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Conserved domains on  [gi|446678469|ref|WP_000755815|]
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MULTISPECIES: glucan-binding protein [Bacillus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pneumo_PspA super family cl41532
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 41-305 1.89e-59

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


The actual alignment was detected with superfamily member NF033930:

Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 202.45  E-value: 1.89e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  41 KRGWFQGTGYWLYYNEDGSLAIGWKNINGKWYhfdetgmmatymkniqgktyYFNEDGSMQIGWKKVR-VWHYFNEDGSM 119
Cdd:NF033930 442 KTGWKQENGMWYFYNTDGSMATGWLQNNGSWY--------------------YLNSNGAMATGWLQYNgSWYYLNANGAM 501

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 120 AKDWKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEiksgpYTGKWFYYNADGAMATGWAQVKGKWYYFD 199
Cdd:NF033930 502 ATGWAKVNGSWYYL--------------------NANGAMATGWLQ-----YNGSWYYLNANGAMATGWLKYNGSWYYLN 556

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 200 ASGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYvfddtgamrkgklaeggtvwYFNEDGSMLTGWKQLE 279
Cdd:NF033930 557 ANGAMATGWLQYNGSWYYLNANGAMAT-------GWAKVNGSWY--------------------YLNANGSMATGWVKDG 609

                        250       260
                 ....*....|....*....|....*..
gi 446678469 280 EGWYYFnDQSGASEQG-WFSNKGKWYY 305
Cdd:NF033930 610 DTWYYL-EASGAMKASqWFKVSDKWYY 635
PspC_relate_1 super family cl41464
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 273-351 8.92e-20

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


The actual alignment was detected with superfamily member NF033840:

Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 90.53  E-value: 8.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 273 TGWKQlEEGWYYFNDQSGASEQGWFSNKGKWYYF-EDGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:NF033840 510 TGWKQ-ENGMWYFYNTDGSMATGWVQVNGSWYYLnSNGSMATGWVQVNGSWYYLNSNGSMATGWVQVDGSWYYLNDNGSM 588
 
Name Accession Description Interval E-value
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 41-305 1.89e-59

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 202.45  E-value: 1.89e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  41 KRGWFQGTGYWLYYNEDGSLAIGWKNINGKWYhfdetgmmatymkniqgktyYFNEDGSMQIGWKKVR-VWHYFNEDGSM 119
Cdd:NF033930 442 KTGWKQENGMWYFYNTDGSMATGWLQNNGSWY--------------------YLNSNGAMATGWLQYNgSWYYLNANGAM 501

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 120 AKDWKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEiksgpYTGKWFYYNADGAMATGWAQVKGKWYYFD 199
Cdd:NF033930 502 ATGWAKVNGSWYYL--------------------NANGAMATGWLQ-----YNGSWYYLNANGAMATGWLKYNGSWYYLN 556

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 200 ASGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYvfddtgamrkgklaeggtvwYFNEDGSMLTGWKQLE 279
Cdd:NF033930 557 ANGAMATGWLQYNGSWYYLNANGAMAT-------GWAKVNGSWY--------------------YLNANGSMATGWVKDG 609

                        250       260
                 ....*....|....*....|....*..
gi 446678469 280 EGWYYFnDQSGASEQG-WFSNKGKWYY 305
Cdd:NF033930 610 DTWYYL-EASGAMKASqWFKVSDKWYY 635
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 123-343 1.68e-56

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 194.75  E-value: 1.68e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 123 WKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEiksgpYTGKWFYYNADGAMATGWAQVKGKWYYFDASG 202
Cdd:NF033930 445 WKQENGMWYFY--------------------NTDGSMATGWLQ-----NNGSWYYLNSNGAMATGWLQYNGSWYYLNANG 499

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 203 VMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYVFDDTGAMRKGKLAEGGTVWYFNEDGSMLTGWKQLEEGW 282
Cdd:NF033930 500 AMATGWAKVNGSWYYLNANGAMAT-------GWLQYNGSWYYLNANGAMATGWLKYNGSWYYLNANGAMATGWLQYNGSW 572

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446678469 283 YYFNdQSGASEQGWFSNKGKWYYFE-DGPMKTGWLQENKNWYYLQSSGDMAVGKHL-INGKWY 343
Cdd:NF033930 573 YYLN-ANGAMATGWAKVNGSWYYLNaNGSMATGWVKDGDTWYYLEASGAMKASQWFkVSDKWY 634
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 123-342 1.07e-53

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 187.53  E-value: 1.07e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 123 WKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEiksgpYTGKWFYYNADGAMATGWAQVKGKWYYFDASG 202
Cdd:NF033838 488 WKQENGMWYFY--------------------NTDGSMATGWLQ-----NNGSWYYLNANGAMATGWLQNNGSWYYLNANG 542

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 203 VMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYVFDDTGAMRKGKLAEGGTVWYFNEDGSMLTGWKQLEEGW 282
Cdd:NF033838 543 SMATGWLQNNGSWYYLNANGAMAT-------GWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDMATGWLQYNGSW 615

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446678469 283 YYFNdQSGASEQGWFSNKGKWYYFE-DGPMKTG-WLQENKNWYYLQSSGDMAVGKHL------INGKW 342
Cdd:NF033838 616 YYLN-ANGSMATGWVKDGDTWYYLEaSGAMKASqWFKVSDKWYYVNGSGALAVNTTVdgygvnANGEW 682
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 20-251 1.16e-52

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 184.83  E-value: 1.16e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  20 SHAEENVVSQKKADTIEQVQE----KRGWFQGTGYWLYYNEDGSLAIGWKNINGKWYHFDETGMMATYMKNIQGKTYYFN 95
Cdd:NF033838 460 SEEEYNRLTQQQPPKTEKPAQpstpKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLN 539

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  96 EDGSMQIGWKKVR-VWHYFNEDGSMAKDWKKINGSWYHfdkdgymsdgrrtiggktytFNADGTMVTGWQEiksgpYTGK 174
Cdd:NF033838 540 ANGSMATGWLQNNgSWYYLNANGAMATGWLQYNGSWYY--------------------LNANGDMATGWLQ-----YNGS 594

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446678469 175 WFYYNADGAMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKSTEnnwnegWLEENGKRYVFDDTGAM 251
Cdd:NF033838 595 WYYLNANGDMATGWLQYNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQ------WFKVSDKWYYVNGSGAL 665
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 101-305 3.39e-52

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 183.29  E-value: 3.39e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 101 QIGWKKVR-VWHYFNEDGSMAKDWKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEiksgpYTGKWFYYN 179
Cdd:NF033838 485 KTGWKQENgMWYFYNTDGSMATGWLQNNGSWYYL--------------------NANGAMATGWLQ-----NNGSWYYLN 539

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 180 ADGAMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYVFDDTGAMRKGKLAEG 259
Cdd:NF033838 540 ANGSMATGWLQNNGSWYYLNANGAMATGWLQYNGSWYYLNANGDMAT-------GWLQYNGSWYYLNANGDMATGWLQYN 612

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446678469 260 GTVWYFNEDGSMLTGWKQLEEGWYYFNDQSGASEQGWFSNKGKWYY 305
Cdd:NF033838 613 GSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYY 658
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 149-351 6.72e-46

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 165.96  E-value: 6.72e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 149 KTYTFNADGTMVTGW-QEiksgpyTGKWFYYNADGAMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKSt 227
Cdd:NF033838 474 KTEKPAQPSTPKTGWkQE------NGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLNANGSMAT- 546

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 228 ennwneGWLEENGKRYvfddtgamrkgklaeggtvwYFNEDGSMLTGWKQLEEGWYYFNdqsgaseqgwfsnkgkwyyfE 307
Cdd:NF033838 547 ------GWLQNNGSWY--------------------YLNANGAMATGWLQYNGSWYYLN--------------------A 580

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 446678469 308 DGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:NF033838 581 NGDMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGSM 624
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
41-226 1.98e-43

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 156.57  E-value: 1.98e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  41 KRGWFQGTGYWLYYNEDGSLAIGWKNINGKWYHFDETGMMATYMKNIQGKTYYFNEDGSMQIGWKKVR-VWHYFNEDGSM 119
Cdd:COG5263  305 VTGWQTINGKWYYFDSDGAMATGWQKINGKWYYFDEDGAMATGWVTDDGKWYYLGSDGAMATGWQKIDgKWYYFDSNGAM 384

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 120 AKDWKKINGSWYHFDKDGYMSDGRRTIGGKTYTFNADGTMVTGWQEIKsgpytGKWFYYNADGAMATGWAQVKGKWYYFD 199
Cdd:COG5263  385 ATGWVKVDGKWYYFDSSGAMATGWLKIDGKWYYFDSDGAMATGWQKIG-----GKWYYFDSNGAMATGWVKVDGKWYYFD 459

                        170       180
                 ....*....|....*....|....*..
gi 446678469 200 ASGVMQTGWLKNNNVWYYLNTDGSMKS 226
Cdd:COG5263  460 SDGAMATGWQTIDGKTYYFDSNGAWVG 486
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 103-251 2.28e-37

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 141.76  E-value: 2.28e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 103 GWKKVR-VWHYFNEDGSMAKDWKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEIksgpyTGKWFYYNAD 181
Cdd:NF033840 511 GWKQENgMWYFYNTDGSMATGWVQVNGSWYYL--------------------NSNGSMATGWVQV-----NGSWYYLNSN 565

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 182 GAMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKSTEnnwnegWLEENGKRYVFDDTGAM 251
Cdd:NF033840 566 GSMATGWVQVDGSWYYLNDNGSMETGWLQNNGSWYYLNSNGSMKANQ------WFQVGSKWYYVNASGEL 629
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 183-342 2.45e-36

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 139.06  E-value: 2.45e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 183 AMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYvfddtgamrkgklaeggtv 262
Cdd:NF033840 507 APTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMAT-------GWVQVNGSWY------------------- 560

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 263 wYFNEDGSMLTGWKQLEEGWYYFNDqSGASEQGWFSNKGKWYYF-EDGPMKTG-WLQENKNWYYLQSSGDMAVGKHL--- 337
Cdd:NF033840 561 -YLNSNGSMATGWVQVDGSWYYLND-NGSMETGWLQNNGSWYYLnSNGSMKANqWFQVGSKWYYVNASGELAVNTSIdgy 638


                 ....*...
gi 446678469 338 ---INGKW 342
Cdd:NF033840 639 rvnDNGEW 646
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 234-351 3.11e-23

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 100.93  E-value: 3.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 234 GWLEENGkryvfddtgamrkgklaeggtVWYF-NEDGSMLTGWKQLEEGWYYFNdQSGASEQGWFSNKGKWYYF-EDGPM 311
Cdd:NF033840 511 GWKQENG---------------------MWYFyNTDGSMATGWVQVNGSWYYLN-SNGSMATGWVQVNGSWYYLnSNGSM 568

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 446678469 312 KTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:NF033840 569 ATGWVQVDGSWYYLNDNGSMETGWLQNNGSWYYLNSNGSM 608
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 273-351 8.92e-20

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 90.53  E-value: 8.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 273 TGWKQlEEGWYYFNDQSGASEQGWFSNKGKWYYF-EDGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:NF033840 510 TGWKQ-ENGMWYFYNTDGSMATGWVQVNGSWYYLnSNGSMATGWVQVNGSWYYLNSNGSMATGWVQVDGSWYYLNDNGSM 588
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 291-351 3.77e-14

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 73.58  E-value: 3.77e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446678469 291 ASEQGWFSNKGKWYYFE-DGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:NF033840 507 APTTGWKQENGMWYFYNtDGSMATGWVQVNGSWYYLNSNGSMATGWVQVNGSWYYLNSNGSM 568
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 160-204 8.84e-08

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 47.92  E-value: 8.84e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 446678469  160 VTGWQEIKsgpytGKWFYYNADGAMATGW-AQVKGKWYYFDA-SGVM 204
Cdd:pfam19127   1 VTGWQTIN-----GQTLYFDSDGKQVKGWvVTIDGKWYYFDAdSGEM 42
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 111-169 1.01e-05

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 42.51  E-value: 1.01e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446678469  111 HYFNEDGSMAKDWKKINGSWYHFDKDGYMSDGR-RTIGGKTYTFNAD-GTMVT-GWQEIKSG 169
Cdd:TIGR04035   1 YYFDADGKAVTGAQTIDGVTYYFDENGKQVKGDfVTNGGGTYYYDKDsGALVTnRFVTIKDG 62
 
Name Accession Description Interval E-value
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 41-305 1.89e-59

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 202.45  E-value: 1.89e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  41 KRGWFQGTGYWLYYNEDGSLAIGWKNINGKWYhfdetgmmatymkniqgktyYFNEDGSMQIGWKKVR-VWHYFNEDGSM 119
Cdd:NF033930 442 KTGWKQENGMWYFYNTDGSMATGWLQNNGSWY--------------------YLNSNGAMATGWLQYNgSWYYLNANGAM 501

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 120 AKDWKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEiksgpYTGKWFYYNADGAMATGWAQVKGKWYYFD 199
Cdd:NF033930 502 ATGWAKVNGSWYYL--------------------NANGAMATGWLQ-----YNGSWYYLNANGAMATGWLKYNGSWYYLN 556

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 200 ASGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYvfddtgamrkgklaeggtvwYFNEDGSMLTGWKQLE 279
Cdd:NF033930 557 ANGAMATGWLQYNGSWYYLNANGAMAT-------GWAKVNGSWY--------------------YLNANGSMATGWVKDG 609

                        250       260
                 ....*....|....*....|....*..
gi 446678469 280 EGWYYFnDQSGASEQG-WFSNKGKWYY 305
Cdd:NF033930 610 DTWYYL-EASGAMKASqWFKVSDKWYY 635
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 123-343 1.68e-56

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 194.75  E-value: 1.68e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 123 WKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEiksgpYTGKWFYYNADGAMATGWAQVKGKWYYFDASG 202
Cdd:NF033930 445 WKQENGMWYFY--------------------NTDGSMATGWLQ-----NNGSWYYLNSNGAMATGWLQYNGSWYYLNANG 499

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 203 VMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYVFDDTGAMRKGKLAEGGTVWYFNEDGSMLTGWKQLEEGW 282
Cdd:NF033930 500 AMATGWAKVNGSWYYLNANGAMAT-------GWLQYNGSWYYLNANGAMATGWLKYNGSWYYLNANGAMATGWLQYNGSW 572

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446678469 283 YYFNdQSGASEQGWFSNKGKWYYFE-DGPMKTGWLQENKNWYYLQSSGDMAVGKHL-INGKWY 343
Cdd:NF033930 573 YYLN-ANGAMATGWAKVNGSWYYLNaNGSMATGWVKDGDTWYYLEASGAMKASQWFkVSDKWY 634
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 123-342 1.07e-53

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 187.53  E-value: 1.07e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 123 WKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEiksgpYTGKWFYYNADGAMATGWAQVKGKWYYFDASG 202
Cdd:NF033838 488 WKQENGMWYFY--------------------NTDGSMATGWLQ-----NNGSWYYLNANGAMATGWLQNNGSWYYLNANG 542

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 203 VMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYVFDDTGAMRKGKLAEGGTVWYFNEDGSMLTGWKQLEEGW 282
Cdd:NF033838 543 SMATGWLQNNGSWYYLNANGAMAT-------GWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGDMATGWLQYNGSW 615

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446678469 283 YYFNdQSGASEQGWFSNKGKWYYFE-DGPMKTG-WLQENKNWYYLQSSGDMAVGKHL------INGKW 342
Cdd:NF033838 616 YYLN-ANGSMATGWVKDGDTWYYLEaSGAMKASqWFKVSDKWYYVNGSGALAVNTTVdgygvnANGEW 682
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 20-251 1.16e-52

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 184.83  E-value: 1.16e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  20 SHAEENVVSQKKADTIEQVQE----KRGWFQGTGYWLYYNEDGSLAIGWKNINGKWYHFDETGMMATYMKNIQGKTYYFN 95
Cdd:NF033838 460 SEEEYNRLTQQQPPKTEKPAQpstpKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLN 539

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  96 EDGSMQIGWKKVR-VWHYFNEDGSMAKDWKKINGSWYHfdkdgymsdgrrtiggktytFNADGTMVTGWQEiksgpYTGK 174
Cdd:NF033838 540 ANGSMATGWLQNNgSWYYLNANGAMATGWLQYNGSWYY--------------------LNANGDMATGWLQ-----YNGS 594

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446678469 175 WFYYNADGAMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKSTEnnwnegWLEENGKRYVFDDTGAM 251
Cdd:NF033838 595 WYYLNANGDMATGWLQYNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQ------WFKVSDKWYYVNGSGAL 665
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 101-305 3.39e-52

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 183.29  E-value: 3.39e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 101 QIGWKKVR-VWHYFNEDGSMAKDWKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEiksgpYTGKWFYYN 179
Cdd:NF033838 485 KTGWKQENgMWYFYNTDGSMATGWLQNNGSWYYL--------------------NANGAMATGWLQ-----NNGSWYYLN 539

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 180 ADGAMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYVFDDTGAMRKGKLAEG 259
Cdd:NF033838 540 ANGSMATGWLQNNGSWYYLNANGAMATGWLQYNGSWYYLNANGDMAT-------GWLQYNGSWYYLNANGDMATGWLQYN 612

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446678469 260 GTVWYFNEDGSMLTGWKQLEEGWYYFNDQSGASEQGWFSNKGKWYY 305
Cdd:NF033838 613 GSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYY 658
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 149-351 6.72e-46

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 165.96  E-value: 6.72e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 149 KTYTFNADGTMVTGW-QEiksgpyTGKWFYYNADGAMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKSt 227
Cdd:NF033838 474 KTEKPAQPSTPKTGWkQE------NGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLNANGSMAT- 546

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 228 ennwneGWLEENGKRYvfddtgamrkgklaeggtvwYFNEDGSMLTGWKQLEEGWYYFNdqsgaseqgwfsnkgkwyyfE 307
Cdd:NF033838 547 ------GWLQNNGSWY--------------------YLNANGAMATGWLQYNGSWYYLN--------------------A 580

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 446678469 308 DGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:NF033838 581 NGDMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGSM 624
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
41-226 1.98e-43

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 156.57  E-value: 1.98e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  41 KRGWFQGTGYWLYYNEDGSLAIGWKNINGKWYHFDETGMMATYMKNIQGKTYYFNEDGSMQIGWKKVR-VWHYFNEDGSM 119
Cdd:COG5263  305 VTGWQTINGKWYYFDSDGAMATGWQKINGKWYYFDEDGAMATGWVTDDGKWYYLGSDGAMATGWQKIDgKWYYFDSNGAM 384

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 120 AKDWKKINGSWYHFDKDGYMSDGRRTIGGKTYTFNADGTMVTGWQEIKsgpytGKWFYYNADGAMATGWAQVKGKWYYFD 199
Cdd:COG5263  385 ATGWVKVDGKWYYFDSSGAMATGWLKIDGKWYYFDSDGAMATGWQKIG-----GKWYYFDSNGAMATGWVKVDGKWYYFD 459

                        170       180
                 ....*....|....*....|....*..
gi 446678469 200 ASGVMQTGWLKNNNVWYYLNTDGSMKS 226
Cdd:COG5263  460 SDGAMATGWQTIDGKTYYFDSNGAWVG 486
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
21-352 4.38e-43

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 155.41  E-value: 4.38e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  21 HAEENVVSQKKADTIEQVQEKRGWFQGTGYWLYYNEDGSLAIGWKNINGKWYHFDETGMMATYMKNIQGKTYYFNEDGSM 100
Cdd:COG5263  202 GDAGAYGALGLAAGSGAGAKKTGSTAGASGTAYGDSGGTAGSGLSSLGGSSNALESGGENNQSLAGNGTSYDDAGAAGVD 281

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 101 QIGWKKVRVW----HYFNEDGSMAKDWKKINGSWYHFDKDGYMSDGRRTIGGKTYTFNADGTMVTGWQEIKsgpytGKWF 176
Cdd:COG5263  282 GTGTTGTVGWvdgkWYYFDAGKMVTGWQTINGKWYYFDSDGAMATGWQKINGKWYYFDEDGAMATGWVTDD-----GKWY 356

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 177 YYNADGAMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYvfddtgamrkgkl 256
Cdd:COG5263  357 YLGSDGAMATGWQKIDGKWYYFDSNGAMATGWVKVDGKWYYFDSSGAMAT-------GWLKIDGKWY------------- 416

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 257 aeggtvwYFNEDGSMLTGWKQLEEGWYYFNDqsgaseqgwfsnkgkwyyfeDGPMKTGWLQENKNWYYLQSSGDMAVGKH 336
Cdd:COG5263  417 -------YFDSDGAMATGWQKIGGKWYYFDS--------------------NGAMATGWVKVDGKWYYFDSDGAMATGWQ 469

                        330
                 ....*....|....*.
gi 446678469 337 LINGKWYTFKHNGIMM 352
Cdd:COG5263  470 TIDGKTYYFDSNGAWV 485
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
36-273 1.70e-42

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 153.87  E-value: 1.70e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  36 EQVQEKRGWFQGTGYWLYYNEDGSLAIGWKN-INGKWYHFDeTGMMATYMKNIQGKTYYFNEDGSMQIGWKKVR-VWHYF 113
Cdd:COG5263  260 ENNQSLAGNGTSYDDAGAAGVDGTGTTGTVGwVDGKWYYFD-AGKMVTGWQTINGKWYYFDSDGAMATGWQKINgKWYYF 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 114 NEDGSMAKDWKKINGSWYHFDKDGYMSDGRRTIGGKTYTFNADGTMVTGWQEIKsgpytGKWFYYNADGAMATGWAQVKG 193
Cdd:COG5263  339 DEDGAMATGWVTDDGKWYYLGSDGAMATGWQKIDGKWYYFDSNGAMATGWVKVD-----GKWYYFDSSGAMATGWLKIDG 413

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 194 KWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYVFDDTGAMRKGKLAEGGTVWYFNEDGSMLT 273
Cdd:COG5263  414 KWYYFDSDGAMATGWQKIGGKWYYFDSNGAMAT-------GWVKVDGKWYYFDSDGAMATGWQTIDGKTYYFDSNGAWVG 486
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
46-351 5.89e-39

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 144.24  E-value: 5.89e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  46 QGTGYWLYYNEDGSLAIGWKNINGKWYHFDETGMMATYMKNIQGKTYYFNEDGSMQIGWKK-VRVWHYFNEDGSMAKDWK 124
Cdd:COG5263  165 GGSAGYGAGKDGATAAAKELVGSAADTYYGGASTYLTGDAGAYGALGLAAGSGAGAKKTGStAGASGTAYGDSGGTAGSG 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 125 KINGSWYHFDKDGYMSDGRRTIGGKTYTFNADGTMVTGWQEIKSGPYTGKWFYYNADGAMATGWAQVKGKWYYFDASGVM 204
Cdd:COG5263  245 LSSLGGSSNALESGGENNQSLAGNGTSYDDAGAAGVDGTGTTGTVGWVDGKWYYFDAGKMVTGWQTINGKWYYFDSDGAM 324

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 205 QTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYVFDDTGAMRKGKLAEGGTVWYFNEDGSMLTGWKQLEEGWYY 284
Cdd:COG5263  325 ATGWQKINGKWYYFDEDGAMAT-------GWVTDDGKWYYLGSDGAMATGWQKIDGKWYYFDSNGAMATGWVKVDGKWYY 397

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446678469 285 FNDqSGASEQGWFSNKGKWYYF-EDGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:COG5263  398 FDS-SGAMATGWLKIDGKWYYFdSDGAMATGWQKIGGKWYYFDSNGAMATGWVKVDGKWYYFDSDGAM 464
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 103-251 2.28e-37

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 141.76  E-value: 2.28e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 103 GWKKVR-VWHYFNEDGSMAKDWKKINGSWYHFdkdgymsdgrrtiggktytfNADGTMVTGWQEIksgpyTGKWFYYNAD 181
Cdd:NF033840 511 GWKQENgMWYFYNTDGSMATGWVQVNGSWYYL--------------------NSNGSMATGWVQV-----NGSWYYLNSN 565

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 182 GAMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKSTEnnwnegWLEENGKRYVFDDTGAM 251
Cdd:NF033840 566 GSMATGWVQVDGSWYYLNDNGSMETGWLQNNGSWYYLNSNGSMKANQ------WFQVGSKWYYVNASGEL 629
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 183-342 2.45e-36

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 139.06  E-value: 2.45e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 183 AMATGWAQVKGKWYYFDASGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYvfddtgamrkgklaeggtv 262
Cdd:NF033840 507 APTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMAT-------GWVQVNGSWY------------------- 560

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 263 wYFNEDGSMLTGWKQLEEGWYYFNDqSGASEQGWFSNKGKWYYF-EDGPMKTG-WLQENKNWYYLQSSGDMAVGKHL--- 337
Cdd:NF033840 561 -YLNSNGSMATGWVQVDGSWYYLND-NGSMETGWLQNNGSWYYLnSNGSMKANqWFQVGSKWYYVNASGELAVNTSIdgy 638


                 ....*...
gi 446678469 338 ---INGKW 342
Cdd:NF033840 639 rvnDNGEW 646
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
41-351 5.01e-33

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 128.06  E-value: 5.01e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  41 KRGWFQGTGYWLYYNEDGSLAIGWKNINGKWYHFDETGMMATYMKNIQGKTYYFNEDGSMQIGWKKVRVWHYFNEDGSMA 120
Cdd:COG5263  141 KKGDTNSANTGYLGDDLGGGTADKGGSAGYGAGKDGATAAAKELVGSAADTYYGGASTYLTGDAGAYGALGLAAGSGAGA 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 121 KDWKKINGSWYHFDKDGYMSDGRRTIGGKTYTFNADGTMVTGWQEIKSGPYTGKWFYYNADGAMATGW-AQVKGKWYYFD 199
Cdd:COG5263  221 KKTGSTAGASGTAYGDSGGTAGSGLSSLGGSSNALESGGENNQSLAGNGTSYDDAGAAGVDGTGTTGTvGWVDGKWYYFD 300

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 200 AsGVMQTGWLKNNNVWYYLNTDGSMKStennwneGWLEENGKRYVFDDTGAMRKGKLAEGGTVWYFNEDGSMLTGWKQLE 279
Cdd:COG5263  301 A-GKMVTGWQTINGKWYYFDSDGAMAT-------GWQKINGKWYYFDEDGAMATGWVTDDGKWYYLGSDGAMATGWQKID 372

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446678469 280 EGWYYFNDqSGASEQGWFSNKGKWYYF-EDGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:COG5263  373 GKWYYFDS-NGAMATGWVKVDGKWYYFdSSGAMATGWLKIDGKWYYFDSDGAMATGWQKIGGKWYYFDSNGAM 444
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
44-351 5.44e-24

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 102.64  E-value: 5.44e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469  44 WFQGTGYWLYYNEDGSLAIGWKNINGKWYHFDETGMMATYMKNIQGKTYYFNEDGSMQIGWKKVRVWHYFNEDGSMAKDW 123
Cdd:COG5263  104 YVVYEGGSVKDYGGGVSDDGDDVVDKTNVAAGGGGKTKKGDTNSANTGYLGDDLGGGTADKGGSAGYGAGKDGATAAAKE 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 124 KKINGSWYHFDKDGYMSDGRRTIGGKTYTFNADGTMVTGWQEIKSGpytgKWFYYNADGAMATGWAQVKGKWYYFDASGV 203
Cdd:COG5263  184 LVGSAADTYYGGASTYLTGDAGAYGALGLAAGSGAGAKKTGSTAGA----SGTAYGDSGGTAGSGLSSLGGSSNALESGG 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 204 MQTGWLKNNNVWYYLNTDGSMKSTENNWN-----------------EGWLEENGKRYVFDDTGAMRKGKLAEGGTVWYFN 266
Cdd:COG5263  260 ENNQSLAGNGTSYDDAGAAGVDGTGTTGTvgwvdgkwyyfdagkmvTGWQTINGKWYYFDSDGAMATGWQKINGKWYYFD 339

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 267 EDGSMLTGWKQLEEGWYYFNDqSGASEQGWFSNKGKWYYF-EDGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTF 345
Cdd:COG5263  340 EDGAMATGWVTDDGKWYYLGS-DGAMATGWQKIDGKWYYFdSNGAMATGWVKVDGKWYYFDSSGAMATGWLKIDGKWYYF 418


                 ....*.
gi 446678469 346 KHNGIM 351
Cdd:COG5263  419 DSDGAM 424
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 234-351 3.11e-23

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 100.93  E-value: 3.11e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 234 GWLEENGkryvfddtgamrkgklaeggtVWYF-NEDGSMLTGWKQLEEGWYYFNdQSGASEQGWFSNKGKWYYF-EDGPM 311
Cdd:NF033840 511 GWKQENG---------------------MWYFyNTDGSMATGWVQVNGSWYYLN-SNGSMATGWVQVNGSWYYLnSNGSM 568

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 446678469 312 KTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:NF033840 569 ATGWVQVDGSWYYLNDNGSMETGWLQNNGSWYYLNSNGSM 608
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 273-351 8.92e-20

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 90.53  E-value: 8.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446678469 273 TGWKQlEEGWYYFNDQSGASEQGWFSNKGKWYYF-EDGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:NF033840 510 TGWKQ-ENGMWYFYNTDGSMATGWVQVNGSWYYLnSNGSMATGWVQVNGSWYYLNSNGSMATGWVQVDGSWYYLNDNGSM 588
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 291-351 3.77e-14

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 73.58  E-value: 3.77e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446678469 291 ASEQGWFSNKGKWYYFE-DGPMKTGWLQENKNWYYLQSSGDMAVGKHLINGKWYTFKHNGIM 351
Cdd:NF033840 507 APTTGWKQENGMWYFYNtDGSMATGWVQVNGSWYYLNSNGSMATGWVQVNGSWYYLNSNGSM 568
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 160-204 8.84e-08

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 47.92  E-value: 8.84e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 446678469  160 VTGWQEIKsgpytGKWFYYNADGAMATGW-AQVKGKWYYFDA-SGVM 204
Cdd:pfam19127   1 VTGWQTIN-----GQTLYFDSDGKQVKGWvVTIDGKWYYFDAdSGEM 42
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 185-226 6.47e-07

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 45.61  E-value: 6.47e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 446678469  185 ATGWAQVKGKWYYFDASGVMQTGWLK-NNNVWYYLNTD-GSMKS 226
Cdd:pfam19127   1 VTGWQTINGQTLYFDSDGKQVKGWVVtIDGKWYYFDADsGEMVT 44
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 142-186 3.86e-06

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 43.30  E-value: 3.86e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 446678469  142 GRRTIGGKTYTFNADGTMVTGWQEIksgpYTGKWFYYNAD-GAMAT 186
Cdd:pfam19127   3 GWQTINGQTLYFDSDGKQVKGWVVT----IDGKWYYFDADsGEMVT 44
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 61-97 5.89e-06

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 42.91  E-value: 5.89e-06
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 446678469   61 AIGWKNINGKWYHFDETGMMAT-YMKNIQGKTYYFNED 97
Cdd:pfam19127   1 VTGWQTINGQTLYFDSDGKQVKgWVVTIDGKWYYFDAD 38
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 111-169 1.01e-05

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 42.51  E-value: 1.01e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446678469  111 HYFNEDGSMAKDWKKINGSWYHFDKDGYMSDGR-RTIGGKTYTFNAD-GTMVT-GWQEIKSG 169
Cdd:TIGR04035   1 YYFDADGKAVTGAQTIDGVTYYFDENGKQVKGDfVTNGGGTYYYDKDsGALVTnRFVTIKDG 62
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 151-206 3.99e-05

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 40.97  E-value: 3.99e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446678469  151 YTFNADGTMVTGWQEIKsgpytGKWFYYNADGAMATG-WAQVKGKWYYFDA-SGVMQT 206
Cdd:TIGR04035   1 YYFDADGKAVTGAQTID-----GVTYYFDENGKQVKGdFVTNGGGTYYYDKdSGALVT 53
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 131-186 5.68e-05

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 40.58  E-value: 5.68e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 446678469  131 YHFDKDGYMSDGRRTIGGKTYTFNADGTMVTG-WQEIKSGPYtgkwFYYNADGAMAT 186
Cdd:TIGR04035   1 YYFDADGKAVTGAQTIDGVTYYFDENGKQVKGdFVTNGGGTY----YYDKDSGALVT 53
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 103-136 7.51e-05

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 39.83  E-value: 7.51e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 446678469  103 GWKKVR-VWHYFNEDGSMAKDW-KKINGSWYHFDKD 136
Cdd:pfam19127   3 GWQTINgQTLYFDSDGKQVKGWvVTIDGKWYYFDAD 38
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 81-122 3.48e-04

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 37.91  E-value: 3.48e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 446678469   81 ATYMKNIQGKTYYFNEDGSMQIGWKKVRV--WHYFNED-GSMAKD 122
Cdd:pfam19127   1 VTGWQTINGQTLYFDSDGKQVKGWVVTIDgkWYYFDADsGEMVTN 45
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 53-97 3.83e-04

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 38.27  E-value: 3.83e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 446678469   53 YYNEDGSLAIGWKNINGKWYHFDETGMMAtymK----NIQGKTYYFNED 97
Cdd:TIGR04035   2 YFDADGKAVTGAQTIDGVTYYFDENGKQV---KgdfvTNGGGTYYYDKD 47
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 49-82 3.04e-03

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 35.21  E-value: 3.04e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 446678469   49 GYWLYYNEDGSLAIGW-KNINGKWYHFDE-TGMMAT 82
Cdd:pfam19127   9 GQTLYFDSDGKQVKGWvVTIDGKWYYFDAdSGEMVT 44
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 196-251 3.47e-03

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 35.57  E-value: 3.47e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446678469  196 YYFDASGVMQTGWLKNNNVWYYLNTDGSM-KstennwnEGWLEENGKRYVFD-DTGAM 251
Cdd:TIGR04035   1 YYFDADGKAVTGAQTIDGVTYYFDENGKQvK-------GDFVTNGGGTYYYDkDSGAL 51
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 72-136 4.23e-03

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 35.19  E-value: 4.23e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446678469   72 YHFDETGMMATYMKNIQGKTYyfnedgsmqigwkkvrvwhYFNEDGSMAK-DWKKINGSWYHFDKD 136
Cdd:TIGR04035   1 YYFDADGKAVTGAQTIDGVTY-------------------YFDENGKQVKgDFVTNGGGTYYYDKD 47
glucan_65_rpt TIGR04035
glucan-binding repeat; This model describes a region of about 63 amino acids that is composed ...
 176-217 4.27e-03

glucan-binding repeat; This model describes a region of about 63 amino acids that is composed of three repeats of a more broadly distributed family of shorter repeats modeled by pfam01473. While the shorter repeats are often associated with choline binding (and therefore with cell wall binding), the longer repeat described here represents a subgroup of repeat sequences associated with glucan binding, as found in a number glycosylhydrolases. Shah, et al. describe a repeat consensus, WYYFDANGKAVTGAQTINGQTLYFDQDGKQVKG, that corresponds to half of the repeat as modeled here and one and a half copies of the repeat as modeled by pfam01473.


Pssm-ID: 274933 [Multi-domain]  Cd Length: 62  Bit Score: 35.19  E-value: 4.27e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 446678469  176 FYYNADGAMATGWAQVKGKWYYFDASGVMQTG-WLKNNNVWYY 217
Cdd:TIGR04035   1 YYFDADGKAVTGAQTIDGVTYYFDENGKQVKGdFVTNGGGTYY 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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