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Conserved domains on  [gi|446684435|ref|WP_000761781|]
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DUF927 domain-containing protein [Escherichia coli]

Protein Classification

DUF927 domain-containing protein( domain architecture ID 10009384)

DUF927 domain-containing protein similar to Staphylococcus aureus MCM-like replicative helicase

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG5519 COG5519
Predicted ATPase domain of Cch-like helicases, DUF927 family [General function prediction only] ...
224-710 0e+00

Predicted ATPase domain of Cch-like helicases, DUF927 family [General function prediction only];


:

Pssm-ID: 444270 [Multi-domain]  Cd Length: 592  Bit Score: 637.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 224 GDRDGWRLLKDHGLNVTTNGKYRAILADWMQLSGSHEEWQLSTTTGWHFGAYIMPDGsIIGESEKPILFTGKSAAINGYS 303
Cdd:COG5519  103 AGGELRRELLAKGLTITTNRKARALLADYLQRSGPKRRARCVTRTGWHGGAFVLPDE-VIGTPEEPVIFQGRSAAAAGYA 181
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 304 VAGTADGWRDSVARLAGGNASMILGVATSLAAPLIGLVGADGFGVHLFEQSSAGKTTTQNIASSLWGEPDAQRLTWYGTA 383
Cdd:COG5519  182 VAGTLEDWREEVAALAVGNSRLMLALSAAFAGPLLELLGAEGGGFHLYGDSSTGKTTALNVAASVWGGPDGFRRTWRATA 261
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 384 LGIANEAEAHNDGLLPLDEIGQAgNAREVSTSAYTLFNGSGKLQGAKDGGNREIKHWRTVAISTGEMDVETFLKSEGIKV 463
Cdd:COG5519  262 NGLEGEAAAHNDGLLALDEIGQA-DPKEAGQIAYMLANGQGKARATKDGGARAVARWRTLFLSTGEVSLETHMAEAGKRT 340
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 464 KAGQLVRLLNVPMEKAT-----KFHEYSNGKEHADALKDAWTANHGAAGREWVKWLAGHQQEAKDTVRECRERWRN-LIP 537
Cdd:COG5519  341 KAGQEVRLLDIPADAGKhgafeNLHGFTDGAALADALKRAAAQHYGHAGRAFLEYLTKDRQDLAELLRELKDRFLAlLLP 420
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 538 ESYGEQVHRVGERFAILEAALVLSGH--VTGWVVQECRDAIQHNFNAWVKEFGTGNREFKQMVEQAEAFLSSFGFSRYLP 615
Cdd:COG5519  421 ADASGQVRRVAERFALVAAAGELATEagITGWPEGEALDAAQECFNAWLAARGGGNKEDRQALEQVRAFIERHGDSRFAD 500
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 616 HPnTDERDLPIKELAGYRKgsIRNEDDEMRYYTFPHVFESEIAKGFNPAHFARALDAAGMLEKGSD-RRYKKKALGKIGG 694
Cdd:COG5519  501 WD-DDDQDPRVRDRAGYRR--VEDEDGGREYLVLPEGFKKEICKGFDPKRAARVLAEAGWLKPGKDgKRTRKRRLPGRGG 577
                        490
                 ....*....|....*.
gi 446684435 695 KQhvFYVLMFQPDDED 710
Cdd:COG5519  578 VR--VYVVRPDVLGGE 591
 
Name Accession Description Interval E-value
COG5519 COG5519
Predicted ATPase domain of Cch-like helicases, DUF927 family [General function prediction only] ...
224-710 0e+00

Predicted ATPase domain of Cch-like helicases, DUF927 family [General function prediction only];


Pssm-ID: 444270 [Multi-domain]  Cd Length: 592  Bit Score: 637.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 224 GDRDGWRLLKDHGLNVTTNGKYRAILADWMQLSGSHEEWQLSTTTGWHFGAYIMPDGsIIGESEKPILFTGKSAAINGYS 303
Cdd:COG5519  103 AGGELRRELLAKGLTITTNRKARALLADYLQRSGPKRRARCVTRTGWHGGAFVLPDE-VIGTPEEPVIFQGRSAAAAGYA 181
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 304 VAGTADGWRDSVARLAGGNASMILGVATSLAAPLIGLVGADGFGVHLFEQSSAGKTTTQNIASSLWGEPDAQRLTWYGTA 383
Cdd:COG5519  182 VAGTLEDWREEVAALAVGNSRLMLALSAAFAGPLLELLGAEGGGFHLYGDSSTGKTTALNVAASVWGGPDGFRRTWRATA 261
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 384 LGIANEAEAHNDGLLPLDEIGQAgNAREVSTSAYTLFNGSGKLQGAKDGGNREIKHWRTVAISTGEMDVETFLKSEGIKV 463
Cdd:COG5519  262 NGLEGEAAAHNDGLLALDEIGQA-DPKEAGQIAYMLANGQGKARATKDGGARAVARWRTLFLSTGEVSLETHMAEAGKRT 340
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 464 KAGQLVRLLNVPMEKAT-----KFHEYSNGKEHADALKDAWTANHGAAGREWVKWLAGHQQEAKDTVRECRERWRN-LIP 537
Cdd:COG5519  341 KAGQEVRLLDIPADAGKhgafeNLHGFTDGAALADALKRAAAQHYGHAGRAFLEYLTKDRQDLAELLRELKDRFLAlLLP 420
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 538 ESYGEQVHRVGERFAILEAALVLSGH--VTGWVVQECRDAIQHNFNAWVKEFGTGNREFKQMVEQAEAFLSSFGFSRYLP 615
Cdd:COG5519  421 ADASGQVRRVAERFALVAAAGELATEagITGWPEGEALDAAQECFNAWLAARGGGNKEDRQALEQVRAFIERHGDSRFAD 500
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 616 HPnTDERDLPIKELAGYRKgsIRNEDDEMRYYTFPHVFESEIAKGFNPAHFARALDAAGMLEKGSD-RRYKKKALGKIGG 694
Cdd:COG5519  501 WD-DDDQDPRVRDRAGYRR--VEDEDGGREYLVLPEGFKKEICKGFDPKRAARVLAEAGWLKPGKDgKRTRKRRLPGRGG 577
                        490
                 ....*....|....*.
gi 446684435 695 KQhvFYVLMFQPDDED 710
Cdd:COG5519  578 VR--VYVVRPDVLGGE 591
DUF927 pfam06048
Domain of unknown function (DUF927); This entry represents a domain found in bacterial ...
160-439 7.24e-48

Domain of unknown function (DUF927); This entry represents a domain found in bacterial proteins of unknown function. The crystal structure has been solved for a protein containing this domain SWISS:Q0WXP6.


Pssm-ID: 428740  Cd Length: 286  Bit Score: 170.60  E-value: 7.24e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435  160 DGVfWVTpKVDKQSGEIIRPETWLCSPLELLGTG-TIGKEHY-RVMRWKKTANHE---VITMAIPCGGigDRDGWRLLKD 234
Cdd:pfam06048   6 DGI-WKY-GIKKDKEGLPPEKVWVCTPIHISARTrDPDDETEgRLLEWRDVDGKWkewVMPAALLSGD--GSDLRKELAD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435  235 HGLnvTTNGKYRAILADW-MQLSGSHEEWQLSTTTGWH--FGAYIMPDGSIIGESEKPILFTGKSAAINGYSVAGTADGW 311
Cdd:pfam06048  82 LGL--TIISPNAKDLAKYlQQLEDPLPRVRCVDRVGWHkdGGVFVLGDEVIGTDGEKDIIFQDEEYITSGYSQKGTLDEW 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435  312 RDSVARLAGGNASMILGVATSLAAPLIGLVGADGFGVHLFEQSSAGKTTTQNIASSLWGEPDAQRLTWYGTALGIANEAE 391
Cdd:pfam06048 160 RREIAALCRGNSRLVLAVSSALAAPLLKIIGAEGGGFHFYGQSSTGKTTALRLAASVWGNPEGLIRSWNATANGLEGLAA 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 446684435  392 AHNDGLLPLDEIGQAgNAREVSTSAYTLFNGSGKLQGAKDGGNREIKH 439
Cdd:pfam06048 240 LNNDVPLILDEISQA-DPREAGGLVYMLANGQGKGRANRTGTARTPKR 286
 
Name Accession Description Interval E-value
COG5519 COG5519
Predicted ATPase domain of Cch-like helicases, DUF927 family [General function prediction only] ...
224-710 0e+00

Predicted ATPase domain of Cch-like helicases, DUF927 family [General function prediction only];


Pssm-ID: 444270 [Multi-domain]  Cd Length: 592  Bit Score: 637.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 224 GDRDGWRLLKDHGLNVTTNGKYRAILADWMQLSGSHEEWQLSTTTGWHFGAYIMPDGsIIGESEKPILFTGKSAAINGYS 303
Cdd:COG5519  103 AGGELRRELLAKGLTITTNRKARALLADYLQRSGPKRRARCVTRTGWHGGAFVLPDE-VIGTPEEPVIFQGRSAAAAGYA 181
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 304 VAGTADGWRDSVARLAGGNASMILGVATSLAAPLIGLVGADGFGVHLFEQSSAGKTTTQNIASSLWGEPDAQRLTWYGTA 383
Cdd:COG5519  182 VAGTLEDWREEVAALAVGNSRLMLALSAAFAGPLLELLGAEGGGFHLYGDSSTGKTTALNVAASVWGGPDGFRRTWRATA 261
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 384 LGIANEAEAHNDGLLPLDEIGQAgNAREVSTSAYTLFNGSGKLQGAKDGGNREIKHWRTVAISTGEMDVETFLKSEGIKV 463
Cdd:COG5519  262 NGLEGEAAAHNDGLLALDEIGQA-DPKEAGQIAYMLANGQGKARATKDGGARAVARWRTLFLSTGEVSLETHMAEAGKRT 340
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 464 KAGQLVRLLNVPMEKAT-----KFHEYSNGKEHADALKDAWTANHGAAGREWVKWLAGHQQEAKDTVRECRERWRN-LIP 537
Cdd:COG5519  341 KAGQEVRLLDIPADAGKhgafeNLHGFTDGAALADALKRAAAQHYGHAGRAFLEYLTKDRQDLAELLRELKDRFLAlLLP 420
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 538 ESYGEQVHRVGERFAILEAALVLSGH--VTGWVVQECRDAIQHNFNAWVKEFGTGNREFKQMVEQAEAFLSSFGFSRYLP 615
Cdd:COG5519  421 ADASGQVRRVAERFALVAAAGELATEagITGWPEGEALDAAQECFNAWLAARGGGNKEDRQALEQVRAFIERHGDSRFAD 500
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435 616 HPnTDERDLPIKELAGYRKgsIRNEDDEMRYYTFPHVFESEIAKGFNPAHFARALDAAGMLEKGSD-RRYKKKALGKIGG 694
Cdd:COG5519  501 WD-DDDQDPRVRDRAGYRR--VEDEDGGREYLVLPEGFKKEICKGFDPKRAARVLAEAGWLKPGKDgKRTRKRRLPGRGG 577
                        490
                 ....*....|....*.
gi 446684435 695 KQhvFYVLMFQPDDED 710
Cdd:COG5519  578 VR--VYVVRPDVLGGE 591
DUF927 pfam06048
Domain of unknown function (DUF927); This entry represents a domain found in bacterial ...
160-439 7.24e-48

Domain of unknown function (DUF927); This entry represents a domain found in bacterial proteins of unknown function. The crystal structure has been solved for a protein containing this domain SWISS:Q0WXP6.


Pssm-ID: 428740  Cd Length: 286  Bit Score: 170.60  E-value: 7.24e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435  160 DGVfWVTpKVDKQSGEIIRPETWLCSPLELLGTG-TIGKEHY-RVMRWKKTANHE---VITMAIPCGGigDRDGWRLLKD 234
Cdd:pfam06048   6 DGI-WKY-GIKKDKEGLPPEKVWVCTPIHISARTrDPDDETEgRLLEWRDVDGKWkewVMPAALLSGD--GSDLRKELAD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435  235 HGLnvTTNGKYRAILADW-MQLSGSHEEWQLSTTTGWH--FGAYIMPDGSIIGESEKPILFTGKSAAINGYSVAGTADGW 311
Cdd:pfam06048  82 LGL--TIISPNAKDLAKYlQQLEDPLPRVRCVDRVGWHkdGGVFVLGDEVIGTDGEKDIIFQDEEYITSGYSQKGTLDEW 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446684435  312 RDSVARLAGGNASMILGVATSLAAPLIGLVGADGFGVHLFEQSSAGKTTTQNIASSLWGEPDAQRLTWYGTALGIANEAE 391
Cdd:pfam06048 160 RREIAALCRGNSRLVLAVSSALAAPLLKIIGAEGGGFHFYGQSSTGKTTALRLAASVWGNPEGLIRSWNATANGLEGLAA 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 446684435  392 AHNDGLLPLDEIGQAgNAREVSTSAYTLFNGSGKLQGAKDGGNREIKH 439
Cdd:pfam06048 240 LNNDVPLILDEISQA-DPREAGGLVYMLANGQGKGRANRTGTARTPKR 286
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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