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Conserved domains on  [gi|446681103|ref|WP_000758449|]
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MULTISPECIES: mechanosensitive ion channel protein [Bacillus]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 1904476)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.1.-
Gene Ontology:  GO:0008080
PubMed:  9175471|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArgA super family cl43364
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 7-125 2.64e-05

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


The actual alignment was detected with superfamily member COG1246:

Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 41.52  E-value: 2.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446681103   7 ATKEDVERLHSFFgqankKDDKINELYAQFMILEEAEEIRAVIGYEQ-SEENALIRSCLFTPHVDKQ---TFLyfFEMFL 82
Cdd:COG1246    6 ATPDDVPAILELI-----RPYALEEEIGEFWVAEEDGEIVGCAALHPlDEDLAELRSLAVHPDYRGRgigRRL--LEALL 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 446681103  83 QYMKEKNIRQLYLLTNHPqSITIFQFFDFVTIEREKVPEGIRQ 125
Cdd:COG1246   79 AEARELGLKRLFLLTTSA-AIHFYEKLGFEEIDKEDLPYAKVW 120
 
Name Accession Description Interval E-value
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 7-125 2.64e-05

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 41.52  E-value: 2.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446681103   7 ATKEDVERLHSFFgqankKDDKINELYAQFMILEEAEEIRAVIGYEQ-SEENALIRSCLFTPHVDKQ---TFLyfFEMFL 82
Cdd:COG1246    6 ATPDDVPAILELI-----RPYALEEEIGEFWVAEEDGEIVGCAALHPlDEDLAELRSLAVHPDYRGRgigRRL--LEALL 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 446681103  83 QYMKEKNIRQLYLLTNHPqSITIFQFFDFVTIEREKVPEGIRQ 125
Cdd:COG1246   79 AEARELGLKRLFLLTTSA-AIHFYEKLGFEEIDKEDLPYAKVW 120
 
Name Accession Description Interval E-value
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 7-125 2.64e-05

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 41.52  E-value: 2.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446681103   7 ATKEDVERLHSFFgqankKDDKINELYAQFMILEEAEEIRAVIGYEQ-SEENALIRSCLFTPHVDKQ---TFLyfFEMFL 82
Cdd:COG1246    6 ATPDDVPAILELI-----RPYALEEEIGEFWVAEEDGEIVGCAALHPlDEDLAELRSLAVHPDYRGRgigRRL--LEALL 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 446681103  83 QYMKEKNIRQLYLLTNHPqSITIFQFFDFVTIEREKVPEGIRQ 125
Cdd:COG1246   79 AEARELGLKRLFLLTTSA-AIHFYEKLGFEEIDKEDLPYAKVW 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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