|
Name |
Accession |
Description |
Interval |
E-value |
| NlpA |
COG1464 |
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion ... |
1-270 |
7.31e-129 |
|
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism];
Pssm-ID: 441073 [Multi-domain] Cd Length: 270 Bit Score: 366.36 E-value: 7.31e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 1 MKKVLLSIVSGA-VLLLGACSASSDKEVKAlDEKKITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDE 79
Cdd:COG1464 1 MKKLLALLLALAlALALAACGSSSAAAAAA-DKKTIKVGATPGPHAEILEVVKPELAKKGIDLEIVEFTDYVQPNEALAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 80 KSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTFPMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVD 159
Cdd:COG1464 80 GEIDANYFQHIPYLDNFNKENGYDLVPVGKTHIEPMGLYSKKYKSLDELPDGATIAIPNDPTNQGRALLLLQKAGLIKLK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 160 PKATEKATAKDVIENPKNLKIVELEASQLPTQLSEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDD 239
Cdd:COG1464 160 DGVGLLATVKDITENPKNLKFVELDAAQLPRSLDDVDAAVINGNYALEAGLDPTKDALFLEDKDSPYANIIVVREDDKDD 239
|
250 260 270
....*....|....*....|....*....|.
gi 446679636 240 AVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:COG1464 240 PAIKKLVEAYQSDEVKKFIEEKYKGAVVPAW 270
|
|
| Lipoprotein_9 |
pfam03180 |
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. ... |
35-270 |
2.89e-100 |
|
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. It contains several antigenic members, that may be involved in bacterial virulence. This entry includes the D-methionine binding lipoprotein MetQ, which is the substrate-binding component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. Other members of this family, such as NlpA, have been identified as putative substrate-binding components of ABC transporters. NlpA, is an inner-membrane-anchored lipoprotein that has been shown to have a minor role in methionine import.
Pssm-ID: 427184 Cd Length: 236 Bit Score: 292.63 E-value: 2.89e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 35 ITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTFP 114
Cdd:pfam03180 1 LKVGATPGPHAEILEVAKPLLKKKGLDLEIVEFTDYVQPNTALADGEIDANYFQHLPYLDQFNKEKGLDLVAVGNVHIEP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 115 MGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLSE 194
Cdd:pfam03180 81 MGLYSKKYKSLSELPDGATIAVPNDPSNEGRALLLLQKAGLIKLKDGKGLLATVKDITENPKNLKIKELEAAQLPRALDD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446679636 195 VKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:pfam03180 161 VDAAVINTNYALEAGLNPKKDALFEEDKDSPYVNIIVVREDDKDDEAVKKLVEAYQSEEVKKFIEKKYGGAVIPAW 236
|
|
| PBP2_lipoprotein_MetQ_like |
cd13526 |
The periplasmic-binding component of ABC-type methionine uptake transporter system and its ... |
34-260 |
2.06e-91 |
|
The periplasmic-binding component of ABC-type methionine uptake transporter system and its related lipoproteins; the type 2 periplasmic-binding protein fold; This family represents the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ) and its related homologs. Members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270244 Cd Length: 228 Bit Score: 269.57 E-value: 2.06e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTF 113
Cdd:cd13526 1 KLKIGVTAGPSADVVEAAKKEAKKKGYELELVVFTDYVAPNEALNDGSIDANFFQHVPFLDQFNKERNGDLVKVGKTVIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 114 PMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13526 81 PIGLYSKKYKSLDELPDGARIAIPNDPSNGARALLLLEDAGLIKLKDGVGLFATVLDITENPKNLEIVEVDAAQLPRSLD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446679636 194 EVKAAAINTNFALGAKLSPAKDSIFREGKD-SPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13526 161 DVDAAVINGNYAISAGLDPRKDAIFLEDSDaSPYVNVLAVREDNKDDPWVKALVEAYQSEEVRKFLKE 228
|
|
| metQ |
PRK11063 |
D-methionine ABC transporter substrate-binding protein MetQ; |
28-270 |
3.16e-75 |
|
D-methionine ABC transporter substrate-binding protein MetQ;
Pssm-ID: 182939 [Multi-domain] Cd Length: 271 Bit Score: 230.03 E-value: 3.16e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 28 KALDEKKITVGVTGGPHEQIFEKVKEVA-AKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAE 106
Cdd:PRK11063 26 DEKDPNHIKVGVIVGAEQQVAEVAQKVAkEKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQIKDRGYKLVA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 107 VFSTVTFPMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEAS 186
Cdd:PRK11063 106 VGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDGVGLLPTVLDIVENPKNLKIVELEAP 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 187 QLPTQL--SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEKKFDG 264
Cdd:PRK11063 186 QLPRSLddAQIALAVINTTYASQIGLTPAKDGIFVEDKDSPYVNLIVAREDNKDAENVKKFVQAYQSDEVYEAANKVFNG 265
|
....*.
gi 446679636 265 SVLPSW 270
Cdd:PRK11063 266 GAVKGW 271
|
|
| TIGR00363 |
TIGR00363 |
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for ... |
12-270 |
3.72e-65 |
|
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for lipoprotein signal sequence cleavage. Included in this family is the E. coli hypothetical protein yaeC. About half of the proteins between the noise and trusted cutoffs contain the consensus lipoprotein signature and may belong to this family. [Cell envelope, Other]
Pssm-ID: 129460 Cd Length: 258 Bit Score: 203.98 E-value: 3.72e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 12 AVLLLGACSASSDkevkalDEKKITVGVTGGPHEQIFEKVKEVAA-KDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTK 90
Cdd:TIGR00363 3 SALVLTGCKQDKK------DPLHIKVGVISGAEQQVAEVAAKVAKeKYGLDVELVEFNDYALPNEAVSKGDLDANAFQHK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 91 SYLDVFKAERNMKLAEVFSTVTFPMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKD 170
Cdd:TIGR00363 77 PYLDQDAKAKGYKLVAVGNTFVYPLAGYSKKIKNVNELQDGAKVAVPNDPTNLGRALLLLQKQGLIKLKDGNGLLPTVLD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 171 VIENPKNLKIVELEASQLPTQL--SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDDAVVNKLKKA 248
Cdd:TIGR00363 157 IVENPKKLNITELETSQLPRALddPKVDLAVINTTYAGQVGLNPQDDGVFVEDKDSPYVNIIVSREDNKDAENVKDFIQS 236
|
250 260
....*....|....*....|..
gi 446679636 249 YQSKEVKEFIEKKFDGSVLPSW 270
Cdd:TIGR00363 237 YQSEEVYQAAQKHFNGGAVKGW 258
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NlpA |
COG1464 |
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion ... |
1-270 |
7.31e-129 |
|
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism];
Pssm-ID: 441073 [Multi-domain] Cd Length: 270 Bit Score: 366.36 E-value: 7.31e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 1 MKKVLLSIVSGA-VLLLGACSASSDKEVKAlDEKKITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDE 79
Cdd:COG1464 1 MKKLLALLLALAlALALAACGSSSAAAAAA-DKKTIKVGATPGPHAEILEVVKPELAKKGIDLEIVEFTDYVQPNEALAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 80 KSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTFPMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVD 159
Cdd:COG1464 80 GEIDANYFQHIPYLDNFNKENGYDLVPVGKTHIEPMGLYSKKYKSLDELPDGATIAIPNDPTNQGRALLLLQKAGLIKLK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 160 PKATEKATAKDVIENPKNLKIVELEASQLPTQLSEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDD 239
Cdd:COG1464 160 DGVGLLATVKDITENPKNLKFVELDAAQLPRSLDDVDAAVINGNYALEAGLDPTKDALFLEDKDSPYANIIVVREDDKDD 239
|
250 260 270
....*....|....*....|....*....|.
gi 446679636 240 AVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:COG1464 240 PAIKKLVEAYQSDEVKKFIEEKYKGAVVPAW 270
|
|
| Lipoprotein_9 |
pfam03180 |
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. ... |
35-270 |
2.89e-100 |
|
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. It contains several antigenic members, that may be involved in bacterial virulence. This entry includes the D-methionine binding lipoprotein MetQ, which is the substrate-binding component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. Other members of this family, such as NlpA, have been identified as putative substrate-binding components of ABC transporters. NlpA, is an inner-membrane-anchored lipoprotein that has been shown to have a minor role in methionine import.
Pssm-ID: 427184 Cd Length: 236 Bit Score: 292.63 E-value: 2.89e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 35 ITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTFP 114
Cdd:pfam03180 1 LKVGATPGPHAEILEVAKPLLKKKGLDLEIVEFTDYVQPNTALADGEIDANYFQHLPYLDQFNKEKGLDLVAVGNVHIEP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 115 MGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLSE 194
Cdd:pfam03180 81 MGLYSKKYKSLSELPDGATIAVPNDPSNEGRALLLLQKAGLIKLKDGKGLLATVKDITENPKNLKIKELEAAQLPRALDD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446679636 195 VKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:pfam03180 161 VDAAVINTNYALEAGLNPKKDALFEEDKDSPYVNIIVVREDDKDDEAVKKLVEAYQSEEVKKFIEKKYGGAVIPAW 236
|
|
| PBP2_lipoprotein_MetQ_like |
cd13526 |
The periplasmic-binding component of ABC-type methionine uptake transporter system and its ... |
34-260 |
2.06e-91 |
|
The periplasmic-binding component of ABC-type methionine uptake transporter system and its related lipoproteins; the type 2 periplasmic-binding protein fold; This family represents the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ) and its related homologs. Members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270244 Cd Length: 228 Bit Score: 269.57 E-value: 2.06e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTF 113
Cdd:cd13526 1 KLKIGVTAGPSADVVEAAKKEAKKKGYELELVVFTDYVAPNEALNDGSIDANFFQHVPFLDQFNKERNGDLVKVGKTVIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 114 PMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13526 81 PIGLYSKKYKSLDELPDGARIAIPNDPSNGARALLLLEDAGLIKLKDGVGLFATVLDITENPKNLEIVEVDAAQLPRSLD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446679636 194 EVKAAAINTNFALGAKLSPAKDSIFREGKD-SPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13526 161 DVDAAVINGNYAISAGLDPRKDAIFLEDSDaSPYVNVLAVREDNKDDPWVKALVEAYQSEEVRKFLKE 228
|
|
| PBP2_lipoprotein_Tp32 |
cd13597 |
The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum ... |
34-268 |
3.72e-89 |
|
The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum binds L-methionine; the type 2 periplasmic-binding protein fold; This group includes the lipoprotein Tp32, a periplasmic component of a methionine uptake transporter system, and its closely related homologs. The Tp32 has both structural and sequential homology to the MetQ family of substrate-binding protein, and thus it belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270315 Cd Length: 236 Bit Score: 264.14 E-value: 3.72e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTF 113
Cdd:cd13597 1 TLKVGATPVPHAEILEFIKPELKKQGIDLEIVEFTDYVQPNTALADGELDANYFQHVPYLESFNKEKGYDLVAVAGVHLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 114 PMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13597 81 PMGLYSKKYKSLEDLPDGATIAIPNDPTNQGRALLLLEEAGLITLKDGAGLTATVKDIVKNPKNLKFKELEAAQLPRSLD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446679636 194 EVKAAAINTNFALGAKLSPAKDSIFREGKD-SPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEKKFDGSVLP 268
Cdd:cd13597 161 DVDAAVINGNYALEAGLNPKKDALALEDKDnSPYANILVVRKGNEDDPRIKKLAKALQSDEVKDFIEEKYDGAVVP 236
|
|
| PBP2_lipoprotein_IlpA_like |
cd13598 |
Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus and similar ... |
34-260 |
1.28e-86 |
|
Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus and similar lipoproteins; the type 2 periplasmic binding protein fold; This group includes the IlpA protein which has both structural and sequential homology to the MetQ family of substrate-binding protein, and thus belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270316 Cd Length: 227 Bit Score: 257.66 E-value: 1.28e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTF 113
Cdd:cd13598 1 PIKVGVIRGPDAQIWEVVQKVAKEKGLDVELVTFNDYAQPNEALAAGDLDANAFQHKPYLDAQIKARGYKLVIVGNTFVY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 114 PMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13598 81 PIGLYSKKIKSLAELPNGATVAIPNDPSNEGRALLLLQKEGLIKLKDGVGLLATVRDIAENPKKLKIVELDAGQLPRALD 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446679636 194 EVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13598 161 DVDLAAINTDYASKAGLTPARDAIAQEDKRSPYANVIAVREDDKDAPWVKTLVQAYQSEEVKAFALK 227
|
|
| metQ |
PRK11063 |
D-methionine ABC transporter substrate-binding protein MetQ; |
28-270 |
3.16e-75 |
|
D-methionine ABC transporter substrate-binding protein MetQ;
Pssm-ID: 182939 [Multi-domain] Cd Length: 271 Bit Score: 230.03 E-value: 3.16e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 28 KALDEKKITVGVTGGPHEQIFEKVKEVA-AKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAE 106
Cdd:PRK11063 26 DEKDPNHIKVGVIVGAEQQVAEVAQKVAkEKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQIKDRGYKLVA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 107 VFSTVTFPMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEAS 186
Cdd:PRK11063 106 VGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDGVGLLPTVLDIVENPKNLKIVELEAP 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 187 QLPTQL--SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEKKFDG 264
Cdd:PRK11063 186 QLPRSLddAQIALAVINTTYASQIGLTPAKDGIFVEDKDSPYVNLIVAREDNKDAENVKKFVQAYQSDEVYEAANKVFNG 265
|
....*.
gi 446679636 265 SVLPSW 270
Cdd:PRK11063 266 GAVKGW 271
|
|
| PBP2_lipoprotein_GmpC |
cd13596 |
The periplasmic substrate-binding domain of the membrane-associated lipoprotein-9 GmpC; ... |
34-260 |
2.47e-69 |
|
The periplasmic substrate-binding domain of the membrane-associated lipoprotein-9 GmpC; contains the type 2 periplasmic-binding protein fold; This group includes the membrane-associated lipoprotein-9 from Staphylococcus aureus that binds the dipeptide glycylmethionine (GlyMet). The lipoprotein-9 has both structural and sequential homology to the MetQ family of substrate-binding protein. The GlyMet binding protein belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270314 Cd Length: 230 Bit Score: 213.76 E-value: 2.47e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 34 KITVGVTGgPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTF 113
Cdd:cd13596 1 TVKIGVTG-EDTDIWDKIVEEAEEAGIKLELVNFSDYSQPNKALNDGDIDLNAFQHYAYLVQYNSKNNADLTAIGDTVIA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 114 PMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKDVIENPKNLKIVELEASQLPTQLS 193
Cdd:cd13596 80 PMGIYSKKITSVDELPDGAKIAIPNDPSNLSRALFILQAAGLIKLKKDAGDFPTVNDITENPKNLEIVPVDADQVYRALN 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446679636 194 EVKAAAINTNFALGAKLSPAKDSIFREGKDS----PYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13596 160 DVDAAVINNTFALDAGLDPKKDAIFLEDPSSygskPYINLIAVREEDKDNPLYKKLVETYHDERVQKAVEE 230
|
|
| TIGR00363 |
TIGR00363 |
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for ... |
12-270 |
3.72e-65 |
|
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for lipoprotein signal sequence cleavage. Included in this family is the E. coli hypothetical protein yaeC. About half of the proteins between the noise and trusted cutoffs contain the consensus lipoprotein signature and may belong to this family. [Cell envelope, Other]
Pssm-ID: 129460 Cd Length: 258 Bit Score: 203.98 E-value: 3.72e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 12 AVLLLGACSASSDkevkalDEKKITVGVTGGPHEQIFEKVKEVAA-KDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTK 90
Cdd:TIGR00363 3 SALVLTGCKQDKK------DPLHIKVGVISGAEQQVAEVAAKVAKeKYGLDVELVEFNDYALPNEAVSKGDLDANAFQHK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 91 SYLDVFKAERNMKLAEVFSTVTFPMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKATEKATAKD 170
Cdd:TIGR00363 77 PYLDQDAKAKGYKLVAVGNTFVYPLAGYSKKIKNVNELQDGAKVAVPNDPTNLGRALLLLQKQGLIKLKDGNGLLPTVLD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 171 VIENPKNLKIVELEASQLPTQL--SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDDAVVNKLKKA 248
Cdd:TIGR00363 157 IVENPKKLNITELETSQLPRALddPKVDLAVINTTYAGQVGLNPQDDGVFVEDKDSPYVNIIVSREDNKDAENVKDFIQS 236
|
250 260
....*....|....*....|..
gi 446679636 249 YQSKEVKEFIEKKFDGSVLPSW 270
Cdd:TIGR00363 237 YQSEEVYQAAQKHFNGGAVKGW 258
|
|
| PRK09861 |
PRK09861 |
lipoprotein NlpA; |
1-270 |
2.60e-64 |
|
lipoprotein NlpA;
Pssm-ID: 182119 Cd Length: 272 Bit Score: 202.56 E-value: 2.60e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 1 MKKVLLSIVSGAVLLL-GACSASSDKevKALDEKKITVGVTGGPHEQIFEKVKEVAA-KDGLEIDIKVFNDYVAPNVSLD 78
Cdd:PRK09861 1 MKLTTHHLRAGAALLLaGILLAGCDQ--SSSDAKHIKVGVINGAEQDVAEVAKKVAKeKYGLDVELVGFSGSLLPNDATN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 79 EKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTFPMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKV 158
Cdd:PRK09861 79 HGELDANVFQHRPFLEQDNQAHGYKLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 159 DPKATEKATAKDVIENPKNLKIVELEASQLPTQLSE--VKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNEN 236
Cdd:PRK09861 159 KEGKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDpkVDVAIISTTYIQQTGLSPVHDSVFIEDKNSPYVNILVAREDN 238
|
250 260 270
....*....|....*....|....*....|....
gi 446679636 237 KDDAVVNKLKKAYQSKEVKEFIEKKFDGSVLPSW 270
Cdd:PRK09861 239 KNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW 272
|
|
| PBP2_lipoprotein_Gna1946 |
cd13599 |
The membrane-associated lipoprotein Gna1946 from Neisseria meningitidis; the type 2 ... |
34-260 |
6.32e-64 |
|
The membrane-associated lipoprotein Gna1946 from Neisseria meningitidis; the type 2 periplasmic binding protein fold; Gna1946 shares significant structural and sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270317 Cd Length: 228 Bit Score: 199.93 E-value: 6.32e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 34 KITVGVTGGPHEQIFEK-VKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVT 112
Cdd:cd13599 1 TIVIGFTPGPYGDMVKNgVAPYLEKKGYEVKLKEFTDYVQPNNALANGEIDANVFQHKPYLDAFNKENGLDLVGIVQVPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 113 FPMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLK----VDPKateKATAKDVIENPKNLKIVELEASQL 188
Cdd:cd13599 81 PPMGLYSNKHKSLEEVKDGATVAIPNDPSNLARALVMLQDLGWITlkdnIDPL---KASVNDIAENPKNIKIVELEAAQL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446679636 189 PTQLSEVKAAAINTNFALGAKLSPaKDSIFREGKDSPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13599 158 PRSLDDVDFAAIQGNFAISSGIKL-TSALALEEMTDPYVNVVAVKTADKDKQFAKDVTAAYNSDAFKAYIHA 228
|
|
| PBP2_lipoprotein_like_1 |
cd13600 |
Putative periplasmic-binding component of ABC-type methionine uptake transporter system-like; ... |
34-260 |
4.70e-53 |
|
Putative periplasmic-binding component of ABC-type methionine uptake transporter system-like; the type 2 periplasmic binding protein fold; This subgroup shares significant sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270318 Cd Length: 228 Bit Score: 172.13 E-value: 4.70e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 34 KITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQTKSYLDVFKAERNMKLAEVFSTVTF 113
Cdd:cd13600 1 TLKVATNSGPMTEILEYIAAELAPDGITIEPVQVSDYVQANRAVAAGEIDANFFQHQPFMEQFNEANGFELVAVQPIYHW 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 114 PMGVYSKDIKDVKDLKEGDAIAVPNDPTNELRALKLFEKAGVLKVDPKA-TEKATAKDVIENPKNLKIVELEASQLPTQL 192
Cdd:cd13600 81 AFGFYSKKYKSVEDLPDGAKVAIPNDPANQARALLLLQRAGLITLKPGVdPTTATLADIVTNPKNLKFTEVDLLALPRAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446679636 193 SEVKAAAINTNFALGAKLSPAKDSIFREGKDSPYVNWVVVRNENKDDAVVNKLKKAYQSKEVKEFIEK 260
Cdd:cd13600 161 DDVDLAFGYPSYFDAAGLTPKDGILLEEPDAKRFAIQLVAREDNKDSPKIKKLKEAFTDPRVRKFLET 228
|
|
| TauA |
COG0715 |
ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion ... |
12-250 |
2.70e-06 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion transport and metabolism];
Pssm-ID: 440479 [Multi-domain] Cd Length: 297 Bit Score: 47.69 E-value: 2.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 12 AVLLLGACSASSDkevkALDEKKITVGVTGGPH--EQIFEKVKEVAAKDGLEIDIKVFNDYVAPNVSLDEKSLDVNSYQT 89
Cdd:COG0715 5 AALALAACSAAAA----AAEKVTLRLGWLPNTDhaPLYVAKEKGYFKKEGLDVELVEFAGGAAALEALAAGQADFGVAGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 90 KSYLDVFKAERNMKLAEVFSTVTfPMGVYSK---DIKDVKDLKeGDAIAVPNDPTNELRALKLFEKAGVlkvdpkateka 166
Cdd:COG0715 81 PPALAARAKGAPVKAVAALSQSG-GNALVVRkdsGIKSLADLK-GKKVAVPGGSTSHYLLRALLAKAGL----------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446679636 167 takdvieNPKNLKIVELEASQLPTQLS--EVKAAAINTNFALGAKLSPAKDSIFREGKDSP--YVNWVVVRNE--NKDDA 240
Cdd:COG0715 148 -------DPKDVEIVNLPPPDAVAALLagQVDAAVVWEPFESQAEKKGGGRVLADSADLVPgyPGDVLVASEDflEENPE 220
|
250
....*....|
gi 446679636 241 VVNKLKKAYQ 250
Cdd:COG0715 221 AVKAFLRALL 230
|
|
| UgpB |
COG1653 |
ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport ... |
1-70 |
1.35e-05 |
|
ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport and metabolism];
Pssm-ID: 441259 [Multi-domain] Cd Length: 363 Bit Score: 45.81 E-value: 1.35e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446679636 1 MKKVLLSIVSGAVLLLGACSASSDKEVKALDEKKITVGVTGGPHEQIFEKVKEVAAKDGLEIDIKV----FNDY 70
Cdd:COG1653 1 MRRLALALAAALALALAACGGGGSGAAAAAGKVTLTVWHTGGGEAAALEALIKEFEAEHPGIKVEVesvpYDDY 74
|
|
| |
