|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15313 |
PRK15313 |
intestinal colonization autotransporter adhesin MisL; |
109-882 |
3.06e-127 |
|
intestinal colonization autotransporter adhesin MisL;
Pssm-ID: 237940 [Multi-domain] Cd Length: 955 Bit Score: 406.49 E-value: 3.06e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 109 ILQGNNT-IVTTGDYSIGLLSQTNGNLntdtiIRVNTDGSVNphlsdegntfivTAGNHAVGVLACASpgsaracvssld 187
Cdd:PRK15313 219 IVVGNRAhIVTTGDSSEGLRTGQSGSL-----IRLGDDATIE------------TSGASSTGIYAASS------------ 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 188 eeSTADTGSNennakakldmakGEITTHGTESYAAYANGTVVKAGSkldytNASVTltdvdITTHGDNAHAIAARQGTVS 267
Cdd:PRK15313 270 --SRTELGNN------------ATITVNGASAHAVYATNATVNLGE-----NATIS-----VNSASKAASYSKAPAGLYA 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 268 FNQGEIHTTGPDAAIAKIYNGGKvtlknTSAVAHQGAGIVlESSINGQEATVDILSGSSLRSANEILYNKNETSNVTITD 347
Cdd:PRK15313 326 LSRGAINLAGGAAITMAGDNSSE-----SYAISTETGGIV-DGSSGGRFVIDGDIRAAGATAASGTLPQQNSTIKLNMTD 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 348 sevssaadvfinnikghlaidasNSKITGSANLSTDDSTHTYLSLS-DNSTWDIKTDSTVSKLTVDN-STVYISRADGKA 425
Cdd:PRK15313 400 -----------------------NSRWDGASYITSATAGTGVISVQmSDATWNMTSSSTLTDLTLNSgATINFSHEDGEP 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 426 FEPtrLTITENYVGNNGILHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEFIKDS 505
Cdd:PRK15313 457 WQT--LTINEDYVGNGGKLVFNTVLNDDDSETDRLQVLGNTSGNTFVAVNNIGGAGAQTIEGIEIVNVAGNSNGTFEKAS 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 506 RIFAGAYEYsltrgNTEATNKNWYLTNFqaTSGGETNSGGSSAPT----VAPTPV------------------------- 556
Cdd:PRK15313 535 RIVAGAYDY-----NVVQKGKNWYLTSY--IEPDEPIIPDPVDPVipdpVIPDPVdpdpvdpvipdpvipdpvdpdpvdp 607
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 557 ---------------------------LRPEAGSYVANLAAANTLFVMRLNDRAGETRYIDPVTEQERSSRLWLRQIGGH 609
Cdd:PRK15313 608 epvdpvipdptipdigqsdtppitehqFRPEVGSYLANNYAANTLFMTRLHDRLGETQYTDMLTGEKKVTSLWMRNVGAH 687
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 610 NAWRDSNGQLRTTSHRYVSQLGAELLTGGFTDSDSWRLGVMAGYARDYNSTHSSVSDYRSKGSVRGYSAGLYATWFADDI 689
Cdd:PRK15313 688 TRFNDGSGQLKTRINSYVLQLGGDLAQWSTDGLDRWHIGAMAGYANSQNRTLSSVSDYHSRGQVTGYSVGLYGTWYANNI 767
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 690 SKKGAYIDAWAQYSWFKNSVKGDELAYESYSAKGATVSLEAGYGFALNksfglEAAKYTWIFQPQAQAIWMGVDHNAHTE 769
Cdd:PRK15313 768 DRSGAYVDTWMLYNWFDNKVMGQDQAAEKYKSKGITASVEAGYSFRLG-----ESAHQSYWLQPKAQVVWMGVQADDNRE 842
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 770 ANGSRIENDANNNFQTRLGFRTFIRTQEKNSGPHGDDFEPFVEMNWIHNSKDFAVSMNGVKVEQDGARNLGEIKLGVNGN 849
Cdd:PRK15313 843 ANGTLVKDDTAGNLLTRMGVKAYINGHNAIDDNKSREFQPFVEANWIHNTQPASVKMDDVSSDMRGTKNIGELKVGIEGQ 922
|
810 820 830
....*....|....*....|....*....|...
gi 446691189 850 LNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF 882
Cdd:PRK15313 923 ITPRLNVWGNVAQQVGDQGYSNTQGLLGVKYSF 955
|
|
| AidA |
COG3468 |
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ... |
35-882 |
1.51e-124 |
|
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain] Cd Length: 846 Bit Score: 396.24 E-value: 1.51e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 35 AVAIKDGEVKDIDNALVITTGNGSYGVSVAGEGSNLTINKGVIVTTGGLYPSGNSPLSTVYTASAVVSEYGGAVILQGNN 114
Cdd:COG3468 28 GGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAGSGGTGGNSTGGGGGNSGTGGTGGGGGG 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 115 TIVTTGDYSIGLLSQTNGN-LNTDTIIRVNTDGSVNPHLSDEGNTFIVTAGNHAVGVLACASPGSARACVSSLDEESTAD 193
Cdd:COG3468 108 GGSGNGGGGGGGGGGGGTGgGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGTGSGGGGSGGGGGAGGGGGGGAGGSGG 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 194 TGSNENNAKAKLDMAKGEITTHGTESYAAYANGTVVKAGSKLDYTNASVTLTDVDITTHGDNAHAIAARQGTVSFNQGEI 273
Cdd:COG3468 188 AGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGGGGSAGGTGGGGLTGGGAAGTGGGGGG 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 274 HTTGPDAAIAKIYNGGKVTLKNTSAVAhqGAGIVLESSINGQEATVDILSGSSLRSANEILYNKNETSNVTITDSEVSSA 353
Cdd:COG3468 268 TGTGSGGGGGGGANGGGSGGGGGASGT--GGGGTASTGGGGGGGGGNGGGGGGGSNAGGGSGGGGGGGGGGGGGGTTLNG 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 354 ADVFINNIKGHLAIDASNSKITGSANLSTDDSTHTYLSLSDNSTWDIKTDSTVSKLTVDNSTVYISRADGKAFEPTRLTI 433
Cdd:COG3468 346 AGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGTGNNGGGGVGGGGGGGLTLTGGTLTV 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 434 TENYVGNNGILHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEFIKDSRIFAGAYE 513
Cdd:COG3468 426 NGNYTGNNGTLVLNTVLGDDNSPTDRLVVNGNTSGTTGVRVNNAGGLGAQTVNGIEVVEVNGASDGAFTLGGRVVAGAYE 505
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 514 YSLTRGNTEATNKNWYLTNfqatsggetnsggSSAPTVAPTPVLRPEAGSYVANLAAANTLFVM-RLNDRAGETRYIDpv 592
Cdd:COG3468 506 YTLYQGGSGGDDGNWYLRS-------------TLTPPDPPTPVYRPEVPSYLANPAAANGLFELgTLHDRLGERRYTD-- 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 593 TEQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGGfTDSDSWRLGVMAGYARDYNSTHSSVSdYRSKGS 672
Cdd:COG3468 571 TGESDNSGAWLRVEGGHNRSRDSSGQLDYDSNRYGLQLGGDLLQWE-DGGGRLHVGVMAGYGNGDSDVRSRAT-GTGKGD 648
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 673 VRGYSAGLYATWFADDiskkGAYIDAWAQYSWFKNSVKGDELAY--ESYSAKGATVSLEAGYGFALNKSfgleaakytWI 750
Cdd:COG3468 649 VDGYSLGLYGTWYGNN----GFYVDGVLQYSWFDNDVSSDDLGGvtGSYDGNGYSASLEAGYPFKLGEG---------WS 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 751 FQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLGFRTFIRTQEKNSGPhgddFEPFVEMNWIHN-SKDFAVSMNGV 829
Cdd:COG3468 716 LEPQAQLIYQGVDFDDFTDSNGTRVSGDDGDSLQGRLGLRLGYEFHWDDGRA----LQPYLEANWLHEfLGDNSVTVNGV 791
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*
gi 446691189 830 KVEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYN--DTAVMVGLKYKF 882
Cdd:COG3468 792 SFSQDGSGTWGELGLGVTGQLNKNLSLYGDVGYQTGLDGYDssDTSGNLGVRYSF 846
|
|
| autotrans_barl |
TIGR01414 |
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ... |
430-882 |
1.59e-96 |
|
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain] Cd Length: 431 Bit Score: 309.31 E-value: 1.59e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 430 RLTITENYVGNNGIlHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEF-IKDSRIF 508
Cdd:TIGR01414 7 TLTVNGLYTGNGGF-VMNTDLGGDNSQTDRLVVNGNASGTTGVVVNNIGGEGAQTGDGITLVTVNGGSDAAFtLANGKVD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 509 AGAYEYSLTRGNTEATNkNWYLTnfqatsggeTNSGGSSAPTVAPTPVLRPEAGSYVANLAAANTLF-VMRLNDRAGETR 587
Cdd:TIGR01414 86 AGAYTYTLYKNGTEDNN-NWYLT---------SSLPDLTPPGQQLSPTYRAEAGSYAANANAALFLAeLDTLRQRMGDLR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 588 YIDpvteQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGGFTDSDsWRLGVMAGYARdyNSTHSSVSDY 667
Cdd:TIGR01414 156 SAA----RDAGNGVWARIFGGDNHLDGDAGAAGYDQNTTGVQLGGDILLAGNADGD-LHVGLMAGYAK--ADIKTRSYKY 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 668 RSKGSVRGYSAGLYATWFADDiskkGAYIDAWAQYSWFKNSVKGDEL---AYESYSAKGATVSLEAGYGFALnksfglea 744
Cdd:TIGR01414 229 GGKGKVDGYGLGLYGTWLQDS----GAYVDGVLQYSRFRNDVSSTGSngkVSGKYNSNGFTASLEAGYRYNL-------- 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 745 AKYTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLGFRtFIRTQEKNSgphGDDFEPFVEMNWIHNSKD-FA 823
Cdd:TIGR01414 297 GGNGWYVEPQAQLSYFGVSGDDYKESNGTRVLGGGGDSLQGRLGLR-VGYQFDLGT---GRAVKPYLKANVLHEFKGgTG 372
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 446691189 824 VSMNGVKVEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF 882
Cdd:TIGR01414 373 VRVNGVTIRNDFSGTRAEYGVGVNAKIKDNLSLYADVDYQKGGKKYTDNQGNLGVRYSF 431
|
|
| auto_AIDA-I |
NF033176 |
autotransporter adhesin AIDA-I; |
213-882 |
2.89e-78 |
|
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain] Cd Length: 1287 Bit Score: 277.31 E-value: 2.89e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 213 TTHGTESYAAY------ANGTVVKAGSKLDYTNASvTLTDVDITTHG----DNAHAIaarQGTVSFNQGEIhttgpdAAI 282
Cdd:NF033176 638 TVTGTNHYGSFsvsqnhASNVVLENGGLLAVTSGS-TATDTTVNSAGrlriDEGGAL---DGTTTINADGI------VAG 707
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 283 AKIYNGGKVTLKNT------SAVAHQGAGIVLESSINGQEATVDILSGSSLRSANEILYNKNETSNVTITDSEVSSAAD- 355
Cdd:NF033176 708 AKIKNDGDFILNLAgdydfnTELSGNGALVKDNSGVMSYEGTLTQARGVNVKNGGIILGSAVVNADMAVSQNAYINISDq 787
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 356 VFIN---NIKGHLAIDasNSKITGSANLSTDDSTHTYLSLSdnstwdiktdSTVSKLTVDNSTVYISRADGKAfePTRLT 432
Cdd:NF033176 788 ATINgsvNNKGSVVIN--NSIINGNITNDADLSFGTAKLLS----------ATVNGSLVNNKNIILNPTKESA--GNTLT 853
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 433 ITeNYVGNNG-ILHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEFIKDSRIFAGA 511
Cdd:NF033176 854 VS-NYTGTPGsVISLGGVLEGDNSLTDRLVVKGNTSGQSDIVYVNEGGSGGQTIEGINIISVEGNSDAEFSLKNRVVAGA 932
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 512 YEYSLTRGNTEAT-NKNWYLTNFQATSGgetnsggssaptvapTPVLRPEAGSYVANLAAANTLFVMRLNDRAGETRYID 590
Cdd:NF033176 933 YDYTLQKGNVSGTdKKGWYLTSHLPTSD---------------TRQYRPENGSYATNMALANSLFLMDLNERKQFSAVND 997
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 591 pvTEQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGGFTDSDSWRLGVMAGYARDYNSTHSSVSDYRSK 670
Cdd:NF033176 998 --NTQPESASVWMKITGGRTSGKLSDGQNKTTTNQFINQLGGDIYKYHAEKLGDFTLGIMGGYANAKGKTINHTSKKGAR 1075
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 671 GSVRGYSAGLYATWFADDISKKGAYIDAWAQYSWFKNSVKGDELAYESYSAKGATVSLEAGYGFALNKSFGLEAAKYTWI 750
Cdd:NF033176 1076 NTLDGYSAGLYGTWYQNGANATGLFAETWMQYNWFNASVKGDGLEEEKYNLNGLTASVGGGYNLNVHTWTSPEGIKGEFW 1155
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 751 FQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLGFRTFIRTQEKNSGPHGDDFEPFVEMNWIHNSKDFAVSMNGVK 830
Cdd:NF033176 1156 LQPHLQAVWMGVTPDTHQEDNGTVVQGTGKNNLQTKAGIRASWKVKSSLDKDTGREFRPYIEANWIHNTHEFGVKMSGDN 1235
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 446691189 831 VEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF 882
Cdd:NF033176 1236 QLLSGSRNQGEIKTGIEGVITQNLSVNGGVAYQAGGHGSNAISGALGIKYSF 1287
|
|
| PL2_Passenger_AT |
cd01344 |
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of ... |
342-537 |
6.03e-49 |
|
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43, AIDA-1 and IcsA, as well as, the less characterized ShdA, MisL, and BapA autotransporters.
Pssm-ID: 238654 [Multi-domain] Cd Length: 188 Bit Score: 171.33 E-value: 6.03e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 342 NVTITDSEVSSAADVFINNikGHLAIDASNSkITGSANLSTDDSthtyLSLSDNSTWDIKTDSTVSKLTVDNSTVYISRA 421
Cdd:cd01344 1 GTITGNGGWKLGGDLTLGG--GALTLTTSLT-LTGTLLTGGAGT----LTLDSTSTWNITGTSTLNVGNLTNAGTIDLGN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 422 DGKAFepTRLTITENYVGNNGILHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEG-ESNGE 500
Cdd:cd01344 74 GSPAG--GTLTITGNYTGNGGTLRLNTVLGDDDSPTDRLVIDGDASGTTRVAVNNAGGSGATTGNGIEVVEVGGtSSNGA 151
|
170 180 190
....*....|....*....|....*....|....*..
gi 446691189 501 FIKDSRIFAGAYEYSLTRGNTEATNKNWYLTNFQATS 537
Cdd:cd01344 152 FSLAGRVVAGAYEYRLYRGGVSGNDGNWYLRSELAPP 188
|
|
| Autotransporter |
pfam03797 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
601-861 |
4.06e-35 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
Pssm-ID: 461054 [Multi-domain] Cd Length: 255 Bit Score: 134.43 E-value: 4.06e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 601 LWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGgftdsDSWRLGVMAGYARdynsTHSSVSDYRSKGSVRGYSAGL 680
Cdd:pfam03797 1 VWARGFGGRGKQDGDGGAAGYDADTGGLQVGADYRLG-----DNLRLGVAFGYSR----SDADVDGRGGSGDSDSYSLGL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 681 YATWFADDiskkGAYIDAWAQYSWFKNSVK-------GDELAYESYSAKGATVSLEAGYGFALNKSFGLEaakytwifqP 753
Cdd:pfam03797 72 YGTYYGDG----GWYLDGGLGYGWHDNDTRrsvdlggFSETAKGDYDGNGFGASLEAGYRFALGGGWTLE---------P 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 754 QAQAIWMGVDHNAHTEANGS---RIENDANNNFQTRLGFRTFIRTQEKNSgphgdDFEPFVEMNWIHNSKDFAVSMNG-- 828
Cdd:pfam03797 139 FAGLAYVRLRLDGFTESGGAaalSVDSQSYDSLTGRLGLRLSYTFDLGGG-----TLTPYARLGWRHEFGDDDPVTTAaf 213
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 446691189 829 ---------VKVEQDGARNLGEIKLGVNGNLNPAASVWGNVG 861
Cdd:pfam03797 214 aglsgagsfTVAGADLARDSLELGAGLSAQLSDNLSLYANYD 255
|
|
| Autotransporter |
smart00869 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
608-871 |
3.46e-30 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain] Cd Length: 268 Bit Score: 120.37 E-value: 3.46e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 608 GHNAWRDSNGQLRTTSHRYVSQLGAELLtggFTDSDSWRLGVMAGYARDynSTHSSVSDYRSKGSVRGYSAGLYATWFAD 687
Cdd:smart00869 8 LRQDSSGSGGSAGFDYDSYGLQLGADYR---LSDNGNLSLGFAAGYGNS--KVDFSGNKGSGKGDVDSYGLGLYAGYSLG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 688 DiskkGAYIDAWAQYSWFKNSVK------GDELAYESYSAKGATVSLEAGYGFALNKSfgleaakytWIFQPQAQAIWMG 761
Cdd:smart00869 83 N----GLYLDAQLGYGRSDNDTKrkvtlgGAGRAKGSYDGTGYGASLEAGYRFYLGGG---------LTLTPFAGLAYSR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 762 VDHNAHTEANGS----RIENDANNNFQTRLGFRTFIRTQEKNsgphGDDFEPFVEMNWIHNSKD---------FAVSMNG 828
Cdd:smart00869 150 VRQDGFTESGGGafglSVDSQSLDSLSLPLGLRLEYRLALGD----GATLTPYLRLAYVHDFYDdnpvvtaslLGSGASF 225
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 446691189 829 VKVEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYND 871
Cdd:smart00869 226 TTSGTDLDRNAAELGLGLSAKLSNGLSLSLNYDGEFGGSSRSH 268
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15313 |
PRK15313 |
intestinal colonization autotransporter adhesin MisL; |
109-882 |
3.06e-127 |
|
intestinal colonization autotransporter adhesin MisL;
Pssm-ID: 237940 [Multi-domain] Cd Length: 955 Bit Score: 406.49 E-value: 3.06e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 109 ILQGNNT-IVTTGDYSIGLLSQTNGNLntdtiIRVNTDGSVNphlsdegntfivTAGNHAVGVLACASpgsaracvssld 187
Cdd:PRK15313 219 IVVGNRAhIVTTGDSSEGLRTGQSGSL-----IRLGDDATIE------------TSGASSTGIYAASS------------ 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 188 eeSTADTGSNennakakldmakGEITTHGTESYAAYANGTVVKAGSkldytNASVTltdvdITTHGDNAHAIAARQGTVS 267
Cdd:PRK15313 270 --SRTELGNN------------ATITVNGASAHAVYATNATVNLGE-----NATIS-----VNSASKAASYSKAPAGLYA 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 268 FNQGEIHTTGPDAAIAKIYNGGKvtlknTSAVAHQGAGIVlESSINGQEATVDILSGSSLRSANEILYNKNETSNVTITD 347
Cdd:PRK15313 326 LSRGAINLAGGAAITMAGDNSSE-----SYAISTETGGIV-DGSSGGRFVIDGDIRAAGATAASGTLPQQNSTIKLNMTD 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 348 sevssaadvfinnikghlaidasNSKITGSANLSTDDSTHTYLSLS-DNSTWDIKTDSTVSKLTVDN-STVYISRADGKA 425
Cdd:PRK15313 400 -----------------------NSRWDGASYITSATAGTGVISVQmSDATWNMTSSSTLTDLTLNSgATINFSHEDGEP 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 426 FEPtrLTITENYVGNNGILHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEFIKDS 505
Cdd:PRK15313 457 WQT--LTINEDYVGNGGKLVFNTVLNDDDSETDRLQVLGNTSGNTFVAVNNIGGAGAQTIEGIEIVNVAGNSNGTFEKAS 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 506 RIFAGAYEYsltrgNTEATNKNWYLTNFqaTSGGETNSGGSSAPT----VAPTPV------------------------- 556
Cdd:PRK15313 535 RIVAGAYDY-----NVVQKGKNWYLTSY--IEPDEPIIPDPVDPVipdpVIPDPVdpdpvdpvipdpvipdpvdpdpvdp 607
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 557 ---------------------------LRPEAGSYVANLAAANTLFVMRLNDRAGETRYIDPVTEQERSSRLWLRQIGGH 609
Cdd:PRK15313 608 epvdpvipdptipdigqsdtppitehqFRPEVGSYLANNYAANTLFMTRLHDRLGETQYTDMLTGEKKVTSLWMRNVGAH 687
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 610 NAWRDSNGQLRTTSHRYVSQLGAELLTGGFTDSDSWRLGVMAGYARDYNSTHSSVSDYRSKGSVRGYSAGLYATWFADDI 689
Cdd:PRK15313 688 TRFNDGSGQLKTRINSYVLQLGGDLAQWSTDGLDRWHIGAMAGYANSQNRTLSSVSDYHSRGQVTGYSVGLYGTWYANNI 767
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 690 SKKGAYIDAWAQYSWFKNSVKGDELAYESYSAKGATVSLEAGYGFALNksfglEAAKYTWIFQPQAQAIWMGVDHNAHTE 769
Cdd:PRK15313 768 DRSGAYVDTWMLYNWFDNKVMGQDQAAEKYKSKGITASVEAGYSFRLG-----ESAHQSYWLQPKAQVVWMGVQADDNRE 842
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 770 ANGSRIENDANNNFQTRLGFRTFIRTQEKNSGPHGDDFEPFVEMNWIHNSKDFAVSMNGVKVEQDGARNLGEIKLGVNGN 849
Cdd:PRK15313 843 ANGTLVKDDTAGNLLTRMGVKAYINGHNAIDDNKSREFQPFVEANWIHNTQPASVKMDDVSSDMRGTKNIGELKVGIEGQ 922
|
810 820 830
....*....|....*....|....*....|...
gi 446691189 850 LNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF 882
Cdd:PRK15313 923 ITPRLNVWGNVAQQVGDQGYSNTQGLLGVKYSF 955
|
|
| AidA |
COG3468 |
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ... |
35-882 |
1.51e-124 |
|
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain] Cd Length: 846 Bit Score: 396.24 E-value: 1.51e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 35 AVAIKDGEVKDIDNALVITTGNGSYGVSVAGEGSNLTINKGVIVTTGGLYPSGNSPLSTVYTASAVVSEYGGAVILQGNN 114
Cdd:COG3468 28 GGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAGSGGTGGNSTGGGGGNSGTGGTGGGGGG 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 115 TIVTTGDYSIGLLSQTNGN-LNTDTIIRVNTDGSVNPHLSDEGNTFIVTAGNHAVGVLACASPGSARACVSSLDEESTAD 193
Cdd:COG3468 108 GGSGNGGGGGGGGGGGGTGgGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGTGSGGGGSGGGGGAGGGGGGGAGGSGG 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 194 TGSNENNAKAKLDMAKGEITTHGTESYAAYANGTVVKAGSKLDYTNASVTLTDVDITTHGDNAHAIAARQGTVSFNQGEI 273
Cdd:COG3468 188 AGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGGGGSAGGTGGGGLTGGGAAGTGGGGGG 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 274 HTTGPDAAIAKIYNGGKVTLKNTSAVAhqGAGIVLESSINGQEATVDILSGSSLRSANEILYNKNETSNVTITDSEVSSA 353
Cdd:COG3468 268 TGTGSGGGGGGGANGGGSGGGGGASGT--GGGGTASTGGGGGGGGGNGGGGGGGSNAGGGSGGGGGGGGGGGGGGTTLNG 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 354 ADVFINNIKGHLAIDASNSKITGSANLSTDDSTHTYLSLSDNSTWDIKTDSTVSKLTVDNSTVYISRADGKAFEPTRLTI 433
Cdd:COG3468 346 AGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGTGNNGGGGVGGGGGGGLTLTGGTLTV 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 434 TENYVGNNGILHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEFIKDSRIFAGAYE 513
Cdd:COG3468 426 NGNYTGNNGTLVLNTVLGDDNSPTDRLVVNGNTSGTTGVRVNNAGGLGAQTVNGIEVVEVNGASDGAFTLGGRVVAGAYE 505
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 514 YSLTRGNTEATNKNWYLTNfqatsggetnsggSSAPTVAPTPVLRPEAGSYVANLAAANTLFVM-RLNDRAGETRYIDpv 592
Cdd:COG3468 506 YTLYQGGSGGDDGNWYLRS-------------TLTPPDPPTPVYRPEVPSYLANPAAANGLFELgTLHDRLGERRYTD-- 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 593 TEQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGGfTDSDSWRLGVMAGYARDYNSTHSSVSdYRSKGS 672
Cdd:COG3468 571 TGESDNSGAWLRVEGGHNRSRDSSGQLDYDSNRYGLQLGGDLLQWE-DGGGRLHVGVMAGYGNGDSDVRSRAT-GTGKGD 648
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 673 VRGYSAGLYATWFADDiskkGAYIDAWAQYSWFKNSVKGDELAY--ESYSAKGATVSLEAGYGFALNKSfgleaakytWI 750
Cdd:COG3468 649 VDGYSLGLYGTWYGNN----GFYVDGVLQYSWFDNDVSSDDLGGvtGSYDGNGYSASLEAGYPFKLGEG---------WS 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 751 FQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLGFRTFIRTQEKNSGPhgddFEPFVEMNWIHN-SKDFAVSMNGV 829
Cdd:COG3468 716 LEPQAQLIYQGVDFDDFTDSNGTRVSGDDGDSLQGRLGLRLGYEFHWDDGRA----LQPYLEANWLHEfLGDNSVTVNGV 791
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*
gi 446691189 830 KVEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYN--DTAVMVGLKYKF 882
Cdd:COG3468 792 SFSQDGSGTWGELGLGVTGQLNKNLSLYGDVGYQTGLDGYDssDTSGNLGVRYSF 846
|
|
| PRK14849 |
PRK14849 |
autotransporter barrel domain-containing lipoprotein; |
431-882 |
3.13e-117 |
|
autotransporter barrel domain-containing lipoprotein;
Pssm-ID: 184851 [Multi-domain] Cd Length: 1806 Bit Score: 392.95 E-value: 3.13e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 431 LTITENYVGNNGILHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEF-IKDSRIFA 509
Cdd:PRK14849 1352 LTVNGNYTGNNGLMTFNATLGGDNSPTDKMNVKGDTQGNTRVRVDNIGGVGAQTVNGIELIEVGGNSAGNFaLTTGTVEA 1431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 510 GAYEYSLTRGNTEaTNKNWYLTN-FQATSGGETNSGGSSAPTVAPT--PVLRPEAGSYVANLAAANTLFVMRLNDRAGET 586
Cdd:PRK14849 1432 GAYVYTLAKGKGN-DEKNWYLTSkWDGVTPPDTPDPINNPPVVDPEgpSVYRPEAGSYISNIAAANSLFSHRLHDRLGEP 1510
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 587 RYIDPVTEQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGGFTDSDSWRLGVMAGYARDYNSTHSSVSD 666
Cdd:PRK14849 1511 QYIDSLHSQGSASSMWMRHVGGHERSRAGDGQLNTQANRYVLQLGGDLAQWSSNAQDRWHLGVMAGYANQHSNTQSNRVG 1590
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 667 YRSKGSVRGYSAGLYATWFADDISKKGAYIDAWAQYSWFKNSVKGDELAYESYSAKGATVSLEAGYGFALNKSFGLEAAK 746
Cdd:PRK14849 1591 YKSDGRISGYSAGLYATWYQNDANKTGAYVDSWALYNWFDNSVSSDNRSADDYDSRGVTASVEGGYTFEAGTFSGSEGTL 1670
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 747 YTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLGFRTFIRTQEKNSGPHGDDFEPFVEMNWIHNSKDFAVSM 826
Cdd:PRK14849 1671 NTWYVQPQAQITWMGVKDSDHTRKDGTRIETEGDGNVQTRLGVKTYLNSHHQRDDGKQREFQPYIEANWINNSKVYAVKM 1750
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 446691189 827 NGVKVEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF 882
Cdd:PRK14849 1751 NGQTVGREGARNLGEVRTGVEAKVNNNLSLWGNVGVQLGDKGYSDTQGMLGVKYSW 1806
|
|
| autotrans_barl |
TIGR01414 |
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ... |
430-882 |
1.59e-96 |
|
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain] Cd Length: 431 Bit Score: 309.31 E-value: 1.59e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 430 RLTITENYVGNNGIlHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEF-IKDSRIF 508
Cdd:TIGR01414 7 TLTVNGLYTGNGGF-VMNTDLGGDNSQTDRLVVNGNASGTTGVVVNNIGGEGAQTGDGITLVTVNGGSDAAFtLANGKVD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 509 AGAYEYSLTRGNTEATNkNWYLTnfqatsggeTNSGGSSAPTVAPTPVLRPEAGSYVANLAAANTLF-VMRLNDRAGETR 587
Cdd:TIGR01414 86 AGAYTYTLYKNGTEDNN-NWYLT---------SSLPDLTPPGQQLSPTYRAEAGSYAANANAALFLAeLDTLRQRMGDLR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 588 YIDpvteQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGGFTDSDsWRLGVMAGYARdyNSTHSSVSDY 667
Cdd:TIGR01414 156 SAA----RDAGNGVWARIFGGDNHLDGDAGAAGYDQNTTGVQLGGDILLAGNADGD-LHVGLMAGYAK--ADIKTRSYKY 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 668 RSKGSVRGYSAGLYATWFADDiskkGAYIDAWAQYSWFKNSVKGDEL---AYESYSAKGATVSLEAGYGFALnksfglea 744
Cdd:TIGR01414 229 GGKGKVDGYGLGLYGTWLQDS----GAYVDGVLQYSRFRNDVSSTGSngkVSGKYNSNGFTASLEAGYRYNL-------- 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 745 AKYTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLGFRtFIRTQEKNSgphGDDFEPFVEMNWIHNSKD-FA 823
Cdd:TIGR01414 297 GGNGWYVEPQAQLSYFGVSGDDYKESNGTRVLGGGGDSLQGRLGLR-VGYQFDLGT---GRAVKPYLKANVLHEFKGgTG 372
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 446691189 824 VSMNGVKVEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF 882
Cdd:TIGR01414 373 VRVNGVTIRNDFSGTRAEYGVGVNAKIKDNLSLYADVDYQKGGKKYTDNQGNLGVRYSF 431
|
|
| auto_AIDA-I |
NF033176 |
autotransporter adhesin AIDA-I; |
213-882 |
2.89e-78 |
|
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain] Cd Length: 1287 Bit Score: 277.31 E-value: 2.89e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 213 TTHGTESYAAY------ANGTVVKAGSKLDYTNASvTLTDVDITTHG----DNAHAIaarQGTVSFNQGEIhttgpdAAI 282
Cdd:NF033176 638 TVTGTNHYGSFsvsqnhASNVVLENGGLLAVTSGS-TATDTTVNSAGrlriDEGGAL---DGTTTINADGI------VAG 707
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 283 AKIYNGGKVTLKNT------SAVAHQGAGIVLESSINGQEATVDILSGSSLRSANEILYNKNETSNVTITDSEVSSAAD- 355
Cdd:NF033176 708 AKIKNDGDFILNLAgdydfnTELSGNGALVKDNSGVMSYEGTLTQARGVNVKNGGIILGSAVVNADMAVSQNAYINISDq 787
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 356 VFIN---NIKGHLAIDasNSKITGSANLSTDDSTHTYLSLSdnstwdiktdSTVSKLTVDNSTVYISRADGKAfePTRLT 432
Cdd:NF033176 788 ATINgsvNNKGSVVIN--NSIINGNITNDADLSFGTAKLLS----------ATVNGSLVNNKNIILNPTKESA--GNTLT 853
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 433 ITeNYVGNNG-ILHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEFIKDSRIFAGA 511
Cdd:NF033176 854 VS-NYTGTPGsVISLGGVLEGDNSLTDRLVVKGNTSGQSDIVYVNEGGSGGQTIEGINIISVEGNSDAEFSLKNRVVAGA 932
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 512 YEYSLTRGNTEAT-NKNWYLTNFQATSGgetnsggssaptvapTPVLRPEAGSYVANLAAANTLFVMRLNDRAGETRYID 590
Cdd:NF033176 933 YDYTLQKGNVSGTdKKGWYLTSHLPTSD---------------TRQYRPENGSYATNMALANSLFLMDLNERKQFSAVND 997
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 591 pvTEQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGGFTDSDSWRLGVMAGYARDYNSTHSSVSDYRSK 670
Cdd:NF033176 998 --NTQPESASVWMKITGGRTSGKLSDGQNKTTTNQFINQLGGDIYKYHAEKLGDFTLGIMGGYANAKGKTINHTSKKGAR 1075
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 671 GSVRGYSAGLYATWFADDISKKGAYIDAWAQYSWFKNSVKGDELAYESYSAKGATVSLEAGYGFALNKSFGLEAAKYTWI 750
Cdd:NF033176 1076 NTLDGYSAGLYGTWYQNGANATGLFAETWMQYNWFNASVKGDGLEEEKYNLNGLTASVGGGYNLNVHTWTSPEGIKGEFW 1155
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 751 FQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLGFRTFIRTQEKNSGPHGDDFEPFVEMNWIHNSKDFAVSMNGVK 830
Cdd:NF033176 1156 LQPHLQAVWMGVTPDTHQEDNGTVVQGTGKNNLQTKAGIRASWKVKSSLDKDTGREFRPYIEANWIHNTHEFGVKMSGDN 1235
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 446691189 831 VEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF 882
Cdd:NF033176 1236 QLLSGSRNQGEIKTGIEGVITQNLSVNGGVAYQAGGHGSNAISGALGIKYSF 1287
|
|
| PRK09752 |
PRK09752 |
AIDA-I family autotransporter YfaL; |
45-882 |
2.79e-53 |
|
AIDA-I family autotransporter YfaL;
Pssm-ID: 182059 [Multi-domain] Cd Length: 1250 Bit Score: 201.83 E-value: 2.79e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 45 DIDNALVITTGNGSYGVSVAGEGSNLTINKGVIVTTGglypsgnspLSTVYTASAVVSEYGGAVILQGNNTIVTTGDYSI 124
Cdd:PRK09752 418 NIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAG---------AQSMALTGDIVVDDGAVLSLEGDAADLRALQDDP 488
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 125 GLLSQTNGNLNTDTIIRVNTDGSVNPHLSDEGNTFIVTAGNHAVGvlacaspgsaracVSSLDEESTAdtGSNENNAKAK 204
Cdd:PRK09752 489 QSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVD-------------LAGGDDLHIG--GDGKDGVYVV 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 205 LDMAKGEITTHGTESY---AAYANGTV-VKAGSKLDYT--NASVTLTD------VDITTHGDNAHAIAARQGTVSFN-QG 271
Cdd:PRK09752 554 IDAGDGQVSLANNNSYlgtTQIASGTLmVSDNSQLGDThyNRQVIFTDkqqesvMEITADVDTRSTTTGHGRDIEMRaDG 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 272 EIHT-TGPDA---------------AIAKIYNGGKVTLKNTSAVAHQGAGIVLESSINGQEATVdILSGSSL-------- 327
Cdd:PRK09752 634 EVAVdAGVDTqwgalmadssgqhqdEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADI-IPYASSLwvgdgatf 712
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 328 -RSANEILYNKNETSNVTI----------TDSEVSSAADVFINNIKGHLAIDASNSKITGSANLSTDDSTHTYLSlsdns 396
Cdd:PRK09752 713 vTGADQDIQSIDATSSGTIdisdgtvlrlTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLS----- 787
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 397 twdiktDSTVSKlTVDNSTVYISRADGKAFEPtrLTITENYVGnNGILHLRTELGDDNSATDKVVINGNTSGTTRVKVTN 476
Cdd:PRK09752 788 ------DVTVNG-NLTNTSGAVSLQNGVAGDT--LTVNGDYTG-GGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNS 857
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 477 AGGSGAYTLNGIEIIS-----VEGESNGEF--IKDSRIFAGAYEYSLTRGNTEatnknWYLTNFQATSGG---------- 539
Cdd:PRK09752 858 ITGIGEPTSTGIKVVDfaadpTQFQNNAQFslAGSGYVNMGAYDYTLVEDNND-----WYLRSQEVTPPSppdpdptpdp 932
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 540 ----ETNSGGSSAPTVAPTPVLRPEAGSYVANLAAANTLFVMRLNDRAGETryidpvteqerSSRLWLRQIGGHNAWrDS 615
Cdd:PRK09752 933 dptpDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGD-----------GQTLNLRVIGGDYHY-TA 1000
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 616 NGQLRTTSHRYVSQLGAELLTGGFTDSDSWRLGVMAGYARDYNSTHSSVSDYRSKGSVRGYSAGLYATWFADDISKKGAY 695
Cdd:PRK09752 1001 AGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGIVGGYSDNQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAW 1080
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 696 IDAWAQYSWFKNSVKGDELAYESYSAKGATVSLEAGYGFALNKSFgleaakytwIFQPQAQAIWMGVDHNAHTEANGSRI 775
Cdd:PRK09752 1081 LDSWLQYAWFNNDVSEQEDGTDHYHSSGIIASLEAGYQWLPGRGV---------VIEPQAQVIYQGVQQDDFTAANHARV 1151
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 776 ENDANNNFQTRLGFRTFIRTqeknsgphGDDFEPFVEMNWIHNSKDFAVSMNGVKVEQDGARNLGEIKLGVNGNLNPAAS 855
Cdd:PRK09752 1152 SQSQGDDIQTRLGLHSEWRT--------AVHVIPTLDLNYYHDPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVS 1223
|
890 900
....*....|....*....|....*..
gi 446691189 856 VWGNVGVQLGDNGYNDTAVMVGLKYKF 882
Cdd:PRK09752 1224 LRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
|
|
| PL2_Passenger_AT |
cd01344 |
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of ... |
342-537 |
6.03e-49 |
|
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43, AIDA-1 and IcsA, as well as, the less characterized ShdA, MisL, and BapA autotransporters.
Pssm-ID: 238654 [Multi-domain] Cd Length: 188 Bit Score: 171.33 E-value: 6.03e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 342 NVTITDSEVSSAADVFINNikGHLAIDASNSkITGSANLSTDDSthtyLSLSDNSTWDIKTDSTVSKLTVDNSTVYISRA 421
Cdd:cd01344 1 GTITGNGGWKLGGDLTLGG--GALTLTTSLT-LTGTLLTGGAGT----LTLDSTSTWNITGTSTLNVGNLTNAGTIDLGN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 422 DGKAFepTRLTITENYVGNNGILHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEG-ESNGE 500
Cdd:cd01344 74 GSPAG--GTLTITGNYTGNGGTLRLNTVLGDDDSPTDRLVIDGDASGTTRVAVNNAGGSGATTGNGIEVVEVGGtSSNGA 151
|
170 180 190
....*....|....*....|....*....|....*..
gi 446691189 501 FIKDSRIFAGAYEYSLTRGNTEATNKNWYLTNFQATS 537
Cdd:cd01344 152 FSLAGRVVAGAYEYRLYRGGVSGNDGNWYLRSELAPP 188
|
|
| PRK15319 |
PRK15319 |
fibronectin-binding autotransporter adhesin ShdA; |
431-882 |
2.14e-48 |
|
fibronectin-binding autotransporter adhesin ShdA;
Pssm-ID: 185219 [Multi-domain] Cd Length: 2039 Bit Score: 187.21 E-value: 2.14e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 431 LTITENYVGNNGILHLRTELGDDNSATDKVVINGNTSGTTRVKVtNAGGSGAYTLNGIEIISVEGESNGE-FIKDSRIFA 509
Cdd:PRK15319 1567 LYVDGNYTGNGGSLYLNTVLGDDDSATDKLVITGDASGTTDLYI-NGIGDGAQTTNGIEVVDVGGVSTSDaFELKNEVNA 1645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 510 GAYEYSLTRGNTEatnKNWYLTNFQAT----SGGET--NSGGSSAPTVAP------------------------------ 553
Cdd:PRK15319 1646 GLYTYRLYWNESD---NDWYLASKAQSddddSGGDDtpSDGGDDGGNVTPpddggdggnvtppddggdggdvtppdhggd 1722
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 554 -TPVLRPEAGSYVANLAAANTLFVMRLNDRAGeTRYidpvteQERSSRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGA 632
Cdd:PRK15319 1723 vAPQYRADIGAYMGNQWMARNLQMQTLYDREG-SQY------RNADGSVWARFKAGKAESEAVSGNIDMDSNYSQFQLGG 1795
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 633 ELLTGGfTDSDSWRLGVMAGYAR-DYNSTHSSVSD---YRSKGSVRGYSAGLYATWFADDISKKGAYIDAWAQYSWFKNS 708
Cdd:PRK15319 1796 DILAWG-NGQQSVTVGVMASYINaDTDSTGNRGADgsqFTSSGNVDGYNLGVYATWFADAQTHSGAYVDSWYQYGFYNNS 1874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 709 VKGDELAYESYSAKGATVSLEAGYGFALNKSFGleaakYTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLG 788
Cdd:PRK15319 1875 VESGDAGSESYDSTANAVSLETGYRYDIALSNG-----NTVSLTPQAQVVWQNYSADSVKDNYGTRIDGQDGDSWTTRLG 1949
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 789 frtfIRTQEKNSGPHGDDFEPFVEMNWIHNSKDFAVSMNGVKVEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNG 868
Cdd:PRK15319 1950 ----LRVDGKLYKGSRTVIQPFAEANWLHTSDDVSVSFDDATVKQDLPANRAELKVGLQADIDKQWSVRAQVAGQTGSND 2025
|
490
....*....|....
gi 446691189 869 YNDTAVMVGLKYKF 882
Cdd:PRK15319 2026 FGDLNGSLNLRYNW 2039
|
|
| PL_Passenger_AT |
cd00253 |
Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V ... |
375-537 |
8.61e-38 |
|
Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain of autotransporters forms a pore in the outer membrane through which the N-terminal passenger domain is transported. Following transport, the passenger domain is generally cleaved by an outer membrane protease with the passenger domain either remaining in contact with the surface via a noncovalent interaction with the beta domain or cleaved to release a soluble protein. These proteins are highly diverse and perform a variety of functions that promote virulence, including catalyzing proteolysis, serving as an adhesin, mediating actin-promoted motility, or serving as a cytotoxin. Proteins in this family share similarity in the C-terminal region of the passenger domain as seen in the pertactin structure P.69, a Bordetella pertussis agglutinogen responsible for human pertussis. The P.69 protein consists of a 16-stranded parallel beta-helix with a V-shaped cross-section, and is one of the largest beta-helix known to date.
Pssm-ID: 238156 [Multi-domain] Cd Length: 186 Bit Score: 139.81 E-value: 8.61e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 375 TGSANLSTDDSTHTYLSLSDNSTWDIKTDSTVS-KLTVDNSTVYISRADGKAfepTRLTITENYVGNNGILHLRTELGDD 453
Cdd:cd00253 27 GNSVWLGTLQAGGGTVSLNSNSLWTLTGDSTVNgNLTNSGGTVDFGSASGAF---NTLTVNGNYLGGNGTFVLNTDLGGD 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 454 NSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEFIKDSRIFAGAYEYSLTRGnTEATNKNWYLTNF 533
Cdd:cd00253 104 NSPTDKLVVTGNASGTTNVAVVNAGGEGASTGDGIELVEVNGGSDAAFSLAGRVDAGAYEYTLYKG-GVGNNGNWYLRST 182
|
....
gi 446691189 534 QATS 537
Cdd:cd00253 183 LAPP 186
|
|
| Autotransporter |
pfam03797 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
601-861 |
4.06e-35 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
Pssm-ID: 461054 [Multi-domain] Cd Length: 255 Bit Score: 134.43 E-value: 4.06e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 601 LWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGgftdsDSWRLGVMAGYARdynsTHSSVSDYRSKGSVRGYSAGL 680
Cdd:pfam03797 1 VWARGFGGRGKQDGDGGAAGYDADTGGLQVGADYRLG-----DNLRLGVAFGYSR----SDADVDGRGGSGDSDSYSLGL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 681 YATWFADDiskkGAYIDAWAQYSWFKNSVK-------GDELAYESYSAKGATVSLEAGYGFALNKSFGLEaakytwifqP 753
Cdd:pfam03797 72 YGTYYGDG----GWYLDGGLGYGWHDNDTRrsvdlggFSETAKGDYDGNGFGASLEAGYRFALGGGWTLE---------P 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 754 QAQAIWMGVDHNAHTEANGS---RIENDANNNFQTRLGFRTFIRTQEKNSgphgdDFEPFVEMNWIHNSKDFAVSMNG-- 828
Cdd:pfam03797 139 FAGLAYVRLRLDGFTESGGAaalSVDSQSYDSLTGRLGLRLSYTFDLGGG-----TLTPYARLGWRHEFGDDDPVTTAaf 213
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 446691189 829 ---------VKVEQDGARNLGEIKLGVNGNLNPAASVWGNVG 861
Cdd:pfam03797 214 aglsgagsfTVAGADLARDSLELGAGLSAQLSDNLSLYANYD 255
|
|
| Autotransporter |
smart00869 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
608-871 |
3.46e-30 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain] Cd Length: 268 Bit Score: 120.37 E-value: 3.46e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 608 GHNAWRDSNGQLRTTSHRYVSQLGAELLtggFTDSDSWRLGVMAGYARDynSTHSSVSDYRSKGSVRGYSAGLYATWFAD 687
Cdd:smart00869 8 LRQDSSGSGGSAGFDYDSYGLQLGADYR---LSDNGNLSLGFAAGYGNS--KVDFSGNKGSGKGDVDSYGLGLYAGYSLG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 688 DiskkGAYIDAWAQYSWFKNSVK------GDELAYESYSAKGATVSLEAGYGFALNKSfgleaakytWIFQPQAQAIWMG 761
Cdd:smart00869 83 N----GLYLDAQLGYGRSDNDTKrkvtlgGAGRAKGSYDGTGYGASLEAGYRFYLGGG---------LTLTPFAGLAYSR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 762 VDHNAHTEANGS----RIENDANNNFQTRLGFRTFIRTQEKNsgphGDDFEPFVEMNWIHNSKD---------FAVSMNG 828
Cdd:smart00869 150 VRQDGFTESGGGafglSVDSQSLDSLSLPLGLRLEYRLALGD----GATLTPYLRLAYVHDFYDdnpvvtaslLGSGASF 225
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 446691189 829 VKVEQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYND 871
Cdd:smart00869 226 TTSGTDLDRNAAELGLGLSAKLSNGLSLSLNYDGEFGGSSRSH 268
|
|
| AC_1 |
pfam18883 |
Autochaperone Domain Type 1; This entry represents the autochaperone domain of type 1 (AC-1) ... |
404-516 |
1.81e-27 |
|
Autochaperone Domain Type 1; This entry represents the autochaperone domain of type 1 (AC-1) in the Type Va Secretion System (T5aSS). Autotransporters (ATs) belong to a family of modular proteins secreted by the Type V, subtype a, secretion system (T5aSS) and considered as an important source of virulence factors in lipopolysaccharidic diderm bacteria (archetypical Gram-negative bacteria). The AC of type 1 with beta-fold appears as a prevalent and conserved structural element exclusively associated to beta-helical AT passenger.
Pssm-ID: 465898 [Multi-domain] Cd Length: 114 Bit Score: 107.31 E-value: 1.81e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 404 STVSKLTVDNSTVYISRADGKAFepTRLTITENYVGNNGILHLRTELGDDNSATDKVVINGNT-SGTTRVKVTNAGGSGA 482
Cdd:pfam18883 1 SNVTNLTNDNSTINFTAPSGASY--KTLTVDGDYTGNDGTLALNTYLGGDGSPSDKLVIDGGTaSGTTNLRINNTGGPGA 78
|
90 100 110
....*....|....*....|....*....|....*.
gi 446691189 483 YT-LNGIEIISVEG-ESNGEFIKDSRIFAGAYEYSL 516
Cdd:pfam18883 79 LTtNDGILVVDVGGtTSDGAFRLAGRAVAGPYEYLL 114
|
|
| YhjY |
COG5571 |
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ... |
454-882 |
3.25e-12 |
|
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];
Pssm-ID: 444313 [Multi-domain] Cd Length: 648 Bit Score: 70.29 E-value: 3.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 454 NSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGI--EIISVEGESNGEFIKDSRIFAGAYEYSLTRGNTEATNKNWYLT 531
Cdd:COG5571 210 AAAAAAAAAAVLASPAPAAGGAAAAAAGAAAAAASaaANAATQANLLLLALALGSNGNAVGLNAVGLANEAAAPGAVGGD 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 532 NFQATSGGETNSGGSSAPTVAPTPVLRP----------------EAGSYVANLAAANTLFVMRLNDRAGETRYIDPVTEq 595
Cdd:COG5571 290 AGSTGATPSTLSSASCVASSLTAANANTlyaaadtagpagataaLAAAAAAVLASAAAVAQAALALAAAGGQARSLAVA- 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 596 eRSSRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGG-FTDSDSWRLGVMAGYARDynsthSSVSDYRSKGSVR 674
Cdd:COG5571 369 -AGQGRGARGGQTRGGGGAGGTTGGGVGAGGGDGDGPNLTLGVdYRLSDNLLLGAALSYGRQ-----DLDFGDGGSYDAR 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 675 GYSAGLYATWFADdiskkGAYIDAWAQYSWFKNSVK-----GDELAYES--YSAKGATVSLEAGYGFALNksfgleaaky 747
Cdd:COG5571 443 STSLSLYAGYRAG-----GLWVDADLSYGDLDYDIRrhirlGPATRTETgdTDGSQWGARLTAGYDFTAG---------- 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 748 TWIFQPQAQAIWMGVDHNAHTEANGS----RIENDANNNFQTRLGFRTfirtqeknSGPHGDDFEPFVEMNWIHNSKD-- 821
Cdd:COG5571 508 RLRTGPFAGLDYQKVKVDGYTETGAGstalSFGDQDRDSLVGSLGWRA--------DYQLLGRFNPYAEVAYEHEFGDdd 579
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446691189 822 --------------FAVSMngvkveQDGARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF 882
Cdd:COG5571 580 rdvtaglaslpagsFSLPA------AAPDKNWGRATLGASAALTNGVSLFAGYSGTFGRDDGRQTSVNLGLSARF 648
|
|
| COG4625 |
COG4625 |
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ... |
47-882 |
6.76e-12 |
|
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];
Pssm-ID: 443664 [Multi-domain] Cd Length: 900 Bit Score: 69.42 E-value: 6.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 47 DNALVITTGNGSYGVSVAGEGSNLTINKGVIVTTGGLYPSGNSPLSTVYTASAVVSEYGGAVILQGNNTIVTTGDYSIGL 126
Cdd:COG4625 40 GGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSA 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 127 LSQTNGNLNTDTIIRVNTDGSVNPHLSDEGNTFIVTAGNHAVGVLACASPGSARACVSSLDEESTADTGSNENNAKAKLD 206
Cdd:COG4625 120 GGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGG 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 207 MAKGEITTHGTESYAAYANGTVVKAGSKLDYTNASVTLTDVDITTHGDNAHAIAARQGTVSFNQGEIHTTGPDAAIAKIY 286
Cdd:COG4625 200 GGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGG 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 287 NGGKVTLKNTSAVAHQGAGIVLESSINGQEATVDILSGSSLRSANEILYNKNETSNVTITDSEVSSAADVFINNIKGHLA 366
Cdd:COG4625 280 GGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGG 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 367 IDASNSKITGSANLSTDDSTHTYLSLSDNSTWDIKTDSTVSKLTVDNSTVYISRADGKAFEPTRLTITENYVGNNGILHL 446
Cdd:COG4625 360 GGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTG 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 447 RTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNG----IEIISVEGESNGEFIKDSRIFAGAYEYSLTR---- 518
Cdd:COG4625 440 AGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGnntyTGTTTVNGGGNYTQSAGSTLAVEVDAANSDRlvvt 519
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 519 ------GNTEATNKNWYLTNFQATSGGETNSGGSSAPTVAPTPV------------------LRPEAGSYVANLAAANTL 574
Cdd:COG4625 520 gtatlnGGTVVVLAGGYAPGTTYTILAVAAALDALAGNGDLSALynalaaldaaaaraaldqLSGEIHASAAAALLQASR 599
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 575 FVMR-LNDRAGETRYIDPVTEQERS-SRLWLRQIGGHNAWRDSNGQLRTTSHRYVSQLGAELLTGgftdsDSWRLGVMAG 652
Cdd:COG4625 600 ALRDaLSNRLRALRGAGAAGDAAAEgWGVWAQGFGSWGDQDGDGGAAGYDSSTGGLLVGADYRLG-----DNWRLGVALG 674
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 653 YARdynsTHSSVSDYRSKGSVRGYSAGLYATWFADDIskkgaYIDAWAQYSWFKNSVK-------GDELAYESYSAKGAT 725
Cdd:COG4625 675 YSR----SDVDVDDRGSSGDSDSYHLGLYGGYQFGAL-----YLDGGLGYGWNDYDTDrtiafggLSRTATADYDGDTAS 745
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 726 VSLEAGYGFALNKsfgleaakytWIFQPQAQAIWMGVDHNAHTEANGS---RIENDANNNFQTRLGFRTFIRTQEKNsgp 802
Cdd:COG4625 746 AFLEAGYRFDLGG----------LTLTPFAGLAYVRLRTDGFTETGGAaalSVDSQSTDSLRSTLGLRASRTFSLGG--- 812
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 803 hGDDFEPFVEMNWIHNSKDFAVSMNGVKVEQDG----------ARNLGEIKLGVNGNLNPAASVWGNVGVQLGDNgYNDT 872
Cdd:COG4625 813 -GVTLTPSGRLGWRHEFGDDDPSTTASFAGAPGaaftvagaplARDALVLGAGLSARLSDGLSLGLGYDGEFGSG-YTDH 890
|
890
....*....|
gi 446691189 873 AVMVGLKYKF 882
Cdd:COG4625 891 GGSAGLRYRF 900
|
|
| PL1_Passenger_AT |
cd01343 |
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of ... |
303-537 |
1.01e-11 |
|
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases, SPATEs (serine protease autotransporters secreted by Enterobacteriaceae), Bordetella pertacins, and nonprotease autotransporters, TibA and similar AIDA-like proteins.
Pssm-ID: 238653 [Multi-domain] Cd Length: 233 Bit Score: 65.84 E-value: 1.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 303 GAGIVLESSINGQEATVDILSGSSLRSANEILYNKNETSNVTITDSEVSSAADVFINNIKGHLAIDAS-------NSKIT 375
Cdd:cd01343 1 GRLVSDGGNITAGDNAQLTLGGGALYGSSVTLTNGAVLDAGNANLSAAASYATLSGSNIRGTVVLGAGqplqalaELLLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 376 GSANLSTD-DSTHTYLSLSDNSTWDIKTDSTVSKLTVDNSTVYISRADGKAFEptrlTITENYVGNNGILHLRTELgdDN 454
Cdd:cd01343 81 GNAAWTGAiQGLNATVSLNLNSVWTLTGDSNVNNLTLNGGTVDFNGPSAGKFN----TLTVNTLSGNGTFVMRTDL--AG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 455 SATDKVVINGNTSGTTRVKVTNAGGSGAYTLNgIEIISVEGESNGEFIKDS-RIFAGAYEYSLTRgnteATNKNWYLTNF 533
Cdd:cd01343 155 GQGDKLVVTGSATGDFNLLVVNTGKEPTSGLN-LTLVSTPKGGDAEFTLANgTVDLGAYRYTLVK----DGNGNWTLTGP 229
|
....
gi 446691189 534 QATS 537
Cdd:cd01343 230 KKES 233
|
|
| Pertactin |
pfam03212 |
Pertactin; |
406-532 |
2.00e-04 |
|
Pertactin;
Pssm-ID: 460848 [Multi-domain] Cd Length: 121 Bit Score: 42.00 E-value: 2.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 406 VSKLTVDNSTVYISRADGKAFEPTRLTIteNYVGNNGILHLRTELgdDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTL 485
Cdd:pfam03212 1 VAALALSGGTVDFASPAEPAGAFKTLTT--QTLSGSGTFVMNADV--ASGTGDQLVVSGNASGQHVLLVRNTGSEPASGN 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 446691189 486 NGIEIISVEGeSNGEFI---KDSRIFAGAYEYSLtrgnTEATNKNWYLTN 532
Cdd:pfam03212 77 TKLTLVETGG-GDAAFTlgnKGGKVDAGTYRYRL----TADGNGNWSLTA 121
|
|
| PRK15319 |
PRK15319 |
fibronectin-binding autotransporter adhesin ShdA; |
240-477 |
1.91e-03 |
|
fibronectin-binding autotransporter adhesin ShdA;
Pssm-ID: 185219 [Multi-domain] Cd Length: 2039 Bit Score: 41.99 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 240 ASVTLTDVDITTHGDNAHAIAARQGTVSFNQGEIHTTGPDAAIAKIYNGGKVTLKNT--SAVAHQGAGIVLESSINGQEA 317
Cdd:PRK15319 144 AILELTDAKITTTGIYTQGISAADGSTLTLTDSTLTIDGNFGVMTLYTGSEATLDGTivEAANSSSAQVQQGSTLNVLDG 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 318 TVDILSGSSLRSANEILYNkNETSNVTITDSEVSSAADVFINNIKGHLAIDASNSKIT----GSANLSTDDSTHTYLSLS 393
Cdd:PRK15319 224 STITLAQGQINVVAGNTAT-DEGSTLNLSDSSVSSAGTMSTIQGTNKAALNLTNATIThtnaSGAAVQANNATTLDISGG 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 394 DNSTWDIKTDSTVSKLTVDNSTVyisRADGKAFEPTRLTITENYVGNNGilhLRTELGDDNSATDKVVINGNTSGTTRVK 473
Cdd:PRK15319 303 NITSAGTGVYILASDARIDGATI---NADGDGIFITSKRKLTGYEDLNA---LTVSDANVTSDTVALHVDGSTTINDPIE 376
|
....
gi 446691189 474 VTNA 477
Cdd:PRK15319 377 LTDS 380
|
|
| FhaB |
COG3210 |
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ... |
54-548 |
1.97e-03 |
|
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain] Cd Length: 1698 Bit Score: 42.06 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 54 TGNGSYGVSVAGEGSNLTINK---GVIVTTGGLYPSGNSPLSTVYTASAVVSEYGGAVILQGNNTIVTTGDYSIGLLSQT 130
Cdd:COG3210 805 TAAGTTAINVTGSGGTITINTattGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGV 884
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 131 NGNLNTDTIIRVNTDGSVNPHLSDEGNTFIVTAGNHAVGVLACASPGSARACVSSLDEESTADTGSNENNAKAKLDMAKG 210
Cdd:COG3210 885 ATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAG 964
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 211 EITTHGTESYAAYANGTVVKAGSKLDYTNASVTLTDVDITTHGDNAHAIAARQGTVSFNQGEIHTTGPDAAIAKIYNGGK 290
Cdd:COG3210 965 DTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQN 1044
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 291 VTLKNTSAVAHQGAGIVLESSINGQEATVDILSGSSLRSANEILYNKNETSNVTITDSEVSSAADVFINNIKGHLAIDAS 370
Cdd:COG3210 1045 GVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGT 1124
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 371 NSKITGSANLSTDDSTHTYLSLSDNSTWDIKTDSTVSKLTVDNSTVYISRADGKAFEPTRLTITENYVGNNGILHLRTEL 450
Cdd:COG3210 1125 TTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDST 1204
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446691189 451 GDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEFIKDSRIFAGAYEYSLTRGNTEATNKNWYL 530
Cdd:COG3210 1205 GGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATATGS 1284
|
490
....*....|....*...
gi 446691189 531 TNFQATSGGETNSGGSSA 548
Cdd:COG3210 1285 TVDIGSTSATSAGGSLDT 1302
|
|
| |
