|
Name |
Accession |
Description |
Interval |
E-value |
| NlpA |
COG1464 |
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion ... |
1-270 |
3.81e-130 |
|
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism];
Pssm-ID: 441073 [Multi-domain] Cd Length: 270 Bit Score: 369.44 E-value: 3.81e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 1 MKKVLLSIVSGA-VLLLGACSAGSDKEVKAlDEKKITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDE 79
Cdd:COG1464 1 MKKLLALLLALAlALALAACGSSSAAAAAA-DKKTIKVGATPGPHAEILEVVKPELAKKGIDLEIVEFTDYVQPNEALAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 80 KSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTFPMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVD 159
Cdd:COG1464 80 GEIDANYFQHIPYLDNFNKENGYDLVPVGKTHIEPMGLYSKKYKSLDELPDGATIAIPNDPTNQGRALLLLQKAGLIKLK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 160 PKATEKATAKDVIENPKNLKIVELEASQLPTQLSEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENKDD 239
Cdd:COG1464 160 DGVGLLATVKDITENPKNLKFVELDAAQLPRSLDDVDAAVINGNYALEAGLDPTKDALFLEDKDSPYANIIVVREDDKDD 239
|
250 260 270
....*....|....*....|....*....|.
gi 446679628 240 AVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:COG1464 240 PAIKKLVEAYQSDEVKKFIEEKYKGAVVPAW 270
|
|
| Lipoprotein_9 |
pfam03180 |
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. ... |
35-270 |
1.57e-100 |
|
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. It contains several antigenic members, that may be involved in bacterial virulence. This entry includes the D-methionine binding lipoprotein MetQ, which is the substrate-binding component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. Other members of this family, such as NlpA, have been identified as putative substrate-binding components of ABC transporters. NlpA, is an inner-membrane-anchored lipoprotein that has been shown to have a minor role in methionine import.
Pssm-ID: 427184 Cd Length: 236 Bit Score: 293.02 E-value: 1.57e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 35 ITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTFP 114
Cdd:pfam03180 1 LKVGATPGPHAEILEVAKPLLKKKGLDLEIVEFTDYVQPNTALADGEIDANYFQHLPYLDQFNKEKGLDLVAVGNVHIEP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 115 MGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLSE 194
Cdd:pfam03180 81 MGLYSKKYKSLSELPDGATIAVPNDPSNEGRALLLLQKAGLIKLKDGKGLLATVKDITENPKNLKIKELEAAQLPRALDD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446679628 195 VKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENKDDAVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:pfam03180 161 VDAAVINTNYALEAGLNPKKDALFEEDKDSPYVNIIVVREDDKDDEAVKKLVEAYQSEEVKKFIEKKYGGAVIPAW 236
|
|
| PBP2_lipoprotein_MetQ_like |
cd13526 |
The periplasmic-binding component of ABC-type methionine uptake transporter system and its ... |
34-260 |
1.33e-92 |
|
The periplasmic-binding component of ABC-type methionine uptake transporter system and its related lipoproteins; the type 2 periplasmic-binding protein fold; This family represents the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ) and its related homologs. Members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270244 Cd Length: 228 Bit Score: 272.65 E-value: 1.33e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTF 113
Cdd:cd13526 1 KLKIGVTAGPSADVVEAAKKEAKKKGYELELVVFTDYVAPNEALNDGSIDANFFQHVPFLDQFNKERNGDLVKVGKTVIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 114 PMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13526 81 PIGLYSKKYKSLDELPDGARIAIPNDPSNGARALLLLEDAGLIKLKDGVGLFATVLDITENPKNLEIVEVDAAQLPRSLD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446679628 194 EVKAAAINTNFALGAKLSPAKDSIFREGKD-SPYVNWVVVRTENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13526 161 DVDAAVINGNYAISAGLDPRKDAIFLEDSDaSPYVNVLAVREDNKDDPWVKALVEAYQSEEVRKFLKE 228
|
|
| metQ |
PRK11063 |
D-methionine ABC transporter substrate-binding protein MetQ; |
1-270 |
6.13e-76 |
|
D-methionine ABC transporter substrate-binding protein MetQ;
Pssm-ID: 182939 [Multi-domain] Cd Length: 271 Bit Score: 231.96 E-value: 6.13e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 1 MKKVLLSIVSGAVLLLGACSAGSDKEVKalDEKKITVGVTGGPHEQIFEKVKEVA-AKDGLEIDVKVFNDYVAPNVSLDE 79
Cdd:PRK11063 1 MAFKFKTFAAVGALIGTLALVGCGQDEK--DPNHIKVGVIVGAEQQVAEVAQKVAkEKYGLDVELVTFNDYVLPNEALSK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 80 KSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTFPMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVD 159
Cdd:PRK11063 79 GDIDANAFQHKPYLDQQIKDRGYKLVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 160 PKATEKATAKDVIENPKNLKIVELEASQLPTQL--SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENK 237
Cdd:PRK11063 159 DGVGLLPTVLDIVENPKNLKIVELEAPQLPRSLddAQIALAVINTTYASQIGLTPAKDGIFVEDKDSPYVNLIVAREDNK 238
|
250 260 270
....*....|....*....|....*....|...
gi 446679628 238 DDAVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:PRK11063 239 DAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW 271
|
|
| TIGR00363 |
TIGR00363 |
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for ... |
14-270 |
2.93e-65 |
|
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for lipoprotein signal sequence cleavage. Included in this family is the E. coli hypothetical protein yaeC. About half of the proteins between the noise and trusted cutoffs contain the consensus lipoprotein signature and may belong to this family. [Cell envelope, Other]
Pssm-ID: 129460 Cd Length: 258 Bit Score: 204.36 E-value: 2.93e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 14 LLLGACSAGSDKEVKalDEKKITVGVTGGPHEQIFEKVKEVAA-KDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSY 92
Cdd:TIGR00363 1 LASALVLTGCKQDKK--DPLHIKVGVISGAEQQVAEVAAKVAKeKYGLDVELVEFNDYALPNEAVSKGDLDANAFQHKPY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 93 LDVFKAERNMKLTEVFSTVTFPMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVI 172
Cdd:TIGR00363 79 LDQDAKAKGYKLVAVGNTFVYPLAGYSKKIKNVNELQDGAKVAVPNDPTNLGRALLLLQKQGLIKLKDGNGLLPTVLDIV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 173 ENPKNLKIVELEASQLPTQL--SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENKDDAVVNKLKKAYQ 250
Cdd:TIGR00363 159 ENPKKLNITELETSQLPRALddPKVDLAVINTTYAGQVGLNPQDDGVFVEDKDSPYVNIIVSREDNKDAENVKDFIQSYQ 238
|
250 260
....*....|....*....|
gi 446679628 251 SKEVKEFIEKKFDGSVLPSW 270
Cdd:TIGR00363 239 SEEVYQAAQKHFNGGAVKGW 258
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NlpA |
COG1464 |
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion ... |
1-270 |
3.81e-130 |
|
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism];
Pssm-ID: 441073 [Multi-domain] Cd Length: 270 Bit Score: 369.44 E-value: 3.81e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 1 MKKVLLSIVSGA-VLLLGACSAGSDKEVKAlDEKKITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDE 79
Cdd:COG1464 1 MKKLLALLLALAlALALAACGSSSAAAAAA-DKKTIKVGATPGPHAEILEVVKPELAKKGIDLEIVEFTDYVQPNEALAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 80 KSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTFPMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVD 159
Cdd:COG1464 80 GEIDANYFQHIPYLDNFNKENGYDLVPVGKTHIEPMGLYSKKYKSLDELPDGATIAIPNDPTNQGRALLLLQKAGLIKLK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 160 PKATEKATAKDVIENPKNLKIVELEASQLPTQLSEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENKDD 239
Cdd:COG1464 160 DGVGLLATVKDITENPKNLKFVELDAAQLPRSLDDVDAAVINGNYALEAGLDPTKDALFLEDKDSPYANIIVVREDDKDD 239
|
250 260 270
....*....|....*....|....*....|.
gi 446679628 240 AVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:COG1464 240 PAIKKLVEAYQSDEVKKFIEEKYKGAVVPAW 270
|
|
| Lipoprotein_9 |
pfam03180 |
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. ... |
35-270 |
1.57e-100 |
|
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. It contains several antigenic members, that may be involved in bacterial virulence. This entry includes the D-methionine binding lipoprotein MetQ, which is the substrate-binding component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. Other members of this family, such as NlpA, have been identified as putative substrate-binding components of ABC transporters. NlpA, is an inner-membrane-anchored lipoprotein that has been shown to have a minor role in methionine import.
Pssm-ID: 427184 Cd Length: 236 Bit Score: 293.02 E-value: 1.57e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 35 ITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTFP 114
Cdd:pfam03180 1 LKVGATPGPHAEILEVAKPLLKKKGLDLEIVEFTDYVQPNTALADGEIDANYFQHLPYLDQFNKEKGLDLVAVGNVHIEP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 115 MGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLSE 194
Cdd:pfam03180 81 MGLYSKKYKSLSELPDGATIAVPNDPSNEGRALLLLQKAGLIKLKDGKGLLATVKDITENPKNLKIKELEAAQLPRALDD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446679628 195 VKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENKDDAVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:pfam03180 161 VDAAVINTNYALEAGLNPKKDALFEEDKDSPYVNIIVVREDDKDDEAVKKLVEAYQSEEVKKFIEKKYGGAVIPAW 236
|
|
| PBP2_lipoprotein_MetQ_like |
cd13526 |
The periplasmic-binding component of ABC-type methionine uptake transporter system and its ... |
34-260 |
1.33e-92 |
|
The periplasmic-binding component of ABC-type methionine uptake transporter system and its related lipoproteins; the type 2 periplasmic-binding protein fold; This family represents the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ) and its related homologs. Members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270244 Cd Length: 228 Bit Score: 272.65 E-value: 1.33e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTF 113
Cdd:cd13526 1 KLKIGVTAGPSADVVEAAKKEAKKKGYELELVVFTDYVAPNEALNDGSIDANFFQHVPFLDQFNKERNGDLVKVGKTVIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 114 PMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13526 81 PIGLYSKKYKSLDELPDGARIAIPNDPSNGARALLLLEDAGLIKLKDGVGLFATVLDITENPKNLEIVEVDAAQLPRSLD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446679628 194 EVKAAAINTNFALGAKLSPAKDSIFREGKD-SPYVNWVVVRTENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13526 161 DVDAAVINGNYAISAGLDPRKDAIFLEDSDaSPYVNVLAVREDNKDDPWVKALVEAYQSEEVRKFLKE 228
|
|
| PBP2_lipoprotein_Tp32 |
cd13597 |
The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum ... |
34-268 |
4.89e-89 |
|
The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum binds L-methionine; the type 2 periplasmic-binding protein fold; This group includes the lipoprotein Tp32, a periplasmic component of a methionine uptake transporter system, and its closely related homologs. The Tp32 has both structural and sequential homology to the MetQ family of substrate-binding protein, and thus it belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270315 Cd Length: 236 Bit Score: 264.14 E-value: 4.89e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTF 113
Cdd:cd13597 1 TLKVGATPVPHAEILEFIKPELKKQGIDLEIVEFTDYVQPNTALADGELDANYFQHVPYLESFNKEKGYDLVAVAGVHLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 114 PMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13597 81 PMGLYSKKYKSLEDLPDGATIAIPNDPTNQGRALLLLEEAGLITLKDGAGLTATVKDIVKNPKNLKFKELEAAQLPRSLD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446679628 194 EVKAAAINTNFALGAKLSPAKDSIFREGKD-SPYVNWVVVRTENKDDAVVNKLKKAYQSKEVKEFIEKKFDGSVLP 268
Cdd:cd13597 161 DVDAAVINGNYALEAGLNPKKDALALEDKDnSPYANILVVRKGNEDDPRIKKLAKALQSDEVKDFIEEKYDGAVVP 236
|
|
| PBP2_lipoprotein_IlpA_like |
cd13598 |
Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus and similar ... |
34-260 |
1.66e-86 |
|
Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus and similar lipoproteins; the type 2 periplasmic binding protein fold; This group includes the IlpA protein which has both structural and sequential homology to the MetQ family of substrate-binding protein, and thus belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270316 Cd Length: 227 Bit Score: 257.28 E-value: 1.66e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTF 113
Cdd:cd13598 1 PIKVGVIRGPDAQIWEVVQKVAKEKGLDVELVTFNDYAQPNEALAAGDLDANAFQHKPYLDAQIKARGYKLVIVGNTFVY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 114 PMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13598 81 PIGLYSKKIKSLAELPNGATVAIPNDPSNEGRALLLLQKEGLIKLKDGVGLLATVRDIAENPKKLKIVELDAGQLPRALD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446679628 194 EVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13598 161 DVDLAAINTDYASKAGLTPARDAIAQEDKRSPYANVIAVREDDKDAPWVKTLVQAYQSEEVKAFALK 227
|
|
| metQ |
PRK11063 |
D-methionine ABC transporter substrate-binding protein MetQ; |
1-270 |
6.13e-76 |
|
D-methionine ABC transporter substrate-binding protein MetQ;
Pssm-ID: 182939 [Multi-domain] Cd Length: 271 Bit Score: 231.96 E-value: 6.13e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 1 MKKVLLSIVSGAVLLLGACSAGSDKEVKalDEKKITVGVTGGPHEQIFEKVKEVA-AKDGLEIDVKVFNDYVAPNVSLDE 79
Cdd:PRK11063 1 MAFKFKTFAAVGALIGTLALVGCGQDEK--DPNHIKVGVIVGAEQQVAEVAQKVAkEKYGLDVELVTFNDYVLPNEALSK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 80 KSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTFPMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVD 159
Cdd:PRK11063 79 GDIDANAFQHKPYLDQQIKDRGYKLVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 160 PKATEKATAKDVIENPKNLKIVELEASQLPTQL--SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENK 237
Cdd:PRK11063 159 DGVGLLPTVLDIVENPKNLKIVELEAPQLPRSLddAQIALAVINTTYASQIGLTPAKDGIFVEDKDSPYVNLIVAREDNK 238
|
250 260 270
....*....|....*....|....*....|...
gi 446679628 238 DDAVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:PRK11063 239 DAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW 271
|
|
| PBP2_lipoprotein_GmpC |
cd13596 |
The periplasmic substrate-binding domain of the membrane-associated lipoprotein-9 GmpC; ... |
34-260 |
7.28e-71 |
|
The periplasmic substrate-binding domain of the membrane-associated lipoprotein-9 GmpC; contains the type 2 periplasmic-binding protein fold; This group includes the membrane-associated lipoprotein-9 from Staphylococcus aureus that binds the dipeptide glycylmethionine (GlyMet). The lipoprotein-9 has both structural and sequential homology to the MetQ family of substrate-binding protein. The GlyMet binding protein belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270314 Cd Length: 230 Bit Score: 217.61 E-value: 7.28e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 34 KITVGVTGgPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTF 113
Cdd:cd13596 1 TVKIGVTG-EDTDIWDKIVEEAEEAGIKLELVNFSDYSQPNKALNDGDIDLNAFQHYAYLVQYNSKNNADLTAIGDTVIA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 114 PMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13596 80 PMGIYSKKITSVDELPDGAKIAIPNDPSNLSRALFILQAAGLIKLKKDAGDFPTVNDITENPKNLEIVPVDADQVYRALN 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446679628 194 EVKAAAINTNFALGAKLSPAKDSIFREGKDS----PYVNWVVVRTENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13596 160 DVDAAVINNTFALDAGLDPKKDAIFLEDPSSygskPYINLIAVREEDKDNPLYKKLVETYHDERVQKAVEE 230
|
|
| PBP2_lipoprotein_Gna1946 |
cd13599 |
The membrane-associated lipoprotein Gna1946 from Neisseria meningitidis; the type 2 ... |
34-260 |
3.02e-66 |
|
The membrane-associated lipoprotein Gna1946 from Neisseria meningitidis; the type 2 periplasmic binding protein fold; Gna1946 shares significant structural and sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270317 Cd Length: 228 Bit Score: 205.71 E-value: 3.02e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 34 KITVGVTGGPHEQIFEK-VKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVT 112
Cdd:cd13599 1 TIVIGFTPGPYGDMVKNgVAPYLEKKGYEVKLKEFTDYVQPNNALANGEIDANVFQHKPYLDAFNKENGLDLVGIVQVPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 113 FPMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLK----VDPKateKATAKDVIENPKNLKIVELEASQL 188
Cdd:cd13599 81 PPMGLYSNKHKSLEEVKDGATVAIPNDPSNLARALVMLQDLGWITlkdnIDPL---KASVNDIAENPKNIKIVELEAAQL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446679628 189 PTQLSEVKAAAINTNFALGAKLSPaKDSIFREGKDSPYVNWVVVRTENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13599 158 PRSLDDVDFAAIQGNFAISSGIKL-TSALALEEMTDPYVNVVAVKTADKDKQFAKDVTAAYNSDAFKAYIHA 228
|
|
| TIGR00363 |
TIGR00363 |
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for ... |
14-270 |
2.93e-65 |
|
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for lipoprotein signal sequence cleavage. Included in this family is the E. coli hypothetical protein yaeC. About half of the proteins between the noise and trusted cutoffs contain the consensus lipoprotein signature and may belong to this family. [Cell envelope, Other]
Pssm-ID: 129460 Cd Length: 258 Bit Score: 204.36 E-value: 2.93e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 14 LLLGACSAGSDKEVKalDEKKITVGVTGGPHEQIFEKVKEVAA-KDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSY 92
Cdd:TIGR00363 1 LASALVLTGCKQDKK--DPLHIKVGVISGAEQQVAEVAAKVAKeKYGLDVELVEFNDYALPNEAVSKGDLDANAFQHKPY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 93 LDVFKAERNMKLTEVFSTVTFPMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVI 172
Cdd:TIGR00363 79 LDQDAKAKGYKLVAVGNTFVYPLAGYSKKIKNVNELQDGAKVAVPNDPTNLGRALLLLQKQGLIKLKDGNGLLPTVLDIV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 173 ENPKNLKIVELEASQLPTQL--SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENKDDAVVNKLKKAYQ 250
Cdd:TIGR00363 159 ENPKKLNITELETSQLPRALddPKVDLAVINTTYAGQVGLNPQDDGVFVEDKDSPYVNIIVSREDNKDAENVKDFIQSYQ 238
|
250 260
....*....|....*....|
gi 446679628 251 SKEVKEFIEKKFDGSVLPSW 270
Cdd:TIGR00363 239 SEEVYQAAQKHFNGGAVKGW 258
|
|
| PRK09861 |
PRK09861 |
lipoprotein NlpA; |
1-270 |
3.25e-65 |
|
lipoprotein NlpA;
Pssm-ID: 182119 Cd Length: 272 Bit Score: 204.87 E-value: 3.25e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 1 MKKVLLSIVSGAVLLL-GACSAGSDKevKALDEKKITVGVTGGPHEQIFEKVKEVAA-KDGLEIDVKVFNDYVAPNVSLD 78
Cdd:PRK09861 1 MKLTTHHLRAGAALLLaGILLAGCDQ--SSSDAKHIKVGVINGAEQDVAEVAKKVAKeKYGLDVELVGFSGSLLPNDATN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 79 EKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTFPMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKV 158
Cdd:PRK09861 79 HGELDANVFQHRPFLEQDNQAHGYKLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 159 DPKATEKATAKDVIENPKNLKIVELEASQLPTQLSE--VKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTEN 236
Cdd:PRK09861 159 KEGKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDpkVDVAIISTTYIQQTGLSPVHDSVFIEDKNSPYVNILVAREDN 238
|
250 260 270
....*....|....*....|....*....|....
gi 446679628 237 KDDAVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:PRK09861 239 KNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW 272
|
|
| PBP2_lipoprotein_like_1 |
cd13600 |
Putative periplasmic-binding component of ABC-type methionine uptake transporter system-like; ... |
34-260 |
9.17e-55 |
|
Putative periplasmic-binding component of ABC-type methionine uptake transporter system-like; the type 2 periplasmic binding protein fold; This subgroup shares significant sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270318 Cd Length: 228 Bit Score: 176.37 E-value: 9.17e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLTEVFSTVTF 113
Cdd:cd13600 1 TLKVATNSGPMTEILEYIAAELAPDGITIEPVQVSDYVQANRAVAAGEIDANFFQHQPFMEQFNEANGFELVAVQPIYHW 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 114 PMGVYSKSLKDVKDLKDGDAIAVPNDPTNELRALKLFEKAGVLKVDPKA-TEKATAKDVIENPKNLKIVELEASQLPTQL 192
Cdd:cd13600 81 AFGFYSKKYKSVEDLPDGAKVAIPNDPANQARALLLLQRAGLITLKPGVdPTTATLADIVTNPKNLKFTEVDLLALPRAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446679628 193 SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRTENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13600 161 DDVDLAFGYPSYFDAAGLTPKDGILLEEPDAKRFAIQLVAREDNKDSPKIKKLKEAFTDPRVRKFLET 228
|
|
| UgpB |
COG1653 |
ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport ... |
1-172 |
3.55e-07 |
|
ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport and metabolism];
Pssm-ID: 441259 [Multi-domain] Cd Length: 363 Bit Score: 50.43 E-value: 3.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 1 MKKVLLSIVSGAVLLLGACSAGSDKEVKALDEKKITVGVTGGPHEQIFEKVKEVAAKDGLEIDVKV----FNDYV----- 71
Cdd:COG1653 1 MRRLALALAAALALALAACGGGGSGAAAAAGKVTLTVWHTGGGEAAALEALIKEFEAEHPGIKVEVesvpYDDYRtkllt 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 72 ------APNVsldeksLDVNSYQTKSYldvfkAERN--MKLTEVFSTVTFPMGVYSKSLKDVKDLkDGDAIAVPNDptNE 143
Cdd:COG1653 81 alaagnAPDV------VQVDSGWLAEF-----AAAGalVPLDDLLDDDGLDKDDFLPGALDAGTY-DGKLYGVPFN--TD 146
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446679628 144 LRAL----KLFEKAGvlkVDP--------KATEKATAKDVI 172
Cdd:COG1653 147 TLGLyynkDLFEKAG---LDPpktwdellAAAKKLKAKDGV 184
|
|
| TauA |
COG0715 |
ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion ... |
12-250 |
4.07e-05 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion transport and metabolism];
Pssm-ID: 440479 [Multi-domain] Cd Length: 297 Bit Score: 44.23 E-value: 4.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 12 AVLLLGACSAGSDkevkALDEKKITVGVTGGPH--EQIFEKVKEVAAKDGLEIDVKVFNDYVAPNVSLDEKSLDVNSYqt 89
Cdd:COG0715 5 AALALAACSAAAA----AAEKVTLRLGWLPNTDhaPLYVAKEKGYFKKEGLDVELVEFAGGAAALEALAAGQADFGVA-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 90 kSYLDVFKA-ERNMKLTEVFSTVTF-PMGVYSK---SLKDVKDLKdGDAIAVPNDPTNELRALKLFEKAGVlkvdpkate 164
Cdd:COG0715 79 -GAPPALAArAKGAPVKAVAALSQSgGNALVVRkdsGIKSLADLK-GKKVAVPGGSTSHYLLRALLAKAGL--------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679628 165 katakdvieNPKNLKIVELEASQLPTQLS--EVKAAAINTNFALGAKLSPAKDSIFREGKDSP--YVNWVVVRTE--NKD 238
Cdd:COG0715 148 ---------DPKDVEIVNLPPPDAVAALLagQVDAAVVWEPFESQAEKKGGGRVLADSADLVPgyPGDVLVASEDflEEN 218
|
250
....*....|..
gi 446679628 239 DAVVNKLKKAYQ 250
Cdd:COG0715 219 PEAVKAFLRALL 230
|
|
| |
