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MULTISPECIES: penicillin-binding protein 2 [Bacillus]
Protein Classification
peptidoglycan D,D-transpeptidase FtsI family protein ( domain architecture ID 11433609 )
peptidoglycan D,D-transpeptidase FtsI (penicillin-binding protein (PBP) 2) family protein is a membrane-associated enzyme that is most likely involved in the synthesis of cross-linked peptidoglycan
List of domain hits
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
1-693
7.71e-149
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 445.04
E-value: 7.71e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 1 MK K qe KK SG R VVPL RL NI LFL C V F LLF SGI V IQ L GKV Q IFD G ET Y KNEV E KRENT TV GLSV PRG K I F DR E GN PVVD N KSL 80
Cdd:COG0768 1 MK R -- KK EK R LFRR RL LL LFL L V L LLF LLL V GR L FYL Q VVE G DE Y AELA E ENRIR TV PIPA PRG L I Y DR N GN VLAT N VPV 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 81 RTITYTKVKGVKQ EE I lks A RQ LA DIIEMPQ E DIA K L tetdkkdfwmqlnpeltqdlvskkeidkfrdkditgkeldkki 160
Cdd:COG0768 79 YSLYADPEEVKDP EE T --- A EK LA KLLGLDP E ELR K K ------------------------------------------- 112
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 161 ed LK R K R vtdknlqeltakdievlaikskmts G F qma P QII K KDV S EQ E Y A V I se NLA KLPGV DASVDWE R I Y VNDG L FR 240
Cdd:COG0768 113 -- LK K K S ------------------------- R F --- P VYL K RNL S PE E A A R I -- RAL KLPGV YVEAEYK R Y Y PYGE L AA 160
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 241 S VLG N V SNA deglprerldyylvrdy SRN D RV GKS YI E QQ YED V L H GT KKEV R SIA D KQ G NTM R T - ETVSEGKS GK N L T L 319
Cdd:COG0768 161 H VLG Y V GEI ----------------- NGG D GI GKS GL E KA YED L L R GT PGKR R VEV D AR G RVI R D l GEEKPPVP GK D L V L 223
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 320 TID ME LQK KV EE SIE K ILKQ YK G sesml DRAF VV M M N PK N G QV L S MA GK ------ KL V EKDG kmev E DYALGTLTSS YE L 393
Cdd:COG0768 224 TID SD LQK IA EE ALK K AVEE YK A ----- KSGA VV V M D PK T G EI L A MA SY psfdpn LF V GGPD ---- E PLRNRAVQGT YE P 294
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 394 GST V K GA T VLTGF E TNA ITP G T H F YD - APMKFK G TK e KKS W K -- NF G DIDDLR AL QV SSNV YMFNI AL KI a G V D yvknss 470
Cdd:COG0768 295 GST F K PF T AAAAL E EGV ITP D T T F DC p GYYRVG G RT - IRD W D rg GH G TLTLTE AL AK SSNV GFYKL AL RL - G I D ------ 366
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 471 ldikqeyfd K MRY Y FRQ FGLG VQ TGIDLP N E TA G QIGRKDN - Q PG FLLDY SIGQ YDTY TPLQLAQ YIST IANGG YRM KP Q 549
Cdd:COG0768 367 --------- K LYD Y LKK FGLG QK TGIDLP G E AS G LLPSPKR w Y PG ETATM SIGQ GLSV TPLQLAQ AYAA IANGG VLV KP H 437
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 550 I V Q EI R eqtvqk D EV G K VV QS i EP V VL N R I d MKQ E YINQ V K EG FRK V FQ E GD GT GV RA f QKAP Y KP AGKTGTAQ T V ygge 629
Cdd:COG0768 438 L V K EI V ------ D PD G E VV KE - EP E VL R R V - ISP E TAET V R EG MEG V VN E PG GT AR RA - AIPG Y RV AGKTGTAQ V V ---- 504
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446666441 630 n DIG RNEKGDR R ec YNLTLA G Y AP Y D D P EV A FS VVV PWVENDKS G -- INSDIGK E VLD AY FD L KNK 693
Cdd:COG0768 505 - DIG NGGYYKG R -- HIASFV G F AP A D N P RY A VA VVV ENPGGGAY G gt VAAPVFR E IME AY LR L LGP 567
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
1-693
7.71e-149
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 445.04
E-value: 7.71e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 1 MK K qe KK SG R VVPL RL NI LFL C V F LLF SGI V IQ L GKV Q IFD G ET Y KNEV E KRENT TV GLSV PRG K I F DR E GN PVVD N KSL 80
Cdd:COG0768 1 MK R -- KK EK R LFRR RL LL LFL L V L LLF LLL V GR L FYL Q VVE G DE Y AELA E ENRIR TV PIPA PRG L I Y DR N GN VLAT N VPV 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 81 RTITYTKVKGVKQ EE I lks A RQ LA DIIEMPQ E DIA K L tetdkkdfwmqlnpeltqdlvskkeidkfrdkditgkeldkki 160
Cdd:COG0768 79 YSLYADPEEVKDP EE T --- A EK LA KLLGLDP E ELR K K ------------------------------------------- 112
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 161 ed LK R K R vtdknlqeltakdievlaikskmts G F qma P QII K KDV S EQ E Y A V I se NLA KLPGV DASVDWE R I Y VNDG L FR 240
Cdd:COG0768 113 -- LK K K S ------------------------- R F --- P VYL K RNL S PE E A A R I -- RAL KLPGV YVEAEYK R Y Y PYGE L AA 160
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 241 S VLG N V SNA deglprerldyylvrdy SRN D RV GKS YI E QQ YED V L H GT KKEV R SIA D KQ G NTM R T - ETVSEGKS GK N L T L 319
Cdd:COG0768 161 H VLG Y V GEI ----------------- NGG D GI GKS GL E KA YED L L R GT PGKR R VEV D AR G RVI R D l GEEKPPVP GK D L V L 223
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 320 TID ME LQK KV EE SIE K ILKQ YK G sesml DRAF VV M M N PK N G QV L S MA GK ------ KL V EKDG kmev E DYALGTLTSS YE L 393
Cdd:COG0768 224 TID SD LQK IA EE ALK K AVEE YK A ----- KSGA VV V M D PK T G EI L A MA SY psfdpn LF V GGPD ---- E PLRNRAVQGT YE P 294
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 394 GST V K GA T VLTGF E TNA ITP G T H F YD - APMKFK G TK e KKS W K -- NF G DIDDLR AL QV SSNV YMFNI AL KI a G V D yvknss 470
Cdd:COG0768 295 GST F K PF T AAAAL E EGV ITP D T T F DC p GYYRVG G RT - IRD W D rg GH G TLTLTE AL AK SSNV GFYKL AL RL - G I D ------ 366
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 471 ldikqeyfd K MRY Y FRQ FGLG VQ TGIDLP N E TA G QIGRKDN - Q PG FLLDY SIGQ YDTY TPLQLAQ YIST IANGG YRM KP Q 549
Cdd:COG0768 367 --------- K LYD Y LKK FGLG QK TGIDLP G E AS G LLPSPKR w Y PG ETATM SIGQ GLSV TPLQLAQ AYAA IANGG VLV KP H 437
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 550 I V Q EI R eqtvqk D EV G K VV QS i EP V VL N R I d MKQ E YINQ V K EG FRK V FQ E GD GT GV RA f QKAP Y KP AGKTGTAQ T V ygge 629
Cdd:COG0768 438 L V K EI V ------ D PD G E VV KE - EP E VL R R V - ISP E TAET V R EG MEG V VN E PG GT AR RA - AIPG Y RV AGKTGTAQ V V ---- 504
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446666441 630 n DIG RNEKGDR R ec YNLTLA G Y AP Y D D P EV A FS VVV PWVENDKS G -- INSDIGK E VLD AY FD L KNK 693
Cdd:COG0768 505 - DIG NGGYYKG R -- HIASFV G F AP A D N P RY A VA VVV ENPGGGAY G gt VAAPVFR E IME AY LR L LGP 567
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
15-689
2.46e-114
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 356.45
E-value: 2.46e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 15 R LNI L FLC V FL LF SGIVIQ L GKV Q IFD GE T Y KNEV E KRENTT V GLSV PRG K I F DR E G NPVV DN KSLRTITYTKV K GVKQE 94
Cdd:TIGR03423 2 R ALV L GGL V LA LF GVLAAR L FYL Q VIR GE E Y ATLS E DNRIRL V PIPP PRG L I L DR N G VLLA DN RPSFSLEIVPE K VDDLD 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 95 EI L ksa RQ LA DIIEMPQ EDIA K ltetdkkdfwmqlnpeltqdlvskkeidkfrdkditgkeldk KIED LKR K R vtdknlq 174
Cdd:TIGR03423 82 AT L --- DR LA KLLDLDP EDIA R ------------------------------------------ FLKE LKR S R ------- 109
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 175 eltakdievlaikskmts G F Q ma P QII K K D VS E Q E Y A VISE N LAK LPGV DASVDWE R I Y VNDG L FRS VLG N V S -- N ADE g 252
Cdd:TIGR03423 110 ------------------ R F E -- P IPL K S D LT E E E V A RFAV N QYR LPGV EIEARLK R Y Y PYGE L AAH VLG Y V G ei N EED - 168
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 253 lp R ERL DY ylv RD Y SRN D RV GKS Y IE QQ YED V L H G TKKEVRSIADKQ G NTM RT ETVSEGKS GK N L T LTID ME LQ KK vees 332
Cdd:TIGR03423 169 -- L ERL EP --- AN Y AGG D YI GKS G IE KY YED E L R G KPGYREVEVNAR G RVI RT LSRVPPVP GK D L V LTID AR LQ QA ---- 239
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 333 I EK I L KQYK G S esmldraf VV M M N P KN G QV L S M AGK ------ KL V E ---- KD G K M -- EVE D YA L -- GTLTSS Y EL GST V K 398
Cdd:TIGR03423 240 A EK A L GGRR G A -------- VV V M D P RT G EI L A M VST psfdpn LF V D giss KD Y K A ll NDP D RP L ln RAIQGV Y PP GST F K 311
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 399 GATV L TGF E TNA ITP G T HF Y D a P MK F K - G TKEKKS WK -- NF G DI D DLR A LQV S SN VY MFNI AL KI a G V D yvknssldikq 475
Cdd:TIGR03423 312 PVVA L AAL E EGV ITP E T RI Y C - P GY F Q l G GRRFRC WK rg GH G RV D LRK A IEE S CD VY FYQL AL RL - G I D ----------- 378
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 476 eyfd K MRY Y FRQ FG L G VQ TGIDLP N E TA G QIG ------ RKDN QP --- G FL L DY SIGQ - Y DTY TPLQLA QYISTI ANGG YR 545
Cdd:TIGR03423 379 ---- K IAE Y AKR FG F G QK TGIDLP G E KS G LVP srewkr KRFG QP wyp G DT L NV SIGQ g Y VLV TPLQLA VATAAL ANGG KL 454
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 546 M KP QI V QE I REQT vqkdev G K VV QSI EP V VL NRIDMKQ E YINQ V K EG F R K V FQEGD GT GV RA FQKA PYK P AGKTGTAQ T V 625
Cdd:TIGR03423 455 Y KP HL V KS I EDPD ------ G G VV RRT EP E VL RPLPISP E NLDV V R EG M R D V VNGPG GT AR RA RLGL PYK M AGKTGTAQ V V 528
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446666441 626 YGGENDIGRN E KGDR R ECYNLTLAGY APYD D P EV A FS V V vpw VE NDKS G -- INSD I GKEVL DAY FD 689
Cdd:TIGR03423 529 SLKQGEKYDA E QIPE R LRDHALFVAF APYD N P KI A VA V I --- VE HGGG G ss AAAP I ARKIM DAY LL 591
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
350-685
3.18e-71
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 233.85
E-value: 3.18e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 350 AFV V MMN PK N G Q VL S M A GK K lv EK D GKMEVEDYALGTL TS S YE L GST V K GA T V L TGFETNAIT P GTHFY D A P M K FK G T K E 429
Cdd:pfam00905 1 GSA V VLD PK T G E VL A M V GK P -- SY D PNGFIGPLRNRAV TS R YE P GST F K PF T A L AALDNGVLK P DETIF D W P G K QQ G G K S 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 430 KKS W KNFGD - I DD LR - AL QV SSN V YM FNI A L K IA gvdyvknssldikqey F DK M R Y Y FRQ FG L G VQ TGI D LP N E T AG QIG 507
Cdd:pfam00905 79 IGD W NQDQV g I GT LR q AL EY SSN W YM QKL A Q K LG ---------------- A DK L R S Y LKK FG Y G NK TGI G LP G E N AG YLT 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 508 RKDNQ p G FLLDYS IG qy D T Y TPLQ L AQ YIST IANGG YRMK P QI V QE I reqtvqkdevgkv VQSIE P V VLN RIDMKQEYIN 587
Cdd:pfam00905 143 PYWLE - G ATASFG IG -- L T I TPLQ Q AQ AYAA IANGG KLVP P HL V KS I ------------- EDKVD P K VLN KLPISKSTAE 206
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 588 Q VK EGF R K V fq EG DGTG VRAFQKAP YK P AGKTGTAQ TVYGGEN digrnek G DRRECYNLTLA GYAP Y D D P EV AF S V VVPW 667
Cdd:pfam00905 207 K VK DML R L V -- VN DGTG TGTAAVPG YK V AGKTGTAQ VAGPKGG ------- G YYDGAQIGWFV GYAP A D N P KY AF A V LIDD 277
330
....*....|....*....
gi 446666441 668 VENDKS G INSD - I G K EV L D 685
Cdd:pfam00905 278 PKRYYG G KVAA p I F K DI L E 296
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
15-685
2.15e-39
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 154.54
E-value: 2.15e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 15 R LNIL FL CVF LL FSGIVIQ L GKV QI FDGET Y KNEVEKRENTT V GLSVP RG K I F DR E G N P VVD N ksl RTI tytkvkgvkqe 94
Cdd:PRK10795 21 R ALVA FL GIL LL TGVLIAN L YNL QI VRFTD Y QTRSNENRIKL V PIAPS RG I I Y DR N G T P LAL N --- RTI ----------- 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 95 eilksarqladiiempqediakltetdkkd FWMQLN PE ltqdlvskkeidkfrdkditgkeldk K IED L KRKRVTDKNLQ 174
Cdd:PRK10795 87 ------------------------------ YQLEMM PE -------------------------- K VDN L QQTLDALRSVV 110
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 175 E LT AK DI EVLAIKSKMTSG F QMA P qi I K KDVS E QEY A VISE N LAKL PGV DASVDWE R I Y VNDGLFRS V L G N VS NA - D EGL 253
Cdd:PRK10795 111 D LT DD DI AAFRKERARSRR F TSI P -- V K TNLT E VQV A RFAV N QYRF PGV EVKGYQR R Y Y PYGSALTH V I G Y VS KI n D KDV 188
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 254 pr ERLD YY - LVRD Y SRNDRV GK SY IE QQ YEDVLHG TK -- K EV R si ADKQ G NTM R TETVSEGKS G KNLT LT I D ME LQ K kve 330
Cdd:PRK10795 189 -- ERLD KE g KLAN Y AATHDI GK LG IE RY YEDVLHG KT gy E EV E -- VNNR G RVI R QLHEQPPQA G HDIY LT L D LK LQ Q --- 261
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 331 e S IE KI L K qyk GS esmld RA F VV MMN P KN G QV L SMAGKK ---------- LVE KD -- G KMEVEDYA L GTLTSS -- Y ELG ST 396
Cdd:PRK10795 262 - Y IE TL L A --- GS ----- RA A VV VTD P RT G GI L ALVSTP sydpnlfvdg ISS KD ys G LLNDPNRP L INRATQ gv Y PPA ST 332
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 397 VK GATVLTGFETNA IT PG T HFY D A ----- P MKF K GTKEK K S W KN f G DIDDLRA L QV S SNVYMFNI A LKIA gvdyvknssl 471
Cdd:PRK10795 333 VK PYVAVSALSAGV IT RN T SLF D P gwwql P GSE K RYRDW K K W GH - G RLNVTKS L EE S ADTFFYQV A YDMG ---------- 401
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 472 dikqey F D KMRYYFRQ FG L G VQ TGIDL PN E TA G QIGRKDNQ --------- P G FLLDYS IGQ - Y D T Y TP L Q LAQYIS T IA N 541
Cdd:PRK10795 402 ------ I D RLSEWMGK FG Y G HY TGIDL AE E RS G NMPTREWK qkrfkkpwy Q G DTIPVG IGQ g Y W T A TP I Q MSKALM T LI N 475
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 542 G G YRMK P QIVQEIR E Q tvqkdev GK V V QSIE P VVLNRI D MKQE Y INQV K E G FRK V FQEGD GT GVRA F QK APYK P A G K T GT 621
Cdd:PRK10795 476 D G IVKV P HLLMSTA E D ------- GK Q V PWVQ P HEPPVG D IHSG Y WEIA K D G MYG V ANRPN GT AHKY F AS APYK I A A K S GT 548
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446666441 622 AQ t V Y G gend IGR NE K ------ GD R RECYN L TL A g Y APY DD P E VA FSVV vpw V EN DKS G IN - SD I GKEV LD 685
Cdd:PRK10795 549 AQ - V F G ---- LKA NE T ynahki AE R LRDHK L MT A - F APY NN P Q VA VAII --- L EN GGA G PA v GT I MRQI LD 610
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
1-693
7.71e-149
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 445.04
E-value: 7.71e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 1 MK K qe KK SG R VVPL RL NI LFL C V F LLF SGI V IQ L GKV Q IFD G ET Y KNEV E KRENT TV GLSV PRG K I F DR E GN PVVD N KSL 80
Cdd:COG0768 1 MK R -- KK EK R LFRR RL LL LFL L V L LLF LLL V GR L FYL Q VVE G DE Y AELA E ENRIR TV PIPA PRG L I Y DR N GN VLAT N VPV 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 81 RTITYTKVKGVKQ EE I lks A RQ LA DIIEMPQ E DIA K L tetdkkdfwmqlnpeltqdlvskkeidkfrdkditgkeldkki 160
Cdd:COG0768 79 YSLYADPEEVKDP EE T --- A EK LA KLLGLDP E ELR K K ------------------------------------------- 112
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 161 ed LK R K R vtdknlqeltakdievlaikskmts G F qma P QII K KDV S EQ E Y A V I se NLA KLPGV DASVDWE R I Y VNDG L FR 240
Cdd:COG0768 113 -- LK K K S ------------------------- R F --- P VYL K RNL S PE E A A R I -- RAL KLPGV YVEAEYK R Y Y PYGE L AA 160
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 241 S VLG N V SNA deglprerldyylvrdy SRN D RV GKS YI E QQ YED V L H GT KKEV R SIA D KQ G NTM R T - ETVSEGKS GK N L T L 319
Cdd:COG0768 161 H VLG Y V GEI ----------------- NGG D GI GKS GL E KA YED L L R GT PGKR R VEV D AR G RVI R D l GEEKPPVP GK D L V L 223
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 320 TID ME LQK KV EE SIE K ILKQ YK G sesml DRAF VV M M N PK N G QV L S MA GK ------ KL V EKDG kmev E DYALGTLTSS YE L 393
Cdd:COG0768 224 TID SD LQK IA EE ALK K AVEE YK A ----- KSGA VV V M D PK T G EI L A MA SY psfdpn LF V GGPD ---- E PLRNRAVQGT YE P 294
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 394 GST V K GA T VLTGF E TNA ITP G T H F YD - APMKFK G TK e KKS W K -- NF G DIDDLR AL QV SSNV YMFNI AL KI a G V D yvknss 470
Cdd:COG0768 295 GST F K PF T AAAAL E EGV ITP D T T F DC p GYYRVG G RT - IRD W D rg GH G TLTLTE AL AK SSNV GFYKL AL RL - G I D ------ 366
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 471 ldikqeyfd K MRY Y FRQ FGLG VQ TGIDLP N E TA G QIGRKDN - Q PG FLLDY SIGQ YDTY TPLQLAQ YIST IANGG YRM KP Q 549
Cdd:COG0768 367 --------- K LYD Y LKK FGLG QK TGIDLP G E AS G LLPSPKR w Y PG ETATM SIGQ GLSV TPLQLAQ AYAA IANGG VLV KP H 437
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 550 I V Q EI R eqtvqk D EV G K VV QS i EP V VL N R I d MKQ E YINQ V K EG FRK V FQ E GD GT GV RA f QKAP Y KP AGKTGTAQ T V ygge 629
Cdd:COG0768 438 L V K EI V ------ D PD G E VV KE - EP E VL R R V - ISP E TAET V R EG MEG V VN E PG GT AR RA - AIPG Y RV AGKTGTAQ V V ---- 504
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446666441 630 n DIG RNEKGDR R ec YNLTLA G Y AP Y D D P EV A FS VVV PWVENDKS G -- INSDIGK E VLD AY FD L KNK 693
Cdd:COG0768 505 - DIG NGGYYKG R -- HIASFV G F AP A D N P RY A VA VVV ENPGGGAY G gt VAAPVFR E IME AY LR L LGP 567
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
15-689
2.46e-114
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 356.45
E-value: 2.46e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 15 R LNI L FLC V FL LF SGIVIQ L GKV Q IFD GE T Y KNEV E KRENTT V GLSV PRG K I F DR E G NPVV DN KSLRTITYTKV K GVKQE 94
Cdd:TIGR03423 2 R ALV L GGL V LA LF GVLAAR L FYL Q VIR GE E Y ATLS E DNRIRL V PIPP PRG L I L DR N G VLLA DN RPSFSLEIVPE K VDDLD 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 95 EI L ksa RQ LA DIIEMPQ EDIA K ltetdkkdfwmqlnpeltqdlvskkeidkfrdkditgkeldk KIED LKR K R vtdknlq 174
Cdd:TIGR03423 82 AT L --- DR LA KLLDLDP EDIA R ------------------------------------------ FLKE LKR S R ------- 109
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 175 eltakdievlaikskmts G F Q ma P QII K K D VS E Q E Y A VISE N LAK LPGV DASVDWE R I Y VNDG L FRS VLG N V S -- N ADE g 252
Cdd:TIGR03423 110 ------------------ R F E -- P IPL K S D LT E E E V A RFAV N QYR LPGV EIEARLK R Y Y PYGE L AAH VLG Y V G ei N EED - 168
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 253 lp R ERL DY ylv RD Y SRN D RV GKS Y IE QQ YED V L H G TKKEVRSIADKQ G NTM RT ETVSEGKS GK N L T LTID ME LQ KK vees 332
Cdd:TIGR03423 169 -- L ERL EP --- AN Y AGG D YI GKS G IE KY YED E L R G KPGYREVEVNAR G RVI RT LSRVPPVP GK D L V LTID AR LQ QA ---- 239
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 333 I EK I L KQYK G S esmldraf VV M M N P KN G QV L S M AGK ------ KL V E ---- KD G K M -- EVE D YA L -- GTLTSS Y EL GST V K 398
Cdd:TIGR03423 240 A EK A L GGRR G A -------- VV V M D P RT G EI L A M VST psfdpn LF V D giss KD Y K A ll NDP D RP L ln RAIQGV Y PP GST F K 311
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 399 GATV L TGF E TNA ITP G T HF Y D a P MK F K - G TKEKKS WK -- NF G DI D DLR A LQV S SN VY MFNI AL KI a G V D yvknssldikq 475
Cdd:TIGR03423 312 PVVA L AAL E EGV ITP E T RI Y C - P GY F Q l G GRRFRC WK rg GH G RV D LRK A IEE S CD VY FYQL AL RL - G I D ----------- 378
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 476 eyfd K MRY Y FRQ FG L G VQ TGIDLP N E TA G QIG ------ RKDN QP --- G FL L DY SIGQ - Y DTY TPLQLA QYISTI ANGG YR 545
Cdd:TIGR03423 379 ---- K IAE Y AKR FG F G QK TGIDLP G E KS G LVP srewkr KRFG QP wyp G DT L NV SIGQ g Y VLV TPLQLA VATAAL ANGG KL 454
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 546 M KP QI V QE I REQT vqkdev G K VV QSI EP V VL NRIDMKQ E YINQ V K EG F R K V FQEGD GT GV RA FQKA PYK P AGKTGTAQ T V 625
Cdd:TIGR03423 455 Y KP HL V KS I EDPD ------ G G VV RRT EP E VL RPLPISP E NLDV V R EG M R D V VNGPG GT AR RA RLGL PYK M AGKTGTAQ V V 528
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446666441 626 YGGENDIGRN E KGDR R ECYNLTLAGY APYD D P EV A FS V V vpw VE NDKS G -- INSD I GKEVL DAY FD 689
Cdd:TIGR03423 529 SLKQGEKYDA E QIPE R LRDHALFVAF APYD N P KI A VA V I --- VE HGGG G ss AAAP I ARKIM DAY LL 591
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
350-685
3.18e-71
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 233.85
E-value: 3.18e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 350 AFV V MMN PK N G Q VL S M A GK K lv EK D GKMEVEDYALGTL TS S YE L GST V K GA T V L TGFETNAIT P GTHFY D A P M K FK G T K E 429
Cdd:pfam00905 1 GSA V VLD PK T G E VL A M V GK P -- SY D PNGFIGPLRNRAV TS R YE P GST F K PF T A L AALDNGVLK P DETIF D W P G K QQ G G K S 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 430 KKS W KNFGD - I DD LR - AL QV SSN V YM FNI A L K IA gvdyvknssldikqey F DK M R Y Y FRQ FG L G VQ TGI D LP N E T AG QIG 507
Cdd:pfam00905 79 IGD W NQDQV g I GT LR q AL EY SSN W YM QKL A Q K LG ---------------- A DK L R S Y LKK FG Y G NK TGI G LP G E N AG YLT 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 508 RKDNQ p G FLLDYS IG qy D T Y TPLQ L AQ YIST IANGG YRMK P QI V QE I reqtvqkdevgkv VQSIE P V VLN RIDMKQEYIN 587
Cdd:pfam00905 143 PYWLE - G ATASFG IG -- L T I TPLQ Q AQ AYAA IANGG KLVP P HL V KS I ------------- EDKVD P K VLN KLPISKSTAE 206
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 588 Q VK EGF R K V fq EG DGTG VRAFQKAP YK P AGKTGTAQ TVYGGEN digrnek G DRRECYNLTLA GYAP Y D D P EV AF S V VVPW 667
Cdd:pfam00905 207 K VK DML R L V -- VN DGTG TGTAAVPG YK V AGKTGTAQ VAGPKGG ------- G YYDGAQIGWFV GYAP A D N P KY AF A V LIDD 277
330
....*....|....*....
gi 446666441 668 VENDKS G INSD - I G K EV L D 685
Cdd:pfam00905 278 PKRYYG G KVAA p I F K DI L E 296
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
15-685
2.15e-39
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 154.54
E-value: 2.15e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 15 R LNIL FL CVF LL FSGIVIQ L GKV QI FDGET Y KNEVEKRENTT V GLSVP RG K I F DR E G N P VVD N ksl RTI tytkvkgvkqe 94
Cdd:PRK10795 21 R ALVA FL GIL LL TGVLIAN L YNL QI VRFTD Y QTRSNENRIKL V PIAPS RG I I Y DR N G T P LAL N --- RTI ----------- 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 95 eilksarqladiiempqediakltetdkkd FWMQLN PE ltqdlvskkeidkfrdkditgkeldk K IED L KRKRVTDKNLQ 174
Cdd:PRK10795 87 ------------------------------ YQLEMM PE -------------------------- K VDN L QQTLDALRSVV 110
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 175 E LT AK DI EVLAIKSKMTSG F QMA P qi I K KDVS E QEY A VISE N LAKL PGV DASVDWE R I Y VNDGLFRS V L G N VS NA - D EGL 253
Cdd:PRK10795 111 D LT DD DI AAFRKERARSRR F TSI P -- V K TNLT E VQV A RFAV N QYRF PGV EVKGYQR R Y Y PYGSALTH V I G Y VS KI n D KDV 188
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 254 pr ERLD YY - LVRD Y SRNDRV GK SY IE QQ YEDVLHG TK -- K EV R si ADKQ G NTM R TETVSEGKS G KNLT LT I D ME LQ K kve 330
Cdd:PRK10795 189 -- ERLD KE g KLAN Y AATHDI GK LG IE RY YEDVLHG KT gy E EV E -- VNNR G RVI R QLHEQPPQA G HDIY LT L D LK LQ Q --- 261
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 331 e S IE KI L K qyk GS esmld RA F VV MMN P KN G QV L SMAGKK ---------- LVE KD -- G KMEVEDYA L GTLTSS -- Y ELG ST 396
Cdd:PRK10795 262 - Y IE TL L A --- GS ----- RA A VV VTD P RT G GI L ALVSTP sydpnlfvdg ISS KD ys G LLNDPNRP L INRATQ gv Y PPA ST 332
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 397 VK GATVLTGFETNA IT PG T HFY D A ----- P MKF K GTKEK K S W KN f G DIDDLRA L QV S SNVYMFNI A LKIA gvdyvknssl 471
Cdd:PRK10795 333 VK PYVAVSALSAGV IT RN T SLF D P gwwql P GSE K RYRDW K K W GH - G RLNVTKS L EE S ADTFFYQV A YDMG ---------- 401
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 472 dikqey F D KMRYYFRQ FG L G VQ TGIDL PN E TA G QIGRKDNQ --------- P G FLLDYS IGQ - Y D T Y TP L Q LAQYIS T IA N 541
Cdd:PRK10795 402 ------ I D RLSEWMGK FG Y G HY TGIDL AE E RS G NMPTREWK qkrfkkpwy Q G DTIPVG IGQ g Y W T A TP I Q MSKALM T LI N 475
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 542 G G YRMK P QIVQEIR E Q tvqkdev GK V V QSIE P VVLNRI D MKQE Y INQV K E G FRK V FQEGD GT GVRA F QK APYK P A G K T GT 621
Cdd:PRK10795 476 D G IVKV P HLLMSTA E D ------- GK Q V PWVQ P HEPPVG D IHSG Y WEIA K D G MYG V ANRPN GT AHKY F AS APYK I A A K S GT 548
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446666441 622 AQ t V Y G gend IGR NE K ------ GD R RECYN L TL A g Y APY DD P E VA FSVV vpw V EN DKS G IN - SD I GKEV LD 685
Cdd:PRK10795 549 AQ - V F G ---- LKA NE T ynahki AE R LRDHK L MT A - F APY NN P Q VA VAII --- L EN GGA G PA v GT I MRQI LD 610
PBP_dimer
pfam03717 Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of ...
59-301
7.03e-32
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerization. The domain forms a largely disordered 'sugar tongs' structure.
Pssm-ID: 427460 [Multi-domain]
Cd Length: 178
Bit Score: 122.05
E-value: 7.03e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 59 LSV PRG K I F DR E G NPVVD NK SLRTI T Y T K v KGV K QEEI LK S A RQ LA DII empqediakltetdkkdfwmqlnpeltqdlv 138
Cdd:pfam03717 2 IPA PRG E I Y DR N G VVLAT NK PVYSL T I T P - SKL K KADA LK T A LK LA KLL ------------------------------- 49
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 139 skkeidkfrdkditgkeld KKI EDL KRKRV T DKN L qeltakdievlaiks KM T S GFQMA P QI IKK DV SE Q E Y A V I S ENL A 218
Cdd:pfam03717 50 ------------------- SNY EDL DDEDL T ERF L --------------- KM N S YKSYY P VV IKK NL SE E E V A R I E ENL L 95
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 219 K LPGV DASV D WE R I Y VNDG L FRSV LG N V SNAD E glpr E R L DY YL VRD YSR N D R VGKS YI E Q QYE D VL H G TKKEVRSIA D K 298
Cdd:pfam03717 96 E LPGV SIET D PV R Y Y PYGE L AAHL LG Y V GEIT E ---- E E L EK YL DKG YSR G D L VGKS GL E K QYE S VL R G KDGVRQVEV D A 171
...
gi 446666441 299 Q G N 301
Cdd:pfam03717 172 L G R 174
MrcB
COG0744 Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
320-623
1.10e-27
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain]
Cd Length: 630
Bit Score: 118.87
E-value: 1.10e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 320 T I D ME LQK KV E ESIEKI L KQY K GSES mld R A FV V MMN PK N G Q VL S M A G KK lvek D GKMEVEDY A LGTL tss YEL GST V K G 399
Cdd:COG0744 300 T L D PK LQK AA E KAVKNV L PEG K PGGL --- Q A AL V VVD PK T G E VL A M V G GR ---- D YGKSQFNR A TQAK --- RQP GST F K P 369
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 400 ATVLTGF E TN a I TP G T HFY D A P MK F K G tkek KS W -- KN F ----- G DIDDLR AL QV S S N VYMFNI A LKI a G V D Y V K nssld 472
Cdd:COG0744 370 FVYAAAL E QG - Y TP A T TVD D E P VT F P G ---- GG W sp KN Y dgryr G PVTLRE AL AN S L N TPAVRL A QEV - G L D K V V ----- 438
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 473 ikq EYFDKM ryyfrqfglgvqt GI DL P netagqigr K D NQ P GFL L dysi G QYDT y T PL QL A QYIS T I ANGG YRMK P QIVQ 552
Cdd:COG0744 439 --- DTARRL ------------- GI TS P --------- L D PN P SLA L ---- G TSEV - S PL EM A SAYA T F ANGG VYVE P HAIT 488
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446666441 553 EIR eqtvqk D EV GKV VQSIE P VVLNR I D mk Q E YINQVKEGFRK V FQE G D G TGV R a FQKA P Y kp AGKTGT AQ 623
Cdd:COG0744 489 KVT ------ D AD GKV LYEAK P KCEQV I S -- P E VAYLMTDMLQD V VTS G T G RAA R - LPGR P V -- AGKTGT TN 548
PBP_1a_fam
TIGR02074 penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ...
319-674
1.15e-12
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain]
Cd Length: 531
Bit Score: 70.75
E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 319 L T I D MEL QK KV E ESIEKI L KQYKGSESMLDR A FV V MMN P KN G Q V LSMA G KKLVE K DGK meve DY A LGTLTSS yel GST V K 398
Cdd:TIGR02074 226 T T L D LDA QK AA E KVLNTG L RVAGRRDGDDLQ A AL V AID P DT G A V RALV G GRDYG K SQF ---- NR A TQAKRQP --- GST F K 298
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 399 GATVLTGF E T n AI TP G T HFY D A P MKFK G TK ekk S W -- KN F ----- G DIDDLR AL QV S S N VYMFNIALKI a G V D Y V K nssl 471
Cdd:TIGR02074 299 PFVYAAAL E K - GL TP A T IVN D E P ITYN G NG --- P W sp KN Y gggyr G NVTLRQ AL AQ S R N IPAVRLLQEV - G L D K V V ---- 369
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 472 dikqeyfdkmr YYFRQ FG L gvqtgidlpnetagqigrk DNQPGFL L DYSI G QYDT y T PL QL A QYISTI ANGG YRMK P QIV 551
Cdd:TIGR02074 370 ----------- ALAKR FG I ------------------- TSPLDPV L SLAL G TVEV - S PL EM A SAYAVF ANGG KYVE P HGI 418
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 552 QE I R eqtvqk D EV GKV VQSIE P VVLNR I DMKQE YI - NQV keg FRK V FQE G D G TGV R AFQ kap YKP AGKTGT A Q tvyggen 630
Cdd:TIGR02074 419 RK I V ------ D RD GKV IYENK P KTTQV I SPATA YI m TDM --- LKG V VES G T G RSA R LPG --- RPV AGKTGT T Q ------- 479
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 446666441 631 digr N EK gdrrecy NLTLA GY A PY ddpeva FSVV V p WV EN D KSG 674
Cdd:TIGR02074 480 ---- N WR ------- DAWFV GY T PY ------ YVTA V - WV GY D DKK 505
MrcA
COG5009 Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
350-621
5.16e-11
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain]
Cd Length: 785
Bit Score: 65.95
E-value: 5.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 350 A F V VM m N P KN G Q VL SMA G kklvekdgkmevedyal G tlt SSY E L ------------- GS TV K ---- G A TVLT G F etnai T 412
Cdd:COG5009 424 A L V AL - D P HT G A VL ALV G ----------------- G --- FDF E Q skfnratqakrqp GS SF K pfvy A A ALDN G Y ----- T 477
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 413 P G T HFY DAP MK F KGTKEKKS W -- KN FGDIDD ---- LR - AL QV S S N VYMFNIALKI a G V DYV KN ssldikqeyfdkmry Y F 485
Cdd:COG5009 478 P A T IIN DAP IV F DDGGGGGV W rp KN YSGKFY gptt LR e AL EK S R N LVTVRLLQDV - G I DYV ID --------------- Y A 541
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 486 RQ FG LGVQ tgid LP N etagqigrkdnqpgfll DY S I -- G QYDT y TPL QL A QYISTI ANGGYR MK P QIVQE I reqtvq K D E 563
Cdd:COG5009 542 ER FG IYSK ---- LP P ----------------- NL S L al G SGEV - TPL EM A RAYAVF ANGGYR VE P YLIDR I ------ E D R 593
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446666441 564 V GKV VQSIE P VVLNRIDMKQ E YINQVKEGF ------------------- R K V F Q E G D G TGV RA FQ kapy KP - AGKTGT 621
Cdd:COG5009 594 N GKV IYRAD P ARACEDCDAA E WDGAEPRLP dpaeqvidprtayqmtsml R G V V Q R G T G RRA RA LG ---- RD i AGKTGT 667
PRK15105
PRK15105 peptidoglycan synthase FtsI; Provisional
277-665
1.01e-10
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain]
Cd Length: 578
Bit Score: 64.84
E-value: 1.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 277 I E QQYEDV L H G TKK E VRSIA D KQ G NTMRTETVSEGKSGK NL T L T ID ME LQ KK V EESIEKILKQY K g S ES mldr AFV V MMN 356
Cdd:PRK15105 191 V E KSFDKW L T G QPG E RIVRK D RY G RVIEDISSTDSQAAH NL A L S ID ER LQ AL V YRELNNAVAFN K - A ES ---- GSA V LVD 265
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 357 PKN G Q VL S MA GKKLVEKDGKMEVEDY A LG -- TL T SSY E L GSTVK GAT V L T GFETNAITPGTHFYDA P MKFK G t K E K K SWK 434
Cdd:PRK15105 266 VNT G E VL A MA NSPSYNPNNLSGTPKD A MR nr AI T DVF E P GSTVK PMV V M T ALQRGVVKENSVLNTV P YRIN G - H E I K DVA 344
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 435 NFGDIDDLRA LQ V SSNV YMFNI AL KIAGVDY V KNS S ldikqeyfdkmryyfr Q FGLG VQ T GID L PN E TA G QIGR K DNQPG 514
Cdd:PRK15105 345 RYSELTLTGV LQ K SSNV GVSKL AL AMPSSAL V DTY S ---------------- R FGLG KA T NLG L VG E RS G LYPQ K QRWSD 408
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446666441 515 F - LLDY S I G QYDTY TPLQLA QYIS TI ANG G - YR mk P QIVQEIR ----- E QTVQKDE V GK VV QSI E P V V L N ridmkqeyin 587
Cdd:PRK15105 409 I e RATF S F G YGLMV TPLQLA RVYA TI GSY G i YR -- P LSITKVD ppvpg E RVFPESI V RT VV HMM E S V A L P ---------- 476
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446666441 588 qvkegfrkvfqeg D G T GV R A FQ K A p Y KP A G KTGTA QT V YGGEND I GR nekgdrrec Y NLTL AG Y AP YDD P EV A FS VV V 665
Cdd:PRK15105 477 ------------- G G G GV K A AI K G - Y RI A I KTGTA KK V GPDGRY I NK --------- Y IAYT AG V AP ASQ P RF A LV VV I 531
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
