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Conserved domains on  [gi|446650124|ref|WP_000727470|]
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MULTISPECIES: peptidylprolyl isomerase PrsA [Bacillus]

Protein Classification

peptidylprolyl isomerase PrsA( domain architecture ID 11479868)

peptidylprolyl isomerase PrsA plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins, and it functions as a peptidyl-prolyl cis-trans isomerase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

EC:  5.2.1.8
Gene Ontology:  GO:0003755|GO:0006457
PubMed:  10228556

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 1-283 8.95e-162

peptidylprolyl isomerase; Reviewed


:

Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 450.58  E-value: 8.95e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124   1 MKKKKLFLGTIISCVVLALSACGSSDNVVTSKVGNITEKELSKELKQKYGESTLYQMVLSKALLDKYKVSDEEAKKQVEE 80
Cdd:PRK02998   1 MKKKKLFLGTIISCVVLALSACGSSDNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKYKVSDEEAKKQVEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  81 AKDKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNNGED 160
Cdd:PRK02998  81 AKDKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNNGED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 161 FAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKELKPFDEVKDSIRKDI 240
Cdd:PRK02998 161 FAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKELKPFDEVKDSIRKDL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446650124 241 EQQRLQDTTGKWKQQVVNELLKDADIKVNDKEFKNTFEFLEKK 283
Cdd:PRK02998 241 EQQRLQDTTGKWKQQVVNDLLKDADIKVNDKEFKDTFKFLEKK 283
 
Name Accession Description Interval E-value
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 1-283 8.95e-162

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 450.58  E-value: 8.95e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124   1 MKKKKLFLGTIISCVVLALSACGSSDNVVTSKVGNITEKELSKELKQKYGESTLYQMVLSKALLDKYKVSDEEAKKQVEE 80
Cdd:PRK02998   1 MKKKKLFLGTIISCVVLALSACGSSDNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKYKVSDEEAKKQVEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  81 AKDKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNNGED 160
Cdd:PRK02998  81 AKDKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNNGED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 161 FAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKELKPFDEVKDSIRKDI 240
Cdd:PRK02998 161 FAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKELKPFDEVKDSIRKDL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446650124 241 EQQRLQDTTGKWKQQVVNELLKDADIKVNDKEFKNTFEFLEKK 283
Cdd:PRK02998 241 EQQRLQDTTGKWKQQVVNDLLKDADIKVNDKEFKDTFKFLEKK 283
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 132-256 2.68e-43

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 144.33  E-value: 2.68e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 132 KPEMKVSHILV---------KDEKTAKEVKEKVNNGEDFAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDA 202
Cdd:COG0760    6 PEEVRASHILVkvppsedraKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALKP 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446650124 203 GQVSEPVKTTYGYHIIKVTDKKE--LKPFDEVKDSIRKDIEQQRLQDTTGKWKQQV 256
Cdd:COG0760   86 GEISGPVKTQFGYHIIKVEDRRPaeTPPFEEVKQQIRQELFQQALEAWLEELRKKA 141
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 136-224 7.29e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 101.29  E-value: 7.29e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  136 KVSHILV-------KDEKTAK----EVKEKVNNGEDFAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAGQ 204
Cdd:pfam13616  17 KASHILIsysqavsRTEEEAKakadSLLAALKNGADFAALAKTYSDDPASKNNGGDLGWFTKGQMVKEFEDAVFSLKVGE 96

                          90       100
                  ....*....|....*....|
gi 446650124  205 VSEPVKTTYGYHIIKVTDKK 224
Cdd:pfam13616  97 ISGVVKTQFGFHIIKVTDKK 116
 
Name Accession Description Interval E-value
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 1-283 8.95e-162

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 450.58  E-value: 8.95e-162
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124   1 MKKKKLFLGTIISCVVLALSACGSSDNVVTSKVGNITEKELSKELKQKYGESTLYQMVLSKALLDKYKVSDEEAKKQVEE 80
Cdd:PRK02998   1 MKKKKLFLGTIISCVVLALSACGSSDNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKYKVSDEEAKKQVEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  81 AKDKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNNGED 160
Cdd:PRK02998  81 AKDKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNNGED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 161 FAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKELKPFDEVKDSIRKDI 240
Cdd:PRK02998 161 FAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKELKPFDEVKDSIRKDL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446650124 241 EQQRLQDTTGKWKQQVVNELLKDADIKVNDKEFKNTFEFLEKK 283
Cdd:PRK02998 241 EQQRLQDTTGKWKQQVVNDLLKDADIKVNDKEFKDTFKFLEKK 283
prsA PRK03002
peptidylprolyl isomerase PrsA;
1-283 2.74e-85

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 256.79  E-value: 2.74e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124   1 MKKKKLFLGTIIsCVVLALSACG---SSDNVVTSKVGNITEKELSKELKQKYGESTLYQMVLSKALLDKYKVSDEEAKKQ 77
Cdd:PRK03002   1 MRGKHIFIITAL-ISILMLSACGqknSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  78 VEEAKDKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNN 157
Cdd:PRK03002  80 VQKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 158 GEDFAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKELKPFDEVKDSIR 237
Cdd:PRK03002 160 GASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKDLKPYDEVKDSIR 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 446650124 238 KDIEQQRLQDTTgkWKQQVVNELLKDADIKVNDKEFKNTFEFLEKK 283
Cdd:PRK03002 240 KNLEEERTADPI--FGKKLLQSELKKANIKINDSELEDTFTIVSPQ 283
prsA PRK03095
peptidylprolyl isomerase PrsA;
1-278 3.85e-71

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 220.64  E-value: 3.85e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124   1 MKKKKLFLGtiiSCVVLALSACG--SSDNVVTSKVGNITEKELSKELKQKYGESTLYQMVLSKALLDKYKVSDEEAKKQV 78
Cdd:PRK03095   1 MKKAMLALA---ATSVIALSACGtsSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  79 EEAKDKMGDNFKSTLEQVGLKnEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNNG 158
Cdd:PRK03095  78 DEMKKQYGDQFDTLLKQQGIK-EETLKTGVRAQLAQEKAIEKTITDKELKDNYKPEIKASHILVKDEATAKKVKEELGQG 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 159 EDFAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKEL-KPFDEVKDSIR 237
Cdd:PRK03095 157 KSFEELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVTDIKEPeKSFEQSKADIK 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 446650124 238 KDIEQQRLQDttGKWKQQVVNELLKDADIKVNDKEFKNTFE 278
Cdd:PRK03095 237 KELVQKKAQD--GEFMNDLMMKEIKKADVKVDDKDLKDLFE 275
prsA PRK04405
peptidylprolyl isomerase; Provisional
 1-275 4.50e-44

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 151.47  E-value: 4.50e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124   1 MKK--KKLFLGTIISCVVLALSACGSSDN-VVTSKVGNITEKELSKELKQ-KYGESTLYQMVLSKALLDKY--KVSDEEA 74
Cdd:PRK04405   1 MKKkmKKWALAAASAGLALSLAGCSSNQAtVATYSGGKITQSQYYKEMKQsSAGKTVLANMIIYRALEKQYgkKVSTKKV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  75 KKQVEEAKDKMGDNFKSTLEQVGLkNEDELKEKMKPEIAFEKAIKA--TVTEKDVKD---NYKPEMKVSHILVKDEKTAK 149
Cdd:PRK04405  81 DKQYNSYKKQYGSSFDSVLSQNGM-TTSSFKQNLRTNLLSEAALKKlkKVTNSQLKKawkSYQPKVTVQHILVSKKSTAE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 150 EVKEKVNNGEDFAALAKQYSEDTGSKEQGGEITGFAPGQTV--KEFEEAAYKLDAGQV-SEPVKTTYGYHIIKVTDKKEL 226
Cdd:PRK04405 160 TVIKKLKDGKDFAKLAKKYSTDTATKNKGGKLSAFDSTDTTldSTFKTAAFKLKNGEYtTTPVKTTYGYEVIKMIKHPAK 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 446650124 227 KPFDEVKDSIRKDIEQQRLQDTTGkwKQQVVNELLKDADIKVNDKEFKN 275
Cdd:PRK04405 240 GTFSDHKKALTKQIYAKWASDSSV--MQRVISKVLKKANVSIKDKDLKD 286
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 132-256 2.68e-43

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 144.33  E-value: 2.68e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 132 KPEMKVSHILV---------KDEKTAKEVKEKVNNGEDFAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDA 202
Cdd:COG0760    6 PEEVRASHILVkvppsedraKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALKP 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446650124 203 GQVSEPVKTTYGYHIIKVTDKKE--LKPFDEVKDSIRKDIEQQRLQDTTGKWKQQV 256
Cdd:COG0760   86 GEISGPVKTQFGYHIIKVEDRRPaeTPPFEEVKQQIRQELFQQALEAWLEELRKKA 141
prsA PRK00059
peptidylprolyl isomerase; Provisional
 1-271 6.09e-35

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 128.68  E-value: 6.09e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124   1 MKKKKLFLGTIISCVvLALSACGSS---------DNVVTSKVGN--ITEKELSKE---------LKQKYGES-------- 52
Cdd:PRK00059   1 MKSIKKLVASLLVGV-FIFSAVGCNmiektpeaiAKSTVATVNGekITRGDLDKDpkmqqvleqLKQQYGDNyekneqvk 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  53 ---------TLYQMVLSKALLDKYK-----VSDEEAKKQVEE-------AKDKMGDNFKSTLEQVGLkNEDELKEKMKPE 111
Cdd:PRK00059  80 eqikqqkeqILDSLITEKVLLQKAKelkliPSEEELNKEVDKkineikkQFNNDEEQFEEALKATGF-TEETFKEYLKNQ 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 112 IAFEKAIK-----ATVTEKDVKDNY----------KPEMKVSHILVKDEKTAKEVKEKVNNGEDFAALAKQYSEDTGSKE 176
Cdd:PRK00059 159 IIIEKVINevvkdVKVTDKDAQKYYnenkskftekPNTMHLAHILVKTEDEAKKVKKRLDKGEDFAKVAKEVSQDPGSKD 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 177 QGGEItGFAP---GQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKE--LKPFDEVKDSIRKDIEQQRLQDTTgk 251
Cdd:PRK00059 239 KGGDL-GDVPysdSGYDKEFMDGAKALKEGEISAPVKTQFGYHIIKAIKKKEypVKPFDSVKEDIKKQLLQEKQSEVF-- 315

                        330       340
                 ....*....|....*....|
gi 446650124 252 wkQQVVNELLKDADIKVNDK 271
Cdd:PRK00059 316 --KKKIEEWKKALKVKKYEK 333
prsA PRK01326
foldase protein PrsA; Reviewed
 2-277 9.02e-31

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 116.84  E-value: 9.02e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124   2 KKKKLFLGTIISCVVLALSACGSSD---NVVTSKVGNITEKELSKELKQ-KYGESTLYQMVLSKALLDKY--KVSDEEAK 75
Cdd:PRK01326   1 MKKKLIAGAVTLLSVATLAACSKTNentKVISMKGDTITVSDFYNQVKNnPSAQQAMLNLTISRVFEKQYgdKVSDKEVE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  76 KQVEEAKDKMGDNFKSTLEQVGLKNED---ELKEKMKPEIAFEKAIKATVTEKDVK---DNYKPEMKVSHILVKDEKTAK 149
Cdd:PRK01326  81 KAYAKTAKQYGASFSRALAQAGLTPETykaQIRTSKLVEYAVKEAAKKELTDEAYKkayEEYTPEVTAQIIRLDNEDKAK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 150 EVKEKVN-NGEDFAALAKqysEDTGSKEQGGEITGFAPGQTV-KEFEEAAYKLDAGQVSEPVK----TTYG--YHIIKVT 221
Cdd:PRK01326 161 SVLEEAKaEGADFAQIAK---ENTTTKEKKGEYKFDSGSTNVpEQVKKAAFALDEDGVSDVISvldpTAYQskYYIVKVT 237

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446650124 222 DKKELKP-FDEVKDSIRKDIEQQRLQDTTgkWKQQVVNELLKDADIKVNDKEFKNTF 277
Cdd:PRK01326 238 KKTEKKSdWKDYKKRLKAIILAQKQNDSN--FQNKVIAKALDKANVKIKDKAFANIL 292
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 136-224 7.29e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 101.29  E-value: 7.29e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  136 KVSHILV-------KDEKTAK----EVKEKVNNGEDFAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAGQ 204
Cdd:pfam13616  17 KASHILIsysqavsRTEEEAKakadSLLAALKNGADFAALAKTYSDDPASKNNGGDLGWFTKGQMVKEFEDAVFSLKVGE 96

                          90       100
                  ....*....|....*....|
gi 446650124  205 VSEPVKTTYGYHIIKVTDKK 224
Cdd:pfam13616  97 ISGVVKTQFGFHIIKVTDKK 116
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 139-222 1.30e-25

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 97.37  E-value: 1.30e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  139 HILVK-DEKT----------AKEVKEKVNNGED-FAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAGQVS 206
Cdd:pfam00639   1 HILIKtPEASerdraeakakAEEILEQLKSGEDsFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKPGEIS 80

                          90
                  ....*....|....*.
gi 446650124  207 EPVKTTYGYHIIKVTD 222
Cdd:pfam00639  81 GPVETRFGFHIIKLTD 96
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 61-256 4.15e-20

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 89.68  E-value: 4.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  61 KALLDKYKVSDEEAKKQVEEAKDkmgdNFKSTlEQV-----GLKNEDELKekmkpeiafekaiKATVTEKDVKDNYK--- 132
Cdd:PRK10788 201 NALAAKQTVTDEEIKSYYDQNKN----NFMAP-EQFkvsyiKLDAATMQQ-------------KITVSDADIQAYYDqhq 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 133 -----PEMK-VSHILVKDEKTAKEVKEKVNNGEDFAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKlDAGQVS 206
Cdd:PRK10788 263 dqftqPERKrYSIIQTKTEAEAKAVLDELKKGADFATLAKEKSTDIISARNGGDLGWLEPATTPDELKNAGLK-EKGQLS 341

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446650124 207 EPVKTTYGYHIIKVTDKK--ELKPFDEVKDSIRKDIEQQRLQDTTGKWKQQV 256
Cdd:PRK10788 342 GVIKSSVGFLIVRLDDIQpaKVKPLSEVRDDIAAKVKQEKALDAYYALQQKV 393
PRK12450 PRK12450
foldase protein PrsA; Reviewed
 2-275 1.57e-19

foldase protein PrsA; Reviewed


Pssm-ID: 138982 [Multi-domain]  Cd Length: 309  Bit Score: 86.30  E-value: 1.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124   2 KKKKLFLGTIISCVVLALSACGSSDN---VVTSKVGNITEKELSKELKQ-KYGESTLYQMVLSKALLDKY--KVSDEEAK 75
Cdd:PRK12450   3 QMNKLITGVVTLATVVTLSACQSSHNntkLVSMKGDTITVSDFYNETKNtELAQKAMLSLVISRVFETQYanKVSDKEVE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  76 KQVEEAKDKMGDNFKSTLEQVGLKNED---ELKEKMKPEIAF-EKAIKATVTEKDVK---DNYKPEMKVSHILVKDEKTA 148
Cdd:PRK12450  83 KAYKQTADQYGTSFKTVLAQSGLTPETykkQIRLTKLVEYAVkEQAKNETISKKDYRqayDAYTPTMTAEIMQFEKEEDA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 149 KEVKEKVN-NGEDFAALAKqysEDTGSKEQGGEITgFAPGQTV--KEFEEAAYKLDAGQVSE------PVKTTYGYHIIK 219
Cdd:PRK12450 163 KAALEAVKaEGADFAAIAK---EKTIAADKKTTYT-FDSGETTlpAEVVRAASGLKEGNRSEiitaldPATSKRTYHIIK 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446650124 220 VTDKKELKP-FDEVKDSIRKDIEQQRLQDTtgKWKQQVVNELLKDADIKVNDKEFKN 275
Cdd:PRK12450 239 VTKKATKKAdWKAYQKRLKDIIVTGKLKDP--DFQNKVIAKALDKANVKIKDKAFAN 293
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 136-219 6.87e-14

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 66.59  E-value: 6.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 136 KVSHILVK--------DEKTAKEV--------------KEKVNNGE-DFAALAKQYSeDTGSKEQGGEITGFAPGQTVKE 192
Cdd:PTZ00356   7 RAAHLLIKhtgsrnpvSRRTGKPVtrskeeaikelakwREQIVSGEkTFEEIARQRS-DCGSAAKGGDLGFFGRGQMQKP 85

                         90       100
                 ....*....|....*....|....*..
gi 446650124 193 FEEAAYKLDAGQVSEPVKTTYGYHIIK 219
Cdd:PTZ00356  86 FEDAAFALKVGEISDIVHTDSGVHIIL 112
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 139-224 3.34e-13

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 64.27  E-value: 3.34e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 139 HILVKDEKTAKEVKEKVNNGEDFAALAKQYSEdTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHII 218
Cdd:PRK15441   9 HILVKEEKLALDLLEQIKNGADFGKLAKKHSI-CPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHII 87


                 ....*.
gi 446650124 219 KVTDKK 224
Cdd:PRK15441  88 KVLYRN 93
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 134-233 1.20e-12

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 67.46  E-value: 1.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 134 EMKVSHILVK-------DEKTAK--EVKEKVNNGE-DFAALAKQYSEDTGSKEQGGEITGFAPGQTVKEFEEAAYKLDAG 203
Cdd:PRK10770 266 EVHARHILLKpspimtdEQARAKleQIAADIKSGKtTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALMRLNKG 345

                         90       100       110
                 ....*....|....*....|....*....|
gi 446650124 204 QVSEPVKTTYGYHIIKVTDKKELKPFDEVK 233
Cdd:PRK10770 346 QISAPVHSSFGWHLIELLDTRQVDKTDAAQ 375
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
122-234 9.28e-12

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 60.92  E-value: 9.28e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124  122 VTEKDVKDNY--------KPEMKVSHILVKDEKTAKEVKEKVNNGEDFAALAKQYSEDTGSKEQGGEITgfAPGQTVKEF 193
Cdd:pfam13145   1 VTEEELKAYYeenkdefsTPEGRLLEILVFKDQVAADAALALLKAGALEDFAALAKGEGIKAATLDIVE--SAELLPEEL 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 446650124  194 EEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKE--LKPFDEVKD 234
Cdd:pfam13145  79 AKAAFALKPGEVSGPIKTGNGYYVVRVTEIKPaqPLPFEEAKD 121
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 133-222 9.04e-07

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 49.74  E-value: 9.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650124 133 PEMKVSHILV------------KDEKTAKEVKEKVNNGEDFAALAKQYSEDTGSKeQGGEItGFAPGQTVKE-FEEAAYK 199
Cdd:PRK10770 154 TELNLSHILIplpenptqdqvdEAESQARSIVDQARNGADFGKLAIAYSADQQAL-KGGQM-GWGRIQELPGlFAQALST 231

                         90       100
                 ....*....|....*....|...
gi 446650124 200 LDAGQVSEPVKTTYGYHIIKVTD 222
Cdd:PRK10770 232 AKKGDIVGPIRSGVGFHILKVND 254
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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