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Conserved domains on  [gi|446683342|ref|WP_000760688|]
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MULTISPECIES: GntR family transcriptional regulator YdcR [Salmonella]

Protein Classification

PLP-dependent aminotransferase family protein( domain architecture ID 11439382)

pyridoxal phosphate (PLP)-dependent aminotransferase family protein may catalyze the reversible exchange of an amino group from one molecule with a keto group from another molecule

CATH:  3.40.640.10
Gene Ontology:  GO:0030170
PubMed:  17109392
SCOP:  4000670

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
1-468 0e+00

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


:

Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 522.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   1 MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHPVCRSVATAAH 80
Cdd:COG1167   11 GPLYLQLADALREAILSGRLPPGDRLPSSRELAAQLGVSRSTVVRAYEELEAEGLIESRPGSGTFVAARLPAPAPAPRAA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  81 VIRDEAVdintyIFEMLQASRDtsVVPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQ 160
Cdd:COG1167   91 AAVAAPA-----LRRLLEAAPG--VIDLGSGAPDPDLFPLAALRRALRRALRRLPPALLGYGDPQGLPELREAIARYLAR 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 161 QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDvKEGIDLMALEQALQEYPV 240
Cdd:COG1167  164 RGVPASPDQILITSGAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVD-EDGLDLDALEAALRRHRP 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 241 KACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCLVPGFRI 320
Cdd:COG1167  243 RAVYVTPSHQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAPGRVIYIGSFSKTLAPGLRL 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 321 GW-VAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGY 399
Cdd:COG1167  323 GYlVAPGRLIERLARLKRATDLGTSPLTQLALAEFLESGHYDRHLRRLRREYRARRDLLLAALARHLPDGLRVTGPPGGL 402
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446683342 400 FLWLELPEQLDAGELSAKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREML 468
Cdd:COG1167  403 HLWLELPEGVDAEALAAAALARGILVAPGSAFSADGPPRNGLRLGFGAPSEEELEEALRRLAELLRELA 471
 
Name Accession Description Interval E-value
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
1-468 0e+00

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 522.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   1 MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHPVCRSVATAAH 80
Cdd:COG1167   11 GPLYLQLADALREAILSGRLPPGDRLPSSRELAAQLGVSRSTVVRAYEELEAEGLIESRPGSGTFVAARLPAPAPAPRAA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  81 VIRDEAVdintyIFEMLQASRDtsVVPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQ 160
Cdd:COG1167   91 AAVAAPA-----LRRLLEAAPG--VIDLGSGAPDPDLFPLAALRRALRRALRRLPPALLGYGDPQGLPELREAIARYLAR 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 161 QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDvKEGIDLMALEQALQEYPV 240
Cdd:COG1167  164 RGVPASPDQILITSGAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVD-EDGLDLDALEAALRRHRP 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 241 KACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCLVPGFRI 320
Cdd:COG1167  243 RAVYVTPSHQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAPGRVIYIGSFSKTLAPGLRL 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 321 GW-VAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGY 399
Cdd:COG1167  323 GYlVAPGRLIERLARLKRATDLGTSPLTQLALAEFLESGHYDRHLRRLRREYRARRDLLLAALARHLPDGLRVTGPPGGL 402
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446683342 400 FLWLELPEQLDAGELSAKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREML 468
Cdd:COG1167  403 HLWLELPEGVDAEALAAAALARGILVAPGSAFSADGPPRNGLRLGFGAPSEEELEEALRRLAELLRELA 471
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
106-446 1.57e-71

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 230.31  E-value: 1.57e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 106 VPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSvienLPPGNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSL 184
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLGYY----PDPGLPELREAIAEWLGRRgGVDVPPEEIVVTNGAQEALSLLL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 185 QAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLM-ALEQALQEYPVKACWLmTNSQNPLGFTLSAEKKA 263
Cdd:cd00609   77 RALLNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDlELLEAAKTPKTKLLYL-NNPNNPTGAVLSEEELE 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 264 RLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCL-VPGFRIGWVAGGSH--ARQIQRLQLMST 340
Cdd:cd00609  156 ELAELAKKHGILIISDEAYAELVYDGEPPPALALLDAYERVIVLRSFSKTFgLPGLRIGYLIAPPEelLERLKKLLPYTT 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 341 LSTSSPMQLALVDYLSTRryDAHLRRLRRQLAERKQQAWQTLLRHLPaeVKIHHNDSGYFLWLELPEQLDAGELSAKALE 420
Cdd:cd00609  236 SGPSTLSQAAAAAALDDG--EEHLEELRERYRRRRDALLEALKELGP--LVVVKPSGGFFLWLDLPEGDDEEFLERLLLE 311
                        330       340
                 ....*....|....*....|....*.
gi 446683342 421 HLISIAPGKMFSTSGAwtRFFRFNTA 446
Cdd:cd00609  312 AGVVVRPGSAFGEGGE--GFVRLSFA 335
PRK15481 PRK15481
transcriptional regulatory protein PtsJ; Provisional
9-411 1.76e-36

transcriptional regulatory protein PtsJ; Provisional


Pssm-ID: 185378 [Multi-domain]  Cd Length: 431  Bit Score: 139.41  E-value: 1.76e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   9 EQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYV--APHPVCRSVATAAHVIRDea 86
Cdd:PRK15481  12 DSIRQLIQAGRLRPGDSLPPVRELASELGVNRNTVAAAYKRLVTAGLAQSQGRNGTVIrgSPSPVALEGGDPGTPLHD-- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  87 vdintyifemlqasrdtsvvpFASAFPDPRLfpLPQLNRSLAQVSKTATAMSVienlPPGNAELRyAIARRYAQQGITVs 166
Cdd:PRK15481  90 ---------------------LAGGNPDPQR--LPDLSRYFARLSRTPRLYGD----APVSPELH-AWAARWLRDDCPV- 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 167 PDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVkEGIDLMALEQALQEyPVKACWLM 246
Cdd:PRK15481 141 AFEIDLTSGAIDAIERLLCAHLLPGDSVAVEDPCFLSSINMLRYAGFSASPVSVDA-EGMQPEKLERALAQ-GARAVILT 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 247 TNSQNPLGFTLSAEKKARLVALLTHH-NVMLIEDDVYSELYFGR-EKPLPAKA--WdrddTVLHcsSFSKCLVPGFRIGW 322
Cdd:PRK15481 219 PRAHNPTGCSLSARRAAALRNLLARYpQVLVIIDDHFALLSSSPyHSVIPQTTqrW----ALIR--SVSKALGPDLRLAF 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 323 VAGGSHARQIQRLQLMS-TLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHlpaevKIHHNDS--GY 399
Cdd:PRK15481 293 VASDSATSARLRLRLNSgTQWVSHLLQDLVYACLTDPEYQARLAQARLFYAQRRQKLARALQQY-----GIAIPSPgdGL 367
                        410
                 ....*....|..
gi 446683342 400 FLWLELPEQLDA 411
Cdd:PRK15481 368 NLWLPLDTDSQA 379
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
114-448 4.14e-28

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 114.32  E-value: 4.14e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  114 DPRLFPLPqlnrSLAQVSKTATAMSVIENLPP--GNAELRYAIARRY-AQQGITVSP-DEIVITAGALEALNLSLQAVTA 189
Cdd:pfam00155  10 EYLGDTLP----AVAKAEKDALAGGTRNLYGPtdGHPELREALAKFLgRSPVLKLDReAAVVFGSGAGANIEALIFLLAN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  190 PGDWVVVENPCFYGALQALERLRLKALSIPTDVKEG--IDLMALEQALQEypvKACWLMTNS-QNPLGFTLSAEKKARLV 266
Cdd:pfam00155  86 PGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSNDfhLDFDALEAALKE---KPKVVLHTSpHNPTGTVATLEELEKLL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  267 ALLTHHNVMLIEDDVYSELYFGREKPLPAKAW-DRDDTVLHCSSFSKCL-VPGFRIGWVAGGSHARQIQRlQLMSTLSTS 344
Cdd:pfam00155 163 DLAKEHNILLLVDEAYAGFVFGSPDAVATRALlAEGPNLLVVGSFSKAFgLAGWRVGYILGNAAVISQLR-KLARPFYSS 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  345 SPMQLALVDYLSTR-RYDAHLRRLRRQLAERKQQawqtLLRHLPAEVKIH-HNDSGYFLWLELPEqLDAGELSAKAL-EH 421
Cdd:pfam00155 242 THLQAAAAAALSDPlLVASELEEMRQRIKERRDY----LRDGLQAAGLSVlPSQAGFFLLTGLDP-ETAKELAQVLLeEV 316
                         330       340
                  ....*....|....*....|....*..
gi 446683342  422 LISIAPGKMFSTSGawtrFFRFNTAWH 448
Cdd:pfam00155 317 GVYVTPGSSPGVPG----WLRITVAGG 339
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
145-324 7.09e-18

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 85.47  E-value: 7.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  145 PGNAELRYAIARRYAQQGITV-SPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALQALERLRLKALSIPTD 221
Cdd:TIGR01265  73 VGALAAREAVAEYLSSDLPGKlTADDVVLTSGCSQAIEICIEALANPGANILVPRPGFplYDTRAAFSGLEVRLYDLLPE 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  222 VKEGIDLMALEQALQEYPVkaCWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRD 301
Cdd:TIGR01265 153 KDWEIDLDGLESLADEKTV--AIVVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPMASFASI 230
                         170       180
                  ....*....|....*....|....
gi 446683342  302 DTVLHCSSFSK-CLVPGFRIGWVA 324
Cdd:TIGR01265 231 VPVLSLGGISKrWVVPGWRLGWII 254
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
7-66 1.94e-13

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 64.90  E-value: 1.94e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342     7 LAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYV 66
Cdd:smart00345   1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
 
Name Accession Description Interval E-value
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
1-468 0e+00

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 522.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   1 MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHPVCRSVATAAH 80
Cdd:COG1167   11 GPLYLQLADALREAILSGRLPPGDRLPSSRELAAQLGVSRSTVVRAYEELEAEGLIESRPGSGTFVAARLPAPAPAPRAA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  81 VIRDEAVdintyIFEMLQASRDtsVVPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQ 160
Cdd:COG1167   91 AAVAAPA-----LRRLLEAAPG--VIDLGSGAPDPDLFPLAALRRALRRALRRLPPALLGYGDPQGLPELREAIARYLAR 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 161 QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDvKEGIDLMALEQALQEYPV 240
Cdd:COG1167  164 RGVPASPDQILITSGAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVD-EDGLDLDALEAALRRHRP 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 241 KACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCLVPGFRI 320
Cdd:COG1167  243 RAVYVTPSHQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAPGRVIYIGSFSKTLAPGLRL 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 321 GW-VAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGY 399
Cdd:COG1167  323 GYlVAPGRLIERLARLKRATDLGTSPLTQLALAEFLESGHYDRHLRRLRREYRARRDLLLAALARHLPDGLRVTGPPGGL 402
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446683342 400 FLWLELPEQLDAGELSAKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREML 468
Cdd:COG1167  403 HLWLELPEGVDAEALAAAALARGILVAPGSAFSADGPPRNGLRLGFGAPSEEELEEALRRLAELLRELA 471
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
106-446 1.57e-71

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 230.31  E-value: 1.57e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 106 VPFASAFPDPRLFPLPQLNRSLAQVSKTATAMSvienLPPGNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSL 184
Cdd:cd00609    1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLGYY----PDPGLPELREAIAEWLGRRgGVDVPPEEIVVTNGAQEALSLLL 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 185 QAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLM-ALEQALQEYPVKACWLmTNSQNPLGFTLSAEKKA 263
Cdd:cd00609   77 RALLNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDlELLEAAKTPKTKLLYL-NNPNNPTGAVLSEEELE 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 264 RLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCL-VPGFRIGWVAGGSH--ARQIQRLQLMST 340
Cdd:cd00609  156 ELAELAKKHGILIISDEAYAELVYDGEPPPALALLDAYERVIVLRSFSKTFgLPGLRIGYLIAPPEelLERLKKLLPYTT 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 341 LSTSSPMQLALVDYLSTRryDAHLRRLRRQLAERKQQAWQTLLRHLPaeVKIHHNDSGYFLWLELPEQLDAGELSAKALE 420
Cdd:cd00609  236 SGPSTLSQAAAAAALDDG--EEHLEELRERYRRRRDALLEALKELGP--LVVVKPSGGFFLWLDLPEGDDEEFLERLLLE 311
                        330       340
                 ....*....|....*....|....*.
gi 446683342 421 HLISIAPGKMFSTSGAwtRFFRFNTA 446
Cdd:cd00609  312 AGVVVRPGSAFGEGGE--GFVRLSFA 335
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
145-466 1.21e-48

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 171.47  E-value: 1.21e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 145 PGNAELRYAIARRYAQ-QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGAlqALERLRLKALSIPTD 221
Cdd:COG0436   67 AGIPELREAIAAYYKRrYGVDLDPDEILVTNGAKEALALALLALLNPGDEVLVPDPGYpsYRA--AVRLAGGKPVPVPLD 144
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 222 VKEG--IDLMALEQALQEypvKACWLMTNS-QNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPL-PAKA 297
Cdd:COG0436  145 EENGflPDPEALEAAITP---RTKAIVLNSpNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVsILSL 221
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 298 WDRDDTVLHCSSFSKCL-VPGFRIGWVAGGSH-ARQIQRLQLMSTLSTSSPMQLALVDYLSTrrYDAHLRRLRRQLAERK 375
Cdd:COG0436  222 PGLKDRTIVINSFSKSYaMTGWRIGYAVGPPElIAALLKLQSNLTSCAPTPAQYAAAAALEG--PQDYVEEMRAEYRRRR 299
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 376 QQAWQTLLRhlpAEVKIHHNDSGYFLWLELPE-QLDAGELSAKAL-EHLISIAPGKMFSTSGAwtRFFRFNTAwHWGERE 453
Cdd:COG0436  300 DLLVEGLNE---IGLSVVKPEGAFYLFADVPElGLDSEEFAERLLeEAGVAVVPGSAFGPAGE--GYVRISYA-TSEERL 373
                        330
                 ....*....|...
gi 446683342 454 EQAVKQLGSLIRE 466
Cdd:COG0436  374 EEALERLARFLER 386
PRK15481 PRK15481
transcriptional regulatory protein PtsJ; Provisional
9-411 1.76e-36

transcriptional regulatory protein PtsJ; Provisional


Pssm-ID: 185378 [Multi-domain]  Cd Length: 431  Bit Score: 139.41  E-value: 1.76e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   9 EQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYV--APHPVCRSVATAAHVIRDea 86
Cdd:PRK15481  12 DSIRQLIQAGRLRPGDSLPPVRELASELGVNRNTVAAAYKRLVTAGLAQSQGRNGTVIrgSPSPVALEGGDPGTPLHD-- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  87 vdintyifemlqasrdtsvvpFASAFPDPRLfpLPQLNRSLAQVSKTATAMSVienlPPGNAELRyAIARRYAQQGITVs 166
Cdd:PRK15481  90 ---------------------LAGGNPDPQR--LPDLSRYFARLSRTPRLYGD----APVSPELH-AWAARWLRDDCPV- 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 167 PDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVkEGIDLMALEQALQEyPVKACWLM 246
Cdd:PRK15481 141 AFEIDLTSGAIDAIERLLCAHLLPGDSVAVEDPCFLSSINMLRYAGFSASPVSVDA-EGMQPEKLERALAQ-GARAVILT 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 247 TNSQNPLGFTLSAEKKARLVALLTHH-NVMLIEDDVYSELYFGR-EKPLPAKA--WdrddTVLHcsSFSKCLVPGFRIGW 322
Cdd:PRK15481 219 PRAHNPTGCSLSARRAAALRNLLARYpQVLVIIDDHFALLSSSPyHSVIPQTTqrW----ALIR--SVSKALGPDLRLAF 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 323 VAGGSHARQIQRLQLMS-TLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHlpaevKIHHNDS--GY 399
Cdd:PRK15481 293 VASDSATSARLRLRLNSgTQWVSHLLQDLVYACLTDPEYQARLAQARLFYAQRRQKLARALQQY-----GIAIPSPgdGL 367
                        410
                 ....*....|..
gi 446683342 400 FLWLELPEQLDA 411
Cdd:PRK15481 368 NLWLPLDTDSQA 379
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
146-442 4.17e-31

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 123.51  E-value: 4.17e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKE 224
Cdd:PRK06108  62 GIPELREALARYVSRLhGVATPPERIAVTSSGVQALMLAAQALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVPLDFGG 141
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 225 G---IDLMALEQALQEypvKACWLMTNS-QNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPA--KAW 298
Cdd:PRK06108 142 GgwtLDLDRLLAAITP---RTRALFINSpNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGGRAPSflDIA 218
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 299 DRDDTVLHCSSFSKC-LVPGFRIGW-VAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLS-----TRRYDAHLRRLRRQL 371
Cdd:PRK06108 219 EPDDRIIFVNSFSKNwAMTGWRLGWlVAPPALGQVLEKLIEYNTSCVAQFVQRAAVAALDegedfVAELVARLRRSRDHL 298
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446683342 372 AErkqqawqtLLRHLPAeVKIHHNDSGYFLWLELPEQLDAGELsAKAL--EHLISIAPGKMFSTSGAwtRFFR 442
Cdd:PRK06108 299 VD--------ALRALPG-VEVAKPDGAMYAFFRIPGVTDSLAL-AKRLvdEAGLGLAPGTAFGPGGE--GFLR 359
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
114-448 4.14e-28

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 114.32  E-value: 4.14e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  114 DPRLFPLPqlnrSLAQVSKTATAMSVIENLPP--GNAELRYAIARRY-AQQGITVSP-DEIVITAGALEALNLSLQAVTA 189
Cdd:pfam00155  10 EYLGDTLP----AVAKAEKDALAGGTRNLYGPtdGHPELREALAKFLgRSPVLKLDReAAVVFGSGAGANIEALIFLLAN 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  190 PGDWVVVENPCFYGALQALERLRLKALSIPTDVKEG--IDLMALEQALQEypvKACWLMTNS-QNPLGFTLSAEKKARLV 266
Cdd:pfam00155  86 PGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSNDfhLDFDALEAALKE---KPKVVLHTSpHNPTGTVATLEELEKLL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  267 ALLTHHNVMLIEDDVYSELYFGREKPLPAKAW-DRDDTVLHCSSFSKCL-VPGFRIGWVAGGSHARQIQRlQLMSTLSTS 344
Cdd:pfam00155 163 DLAKEHNILLLVDEAYAGFVFGSPDAVATRALlAEGPNLLVVGSFSKAFgLAGWRVGYILGNAAVISQLR-KLARPFYSS 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  345 SPMQLALVDYLSTR-RYDAHLRRLRRQLAERKQQawqtLLRHLPAEVKIH-HNDSGYFLWLELPEqLDAGELSAKAL-EH 421
Cdd:pfam00155 242 THLQAAAAAALSDPlLVASELEEMRQRIKERRDY----LRDGLQAAGLSVlPSQAGFFLLTGLDP-ETAKELAQVLLeEV 316
                         330       340
                  ....*....|....*....|....*..
gi 446683342  422 LISIAPGKMFSTSGawtrFFRFNTAWH 448
Cdd:pfam00155 317 GVYVTPGSSPGVPG----WLRITVAGG 339
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
145-324 2.52e-24

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 104.50  E-value: 2.52e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 145 PGNAELRYAIARRYA-QQGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALqaLERLRLKALSIPTD 221
Cdd:PRK06836  73 AGYPEVREAIAESLNrRFGTPLTADHIVMTCGAAGALNVALKAILNPGDEVIVFAPYFveYRFY--VDNHGGKLVVVPTD 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 222 VKE-GIDLMALEQALQEyPVKAcwLMTNS-QNPLGFTLSAEKKARLVALL------THHNVMLIEDDVYSEL-YFGREKP 292
Cdd:PRK06836 151 TDTfQPDLDALEAAITP-KTKA--VIINSpNNPTGVVYSEETLKALAALLeekskeYGRPIYLISDEPYREIvYDGAEVP 227
                        170       180       190
                 ....*....|....*....|....*....|...
gi 446683342 293 LPAKAWDRddTVLhCSSFSKCL-VPGFRIGWVA 324
Cdd:PRK06836 228 YIFKYYDN--SIV-VYSFSKSLsLPGERIGYIA 257
PRK07550 PRK07550
aminotransferase;
119-443 1.58e-20

aminotransferase;


Pssm-ID: 181026 [Multi-domain]  Cd Length: 386  Bit Score: 93.10  E-value: 1.58e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 119 PLPQLNRSLAQV--SKTATAMSVIEnlppGNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSLQAVTAPGDWVV 195
Cdd:PRK07550  43 PPPELLRALAEAaaDPAAHLYGPVE----GLPELREAYAAHYSRLyGAAISPEQVHITSGCNQAFWAAMVTLAGAGDEVI 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 196 VENPCFYGALQALERLRLKALSIPTDVKEGI--DLMALEQALQEyPVKACWLMTNSqNPLGFTLSAEKKARLVALLTHHN 273
Cdd:PRK07550 119 LPLPWYFNHKMWLDMLGIRPVYLPCDEGPGLlpDPAAAEALITP-RTRAIALVTPN-NPTGVVYPPELLHELYDLARRHG 196
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 274 VMLIEDDVYSELYFGREKP---LPAKAWdrDDTVLHCSSFSK--CLvPGFRIGWVAgGSHARQIQRLQLMSTLSTSSPM- 347
Cdd:PRK07550 197 IALILDETYRDFDSGGGAPhdlFADPDW--DDTLVHLYSFSKsyAL-TGHRVGAVV-ASPARIAEIEKFMDTVAICAPRi 272
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 348 -QLA-------LVDYLSTRRYDAHLRR--LRRQLAERKQqaWQTLlrhlpaevkihhnDSG-YFLWLELPEQLDAGELSA 416
Cdd:PRK07550 273 gQIAvawglpnLADWRAGNRAEIARRRdaFRAVFARLPG--WELL-------------ASGaYFAYVRHPFPDRPSREVA 337
                        330       340
                 ....*....|....*....|....*....
gi 446683342 417 KAL--EHLISIAPGKMFSTSGAwtRFFRF 443
Cdd:PRK07550 338 RRLakEAGILCLPGTMFGPGQE--GYLRL 364
PRK05764 PRK05764
aspartate aminotransferase; Provisional
145-376 4.18e-20

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 91.73  E-value: 4.18e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 145 PGNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGalqalERLRL---KALSI 218
Cdd:PRK05764  68 AGIPELREAIAAKLKRDnGLDYDPSQVIVTTGAKQALYNAFMALLDPGDEVIIPAPYWvsYP-----EMVKLaggVPVFV 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 219 PTDVKEG--IDLMALEQALQEyPVKacWLMTNS-QNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREK--PL 293
Cdd:PRK05764 143 PTGEENGfkLTVEQLEAAITP-KTK--ALILNSpSNPTGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEftSI 219
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 294 PAKAWD-RDDTVLhCSSFSKCL-VPGFRIGWVAGGSH-ARQIQRLQLMSTLSTSSPMQLALVDYLSTRryDAHLRRLRRQ 370
Cdd:PRK05764 220 ASLSPElRDRTIT-VNGFSKAYaMTGWRLGYAAGPKElIKAMSKLQSHSTSNPTSIAQYAAVAALNGP--QDEVEEMRQA 296

                 ....*.
gi 446683342 371 LAERKQ 376
Cdd:PRK05764 297 FEERRD 302
WHTH_GntR cd07377
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ...
2-67 5.95e-20

Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.


Pssm-ID: 153418 [Multi-domain]  Cd Length: 66  Bit Score: 83.27  E-value: 5.95e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446683342   2 KKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVA 67
Cdd:cd07377    1 PLYEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
4-89 1.37e-18

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 80.99  E-value: 1.37e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   4 YQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHPVCRSVATAAHVIR 83
Cdd:COG1725   12 YEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARELLEERREEFLE 91

                 ....*.
gi 446683342  84 DEAVDI 89
Cdd:COG1725   92 EALREL 97
PRK07777 PRK07777
putative succinyldiaminopimelate transaminase DapC;
91-401 1.44e-18

putative succinyldiaminopimelate transaminase DapC;


Pssm-ID: 236095 [Multi-domain]  Cd Length: 387  Bit Score: 87.40  E-value: 1.44e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  91 TYIF-EMLQASRDTSVVPFASAFPD---PRlfplpqlnrSLAQVSKTATAMSVIENLP-PGNAELRYAIA----RRYaqq 161
Cdd:PRK07777  11 TTIFaEMSALAVRTGAVNLGQGFPDedgPP---------EMLEAAQEAIAGGVNQYPPgPGIPELRAAIAaqrrRRY--- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 162 GITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALQALERLRLKALSI-PTDVKEGIDLMALEQALQE 237
Cdd:PRK07777  79 GLEYDPDtEVLVTVGATEAIAAAVLGLVEPGDEVLLIEPYYdsYAAVIAMAGAHRVPVPLvPDGRGFALDLDALRAAVTP 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 238 ypvKACWLMTNS-QNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKA----WDRDDTVlhcSSFSK 312
Cdd:PRK07777 159 ---RTRALIVNSpHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARHLPLATlpgmRERTVTI---SSAAK 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 313 CL-VPGFRIGWVAGGSH-ARQIQRLQLMSTLSTSSPMQLALVDYLSTRryDAHLRRLRRQLAERKQQAWQTLLRhlpAEV 390
Cdd:PRK07777 233 TFnVTGWKIGWACGPAPlIAAVRAAKQYLTYVGGAPFQPAVAHALDHE--DAWVAALRDSLQAKRDRLAAGLAE---AGF 307
                        330
                 ....*....|.
gi 446683342 391 KIHHNDSGYFL 401
Cdd:PRK07777 308 EVHDSAGTYFL 318
PRK07683 PRK07683
aminotransferase A; Validated
113-382 2.18e-18

aminotransferase A; Validated


Pssm-ID: 236075  Cd Length: 387  Bit Score: 86.70  E-value: 2.18e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 113 PDprlFPLPQLNRSLAQVSKTATAMSVIENlpPGNAELRYAIARRYAQQ-GITVSPD-EIVITAGALEALNLSLQAVTAP 190
Cdd:PRK07683  38 PD---FPTPSHVKEAAKRAITENYTSYTHN--AGLLELRKAACNFVKDKyDLHYSPEsEIIVTIGASEAIDIAFRTILEP 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 191 GDWVVVENPcFYGALQALERL-RLKALSIPTDvKEGIDLMAleQALQEY--PVKACWLMTNSQNPLGFTLSAEKKARLVA 267
Cdd:PRK07683 113 GTEVILPAP-IYPGYEPIIRLcGAKPVFIDTR-STGFRLTA--EALENAitEKTRCVVLPYPSNPTGVTLSKEELQDIAD 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 268 LLTHHNVMLIEDDVYSELYFGREKPLPAKAWD-RDDT-VLHCSSFSKCLVpGFRIGWVAGGSH-ARQIQRLQLMSTLSTS 344
Cdd:PRK07683 189 VLKDKNIFVLSDEIYSELVYEQPHTSIAHFPEmREKTiVINGLSKSHSMT-GWRIGFLFAPSYlAKHILKVHQYNVTCAS 267
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 446683342 345 SPMQLALVDYLSTRRYDAHLrrLRRQLAERKQQAWQTL 382
Cdd:PRK07683 268 SISQYAALEALTAGKDDAKM--MRHQYKKRRDYVYNRL 303
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
146-350 3.43e-18

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 86.26  E-value: 3.43e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVke 224
Cdd:PRK08960  70 GLPALREAIAGFYAQRyGVDVDPERILVTPGGSGALLLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGP-- 147
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 225 gidlmalEQALQEYP--VKACW-------LMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPlpa 295
Cdd:PRK08960 148 -------DSRYQLTPalVERHWnadtvgaLVASPANPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYGVDAA--- 217
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446683342 296 KAWDRDDTVLHCSSFSKCL-VPGFRIGW-VAGGSHARQIQRLQLMSTLSTSSPMQLA 350
Cdd:PRK08960 218 SVLEVDDDAFVLNSFSKYFgMTGWRLGWlVAPPAAVPELEKLAQNLYISASTPAQHA 274
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
145-324 7.09e-18

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 85.47  E-value: 7.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  145 PGNAELRYAIARRYAQQGITV-SPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALQALERLRLKALSIPTD 221
Cdd:TIGR01265  73 VGALAAREAVAEYLSSDLPGKlTADDVVLTSGCSQAIEICIEALANPGANILVPRPGFplYDTRAAFSGLEVRLYDLLPE 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  222 VKEGIDLMALEQALQEYPVkaCWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRD 301
Cdd:TIGR01265 153 KDWEIDLDGLESLADEKTV--AIVVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPMASFASI 230
                         170       180
                  ....*....|....*....|....
gi 446683342  302 DTVLHCSSFSK-CLVPGFRIGWVA 324
Cdd:TIGR01265 231 VPVLSLGGISKrWVVPGWRLGWII 254
PRK07682 PRK07682
aminotransferase;
125-435 8.30e-18

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 84.79  E-value: 8.30e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 125 RSLAQ--VSKTATAmsvienlppGNAELRYAIARRYAQQ-GITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPC 200
Cdd:PRK07682  44 RSLEQgyTSYTANA---------GLLELRQEIAKYLKKRfAVSYDPNdEIIVTVGASQALDVAMRAIINPGDEVLIVEPS 114
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 201 F--YGALQALErlRLKALSIPTDVKEGIDLMA--LEQALQEyPVKACWLMTNSqNPLGFTLSAEKKARLVALLTHHNVML 276
Cdd:PRK07682 115 FvsYAPLVTLA--GGVPVPVATTLENEFKVQPaqIEAAITA-KTKAILLCSPN-NPTGAVLNKSELEEIAVIVEKHDLIV 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 277 IEDDVYSEL-YFGREKPLPAKAWDRDDTVLhCSSFSKCL-VPGFRIGWVAGGSHARQ----IQRLQLMSTLSTSspmQLA 350
Cdd:PRK07682 191 LSDEIYAELtYDEAYTSFASIKGMRERTIL-ISGFSKGFaMTGWRLGFIAAPVYFSEamlkIHQYSMMCAPTMA---QFA 266
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 351 LVDYLSTRRYDAHlrRLRRQLAERKQQAWQTLlrhlpAEVKI--HHNDSGYFLWLELPEQLDAGELSAKAL--EHLISIA 426
Cdd:PRK07682 267 ALEALRAGNDDVI--RMRDSYRKRRNFFVTSF-----NEIGLtcHVPGGAFYAFPSISSTGLSSEEFAEQLllEEKVAVV 339

                 ....*....
gi 446683342 427 PGKMFSTSG 435
Cdd:PRK07682 340 PGSVFGESG 348
PRK07568 PRK07568
pyridoxal phosphate-dependent aminotransferase;
146-324 9.24e-18

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181036  Cd Length: 397  Bit Score: 84.90  E-value: 9.24e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQQGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPcFYGALQA-LERLRLKALSIPTDVKE 224
Cdd:PRK07568  67 GIPELREAFAKYYKKWGIDVEPDEILITNGGSEAILFAMMAICDPGDEILVPEP-FYANYNGfATSAGVKIVPVTTKIEE 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 225 GIDLMALEqALQEY--PVKACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAW-DRD 301
Cdd:PRK07568 146 GFHLPSKE-EIEKLitPKTKAILISNPGNPTGVVYTKEELEMLAEIAKKHDLFLISDEVYREFVYDGLKYTSALSLeGLE 224
                        170       180
                 ....*....|....*....|....*..
gi 446683342 302 DTVLHCSSFSK----ClvpGFRIGWVA 324
Cdd:PRK07568 225 DRVIIIDSVSKrysaC---GARIGCLI 248
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
146-323 2.32e-17

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 83.68  E-value: 2.32e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  146 GNAELRYAIARRYAQQGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENP--CFYGALQALERLRLKALSIPTDVK 223
Cdd:TIGR01264  74 GALSAREAIASYYHNPDGPIEADDVVLCSGCSHAIEMCIAALANAGQNILVPRPgfPLYETLAESMGIEVKLYNLLPDKS 153
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  224 EGIDLMALEQALQEYpvKACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDT 303
Cdd:TIGR01264 154 WEIDLKQLESLIDEK--TAALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFSGATFEPLASLSSTVP 231
                         170       180
                  ....*....|....*....|.
gi 446683342  304 VLHCSSFSK-CLVPGFRIGWV 323
Cdd:TIGR01264 232 ILSCGGLAKrWLVPGWRLGWI 252
PRK08912 PRK08912
aminotransferase;
88-373 2.82e-17

aminotransferase;


Pssm-ID: 181580  Cd Length: 387  Bit Score: 83.49  E-value: 2.82e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  88 DINTYIFE-MLQASRDTSVVPFASAFPDPrlfPLPQLNRSlaqvsktATAMSVIE---NLPP--GNAELRYAIARRYAQ- 160
Cdd:PRK08912  10 DLPTTIFEvMSQLAREHGAINLGQGFPDD---PGPEDVRR-------AAADALLDgsnQYPPmmGLPELRQAVAAHYARf 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 161 QGITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPcFYGALQALERL-----RLKALSIPtdvKEGIDLMALEQA 234
Cdd:PRK08912  80 QGLDLDPEtEVMVTSGATEALAAALLALVEPGDEVVLFQP-LYDAYLPLIRRaggvpRLVRLEPP---HWRLPRAALAAA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 235 LQEyPVKACwLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFG--REKPLPAKAWDRDDTVLHCS---S 309
Cdd:PRK08912 156 FSP-RTKAV-LLNNPLNPAGKVFPREELALLAEFCQRHDAVAICDEVWEHVVFDgrRHIPLMTLPGMRERTVKIGSagkI 233
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446683342 310 FSkclVPGFRIGWV-AGGSHARQIQRLQLMSTLSTSSPMQLALV-------DYLSTRRydAHLRRLRRQLAE 373
Cdd:PRK08912 234 FS---LTGWKVGFVcAAPPLLRVLAKAHQFLTFTTPPNLQAAVAyglgkpdDYFEGMR--ADLARSRDRLAA 300
PLN00175 PLN00175
aminotransferase family protein; Provisional
146-376 1.11e-16

aminotransferase family protein; Provisional


Pssm-ID: 215089 [Multi-domain]  Cd Length: 413  Bit Score: 81.83  E-value: 1.11e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQQ-GITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPcFYGALQAlerlrlkALSIPTDVK 223
Cdd:PLN00175  92 GVPELNSAIAERFKKDtGLVVDPEkEVTVTSGCTEAIAATILGLINPGDEVILFAP-FYDSYEA-------TLSMAGAKI 163
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 224 EGIDLMALEQALQEYPVKACW-------LMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREK----P 292
Cdd:PLN00175 164 KTVTLRPPDFAVPEDELKAAFtsktraiLINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFEGDHismaS 243
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 293 LPAkAWDRDDTVlhcSSFSKCL-VPGFRIGWVAGGSH-ARQIQRLQLMSTLSTSSPMQLALVDYLstRRYDAHLRRLRRQ 370
Cdd:PLN00175 244 LPG-MYERTVTM---NSLGKTFsLTGWKIGWAIAPPHlTWGVRQAHSFLTFATATPMQWAAVAAL--RAPESYYEELKRD 317

                 ....*.
gi 446683342 371 LAERKQ 376
Cdd:PLN00175 318 YSAKKD 323
PRK09082 PRK09082
methionine aminotransferase; Validated
91-367 1.23e-16

methionine aminotransferase; Validated


Pssm-ID: 181642 [Multi-domain]  Cd Length: 386  Bit Score: 81.50  E-value: 1.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  91 TYIF-EMLQASRDTSVVPFASAFPDprlFPLPQlnrslAQVSKTATAMSVIEN-LPP--GNAELRYAIARRYAQ-QGITV 165
Cdd:PRK09082  17 TTIFtVMSALAAEHGAINLSQGFPD---FDGPP-----YLVEALAYAMAAGHNqYPPmtGVAALREAIAAKTARlYGRQY 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 166 SPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALE----RLRLKALSIPTdvkEGIDLMALEQALQEypv 240
Cdd:PRK09082  89 DADsEITVTAGATEALFAAILALVRPGDEVIVFDPSYDSYAPAIElaggRAVRVALQPPD---FRVDWQRFAAAISP--- 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 241 KACWLMTNS-QNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWD----RDDTVlhcSSFSKCL- 314
Cdd:PRK09082 163 RTRLIILNTpHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGHASVLRHPelreRAFVV---SSFGKTYh 239
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446683342 315 VPGFRIGWVAG----GSHARQIQrlQLMsTLSTSSPMQLALVDYLstRRYDAHLRRL 367
Cdd:PRK09082 240 VTGWKVGYCVApaalSAEFRKVH--QYN-TFTVNTPAQLALADYL--RAEPEHYLEL 291
PRK08361 PRK08361
aspartate aminotransferase; Provisional
146-439 2.36e-16

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 80.69  E-value: 2.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQ-QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPtdVKE 224
Cdd:PRK08361  71 GIPELREAIAEYYKKfYGVDVDVDNVIVTAGAYEATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIP--LRE 148
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 225 GIDLMALEQALQEYPVKACWL--MTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDD 302
Cdd:PRK08361 149 ENEFQPDPDELLELITKRTRMivINYPNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHYPMIKYAPDN 228
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 303 TVLhCSSFSKCL-VPGFRIGWVAGGSHA-RQIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQ 380
Cdd:PRK08361 229 TIL-ANSFSKTFaMTGWRLGFVIAPEQViKDMIKLHAYIIGNVASFVQIAGIEALRSKESWKAVEEMRKEYNERRKLVLK 307
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446683342 381 TlLRHLPaEVKIHHNDSGYFLWLELPE-QLDAGELSAKALEHL-ISIAPGKMFSTSG-AWTR 439
Cdd:PRK08361 308 R-LKEMP-HIKVFEPKGAFYVFANIDEtGMSSEDFAEWLLEKArVVVIPGTAFGKAGeGYIR 367
PRK06207 PRK06207
pyridoxal phosphate-dependent aminotransferase;
146-393 2.98e-16

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235742  Cd Length: 405  Bit Score: 80.58  E-value: 2.98e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQ-QGITVSP-DEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERL-------RLKAL 216
Cdd:PRK06207  79 GDADIRELLAARLAAfTGAPVDAaDELIITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFegemvpvQLDYL 158
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 217 SipTDVKEGIDLMALEQALQEyPVKAcWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSEL-YFGRE-KPLP 294
Cdd:PRK06207 159 S--ADKRAGLDLDQLEEAFKA-GVRV-FLFSNPNNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLlYDGTSyTHLR 234
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 295 AKAWDRDD--TVLHCS---SFSkclvpGFRIGwVAGGSHA--RQIQRLQLMSTLSTSSPMQLALVDYLS------TRRYD 361
Cdd:PRK06207 235 ALPIDPENviTIMGPSkteSLS-----GYRLG-VAFGSPAiiDRMEKLQAIVSLRAAGYSQAVLRTWFSepdgwmKDRIA 308
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 446683342 362 AH-------LRRLR--RQLAERKQQAWQTLLRHLPA-EVKIH 393
Cdd:PRK06207 309 RHqairddlLRVLRgvEGVFVRAPQAGSYLFPRLPRlAVSLH 350
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
144-435 2.54e-15

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 77.45  E-value: 2.54e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 144 PPGNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDV 222
Cdd:PRK06348  65 SGGDVELIEEIIKYYSKNyDLSFKRNEIMATVGACHGMYLALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYE 144
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 223 KEG--IDLMALEqALQEYPVKAcwLMTNS-QNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGRE-KPLPAKAW 298
Cdd:PRK06348 145 EDGfqINVKKLE-ALITSKTKA--IILNSpNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFYEDfVPMATLAG 221
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 299 DRDDTVLhCSSFSKCL-VPGFRIGWVAGGSHARQ-IQRLQLMSTLSTSSPMQLALVdylstrrydaHLRRLRRQLAERKQ 376
Cdd:PRK06348 222 MPERTIT-FGSFSKDFaMTGWRIGYVIAPDYIIEtAKIINEGICFSAPTISQRAAI----------YALKHRDTIVPLIK 290
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446683342 377 QAWQTLLRHLPAEVK------IHHNDSGYFLWLELPEQ-LDAGELSAKALE--HLISIaPGKMFSTSG 435
Cdd:PRK06348 291 EEFQKRLEYAYKRIEsipnlsLHPPKGSIYAFINIKKTgLSSVEFCEKLLKeaHVLVI-PGKAFGESG 357
PRK09148 PRK09148
LL-diaminopimelate aminotransferase;
145-435 3.97e-15

LL-diaminopimelate aminotransferase;


Pssm-ID: 181674 [Multi-domain]  Cd Length: 405  Bit Score: 77.03  E-value: 3.97e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 145 PGnaeLRYAIARRYAQQ-GITVSPD-EIVITAGALEAL-NLSlQAVTAPGDWVVVENPCF----YGALQALERLRlkalS 217
Cdd:PRK09148  71 PG---LRRAQAAYYARRfGVKLNPDtQVVATLGSKEGFaNMA-QAITAPGDVILCPNPSYpihaFGFIMAGGVIR----S 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 218 IPTDVKEGIdLMALEQALQEYPVKACWLMTN-SQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKP---- 292
Cdd:PRK09148 143 VPAEPDEEF-FPALERAVRHSIPKPIALIVNyPSNPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYFDGNPPpsvl 221
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 293 -LP-AKawdrdDTVLHCSSFSKCL-VPGFRIGWVAGgsHARQIQRL-QLMSTLSTS--SPMQLALV-------DYLSTRR 359
Cdd:PRK09148 222 qVPgAK-----DVTVEFTSMSKTFsMAGWRMGFAVG--NERLIAALtRVKSYLDYGafTPIQVAATaalngpqDCIAEMR 294
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 360 ydAHLRRLRRQLAERKQQA-WQtllrhLPAEvkihhnDSGYFLWLELPEQL-DAG--ELSAKALEHL-ISIAPGKMFSTS 434
Cdd:PRK09148 295 --ELYKKRRDVLVESFGRAgWD-----IPPP------AASMFAWAPIPEAFrHLGslEFSKLLVEKAdVAVAPGVGFGEH 361

                 .
gi 446683342 435 G 435
Cdd:PRK09148 362 G 362
PRK07309 PRK07309
pyridoxal phosphate-dependent aminotransferase;
135-362 4.95e-15

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235985  Cd Length: 391  Bit Score: 76.69  E-value: 4.95e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 135 TAMSvienlppGNAELRYAIARRYAQQ-GITVSP-DEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLR 212
Cdd:PRK07309  64 TGMA-------GLLELRQAAADFVKEKyNLDYAPeNEILVTIGATEALSASLTAILEPGDKVLLPAPAYPGYEPIVNLVG 136
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 213 LKALSIPTDVKEGIdLMA--LEQALQEYP--VKACWLMTNSqNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFG 288
Cdd:PRK07309 137 AEIVEIDTTENDFV-LTPemLEKAILEQGdkLKAVILNYPA-NPTGVTYSREQIKALADVLKKYDIFVISDEVYSELTYT 214
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446683342 289 REKPLPAKAWDRDDTVLhCSSFSKC-LVPGFRIGWVAGGSH--ARQIQRLQLMSTLSTSSpMQLALVDYLSTRRYDA 362
Cdd:PRK07309 215 GEPHVSIAEYLPDQTIL-INGLSKShAMTGWRIGLIFAPAEftAQLIKSHQYLVTAATTM-AQFAAVEALTNGKDDA 289
MngR COG2188
DNA-binding transcriptional regulator, GntR family [Transcription];
3-106 5.14e-15

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441791 [Multi-domain]  Cd Length: 238  Bit Score: 74.51  E-value: 5.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   3 KYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHPVCRSV------- 75
Cdd:COG2188    6 LYLQIADALRERIESGELPPGDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERRQGRGTFVAEPKIEYPLsrltsft 85
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 446683342  76 --------ATAAHVIRDEAVDINTYIFEMLQASRDTSVV 106
Cdd:COG2188   86 eelrargrEPSTRVLSAERVPADEEVAEALGLPPGAPVL 124
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
117-421 7.14e-15

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 75.55  E-value: 7.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 117 LFPLPQLNRSLAQvsktatAMSVIENLP-PGNAELRYAIARRYAqqgitVSPDEIVITAGALEALNLSLQAVTAPGDWVV 195
Cdd:COG0079   25 YGPPPKVLEAIAA------ALDALNRYPdPDATALREALAEYYG-----VPPEQVLVGNGSDELIQLLARAFLGPGDEVL 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 196 VENPCF--YGAlqALERLRLKALSIPTDVKEGIDLMALEQALQEyPVKACWLmTNSQNPLGFTLSAEKKARLVALLTHHn 273
Cdd:COG0079   94 VPEPTFseYPI--AARAAGAEVVEVPLDEDFSLDLDALLAAITE-RTDLVFL-CNPNNPTGTLLPREELEALLEALPAD- 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 274 VMLIEDDVYSElyFGREKPLPAKAWDRDDTVLHCSSFSKCL-VPGFRIGWVAGgsHARQIQRLQLMSTL-STSSPMQLAL 351
Cdd:COG0079  169 GLVVVDEAYAE--FVPEEDSALPLLARYPNLVVLRTFSKAYgLAGLRLGYAIA--SPELIAALRRVRGPwNVNSLAQAAA 244
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446683342 352 VDYLstrRYDAHLRRLRRQLAERKQQAWQTLlrhlpAEVKIHHNDS-GYFLWLELPEqlDAGELSAKALEH 421
Cdd:COG0079  245 LAAL---EDRAYLEETRARLRAERERLAAAL-----RALGLTVYPSqANFVLVRVPE--DAAELFEALLER 305
PRK06107 PRK06107
aspartate transaminase;
146-356 3.72e-14

aspartate transaminase;


Pssm-ID: 180403  Cd Length: 402  Bit Score: 74.00  E-value: 3.72e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKE 224
Cdd:PRK06107  71 GTPALRKAIIAKLERRnGLHYADNEITVGGGAKQAIFLALMATLEAGDEVIIPAPYWVSYPDMVLANDGTPVIVACPEEQ 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 225 GIDLM--ALEQALQEypvKACWLMTNS-QNPLGFTLSAEKKARLVA-LLTHHNVMLIEDDVYSELYFGREkPLP---AKA 297
Cdd:PRK06107 151 GFKLTpeALEAAITP---RTRWLILNApSNPTGAVYSRAELRALADvLLRHPHVLVLTDDIYDHIRFDDE-PTPhllAAA 226
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446683342 298 WDRDDTVLHCSSFSKCL-VPGFRIGWVAGGSHARQ-IQRLQLMSTLSTSSPMQLALVDYLS 356
Cdd:PRK06107 227 PELRDRVLVTNGVSKTYaMTGWRIGYAAGPADLIAaINKLQSQSSSCPSSISQAAAAAALN 287
his_ut_repres TIGR02018
histidine utilization repressor, proteobacterial; This model represents a proteobacterial ...
3-113 5.66e-14

histidine utilization repressor, proteobacterial; This model represents a proteobacterial histidine utilization repressor. It is usually found clustered with the enzymes HutUHIG so that it can regulate its own expression as well. A number of species have several paralogs and may fine-tune the regulation according to levels of degradation intermediates such as urocanate. This family belongs to the larger GntR family of transcriptional regulators. [Energy metabolism, Amino acids and amines, Regulatory functions, DNA interactions]


Pssm-ID: 188194 [Multi-domain]  Cd Length: 230  Bit Score: 71.19  E-value: 5.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342    3 KYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPhPVCRSVATAAHVI 82
Cdd:TIGR02018   2 LYQRIKQDILERIRSGEWPPGHRIPSEHELVAQYGCSRMTVNRALRELTDAGLLERRQGVGTFVAE-PKAQSALLEIRNI 80
                          90       100       110
                  ....*....|....*....|....*....|....
gi 446683342   83 RDEAVDI-NTYIFEML--QASRDTSVVPFASAFP 113
Cdd:TIGR02018  81 ADEIVARgHRYRYELLelETRRATAEDAAALALP 114
PLN02607 PLN02607
1-aminocyclopropane-1-carboxylate synthase
167-428 1.73e-13

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 215327 [Multi-domain]  Cd Length: 447  Bit Score: 72.23  E-value: 1.73e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 167 PDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALE-RLRLKALSIPTDVKEG--IDLMALEQALQE-----Y 238
Cdd:PLN02607 120 PDRIVLTAGATAANELLTFILADPGDALLVPTPYYPGFDRDLRwRTGVKIVPIHCDSSNNfqVTPQALEAAYQEaeaanI 199
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 239 PVKACwLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGRE------KPLPAKAWDRDDTVLH-CSSFS 311
Cdd:PLN02607 200 RVRGV-LITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSGSVFSASefvsvaEIVEARGYKGVAERVHiVYSLS 278
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 312 KCL-VPGFRIGWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRRY-DAHLRRLRRQLAERKQQAWQTLLRhlpAE 389
Cdd:PLN02607 279 KDLgLPGFRVGTIYSYNDKVVTTARRMSSFTLVSSQTQHLLASMLSDEEFtENYIRTNRERLRKRYEMIVQGLRR---AG 355
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 446683342 390 VKIHHNDSGYFLWLELPEQLD----AGELS--AKALEHL-ISIAPG 428
Cdd:PLN02607 356 IECLKGNAGLFCWMNLSPLLEtptrEGELAlwDSILREVkLNISPG 401
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
7-66 1.94e-13

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 64.90  E-value: 1.94e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342     7 LAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYV 66
Cdd:smart00345   1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
PRK08363 PRK08363
alanine aminotransferase; Validated
146-375 3.01e-13

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 70.99  E-value: 3.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARR-YAQQGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPC---------FYGAlqalerlrlKA 215
Cdd:PRK08363  71 GLPELREAIVKReKRKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILIPGPSyppytglvkFYGG---------VP 141
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 216 LSIPTDVKEGI--DLMALEQALQEYPVKACwlMTNSQNPLGfTLSAEKKAR-LVALLTHHNVMLIEDDVYSELYFGREKP 292
Cdd:PRK08363 142 VEYRTIEEEGWqpDIDDIRKKITEKTKAIA--VINPNNPTG-ALYEKKTLKeILDIAGEHDLPVISDEIYDLMTYEGKHV 218
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 293 LPAKAwDRDDTVLHCSSFSKC-LVPGFRIGWVAGGSHARQIQRLQ------LMSTLSTSSPMQLALVDYLstRRYDAHLR 365
Cdd:PRK08363 219 SPGSL-TKDVPVIVMNGLSKVyFATGWRLGYIYFVDPEGKLAEVReaidklARIRLCPNTPAQFAAIAGL--TGPMDYLE 295
                        250
                 ....*....|
gi 446683342 366 RLRRQLAERK 375
Cdd:PRK08363 296 EYMKKLKERR 305
GntR pfam00392
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ...
3-66 1.44e-12

Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.


Pssm-ID: 306822 [Multi-domain]  Cd Length: 64  Bit Score: 62.63  E-value: 1.44e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446683342    3 KYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYV 66
Cdd:pfam00392   1 LYEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
PRK07337 PRK07337
pyridoxal phosphate-dependent aminotransferase;
144-322 4.82e-12

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180937  Cd Length: 388  Bit Score: 67.39  E-value: 4.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 144 PPGNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPC------FYGALQALERLrlkal 216
Cdd:PRK07337  66 ALGLAPLREAIAAWYARRfGLDVAPERIVVTAGASAALLLACLALVERGDEVLMPDPSypcnrhFVAAAEGRPVL----- 140
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 217 sIPTDVKEGIDLMALEqalqeypVKACW-------LMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFgr 289
Cdd:PRK07337 141 -VPSGPAERFQLTAAD-------VEAAWgertrgvLLASPSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSY-- 210
                        170       180       190
                 ....*....|....*....|....*....|....
gi 446683342 290 EKPlPAKAWDRDDTVLHCSSFSKCL-VPGFRIGW 322
Cdd:PRK07337 211 DAA-PVSALSLGDDVITINSFSKYFnMTGWRLGW 243
PRK08068 PRK08068
transaminase; Reviewed
146-435 6.77e-12

transaminase; Reviewed


Pssm-ID: 181219  Cd Length: 389  Bit Score: 66.87  E-value: 6.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQQ-GITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPCF--Y--GALQA---LERLRLKA- 215
Cdd:PRK08068  71 GYPFLKEAAADFYKREyGVTLDPEtEVAILFGGKAGLVELPQCLMNPGDTILVPDPGYpdYlsGVALAraqFETMPLIAe 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 216 -------LSIPTDVKEGIDLMALEqalqeYPvkacwlmtnsQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFG 288
Cdd:PRK08068 151 nnflpdyTKIPEEVAEKAKLMYLN-----YP----------NNPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGFD 215
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 289 REKPLP------AKawdrdDTVLHCSSFSKCL-VPGFRIGWVAGgsHARQIQRLQLMST---LSTSSPMQLALVDYLSTR 358
Cdd:PRK08068 216 GQKPVSflqtpgAK-----DVGIELYTLSKTFnMAGWRVAFAVG--NESVIEAINLLQDhlfVSLFGAIQDAAIEALLSD 288
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446683342 359 ryDAHLRRLrRQLAERKQQAWQTLLRHLPAEVKIhhnDSG-YFLWLELPEQLDAGELSAKALEHL-ISIAPGKMFSTSG 435
Cdd:PRK08068 289 --QSCVAEL-VARYESRRNAFISACREIGWEVDA---PKGsFFAWMPVPKGYTSEQFADLLLEKAhVAVAPGNGFGEHG 361
PLN00145 PLN00145
tyrosine/nicotianamine aminotransferase; Provisional
146-324 1.04e-11

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 215074 [Multi-domain]  Cd Length: 430  Bit Score: 66.72  E-value: 1.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQQ-GITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENP--CFYGALQALERLRLKALSIPTDV 222
Cdd:PLN00145  95 GLLPARRAIAEYLSRDlPYELSTDDIYLTAGCAQAIEIIMSVLAQPGANILLPRPgyPLYEARAVFSGLEVRHFDLLPER 174
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 223 KEGIDLMALEQALQEYPVKAcwLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDD 302
Cdd:PLN00145 175 GWEVDLEGVEALADENTVAM--VIINPNNPCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTFGSKPFVPMGVFGEVA 252
                        170       180
                 ....*....|....*....|...
gi 446683342 303 TVLHCSSFSK-CLVPGFRIGWVA 324
Cdd:PLN00145 253 PVLTLGSISKrWVVPGWRLGWIA 275
FadR COG2186
DNA-binding transcriptional regulator, FadR family [Transcription];
2-99 2.25e-11

DNA-binding transcriptional regulator, FadR family [Transcription];


Pssm-ID: 441789 [Multi-domain]  Cd Length: 232  Bit Score: 63.41  E-value: 2.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   2 KKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPhpvcRSVATAAHV 81
Cdd:COG2186    7 SLAEQVAEQLRELILSGELKPGDRLPSERELAEQLGVSRTTVREALRALEALGLVEVRQGGGTFVRE----PSPWALLDP 82
                         90
                 ....*....|....*...
gi 446683342  82 IRDEAVDINTYIFEMLQA 99
Cdd:COG2186   83 LALLLALDDASLRDLLEA 100
PTZ00433 PTZ00433
tyrosine aminotransferase; Provisional
89-356 2.73e-11

tyrosine aminotransferase; Provisional


Pssm-ID: 185613  Cd Length: 412  Bit Score: 65.19  E-value: 2.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342  89 INTYIFEMLQASRDTSVVPFASAFP--DPRLFPLPQLNRSLAQVSKTatamSVIENLPP--GNAELRYAIA----RRYAQ 160
Cdd:PTZ00433  19 LRTVTDNAKPSPSPKSIIKLSVGDPtlDGNLLTPAIQTKALVEAVDS----QECNGYPPtvGSPEAREAVAtywrNSFVH 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 161 ---QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALQALERLRLKALSIPTDVKEGIDLMALeQAL 235
Cdd:PTZ00433  95 kesLKSTIKKDNVVLCSGVSHAILMALTALCDEGDNILVPAPGFphYETVCKAYGIEMRFYNCRPEKDWEADLDEI-RRL 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 236 QEYPVKAcWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCL- 314
Cdd:PTZ00433 174 VDDRTKA-LIMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNGATFTSVADFDTTVPRVILGGTAKNLv 252
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 446683342 315 VPGFRIGWV-------AGGSHARQIQRLQlMSTLSTSSPMQLALVDYLS 356
Cdd:PTZ00433 253 VPGWRLGWLllvdphgNGGDFLDGMKRLG-MLVCGPCSVVQAALGEALL 300
PLN02376 PLN02376
1-aminocyclopropane-1-carboxylate synthase
146-439 2.83e-11

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178004 [Multi-domain]  Cd Length: 496  Bit Score: 65.49  E-value: 2.83e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRY--AQQG-ITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPcFYGALQALERLR--LKALSIPT 220
Cdd:PLN02376  95 GLKKFRQAIAHFMgkARGGkVTFDPERVVMSGGATGANETIMFCLADPGDVFLIPSP-YYAAFDRDLRWRtgVEIIPVPC 173
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 221 DVKEGIDLM------ALEQALQEYPVKACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYF--GREKP 292
Cdd:PLN02376 174 SSSDNFKLTvdaadwAYKKAQESNKKVKGLILTNPSNPLGTMLDKDTLTNLVRFVTRKNIHLVVDEIYAATVFagGDFVS 253
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 293 LPAKAWDRD------DTVLHCSSFSKCL-VPGFRIGWV-----AGGSHARQIQRLQLMstlstSSPMQLALVDYLSTRRY 360
Cdd:PLN02376 254 VAEVVNDVDisevnvDLIHIVYSLSKDMgLPGFRVGIVysfndSVVSCARKMSSFGLV-----SSQTQLMLASMLSDDQF 328
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 361 -DAHLRRLRRQLAERkQQAWQTLLRHlpAEVKIHHNDSGYFLWLELPEQL-DAGELSAK-ALEHLI------SIAPGKMF 431
Cdd:PLN02376 329 vDNFLMESSRRLGIR-HKVFTTGIKK--ADIACLTSNAGLFAWMDLRHLLrDRNSFESEiELWHIIidkvklNVSPGSSF 405

                 ....*....
gi 446683342 432 S-TSGAWTR 439
Cdd:PLN02376 406 RcTEPGWFR 414
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
144-369 5.71e-11

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 64.00  E-value: 5.71e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 144 PPGNAELRYAIArryaqQGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENP-----CFYGALQALERLRLKALS- 217
Cdd:PRK06225  65 PEGFPELRELIL-----KDLGLDDDEALITAGATESLYLVMRAFLSPGDNAVTPDPgyliiDNFASRFGAEVIEVPIYSe 139
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 218 ------IPTDVKEGIDLMAleqalqeypvkACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSElyFGREK 291
Cdd:PRK06225 140 ecnyklTPELVKENMDENT-----------RLIYLIDPLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRD--FAREH 206
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446683342 292 PLPAKAwDRDDTVLhCSSFSK-CLVPGFRIGWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLSTRryDAHLRRLRR 369
Cdd:PRK06225 207 TLAAEY-APEHTVT-SYSFSKiFGMAGLRIGAVVATPDLIEVVKSIVINDLGTNVIAQEAAIAGLKVK--DEWIDRIRR 281
PLN02656 PLN02656
tyrosine transaminase
165-322 9.10e-11

tyrosine transaminase


Pssm-ID: 178262 [Multi-domain]  Cd Length: 409  Bit Score: 63.40  E-value: 9.10e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 165 VSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALQALERLRLKALSIPTDVKEGIDLMALEQALQEYPVka 242
Cdd:PLN02656  94 LSLDDVFITSGCTQAIDVALSMLARPGANILLPRPGFpiYELCAAFRHLEVRYVDLLPEKGWEVDLDAVEALADQNTV-- 171
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 243 CWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSK-CLVPGFRIG 321
Cdd:PLN02656 172 ALVIINPGNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGSNPFVPMGVFGSIVPVLTLGSLSKrWIVPGWRLG 251

                 .
gi 446683342 322 W 322
Cdd:PLN02656 252 W 252
PRK07324 PRK07324
transaminase; Validated
146-325 3.27e-10

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 61.49  E-value: 3.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQqgitVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF---------YGALQALERLRLKAL 216
Cdd:PRK07324  63 GSPEFKEAVASLYQN----VKPENILQTNGATGANFLVLYALVEPGDHVISVYPTYqqlydipesLGAEVDYWQLKEENG 138
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 217 SIPtdvkegiDLMALEQALQEYPVKACwlMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYseLYFGREKPLPAK 296
Cdd:PRK07324 139 WLP-------DLDELRRLVRPNTKLIC--INNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVY--RPLDEDGSTPSI 207
                        170       180       190
                 ....*....|....*....|....*....|..
gi 446683342 297 A--WDRDDTVlhcSSFSKCL-VPGFRIGWVAG 325
Cdd:PRK07324 208 AdlYEKGIST---NSMSKTYsLPGIRVGWIAA 236
PRK12414 PRK12414
putative aminotransferase; Provisional
145-356 1.01e-09

putative aminotransferase; Provisional


Pssm-ID: 183514  Cd Length: 384  Bit Score: 60.19  E-value: 1.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 145 PGNAELRYAIARRYAQ-QGITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALqalerLRLKAlSIPT 220
Cdd:PRK12414  66 AGIAALREALAEKTERlYGARYDPAsEVTVIASASEGLYAAISALVHPGDEVIYFEPSFdsYAPI-----VRLQG-ATPV 139
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 221 DVKEGIDLMAL---EQALQEYPVKACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYF-GREKPLPAK 296
Cdd:PRK12414 140 AIKLSPEDFRVnwdEVAAAITPRTRMIIVNTPHNPSATVFSAADLARLAQLTRNTDIVILSDEVYEHVVFdGARHHSMAR 219
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446683342 297 AWDRDDTVLHCSSFSKCL-VPGFRIGW-VAGGSHARQIQRLQLMSTLSTSSPMQLALVDYLS 356
Cdd:PRK12414 220 HRELAERSVIVSSFGKSYhVTGWRVGYcLAPAELMDEIRKVHQFMVFSADTPMQHAFAEALA 281
PLN02450 PLN02450
1-aminocyclopropane-1-carboxylate synthase
163-405 3.62e-09

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178069 [Multi-domain]  Cd Length: 468  Bit Score: 58.61  E-value: 3.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 163 ITVSPDEIVITAGALEAlNLSLQAVTA-PGDWVVVENPCFYGALQALeRLRLKALSIPTDVKEG----IDLMALEQALQE 237
Cdd:PLN02450 107 VTFDPNKLVLTAGATSA-NETLMFCLAePGDAFLLPTPYYPGFDRDL-KWRTGVEIVPIHCSSSngfqITESALEEAYQQ 184
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 238 -----YPVKACwLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGRE------------KPLPAKAWDR 300
Cdd:PLN02450 185 aqklnLKVKGV-LITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFDSPgfvsvmevlkdrKLENTDVSNR 263
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 301 DDTVLhcsSFSKCL-VPGFRIGWVAgGSHARQIQRLQLMSTLS-TSSPMQLALVDYLSTRRYDAH-LRRLRRQLAERKQQ 377
Cdd:PLN02450 264 VHIVY---SLSKDLgLPGFRVGAIY-SNDEMVVSAATKMSSFGlVSSQTQYLLSALLSDKKFTKNyLEENQKRLKQRQKK 339
                        250       260
                 ....*....|....*....|....*....
gi 446683342 378 awqtLLRHL-PAEVKIHHNDSGYFLWLEL 405
Cdd:PLN02450 340 ----LVSGLeAAGIKCLKSNAGLFCWVDM 364
PRK07681 PRK07681
LL-diaminopimelate aminotransferase;
146-435 3.91e-09

LL-diaminopimelate aminotransferase;


Pssm-ID: 181081  Cd Length: 399  Bit Score: 58.28  E-value: 3.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRY-AQQGITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALQALErlrlKALSIPTD 221
Cdd:PRK07681  70 GIQEFHEAVTEYYnNTHNVILNADkEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYtaYETGIQMA----GATSYYMP 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 222 VKEGIDLMA-LEQALQEYPVKACWLMTN-SQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWD 299
Cdd:PRK07681 146 LKKENDFLPdLELIPEEIADKAKMMILNfPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVP 225
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 300 R-DDTVLHCSSFSKCL-VPGFRIGWVAGgsHARQIQRL-QLMSTLSTSS--PMQLALVDYLstrRYDAHLRRLRRQLAER 374
Cdd:PRK07681 226 GaKEVGVEINSLSKSYsLAGSRIGYMIG--NEEIVRALtQFKSNTDYGVflPIQKAACAAL---RNGAAFCEKNRGIYQE 300
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446683342 375 KQQAWQTLLRHLPAEVKihHNDSGYFLWLELPEQLDAGELSAKALEHL-ISIAPGKMFSTSG 435
Cdd:PRK07681 301 RRDTLVDGFRTFGWNVD--KPAGSMFVWAEIPKGWTSLSFAYALMDRAnVVVTPGHAFGPHG 360
PRK09276 PRK09276
LL-diaminopimelate aminotransferase; Provisional
146-463 4.75e-09

LL-diaminopimelate aminotransferase; Provisional


Pssm-ID: 181749  Cd Length: 385  Bit Score: 58.00  E-value: 4.75e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQQ-GITVSPDEIVITA-GALEAL-NLSLqAVTAPGDWVVVENPCF--Y--GALQAL---ERLRLKA 215
Cdd:PRK09276  70 GMLEFRKAVADWYKRRfGVELDPETEVISLiGSKEGIaHIPL-AFVNPGDVVLVPDPGYpvYkiGTIFAGgepYFMPLKE 148
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 216 L--------SIPTDVKEGIDLMALEqalqeYPvkacwlmtnsQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYF 287
Cdd:PRK09276 149 EngflpdldAIPEDVAKKAKLMFIN-----YP----------NNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSEIAY 213
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 288 GREKPLP------AKawdrdDTVLHCSSFSKCL-VPGFRIGWVAGgsHARQIQRL-QLMSTLSTSSP--MQLALVDYLST 357
Cdd:PRK09276 214 DGYKPPSflevpgAK-----DVGIEFHSLSKTYnMTGWRIGFAVG--NADLIAGLgKVKSNVDSGVFqaIQEAGIAALNG 286
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 358 RryDAHLRRLRRQLAERKQQAWQTlLRHLPAEVKIhhNDSGYFLWLELPEQLDAGELSAKALEHL-ISIAPGKMFSTSGA 436
Cdd:PRK09276 287 P--QEVVEELRKIYQERRDILVEG-LRKLGLEVEP--PKATFYVWAPVPKGYTSAEFATLLLDKAgVVVTPGNGFGEYGE 361
                        330       340       350
                 ....*....|....*....|....*....|.
gi 446683342 437 wtRFFRF----NTawhwgEREEQAVKQLGSL 463
Cdd:PRK09276 362 --GYFRIaltvPD-----ERIEEAVERIKKL 385
PRK08636 PRK08636
LL-diaminopimelate aminotransferase;
150-435 5.90e-09

LL-diaminopimelate aminotransferase;


Pssm-ID: 236316  Cd Length: 403  Bit Score: 57.79  E-value: 5.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 150 LRYAIARRYAQQ-GITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQA-------LERLRLKaLSIPT 220
Cdd:PRK08636  76 LRLAICNWYKRKyNVDLDPEtEVVATMGSKEGYVHLVQAITNPGDVAIVPDPAYPIHSQAfilaggnVHKMPLE-YNEDF 154
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 221 DVKEGIDLMALEQALQEYPVKACWLMTN-SQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYF-GREKPLPAKAW 298
Cdd:PRK08636 155 ELDEDQFFENLEKALRESSPKPKYVVVNfPHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFdGYKTPSILEVE 234
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 299 DRDDTVLHCSSFSKCL-VPGFRIGWVAGgsHARQIQRLQLMST---LSTSSPMQLAlvdylSTRRYDAHlRRLRRQLAER 374
Cdd:PRK08636 235 GAKDVAVESYTLSKSYnMAGWRVGFVVG--NKKLVGALKKIKSwldYGMFTPIQVA-----ATIALDGD-QSCVEEIRET 306
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446683342 375 KQQAWQTLLRHLP-AEVKIHHNDSGYFLWLELPEQ---LDAGELSAKAL-EHLISIAPGKMFSTSG 435
Cdd:PRK08636 307 YRKRRDVLIESFAnAGWELQKPRASMFVWAKIPEParhLGSLEFSKQLLtEAKVAVSPGIGFGEYG 372
PRK14999 PRK14999
histidine utilization repressor; Provisional
4-87 6.23e-09

histidine utilization repressor; Provisional


Pssm-ID: 184961 [Multi-domain]  Cd Length: 241  Bit Score: 56.48  E-value: 6.23e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   4 YQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVApHPVCRSVATAAHVIR 83
Cdd:PRK14999  14 YETVKQDICKKIAGGVWQPHDRIPSEAELVAQYGFSRMTINRALRELTDEGWLVRLQGVGTFVA-EPKGQSALFEVRSIA 92

                 ....
gi 446683342  84 DEAV 87
Cdd:PRK14999  93 EEIA 96
PRK05957 PRK05957
pyridoxal phosphate-dependent aminotransferase;
140-439 1.17e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235654  Cd Length: 389  Bit Score: 57.00  E-value: 1.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 140 IENLPPgnaeLRYAIARRYAQQ-GITVSPDE-IVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALS 217
Cdd:PRK05957  64 VQGIPP----LLEAITQKLQQDnGIELNNEQaIVVTAGSNMAFMNAILAITDPGDEIILNTPYYFNHEMAITMAGCQPIL 139
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 218 IPTDVKEGIDLMALEQALQEypvKACWLMTNS-QNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPL-PA 295
Cdd:PRK05957 140 VPTDDNYQLQPEAIEQAITP---KTRAIVTISpNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGVKHFsPG 216
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 296 KAWDRDDTVLHCSSFSKCL-VPGFRIGWVAGGSH-ARQIQRLQlmSTLSTSSPM--QLALVDYLSTRRydAHLRRLRRQL 371
Cdd:PRK05957 217 SIPGSGNHTISLYSLSKAYgFASWRIGYMVIPIHlLEAIKKIQ--DTILICPPVvsQYAALGALQVGK--SYCQQHLPEI 292
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446683342 372 AERKQQAWQTLLRhLPAEVKIHHNDSGYFLWLELPEQLDAGELsAKAL--EHLISIAPGKMFS-TSGAWTR 439
Cdd:PRK05957 293 AQVRQILLKSLGQ-LQDRCTLHPANGAFYCFLKVNTDLNDFEL-VKQLirEYRVAVIPGTTFGmKNGCYLR 361
PLN02187 PLN02187
rooty/superroot1
165-324 1.20e-08

rooty/superroot1


Pssm-ID: 215119 [Multi-domain]  Cd Length: 462  Bit Score: 57.04  E-value: 1.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 165 VSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALQALERLRLKALSIPTDVKEGIDLMALEQALQEYPVKA 242
Cdd:PLN02187 129 LTPEDIFLTAGCNQGIEIVFESLARPNANILLPRPGFphYDARAAYSGLEVRKFDLLPEKEWEIDLEGIEAIADENTVAM 208
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 243 cwLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSK-CLVPGFRIG 321
Cdd:PLN02187 209 --VVINPNNPCGNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFGDNPFVSMGKFASIVPVLTLAGISKgWVVPGWKIG 286

                 ...
gi 446683342 322 WVA 324
Cdd:PLN02187 287 WIA 289
PRK05166 PRK05166
histidinol-phosphate transaminase;
119-322 1.51e-08

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 56.30  E-value: 1.51e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 119 PLPQLNRSLAQVSktatamSVIENLP-PGNAELRYAIARRYAqqgitVSPDEIVITAGALEALNLSLQAVTAPGDWVVVE 197
Cdd:PRK05166  50 PSPAVRRAFADIA------ELLRLYPdPQGRALREAIAARTG-----VPADRIILGNGSEDLIAVICRAVLRPGDRVVTL 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 198 NPCF-----YGALQAlerLRLKALSIPTDVkeGIDLMALEQALQEYPVKAcwLMTNSQNPLGFTLSAEKKARLVALLTHH 272
Cdd:PRK05166 119 YPSFplhedYPTMMG---ARVERVTVTPDL--GFDLDALCAAVARAPRML--MFSNPSNPVGSWLTADQLARVLDATPPE 191
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446683342 273 NVMLIeDDVYSELYFGREKPLPA---KAWDRDDTVLHcsSFSKCL-VPGFRIGW 322
Cdd:PRK05166 192 TLIVV-DEAYAEYAAGDDYPSALtllKARGLPWIVLR--TFSKAYgLAGLRVGY 242
PLN00143 PLN00143
tyrosine/nicotianamine aminotransferase; Provisional
165-323 2.53e-08

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 165711 [Multi-domain]  Cd Length: 409  Bit Score: 55.79  E-value: 2.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 165 VSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCF--YGALQALERLRLKALSIPTDVKEGIDLMALEQALQEYPVKA 242
Cdd:PLN00143  95 LSPDDVYLTLGCKHAAEIIIKVLARPEANILLPRPGFpdVETYAIFHHLEIRHFDLLPEKGWEVDLDAVEAIADENTIAM 174
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 243 cwLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSK-CLVPGFRIG 321
Cdd:PLN00143 175 --VIINPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFGSKPFVPMGLFASIVPVITLGSISKrWMIPGWGLG 252

                 ..
gi 446683342 322 WV 323
Cdd:PLN00143 253 WL 254
PRK09147 PRK09147
succinyldiaminopimelate transaminase; Provisional
146-406 5.37e-08

succinyldiaminopimelate transaminase; Provisional


Pssm-ID: 236393  Cd Length: 396  Bit Score: 54.88  E-value: 5.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIA----RRYAQQgiTVSPD-EIVITAGALEALNLSLQAV---TAPGDWVVVENPcFY----GA--LQALERL 211
Cdd:PRK09147  66 GLPALREAIAawleRRYGLP--ALDPAtQVLPVNGSREALFAFAQTVidrDGPGPLVVCPNP-FYqiyeGAalLAGAEPY 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 212 RLKAL----------SIPTDVKEGIDLMALeqalqeypvkaCwlmtNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDV 281
Cdd:PRK09147 143 FLNCDpannfapdfdAVPAEVWARTQLLFV-----------C----SPGNPTGAVLPLDDWKKLFALSDRYGFVIASDEC 207
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 282 YSELYFGREKPLP-----AKAWDRDD----TVLHcsSFSK-CLVPGFRIGWVAGgsHARQIQRLQLMSTL---STSSPMQ 348
Cdd:PRK09147 208 YSEIYFDEAAPPLglleaAAELGRDDfkrlVVFH--SLSKrSNVPGLRSGFVAG--DAALLKKFLLYRTYhgcAMPPAVQ 283
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446683342 349 LAlvdylSTRRYD--AHLRRLRRQLAErKQQAWQTLLrhlpAEV-KIHHNDSGYFLWLELP 406
Cdd:PRK09147 284 AA-----SIAAWNdeAHVRENRALYRE-KFDAVTPIL----APVlDVQLPDAGFYLWAKVP 334
avtA PRK09440
valine--pyruvate transaminase; Provisional
251-407 6.48e-08

valine--pyruvate transaminase; Provisional


Pssm-ID: 236517  Cd Length: 416  Bit Score: 54.48  E-value: 6.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 251 NPLGFTLSAEKKARLVALLTHHNVMLIEDDVYS----ELYFGREKPLpakaWDrdDTVLHCSSFSKCLVPGFRIGWVAGG 326
Cdd:PRK09440 190 NPTGNVLTDEELEKLDALARQHNIPLLIDNAYGppfpGIIFSEATPL----WN--PNIILCMSLSKLGLPGVRCGIVIAD 263
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 327 ShaRQIQRLQLMST---LSTSSPMQLALVDYLStrryDAHLRRLRRQL-----AERKQQAWQTLLRHLPAE-VKIHHNDS 397
Cdd:PRK09440 264 E--EIIEALSNMNGiisLAPGRLGPAIAAEMIE----SGDLLRLSETVirpfyRQKVQLAIALLRRYLPDEpCLIHKPEG 337
                        170
                 ....*....|
gi 446683342 398 GYFLWLELPE 407
Cdd:PRK09440 338 AIFLWLWFKD 347
PRK05942 PRK05942
aspartate aminotransferase; Provisional
144-435 3.38e-07

aspartate aminotransferase; Provisional


Pssm-ID: 180317  Cd Length: 394  Bit Score: 52.41  E-value: 3.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 144 PP--GNAELRYAIARRYAQQ-GITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPC----FYGALQA---LERLR 212
Cdd:PRK05942  70 PPfeGTASFRQAITDWYHRRyGVELDPDsEALPLLGSKEGLTHLALAYVNPGDVVLVPSPAypahFRGPLIAgaqIYPII 149
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 213 LKA--------LSIPTDVKEGIDLMALEqalqeYPvkacwlmtnsQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSE 284
Cdd:PRK05942 150 LKPendwlidlSSIPEEVAQQAKILYFN-----YP----------SNPTTATAPREFFEEIVAFARKYEIMLVHDLCYAE 214
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 285 LYFGREKP-----LP-AKawdrdDTVLHCSSFSKCL-VPGFRIGWVAGGSHArqIQRLQlmsTLSTS------SPMQLAL 351
Cdd:PRK05942 215 LAFDGYQPtslleIPgAK-----DIGVEFHTLSKTYnMAGWRVGFVVGNRHI--IQGLR---TLKTNldygifSALQKAA 284
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 352 VDYLSTRryDAHLrrlrRQLAERKQQAWQTLLRHLpAEV--KIHHNDSGYFLWLELPEQLDAGELSAKALEHL-ISIAPG 428
Cdd:PRK05942 285 ETALQLP--DSYL----QQVQERYRTRRDFLIQGL-GELgwNIPPTKATMYLWVPCPVGMGSTDFALNVLQKTgVVVTPG 357

                 ....*..
gi 446683342 429 KMFSTSG 435
Cdd:PRK05942 358 NAFGEGG 364
PRK11523 PRK11523
transcriptional regulator ExuR;
4-110 1.43e-06

transcriptional regulator ExuR;


Pssm-ID: 183176 [Multi-domain]  Cd Length: 253  Bit Score: 49.46  E-value: 1.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   4 YQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAphpvcrSVATAAHVIR 83
Cdd:PRK11523  10 YQQLAAELKERIEQGVYLVGDKLPAERFIADEKNVSRTVVREAIIMLEVEGYVEVRKGSGIHVV------SNQPRHQQAA 83
                         90       100       110
                 ....*....|....*....|....*....|
gi 446683342  84 DEAVDINTY-IFEMLQASR--DTSVVPFAS 110
Cdd:PRK11523  84 DNNMEFANYgPFELLQARQliESNIAEFAA 113
PRK07366 PRK07366
LL-diaminopimelate aminotransferase;
146-464 2.09e-06

LL-diaminopimelate aminotransferase;


Pssm-ID: 180947  Cd Length: 388  Bit Score: 49.68  E-value: 2.09e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIARRYAQQ-GITVSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENP---------------CFYGALQAl 208
Cdd:PRK07366  69 GTLDFREAAAQWYEQRfGLAVDPEtEVLPLIGSQEGTAHLPLAVLNPGDFALLLDPgypshaggvylaggqIYPMPLRA- 147
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 209 ERLRLKALS-IPTDVKEGIDLMALEqalqeYPVKAcwlmTNSQNPLGFTLSAekkarlVALLTHHNVMLIEDDVYSELYF 287
Cdd:PRK07366 148 ENDFLPVFAdIPTEVLAQARLMVLS-----YPHNP----TTAIAPLSFFQEA------VAFCQQHDLVLVHDFPYVDLVF 212
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 288 GREKPLPA--KAwDRDDTV-LHCSSFSKCL-VPGFRIGWVAGgsHARQIQRLQLMStlstsspmqlALVDY--------- 354
Cdd:PRK07366 213 DGEVEPPSilQA-DPEKSVsIEFFTLSKSYnMGGFRIGFAIG--NAQLIQALRQVK----------AVVDFnqyrgilng 279
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 355 --LSTRRYDAHLRRLRRQLAERKQQAWQTLLRH-----LPAevkihhndSGYFLWLELPE--QLDAGELSAKALEHL-IS 424
Cdd:PRK07366 280 aiAALTGPQATVQQTVQIFRQRRDAFINALHQIgwpvpLPE--------ATMYVWAKLPEpwQGNSVEFCTQLVAQTgVA 351
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 446683342 425 IAPGKMFSTSG-AWTRFfrfnTAWHWGEREEQAVKQLGSLI 464
Cdd:PRK07366 352 ASPGSGFGKSGeGYVRF----ALVHDPDILEEAVERIAAFL 388
PRK05839 PRK05839
succinyldiaminopimelate transaminase;
146-325 2.76e-06

succinyldiaminopimelate transaminase;


Pssm-ID: 180281  Cd Length: 374  Bit Score: 49.30  E-value: 2.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYA----IARRYaqqGITVSPDEIVITAGALEAL-NLSLQAV-TAPGDWVVVENPcFY----GALQALerlRLKA 215
Cdd:PRK05839  61 GEESLREAqrgfFKRRF---KIELKENELIPTFGTREVLfNFPQFVLfDKQNPTIAYPNP-FYqiyeGAAIAS---RAKV 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 216 LSIP----TDVKEGIDlmalEQALQEypvkACWLMTNS-QNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGRE 290
Cdd:PRK05839 134 LLMPltkeNDFTPSLN----EKELQE----VDLVILNSpNNPTGRTLSLEELIEWVKLALKHDFILINDECYSEIYENTP 205
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 446683342 291 KP--LPA--KAWDRD-DTVLHCSSFSKCL-VPGFRIGWVAG 325
Cdd:PRK05839 206 PPslLEAsiLVGNESfKNVLVINSISKRSsAPGLRSGFIAG 246
PRK09764 PRK09764
GntR family transcriptional regulator;
3-66 2.98e-06

GntR family transcriptional regulator;


Pssm-ID: 182065 [Multi-domain]  Cd Length: 240  Bit Score: 48.29  E-value: 2.98e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446683342   3 KYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYV 66
Cdd:PRK09764   6 LYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYV 69
GntR COG1802
DNA-binding transcriptional regulator, GntR family [Transcription];
5-68 3.20e-06

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441407 [Multi-domain]  Cd Length: 222  Bit Score: 47.99  E-value: 3.20e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446683342   5 QRLAEQIREQIASGVWQPGDRLpSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAP 68
Cdd:COG1802   14 EQVYEALREAILSGELPPGERL-SEAELAERLGVSRTPVREALRRLEAEGLVEIRPNRGARVAP 76
PRK10225 PRK10225
Uxu operon transcriptional regulator;
2-110 1.25e-05

Uxu operon transcriptional regulator;


Pssm-ID: 182318 [Multi-domain]  Cd Length: 257  Bit Score: 46.55  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342   2 KKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHPVCRSVATA-AH 80
Cdd:PRK10225   9 RPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSHNTDSPdAN 88
                         90       100       110
                 ....*....|....*....|....*....|..
gi 446683342  81 VIRDEAVdintyiFEMLQASR--DTSVVPFAS 110
Cdd:PRK10225  89 VCNDAGP------FELLQARQllESNIAEFAA 114
PRK10421 PRK10421
DNA-binding transcriptional repressor LldR; Provisional
6-70 8.65e-05

DNA-binding transcriptional repressor LldR; Provisional


Pssm-ID: 236690 [Multi-domain]  Cd Length: 253  Bit Score: 43.99  E-value: 8.65e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446683342   6 RLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSGYYVAPHP 70
Cdd:PRK10421   6 EVADRVRALIEEKNLEAGMKLPAERQLAMQLGVSRNSLREALAKLVSEGVLLSRRGGGTFIRWRH 70
PRK06290 PRK06290
LL-diaminopimelate aminotransferase;
146-328 1.85e-04

LL-diaminopimelate aminotransferase;


Pssm-ID: 235772  Cd Length: 410  Bit Score: 43.87  E-value: 1.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 146 GNAELRYAIA----RRYAQQGItvSPD-EIVITAGALEALNLSLQAVTAPGDWVVVENPCF---------YGAlqALERL 211
Cdd:PRK06290  82 GIQEFKEAAArymeKVFGVKDI--DPVtEVIHSIGSKPALAMLPSCFINPGDVTLMTVPGYpvtgthtkyYGG--EVYNL 157
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 212 RLKA--------LSIPTDVKEGIDLMALEqalqeYPvkacwlmtnsQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYS 283
Cdd:PRK06290 158 PLLEennflpdlDSIPKDIKEKAKLLYLN-----YP----------NNPTGAVATKEFYEEVVDFAKENNIIVVQDAAYA 222
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446683342 284 ELYFGrEKPLP------AKawdrdDTVLHCSSFSKCL-VPGFRIGWVAGGSH 328
Cdd:PRK06290 223 ALTFD-GKPLSflsvpgAK-----EVGVEIHSLSKAYnMTGWRLAFVVGNEL 268
PTZ00377 PTZ00377
alanine aminotransferase; Provisional
145-292 2.16e-04

alanine aminotransferase; Provisional


Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 43.41  E-value: 2.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 145 PGNAELRYAIARrYAQQ--GITVSPDEIVITAGALEALNLSLQAVTA-PGDWVVVENPCF--YGALQALerlrLKALSIP 219
Cdd:PTZ00377 115 AGYPFVRKAVAA-FIERrdGVPKDPSDIFLTDGASSGIKLLLQLLIGdPSDGVMIPIPQYplYSAAITL----LGGKQVP 189
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 220 TDVKE----GIDLMALEQALQEYPVKA----CWLMTNSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREK 291
Cdd:PTZ00377 190 YYLDEekgwSLDQEELEEAYEQAVRNGitprALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQENIYDGEK 269

                 .
gi 446683342 292 P 292
Cdd:PTZ00377 270 P 270
PRK08354 PRK08354
putative aminotransferase; Provisional
169-325 2.66e-04

putative aminotransferase; Provisional


Pssm-ID: 169399  Cd Length: 311  Bit Score: 42.79  E-value: 2.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 169 EIVITAGALEALNLsLQAVTAPGDWVVVENPCfYGalqALERL-RLKALSIptdVKEGIDLMALEQALQEYPVKacwLMT 247
Cdd:PRK08354  56 PIVITAGITEALYL-IGILALRDRKVIIPRHT-YG---EYERVaRFFAARI---IKGPNDPEKLEELVERNSVV---FFC 124
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446683342 248 NSQNPLGFTLSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKPlpakawDRDDTVLhCSSFSKCL-VPGFRIGWVAG 325
Cdd:PRK08354 125 NPNNPDGKFYNFKELKPLLDAVEDRNALLILDEAFIDFVKKPESP------EGENIIK-LRTFTKSYgLPGIRVGYVKG 196
PLN02368 PLN02368
alanine transaminase
114-292 8.38e-04

alanine transaminase


Pssm-ID: 177996 [Multi-domain]  Cd Length: 407  Bit Score: 41.71  E-value: 8.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 114 DPR---LFPLPQLNRS---LAQVSKTATAMSVIENLPPGNAELRYAIARRyaqQGITVSPDEIVITAGALEALNLSLQAV 187
Cdd:PLN02368  74 DPNvglLFPADAIARAkhyLSLTSGGLGAYSDSRGLPGVRKEVAEFIERR---DGYPSDPELIFLTDGASKGVMQILNAV 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 188 T-APGDWVVVENPCF--YGALQALerlrLKALSIPTDVKE----GIDLMALEQALQEYPVKA----CWLMTNSQNPLGFT 256
Cdd:PLN02368 151 IrGEKDGVLVPVPQYplYSATISL----LGGTLVPYYLEEsenwGLDVNNLRQSVAQARSKGitvrAMVIINPGNPTGQC 226
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 446683342 257 LSAEKKARLVALLTHHNVMLIEDDVYSELYFGREKP 292
Cdd:PLN02368 227 LSEANLREILKFCYQERLVLLGDEVYQQNIYQDERP 262
AAT_I cd01494
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ...
155-282 9.97e-04

Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).


Pssm-ID: 99742 [Multi-domain]  Cd Length: 170  Bit Score: 40.06  E-value: 9.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 155 ARRYAQQGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQ-ALERLRLKALSIPTDVKE--GIDLMAL 231
Cdd:cd01494    5 LEEKLARLLQPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSRYWvAAELAGAKPVPVPVDDAGygGLDVAIL 84
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446683342 232 EQALQEYPVKACWLMTNSQNPLGFTLSAEkkarLVALLTHHNVMLIEDDVY 282
Cdd:cd01494   85 EELKAKPNVALIVITPNTTSGGVLVPLKE----IRKIAKEYGILLLVDAAS 131
PRK09265 PRK09265
aminotransferase AlaT; Validated
139-350 7.85e-03

aminotransferase AlaT; Validated


Pssm-ID: 181738  Cd Length: 404  Bit Score: 38.64  E-value: 7.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 139 VIENLPpgNAE----------LRYAIARRYAQQGIT-VSPDEIVITAGALEALNLSLQAVTAPGDWVVVENP-------- 199
Cdd:PRK09265  58 VIRNLP--TAQgysdskglfsARKAIMQYYQQKGIPdVDVDDIYIGNGVSELIVMAMQALLNNGDEVLVPAPdyplwtaa 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 200 ------------C-----FYGALQALERL---RLKALSIptdvkegidlmaleqalqeypvkacwlmTNSQNPLGFTLSA 259
Cdd:PRK09265 136 vslsggkpvhylCdeeagWFPDLDDIRSKitpRTKAIVI----------------------------INPNNPTGAVYSK 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446683342 260 EKKARLVALLTHHNVMLIEDDVYSE-LYFGREK-PLPAKAwdrdDTVLhCSSF---SKCL-VPGFRIGW--VAGG-SHAR 330
Cdd:PRK09265 188 ELLEEIVEIARQHNLIIFADEIYDKiLYDGAVHiSIASLA----PDLL-CVTFnglSKAYrVAGFRVGWmvLSGPkKHAK 262
                        250       260
                 ....*....|....*....|...
gi 446683342 331 Q-IQRLQLMST--LSTSSPMQLA 350
Cdd:PRK09265 263 GyIEGLDMLASmrLCANVPAQHA 285
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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