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Conserved domains on  [gi|446738150|ref|WP_000815406|]
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6-phosphogluconolactonase [Escherichia fergusonii]

Protein Classification

6-phosphogluconolactonase( domain architecture ID 11485154)

6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate, which is the the second step of the oxidative phase of the pentose phosphate pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 2-331 0e+00

6-phosphogluconolactonase; Provisional


:

Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 672.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   2 KQTVYIASPESQQIHVWNLNHDGTLTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIApDDGALTFAAESALP 81
Cdd:PRK11028   1 KQIVYIASPESQQIHVWNLNHEGALTLLQVVDVPGQVQPMVISPDKRHLYVGVRPEFRVLSYRIA-DDGALTFAAESPLP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  82 GSPTHISTDHQGRFVFVGSYNAGSVSVTRL-EDGLPVEVVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTVSDDG 160
Cdd:PRK11028  80 GSPTHISTDHQGRFLFSASYNANCVSVSPLdKDGIPVAPIQIIEGLEGCHSANIDPDNRTLWVPCLKEDRIRLFTLSDDG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 161 YLAAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPADFSDTRWAADIHITPDG 240
Cdd:PRK11028 160 HLVAQEPAEVTTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKDPHGEIECVQTLDMMPADFSDTRWAADIHITPDG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 241 RHLYACDRTASLITVFSVSEDGSVLTKEGYQSTETQPRGFNVDHSGKYLIAAGQKSHHIAVYEIHGEQGLLTEKGRYAVG 320
Cdd:PRK11028 240 RHLYACDRTASLISVFSVSEDGSVLSFEGHQPTETQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGETGLLTELGRYAVG 319

                        330
                 ....*....|.
gi 446738150 321 QGPMWVVVNAH 331
Cdd:PRK11028 320 QGPMWVSVLAL 330
 
Name Accession Description Interval E-value
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 2-331 0e+00

6-phosphogluconolactonase; Provisional


Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 672.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   2 KQTVYIASPESQQIHVWNLNHDGTLTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIApDDGALTFAAESALP 81
Cdd:PRK11028   1 KQIVYIASPESQQIHVWNLNHEGALTLLQVVDVPGQVQPMVISPDKRHLYVGVRPEFRVLSYRIA-DDGALTFAAESPLP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  82 GSPTHISTDHQGRFVFVGSYNAGSVSVTRL-EDGLPVEVVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTVSDDG 160
Cdd:PRK11028  80 GSPTHISTDHQGRFLFSASYNANCVSVSPLdKDGIPVAPIQIIEGLEGCHSANIDPDNRTLWVPCLKEDRIRLFTLSDDG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 161 YLAAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPADFSDTRWAADIHITPDG 240
Cdd:PRK11028 160 HLVAQEPAEVTTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKDPHGEIECVQTLDMMPADFSDTRWAADIHITPDG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 241 RHLYACDRTASLITVFSVSEDGSVLTKEGYQSTETQPRGFNVDHSGKYLIAAGQKSHHIAVYEIHGEQGLLTEKGRYAVG 320
Cdd:PRK11028 240 RHLYACDRTASLISVFSVSEDGSVLSFEGHQPTETQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGETGLLTELGRYAVG 319

                        330
                 ....*....|.
gi 446738150 321 QGPMWVVVNAH 331
Cdd:PRK11028 320 QGPMWVSVLAL 330
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
2-328 3.24e-129

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 372.70  E-value: 3.24e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   2 KQTVYIAS---PESQQIHVWNLN-HDGTLTLTQVVDVPGQVQPMVVSPDKRYLYVGVRP-EFRVLAYRIAPDDGALTFAA 76
Cdd:COG2706    7 STFVYVGTytsGESEGIYVFRLDtATGELTLLGLVAALGNPSFLALSPDGRFLYAVNEVdDGGVSAFRIDPADGTLTLLN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  77 ESALPG-SPTHISTDHQGRFVFVGSYNAGSVSVTRL-EDGLPVEVVDVVE-----------GLDGCHSANITPDNRTLWV 143
Cdd:COG2706   87 TVSSGGaSPCHLSVDPDGRFLFVANYGGGSVSVFPIdADGSLGEPVQVIQhegsgpnperqEGPHAHSVVFDPDGRFLYV 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 144 PALKQDRICLFTVS-DDGYLAaqDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMP 222
Cdd:COG2706  167 PDLGTDRIYVYRLDpATGKLP--EPPEVSLPPGSGPRHLAFHPNGRFAYVINELDSTVSVYAYDAATGTLTLIQTVSTLP 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 223 ADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLTKEGYQSTE-TQPRGFNVDHSGKYLIAAGQKSHHIAV 301
Cdd:COG2706  245 EDFTGENWAADIHISPDGRFLYVSNRGHNSIAVFAIDADGGKLTLVGHVPTGgKWPRDFAIDPDGRFLLVANQKSDNITV 324

                        330       340
                 ....*....|....*....|....*..
gi 446738150 302 YEIHGEQGLLTEKGRYAVGQGPMWVVV 328
Cdd:COG2706  325 FRIDADTGKLTPTGRSVPVPSPVCVAF 351
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 4-324 3.11e-122

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 354.61  E-value: 3.11e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150    4 TVYIAS---PESQQIHVWNLNHD-GTLTLTQVVDVPGQVQPMVVSPDKRYLYVGVR--PEFRVLAYRIAPDDGALTFAAE 77
Cdd:pfam10282   1 TLYVGTytkGDSKGIYVLTLDTEtGALTLLGLVAEVGNPSYLALSPDGRTLYAVNEegDQGGVAAFRIDPDSGALTLLNQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   78 -SALPGSPTHISTDHQGRFVFVGSYNAGSVSVTRL-EDGLPVEVVDVV--EGLDG---------CHSANITPDNRTLWVP 144
Cdd:pfam10282  81 vPTGGASPCHLSVDPDGRFLFVANYHGGSVSVFPLdADGSLGELSQVVqhEGSGPpperqesphPHSVDLTPDGKFLVVP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  145 ALKQDRICLFTVSDDGyLAAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPAD 224
Cdd:pfam10282 161 DLGTDRVRVYKLDAGG-GKLTPPASVQTPPGSGPRHLAFHPNGKYAYVVNELSSTVTVFEYDPATGTFEELQTVSTLPEG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  225 FSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLTKEGYQSTETQ-PRGFNVDHSGKYLIAAGQKSHHIAVYE 303
Cdd:pfam10282 240 FTGTNGAAAIRVSPDGKFLYVSNRGHDSIAVFAVDEAGGTLTLVERVSTEGDfPRDFNIDPDGKFLVVANQDSDNVTVFR 319

                         330       340
                  ....*....|....*....|.
gi 446738150  304 IHGEQGLLTEKGRYAVGQGPM 324
Cdd:pfam10282 320 RDPETGKLTLLGKDIEVPEPV 340
 
Name Accession Description Interval E-value
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 2-331 0e+00

6-phosphogluconolactonase; Provisional


Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 672.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   2 KQTVYIASPESQQIHVWNLNHDGTLTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIApDDGALTFAAESALP 81
Cdd:PRK11028   1 KQIVYIASPESQQIHVWNLNHEGALTLLQVVDVPGQVQPMVISPDKRHLYVGVRPEFRVLSYRIA-DDGALTFAAESPLP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  82 GSPTHISTDHQGRFVFVGSYNAGSVSVTRL-EDGLPVEVVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTVSDDG 160
Cdd:PRK11028  80 GSPTHISTDHQGRFLFSASYNANCVSVSPLdKDGIPVAPIQIIEGLEGCHSANIDPDNRTLWVPCLKEDRIRLFTLSDDG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 161 YLAAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPADFSDTRWAADIHITPDG 240
Cdd:PRK11028 160 HLVAQEPAEVTTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKDPHGEIECVQTLDMMPADFSDTRWAADIHITPDG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 241 RHLYACDRTASLITVFSVSEDGSVLTKEGYQSTETQPRGFNVDHSGKYLIAAGQKSHHIAVYEIHGEQGLLTEKGRYAVG 320
Cdd:PRK11028 240 RHLYACDRTASLISVFSVSEDGSVLSFEGHQPTETQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGETGLLTELGRYAVG 319

                        330
                 ....*....|.
gi 446738150 321 QGPMWVVVNAH 331
Cdd:PRK11028 320 QGPMWVSVLAL 330
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
2-328 3.24e-129

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 372.70  E-value: 3.24e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   2 KQTVYIAS---PESQQIHVWNLN-HDGTLTLTQVVDVPGQVQPMVVSPDKRYLYVGVRP-EFRVLAYRIAPDDGALTFAA 76
Cdd:COG2706    7 STFVYVGTytsGESEGIYVFRLDtATGELTLLGLVAALGNPSFLALSPDGRFLYAVNEVdDGGVSAFRIDPADGTLTLLN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  77 ESALPG-SPTHISTDHQGRFVFVGSYNAGSVSVTRL-EDGLPVEVVDVVE-----------GLDGCHSANITPDNRTLWV 143
Cdd:COG2706   87 TVSSGGaSPCHLSVDPDGRFLFVANYGGGSVSVFPIdADGSLGEPVQVIQhegsgpnperqEGPHAHSVVFDPDGRFLYV 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 144 PALKQDRICLFTVS-DDGYLAaqDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMP 222
Cdd:COG2706  167 PDLGTDRIYVYRLDpATGKLP--EPPEVSLPPGSGPRHLAFHPNGRFAYVINELDSTVSVYAYDAATGTLTLIQTVSTLP 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 223 ADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLTKEGYQSTE-TQPRGFNVDHSGKYLIAAGQKSHHIAV 301
Cdd:COG2706  245 EDFTGENWAADIHISPDGRFLYVSNRGHNSIAVFAIDADGGKLTLVGHVPTGgKWPRDFAIDPDGRFLLVANQKSDNITV 324

                        330       340
                 ....*....|....*....|....*..
gi 446738150 302 YEIHGEQGLLTEKGRYAVGQGPMWVVV 328
Cdd:COG2706  325 FRIDADTGKLTPTGRSVPVPSPVCVAF 351
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 4-324 3.11e-122

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 354.61  E-value: 3.11e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150    4 TVYIAS---PESQQIHVWNLNHD-GTLTLTQVVDVPGQVQPMVVSPDKRYLYVGVR--PEFRVLAYRIAPDDGALTFAAE 77
Cdd:pfam10282   1 TLYVGTytkGDSKGIYVLTLDTEtGALTLLGLVAEVGNPSYLALSPDGRTLYAVNEegDQGGVAAFRIDPDSGALTLLNQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   78 -SALPGSPTHISTDHQGRFVFVGSYNAGSVSVTRL-EDGLPVEVVDVV--EGLDG---------CHSANITPDNRTLWVP 144
Cdd:pfam10282  81 vPTGGASPCHLSVDPDGRFLFVANYHGGSVSVFPLdADGSLGELSQVVqhEGSGPpperqesphPHSVDLTPDGKFLVVP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  145 ALKQDRICLFTVSDDGyLAAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPAD 224
Cdd:pfam10282 161 DLGTDRVRVYKLDAGG-GKLTPPASVQTPPGSGPRHLAFHPNGKYAYVVNELSSTVTVFEYDPATGTFEELQTVSTLPEG 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  225 FSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLTKEGYQSTETQ-PRGFNVDHSGKYLIAAGQKSHHIAVYE 303
Cdd:pfam10282 240 FTGTNGAAAIRVSPDGKFLYVSNRGHDSIAVFAVDEAGGTLTLVERVSTEGDfPRDFNIDPDGKFLVVANQDSDNVTVFR 319

                         330       340
                  ....*....|....*....|.
gi 446738150  304 IHGEQGLLTEKGRYAVGQGPM 324
Cdd:pfam10282 320 RDPETGKLTLLGKDIEVPEPV 340
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
3-143 2.59e-11

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 62.79  E-value: 2.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   3 QTVYIASPESQQIHVWNLNhdgTLTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYriapDDGALTFAAESALPG 82
Cdd:COG3391   80 RRLYVANSGSGRVSVIDLA---TGKVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVI----DTATGKVVATIPVGA 152

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446738150  83 SPTHISTDHQGRFVFVGSYNAGS----VSVTRLEDGlpvEVVDVVEGLDGCHSANITPDNRTLWV 143
Cdd:COG3391  153 GPHGIAVDPDGKRLYVANSGSNTvsviVSVIDTATG---KVVATIPVGGGPVGVAVSPDGRRLYV 214
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
32-250 1.11e-10

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 60.86  E-value: 1.11e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  32 VDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGRFVFVGSYNAGSVSVTRL 111
Cdd:COG3391   18 LAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRVSVIDL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 112 EDGlpvEVVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTVSDDgylaaqdpAEVTTVE-GAGPRHMVFHPNEQYA 190
Cdd:COG3391   98 ATG---KVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVIDTATG--------KVVATIPvGAGPHGIAVDPDGKRL 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446738150 191 YCVNELNSSVDVWelkdphgniecVQTLDM----MPADFSDTRWAADIHITPDGRHLYACDRTA 250
Cdd:COG3391  167 YVANSGSNTVSVI-----------VSVIDTatgkVVATIPVGGGPVGVAVSPDGRRLYVANRGS 219
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
45-201 3.55e-09

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 56.24  E-value: 3.55e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  45 PDKRYLYVGVRPEFRVlaYRIAPDDGALTfaAESALPGSPTHISTDHQGRFVFVGSYNAGSVSVTRLEDGlpvEVVDVVE 124
Cdd:COG3391   77 ADGRRLYVANSGSGRV--SVIDLATGKVV--ATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVIDTATG---KVVATIP 149

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446738150 125 GLDGCHSANITPDNRTLWVPALKQDRICLFTVSddgyLAAQDPAEVTTVE-GAGPRHMVFHPNEQYAYCVNELNSSVD 201
Cdd:COG3391  150 VGAGPHGIAVDPDGKRLYVANSGSNTVSVIVSV----IDTATGKVVATIPvGGGPVGVAVSPDGRRLYVANRGSNTSN 223
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 4-145 4.26e-08

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 53.36  E-value: 4.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   4 TVYIASPESQQIH--VWNLNHDGTLTLtqVVDvpGQVQP--MVVSPDKRYLYVGVRPEFRVLAYRIApDDGALT----FA 75
Cdd:COG3386  105 RLYFTDMGEYLPTgaLYRVDPDGSLRV--LAD--GLTFPngIAFSPDGRTLYVADTGAGRIYRFDLD-ADGTLGnrrvFA 179

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446738150  76 AESALPGSPTHISTDHQGRfVFVGSYNAGSVSVtRLEDGlpvEVVDVVEgLDGCHSANIT---PDNRTLWVPA 145
Cdd:COG3386  180 DLPDGPGGPDGLAVDADGN-LWVALWGGGGVVR-FDPDG---ELLGRIE-LPERRPTNVAfggPDLRTLYVTT 246
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
60-298 1.75e-07

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 51.23  E-value: 1.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  60 VLAYRIAPDDGALTFAAESALPGSPTHISTDHQGRFVFVGSYNAGSVSVTRLEDGLPVEVVDVVEGLDGCHSANITPDNR 139
Cdd:COG3391    1 ALVASSLLVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 140 TLWVPALKQDRICLFTVSDDGYLAaqdpaevTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDphGNIEcvqtld 219
Cdd:COG3391   81 RLYVANSGSGRVSVIDLATGKVVA-------TIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVIDTAT--GKVV------ 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 220 mmpADFSDTRWAADIHITPDGRHLYACDRTASLITVF-SV--SEDGSVLTKegyQSTETQPRGFNVDHSGKYLIAAGQKS 296
Cdd:COG3391  146 ---ATIPVGAGPHGIAVDPDGKRLYVANSGSNTVSVIvSVidTATGKVVAT---IPVGGGPVGVAVSPDGRRLYVANRGS 219


                 ..
gi 446738150 297 HH 298
Cdd:COG3391  220 NT 221
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
154-330 4.50e-06

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 47.00  E-value: 4.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 154 FTVSDDGYLAAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDphGNIECVQTLDMMPADfsdtrwaad 233
Cdd:COG3391   46 GAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRVSVIDLAT--GKVVATIPVGGGPRG--------- 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 234 IHITPDGRHLYACDRTASLITVFSVSeDGSVLTKegyQSTETQPRGFNVDHSGKYLIAAGQKSHHIA--VYEIHGEQGll 311
Cdd:COG3391  115 LAVDPDGGRLYVADSGNGRVSVIDTA-TGKVVAT---IPVGAGPHGIAVDPDGKRLYVANSGSNTVSviVSVIDTATG-- 188

                        170
                 ....*....|....*....
gi 446738150 312 TEKGRYAVGQGPMWVVVNA 330
Cdd:COG3391  189 KVVATIPVGGGPVGVAVSP 207
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 3-178 2.79e-05

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 44.88  E-value: 2.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   3 QTVYIASPESQQIHVWNLnhdGTLTLTQVVDVPGQVQPMVVSPDKRyLYVgVRPEFRVlaYRIAPDDGALT-FAAESALP 81
Cdd:COG3386   19 GRLYWVDIPGGRIHRYDP---DGGAVEVFAEPSGRPNGLAFDPDGR-LLV-ADHGRGL--VRFDPADGEVTvLADEYGKP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  82 G-SPTHISTDHQGRFVF--VGSYNAGSvSVTRLEDGLPVEVVDvveglDGCHSAN---ITPDNRTLWVPALKQDRICLFT 155
Cdd:COG3386   92 LnRPNDGVVDPDGRLYFtdMGEYLPTG-ALYRVDPDGSLRVLA-----DGLTFPNgiaFSPDGRTLYVADTGAGRIYRFD 165

                        170       180
                 ....*....|....*....|...
gi 446738150 156 VSDDGYLAAQDPAEVTTVEGAGP 178
Cdd:COG3386  166 LDADGTLGNRRVFADLPDGPGGP 188
WD40 COG2319
WD40 repeat [General function prediction only];
3-264 1.13e-04

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 43.75  E-value: 1.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   3 QTVYIASpESQQIHVWNLnHDGTLTLTqVVDVPGQVQPMVVSPDKRYLYVGVRPEfRVLAYRIAPDDGALTFAAESALPG 82
Cdd:COG2319  175 KLLASGS-DDGTVRLWDL-ATGKLLRT-LTGHTGAVRSVAFSPDGKLLASGSADG-TVRLWDLATGKLLRTLTGHSGSVR 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  83 SPThISTDhqGRFVFVGSYNaGSVSVTRLEDGLPVEVVDvvEGLDGCHSANITPDNRTLwvpalkqdriclFTVSDDGYL 162
Cdd:COG2319  251 SVA-FSPD--GRLLASGSAD-GTVRLWDLATGELLRTLT--GHSGGVNSVAFSPDGKLL------------ASGSDDGTV 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 163 A---AQDPAEVTTVEG--AGPRHMVFHPNEQYAYCVNElNSSVDVWELKDPhgniECVQTLDmmpadfSDTRWAADIHIT 237
Cdd:COG2319  313 RlwdLATGKLLRTLTGhtGAVRSVAFSPDGKTLASGSD-DGTVRLWDLATG----ELLRTLT------GHTGAVTSVAFS 381

                        250       260
                 ....*....|....*....|....*..
gi 446738150 238 PDGRHLyacdrtaslitvFSVSEDGSV 264
Cdd:COG2319  382 PDGRTL------------ASGSADGTV 396
WD40 COG2319
WD40 repeat [General function prediction only];
7-293 5.11e-04

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 41.44  E-value: 5.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150   7 IASPESQQIHVWNLNHDGTLTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPeFRVLAYRIApddGALTFAAESALPGSPTH 86
Cdd:COG2319   50 RLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASAD-GTVRLWDLA---TGLLLRTLTGHTGAVRS 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150  87 ISTDHQGRFVFVGSYNaGSVSVTRLEDGlpvEVVDVVEGLDGC-HSANITPDNRTLwvpalkqdriclFTVSDDGYLA-- 163
Cdd:COG2319  126 VAFSPDGKTLASGSAD-GTVRLWDLATG---KLLRTLTGHSGAvTSVAFSPDGKLL------------ASGSDDGTVRlw 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 164 -AQDPAEVTTVEG--AGPRHMVFHPNEQYAYCVNElNSSVDVWELKDPhgniECVQTLDmmpadfSDTRWAADIHITPDG 240
Cdd:COG2319  190 dLATGKLLRTLTGhtGAVRSVAFSPDGKLLASGSA-DGTVRLWDLATG----KLLRTLT------GHSGSVRSVAFSPDG 258

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446738150 241 RHLYAC--DRTaslITVFSVSEDGSVLTKEGYQSTetqPRGFNVDHSGKYLIAAG 293
Cdd:COG2319  259 RLLASGsaDGT---VRLWDLATGELLRTLTGHSGG---VNSVAFSPDGKLLASGS 307
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 228-307 3.11e-03

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 38.72  E-value: 3.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738150 228 TRWAADIHI------TPDGRHLYACDRTASLITVFSVSEDGSVLTKE---GYQSTETQPRGFNVDHSGkYLIAAGQKSHH 298
Cdd:COG3386  130 RVLADGLTFpngiafSPDGRTLYVADTGAGRIYRFDLDADGTLGNRRvfaDLPDGPGGPDGLAVDADG-NLWVALWGGGG 208


                 ....*....
gi 446738150 299 IAVYEIHGE 307
Cdd:COG3386  209 VVRFDPDGE 217
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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