|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
1-255 |
2.70e-164 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 454.61 E-value: 2.70e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 1 MKKKLGLLAMVVALMAITAGCSEVNQPITPKSTGIWNEYFVYPLSQLITYFANLFGSNYGLAIVVTTLIIRFALLPLMIK 80
Cdd:PRK02944 1 MKKKLGLLAMVVALMAILAGCSEVNQPITPKSTGFWNEYFVYPLSQLITYFANLFGSNYGLAIIVVTLLIRLLILPLMIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 81 QTKSTKAMQALQPEMVKLKEKYSSKDQATQQKLQQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTF 160
Cdd:PRK02944 81 QTKSTKAMQALQPEMQKLKEKYSSKDQATQQKLQQEMMQLFQKNGVNPLAGCLPIFIQMPILIAFYHAIMRTSEISKHSF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 161 LWFDLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMYLI 240
Cdd:PRK02944 161 LWFDLGQADPYYILPIVAGITTFIQQKLMMAGTAGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFMIAQTYLI 240
|
250
....*....|....*
gi 446650402 241 KGPEIKASKAGGSSK 255
Cdd:PRK02944 241 KGPEIKASKAGGSKK 255
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
36-241 |
1.09e-89 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 263.90 E-value: 1.09e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 36 WNEYFVYPLSQLITYFANLFGsNYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYssKDqaTQQKLQQ 115
Cdd:COG0706 5 WFGFIAKPLFWLLNFLHSLVG-NWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKY--KD--DPQKLQQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 116 EMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTFLWF-DLGQADPYYI-LPVVAAITTFIQQKLAMAgt 193
Cdd:COG0706 80 EMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPFLGIpDLSAPDPYYIfLPILMGVTMFLQQKLNPA-- 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446650402 194 AGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMYLIK 241
Cdd:COG0706 158 PAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIIN 205
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
60-241 |
4.57e-87 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 256.15 E-value: 4.57e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 60 GLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKdqatQQKLQQEMMQLYQKNGVNPLAGCLPIFVQM 139
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDD----KQKLQQEMMKLYKEHGVNPLGGCLPLLIQM 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 140 PILFAFYHAIMRTSEISKHTFLWF--DLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIFAIN 217
Cdd:cd20070 77 PIFIALYQVLRNSIELRGAPFLWWilDLSAPDPYYILPILMGVTMFLQQKLTPTPTDDQAPQQKMMMYFMPVMFTFIFLS 156
|
170 180
....*....|....*....|....
gi 446650402 218 FPAALSLYWVVGNIFGIAQMYLIK 241
Cdd:cd20070 157 FPSGLVLYWLVSNLFSIIQQLIIN 180
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
58-240 |
2.01e-82 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 244.31 E-value: 2.01e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 58 NYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKdqatQQKLQQEMMQLYQKNGVNPLAGCLPIFV 137
Cdd:TIGR03592 1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKED----PQKLQQEMMKLYKEEGVNPLGGCLPLLI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 138 QMPILFAFYHAIMRTSEISKHTFLW-FDLGQADPYYILPVVAAITTFIQQKLAMAGTAgQNPQMAMMLWLMPIMILIFAI 216
Cdd:TIGR03592 77 QMPIFIALYQVLLRSIELRHAPFLWiIDLSSPDPYYILPILMGVTMFLQQKLSPKGPP-DPAQQKMMMYFMPLMFLFFFL 155
|
170 180
....*....|....*....|....
gi 446650402 217 NFPAALSLYWVVGNIFGIAQMYLI 240
Cdd:TIGR03592 156 SFPAGLVLYWVVSNLFTIIQQLII 179
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
59-241 |
3.01e-78 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 234.29 E-value: 3.01e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 59 YGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKDQatqqKLQQEMMQLYQKNGVNPLAGCLPIFVQ 138
Cdd:pfam02096 1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQ----KLQQEMMKLYKKEGVNPLGGCLPMLIQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 139 MPILFAFYHAIMRTSEISK-HTFLWF-DLGQADP-----YYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMI 211
Cdd:pfam02096 77 MPIFIALYRVLRNSIELRHaPFFLWIaDLSAPDPisilhYYILPILMGVTMFLQQKLTPAPQDQPPQMKMMMLYFMPLMF 156
|
170 180 190
....*....|....*....|....*....|
gi 446650402 212 LIFAINFPAALSLYWVVGNIFGIAQMYLIK 241
Cdd:pfam02096 157 LFFFLNFPAGLVLYWVVSNLLSIGQQLIIN 186
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
1-255 |
2.70e-164 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 454.61 E-value: 2.70e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 1 MKKKLGLLAMVVALMAITAGCSEVNQPITPKSTGIWNEYFVYPLSQLITYFANLFGSNYGLAIVVTTLIIRFALLPLMIK 80
Cdd:PRK02944 1 MKKKLGLLAMVVALMAILAGCSEVNQPITPKSTGFWNEYFVYPLSQLITYFANLFGSNYGLAIIVVTLLIRLLILPLMIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 81 QTKSTKAMQALQPEMVKLKEKYSSKDQATQQKLQQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTF 160
Cdd:PRK02944 81 QTKSTKAMQALQPEMQKLKEKYSSKDQATQQKLQQEMMQLFQKNGVNPLAGCLPIFIQMPILIAFYHAIMRTSEISKHSF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 161 LWFDLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMYLI 240
Cdd:PRK02944 161 LWFDLGQADPYYILPIVAGITTFIQQKLMMAGTAGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFMIAQTYLI 240
|
250
....*....|....*
gi 446650402 241 KGPEIKASKAGGSSK 255
Cdd:PRK02944 241 KGPEIKASKAGGSKK 255
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
36-241 |
1.09e-89 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 263.90 E-value: 1.09e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 36 WNEYFVYPLSQLITYFANLFGsNYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYssKDqaTQQKLQQ 115
Cdd:COG0706 5 WFGFIAKPLFWLLNFLHSLVG-NWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKY--KD--DPQKLQQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 116 EMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTFLWF-DLGQADPYYI-LPVVAAITTFIQQKLAMAgt 193
Cdd:COG0706 80 EMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPFLGIpDLSAPDPYYIfLPILMGVTMFLQQKLNPA-- 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446650402 194 AGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMYLIK 241
Cdd:COG0706 158 PAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIIN 205
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
60-241 |
4.57e-87 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 256.15 E-value: 4.57e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 60 GLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKdqatQQKLQQEMMQLYQKNGVNPLAGCLPIFVQM 139
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDD----KQKLQQEMMKLYKEHGVNPLGGCLPLLIQM 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 140 PILFAFYHAIMRTSEISKHTFLWF--DLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIFAIN 217
Cdd:cd20070 77 PIFIALYQVLRNSIELRGAPFLWWilDLSAPDPYYILPILMGVTMFLQQKLTPTPTDDQAPQQKMMMYFMPVMFTFIFLS 156
|
170 180
....*....|....*....|....
gi 446650402 218 FPAALSLYWVVGNIFGIAQMYLIK 241
Cdd:cd20070 157 FPSGLVLYWLVSNLFSIIQQLIIN 180
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
58-240 |
2.01e-82 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 244.31 E-value: 2.01e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 58 NYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKdqatQQKLQQEMMQLYQKNGVNPLAGCLPIFV 137
Cdd:TIGR03592 1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKED----PQKLQQEMMKLYKEEGVNPLGGCLPLLI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 138 QMPILFAFYHAIMRTSEISKHTFLW-FDLGQADPYYILPVVAAITTFIQQKLAMAGTAgQNPQMAMMLWLMPIMILIFAI 216
Cdd:TIGR03592 77 QMPIFIALYQVLLRSIELRHAPFLWiIDLSSPDPYYILPILMGVTMFLQQKLSPKGPP-DPAQQKMMMYFMPLMFLFFFL 155
|
170 180
....*....|....*....|....
gi 446650402 217 NFPAALSLYWVVGNIFGIAQMYLI 240
Cdd:TIGR03592 156 SFPAGLVLYWVVSNLFTIIQQLII 179
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
59-241 |
3.01e-78 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 234.29 E-value: 3.01e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 59 YGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKDQatqqKLQQEMMQLYQKNGVNPLAGCLPIFVQ 138
Cdd:pfam02096 1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQ----KLQQEMMKLYKKEGVNPLGGCLPMLIQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 139 MPILFAFYHAIMRTSEISK-HTFLWF-DLGQADP-----YYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMI 211
Cdd:pfam02096 77 MPIFIALYRVLRNSIELRHaPFFLWIaDLSAPDPisilhYYILPILMGVTMFLQQKLTPAPQDQPPQMKMMMLYFMPLMF 156
|
170 180 190
....*....|....*....|....*....|
gi 446650402 212 LIFAINFPAALSLYWVVGNIFGIAQMYLIK 241
Cdd:pfam02096 157 LFFFLNFPAGLVLYWVVSNLLSIGQQLIIN 186
|
|
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
1-241 |
2.03e-73 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 224.25 E-value: 2.03e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 1 MKKKLGLLAMVVALMAITAGCSEVNQPITPKSTGIWNEYFVYPLSQLITYFANLFGSNYGLAIVVTTLIIRFALLPLMIK 80
Cdd:PRK01622 2 LKSYRAVLVSLSLLLVLVLSGCSNAAPIDAHSDGFFDHYFVYPFSFLIQFVAHHIGGSYGIAIIIVTLIIRSLMIPLAVS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 81 QTKSTKAMQA----LQPEMVKLKEKYS-SKDQATQQKLQQEMMQLYQKNGVNPLA-GCLPIFVQMPILFAFYHAIMRTSE 154
Cdd:PRK01622 82 QYKSQRGMQEkmavMKPELDKIQAKLKvTKDLEKQKEYQKEMMELYKSGNINPLAmGCLPLLIQMPILSAFYYAIRRTEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 155 ISKHTFLWFDLGQADpyYILPVVAAITTFIQQKLAMAgtAGQNP----QMAMMLWLMPIMILIFAINFPAALSLYWVVGN 230
Cdd:PRK01622 162 IASHSFLWFNLGHAD--HILPIIAGLTYFIQMKVSQS--NGTSPeqvqMLKIQGIMMPAMILFMSFAAPSALVLYWITGG 237
|
250
....*....|.
gi 446650402 231 IFGIAQMYLIK 241
Cdd:PRK01622 238 LFLMGQTIVLR 248
|
|
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
36-241 |
4.97e-65 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 210.88 E-value: 4.97e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 36 WNEYFVYPLSQLITYFANLFGsNYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYssKDQAtqQKLQQ 115
Cdd:PRK01318 301 WLWFITKPLFWLLDFLHSFVG-NWGWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKY--KDDP--QKMQQ 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 116 EMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEIsKHT--FLWF-DLGQADPYYIL-----PVVAAITTFIQQK 187
Cdd:PRK01318 376 EMMELYKKEKVNPLGGCLPILIQIPIFFALYKVLLVSIEL-RHApfIGWIhDLSAPDPYFILhigllPILMGITMFLQQK 454
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446650402 188 LAMagTAGQNPQMAMMLWlMPIMILIFAINFPAALSLYWVVGNIFGIAQMYLIK 241
Cdd:PRK01318 455 LNP--TPTDPMQAKIMKF-MPLIFTFFFLSFPAGLVLYWIVNNLLTIIQQYLIN 505
|
|
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
56-241 |
6.29e-61 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 191.49 E-value: 6.29e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 56 GSNYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKdqatQQKLQQEMMQLYQKNGVNPLAGCLPI 135
Cdd:PRK00145 28 NFSYGIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKYKND----PQKLQQEMMKLYKEKGVNPLGGCLPL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 136 FVQMPILFAFYHAIMRTSEISKHTFLWF-DLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIF 214
Cdd:PRK00145 104 LIQWPILIALYYVFNNLTGINGVSFLWIkDLAKPDITWILPILSGATTYLSGYLMTKADSSQAGQMKTMNIGMSIFMGVM 183
|
170 180
....*....|....*....|....*..
gi 446650402 215 AINFPAALSLYWVVGNIFGIAQMYLIK 241
Cdd:PRK00145 184 SWKFKSALVLYWVIGNLIQIIQTYFIK 210
|
|
| 5TM_YidC_Oxa1_Alb3 |
cd19751 |
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ... |
60-241 |
2.78e-56 |
|
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410992 [Multi-domain] Cd Length: 189 Bit Score: 178.52 E-value: 2.78e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 60 GLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSK--DQATQQKLQQEMMQLYQKNGVNPLAGCLPIFV 137
Cdd:cd19751 1 GLSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYKEKasKDKVQQEMQKEMLGLYKKHGVNPMAGCLPLFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 138 QMPILFAFYHAIMRTSEISKHTFLWF-DLGQADPYYILPVVAAITTFIQQKLAMA-GTAGQ--NPQMAMMLWLMPIMILI 213
Cdd:cd19751 81 QLPIFMAFYFAIMRTEEIRYHTFLWFfDLGQPDYLYILPFVAGITTYFQFKMTMShQQQMQmmQMQMKVMLYVMPVMIII 160
|
170 180
....*....|....*....|....*...
gi 446650402 214 FAINFPAALSLYWVVGNIFGIAQMYLIK 241
Cdd:cd19751 161 AGLSFPSALSLYWIISNLFMIIQTYFIV 188
|
|
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
2-241 |
1.80e-51 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 169.91 E-value: 1.80e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 2 KKKLGLLAMVVALMAITAGCseVNQPITPKSTGIWNEYFVYPLSQLITYFANLFGSNYGLAIVVTTLIIRFALLPLMIKQ 81
Cdd:PRK02463 5 LKRILFSGLALSMLLTLTGC--VGRDKHGNPTGFIWNFLGAPMSYFIDYFANNLGLGFGLAIIIVTIIVRLIILPLGLYQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 82 T-KST---KAMQALQPEMVKLKEKYSsKDQATQQKL--QQEMMQLYQKNGVNPLA--GCLPIFVQMPILFAFYHAIMRTS 153
Cdd:PRK02463 83 SwKATyqsEKMAYLKPVFEPINERLK-NATTQEEKMaaQTELMAAQRENGISMLGgiGCLPLLIQMPFFSALYFAAQYTK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 154 EISKHTFLWFDLGQadPYYILPVVAAITTFIQQKLAMAGTA-GQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIF 232
Cdd:PRK02463 162 GVSTSTFLGIDLGS--PSLVLTAIIGVLYFFQSWLSMMGVPeEQREQMKAMMYMMPIMMVVFSFSSPAGVGLYWLVGGFF 239
|
250
....*....|...
gi 446650402 233 GIAQ----MYLIK 241
Cdd:PRK02463 240 SIIQqlitTYILK 252
|
|
| 5TM_Oxa1-like |
cd20069 |
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ... |
61-243 |
1.31e-48 |
|
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410993 [Multi-domain] Cd Length: 201 Bit Score: 159.23 E-value: 1.31e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 61 LAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYS----SKDQATQQKLQQEMMQLYQKNGVNPLAGCLPIF 136
Cdd:cd20069 6 ATIAATTVALRLLLLPLVIKSQRNAARMANLQPELQKLQEKLKearaSGDQLEAAEARKELKELMKKHNVNPLKSLLLPL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 137 VQMPILFAFYHAIMRTSEISKHTF-----LWF-DLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLM--- 207
Cdd:cd20069 86 VQAPVFISFFFALRKMANLPVPSFktgglLWFtDLTVPDPYYILPILTSLTFLATIELGAETGTSGSPQSKTMKNVFrgl 165
|
170 180 190
....*....|....*....|....*....|....*.
gi 446650402 208 PIMILIFAINFPAALSLYWVVGNIFGIAQMYLIKGP 243
Cdd:cd20069 166 PVLMIPFTANFPSAVFLYWITSNLFSLAQNLLLRIP 201
|
|
| PRK01315 |
PRK01315 |
putative inner membrane protein translocase component YidC; Provisional |
56-250 |
2.04e-38 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234941 Cd Length: 329 Bit Score: 136.41 E-value: 2.04e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 56 GSNYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKdqatQQKLQQEMMQLYQKNGVNPLAGCLPI 135
Cdd:PRK01315 39 GLTWVLSIVGLVIVIRALLIPLFVKQIKSQRNMQEIQPKMKKIQEKYKGD----RERMSQEMMKLYKETGTNPLSSCLPL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 136 FVQMPILFAFYHAImrTSEISKHTF-------LWFDLGQADPY----------------YILPVVAAI-------TTFIQ 185
Cdd:PRK01315 115 LLQMPIFFALYRVL--DSAASRGDGigpinppLLESFRHAHIFgaplaatflqalnagnTAVQVVAAVliilmsaSQFIT 192
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446650402 186 QKLAMAG----TAGQNPQMA---MMLWLMPIMILIFAINFPAALSLYWVVGNIFGIA-QMYLIKGPEIKASKA 250
Cdd:PRK01315 193 QLQLMTKnmppEAKTGPMAQqqkMLLYLFPLMFLVSGIAFPVGVLFYWLTSNVWTMGqQFYVIRNNPTPGSPA 265
|
|
| PRK03449 |
PRK03449 |
putative inner membrane protein translocase component YidC; Provisional |
42-242 |
5.03e-30 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 179580 Cd Length: 304 Bit Score: 114.01 E-value: 5.03e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 42 YPLSQLITYFANLF--------GSNYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSsKDQatqQKL 113
Cdd:PRK03449 7 YPVSAILWFWHKLFsfvlgpdnGFAWALSVMFLVFTLRALLYKPFVRQIRTTRKMQELQPQIKALQKKYG-NDR---QKM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 114 QQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIM---RTSEISKHTFLWFDLGQADPYYI----------------- 173
Cdd:PRK03449 83 ALEMQKLQKEHGFNPILGCLPMLAQIPVFLGLFHVLRsfnRTGTGFGQLGMSVEENRNTPNYVfsaedvqsfldarlfga 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 174 ------------------------------LPVVAAITTFIQQKLAMA---GTAGQNPQMAMM----LWLMPIMILIFAI 216
Cdd:PRK03449 163 plsayitmprsgldafvdftrtniilvgvpLMIIAGVATHFNSRASVArqsAEAAANPQTAMMnklaLWVFPLGVLVGGP 242
|
250 260
....*....|....*....|....*.
gi 446650402 217 NFPAALSLYWVVGNIFGIAQMYLIKG 242
Cdd:PRK03449 243 FLPLAILLYWVSNNIWTFGQQHYVFG 268
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
25-240 |
1.43e-29 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 113.57 E-value: 1.43e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 25 NQPITPKSTGIWNE-----YFVYPLSQLITYFANLFGSN--YG----LAIVVTTLIIRFALLPLMIKQTKSTKAMQALQP 93
Cdd:PRK02201 88 TGPYNPITSWTWKYgpfygLFVYPIAQIILSIMASQSLSelYGwstiLAIIVVVLIIRLISFLITFKSTFNQEKQEELQG 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 94 EMVKLKEKYS--SKDQATQQKLQQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTFLWFDLGQAD-- 169
Cdd:PRK02201 168 KKAKIDAKYKdyKKDKQMKQRKQQEIQELYKKHNISPFSPFVQMFVTLPIFIAVYRVVQSLPSIKVTTWLGIDLSATSwq 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 170 -------PYYILPVVAAITTFIQQKL----------AMAGTAGQNPQMA---MMLWLMPIMILIFAINFPAALSLYWVVG 229
Cdd:PRK02201 248 eifagnwIYLPILIIVVPVQALSQLLpqilnkkknkERTLNVKEKEALKkqnKTQNIISIVFIFFGVIFAAGVQIYWIIG 327
|
250
....*....|.
gi 446650402 230 NIFGIAQMYLI 240
Cdd:PRK02201 328 GIWTILQTLGI 338
|
|
| PRK01001 |
PRK01001 |
putative inner membrane protein translocase component YidC; Provisional |
47-238 |
3.27e-26 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234887 [Multi-domain] Cd Length: 795 Bit Score: 106.81 E-value: 3.27e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 47 LITYFANLFGSnYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSsKDQatqQKLQQEMMQLYQKNGV 126
Cdd:PRK01001 565 IMKFFKFLTGS-WGISIILLTVFLKLLLYPLNAWSIRSMRRMQKLSPYIQEIQQKYK-KEP---KRAQMEIMALYKTNKV 639
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 127 NPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTFL--WFD-LGQAD--------------PYYILPVVAAITTFIQQKLA 189
Cdd:PRK01001 640 NPITGCLPLLIQLPFLIAMFDLLKSSFLLRGASFIpgWIDnLTAPDvlfswetpiwfignEFHLLPILLGVVMFAQQKIS 719
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446650402 190 MAGTAG----QNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMY 238
Cdd:PRK01001 720 SLKRKGpvtdQQRQQEAMGTMMALLFTFMFYNFPSGLNIYWLSSMLLGVIQQW 772
|
|
| PRK02654 |
PRK02654 |
putative inner membrane protein translocase component YidC; Provisional |
58-153 |
1.88e-25 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235058 Cd Length: 375 Bit Score: 102.75 E-value: 1.88e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 58 NYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVK----LKEKYSSKdqatQQKLQQEMMQLYQKNGvNPLAGCL 133
Cdd:PRK02654 26 SYGLAIVALTLVIRFALYPLSAGSIRNMRRMKIAQPVMQKrqaeIQERYKND----PQKQQEEMGKLMKEFG-NPLAGCL 100
|
90 100
....*....|....*....|
gi 446650402 134 PIFVQMPILFAFYhAIMRTS 153
Cdd:PRK02654 101 PLLVQMPILFALF-ATLRGS 119
|
|
| PRK00247 |
PRK00247 |
putative inner membrane protein translocase component YidC; Validated |
38-240 |
1.63e-18 |
|
putative inner membrane protein translocase component YidC; Validated
Pssm-ID: 178945 [Multi-domain] Cd Length: 429 Bit Score: 84.13 E-value: 1.63e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 38 EYFVYPLSQLIT----YFANLFGSNYGLA-------IVVTtliIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSK- 105
Cdd:PRK00247 3 DIFIYPVSGVMKlwhlLLHNVLGLDDSLAwfaslfgLVIT---VRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKGKt 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 106 DQATQQKLQQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMR-------------------TSE------------ 154
Cdd:PRK00247 80 DEASIRELQQKQKDLNKEYGYNPLAGCVPALIQIPVFLGLYQVLLRmarpegglenpvhqpigflTSEevesflqgrvfn 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446650402 155 --------ISKHTFLWFDLGQADPY-YILP--VVAAITTFIQQKLAMAGT-----------AGQNPQMAMMLWLMPIMIL 212
Cdd:PRK00247 160 vplpayvsMPAEQLAYLGTTQATVLaFVLPlfIAAAVFTAINMAMSTYRSfqtndhdsgfaVGMLKFLIVMAILAPIFPL 239
|
250 260 270
....*....|....*....|....*....|...
gi 446650402 213 IFAIN--FPAALSLYWVVGNIFGIAQ---MYLI 240
Cdd:PRK00247 240 SLGLTgpFPTAIALYWVANNLWTLIQniiMYLI 272
|
|
| |
