSIGEQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 153 QRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVK-VAAKTERILFMADGEIVSEIQLGK 231
Cdd:PRK10762 148 QMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRLKeIFEICDDVTVFRDGQFIAEREVAD 227
|
....*.
gi 446644341 232 LRNDDL 237
Cdd:PRK10762 228 LTEDSL 233
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
12-224 |
2.84e-12 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 66.34 E-value: 2.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 12 KTYSMDGNTNYHV-----LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVkidskelscMKEEALAklrl 86
Cdd:PTZ00243 658 KTPKMKTDDFFELepkvlLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV---------WAERSIA---- 724
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 87 teigFIFQQSNLLrNLNLFDNIIL-----SAYLAKceskkIVNKRALElmenmgiSDIAS------HYITEA----SGGQ 151
Cdd:PTZ00243 725 ----YVPQQAWIM-NATVRGNILFfdeedAARLAD-----AVRVSQLE-------ADLAQlgggleTEIGEKgvnlSGGQ 787
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 152 LQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:PTZ00243 788 KARVSLARAVYANRDVYLLDDPLSALDAHVGERVVEECFLGALAGKTRVLATHQVHVVPRADYVVALGDGRVE 860
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
24-204 |
4.15e-12 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 63.35 E-value: 4.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKElscmKEEALAKLRLTEIGfifQQSNLLRNLN 103
Cdd:PRK13539 17 LFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGD----IDDPDVAEACHYLG---HRNAMKPALT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVnkRALELMENMGISDIASHYIteaSGGQLQRVSICRALINNPNIIFADEPTGALNLKSTE 183
Cdd:PRK13539 90 VAENLEFWAAFLGGEELDIA--AALEAVGLAPLAHLPFGYL---SAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVA 164
|
170 180
....*....|....*....|....
gi 446644341 184 ---EVMQILLniNRGGTTIMlVTH 204
Cdd:PRK13539 165 lfaELIRAHL--AQGGIVIA-ATH 185
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
24-205 |
7.55e-12 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 64.88 E-value: 7.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDskelscmkeealAKLRLTeigfIFQQSNLlRNLN 103
Cdd:PLN03073 524 LFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRS------------AKVRMA----VFSQHHV-DGLD 586
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILsaYLAKCeSKKIVNKRALELMENMGIS-DIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKST 182
Cdd:PLN03073 587 LSSNPLL--YMMRC-FPGVPEQKLRAHLGSFGVTgNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAV 663
|
170 180
....*....|....*....|...
gi 446644341 183 EEVMQILLnINRGGttIMLVTHD 205
Cdd:PLN03073 664 EALIQGLV-LFQGG--VLMVSHD 683
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
24-204 |
1.49e-11 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 61.02 E-value: 1.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKidskelscmkeealaKLRLTEIGFIFQQSnLLRNLN 103
Cdd:cd03223 16 LLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIG---------------MPEGEDLLFLPQRP-YLPLGT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYlakceskkivnkRALelmenmgisdiashyiteaSGGQLQRVSICRALINNPNIIFADEPTGALNLKSTE 183
Cdd:cd03223 80 LREQLIYPWD------------DVL-------------------SGGEQQRLAFARLLLHKPKFVFLDEATSALDEESED 128
|
170 180
....*....|....*....|.
gi 446644341 184 EVMQILlniNRGGTTIMLVTH 204
Cdd:cd03223 129 RLYQLL---KELGITVISVGH 146
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
27-216 |
2.00e-11 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 61.36 E-value: 2.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 27 NIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLRlteigFIFQQSNLLRNLNLFD 106
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEYHQDLL-----YLGHQPGIKTELTALE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 107 NIILSAYLAKCESKKIVNkRALELMENMGISDIASHYIteaSGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVM 186
Cdd:PRK13538 94 NLRFYQRLHGPGDDEALW-EALAQVGLAGFEDVPVRQL---SAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVARLE 169
|
170 180 190
....*....|....*....|....*....|.
gi 446644341 187 QILL-NINRGGTTIMLVTHDVKVAAKTERIL 216
Cdd:PRK13538 170 ALLAqHAEQGGMVILTTHQDLPVASDKVRKL 200
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
26-223 |
2.85e-11 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 62.76 E-value: 2.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 26 KNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKeealAKLRLtEIGFIF-----QQSNLLR 100
Cdd:PRK15439 280 RNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALS----TAQRL-ARGLVYlpedrQSSGLYL 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 NLNLFDNII------LSAYLAKCESKKIVNK--RALelmeNMGISDiASHYITEASGGQLQRVSICRALINNPNIIFADE 172
Cdd:PRK15439 355 DAPLAWNVCalthnrRGFWIKPARENAVLERyrRAL----NIKFNH-AEQAARTLSGGNQQKVLIAKCLEASPQLLIVDE 429
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446644341 173 PTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEI 223
Cdd:PRK15439 430 PTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDLeEIEQMADRVLVMHQGEI 481
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
26-247 |
3.99e-11 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 62.49 E-value: 3.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 26 KNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKE-EALAKlrltEIGFIFQ---QSNLLRN 101
Cdd:PRK09700 280 RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPlDAVKK----GMAYITEsrrDNGFFPN 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 102 LNLFDNIILSAYL-------------AKCESKKIVNKRALELMENMGISdiasHYITEASGGQLQRVSICRALINNPNII 168
Cdd:PRK09700 356 FSIAQNMAISRSLkdggykgamglfhEVDEQRTAENQRELLALKCHSVN----QNITELSGGNQQKVLISKWLCCCPEVI 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 169 FADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVSEiqlgkLRNDDlKAREEKLLNW 247
Cdd:PRK09700 432 IFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELpEIITVCDRIAVFCEGRLTQI-----LTNRD-DMSEEEIMAW 505
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
7-206 |
6.69e-11 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 61.05 E-value: 6.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 7 VKQVNKTYSmDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIdskelscMKEEALAKLRL 86
Cdd:PRK15056 9 VNDVTVTWR-NGHT---ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISI-------LGQPTRQALQK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 87 TEIGFIFQQSNLLRNLNLF--DNIILSAY-------LAKCESKKIVNkralELMENMGISDIASHYITEASGGQLQRVSI 157
Cdd:PRK15056 78 NLVAYVPQSEEVDWSFPVLveDVVMMGRYghmgwlrRAKKRDRQIVT----AALARVDMVEFRHRQIGELSGGQKKRVFL 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446644341 158 CRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV 206
Cdd:PRK15056 154 ARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNL 202
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
24-232 |
9.02e-11 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 60.41 E-value: 9.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAkLRlTEIGFIFQQSNL----- 98
Cdd:PRK13638 16 VLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGLLA-LR-QQVATVFQDPEQqifyt 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 99 ---------LRNLNLfdniilsaylAKCESKKIVNKrALELMEnmgisdiASHY----ITEASGGQLQRVSICRALINNP 165
Cdd:PRK13638 94 didsdiafsLRNLGV----------PEAEITRRVDE-ALTLVD-------AQHFrhqpIQCLSHGQKKRVAIAGALVLQA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 166 NIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAK-TERILFMADGEIVSEIQLGKL 232
Cdd:PRK13638 156 RYLLLDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEiSDAVYVLRQGQILTHGAPGEV 223
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
11-226 |
1.16e-10 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 60.19 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 11 NKTYSMDGNTNYHVLKnidLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKlrltEIG 90
Cdd:PRK10575 16 NVSFRVPGRTLLHPLS---LTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFAR----KVA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 91 FIFQQSNLLRNLNLFDNIILSAY-----LAKCESKKivNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNP 165
Cdd:PRK10575 89 YLPQQLPAAEGMTVRELVAIGRYpwhgaLGRFGAAD--REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDS 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 166 NIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAK-TERILFMADGEIVSE 226
Cdd:PRK10575 167 RCLLLDEPTSALDIAHQVDVLALVHRLSQErGLTVIAVLHDINMAARyCDYLVALRGGEMIAQ 229
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
25-245 |
1.29e-10 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 60.79 E-value: 1.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMK-EEALAklrlTEIGFIFQQ---SNLLR 100
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSpQDGLA----NGIVYISEDrkrDGLVL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 NLNLFDNIILSA--YLakceSKKIVNKRALElmENMGISDIASHY----------ITEASGGQLQRVSICRALINNPNII 168
Cdd:PRK10762 344 GMSVKENMSLTAlrYF----SRAGGSLKHAD--EQQAVSDFIRLFniktpsmeqaIGLLSGGNQQKVAIARGLMTRPKVL 417
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 169 FADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVSEIQLGklrnddlKAREEKLL 245
Cdd:PRK10762 418 ILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMpEVLGMSDRILVMHEGRISGEFTRE-------QATQEKLM 488
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
24-222 |
2.20e-10 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 59.49 E-value: 2.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKelscmkeealaklrlteIGFIFQQSNLLRNlN 103
Cdd:cd03291 52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR-----------------ISFSSQFSWIMPG-T 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVnkRALELMENmgISDIASHYIT-------EASGGQLQRVSICRALINNPNIIFADEPTGA 176
Cdd:cd03291 114 IKENIIFGVSYDEYRYKSVV--KACQLEED--ITKFPEKDNTvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFGY 189
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446644341 177 LNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGE 222
Cdd:cd03291 190 LDVFTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGS 235
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
14-205 |
2.95e-10 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 59.75 E-value: 2.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 14 YSMDGNTNYH-----VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGsvkidskelscmkeEALAKLRLTe 88
Cdd:PRK11819 7 YTMNRVSKVVppkkqILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEG--------------EARPAPGIK- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 89 IGFIFQQSNLLRNLNLFDNII-----LSAYLAKCEskKIVNKRAL------ELMENMG-ISDIASHY------------- 143
Cdd:PRK11819 72 VGYLPQEPQLDPEKTVRENVEegvaeVKAALDRFN--EIYAAYAEpdadfdALAAEQGeLQEIIDAAdawdldsqleiam 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 144 -----------ITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINrGgtTIMLVTHD 205
Cdd:PRK11819 150 dalrcppwdakVTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLEQFLHDYP-G--TVVAVTHD 219
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
24-221 |
3.75e-10 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 59.92 E-value: 3.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKelscmkeealaklrlteIGFIFQQSNLLRNlN 103
Cdd:TIGR01271 441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR-----------------ISFSPQTSWIMPG-T 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVNKRALE----LMENMGISDIASHYITeASGGQLQRVSICRALINNPNIIFADEPTGALNL 179
Cdd:TIGR01271 503 IKDNIIFGLSYDEYRYTSVIKACQLEediaLFPEKDKTVLGEGGIT-LSGGQRARISLARAVYKDADLYLLDSPFTHLDV 581
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446644341 180 KSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADG 221
Cdd:TIGR01271 582 VTEKEIFESCLCKLMSNKTRILVTSKLEHLKKADKILLLHEG 623
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
24-224 |
4.76e-10 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 59.34 E-value: 4.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALaKLRLTEIG---FIFQQSnllr 100
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSW-RSRLAVVSqtpFLFSDT---- 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 nlnLFDNIILSAYLAKCESKKIVNKRAlELMENmgISDIASHYITEA-------SGGQLQRVSICRALINNPNIIFADEP 173
Cdd:PRK10789 405 ---VANNIALGRPDATQQEIEHVARLA-SVHDD--ILRLPQGYDTEVgergvmlSGGQKQRISIARALLLNAEILILDDA 478
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446644341 174 TGALNLKsTEEvmQILLNINRGGT--TIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:PRK10789 479 LSAVDGR-TEH--QILHNLRQWGEgrTVIISAHRLSALTEASEILVMQHGHIA 528
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
25-235 |
4.98e-10 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 58.97 E-value: 4.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMK-EEALAklrlTEIGFIFQQSNLLRNLN 103
Cdd:PRK10982 14 LDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSsKEALE----NGISMVHQELNLVLQRS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAK---CESKKIVNKrALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLK 180
Cdd:PRK10982 90 VMDNMWLGRYPTKgmfVDQDKMYRD-TKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEK 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 181 STEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVSEIQLGKLRND 235
Cdd:PRK10982 169 EVNHLFTIIRKLKERGCGIVYISHKMeEIFQLCDEITILRDGQWIATQPLAGLTMD 224
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
29-202 |
7.87e-10 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 58.49 E-value: 7.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 29 DLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALAKLrlteIGFIFQQSNL-LRNLNLFDN 107
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEQLQKL----VSDEWQRNNTdMLSPGEDDT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 108 IILSAYLAKCESKKivNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQ 187
Cdd:PRK10938 99 GRTTAEIIQDEVKD--PARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAE 176
|
170
....*....|....*
gi 446644341 188 ILLNINRGGTTIMLV 202
Cdd:PRK10938 177 LLASLHQSGITLVLV 191
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
119-240 |
9.52e-10 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 58.21 E-value: 9.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 119 SKKIVNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTT 198
Cdd:NF000106 117 SRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGAT 196
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 446644341 199 IMLVTHDVKVAAKTERILFMAD-GEIVSEiqlGKLrnDDLKAR 240
Cdd:NF000106 197 VLLTTQYMEEAEQLAHELTVIDrGRVIAD---GKV--DELKTK 234
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
40-220 |
1.12e-09 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 57.58 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 40 VMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELS-CMKEEALA--KLRlteIGFIFQQSNLL------RNLNlfdniil 110
Cdd:PRK11144 29 IFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFdAEKGICLPpeKRR---IGYVFQDARLFphykvrGNLR------- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 111 saYLAKCESKKIVNKraleLMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQIL- 189
Cdd:PRK11144 99 --YGMAKSMVAQFDK----IVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLe 172
|
170 180 190
....*....|....*....|....*....|....*.
gi 446644341 190 -----LNInrggtTIMLVTHDVkvaaktERILFMAD 220
Cdd:PRK11144 173 rlareINI-----PILYVSHSL------DEILRLAD 197
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
4-221 |
1.91e-09 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 57.72 E-value: 1.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELscmkeealak 83
Cdd:TIGR01257 1937 ILRLNELTKVYS---GTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSI---------- 2003
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 84 lrLTEIGFIFQQSNLLRNLNLFDNII-------LSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVS 156
Cdd:TIGR01257 2004 --LTNISDVHQNMGYCPQFDAIDDLLtgrehlyLYARLRGVPAEEI-EKVANWSIQSLGLSLYADRLAGTYSGGNKRKLS 2080
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADG 221
Cdd:TIGR01257 2081 TAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMeECEALCTRLAIMVKG 2146
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
34-244 |
2.50e-09 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 56.22 E-value: 2.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 34 EGEFVSVMGPSGSGKSTLLYNISGMDQMSSGsvKIDSKElscMKEEALAKLRLTEIGFIFQQsnlLRNLNLfDNIILSAY 113
Cdd:cd03236 25 EGQVLGLVGPNGIGKSTALKILAGKLKPNLG--KFDDPP---DWDEILDEFRGSELQNYFTK---LLEGDV-KVIVKPQY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 114 L------AKCESKKIVNKR----AL-ELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKST 182
Cdd:cd03236 96 VdlipkaVKGKVGELLKKKdergKLdELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQR 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 183 EEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGE-----IVS----------EIQLGKLRNDDLKAREEKL 244
Cdd:cd03236 176 LNAARLIRELAEDDNYVLVVEHDLAVLDYLSDYIHCLYGEpgaygVVTlpksvreginEFLDGYLPTENMRFREESI 252
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
25-205 |
2.56e-09 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 57.27 E-value: 2.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIdskelscmkEEALAKLRLteigfifqQSNLLRNL-- 102
Cdd:PRK11147 19 LDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIY---------EQDLIVARL--------QQDPPRNVeg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 103 NLFDNI---------ILSAY------LAKCESKKIVNK--RALELMENMG-------ISDI-------ASHYITEASGGQ 151
Cdd:PRK11147 82 TVYDFVaegieeqaeYLKRYhdishlVETDPSEKNLNElaKLQEQLDHHNlwqlenrINEVlaqlgldPDAALSSLSGGW 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446644341 152 LQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNInRGgtTIMLVTHD 205
Cdd:PRK11147 162 LRKAALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTF-QG--SIIFISHD 212
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
9-216 |
2.72e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 57.35 E-value: 2.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 9 QVNKTYSMDGNTNYHV-LKNIDleiyegEFvSVMGPSGSGKSTLLYNisgmdqmSSGSVKIDSKELScmkEEALAKLRlt 87
Cdd:PTZ00265 1235 DMTNEQDYQGDEEQNVgMKNVN------EF-SLTKEGGSGEDSTVFK-------NSGKILLDGVDIC---DYNLKDLR-- 1295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 88 EIGFIFQQSNLLRNLNLFDNIILSAYLAKCESKKIVNKRA-----LELMENMGISDIAShYITEASGGQLQRVSICRALI 162
Cdd:PTZ00265 1296 NLFSIVSQEPMLFNMSIYENIKFGKEDATREDVKRACKFAaidefIESLPNKYDTNVGP-YGKSLSGGQKQRIAIARALL 1374
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446644341 163 NNPNIIFADEPTGALNLKSTEEVMQILLNI-NRGGTTIMLVTHDVKVAAKTERIL 216
Cdd:PTZ00265 1375 REPKILLLDEATSSLDSNSEKLIEKTIVDIkDKADKTIITIAHRIASIKRSDKIV 1429
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
24-204 |
4.74e-09 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 54.85 E-value: 4.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKeealaklRLTEIGFIFQQSNLLRNLN 103
Cdd:PRK13543 26 VFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGD-------RSRFMAYLGHLPGLKADLS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVNKrALELmenMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTE 183
Cdd:PRK13543 99 TLENLHFLCGLHGRRAKQMPGS-ALAI---VGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGIT 174
|
170 180
....*....|....*....|.
gi 446644341 184 EVMQILLNINRGGTTIMLVTH 204
Cdd:PRK13543 175 LVNRMISAHLRGGGAALVTTH 195
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
2-224 |
5.61e-09 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 55.03 E-value: 5.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMD--QMSSGSVKIDSKELSCMKEE 79
Cdd:CHL00131 5 KPILEIKNLHASVN-----ENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPayKILEGDILFKGESILDLEPE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 ALAKLrltEIGFIFQQSNLLRNLNLFDNIILsAYLAKCESKKIVNKRALE----LMENMGISDIASHYITEA-----SGG 150
Cdd:CHL00131 80 ERAHL---GIFLAFQYPIEIPGVSNADFLRL-AYNSKRKFQGLPELDPLEfleiINEKLKLVGMDPSFLSRNvnegfSGG 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446644341 151 QLQRVSICRALINNPNIIFADEPTGALN---LKSTEEVMQILLNINRGgttIMLVTHDVKVA--AKTERILFMADGEIV 224
Cdd:CHL00131 156 EKKRNEILQMALLDSELAILDETDSGLDidaLKIIAEGINKLMTSENS---IILITHYQRLLdyIKPDYVHVMQNGKII 231
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
35-204 |
1.01e-08 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 55.62 E-value: 1.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 35 GEFVSVMGPSGSGKSTLLYNISGmdQMSSGSVKIDSKeLSCM--KEEALAKLRlteiGFIFQQSNLLRNLNLFDNIILSA 112
Cdd:PLN03140 906 GVLTALMGVSGAGKTTLMDVLAG--RKTGGYIEGDIR-ISGFpkKQETFARIS----GYCEQNDIHSPQVTVRESLIYSA 978
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 113 YL-----AKCESKKIVNKRALELMENMGISD--IASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEV 185
Cdd:PLN03140 979 FLrlpkeVSKEEKMMFVDEVMELVELDNLKDaiVGLPGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIV 1058
|
170
....*....|....*....
gi 446644341 186 MQILLNINRGGTTIMLVTH 204
Cdd:PLN03140 1059 MRTVRNTVDTGRTVVCTIH 1077
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
34-205 |
1.05e-08 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 55.18 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 34 EGEFVSVMGPSGSGKSTLLynisgmdQMSSGSVK----IDSKELScmKEEALAKLRLTEIGFIFQqsnllrnlNLFDNII 109
Cdd:COG1245 98 KGKVTGILGPNGIGKSTAL-------KILSGELKpnlgDYDEEPS--WDEVLKRFRGTELQDYFK--------KLANGEI 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 110 LSAY----------LAKCESKKIVNK-----RALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPT 174
Cdd:COG1245 161 KVAHkpqyvdlipkVFKGTVRELLEKvdergKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPS 240
|
170 180 190
....*....|....*....|....*....|.
gi 446644341 175 GALNLKSTEEVMQILLNINRGGTTIMLVTHD 205
Cdd:COG1245 241 SYLDIYQRLNVARLIRELAEEGKYVLVVEHD 271
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
3-227 |
1.26e-08 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 54.98 E-value: 1.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 3 KILEVKQVNKTYsmdGNTNYHVlKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALA 82
Cdd:PRK10522 321 QTLELRNVTFAY---QDNGFSV-GPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDYR 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KLrlteIGFIFQqsnllrNLNLFDniilsaYLAKCESKKIVNKRALELMENMGISD---IASHYI--TEASGGQLQRVSI 157
Cdd:PRK10522 397 KL----FSAVFT------DFHLFD------QLLGPEGKPANPALVEKWLERLKMAHkleLEDGRIsnLKLSKGQKKRLAL 460
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 158 CRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRG-GTTIMLVTHDVKVAAKTERILFMADGEIvSEI 227
Cdd:PRK10522 461 LLALAEERDILLLDEWAADQDPHFRREFYQVLLPLLQEmGKTIFAISHDDHYFIHADRLLEMRNGQL-SEL 530
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
24-221 |
1.37e-08 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 55.11 E-value: 1.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISG---MDQMSSGSVKIDSKELscmkEEALAKlrltEIGFIFQQSNLLR 100
Cdd:TIGR00956 778 ILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAErvtTGVITGGDRLVNGRPL----DSSFQR----SIGYVQQQDLHLP 849
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 NLNLFDNIILSAYL--AKCESKKIVNKRALELMENMGISDIASHYITEASGG----QLQRVSICRALINNPN-IIFADEP 173
Cdd:TIGR00956 850 TSTVRESLRFSAYLrqPKSVSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGlnveQRKRLTIGVELVAKPKlLLFLDEP 929
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446644341 174 TGALNLKSTEEVMQILLNINRGGTTIMLVTH--DVKVAAKTERILFMADG 221
Cdd:TIGR00956 930 TSGLDSQTAWSICKLMRKLADHGQAILCTIHqpSAILFEEFDRLLLLQKG 979
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
24-223 |
1.80e-08 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 54.95 E-value: 1.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMkeeALAKLRlTEIGFIFQQ----SNLL 99
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKI---GLHDLR-FKITIIPQDpvlfSGSL 1376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 100 R-NLNLFdniilSAYlakceSKKIVnKRALELMENMG----ISDIASHYITEA----SGGQLQRVSICRALINNPNIIFA 170
Cdd:TIGR00957 1377 RmNLDPF-----SQY-----SDEEV-WWALELAHLKTfvsaLPDKLDHECAEGgenlSVGQRQLVCLARALLRKTKILVL 1445
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446644341 171 DEPTGALNLKsTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEI 223
Cdd:TIGR00957 1446 DEATAAVDLE-TDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEV 1497
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
1-243 |
1.90e-08 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 54.65 E-value: 1.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSMDGNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKI-DSKELscmKEE 79
Cdd:PTZ00265 377 LKDIKKIQFKNVRFHYDTRKDVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIInDSHNL---KDI 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 ALAKLRlTEIGFIFQQSNLLRNlNLFDNIILSAY-----------------------------LAKC-----------ES 119
Cdd:PTZ00265 454 NLKWWR-SKIGVVSQDPLLFSN-SIKNNIKYSLYslkdlealsnyynedgndsqenknkrnscRAKCagdlndmsnttDS 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 120 KKIVN-KRALELMENMGISDIASHYI--------------------TEASGGQLQRVSICRALINNPNIIFADEPTGALN 178
Cdd:PTZ00265 532 NELIEmRKNYQTIKDSEVVDVSKKVLihdfvsalpdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLD 611
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 179 LKSTEEVMQILLNI--NRGGTTImLVTHDVKVAAKTERILFMADGEIVSEIQLGKLRNDDLKAREEK 243
Cdd:PTZ00265 612 NKSEYLVQKTINNLkgNENRITI-IIAHRLSTIRYANTIFVLSNRERGSTVDVDIIGEDPTKDNKEN 677
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
28-246 |
5.87e-08 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 52.99 E-value: 5.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 28 IDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELS--------------C---MKEEALAKLRLTEig 90
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDirsprdairagimlCpedRKAEGIIPVHSVA-- 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 91 fifqqsnllrnlnlfDNIILSAYLAKCESKKIVNKRAlelmEnmgiSDIASHYITEA--------------SGGQLQRVS 156
Cdd:PRK11288 350 ---------------DNINISARRHHLRAGCLINNRW----E----AENADRFIRSLniktpsreqlimnlSGGNQQKAI 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 157 ICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEIVSEIqlgkLRND 235
Cdd:PRK11288 407 LGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLpEVLGVADRIVVMREGRIAGEL----AREQ 482
|
250
....*....|.
gi 446644341 236 dlkAREEKLLN 246
Cdd:PRK11288 483 ---ATERQALS 490
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
3-205 |
8.99e-08 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 52.24 E-value: 8.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 3 KILEVKQVNKTYsmDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKI-DSKELSCMKEeal 81
Cdd:TIGR03719 321 KVIEAENLTKAF--GDKL---LIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIgETVKLAYVDQ--- 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 aklrlteigfifQQSNLLRNLNLF-------DNIILsaylakceSKKIVNKRALELMENMGISDiASHYITEASGGQLQR 154
Cdd:TIGR03719 393 ------------SRDALDPNKTVWeeisgglDIIKL--------GKREIPSRAYVGRFNFKGSD-QQKKVGQLSGGERNR 451
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446644341 155 VSICRALINNPNIIFADEPTGALN---LKSTEEVmqiLLNInrgGTTIMLVTHD 205
Cdd:TIGR03719 452 VHLAKTLKSGGNVLLLDEPTNDLDvetLRALEEA---LLNF---AGCAVVISHD 499
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
31-206 |
9.08e-08 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 52.50 E-value: 9.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 31 EIYEGEFVSVMGPSGSGKSTLLynisgmdQMSSGSVKIDSKELScmkeealAKLRLT------EIGFIFQQSNLLRNLNl 104
Cdd:PRK13409 361 EIYEGEVIGIVGPNGIGKTTFA-------KLLAGVLKPDEGEVD-------PELKISykpqyiKPDYDGTVEDLLRSIT- 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 105 fdNIILSAYLAkceskkivnkraLELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALNLkstEE 184
Cdd:PRK13409 426 --DDLGSSYYK------------SEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDV---EQ 488
|
170 180
....*....|....*....|....*.
gi 446644341 185 VMQILLNINR----GGTTIMLVTHDV 206
Cdd:PRK13409 489 RLAVAKAIRRiaeeREATALVVDHDI 514
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
23-226 |
1.46e-07 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 50.72 E-value: 1.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYN-------------IS-----GMDQMS----------SGSVKIDSKELS 74
Cdd:cd03270 9 HNLKNVDVDIPRNKLVVITGVSGSGKSSLAFDtiyaegqrryvesLSayarqFLGQMDkpdvdsieglSPAIAIDQKTTS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 75 cmkeealAKLRLTeIGFIFQQSNLLRnlNLFDNIILsaylakceskkivnKRALELMENMGIsdiasHYIT---EA---S 148
Cdd:cd03270 89 -------RNPRST-VGTVTEIYDYLR--LLFARVGI--------------RERLGFLVDVGL-----GYLTlsrSAptlS 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 149 GGQLQRVSICRALINN-PNIIFA-DEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMA------D 220
Cdd:cd03270 140 GGEAQRIRLATQIGSGlTGVLYVlDEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVEHDEDTIRAADHVIDIGpgagvhG 219
|
....*.
gi 446644341 221 GEIVSE 226
Cdd:cd03270 220 GEIVAQ 225
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
25-224 |
1.74e-07 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 50.34 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 25 LKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMS---SGSVKIDSKELSCMKEEALAklrltEIGFIFQQSNLLRN 101
Cdd:cd03233 23 LKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEKYPG-----EIIYVSEEDVHFPT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 102 LNLFDNIILSAylaKCESKKIVNkralelmenmGISdiashyiteasGGQLQRVSICRALINNPNIIFADEPTGALNLKS 181
Cdd:cd03233 98 LTVRETLDFAL---RCKGNEFVR----------GIS-----------GGERKRVSIAEALVSRASVLCWDNSTRGLDSST 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446644341 182 TEEVMQILLNINR--GGTTIMLVTH-DVKVAAKTERILFMADGEIV 224
Cdd:cd03233 154 ALEILKCIRTMADvlKTTTFVSLYQaSDEIYDLFDKVLVLYEGRQI 199
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
24-224 |
2.67e-07 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 50.29 E-value: 2.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMKEEALaKLRLTEIgfifqqsnlLRNLN 103
Cdd:cd03288 36 VLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTL-RSRLSII---------LQDPI 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVNKRALEL--MENM------GISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTG 175
Cdd:cd03288 106 LFSGSIRFNLDPECKCTDDRLWEALEIaqLKNMvkslpgGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATA 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446644341 176 ALNLkSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:cd03288 186 SIDM-ATENILQKVVMTAFADRTVVTIAHRVSTILDADLVLVLSRGILV 233
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
19-204 |
2.93e-07 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 49.56 E-value: 2.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 19 NTNYH---VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELScmKEEALAKLRLTeigFIFQQ 95
Cdd:PRK13540 8 DFDYHdqpLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIK--KDLCTYQKQLC---FVGHR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 96 SNLLRNLNLFDNIILSAYLAKceskkivnkralelmENMGISDIAS-----HYITEASG----GQLQRVSICRALINNPN 166
Cdd:PRK13540 83 SGINPYLTLRENCLYDIHFSP---------------GAVGITELCRlfsleHLIDYPCGllssGQKRQVALLRLWMSKAK 147
|
170 180 190
....*....|....*....|....*....|....*...
gi 446644341 167 IIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTH 204
Cdd:PRK13540 148 LWLLDEPLVALDELSLLTIITKIQEHRAKGGAVLLTSH 185
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
31-206 |
4.11e-07 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 50.55 E-value: 4.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 31 EIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSK------------ELSCmkEEALAKLRLTEIGFIFQQSNL 98
Cdd:COG1245 362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLKisykpqyispdyDGTV--EEFLRSANTDDFGSSYYKTEI 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 99 LRNLNLfdniilsaylakcesKKIVNKralelmenmgisdiashYITEASGGQLQRVSICRALINNPNIIFADEPTGALN 178
Cdd:COG1245 440 IKPLGL---------------EKLLDK-----------------NVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 487
|
170 180 190
....*....|....*....|....*....|..
gi 446644341 179 LkstEEVMQILLNINR----GGTTIMLVTHDV 206
Cdd:COG1245 488 V---EQRLAVAKAIRRfaenRGKTAMVVDHDI 516
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
5-235 |
5.16e-07 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 49.47 E-value: 5.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQmSSGSVKIDSKELSCMkeeALAKL 84
Cdd:cd03289 3 MTVKDLTAKYTEGGNA---VLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSV---PLQKW 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 R-----LTEIGFIFQQSnLLRNLNLFDniilsaylakceskKIVNKRALELMENMGISDIASHYITE-----------AS 148
Cdd:cd03289 76 RkafgvIPQKVFIFSGT-FRKNLDPYG--------------KWSDEEIWKVAEEVGLKSVIEQFPGQldfvlvdggcvLS 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 149 GGQLQRVSICRALINNPNIIFADEPTGALNlKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIVSEIQ 228
Cdd:cd03289 141 HGHKQLMCLARSVLSKAKILLLDEPSAHLD-PITYQVIRKTLKQAFADCTVILSEHRIEAMLECQRFLVIEENKVRQYDS 219
|
....*..
gi 446644341 229 LGKLRND 235
Cdd:cd03289 220 IQKLLNE 226
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
2-55 |
5.20e-07 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 50.07 E-value: 5.20e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 446644341 2 KKILEVKQVNKtysmdgntnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNI 55
Cdd:PRK00349 612 GKFLKLKGARE----------NNLKNVDVEIPLGKFTCVTGVSGSGKSTLINET 655
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
2-55 |
5.44e-07 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 50.01 E-value: 5.44e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 446644341 2 KKILEVKQVNKtysmdgntnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNI 55
Cdd:TIGR00630 611 GKFLTLKGARE----------NNLKNITVSIPLGLFTCITGVSGSGKSTLINDT 654
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
23-55 |
1.21e-06 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 48.38 E-value: 1.21e-06
10 20 30
....*....|....*....|....*....|...
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNI 55
Cdd:cd03271 9 NNLKNIDVDIPLGVLTCVTGVSGSGKSSLINDT 41
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
4-223 |
1.55e-06 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 48.57 E-value: 1.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNktysmdgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMK-EEALA 82
Cdd:PRK10982 250 ILEVRNLT-------SLRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNaNEAIN 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 83 KlrlteiGFIF-----QQSNLLRNLNL-FDNII--LSAYLAKCE--SKKIVNKRALELMENMGISdIASHY--ITEASGG 150
Cdd:PRK10982 323 H------GFALvteerRSTGIYAYLDIgFNSLIsnIRNYKNKVGllDNSRMKSDTQWVIDSMRVK-TPGHRtqIGSLSGG 395
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446644341 151 QLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEI 223
Cdd:PRK10982 396 NQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMpELLGITDRILVMSNGLV 469
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
23-51 |
1.62e-06 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 48.87 E-value: 1.62e-06
10 20
....*....|....*....|....*....
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTL 51
Cdd:COG0178 14 HNLKNIDVDIPRNKLVVITGLSGSGKSSL 42
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
4-73 |
2.01e-06 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 47.48 E-value: 2.01e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446644341 4 ILEVKQVNktYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMD--QMSSGSVKIDSKEL 73
Cdd:PRK09580 1 MLSIKDLH--VSVEDKA---ILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDL 67
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
17-228 |
2.08e-06 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 48.09 E-value: 2.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 17 DGNTNYH---VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGmD--------------QMSSGSVKIDSKElscmkee 79
Cdd:PRK10938 265 NGVVSYNdrpILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG-DhpqgysndltlfgrRRGSGETIWDIKK------- 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 80 alaklrltEIGFIFQQSNL-------LRNLNL---FDNIILsaYLAKCESKKivnKRALELMENMGISD-IASHYITEAS 148
Cdd:PRK10938 337 --------HIGYVSSSLHLdyrvstsVRNVILsgfFDSIGI--YQAVSDRQQ---KLAQQWLDILGIDKrTADAPFHSLS 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 149 GGQLQRVSICRALINNPNIIFADEPTGAL---NLKSTEEVMQILlnINRGGTTIMLVTHDVKVAAK--TERILFMADGEI 223
Cdd:PRK10938 404 WGQQRLALIVRALVKHPTLLILDEPLQGLdplNRQLVRRFVDVL--ISEGETQLLFVSHHAEDAPAciTHRLEFVPDGDI 481
|
....*
gi 446644341 224 VSEIQ 228
Cdd:PRK10938 482 YRYVQ 486
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
23-55 |
2.26e-06 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 48.10 E-value: 2.26e-06
10 20 30
....*....|....*....|....*....|...
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNI 55
Cdd:COG0178 619 NNLKNVDVEIPLGVLTCVTGVSGSGKSTLVNDI 651
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
4-204 |
2.69e-06 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 47.86 E-value: 2.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYSmdgntNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSS--GSVKIDSKELscmkeeAL 81
Cdd:NF040905 1 ILEMRGITKTFP-----GVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyeGEILFDGEVC------RF 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 AKLRLTE---IGFIFQQSNLLRNLNLFDNIILSAYLAKcesKKIVN-----KRALELMENMGISDIASHYITEASGGQLQ 153
Cdd:NF040905 70 KDIRDSEalgIVIIHQELALIPYLSIAENIFLGNERAK---RGVIDwnetnRRARELLAKVGLDESPDTLVTDIGVGKQQ 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTH 204
Cdd:NF040905 147 LVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSIIISH 197
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
23-54 |
2.90e-06 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 48.09 E-value: 2.90e-06
10 20 30
....*....|....*....|....*....|..
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYN 54
Cdd:TIGR00630 10 HNLKNIDVEIPRDKLVVITGLSGSGKSSLAFD 41
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
21-221 |
3.03e-06 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 46.16 E-value: 3.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 21 NYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISgmdqmssgsvkidSKELSCMKEEALAKLRLTEIGFIFQQSNLLr 100
Cdd:cd03238 7 NVHNLQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGL-------------YASGKARLISFLPKFSRNKLIFIDQLQFLI- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 101 NLNLfdniilsAYLAkceskkivnkraleLMENMGisdiashyitEASGGQLQRVSICRALINNP--NIIFADEPTGALN 178
Cdd:cd03238 73 DVGL-------GYLT--------------LGQKLS----------TLSGGELQRVKLASELFSEPpgTLFILDEPSTGLH 121
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446644341 179 LKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADG 221
Cdd:cd03238 122 QQDINQLLEVIKGLIDLGNTVILIEHNLDVLSSADWIIDFGPG 164
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
19-223 |
4.69e-06 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 47.13 E-value: 4.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 19 NTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGM-DQMSSGSVKIDSKEL---SCMKEEALAKLRLTEIGfifQ 94
Cdd:TIGR02633 270 NPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAyPGKFEGNVFINGKPVdirNPAQAIRAGIAMVPEDR---K 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 95 QSNLLRNLNLFDNIILSAyLAKCESKKIVNKRALELMENMGISDI---ASH---YITEASGGQLQRVSICRALINNPNII 168
Cdd:TIGR02633 347 RHGIVPILGVGKNITLSV-LKSFCFKMRIDAAAELQIIGSAIQRLkvkTASpflPIGRLSGGNQQKAVLAKMLLTNPRVL 425
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 169 FADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGEI 223
Cdd:TIGR02633 426 ILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELaEVLGLSDRVLVIGEGKL 481
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
4-174 |
8.33e-06 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 46.66 E-value: 8.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNKTYsmdGNTnyHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKI---DskelscMKEEA 80
Cdd:NF033858 1 VARLEGVSHRY---GKT--VALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVlggD------MADAR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 81 LAKLRLTEIGFIFQ--QSNLLRNLNLFDNIILSAYL-----AKCEskkivnKRALELMENMGISDIASHYITEASGGQLQ 153
Cdd:NF033858 70 HRRAVCPRIAYMPQglGKNLYPTLSVFENLDFFGRLfgqdaAERR------RRIDELLRATGLAPFADRPAGKLSGGMKQ 143
|
170 180
....*....|....*....|.
gi 446644341 154 RVSICRALINNPNIIFADEPT 174
Cdd:NF033858 144 KLGLCCALIHDPDLLILDEPT 164
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
148-222 |
1.99e-05 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 44.10 E-value: 1.99e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446644341 148 SGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLN-INRGGTTIMLVTHDVKVAAKTERILFMADGE 222
Cdd:cd03222 73 SGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRlSEEGKKTALVVEHDLAVLDYLSDRIHVFEGE 148
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
23-51 |
4.34e-05 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 44.29 E-value: 4.34e-05
10 20
....*....|....*....|....*....
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTL 51
Cdd:PRK00349 14 HNLKNIDLDIPRDKLVVFTGLSGSGKSSL 42
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
34-205 |
6.48e-05 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 43.64 E-value: 6.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 34 EGEFVSVMGPSGSGKSTLLyNISgmdqmsSGSVK----IDSKELScmKEEALAKLRLTEIGFIFQQsnllrnlnLFDNII 109
Cdd:PRK13409 98 EGKVTGILGPNGIGKTTAV-KIL------SGELIpnlgDYEEEPS--WDEVLKRFRGTELQNYFKK--------LYNGEI 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 110 LSA-------YLAKC------ESKKIVNKR--ALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPT 174
Cdd:PRK13409 161 KVVhkpqyvdLIPKVfkgkvrELLKKVDERgkLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPT 240
|
170 180 190
....*....|....*....|....*....|.
gi 446644341 175 GALNLKSTEEVMQILLNINRgGTTIMLVTHD 205
Cdd:PRK13409 241 SYLDIRQRLNVARLIRELAE-GKYVLVVEHD 270
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
24-224 |
8.75e-05 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 43.57 E-value: 8.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMkeeALAKLRlTEIGFIFQQ----SNLL 99
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKF---GLMDLR-KVLGIIPQApvlfSGTV 1329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 100 R-NLNLF---DNIILSAYLAKCESKKIVNKRALELmeNMGISDIASHYiteaSGGQLQRVSICRALINNPNIIFADEPTG 175
Cdd:PLN03130 1330 RfNLDPFnehNDADLWESLERAHLKDVIRRNSLGL--DAEVSEAGENF----SVGQRQLLSLARALLRRSKILVLDEATA 1403
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446644341 176 ALNLKsTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERILFMADGEIV 224
Cdd:PLN03130 1404 AVDVR-TDALIQKTIREEFKSCTMLIIAHRLNTIIDCDRILVLDAGRVV 1451
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
2-223 |
1.02e-04 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 43.02 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 2 KKILEVKQVNktYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKelscmkeeal 81
Cdd:PRK11147 317 KIVFEMENVN--YQIDGKQ---LVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCGTK---------- 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 82 aklrlTEIGFifqqsnllrnlnlFDNiilsaYLAKCESKKIVnkralelMENMG-------ISDIASH---YITE----- 146
Cdd:PRK11147 382 -----LEVAY-------------FDQ-----HRAELDPEKTV-------MDNLAegkqevmVNGRPRHvlgYLQDflfhp 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 147 ---------ASGGQLQRVSICRALINNPNIIFADEPTGALNLKsTEEVMQILLNINRGgtTIMLVTHDVKVA--AKTERI 215
Cdd:PRK11147 432 kramtpvkaLSGGERNRLLLARLFLKPSNLLILDEPTNDLDVE-TLELLEELLDSYQG--TVLLVSHDRQFVdnTVTECW 508
|
....*...
gi 446644341 216 LFMADGEI 223
Cdd:PRK11147 509 IFEGNGKI 516
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
5-224 |
1.11e-04 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 42.96 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 5 LEVKQVNKTYsmDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKidskelscMKEEAlakl 84
Cdd:PRK15064 320 LEVENLTKGF--DNGP---LFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVK--------WSENA---- 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 85 rltEIGFIFQQS--NLLRNLNLFDNIilSAYLAKCESKKIVnkRALeLMENMGISDIASHYITEASGGQLQRVSICRALI 162
Cdd:PRK15064 383 ---NIGYYAQDHayDFENDLTLFDWM--SQWRQEGDDEQAV--RGT-LGRLLFSQDDIKKSVKVLSGGEKGRMLFGKLMM 454
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446644341 163 NNPNIIFADEPTGALNLKSTEEvMQILLNINRGgtTIMLVTHDVK-VAAKTERILFMADGEIV 224
Cdd:PRK15064 455 QKPNVLVMDEPTNHMDMESIES-LNMALEKYEG--TLIFVSHDREfVSSLATRIIEITPDGVV 514
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
3-68 |
1.52e-04 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 42.41 E-value: 1.52e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 3 KILEVKQVNKTYsmdGNtnyHVL-KNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKI 68
Cdd:PRK11819 323 KVIEAENLSKSF---GD---RLLiDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI 383
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
1-206 |
1.74e-04 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 42.57 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 1 MKKILEVKQVNKTYSM--------------DGNTNYH-VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGS 65
Cdd:PRK13545 1 MNYKVKFEHVTKKYKMynkpfdklkdlffrSKDGEYHyALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 66 VKIDSKElscmkeealaklRLTEIGfifqqSNLLRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYIT 145
Cdd:PRK13545 81 VDIKGSA------------ALIAIS-----SGLNGQLTGIENIELKGLMMGLTKEKI-KEIIPEIIEFADIGKFIYQPVK 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 146 EASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV 206
Cdd:PRK13545 143 TYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDKMNEFKEQGKTIFFISHSL 203
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
42-205 |
1.91e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 41.44 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 42 GPSGSGKSTLL----YNISGMDQMSSGSVKIDSKelSCMKEEALAKLRLTEIGFIFQQSNLLRNLNLFDNIIlsaYLAKC 117
Cdd:cd03240 29 GQNGAGKTTIIealkYALTGELPPNSKGGAHDPK--LIREGEVRAQVKLAFENANGKKYTITRSLAILENVI---FCHQG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 118 ESKKIvnkraLELMenmgisdiashyITEASGGQ------LQRVSICRALINNPNIIFADEPTGALNLKSTEEVM-QILL 190
Cdd:cd03240 104 ESNWP-----LLDM------------RGRCSGGEkvlaslIIRLALAETFGSNCGILALDEPTTNLDEENIEESLaEIIE 166
|
170
....*....|....*.
gi 446644341 191 NINRGGT-TIMLVTHD 205
Cdd:cd03240 167 ERKSQKNfQLIVITHD 182
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
4-245 |
3.88e-04 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 41.07 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 4 ILEVKQVNkTYSMDgNTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQ-MSSGSVKIDSKELS-------- 74
Cdd:PRK13549 259 ILEVRNLT-AWDPV-NPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKPVKirnpqqai 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 75 ----CMKEEALAKLRLTEIgfifqqsnllrnLNLFDNIILSAYLAKCESKKIVN----KRALELMENMGISdiASH---Y 143
Cdd:PRK13549 337 aqgiAMVPEDRKRDGIVPV------------MGVGKNITLAALDRFTGGSRIDDaaelKTILESIQRLKVK--TASpelA 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 144 ITEASGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDV-KVAAKTERILFMADGE 222
Cdd:PRK13549 403 IARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELpEVLGLSDRVLVMHEGK 482
|
250 260
....*....|....*....|...
gi 446644341 223 IVseiqlGKLRNDDLKarEEKLL 245
Cdd:PRK13549 483 LK-----GDLINHNLT--QEQVM 498
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
5-74 |
4.05e-04 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 41.32 E-value: 4.05e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 5 LEVKQVNKTY-SMDGNTNYHVlKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELS 74
Cdd:COG4615 328 LELRGVTYRYpGEDGDEGFTL-GPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVT 397
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
24-227 |
9.34e-04 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 40.53 E-value: 9.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 24 VLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKELSCMkeeALAKLRLteigfifQQSNLLRNLN 103
Cdd:PTZ00243 1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAY---GLRELRR-------QFSMIPQDPV 1394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 104 LFDNIILSAYLAKCESKKIVNKRALELM--------ENMGIS----DIASHYiteaSGGQLQRVSICRALIN-NPNIIFA 170
Cdd:PTZ00243 1395 LFDGTVRQNVDPFLEASSAEVWAALELVglrervasESEGIDsrvlEGGSNY----SVGQRQLMCMARALLKkGSGFILM 1470
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446644341 171 DEPTG----ALNLKSTEEVMQILLNInrggtTIMLVTHDVKVAAKTERILFMADGeIVSEI 227
Cdd:PTZ00243 1471 DEATAnidpALDRQIQATVMSAFSAY-----TVITIAHRLHTVAQYDKIIVMDHG-AVAEM 1525
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
19-207 |
9.66e-04 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 39.41 E-value: 9.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 19 NTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKidskelscmkeealaklRLTEIGFIFQQSNL 98
Cdd:PRK13546 34 NKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVD-----------------RNGEVSVIAISAGL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 99 LRNLNLFDNIILSAYLAKCESKKIvNKRALELMENMGISDIASHYITEASGGQLQRVSICRALINNPNIIFADEPTGALN 178
Cdd:PRK13546 97 SGQLTGIENIEFKMLCMGFKRKEI-KAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGD 175
|
170 180
....*....|....*....|....*....
gi 446644341 179 LKSTEEVMQILLNINRGGTTIMLVTHDVK 207
Cdd:PRK13546 176 QTFAQKCLDKIYEFKEQNKTIFFVSHNLG 204
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
93-216 |
1.25e-03 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 39.81 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 93 FQQSNLlRNLNLFDNIILSAYLAKCESKKIVNKRaLELMENMGISDIA-SHYITEASGGQLQRVSICRAL---INNPNII 168
Cdd:PRK00635 424 FQQMSL-QELFIFLSQLPSKSLSIEEVLQGLKSR-LSILIDLGLPYLTpERALATLSGGEQERTALAKHLgaeLIGITYI 501
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 446644341 169 FaDEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHDVKVAAKTERIL 216
Cdd:PRK00635 502 L-DEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVEHDEQMISLADRII 548
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
5-69 |
2.15e-03 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 39.12 E-value: 2.15e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446644341 5 LEVKQVNKTYSMDGNTnyhVLKNIDLEIYEGEFVSVMGPSGSGKSTLLyniSGMDQMSS--GSVKID 69
Cdd:TIGR01271 1218 MDVQGLTAKYTEAGRA---VLQDLSFSVEGGQRVGLLGRTGSGKSTLL---SALLRLLSteGEIQID 1278
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
148-209 |
2.96e-03 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 38.66 E-value: 2.96e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446644341 148 SGGQLQRVSICRALIN---NPNIIFADEPTGALNLKSTEEVMQILLNINRGGTTIMLVTHD---VKVA 209
Cdd:PRK00635 811 SGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIIEHNmhvVKVA 878
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
19-55 |
4.91e-03 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 38.27 E-value: 4.91e-03
10 20 30
....*....|....*....|....*....|....*..
gi 446644341 19 NTNYHVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNI 55
Cdd:PRK00635 945 NAYQHNLKHIDLSLPRNALTAVTGPSASGKHSLVFDI 981
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
23-221 |
5.92e-03 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 36.57 E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 23 HVLKNIDLEIYEGEFVSVMGPSGSGKSTLLYNISgmdqmssgsvkidskelscmkeealaklrlteIGFIFQQSNLLRNl 102
Cdd:cd03227 9 SYFVPNDVTFGEGSLTIITGPNGSGKSTILDAIG--------------------------------LALGGAQSATRRR- 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 103 nlfdniilSAYLAKCESkkivnkrALELMENMGIsdiashyITEASGGQLQRVSICRALINN-----PNIIFaDEPTGAL 177
Cdd:cd03227 56 --------SGVKAGCIV-------AAVSAELIFT-------RLQLSGGEKELSALALILALAslkprPLYIL-DEIDRGL 112
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446644341 178 NLKSTEEVMQILLNINRGGTTIMLVTHD---VKVAAKTERILFMADG 221
Cdd:cd03227 113 DPRDGQALAEAILEHLVKGAQVIVITHLpelAELADKLIHIKKVITG 159
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
35-224 |
6.05e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 36.20 E-value: 6.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 35 GEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIdskeLSCMKEEALAKLRLTEIGFIFQQSNLlrnlnlfdniilsayl 114
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIY----IDGEDILEEVLDQLLLIIVGGKKASG---------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 115 akceskkivnkralelmenmgisdiashyiteaSGGQLQRVSICRALINNPNIIFADEPTGALNLKSTEEVMQI------ 188
Cdd:smart00382 62 ---------------------------------SGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLeelrll 108
|
170 180 190
....*....|....*....|....*....|....*.
gi 446644341 189 LLNINRGGTTIMLVTHDVKVAAKTErILFMADGEIV 224
Cdd:smart00382 109 LLLKSEKNLTVILTTNDEKDLGPAL-LRRRFDRRIV 143
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
27-205 |
9.08e-03 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 37.18 E-value: 9.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 27 NIDLEIYEGEFVSVMGPSGSGKSTLLYNISGMDQMSSGSVKIDSKElscmkeeALAKLRLTEigFIFQQSNLLrnlnlfD 106
Cdd:PRK15064 19 NISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNE-------RLGKLRQDQ--FAFEEFTVL------D 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446644341 107 NIIL---SAYLAKCESKKIVNK----------------------------RALELMENMGIsDIASHY--ITEASGGQLQ 153
Cdd:PRK15064 84 TVIMghtELWEVKQERDRIYALpemseedgmkvadlevkfaemdgytaeaRAGELLLGVGI-PEEQHYglMSEVAPGWKL 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446644341 154 RVSICRALINNPNIIFADEPTGALNLKSTEEVMQILLNINrggTTIMLVTHD 205
Cdd:PRK15064 163 RVLLAQALFSNPDILLLDEPTNNLDINTIRWLEDVLNERN---STMIIISHD 211
|
|
| |
